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https://www.readbyqxmd.com/read/27922210/comparison-between-thoracic-radiographic-findings-and-postmortem-diagnosis-of-thoracic-diseases-in-dyspneic-companion-rats-rattus-norvegicus
#1
Virginie Fouriez-Lablée, Claire Vergneau-Grosset, Philip H Kass, Allison L Zwingenberger
Companion rats are often presented to veterinarians for respiratory difficulties. Dyspnea in rats is most commonly due to infectious pneumonia, and thoracic neoplasia can go undiagnosed ante mortem due to a mistaken interpretation of pneumonia. In domestic carnivores, pulmonary nodular patterns have been shown to correlate with lung neoplastic diseases and infectious diseases. The main objective of this retrospective case series study was to determine whether certain radiographic criteria could be correlated with the presence of thoracic infectious disease and neoplastic disease in companion rats...
December 6, 2016: Veterinary Radiology & Ultrasound
https://www.readbyqxmd.com/read/27921397/nitric-oxide-induced-by-polyamines-involves-antioxidant-systems-against-chilling-stress-in-tomato-lycopersicon-esculentum-mill-seedling
#2
Qian-Nan Diao, Yong-Jun Song, Dong-Mei Shi, Hong-Yan Qi
Polyamines (PAs) and nitric oxide (NO) are vital signals in modulating plant response to abiotic stress. However, to our knowledge, studies on the relationship between NO and PAs in response to cold stress in tomato are limited. Accordingly, in this study, we investigated the effects of putrescine (Put) and spermidine (Spd) on NO generation and the function of Spd-induced NO in the tolerance of tomato seedling under chilling stress. Spd increased NO release via the nitric oxide synthase (NOS)-like and nitrate reductase (NR) enzymatic pathways in the seedlings, whereas Put had no such effect...
2016: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/27921131/multi-biomarker-responses-after-exposure-to-pollution-in-the-mediterranean-mussels-mytilus-galloprovincialis-l-in-the-aegean-coast-of-turkey
#3
Dilara Ozkan, Melih Dagdeviren, Selma Katalay, Adem Guner, N Ülkü Karabay Yavaşoğlu
In this study, sublethal effects on the Mediterranean mussels (Mytilus galloprovincialis L.) collected from the Aegean coast of Turkey were determined. Enzymes such as glutathione-S-transferase (GST), superoxide dismutase (SOD), catalase (CAT), and acetylcholinesterase (AChE), metallothionein (MT) mRNA expressions, thiobarbituric acid reactive substances (TBARS) contents, determination of 14 heavy metals and micronucleus frequency were selected as multibiomarkers. Results show that heavy metals and an increase in the level of MT gene expression have been determined in tissues of mussels collected from all stations...
December 5, 2016: Bulletin of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/27920899/diagnosing-clean-margins-through-raman-spectroscopy-in-human-and-animal-mammary-tumour-surgery-a-short-review
#4
REVIEW
I A Birtoiu, C Rizea, D Togoe, R M Munteanu, C Micsa, M I Rusu, M Tautan, L Braic, L O Scoicaru, A Parau, N D Becherescu-Barbu, M V Udrea, A Tonetto, R Notonier, C E A Grigorescu
Breast cancer frequency in human and other mammal female populations has worryingly increased lately. The acute necessity for taxonomy of the aetiological factors along with seeking for new diagnostic tools and therapy procedures aimed at reducing mortality have yielded in an intense research effort worldwide. Surgery is a regular method to counteract extensive development of breast cancer and prevent metastases provided that negative surgical margins are achieved. This highly technical challenge requires fast, extremely sensitive and selective discrimination between malignant and benign tissues even down to molecular level...
December 6, 2016: Interface Focus
https://www.readbyqxmd.com/read/27920660/neurofibroma-of-the-colon-a-diagnostic-mimicker-of-gastrointestinal-stromal-tumor
#5
Soomin Ahn, Choon Sik Chung, Kyoung-Mee Kim
Gastrointestinal neurofibroma usually develops as diffuse gastrointestinal involvement in neurofibromatosis type 1 patients. Only 4 cases of sporadic colonic neurofibroma in a patient without neurofibromatosis type 1 have been reported in the English literature. A 26-year-old female patient underwent colonoscopy, and a 4-cm-sized polypoid mass was identified in the sigmoid colon. Wedge resection of the mass showed a yellowish, hard submucosal tumor. Microscopically, the tumor was composed of wavy spindle cells, fibroblasts, and strands of collagen; the stroma showed scattered myxoid areas...
September 2016: Case Reports in Gastroenterology
https://www.readbyqxmd.com/read/27920408/asthma-and-other-allergic-diseases-among-saudi-schoolchildren-in-najran-the-need-for-a-comprehensive-intervention-program
#6
Jobran M Alqahtani
BACKGROUND: In the last three decades, an increasing incidence of allergic diseases has been associated with increasing morbidity and mortality in children and young adults. OBJECTIVES: The study aimed to investigate the prevalence and risk factors associated with allergic diseases among Saudi schoolchildren in the southwestern Saudi region of Najran, and to determine the sensitization of patients to a set of allergens. DESIGN: Cross-sectional observational study...
November 2016: Annals of Saudi Medicine
https://www.readbyqxmd.com/read/27919891/structure-activity-relationships-of-a-series-of-echinocandins-and-the-discovery-of-cd101-a-highly-stable-and-soluble-echinocandin-with-distinctive-pharmacokinetic-properties
#7
Kenneth D James, Christopher P Laudeman, Navdeep B Malkar, Radha Krishnan, Karen Polowy
Echinocandins are first-line therapy for candidemia and invasive candidiasis. They are generally safe with few drug interactions, but the stability and pharmacokinetic properties of currently approved echinocandins are such that each was developed for daily intravenous infusion. We sought to discover a novel echinocandin with properties that would enable more flexible dosing regimens, alternate routes of delivery, and expanded utility. Derivatives of known echinocandin scaffolds were generated, and an iterative process of design and screening led to the discovery of CD101, a novel echinocandin that has since demonstrated improved chemical stability and pharmacokinetics...
December 5, 2016: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/27919823/nerve-growth-factor-carbon-nanotube-complex-exerts-prolonged-protective-effects-in-an-in-vitro-model-of-ischemic-stroke
#8
Parichehr Hassanzadeh, Elham Arbabi, Fatemeh Atyabi, Rassoul Dinarvand
AIMS: The therapeutic potential of nerve growth factor (NGF) against the neurological disorders may be negatively affected by its short half-life. Based on the superior properties of carbon nanotubes (CNTs) for controlled drug delivery, we aimed to prepare CNT-NGF complex and evaluate its effect in an in vitro model of ischemic stroke. MATERIALS AND METHODS: Multi-walled CNTs (MWCNTs)-NGF complex was prepared using amino-functionalized COOH-MWCNTs and characterized by Fourier transform infrared spectroscopy and transmission electron microscopy...
December 2, 2016: Life Sciences
https://www.readbyqxmd.com/read/27919804/prevalence-of-giardia-duodenalis-assemblages-and-sub-assemblages-in-symptomatic-patients-from-damascus-city-and-its-suburbs
#9
Dania Skhal, Ghalia Aboualchamat, Ayman Al Mariri, Samar Al Nahhas
Giardia duodenalis is one of the most important human enteric parasites worldwide and is endemic throughout the world with a vast range of mammalian hosts. However, there is limited information on the prevalent genetic variability of G. duodenalis in Syria. This study aimed to evaluate the predominance of G. duodenalis assemblages/sub-assemblages causing humans infection in the city of Damascus and its suburbs. 40 symptomatic giardiasis patients were recruited in this study. Fecal samples were genotyped using PCR/RFLP assay targeting the β-giardin and glutamate dehydrogenase (gdh) genes...
December 2, 2016: Infection, Genetics and Evolution
https://www.readbyqxmd.com/read/27919727/patent-ductus-arteriosus-in-cats-felis-catus-50-cases-2000-2015
#10
A Bascuñán, K M Thieman Mankin, A B Saunders, J M Bright, V Scharf, A Singh, L O'Sullivan, B Brisson, A H Estrada, S P Tou, C Ruoff
OBJECTIVES: To describe signalment, clinical characteristics, diagnostic, treatment, and outcome data in a large case series of cats with patent ductus arteriosus (PDA). ANIMALS: Fifty cats with confirmed PDA. METHODS: Retrospective review of medical records from five referral veterinary hospitals for cats with PDA between 2000 and 2015. Cats were included if a PDA was visualized echocardiographically, during surgery, or on post-mortem examination...
December 2, 2016: Journal of Veterinary Cardiology: the Official Journal of the European Society of Veterinary Cardiology
https://www.readbyqxmd.com/read/27919636/adrenomedullin-and-angiotensin-ii-signaling-pathways-involved-in-the-effects-on-cerebellar-antioxidant-enzymes-activity
#11
Figueira Leticia, Israel Anita
Human adrenomedullin (AM) is a 52-amino acid peptide involved in cardiovascular control. AM has two specific receptors formed by the calcitonin-receptor-like receptor (CRLR) and receptor activity-modifying protein (RAMP) 2 or 3, known as AM1 and AM2 receptors, respectively. In addition, AM has appreciable affinity for the calcitonin gene-1 related peptide receptor (CGRP1), composed of CRLR/RAMP1. In brain, AM and their receptors are expressed in several localized areas, including the cerebellum. AM has been reported as an antioxidant...
December 2, 2016: Brain Research Bulletin
https://www.readbyqxmd.com/read/27919595/the-starting-point-for-bisphosphonate-related-osteonecrosis-of-the-jaw-alveolar-bone-or-oral-mucosa-a-randomized-controlled-experimental-study
#12
Mohammad Zandi, Arash Dehghan, Pejman Janbaz, Hamid Malekzadeh, Payam Amini
OBJECTIVE: Although over a decade has passed since first introduction of BRONJ, the exact pathophysiology of this disease is still unclear. The present experimental study aimed to determine whether the oral mucosa or alveolar bone serves as the starting point for BRONJ development. SUBJECTS AND METHODS: Sixty male Wistar rats were randomly assigned into study and control groups (each, n = 30), and received intraperitoneal injection of 0.06 mg/kg zoledronate and saline, respectively, once a week for 12 weeks...
November 2, 2016: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/27919498/association-between-exposure-to-farm-animals-and-pets-and-risk-of-multiple-sclerosis
#13
Dylan Siejka, Bruce Taylor, Anne-Louise Ponsonby, Terence Dwyer, Ingrid van der Mei
PURPOSE: There exists inconsistent evidence regarding animals including pets as risk factors for the development of Multiple Sclerosis (MS). We investigated the association between farm animals and pets as possible environmental factors in MS development. METHODS: Population based case-control study with 136 clinically definite MS cases and 272 controls randomly chosen from the community matched on sex and age. Data was collected from both questionnaire and a lifetime calendar detailing residence, occupation and pet/animal exposure over the course of participant's lives...
November 2016: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/27919269/comparison-of-voluntary-food-intake-and-palatability-of-commercial-weight-loss-diets-in-healthy-dogs-and-cats
#14
Marie Anne Hours, Emmanuelle Sagols, Ariane Junien-Castagna, Alexandre Feugier, Delphine Moniot, Ingrid Daniel, Vincent Biourge, Serisier Samuel, Yann Queau, Alexander J German
BACKGROUND: Obesity in dogs and cats is usually managed by dietary energy restriction using a purpose-formulated weight loss diet, but signs of hunger and begging commonly occur causing poor owner compliance. Altering diet characteristics so as to reduce voluntary food intake (VFI) can improve the likelihood of success, although this should not be at the expense of palatability. The aim of the current study was to compare the VFI and palatibility of novel commercially available canine and feline weight loss diets...
December 5, 2016: BMC Veterinary Research
https://www.readbyqxmd.com/read/27919262/erratum-to-clinical-evaluation-of-a-nutraceutical-diet-as-an-adjuvant-to-pharmacological-treatment-in-dogs-affected-by-keratoconjunctivitis-sicca
#15
Simona Destefanis, Daniela Giretto, Maria Cristina Muscolo, Alessandro Di Cerbo, Gianandrea Guidetti, Sergio Canello, Angela Giovazzino, Sara Centenaro, Giuseppe Terrazzano
No abstract text is available yet for this article.
December 5, 2016: BMC Veterinary Research
https://www.readbyqxmd.com/read/27919005/tracking-listeria-monocytogenes-contamination-and-virulence-associated-characteristics-in-the-ready-to-eat-meat-based-food-products-industry-according-to-the-hygiene-level
#16
A R Henriques, L T Gama, M J Fraqueza
Listeria monocytogenes isolates collected from final products and food contact surfaces of 10 ready-to-eat meat-based food products (RTEMP) producing industries were analyzed to relate their virulence-associated characteristics and genetic profiles with the hygiene assessment of those industries. Together with sample collection, an audit was performed to evaluate the implemented food safety management system and to investigate the specific audit requisites more associated to the occurrence of those L. monocytogenes serogroups frequently related with human disease...
November 21, 2016: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/27918999/effect-of-silver-nanoparticles-on-the-metabolic-rate-hematological-response-and-survival-of-juvenile-white-shrimp-litopenaeus-vannamei
#17
Karla Juarez-Moreno, Claudio Humberto Mejía-Ruiz, Fernando Díaz, Horacio Reyna-Verdugo, Ana Denisse Re, Edgar F Vazquez-Felix, Edna Sánchez-Castrejón, Josué D Mota-Morales, Alexey Pestryakov, Nina Bogdanchikova
White spot syndrome virus (WSSV) is highly lethal and contagious in shrimps; its outbreaks causes an economic crisis for aquaculture. Several attempts have been made to treat this disease; however, to date, there is no effective cure. Because of their antimicrobial activities, silver nanoparticles (AgNPs) are the most studied nanomaterial. Although the antiviral properties of AgNPs have been studied, their antiviral effect against viral infection in aquaculture has not been reported. The AgNPs tested herein are coated with polyvinylpyrrolidone (PVP) and possess multiple international certifications for their use in veterinary and human applications...
December 2, 2016: Chemosphere
https://www.readbyqxmd.com/read/27918945/constructed-wetlands-for-the-removal-of-metals-from-livestock-wastewater-can-the-presence-of-veterinary-antibiotics-affect-removals
#18
C Marisa R Almeida, Filipa Santos, A Catarina F Ferreira, Carlos Rocha Gomes, M Clara P Basto, Ana P Mucha
The presence of emergent antibiotics, in livestock wastewater may affect constructed wetlands (CWs) performance in the removal of other pollutants. The main objective of this study was to evaluate the influence of two antibiotics commonly used in livestock industry, enrofloxacin and ceftiofur, on metal removal by CWs. Microcosms (0.4m×0.3m×0.3m), simulating CWs, were constructed with Phragmites australis to treat livestock wastewater spiked or not with 100µg/L of enrofloxacin or ceftiofur (individually or in mixture)...
December 2, 2016: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/27918918/esr-dating-of-smilodon-populator-from-toca-de-cima-dos-pil%C3%A3-o-piau%C3%A3-brazil
#19
Angela Kinoshita, Michelle Mollemberg, William Santana, Ana Maria G Figueiredo, Niede Guidon, Maria de Fátima da Luz, Claude Guérin, Oswaldo Baffa
Smilodon is a genus of big cats that lived from the early to the late Pleistocene in regions extending from North to South America. The fossil records of the "saber-toothed cats" are uneven, with some taxa being quite abundant in certain regions. In Brazil, Smilodon populator is a well-known species whose remains, although scarce in comparison to other large mammals, are found all across the country. In particular, there are multiple records of this species in the region of the Serra da Capivara National Park...
November 22, 2016: Applied Radiation and Isotopes
https://www.readbyqxmd.com/read/27918890/differential-expression-on-mitochondrial-tryparedoxin-peroxidase-mtctxnpx-in-trypanosoma-cruzi-after-ferrocenyl-diamine-hydrochlorides-treatments
#20
Andréa A N Kohatsu, Flávia A J Silva, Acácio I Francisco, Aline Rimoldi, Marco T A Silva, Maria D Vargas, João A da Rosa, Regina M B Cicarelli
Resistance to benznidazole in certain strains of Trypanosoma cruzi may be caused by the increased production of enzymes that act on the oxidative metabolism, such as mitochondrial tryparedoxin peroxidase (mTcTXNPx) which catalyses the reduction of peroxides. This work presents cytotoxicity assays performed with ferrocenyl diamine hydrochlorides in six different strains of T. cruzi epimastigote forms (Y, Bolivia, SI1, SI8, QMII, and SIGR3). The last four strains have been recently isolated from triatominae and mammalian host (domestic cat)...
December 2, 2016: Brazilian Journal of Infectious Diseases
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