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https://www.readbyqxmd.com/read/28432986/the-effects-of-thymoquinone-on-hippocampal-cytokine-level-brain-oxidative-stress-status-and-memory-deficits-induced-by-lipopolysaccharide-in-rats
#1
Rahimeh Bargi, Fereshteh Asgharzadeh, Farimah Beheshti, Mahmoud Hosseini, Hamid Reza Sadeghnia, Majid Khazaei
OBJECTIVE: The study objective was to determine the protective effects of thymoquinone (TQ) on brain tissues oxidative stress status, hippocampal cytokine level, and learning and memory deficits induced by lipopolysaccharide (LPS) in rats. METHODS: Animals were randomly divided into the following groups and treated: (1) Control (saline), (2) LPS (1mg/kg i.p.), (3-5) 2, 5 or 10mg/kg TQ extract 30min before LPS injection. The treatment was started since two weeks before the behavioral experiments and continued during the behavioral tests (LPS injected 2h before each behavioral experiment)...
April 19, 2017: Cytokine
https://www.readbyqxmd.com/read/28432881/improvement-in-cadmium-tolerance-of-edible-rape-brassica-rapa-l-with-exogenous-application-of-chitooligosaccharide
#2
Haiying Zong, Kecheng Li, Song Liu, Lin Song, Ronge Xing, Xiaolin Chen, Pengcheng Li
Cadmium (Cd) is one of the most toxic heavy metals, which is readily taken up by plant roots and has deleterious effects on crop yield and quality. The study investigated the potential cross-protection roles of chitooligosaccharide (COS) in alleviating Cd toxicity in edible rape (Brassica rapa L.) under greenhouse conditions. The results demonstrated that spraying COS onto the leaves of edible rape could promote the plant growth and leaf chlorophyll contents, decrease the malondialdehyde (MDA) level in leaves as well as the Cd(2+) concentration in shoots and roots of edible rape under Cd stress...
April 7, 2017: Chemosphere
https://www.readbyqxmd.com/read/28432797/effects-of-levothyroxine-administration-and-withdrawal-on-the-hypothalamic-pituitary-thyroid-axis-in-euthyroid-dogs
#3
V Ziglioli, D L Panciera, G C Troy, W E Monroe, K M Boes, K R Refsal
BACKGROUND: Chronic supplementation can suppress the hypothalamic-pituitary-thyroid axis (HPTA) and make it difficult to assess thyroid function after withdrawal of levothyroxine. OBJECTIVES: To determine whether the HPTA is suppressed after levothyroxine administration in euthyroid dogs and the time required for resolution of any suppression. ANIMALS: Twenty-eight healthy euthyroid dogs. METHODS: A prospective, randomized study administering levothyroxine to euthyroid dogs for 8 weeks (group 1) or 16 weeks (group 2)...
April 22, 2017: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/28432545/genome-edited-animals-learning-from-gm-crops
#4
Ann Bruce
Genome editing of livestock is poised to become commercial reality, yet questions remain as to appropriate regulation, potential impact on the industry sector and public acceptability of products. This paper looks at how genome editing of livestock has attempted to learn some of the lessons from commercialisation of GM crops, and takes a systemic approach to explore some of the complexity and ambiguity in incorporating genome edited animals in a food production system. Current applications of genome editing are considered, viewed from the perspective of past technological applications...
April 21, 2017: Transgenic Research
https://www.readbyqxmd.com/read/28432495/investigating-emotional-contagion-in-dogs-canis-familiaris-to-emotional-sounds-of-humans-and-conspecifics
#5
Annika Huber, Anjuli L A Barber, Tamás Faragó, Corsin A Müller, Ludwig Huber
Emotional contagion, a basic component of empathy defined as emotional state-matching between individuals, has previously been shown in dogs even upon solely hearing negative emotional sounds of humans or conspecifics. The current investigation further sheds light on this phenomenon by directly contrasting emotional sounds of both species (humans and dogs) as well as opposed valences (positive and negative) to gain insights into intra- and interspecies empathy as well as differences between positively and negatively valenced sounds...
April 21, 2017: Animal Cognition
https://www.readbyqxmd.com/read/28432479/pharmacokinetics-and-efficacy-of-an-ivermectin-implant-for-long-term-prevention-of-dirofilaria-immitis-infection-in-dogs
#6
Marco Genchi, Anne Geneteau, Patrick Forget, Romain Delcombel, Claudio Genchi
An exploratory study was carried out to assess the in vivo efficacy of different prototypes of subcutaneous implants containing ivermectin (IVM) for the prevention of canine Dirofilaria immitis infection. The implants consisted of an ethylcellulose matrix containing IVM (3.0, 4.5, and 6.0 mg/implant; from 0.29 to 0.63 mg/kg bw) as active ingredient designed to release approximately 0.1 ng of IVM/mL in the plasma for at least 12 months. Six dogs were implanted on day -365. On day -12, three heartworm-free dogs were included in the study as a control group...
April 22, 2017: Parasitology Research
https://www.readbyqxmd.com/read/28432327/genotyping-brucella-canis-isolates-using-a-highly-discriminatory-multilocus-variable-number-tandem-repeat-analysis-mlva-assay
#7
Yi Yang, Yin Wang, Elizabeth Poulsen, Russell Ransburgh, Xuming Liu, Baoyan An, Nanyan Lu, Gary Anderson, Chengming Wang, Jianfa Bai
Differentiation of Brucella canis from other Brucella species are mainly performed through PCR-based methods and multilocus variable-number tandem-repeat (VNTR) analysis (MLVA) procedures. Both PCR-based and MLVA methods are limited in discriminating B. canis strains. A new MLVA-13Bc method for B. canis genotyping was established by combining eight newly-developed VNTRs with five published ones. During 2010 and 2016, 377 B. canis PCR-positives were identified from 6,844 canine blood samples from 22 U.S. states, resulting in 229 B...
April 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28432253/ten-minute-chat
#8
Melissa Kelson
Melissa Kelson is a fourth year student at the Royal Veterinary College. She recently spent a week of her EMS with the BVA's journals.
April 22, 2017: Veterinary Record
https://www.readbyqxmd.com/read/28432248/selected-highlights-from-other-veterinary-journals
#9
(no author information available yet)
No abstract text is available yet for this article.
April 22, 2017: Veterinary Record
https://www.readbyqxmd.com/read/28432246/celebrating-veterinary-excellence
#10
(no author information available yet)
No abstract text is available yet for this article.
April 22, 2017: Veterinary Record
https://www.readbyqxmd.com/read/28432245/two-bristol-students-win-feline-elective-prizes
#11
(no author information available yet)
No abstract text is available yet for this article.
April 22, 2017: Veterinary Record
https://www.readbyqxmd.com/read/28432244/taking-a-proactive-role-in-tackling-hereditary-disease-in-dogs
#12
(no author information available yet)
No abstract text is available yet for this article.
April 22, 2017: Veterinary Record
https://www.readbyqxmd.com/read/28432234/campaign-group-issues-public-reminder-that-dogs-die-in-hot-cars
#13
(no author information available yet)
No abstract text is available yet for this article.
April 22, 2017: Veterinary Record
https://www.readbyqxmd.com/read/28432229/50-years-on-time-for-a-fresh-look-at-the-veterinary-surgeons-act
#14
(no author information available yet)
No abstract text is available yet for this article.
April 22, 2017: Veterinary Record
https://www.readbyqxmd.com/read/28432013/design-of-multielectrode-arrays-for-uniform-sampling-of-different-orientations-of-tuned-unit-populations-in-the-cat-visual-cortex
#15
Yoshiko Maruyama, Hiroyuki Ito
For better reconstruction of stimulus orientation from a single trial activity of the neuron population in the visual cortex, we need uniform samplings of differently oriented tuned neurons. We recorded multiple neurons simultaneously by using either a four-tetrode array or an eight-microelectrode array, and examined what kinds of electrodes and layouts provided a more homogeneous distribution of the units' optimal orientations. The unit population sampled by a four-tetrode array showed more homogeneous distribution than those sampled by an eight-microelectrode array...
April 18, 2017: Neuroscience Research
https://www.readbyqxmd.com/read/28431930/quantitative-proteomics-reveals-key-proteins-regulated-by-eicosapentaenoic-acid-in-endothelial-activation
#16
Lu Zhang, Kunhong Xiao, Xuyang Zhao, Xiaoli Sun, Jianshu Zhang, Xian Wang, Yi Zhu, Xu Zhang
Eicosapentaenoic acid (EPA), an n-3 polyunsaturated fatty acid (PUFA), has been shown to decrease the risk of atherosclerosis by attenuating endothelial activation. In this study, we used mass spectrometry-based label-free quantitative proteomics to study the protective mechanisms of EPA and to identify key proteins that regulated by EPA in endothelial activation. Arachidonic acid (AA) was used as a control. HUVECs were pretreated with each of the two PUFAs, and then stimulated with TNFα as a model of endothelial activation...
April 18, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/28431577/dichloroacetic-acid-induced-testicular-toxicity-in-male-rats-and-the-protective-effect-of-date-fruit-extract
#17
Amira El Arem, Lamia Lahouar, Emna Behija Saafi, Amira Thouri, Fatma Ghrairi, Zohra Houas, Fadoua Neffati, Lotfi Achour
BACKGROUND: The present study was designed to investigate the protective effect of aqueous date extract (ADE) against the dichloroacetic acid (DCA)-induced testicular injury in rats. METHODS: Forty-eight male Wistar rats were randomly divided into six groups of eight: group I served as the control; group II was given ADE (4 ml/kg) by gavage; groups III and IV received DCA at 0.5 and 2 g/L drinking water, respectively; and groups V and VI received DCA at 0.5 and 2 g/L drinking water, respectively, before ADE administration...
April 22, 2017: BMC Pharmacology & Toxicology
https://www.readbyqxmd.com/read/28431528/diagnostic-performance-of-the-urinary-canine-calgranulins-in-dogs-with-lower-urinary-or-urogenital-tract-carcinoma
#18
Romy M Heilmann, Elizabeth A McNiel, Niels Grützner, David J Lanerie, Jan S Suchodolski, Jörg M Steiner
BACKGROUND: Onset of canine transitional cell carcinoma (TCC) and prostatic carcinoma (PCA) is usually insidious with dogs presenting at an advanced stage of the disease. A biomarker that can facilitate early detection of TCC/PCA and improve patient survival would be useful. S100A8/A9 (calgranulin A/B or calprotectin) and S100A12 (calgranulin C) are expressed by cells of the innate immune system and are associated with several inflammatory disorders. S100A8/A9 is also expressed by epithelial cells after malignant transformation and is involved in the regulation of cell proliferation and metastasis...
April 21, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28431524/biosecurity-survey-in-relation-to-the-risk-of-hpai-outbreaks-in-backyard-poultry-holdings-in-thimphu-city-area-bhutan
#19
Tenzin Tenzin, Chador Wangdi, Purna Bdr Rai
BACKGROUND: A questionnaire survey was conducted to assess the biosecurity and other practices of backyard poultry holdings and knowledge and practices of poultry keepers following an outbreak of highly pathogenic avian influenza (H5N1) virus in poultry in Thimphu city area, Bhutan. RESULTS: The study identified 62 backyard poultry holdings in 12 settlement areas, and the owners were subsequently interviewed. The birds are kept in a low-input low-output system, fed locally available scavenging feed base, and supplemented with food scraps and some grain...
April 21, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28431421/sevoflurane-posttreatment-attenuates-lung-injury-induced-by-oleic-acid-in-dogs
#20
Guizhi Du, Shurong Wang, Zhuo Li, Jin Liu
BACKGROUND: In animal models, both sevoflurane and propofol protect against acute lung injury (ALI), especially when administered prior to ALI onset. We hypothesized that when compared to propofol, sevoflurane administration after the onset of acute respiratory distress syndrome would mitigate oleic acid (OA)-induced ALI in dogs. METHODS: Dogs were randomly assigned to receive intravenous OA to induce ALI (n = 7 for each OA group) or saline as an OA control (n = 6 for each control)...
May 2017: Anesthesia and Analgesia
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