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https://www.readbyqxmd.com/read/28903949/intramuscular-tendon-involvement-on-mri-has-limited-value-for-predicting-time-to-return-to-play-following-acute-hamstring-injury
#1
Anne D van der Made, Emad Almusa, Rod Whiteley, Bruce Hamilton, Cristiano Eirale, Frank van Hellemondt, Johannes L Tol
BACKGROUND: Hamstring injury with intramuscular tendon involvement is regarded as a serious injury with a delay in return to play (RTP) of more than 50 days and reinjury rates up to 63%. However, this reputation is based on retrospective case series with high risk of bias. OBJECTIVE: Determine whether intramuscular tendon involvement is associated with delayed RTP and elevated rates of reinjury. METHODS: MRI of male athletes with an acute hamstring injury was obtained within 5 days of injury...
September 13, 2017: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/28869113/cold-induced-retrotransposition-of-fish-lines
#2
Shue Chen, Mengchao Yu, Xu Chu, Wenhao Li, Xiujuan Yin, Liangbiao Chen
Classes of retrotransposons constitute a large portion of metazoan genome. There have been cases reported that genomic abundance of retrotransposons is correlated with the severity of low environmental temperatures. However, the molecular mechanisms underlying such correlation are unknown. We show here by cell transfection assays that retrotransposition (RTP) of a long interspersed nuclear element (LINE) from an Antarctic notothenioid fish Dissostichus mawsoni (dmL1) could be activated by low temperature exposure, causing increased dmL1 copies in the host cell genome...
July 24, 2017: Journal of Genetics and Genomics, Yi Chuan Xue Bao
https://www.readbyqxmd.com/read/28865574/can-competitive-athletes-return-to-high-level-play-after-osteochondral-allograft-transplantation-of-the-knee
#3
Mark A McCarthy, Maximilian A Meyer, Alexander E Weber, David M Levy, Annemarie K Tilton, Adam B Yanke, Brian J Cole
PURPOSE: To investigate functional outcomes among competitive athletes undergoing osteochondral allograft (OCA) transplantation of the knee, including rates of return to play (RTP), and factors preventing RTP. METHODS: A retrospective review identified all competitive athletes (high school, intercollegiate, professional) undergoing isolated femoral condyle OCA from 2004 to 2013. Patient-reported outcome (PRO) questionnaires (Lysholm, International Knee Documentation Committee [IKDC], Knee Injury and Osteoarthritis Outcome Score [KOOS], Western Ontario and McMasters Universities Arthritis Index [WOMAC], 12-Item Short Form Health Survey [SF-12], Tegner, and Marx) and custom RTP surveys were administered...
September 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/28852473/evaluation-of-operating-room-reverse-trendelenburg-positioning-and-its-effect-on-postoperative-hypoxemia-aspiration-and-length-of-stay-a-retrospective-study-of-consecutive-patients
#4
C Michael Dunham, Barbara M Hileman, Amy E Hutchinson, Tamara Antonaccio, Elisha A Chance, Gregory S Huang, Gregory Szmaj, Kristen Calabro, Cynthia Bishop, Tyson T Schrickel
BACKGROUND: In 2014, this group published an investigation of surgical patients from 2012 who had substantial rates of postoperative hypoxemia (POH) and perioperative pulmonary aspiration (POPA). Therefore, we investigated whether intraoperative reverse Trendelenburg positioning (RTP) decreases POH and POPA rates. METHODS: Consecutive ASA I-IV surgical patients who had preoperative pulmonary stability requiring general anesthesia with endotracheal intubation were evaluated...
2017: Perioperative Medicine
https://www.readbyqxmd.com/read/28843373/prospective-clinical-implementation-of-a-novel-magnetic-resonance-tracking-device-for-real-time-brachytherapy-catheter-positioning
#5
Jose de Arcos, Ehud J Schmidt, Wei Wang, Junichi Tokuda, Kamal Vij, Ravi T Seethamraju, Antonio L Damato, Charles L Dumoulin, Robert A Cormack, Akila N Viswanathan
PURPOSE: We designed and built dedicated active magnetic resonance (MR)-tracked (MRTR) stylets. We explored the role of MRTR in a prospective clinical trial. METHODS AND MATERIALS: Eleven gynecologic cancer patients underwent MRTR to rapidly optimize interstitial catheter placement. MRTR catheter tip location and orientation were computed and overlaid on images displayed on in-room monitors at rates of 6 to 16 frames per second. Three modes of actively tracked navigation were analyzed: coarse navigation to the approximate region around the tumor; fine-tuning, bringing the stylets to the desired location; and pullback, with MRTR stylets rapidly withdrawn from within the catheters, providing catheter trajectories for radiation treatment planning (RTP)...
June 7, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28839132/neuroimaging-of-sport-concussion-persistent-alterations-in-brain-structure-and-function-at-medical-clearance
#6
Nathan W Churchill, Michael G Hutchison, Doug Richards, General Leung, Simon J Graham, Tom A Schweizer
The medical decision of return to play (RTP) after a sport concussion is largely based on symptom status following a graded exercise protocol. However, it is currently unknown how objective markers of brain structure and function relate to clinical recovery. The goal of this study was to determine whether differences in brain structure and function at acute injury remain present at RTP. In this longitudinal study, 54 active varsity athletes were scanned using magnetic resonance imaging (MRI), including 27 with recent concussion, imaged at both acute injury and medical clearance, along with 27 matched controls...
August 24, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28838286/self-reported-history-of-seizure-and-baseline-neurocognitive-test-performance-in-student-athletes-an-initial-investigation
#7
Brian H Zalneraitis, Alec J Pawlukiewicz, Aaron M Yengo-Kahn, Gary S Solomon
OBJECTIVES: Baseline neurocognitive assessment data can be critical in return to play (RTP) decision-making following a sport-related concussion (SRC). The literature indicates that many modifying factors of SRC have been studied empirically; however, there has been little investigation into the effect of a self-reported history of seizure(s) on baseline neurocognitive test data. The objective of this investigation was to determine whether a self-reported history of seizure(s) is associated with differences in baseline Immediate Post-Concussion Assessment and Cognitive Testing (ImPACT) performance...
August 25, 2017: Physician and Sportsmedicine
https://www.readbyqxmd.com/read/28825917/evaluation-of-an-automatic-mr-based-gold-fiducial-marker-localisation-method-for-mr-only-prostate-radiotherapy
#8
Matteo Maspero, Cornelis A T Van den Berg, Frank Zijlstra, Gonda G Sikkes, Hans C J de Boer, Gert J Meijer, Linda G W Kerkmeijer, Max A Viergever, Jan J W Lagendijk, Peter R Seevinck
An MR-only radiotherapy planning (RTP) workflow would reduce cost, radiation exposure and uncertainties introduced by CT-MRI registrations. In the case of prostate treatment, one of the remaining challenges currently withholding implementation of an RTP workflow is the MR-based localisation of intraprostatic gold Fiducial Markers (FMs), which is crucial for accurate patient positioning. Currently, MR-based FM localisation is clinically performed manually. This is sub-optimal as manual interaction increases workload...
August 21, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28771963/organic-nanocrystals-with-bright-red-persistent-room-temperature-phosphorescence-for-biological-applications
#9
S M Ali Fateminia, Zhu Mao, Shidang Xu, Zhiyong Yang, Zhenguo Chi, Bin Liu
Persistent room-temperature phosphorescence (RTP) in pure organic materials has attracted great attention because of their unique optical properties. The design of organic materials with bright red persistent RTP remains challenging. Herein, we report a new design strategy for realizing high brightness and long lifetime of red-emissive RTP molecules, which is based on introducing an alkoxy spacer between the hybrid units in the molecule. The spacer offers easy Br-H bond formation during crystallization, which also facilitates intermolecular electron coupling to favor persistent RTP...
August 3, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28770309/mri-detection-of-soleus-muscle-injuries-in-professional-football-players
#10
G Pezzotta, G Querques, A Pecorelli, R Nani, S Sironi
OBJECTIVES: To describe magnetic resonance imaging (MRI) characteristics of soleus muscle injuries in symptomatic professional football players stratified according to both the Munich consensus statement and the British Athletics Muscle Injury Classification (BAMIC), and to investigate the association between specific MRI features and the "return to play" (RTP). MATERIALS AND METHODS: Professional football players with an episode of acute posterior calf pain and impaired function, subsequent to sports activity, underwent ultrasound followed by MRI examination reviewed by two different radiologists with more than 10 years of experience in the musculoskeletal system...
August 2, 2017: Skeletal Radiology
https://www.readbyqxmd.com/read/28769016/favipiravir-t-705-a-broad-spectrum-inhibitor-of-viral-rna-polymerase
#11
Yousuke Furuta, Takashi Komeno, Takaaki Nakamura
Favipiravir (T-705; 6-fluoro-3-hydroxy-2-pyrazinecarboxamide) is an anti-viral agent that selectively and potently inhibits the RNA-dependent RNA polymerase (RdRp) of RNA viruses. Favipiravir was discovered through screening chemical library for anti-viral activity against the influenza virus by Toyama Chemical Co., Ltd. Favipiravir undergoes an intracellular phosphoribosylation to be an active form, favipiravir-RTP (favipiravir ribofuranosyl-5'-triphosphate), which is recognized as a substrate by RdRp, and inhibits the RNA polymerase activity...
2017: Proceedings of the Japan Academy. Series B, Physical and Biological Sciences
https://www.readbyqxmd.com/read/28727937/preoperative-short-form-health-survey-score-is-predictive-of-return-to-play-and-minimal-clinically-important-difference-at-a-minimum-2-year-follow-up-after-anterior-cruciate-ligament-reconstruction
#12
Benedict U Nwachukwu, Brenda Chang, Pramod B Voleti, Patricia Berkanish, Matthew R Cohn, David W Altchek, Answorth A Allen, Riley J Williams
BACKGROUND: There is increased interest in understanding the preoperative determinants of postoperative outcomes. Return to play (RTP) and the patient-reported minimal clinically important difference (MCID) are useful measures of postoperative outcomes after anterior cruciate ligament reconstruction (ACLR). PURPOSE: To define the MCID after ACLR and to investigate the role of preoperative outcome scores for predicting the MCID and RTP after ACLR. STUDY DESIGN: Case-control study; Level of evidence, 3...
July 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28685822/thalamic-connections-of-the-core-auditory-cortex-and-rostral-supratemporal-plane-in-the-macaque-monkey
#13
Brian H Scott, Kadharbatcha S Saleem, Yukiko Kikuchi, Makoto Fukushima, Mortimer Mishkin, Richard C Saunders
In the primate auditory cortex, information flows serially in the mediolateral dimension from core, to belt, to parabelt. In the caudorostral dimension, stepwise serial projections convey information through the primary, rostral, and rostrotemporal (AI, R, and RT) core areas on the supratemporal plane, continuing to the rostrotemporal polar area (RTp) and adjacent auditory-related areas of the rostral superior temporal gyrus (STGr) and temporal pole. In addition to this cascade of corticocortical connections, the auditory cortex receives parallel thalamocortical projections from the medial geniculate nucleus (MGN)...
July 7, 2017: Journal of Comparative Neurology
https://www.readbyqxmd.com/read/28658080/blood-pressure-response-during-resistance-training-of-different-work-to-rest-ratio
#14
Anderson Caetano Paulo, Valmor Tricoli, Andréia C C Queiroz, Gilberto Laurentino, Cláudia L M Forjaz
Changes in the work to rest ratio (W:R) of resistance training protocols (RTP) (i.e. decreasing work and/or increasing rest) reduce the marked elevation in blood pressure (BP) that occurs during RTP execution. However, whether changes in RTP protocol structure without changing W:R can change BP responses to RTP is unknown. To investigate the effect of different structures of rest intervals and number of repetitions per set on BP response among RTP equated and nonequated for W:R, 20 normotensive participants (25±4 years) performed four different RTP of the leg extension exercise with the same work but different W:R structures...
June 22, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28657778/successful-return-to-sport-after-arthroscopic-shoulder-stabilization-versus-nonoperative-management-in-contact-athletes-with-anterior-shoulder-instability-a-prospective-multicenter-study
#15
Jonathan F Dickens, John-Paul Rue, Kenneth L Cameron, John M Tokish, Karen Y Peck, C Dain Allred, Steven J Svoboda, Robert Sullivan, Kelly G Kilcoyne, Brett D Owens
BACKGROUND: The debate continues regarding the optimal treatment of intercollegiate contact athletes with in-season anterior shoulder instability. PURPOSE: To examine return to sport and recurrent instability in the season after the index in-season anterior instability event. STUDY DESIGN: Cohort study; Level of evidence, 2. METHODS: Forty-five contact intercollegiate athletes treated nonoperatively or with arthroscopic stabilization were prospectively followed in a multicenter observational study to evaluate return to play (RTP) and recurrent instability in the season after an initial in-season anterior glenohumeral instability event...
September 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28644678/professional-athletes-return-to-play-and-performance-after-operative-repair-of-an-achilles-tendon-rupture
#16
David P Trofa, J Chance Miller, Eugene S Jang, Denzel R Woode, Justin K Greisberg, J Turner Vosseller
BACKGROUND: Most Achilles tendon ruptures are sports related. However, few studies have examined and compared the effect of surgical repair for complete ruptures on return to play (RTP), play time, and performance across multiple sports. PURPOSE: To examine RTP and performance among professional athletes after Achilles tendon repair and compare pre- versus postoperative functional outcomes of professional athletes from different major leagues in the United States...
June 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28636566/detection-of-muscle-gap-by-l-bia-in-muscle-injuries-clinical-prognosis
#17
L Nescolarde, J Yanguas, J Terricabras, H Lukaski, X Alomar, J Rosell-Ferrer, G Rodas
Sport-related muscle injury classifications are based basically on imaging criteria such as ultrasound (US) and magnetic resonance imaging (MRI) without consensus because of a lack of clinical prognostics for return-to-play (RTP), which is conditioned upon the severity of the injury, and this in turn with the muscle gap (muscular fibers retraction). Recently, Futbol Club Barcelona's medical department proposed a new muscle injury classification in which muscle gap plays an important role, with the drawback that it is not always possible to identify by MRI...
June 21, 2017: Physiological Measurement
https://www.readbyqxmd.com/read/28586385/receptor-transporting-protein-rtp-family-members-play-divergent-roles-in-the-functional-expression-of-odorant-receptors
#18
Teng Yu, Xubo Su, Yi Pan, Hanyi Zhuang
Receptor transporting protein (RTP) family members, RTP1S and RTP2, are accessory proteins to mammalian odorant receptors (ORs). They are expressed in the olfactory sensory neurons and facilitate OR trafficking to the cell-surface membrane and ligand-induced responses in heterologous cells. We previously identified different domains in RTP1S that are important for different stages of OR trafficking, odorant-mediated responses, and interaction with ORs. However, the exact roles of RTP2 and the significance of the requirement of the seemingly redundant co-expression of the two RTP proteins in vivo have received less attention in the past...
2017: PloS One
https://www.readbyqxmd.com/read/28574869/cancer-incidence-estimation-method-an-apulian-experience
#19
Anna M Nannavecchia, Ivan Rashid, Francesco Cuccaro, Antonio Chieti, Danila Bruno, Maria G Burgio Lo Monaco, Cinzia Tanzarella, Lucia Bisceglia
The Cancer Registry of Puglia (RTP) was instituted in 2008 as a regional population-based cancer registry. It consists of six sections (Foggia, Barletta-Andria-Tran, Bari, Brindisi, Lecce, and Taranto) and covers more than 4 000 000 inhabitants. At present, four of six sections have received accreditation by AIRTUM (53% of regional population). To point out possible regional geographic variability in cancer incidence and also to support health services planning, we developed an original estimation method to ensure a complete territorial coverage...
September 2017: European Journal of Cancer Prevention
https://www.readbyqxmd.com/read/28557527/return-to-play-after-shoulder-instability-surgery-in-national-collegiate-athletic-association-division-i-intercollegiate-football-athletes
#20
R Judd Robins, Jimmy H Daruwalla, Seth C Gamradt, Eric C McCarty, Jason L Dragoo, Robert E Hancock, Jeffrey A Guy, George A Cotsonis, John W Xerogeanes, Jeffrey M Tuman, James E Tibone, Matthew A Javernick, Eric M Yochem, Stephanie A Boden, Alexis Pilato, Jennifer H Miley, Patrick E Greis
BACKGROUND: Recent attention has focused on the optimal surgical treatment for recurrent shoulder instability in young athletes. Collision athletes are at a higher risk for recurrent instability after surgery. PURPOSE: To evaluate variables affecting return-to-play (RTP) rates in Division I intercollegiate football athletes after shoulder instability surgery. STUDY DESIGN: Case series; Level of evidence, 4. METHODS: Invitations to participate were made to select sports medicine programs that care for athletes in Division I football conferences (Pac-12 Conference, Southeastern Conference [SEC], Atlantic Coast Conference [ACC])...
August 2017: American Journal of Sports Medicine
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