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Takashi Shiono, Kenichiro Yamamoto, Yuko Yotsumoto, Aruto Yoshida
The growth in health-conscious consumers continues to drive the demand for a wide variety of decaffeinated beverages. We previously developed a new technology using montmorillonite (MMT) in selective decaffeination of tea extract. This study evaluated and compared decaffeination of coffee extract using MMT and activated carbon (AC). MMT adsorbed caffeine without significant adsorption of caffeoylquinic acids (CQAs), feruloylquinic acids (FQAs), dicaffeoylquinic acids (di-CQAs), or caffeoylquinic lactones (CQLs)...
June 16, 2017: Bioscience, Biotechnology, and Biochemistry
Carol Strike, Miroslav Miskovic
In this commentary, we argue that the use of amendments to bylaws by Ontario cities and municipalities to restrict where and how methadone maintenance treatment (MMT) clinics and pharmacies operate may run counter to efforts to prevent record high rates of opioid-related overdoses. As the province of Ontario seeks to reform the opioid treatment system, it is crucial to understand the structural (e.g., stigma) and treatment system organization factors that drive the actions of municipalities such as those described above...
June 16, 2017: Canadian Journal of Public Health. Revue Canadienne de Santé Publique
Odelia Elkana, Miriam Adelson, Glen M Doniger, Anat Sason, Einat Peles
OBJECTIVES: To confirm our previous findings of less cognitive impairments (based on cognitive screening tools) among Methadone Maintenance Treatment (MMT) patients who achieved take-home dose (THD) privileges. METHODS: a random sample of 65 Israeli MMT patients were studied using computerized, age and education standardized, cognitive domains (attention, executive function, memory, motor skills), and non-computerized phonetic and semantic verbal fluency. Cognitive scores were within ±1 standard deviation (SD) of average for most domains, including non-verbal IQ, attention and motor skills...
June 14, 2017: World Journal of Biological Psychiatry
Xing Su, Suntharavathanan Mahalingam, Mohan Edirisinghe, Biqiong Chen
Highly stretchable and highly resilient polymer-clay nanocomposite hydrogels were synthesized by in situ polymerization of acrylamide in the presence of pristine montmorillonite (MMT) or chitosan-treated MMT nanoplatelets at an elevated temperature. Both nanocomposite hydrogels can be stretched to a strain of no less than 1290%. The treatment of clay with chitosan improves the tensile strength, elongation at break and energy at break of the nanocomposite hydrogel by 237%, 102% and 389%, respectively, due to the strong chitosan-MMT electrostatic interaction and grafting polyacrylamide onto chitosan chains...
June 13, 2017: ACS Applied Materials & Interfaces
Nadeesh Madusanka, Sai G Shivareddy, Mark D Eddleston, Pritesh Hiralal, Rachel A Oliver, Gehan A J Amaratunga
A dielectric nanocomposite based oncyanoethylatedcellulose (CRS) and MMT nanoclay was successfully prepared with different weight percentages (5%, 10% and 15%) of MMT. MMT nanoplatets obtained via sonication of MMT nanoclay in acetone for a prolonged period was used in the preparation of CRS-MMT nanocomposites. CRS-MMT thin films on SiO2/Si wafers are used to form metal-insulator-metal (MIM) type capacitors. At 1kHz CRS-MMT nanocomposites exhibited high dielectric constants (εr) of 71, 55 and 42 with low leakage current densities (10(-6)-10(-7)A/cm(2)) for nanocomposites with 5%, 10% and 15% weight of MMT respectively, higher than values of pure CRS (21), Na-MMT(10)...
September 15, 2017: Carbohydrate Polymers
Deborah Backus, Blake Burdett, Laura Hawkins, Christine Manella, Kevin K McCully, Mark Sweatman
BACKGROUND: Exercise is safe and beneficial for people with multiple sclerosis (MS). Functional electrical stimulation (FES) cycling offers people with significant weakness and mobility challenges an option for exercise. We sought to evaluate the safety of FES cycling and its potential to improve fatigue, pain, spasticity, and quality of life in people with moderate-to-severe MS. METHODS: Sixteen participants with MS who were nonambulatory cycled for 30 minutes two to three times a week for 1 month...
May 2017: International Journal of MS Care
Ana Sousa, Fábio Santos, Maria Manuela Gaspar, Susana Calado, João D Pereira, Eduarda Mendes, Ana Paula Francisco, Maria Jesus Perry
Metastatic melanoma still remains one the most difficult cancers to overcome. The aim of our research was the design of anti-tumour triazene compounds 3 for application to a melanoma-specific therapy. The strategy exploits the unique enzyme pathway of melanin biosynthesis for conversion of non-toxic prodrugs into toxic drugs in the melanoma cell. The compounds 3 were designed by coupling two active moieties, the alkylating triazenes and different tyrosinase substrates. All compounds 3 revealed to be chemically stable in isotonic phosphate buffer (PBS) at physiologic pH (t½≥48h), and most of them showed to be slowly hydrolysed in human plasma (1...
May 31, 2017: Bioorganic & Medicinal Chemistry
Yoshiki Kuwahara, Takuma Yuri, Hiromi Fujii, Yoshiro Kiyoshige
PURPOSE: Although recent morphological studies have revealed that the infraspinatus muscle is subdivided, the functions of the subregions remain unknown. The aim of this study is to investigate the functions of the infraspinatus subregions during lateral rotation using real-time tissue elastography (RTE). METHODS: Ten young male volunteers participated in the study. In addition to the infraspinatus subregions, the teres minor and two of six subregions of the supraspinatus determined by Kim were examined...
June 9, 2017: Surgical and Radiologic Anatomy: SRA
Long Hoang Nguyen, Huong Thu Thi Nguyen, Huong Lan Thi Nguyen, Bach Xuan Tran, Carl A Latkin
BACKGROUND: Medication adherence is essential to achieve successful methadone maintenance treatment (MMT). However, treatment adherence among MMT patients in the mountainous setting in Vietnam has not been yet investigated. This study aimed to explore the medication adherence and associated factors in MMT patients in Tuyen Quang, a mountainous province. METHODS: A cross-sectional survey was conducted in two MMT clinics namely Tuyen Quang and Son Duong. Convenience sampling method was used to recruit patients...
June 8, 2017: Substance Abuse Treatment, Prevention, and Policy
Zu-Xiang Peng, Xiao-Rong Zhong, Zhu Wang, Yu Wang, Yan-Ping Wang, Hong Zheng, Jing Jing
OBJECTIVES: To determine factors associated with the survival of patients with metastatic recurrent triple-negative breast cancer (mrTNBC). METHODS: Initial metastatic recurrent (during or after therapy) patients with triple-negative breast cancer (TNBC) confirmed by post-operate pathology in the West China Hospital of Sichuan University were followed up. The accumulative survival rates after recurrence were calculated using Kaplan-Meier method and differences were tested using log-rank tests...
July 2016: Sichuan da Xue Xue Bao. Yi Xue Ban, Journal of Sichuan University. Medical Science Edition
Stefanie Ehrbar, Alexander Jöhl, Adrianna Tartas, Luisa Sabrina Stark, Oliver Riesterer, Stephan Klöck, Matthias Guckenberger, Stephanie Tanadini-Lang
PURPOSE: Respiratory motion-management techniques (MMT) aim to ensure tumor dose coverage while sparing lung tissue. Dynamic treatment-couch tracking of the moving tumor is a promising new MMT and was compared to the internal-target-volume (ITV) concept, the mid-ventilation (MidV) principle and the gating approach in a planning study based on 4D dose calculations. METHODS: For twenty patients with lung lesions, planning target volumes (PTV) were adapted to the MMT and stereotactic body radiotherapy treatments were prepared with the 65%-isodose enclosing the PTV...
June 3, 2017: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
Aseel Issa, Salam A Ibrahim, Reza Tahergorabi
Salmonella Typhimurium (S. Typhi) and Escherichia coli (E. coli) have been responsible for an increasing number of outbreaks linked to fresh produce, such as baby spinach leaves, in the last two decades. More recently, antimicrobial biodegradable packaging systems have been attracting much attention in the food packaging industry as eco-friendly alternatives to conventional plastic packaging. The objective of this study was to evaluate the effect of antibacterial nanocomposite films on inoculated spinach leaves and on the sensory properties of these leaves during eight days of refrigerated storage...
June 3, 2017: Foods (Basel, Switzerland)
Kaina Zhou, Duolao Wang, Hengxin Li, Xiaoli Wei, Juan Yin, Peifeng Liang, Lingling Kou, Mengmeng Hao, Lijuan You, Xiaomei Li, Guihua Zhuang
This study aimed to explore the bidirectional relationships between retention and health-related quality of life (HRQoL) in patients from mainland China receiving methadone maintenance treatment (MMT). This prospective cohort study recruited 1,212 eligible MMT patients from the two largest MMT clinics (one privately and another publicly funded) in Xi'an. This study started in March 2012 with a 2-year follow-up until March 2014. Retention was assessed by repeated terminations, past treatment duration, premature terminations, and follow-up treatment duration...
2017: PloS One
Tea Rosic, Leen Naji, Monica Bawor, Brittany B Dennis, Carolyn Plater, David C Marsh, Lehana Thabane, Zainab Samaan
OBJECTIVE: There is a significant interindividual variability in treatment outcomes in methadone maintenance treatment (MMT) for opioid use disorder (OUD). This prospective cohort study examines the impact of comorbid psychiatric disorders on continued illicit opioid use in patients receiving MMT for OUD. METHODS: Data were collected from 935 patients receiving MMT in outpatient clinics between June 2011 and June 2015. Using linear regression analysis, we evaluated the impact of having a comorbid psychiatric disorder on continued illicit opioid use during MMT, adjusting for important confounders...
2017: Neuropsychiatric Disease and Treatment
Miriam Adelson, Shirley Linzy, Einat Peles
To compare in methadone maintenance treatment (MMT) gender characteristics and outcomes, all patients ever admitted to Tel Aviv (TA) MMT clinic (N = 837) (June 1993-December 2014) and Las Vegas (LV) MMT clinic (N = 1256) (February 2000-June 2015) were prospectively followed-up (until June 2016). Drugs in urine on admission and after one year and long-term retention up to 23 and 16 years, respectively, were analyzed. Females in both clinics admitted younger than males and following shorter duration of opioid usage (TA: n = 215, 25...
June 2, 2017: Substance Use & Misuse
Ayman M Atta, Ashraf M El-Saeed, Hamad A Al-Lohedan, Mohamed Wahby
Montmorillonite (MMT) clay mineral is widely used as filler for several organic coatings. Its activity is increased by exfoliation via chemical modification to produce nanomaterials. In the present work, the modification of MMT to form nanogel composites is proposed to increase the dispersion of MMT into epoxy matrices used to fill cracks and holes produced by the curing exotherms of epoxy resins. The dispersion of MMT in epoxy improved both the mechanical and anti-corrosion performance of epoxy coatings in aggressive marine environments...
June 2, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
Xianming Zheng, Junfeng Dou, Jing Yuan, Wei Qin, Xiaoxi Hong, Aizhong Ding
To remove cesium ions from water and soil, a novel adsorbent was synthesized by following a one-step co-precipitation method and using non-toxic raw materials. By combining ammonium-pillared montmorillonite (MMT) and magnetic nanoparticles (Fe3O4), an MMT/Fe3O4 composite was prepared and characterized. The adsorbent exhibited high selectivity of Cs(+) and could be rapidly separated from the mixed solution under an external magnetic field. Above all, the adsorbent had high removal efficiency in cesium-contaminated samples (water and soil) and also showed good recycling performance, indicating that the MMT/Fe3O4 composite could be widely applied to the remediation of cesium-contaminated environments...
June 2017: Journal of Environmental Sciences (China)
Jamey J Lister, Mark K Greenwald, David M Ledgerwood
Drug use during methadone induction/stabilization negatively influences later methadone-maintenance-treatment [MMT] outcomes (retention, abstinence). Our study examined the association of baseline risk factors to drug use during the first month of methadone treatment as well as longer-term treatment retention. We conducted these analyses among a race/ethnic minority group at high risk for worse MMT outcomes. African-American MMT patients (N=212) were interviewed at intake to assess clinical (drug use history), psychosocial (close family member substance abuse, psychosocial problems), and demographic factors...
July 2017: Journal of Substance Abuse Treatment
Luc Mercereau, Nicolas Todd, Gregoire Rey, Alain-Jacques Valleron
The daily temperature-mortality relationship is typically U shaped. The temperature of minimum mortality (MMT) has been shown to vary in space (higher at lower latitudes) and time (higher in recent periods). This indicates human populations adapt to their local environment. The pace of this adaptation is unknown. The objective of this study was to investigate the differences in the temperature-mortality relationship in continental France between foreign born and natives. Source data were the 5,273,005 death certificates of individuals living in continental France between 2000 and 2009 at the time of their death...
May 25, 2017: International Journal of Biometeorology
Saliha Memiş, Fatih Tornuk, Fatih Bozkurt, M Zeki Durak
In the present work, fenugreek seed gum (FSG)/clay nanocomposite films were prepared with nanoclays (Na(+) montmorillonite [MMT], halloysite [HNT] and Nanomer(®) I.44 P [NM]) at different amounts (0, 2.5, 5.0 and 7.5g clay/100g FSG) by solution casting method and characterized. Increasing amount of nanoclay significantly (P<0.05) improved oxygen barrier and thermal properties of the biodegradable films. Agar diffusion tests revealed that FSG based nanocomposite films exhibited strong antimicrobial properties against foodborne pathogens namely Listeria monocytogenes, Escherichia coli O157:H7, Staphylococcus aureus and Bacillus cereus independently of clay type and concentration...
May 20, 2017: International Journal of Biological Macromolecules
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