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Kristina H Haugaa

Trine F Haland, Jørg Saberniak, Ida S Leren, Thor Edvardsen, Kristina H Haugaa
BACKGROUND: Modern imaging technology has improved detection of left ventricular non-compaction cardiomyopathy (LVNC). Hypertrophic cardiomyopathy (HCM) shares morphological features with LVNC, but prognosis and treatment strategies differ between LVNC and HCM. METHODS AND RESULTS: We aimed to compare global and regional LV myocardial function in LVNC and HCM. We hypothesized that apical function is reduced in LVNC due to the embryonic reduced compaction of the apex...
November 9, 2016: International Journal of Cardiology
Arild Hetland, Kristina H Haugaa, Maria Vistnes, Kristian Hovde Liland, Margareth Olseng, Morten B Jacobsen, Thor Edvardsen
Objectives- The effect of long term adaptive servo-ventilation (ASV) on cardiovascular mortality and admission rates in patients with chronic heart failure (CHF) and Cheyne-Stokes respiration (CSR) has not been much studied. The aim of this study was primarily to investigate whether ASV therapy significantly reduced these parameters. Design- We included 75 CHF patients on optimal medication and CSR ≥25% of sleeping time, in New York Heart Association (NYHA) class II-IV and left ventricular ejection fraction (LVEF) ≤ 45%...
November 17, 2016: Scandinavian Cardiovascular Journal: SCJ
Kristina H Haugaa, Thor Edvardsen
No abstract text is available yet for this article.
November 2016: European Journal of Heart Failure
Ida S Leren, Jørg Saberniak, Trine F Haland, Thor Edvardsen, Kristina H Haugaa
OBJECTIVES: The aim of this study was to investigate early markers of arrhythmic events (AEs) and improve risk stratification in early arrhythmogenic right ventricular cardiomyopathy (ARVC). BACKGROUND: AEs are frequent in patients with ARVC, but risk stratification in subjects with early ARVC is challenging. METHODS: Early ARVC disease was defined as possible or borderline ARVC diagnosis according to the ARVC Task Force Criteria 2010. We performed resting and signal averaged electrocardiogram (ECG)...
October 14, 2016: JACC. Cardiovascular Imaging
Thor Edvardsen, Sebastian I Sarvari, Kristina H Haugaa
Knowledge about myocardial function is important for diagnosis, treatment and prediction of the majority of all cardiac diseases. Ejection fraction (EF) by echocardiography has been the preferred diagnostic tool for these purposes, but do have some important limitations. Strain imaging has emerged as a relatively new and important echocardiographic method that will give cardiologists incremental and additional information to EF in several important diseases affecting the myocardium. This paper will give the readers a brief overview on how and when the clinicians can use strain imaging by echocardiography in their daily practice...
September 21, 2016: Scandinavian Cardiovascular Journal: SCJ
Thor Edvardsen, Nuno Cardim, Bernard Cosyns, Victoria Delgado, Erwan Donal, Raluca Dulgheru, Maurizio Galderisi, Kristina H Haugaa, Philipp A Kaufmann, Patrizio Lancellotti, Massimo Lombardi, Denisa Muraru, Sven Plein, Gerald Maurer, Bogdan A Popescu, Gilbert Habib
The recommendations given in this document are intended as a guide for the writing committees with the aim to harmonize the style and content of EACVI expert consensus and recommendation documents.
October 2016: European Heart Journal Cardiovascular Imaging
Andreas Früh, Geir Siem, Henrik Holmström, Gaute Døhlen, Kristina H Haugaa
BACKGROUND: Patients with Jervell and Lange-Nielsen syndrome (JLNS) exhibit severe phenotypes that are characterized by congenital deafness, very long QT-intervals and a high risk of life-threatening arrhythmias. Current treatment strategies include high doses of ß-blocker medication, left cardiac sympathetic denervation (LCSD), and ICD implantation which is challenging in young children. Objective The purpose of this study was to evaluate the safety and effect of pacing in addition to ß-blocker treatment in children with JLNS...
July 20, 2016: Heart Rhythm: the Official Journal of the Heart Rhythm Society
Roland Tilz, Serge Boveda, Jean-Claude Deharo, Dan Dobreanu, Kristina H Haugaa, Nikolaos Dagres
The aim of this EP Wire was to assess the management, indications, and techniques for implantable cardioverter defibrillator (ICD) and cardiac resynchronization therapy (CRT) device replacement in Europe. A total of 24 centres in 14 European countries completed the questionnaire. All centres were members of the European Heart Rhythm Association Electrophysiology Research Network. Replacement procedures were performed by electrophysiologists in 52% of the centres, by cardiologists in 33%, and both in the remaining centres...
June 2016: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
Jørg Saberniak, Ida S Leren, Trine F Haland, Jan Otto Beitnes, Einar Hopp, Rasmus Borgquist, Thor Edvardsen, Kristina H Haugaa
AIMS: Differentiation between early-phase arrhythmogenic right ventricular cardiomyopathy (ARVC) and right ventricular outflow tract (RVOT)-ventricular tachycardia (VT) can be challenging, and correct diagnosis is important. We compared electrocardiogram (ECG) parameters and morphological right ventricular (RV) abnormalities and investigated if ECG and cardiac imaging can help to discriminate early-phase ARVC from RVOT-VT patients. METHODS AND RESULTS: We included 44 consecutive RVOT-VT (47 ± 14 years) and 121 ARVC patients (42 ± 17 years)...
February 21, 2016: European Heart Journal Cardiovascular Imaging
Trine F Haland, Vibeke M Almaas, Nina E Hasselberg, Jørg Saberniak, Ida S Leren, Einar Hopp, Thor Edvardsen, Kristina H Haugaa
AIMS: Hypertrophic cardiomyopathy (HCM) patients are at risk of ventricular arrhythmias (VAs). We aimed to explore whether systolic function by strain echocardiography is related to VAs and to the extent of fibrosis by cardiac magnetic resonance imaging (CMR). METHODS AND RESULTS: We included 150 HCM patients and 50 healthy individuals. VAs were defined as non-sustained and sustained ventricular tachycardia and aborted cardiac arrest. Left ventricular function was assessed by ejection fraction (EF) and by global longitudinal strain (GLS) assessed by speckle tracking echocardiography...
June 2016: European Heart Journal Cardiovascular Imaging
Erwan Donal, Gregory Y H Lip, Maurizio Galderisi, Andreas Goette, Dipen Shah, Mohamed Marwan, Mathieu Lederlin, Sergio Mondillo, Thor Edvardsen, Marta Sitges, Julia Grapsa, Madalina Garbi, Roxy Senior, Alessia Gimelli, Tatjana S Potpara, Isabelle C Van Gelder, Bulent Gorenek, Philippe Mabo, Patrizio Lancellotti, Karl-Heinz Kuck, Bogdan A Popescu, Gerhard Hindricks, Gilbert Habib, Nuno M Cardim, Bernard Cosyns, Victoria Delgado, Kristina H Haugaa, Denisa Muraru, Koen Nieman, Giuseppe Boriani, Ariel Cohen
Atrial fibrillation (AF) is the commonest cardiac rhythm disorder. Evaluation of patients with AF requires an electrocardiogram, but imaging techniques should be considered for defining management and driving treatment. The present document is an expert consensus from the European Association of Cardiovascular Imaging (EACVI) and the European Heart Rhythm Association. The clinical value of echocardiography, cardiac magnetic resonance (CMR), computed tomography (CT), and nuclear imaging in AF patients are challenged...
April 2016: European Heart Journal Cardiovascular Imaging
Radosław Lenarczyk, Tatjana S Potpara, Kristina H Haugaa, Antonio Hernández-Madrid, Elena Sciaraffia, Nikolaos Dagres
The aim of this European Heart Rhythm Association (EHRA) survey was to collect data on the use of wearable cardioverter-defibrillators (WCDs) among members of the EHRA electrophysiology research network. Of the 50 responding centres, 23 (47%) reported WCD use. Devices were fully reimbursed in 17 (43.6%) of 39 respondents, and partially reimbursed in 3 centres (7.7%). Eleven out of 20 centres (55%) reported acceptable patients' compliance (WCD worn for >90% of time). The most common indications for WCD (8 out of 10 centres; 80%) were covering the period until re-implantation of ICD explanted due to infection, in patients with left ventricular impairment due to myocarditis or recent myocardial infarction and those awaiting heart transplantation...
January 2016: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
Marcio V L Barros, Ida S Leren, Thor Edvardsen, Kristina H Haugaa, Andre A L Carmo, Thais A R Lage, Maria Carmo P Nunes, Manoel O C Rocha, Antonio L P Ribeiro
BACKGROUND: Sudden death is one of the characteristics of Chagas disease (ChD). With the development of strategies for the prevention of malignant arrhythmias, especially with implantable cardioverter-defibrillators (ICDs), there is interest in developing strategies to predict sudden cardiac death. The aim of this study was to test the hypothesis that global longitudinal strain (GLS) and mechanical dispersion (MD) may be associated with malignant ventricular arrhythmias in patients with ChD...
April 2016: Journal of the American Society of Echocardiography
Srikanth Seethala, Prabhpreet Singh, Vladimir Shusterman, Margareth Ribe, Kristina H Haugaa, Jan Němec
BACKGROUND: Increased variability of QT interval (QTV) has been linked to arrhythmias in animal experiments and multiple clinical situations. Congenital long QT syndrome (LQTS), a pure repolarization disease, may provide important information on the relationship between delayed repolarization and QTV. METHODS AND RESULTS: Twenty-four-hour Holter monitor tracings from 78 genotyped congenital LQTS patients (52 females; 51 LQT1, 23 LQT2, 2 LQT5, 2 JLN, 27 symptomatic; age, 35...
December 2015: Journal of the American Heart Association
Otto A Smiseth, Hans Torp, Anders Opdahl, Kristina H Haugaa, Stig Urheim
Myocardial strain is a principle for quantification of left ventricular (LV) function which is now feasible with speckle-tracking echocardiography. The best evaluated strain parameter is global longitudinal strain (GLS) which is more sensitive than left ventricular ejection fraction (LVEF) as a measure of systolic function, and may be used to identify sub-clinical LV dysfunction in cardiomyopathies. Furthermore, GLS is recommended as routine measurement in patients undergoing chemotherapy to detect reduction in LV function prior to fall in LVEF...
April 14, 2016: European Heart Journal
Kristina H Haugaa, Trine F Haland, Ida S Leren, Jørg Saberniak, Thor Edvardsen
This review aims to give an update on the pathogenesis, clinical manifestations, and diagnosis of arrhythmogenic right ventricular cardiomyopathy (ARVC). Arrhythmogenic right ventricular cardiomyopathy is mainly an autosomal dominant inherited disease linked to mutations in genes encoding desmosomes or desmosome-related proteins. Classic symptoms include palpitations, cardiac syncope, and aborted cardiac arrest due to ventricular arrhythmias. Heart failure may develop in later stages. Diagnosis is based on the presence of major and minor criteria from the Task Force Criteria revised in 2010 (TFC 2010), which includes evaluation of findings from six different diagnostic categories...
July 2016: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
Ida S Leren, Jørg Saberniak, Eman Majid, Trine F Haland, Thor Edvardsen, Kristina H Haugaa
BACKGROUND: Catecholaminergic polymorphic ventricular tachycardia (CPVT) is an inheritable cardiac disease predisposing to malignant ventricular arrhythmias. OBJECTIVE: We aimed to explore the incidence and severity of ventricular arrhythmias in patients with CPVT before the initiation of β-blocker treatment, when treated with β1-selective β-blockers, and when treated with nadolol. METHODS: In this study, 34 patients with CPVT were included (mean age 34 ± 19 years; 15 (44%) women; 30 (88%) ryanodine receptor 2 variant positive)...
February 2016: Heart Rhythm: the Official Journal of the Heart Rhythm Society
Daniel D Joyce, J Martijn Bos, Kristina H Haugaa, Robert F Tarrell, Bruce W Morlan, Pedro J Caraballo, Michael J Ackerman
Patients undergoing surgery are often exposed to QT-inciting factors that may increase the risk for complications. We evaluated the clinical characteristics and outcomes of patients with QTc ≥500 ms within the first 24 hours after surgery as identified by an institution-wide electrocardiogram alert system. From November 2010 to June 2011, 470 patients exhibited an electrocardiographically isolated QTc ≥500 ms. QT prolongation after surgery was the setting for >1 of every 10 QTc alerts (59 patients). We determined the presence of QT prolonging medical conditions, drugs, electrolyte abnormalities, and the surgical patient's clinical outcome...
November 15, 2015: American Journal of Cardiology
Kristina H Haugaa, Henning Bundgaard, Thor Edvardsen, Ole Eschen, Thomas Gilljam, Jim Hansen, Henrik Kjærulf Jensen, Pyotr G Platonov, Anneli Svensson, Jesper H Svendsen
OBJECTIVES: Diagnostics of patients with arrhythmogenic right ventricular cardiomyopathy (ARVC) are complex, and based on the 2010 Task Force document including different diagnostic modalities. However, recommendations for clinical management and follow-up of patients with ARVC and their relatives are sparse. This paper aims to give a practical overview of management strategies, risk stratification, and selection of appropriate therapies for patients with ARVC and their family members...
2015: Scandinavian Cardiovascular Journal: SCJ
Bhupendar Tayal, John Gorcsan, Antonia Delgado-Montero, Josef J Marek, Kristina H Haugaa, Keiko Ryo, Akiko Goda, Niels Thue Olsen, Samir Saba, Niels Risum, Peter Sogaard
BACKGROUND: Tissue Doppler cross-correlation analysis has been shown to be associated with long-term survival after cardiac resynchronization defibrillator therapy (CRT-D). Its association with ventricular arrhythmia (VA) is unknown. METHODS: From two centers 151 CRT-D patients (New York Heart Association functional classes II-IV, ejection fraction ≤ 35%, and QRS duration ≥ 120 msec) were prospectively included. Tissue Doppler cross-correlation analysis of myocardial acceleration curves from the basal segments in the apical views both at baseline and 6 months after CRT-D implantation was performed...
December 2015: Journal of the American Society of Echocardiography
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