keyword
MENU ▼
Read by QxMD icon Read
search

MMT

keyword
https://www.readbyqxmd.com/read/28339019/occupational-exposure-to-mount-etna-s-basaltic-dust-assessment-of-mutagenic-and-cytotoxic-effects
#1
Caterina Ledda, Salvatore Cocuzza, Monica Salerno, Paola Senia, Serena Matera, Venerando Rapisarda, Carla Loreto
Basalt and volcanic ash are natural constituents of the ground surrounding volcanic areas such as Mount Etna. The dust may be daily inhaled by the general population as well as by several types of workers, such as construction workers. In this experiment, we analyzed the potential mutagenic and cytotoxic effects of the materials used in construction industry, excavated from Mt. Etna. Ground basalt (A), volcanic ash (B), mixed basalt and cement (C) and cement (D) were studied with Ames test, for mutagenic assessment and with MMT assay for cytotoxic evaluation...
March 24, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28329935/-a-cross-sectional-survey-of-receiving-no-methadone-maintenance-treatment-in-hiv-infected-injecting-drug-users-in-dehong-dai-and-jingpo-autonomous-prefecture-yunnan-province
#2
R H Tang, R H Ye, Y C Yang, S T Yao, J B Wang, R M Zhang, L F Luo, Z L Wu, Y C Long, M S Yin, N He, S Duan
Objective: To understand the current status of receiving no methadone maintenance treatment (MMT) and influencing factors in HIV infected injecting drug users (IDUs) in Dehong Dai and Jingpo autonomous prefectures, Yunnan province. Methods: Data of survival of IDUs with AIDS in Dehong were collected from " Chinese National Comprehensive HIV/AIDS and Care Information System" in December, 2014. Results: There were 987 IDUs who should receive MMT, the majority of them were males (94.6%, 934/987), aged 35-44 years (53...
March 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28327551/genomic-reprograming-analysis-of-the-mesothelial-to-mesenchymal-transition-identifies-biomarkers-in-peritoneal-dialysis-patients
#3
Vicente Ruiz-Carpio, Pilar Sandoval, Abelardo Aguilera, Patricia Albar-Vizcaíno, María Luisa Perez-Lozano, Guadalupe T González-Mateo, Adrián Acuña-Ruiz, Jesús García-Cantalejo, Pedro Botías, María Auxiliadora Bajo, Rafael Selgas, José Antonio Sánchez-Tomero, Jutta Passlick-Deetjen, Dorothea Piecha, Janine Büchel, Sonja Steppan, Manuel López-Cabrera
Peritoneal dialysis (PD) is an effective renal replacement therapy, but a significant proportion of patients suffer PD-related complications, which limit the treatment duration. Mesothelial-to-mesenchymal transition (MMT) contributes to the PD-related peritoneal dysfunction. We analyzed the genetic reprograming of MMT to identify new biomarkers that may be tested in PD-patients. Microarray analysis revealed a partial overlapping between MMT induced in vitro and ex vivo in effluent-derived mesothelial cells, and that MMT is mainly a repression process being higher the number of genes that are down-regulated than those that are induced...
March 22, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28325700/the-relationship-between-preoperative-needle-electromyography-findings-and-muscle-power-restoration-after-surgery-in-severe-carpal-tunnel-syndrome-patients
#4
Yuki Hara, Yasumasa Nishiura, Naoyuki Ochiai, Shinji Murai, Masashi Yamazaki
PURPOSE: Needle electromyography provides essential information about the functional aspects of the muscle. But little attention has been given in the literature to needle electromyography examinations in carpal tunnel syndrome. We examined the relationship between preoperative needle electromyography findings and functional recovery of the abductor pollicis brevis (APB) muscle in severe carpal tunnel syndrome patients. METHODS: The subjects of this study were 49 patients, 58 hands, who fit the following 5 criteria: (1) idiopathic carpal tunnel syndrome; (2) pre-op MMT grade of the APB muscle was M0 or M1; (3) APB-CMAP (compound muscle action potential) was not evoked in a median nerve conduction study; (4) needle electromyography of the APB muscle had been done; (5) underwent carpal tunnel release only...
March 18, 2017: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/28319665/synthesis-of-four-disulfide-insulin-analogs-via-sequential-disulfide-bond-formation
#5
Fangzhou Wu, John P Mayer, Vasily G Gelfanov, Fa Liu, Richard D DiMarchi
Naturally-occurring, multiple cysteine-containing peptides are a structurally unique class of compounds with a wide range of therapeutic and diagnostic applications. The development of reliable, and precise chemical methods for their preparation is of paramount importance to facilitate exploration of their utility. We report an efficient approach based on stepwise, sequentially directed disulfide bond formation, exemplified here by the synthesis of four-disulfide bond containing insulin analogs. The cysteine protections consisted of tert-butylthiol (StBu), thiol-trimethoxyphenyl (STmp), trityl (Trt), 4-methoxytrityl (Mmt), S-acetamidomethyl (Acm) and tert-butyl (tBu)...
March 20, 2017: Journal of Organic Chemistry
https://www.readbyqxmd.com/read/28314144/hydrophobicity-and-polymer-compatibility-of-poss-modified-wyoming-na-montmorillonite-for-developing-polymer-clay-nanocomposites
#6
Rustam Hojiyev, Yusuf Ulcay, Mirabbos Hojamberdiev, Mehmet S Çelik, William M Carty
The aim of the present work was to investigate the hydrophobicity and polymer compatibility of aminopropylisooctyl polyhedral oligomeric silsequioxane (POSS) - modified Na-montmorillonite (Na-MMT) towards developing polymer-clay nanocomposites. The effect of different concentrations of POSS on properties of Na-MMT was studied. The intercalation ability of the POSS molecules into the Na-MMT interlayer was analyzed by X-ray diffraction. It was found that the d001 value was increased with increasing the POSS concentration, indicating the successful intercalation of the POSS molecules into the Na-MMT interlayer...
July 1, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28289884/the-relative-contribution-of-genes-operating-in-the-s-methylmethionine-cycle-to-methionine-metabolism-in-arabidopsis-seeds
#7
Hagai Cohen, Asaf Salmon, Zipora Tietel, Yael Hacham, Rachel Amir
Enzymes operating in the S -methylmethionine cycle make a differential contribution to methionine synthesis in seeds. In addition, mutual effects exist between the S -methylmethionine cycle and the aspartate family pathway in seeds. Methionine, a sulfur-containing amino acid, is a key metabolite in plant cells. The previous lines of evidence proposed that the S-methylmethionine (SMM) cycle contributes to methionine synthesis in seeds where methionine that is produced in non-seed tissues is converted to SMM and then transported via the phloem into the seeds...
March 13, 2017: Plant Cell Reports
https://www.readbyqxmd.com/read/28286852/acute-myocardial-infarction-following-naltrexone-consumption-a-case-report
#8
Bita Dadpour, Arash Gholoobi, Shahrad Tajoddini, Amir Habibi
Cardiovascular effects of opioid withdrawal have long been studied. It was reported that patients with underlying ischemic heart disease and atherosclerotic vessels may be complicated by a sudden physical and emotional stress due to withdrawal syndrome. But some other believes sudden increase in catecholamine level as a sympathetic overflow might effect on heart with and without underlying ischemia. In the current study, a patient on methadone maintenance therapy (MMT) who experienced myocardial infarction (MI) after taking naltrexone was described...
2017: Emergency (Tehran, Iran)
https://www.readbyqxmd.com/read/28275446/evolution-of-the-health-sector-response-to-hiv-in-myanmar-progress-challenges-and-the-way-forward
#9
EDITORIAL
Htun Nyunt Oo, San Hone, Masami Fujita, Amaya Maw-Naing, Krittayawan Boonto, Marjolein Jacobs, Sabe Phyu, Phavady Bollen, Jacquie Cheung, Htin Aung, May Thu Aung Sang, Aye Myat Soe, Razia Pendse, Eamonn Murphy
Critical building blocks for the response to HIV were made until 2012 despite a series of political, social and financial challenges. A rapid increase of HIV service coverage was observed from 2012 to 2015 through collaborative efforts of government and non-governmental organisations (NGOs). Government facilities, in particular, demonstrated their capacity to expand services for antiretroviral therapy (ART), prevention of mother-to-child transmission (PMTCT) of HIV, tuberculosis and HIV co-infection and methadone-maintenance therapy (MMT)...
November 28, 2016: Journal of Virus Eradication
https://www.readbyqxmd.com/read/28254285/pre-dispersed-organo-montmorillonite-organo-mmt-nanofiller-morphology-cytocompatibility-and-impact-on-flexibility-toughness-and-biostability-of-biomedical-ethyl-vinyl-acetate-eva-copolymer
#10
Azlin F Osman, Tuty Fareyhynn M Fitri, Md Rakibuddin, Fatimah Hashim, Syed Ahmad Tajudin Tuan Johari, Rajakumar Ananthakrishnan, Rafiza Ramli
Polymer-clay based nanocomposites are among the attractive materials to be applied for various applications, including biomedical. The incorporation of the nano sized clay (nanoclay) into polymer matrices can result in their remarkable improvement in mechanical, thermal and barrier properties as long as the nanofillers are well exfoliated and dispersed throughout the matrix. In this work, exfoliation strategy through pre-dispersing process of the organically modified montmorillonite (organo-MMT) nanofiller was done to obtain ethyl vinyl acetate (EVA) nanocomposite with improved flexibility, toughness, thermal stability and biostability...
May 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28252574/abcb1-polymorphisms-and-cold-pressor-pain-responses-opioid-dependent-patients-on-methadone-maintenance-therapy
#11
Zalina Zahari, Chee Siong Lee, Muslih Abdulkarim Ibrahim, Nurfadhlina Musa, Mohd Azhar Mohd Yasin, Yeong Yeh Lee, Soo Choon Tan, Nasir Mohamad, Rusli Ismail
BACKGROUND: Methadone is a substrate of the P-glycoprotein efflux transporter, which is encoded by ABCB1 (MDR1), and thus, ABCB1 polymorphisms may influence the transport of methadone at the blood-brain barrier, affecting its adverse effects. OBJECTIVES: This study investigated the association between ABCB1 polymorphisms and cold pressor pain responses among opioid-dependent patients on methadone maintenance therapy (MMT). METHODS: Malay male opioid-dependent patients receiving MMT (n = 148) were recruited...
March 2017: Nursing Research
https://www.readbyqxmd.com/read/28252455/variation-in-the-viral-hepatitis-and-hiv-policies-and-practices-of-methadone-maintenance-programs
#12
Amy B Jessop, Jeffrey K Hom, Monika Burke
OBJECTIVE: Patients prescribed methadone maintenance treatment (MMT) demonstrate elevated prevalence of hepatitis B virus (HBV), hepatitis C virus, and HIV. Government agencies recommend testing for these infections in MMT programs, but uptake is limited. METHODS: We audited infection-related policies and practices of all 14 MMT programs in Philadelphia, Pennsylvania, in 2015. Results were tabulated and compared with the results from a 2010 audit of 10 of 12 MMT programs...
March 1, 2017: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/28247593/c-reactive-protein-symptoms-and-activity-of-daily-living-in-patients-with-advanced-cancer-receiving-palliative-care
#13
Koji Amano, Isseki Maeda, Tatsuya Morita, Mika Baba, Tomofumi Miura, Takashi Hama, Ichiro Mori, Nobuhisa Nakajima, Tomohiro Nishi, Hiroki Sakurai, Satofumi Shimoyama, Takuya Shinjo, Hiroto Shirayama, Takeshi Yamada, Shigeki Ono, Taketoshi Ozawa, Ryo Yamamoto, Naoki Yamamoto, Hideki Shishido, Hiroya Kinoshita
BACKGROUND: The association between C-reactive protein (CRP) level, symptoms, and activities of daily living (ADL) in advanced cancer patients is unclear. METHODS: Secondary data analysis of a multicenter prospective cohort study consisted of 2426 advanced cancer patients referred to palliative care settings was conducted to examine the cross-sectional relationships between CRP level, symptoms, and ADL disabilities. Laboratory data, symptoms, ADL, and manual muscle testing (MMT) results were obtained at baseline...
March 1, 2017: Journal of Cachexia, Sarcopenia and Muscle
https://www.readbyqxmd.com/read/28247413/mesothelial-to-mesenchymal-transition-as-a-possible-therapeutic-target-in-peritoneal-metastasis-of-ovarian-cancer
#14
Angela Rynne-Vidal, Chi Lam Au-Yeung, José A Jiménez-Heffernan, María Luisa Pérez-Lozano, Lucía Cremades-Jimeno, Carmen Bárcena, Ignacio Cristóbal-García, Concepción Fernández-Chacón, Tsz Lun Yeung, Samuel C Mok, Pilar Sandoval, Manuel López-Cabrera
Peritoneal dissemination is the primary metastatic route of ovarian cancer (OvCa), often accompanied by accumulation of ascitic fluid. The peritoneal cavity is lined by mesothelial cells (MCs), which can convert into carcinoma-associated fibroblasts (CAFs) through mesothelial-to-mesenchymal transition (MMT). Here, we demonstrate that MCs isolated from ascitic fluid (AFMCs) of OvCa patients with peritoneal implants also undergo MMT and promote subcutaneous tumour growth in mice. RNA sequencing of AFMCs revealed that MMT-related pathways-including TGF-β signalling-are differentially regulated, and a gene signature was verified in peritoneal implants from OvCa patients...
March 1, 2017: Journal of Pathology
https://www.readbyqxmd.com/read/28238465/factors-related-to-client-satisfaction-with-methadone-maintenance-treatment-in-china
#15
Li Li, W Scott Comulada, Chunqing Lin, Julie Hsieh, Sitong Luo, Zunyou Wu
BACKGROUND: This study examined clients' treatment satisfaction with the services provided by methadone maintenance treatment (MMT) in China and explored relevant factors that are directly or indirectly associated with treatment satisfaction. METHODS: The study used baseline data from a randomized controlled trial conducted among 2,448 clients from 68 MMT clinics in five provinces of China. The participants reported their demographic characteristics, treatment-related factors, depressive symptoms, treatment progression, counseling rapport, and treatment satisfaction...
February 23, 2017: Journal of Substance Abuse Treatment
https://www.readbyqxmd.com/read/28235379/the-oxygen-reduction-electrocatalytic-activity-of-cobalt-and-nitrogen-co-doped-carbon-nanocatalyst-synthesized-by-a-flat-template
#16
Chaozhong Guo, Youcheng Wu, Zhongbin Li, Wenli Liao, Lingtao Sun, Chao Wang, Bixia Wen, Yanrong Li, Changguo Chen
The design of noble-metal-free catalysts for oxygen reduction reaction (ORR) is very important to the commercialization of fuel cells. Here, we use a Co-modified montmorillonite (Co-MMT) as a flat template to prepare Co- and N-doped nanocarbon ORR catalysts derived from carbonization of polyaniline at controlled temperatures. The use of flat template can hinder the agglomeration of polyaniline during pyrolysis process and optimize the N-rich active site density on the surface. The addition of transition metal Co in the flat MMT template can largely promote the formation of Co-N sites in prepared catalyst, facilitating the effective improvement of catalytic activity towards the ORR with a direct four-electron transfer pathway...
December 2017: Nanoscale Research Letters
https://www.readbyqxmd.com/read/28231430/combined-high-stretchability-and-gas-barrier-in-hydrogen-bonded-multilayer-nanobrick-wall-thin-films
#17
Shuang Qin, Yixuan Song, Michael E Floto, Jaime C Grunlan
Hydrogen-bonded multilayer thin films are very stretchable, but their gas barrier properties are modest compared to more traditional ionically bonded assemblies. In an effort to improve the gas barrier of poly(ethylene oxide) (PEO)-poly(acrylic acid) (PAA) multilayer films without sacrificing stretchability, montmorillonite (MMT) clay platelets were combined with PAA and alternately deposited with PEO. A ten-bilayer PEO/PAA+MMT film (432 nm thick), deposited on a 1 mm PU substrate, resulted in a 54× reduction in oxygen transmission rate after exposure to a 20% strain...
February 27, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28216092/health-care-professionals-perceptions-of-a-community-based-virtual-ward-medicines-management-service-a-qualitative-study
#18
Andrew Kirkcaldy, Barbara A Jack, Louise C Cope
This article describes a qualitative research study using focus groups to explore the views and experiences of a medicines management team (MMT) on the service they deliver within a 'Virtual Ward' (VW); and those of the wider multidisciplinary team of healthcare professionals on the service provided by the MMT. Several themes emerged from the focus groups, including impact on patients and carers, team working and issues and challenges. A dedicated MMT was seen as a positive contribution to the VW, which potentially increased the quality of patient care, and appeared to be a positive experience for both the MM and wider multidisciplinary team...
February 3, 2017: Research in Social & Administrative Pharmacy: RSAP
https://www.readbyqxmd.com/read/28212645/retrospective-analysis-of-antiretroviral-therapy-uptake-and-retention-of-male-clients-receiving-methadone-maintenance-therapy-in-two-provinces-in-vietnam-potential-synergy-of-the-two-therapies
#19
Linh Thi Thuy Pham, Akiko Kitamura, Hoa Mai Do, Kim Anh Lai, Nhan Tuan Le, Van Thi Thuy Nguyen, Masaya Kato
BACKGROUND: Vietnam has a concentrated HIV epidemic with injection drug use being the dominant mode of HIV transmission. Vietnam has rapidly expanded antiretroviral therapy (ART) and methadone maintenance therapy (MMT). This study aims to analyze ART uptake and retention among male clients receiving MMT in Vietnam in the early phase of the MMT program. METHODS: The male clients (age ≥18) who were newly enrolled in care or started ART at two HIV clinics in Hanoi (2009 to 2011) and three HIV clinics in Can Tho (2010 to 2012) were included for the analysis...
February 17, 2017: Harm Reduction Journal
https://www.readbyqxmd.com/read/28211299/comparison-of-biodistribution-profile-of-monoclonal-antibodies-nanoparticles-and-aptamers-in-rats-with-breast-cancer
#20
COMPARATIVE STUDY
Cristal Cerqueira-Coutinho, Sotiris Missailidis, Jéssica Alessandra-Perini, Daniel Escorsim Machado, Jamila Alessandra Perini, Ralph Santos-Oliveira
The use of monoclonal antibodies and aptamers is growing every single day, as the use of nanoparticle systems. Although most of the products are under investigation, there are a few commercialized products available at the market, for human consume. In this study, we have compared three formulations (aptamer anti-MUC1, monoclonal antibody - Trastuzumab and monoclonal antibodies nanoparticles - PLA/PVA/MMT trastuzumab) to identify their profile as also to understand their behavior into an alive biological system...
May 2017: Artificial Cells, Nanomedicine, and Biotechnology
keyword
keyword
86678
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"