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https://www.readbyqxmd.com/read/28345977/spinal-cord-injuries-overcoming-barriers-to-seamless-care-for-patients
#1
Lorraine Donovan, Lee Francis, Paula Muter, Sheila Nevin, Rebecca Warren
Patients with spinal cord injuries (SCIs) often have complex needs that require multidisciplinary support in specialist centres. Optimal management depends on seamless transitions between service providers. Delays at any point potentially compromise clinical outcomes and efficient resource utilisation. The Spinal Advisory Working Group aims to develop and implement practical initiatives to improve SCI care, initially focusing on admission and discharge. A literature review identified few relevant papers. In addition, the generalisability of the findings of these papers to SCI centres in the UK is unclear...
March 23, 2017: British Journal of Nursing: BJN
https://www.readbyqxmd.com/read/28342113/crizotinib-for-untreated-anaplastic-lymphoma-kinase-positive-non-small-cell-lung-cancer-an-evidence-review-group-perspective-of-a-nice-single-technology-appraisal
#2
REVIEW
Philip Morgan, Nerys Woolacott, Mousumi Biswas, Teumzghi Mebrahtu, Melissa Harden, Robert Hodgson
As part of the National Institute for Health and Care Excellence (NICE) single technology appraisal process, the manufacturer of crizotinib submitted evidence on the clinical and cost effectiveness of crizotinib in untreated anaplastic lymphoma kinase-positive (ALK-positive) non-small-cell lung cancer (NSCLC). Crizotinib has previously been assessed by NICE for patients with previously treated ALK-positive NSCLC (TA 296). It was not approved in this previous appraisal, but had been made available through the cancer drugs fund...
March 24, 2017: PharmacoEconomics
https://www.readbyqxmd.com/read/28341689/designing-a-physical-activity-intervention-for-children-with-asthma-a-qualitative-study-of-the-views-of-healthcare-professionals-parents-and-children-with-asthma
#3
Russell Jago, Aidan Searle, A John Henderson, Katrina M Turner
OBJECTIVES: Qualitative methods were used to examine: (1) the attitudes of health professionals to promoting physical activity for children with asthma; (2) reasons why children with asthma are less active and (3) how a physical activity programme for children with asthma could be designed. DESIGN: Semistructured interviews were conducted with health professionals, children with asthma and their parents between October 2015 and March 2016. Interviews were transcribed verbatim and thematically analysed...
March 24, 2017: BMJ Open
https://www.readbyqxmd.com/read/28337006/challenges-in-x-ray-diagnosis-a-review-of-referrals-for-specialist-opinion
#4
M Dave, K Horner
The aim of this study was to determine the common reasons why a dental professional might request a second opinion on a dental radiograph from a Dental and Maxillofacial (DMF) radiologist. The study was a retrospective analysis of consecutive referrals for an opinion received by post or email by one DMF radiologist based in a UK dental hospital. The study period was from March 2009 to November 2015. Referrals came from a mixture of sources: mainly from general dental practitioners and specialists working in primary care, but with some referrals from hospital-based practitioners...
March 24, 2017: British Dental Journal
https://www.readbyqxmd.com/read/28332762/the-effect-of-senior-obstetric-presence-on-maternal-and-neonatal-outcomes-in-uk-nhs-maternity-units-a-systematic-review-and-meta-analysis
#5
Holly E Reid, Dexter J L Hayes, Anja Wittkowski, Sarah Vause, Jo Whitcombe, Alexander E P Heazell
BACKGROUND: There is little consensus regarding the hypothesised link between obstetric consultant presence and maternal and neonatal outcomes. OBJECTIVES: To pool existing data on the impact of consultant presence on the outcomes of women who have given birth in UK NHS maternity units. SEARCH STRATEGY: Twelve databases, grey literature and reference lists were searched. SELECTION CRITERIA: Studies conducted in UK NHS maternity units comparing outcomes during lesser consultant presence versus increased consultant presence that reported mode of delivery and adverse maternal or neonatal outcomes...
March 23, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28332761/a-uk-national-survey-of-care-pathways-and-support-offered-to-patients-receiving-revision-surgery-for-prosthetic-joint-infection-in-the-highest-volume-nhs-orthopaedic-centres
#6
Andrew J Moore, Michael R Whitehouse, Rachael Gooberman-Hill, Jason Heddington, Andrew D Beswick, Ashley W Blom, Tim J Peters
BACKGROUND: Deep prosthetic joint infection (PJI) is a devastating complication of joint replacement surgery. It is difficult to treat, and patients often require multiple major revision surgeries to eradicate the infection. Treatment can have negative and long-term impact on patients' quality of life. Understanding current service provision provides valuable information needed to design and evaluate support interventions for patients. AIM: This survey aimed to identify usual care pathways and support in UK National Health Service (NHS) orthopaedic centres for patients receiving revision surgery for PJI after hip or knee replacement...
March 23, 2017: Musculoskeletal Care
https://www.readbyqxmd.com/read/28322808/uk-nhs-home-office-agreement-undermines-patient-trust
#7
Becky McCall
No abstract text is available yet for this article.
March 18, 2017: Lancet
https://www.readbyqxmd.com/read/28320707/total-center-percutaneous-coronary-intervention-volume-and-30-day-mortality-a-contemporary-national-cohort-study-of-427%C3%A2-467-elective-urgent-and-emergency-cases
#8
Darragh O'Neill, Owen Nicholas, Chris P Gale, Peter Ludman, Mark A de Belder, Adam Timmis, Keith A A Fox, Iain A Simpson, Simon Redwood, Simon G Ray
BACKGROUND: The relationship between procedural volume and prognosis after percutaneous coronary intervention (PCI) remains uncertain, with some studies finding in favor of an inverse association and some against. This UK study provides a contemporary reassessment in one of the few countries in the world with a nationally representative PCI registry. METHODS AND RESULTS: A nationwide cohort study was performed using the national British Cardiovascular Intervention Society registry...
March 2017: Circulation. Cardiovascular Quality and Outcomes
https://www.readbyqxmd.com/read/28319050/extracellular-matrix-proteomics-identifies-molecular-signature-of-symptomatic-carotid-plaques
#9
Sarah R Langley, Karin Willeit, Athanasios Didangelos, Ljubica Perisic Matic, Philipp Skroblin, Javier Barallobre-Barreiro, Mariette Lengquist, Gregor Rungger, Alexander Kapustin, Ludmilla Kedenko, Chris Molenaar, Ruifang Lu, Temo Barwari, Gonca Suna, Xiaoke Yin, Bernhard Iglseder, Bernhard Paulweber, Peter Willeit, Joseph Shalhoub, Gerard Pasterkamp, Alun H Davies, Claudia Monaco, Ulf Hedin, Catherine M Shanahan, Johann Willeit, Stefan Kiechl, Manuel Mayr
BACKGROUND: The identification of patients with high-risk atherosclerotic plaques prior to the manifestation of clinical events remains challenging. Recent findings question histology- and imaging-based definitions of the "vulnerable plaque," necessitating an improved approach for predicting onset of symptoms. METHODS: We performed a proteomics comparison of the vascular extracellular matrix and associated molecules in human carotid endarterectomy specimens from 6 symptomatic versus 6 asymptomatic patients to identify a protein signature for high-risk atherosclerotic plaques...
March 20, 2017: Journal of Clinical Investigation
https://www.readbyqxmd.com/read/28317421/a-prospective-cohort-study-evaluating-the-cost-effectiveness-of-carbetocin-for-prevention-of-postpartum-haemorrhage-in-caesarean-sections
#10
Yasmin Luni, Aditya Borakati, Arti Matah, Katie Skeats, Padma Eedarapalli
Postpartum haemorrhage (PPH) is the leading cause of maternal mortality worldwide. Prophylaxis with oxytocic medication is recommended by the WHO to prevent its occurrence. Carbetocin is a newer oxytocic, with potential to lower PPH rates, reduce the total use of oxytocic drugs and lead to financial savings. Meta-analyses have confirmed a reduction in the use of additional oxytocic medication with the use of carbetocin compared to oxytocin. However, there are few studies evaluating the costs of carbetocin prophylaxis...
March 20, 2017: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28290467/long-term-survival-after-traumatic-spinal-cord-injury-a-70-year-british-study
#11
G Savic, M J DeVivo, H L Frankel, M A Jamous, B M Soni, S Charlifue
STUDY DESIGN: Retrospective and prospective observational. OBJECTIVES: Analyse long-term survival after traumatic spinal cord injury (SCI) in Great Britain over the 70-year study period, identify mortality risk factors and estimate current life expectancy. SETTING: Two spinal centres in Great Britain. METHODS: The sample consisted of patients with traumatic SCI injured 1943-2010 who survived the first year post-injury, had residual neurological deficit on discharge and were British residents...
March 14, 2017: Spinal Cord
https://www.readbyqxmd.com/read/28290340/are-reporting-radiographers-fulfilling-the-role-of-advanced-practitioner
#12
R C Milner, B Snaith
BACKGROUND: Advanced practice roles are emerging in all disciplines at a rapid pace and reporting radiographers are ideally placed to work at such level. Advanced practitioners should demonstrate expert practice and show progression into three other areas of higher level practice. Most existing literature has focussed on the image interpretation aspect of the role, however there is little evidence that plain film reporting radiographers are undertaking activities beyond image interpretation and fulfilling the role of advanced practitioner...
February 2017: Radiography
https://www.readbyqxmd.com/read/28289013/prescription-rates-of-adrenaline-auto-injectors-for-children-in-uk-general-practice-a-retrospective-cohort-study
#13
Lavanya Diwakar, Carole Cummins, Ronan Ryan, Tom Marshall, Tracy Roberts
BACKGROUND: Adrenaline auto-injectors (AAI) should be provided to individuals considered to be at high risk of anaphylaxis. There is some evidence that the rate of AAI prescription is increasing, but the true extent has not been previously quantified. AIM: To estimate the trends in annual GP-issued prescriptions for AAI among UK children between 2000 and 2012. DESIGN AND SETTING: Retrospective cohort study using data from primary care practices that contributed to The Health Improvement Network (THIN) database...
March 13, 2017: British Journal of General Practice: the Journal of the Royal College of General Practitioners
https://www.readbyqxmd.com/read/28286331/stems-pilot-trial-a-pilot-cluster-randomised-controlled-trial-to-investigate-the-addition-of-patient-direct-access-to-physiotherapy-to-usual-gp-led-primary-care-for-adults-with-musculoskeletal-pain
#14
Annette Bishop, Reuben O Ogollah, Sue Jowett, Jesse Kigozi, Stephanie Tooth, Joanne Protheroe, Elaine M Hay, Chris Salisbury, Nadine E Foster
INTRODUCTION: Around 17% of general practitioner (GP) consultations are for musculoskeletal conditions, which will rise as the population ages. Patient direct access to physiotherapy provides one solution, yet adoption in the National Health Service (NHS) has been slow. SETTING: A pilot, pragmatic, non-inferiority, cluster randomised controlled trial (RCT) in general practice and physiotherapy services in the UK. OBJECTIVES: Investigate feasibility of a main RCT...
March 12, 2017: BMJ Open
https://www.readbyqxmd.com/read/28285379/evolocumab-for-treating-primary-hypercholesterolaemia-and-mixed-dyslipidaemia-an-evidence-review-group-perspective-of-a-nice-single-technology-appraisal
#15
Christopher Carroll, Paul Tappenden, Rachid Rafia, Jean Hamilton, Duncan Chambers, Mark Clowes, Paul Durrington, Nadeem Qureshi, Anthony S Wierzbicki
As part of its single technology appraisal (STA) process, the UK National Institute for Health and Care Excellence (NICE) invited the manufacturer of evolocumab (Amgen) to submit evidence on the clinical and cost effectiveness of evolocumab. The appraisal assessed evolocumab as monotherapy or in combination with a statin with or without ezetimibe, or in combination with ezetimibe (without statin therapy), in adult patients with primary hypercholesterolaemia (which includes mixed dyslipidaemia), for whom statins do not provide optimal control of their low-density lipoprotein cholesterol (LDL-C) levels and/or for whom statins are contraindicated or not tolerated...
March 11, 2017: PharmacoEconomics
https://www.readbyqxmd.com/read/28284538/the-policy-work-of-piloting-mobilising-and-managing-conflict-and-ambiguity-in-the-english-nhs
#16
Simon Bailey, Kath Checkland, Damian Hodgson, Anne McBride, Rebecca Elvey, Stephen Parkin, Katy Rothwell, Dean Pierides
In spite of their widespread use in policy making in the UK and elsewhere, there is a relatively sparse literature specifically devoted to policy pilots. Recent research on policy piloting has focused on the role of pilots in making policy work in accordance with national agendas. Taking this as a point of departure, the present paper develops the notion of pilots doing policy work. It does this by situating piloting within established theories of policy formulation and implementation, and illustrating using an empirical case...
February 3, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28283110/access-delivery-and-perceived-efficacy-of-physiotherapy-and-use-of-complementary-and-alternative-therapies-by-people-with-progressive-multiple-sclerosis-in-the-united-kingdom-an-online-survey
#17
Evan Campbell, Elaine Coulter, Paul Mattison, Angus McFadyen, Linda Miller, Lorna Paul
INTRODUCTION: All people with progressive MS in the United Kingdom should have access to physiotherapy through the National Health Service (NHS). However levels of access and delivery are unknown. Furthermore there is no research on perceived efficacy of physiotherapy or the use of complementary and alternative medicine in people with progressive MS in the United Kingdom. METHODS: An online survey was carried out via the UK MS Register. Inclusion criteria were diagnosis of progressive MS, a member of UK MS Register and 18 years or older...
February 2017: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/28281597/would-the-introduction-of-the-index-of-orthognathic-functional-treatment-need-ioftn-affect-referrals-and-acceptance-of-people-for-orthognathic-treatment
#18
S Barber, Z Jawad, T Hodge, C Bates
Introduction The Index of Orthognathic Functional Treatment Need (IOFTN) was developed to measure functional difficulties arising from malocclusions related to facial deformity. The IOFTN is not currently being used to determine suitability for orthognathic treatment, however, it is a useful aid for assessing and referring patients and takes into account functional and facial appearance. This paper aims to evaluate the potential impact of introduction of the IOFTN on the future provision of orthognathic services...
March 10, 2017: British Dental Journal
https://www.readbyqxmd.com/read/28275045/food-insecurity-and-mental-health-an-analysis-of-routine-primary-care-data-of-pregnant-women-in-the-born-in-bradford-cohort
#19
Madeleine Power, Eleonora Uphoff, Brian Kelly, Kate E Pickett
BACKGROUND: Since 2008, use of food banks has risen sharply in the UK; however, evidence on the epidemiology of UK food insecurity is sparse. The aim of this study was to describe the trajectory of common mental disorder across the pre-pregnancy, pregnancy and postnatal period for food secure compared with food insecure women. METHODS: Data from the Born in Bradford (BiB) cohort, the nested BiB1000 study and primary care records were linked based on National Health Service (NHS) numbers...
April 2017: Journal of Epidemiology and Community Health
https://www.readbyqxmd.com/read/28274333/smoking-and-common-mental-disorders-in-patients-with-chronic-conditions-an-analysis-of-data-collected-via-a-web-based-screening-system
#20
Faith Matcham, Amy Carroll, Natali Chung, Victoria Crawford, James Galloway, Anna Hames, Karina Jackson, Clare Jacobson, Dulka Manawadu, Lance McCracken, John Moxham, Lauren Rayner, Deborah Robson, Anna Simpson, Nicky Wilson, Matthew Hotopf
OBJECTIVE: Smoking is the largest preventable cause of death and disability in the UK and remains pervasive in people with mental disorders and in general hospital patients. We aimed to quantify the prevalence of mental disorders and smoking, examining associations between mental disorders and smoking in patients with chronic physical conditions. METHOD: Data were collected via routine screening systems implemented across two London NHS Foundation Trusts. The prevalence of mental disorder, current smoking, nicotine dependence and wanting help with quitting smoking were quantified, and the relationships between mental disorder and smoking were examined, adjusting for age, gender and physical illness, with multiple regression models...
March 2017: General Hospital Psychiatry
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