keyword
https://read.qxmd.com/read/38547236/volumetric-quantification-identifies-some-left-atrial-dilations-undetected-by-left-atrium-aorta-ratio-measurements-a-prospective-echocardiographic-study-in-155-cavalier-king-charles-spaniels-with-and-without-degenerative-mitral-valve-disease
#1
JOURNAL ARTICLE
Valérie Chetboul, Camille Poissonnier, Pierre Foulex, Maria Paz Alvarado, Émilie Trehiou-Sechi, Vittorio Saponaro, Peggy Passavin, Loïc Desquilbet
INTRODUCTION: Degenerative mitral valve disease (DMVD) is the most common canine heart disease with a high predisposition in Cavalier King Charles Spaniels (CKCSs). Mitral regurgitation related to DMVD can lead to left atrial (LA) dilation, which is associated with survival time. Left-atrial-to-aortic (LA:Ao) ratio assessed by two-dimensional echocardiography is commonly used to evaluate LA size. The objectives of this prospective observational study were therefore 1) to compare different echocardiographic methods (i...
2024: PloS One
https://read.qxmd.com/read/38547160/in-vitro-activity-of-selected-antimicrobials-against-methicillin-resistant-staphylococcus-pseudintermedius-of-canine-origin-in-poland
#2
JOURNAL ARTICLE
Magdalena Kizerwetter-Świda, Dorota Chrobak-Chmiel, Ilona Stefańska, Ewelina Kwiecień, Magdalena Rzewuska
BACKGROUND: Methicillin-resistant Staphylococcus pseudintermedius (MRSP) is an important veterinary pathogen. In general, only a few antimicrobials show in vitro activity against MRSP isolates. OBJECTIVES: The objective of this study was to determine the in vitro activity of selected antimicrobials, including last-choice drugs, against clinical MRSP isolates of canine origin. The activity of 10 selected agents was evaluated against 41 clinical MRSP isolates. METHODS: The disk diffusion method and minimal inhibitory concentration values were used for antimicrobial susceptibility testing (AST)...
May 2024: Veterinary Medicine and Science
https://read.qxmd.com/read/38546870/comparative-mri-analysis-of-the-forebrain-of-three-sauropsida-models
#3
JOURNAL ARTICLE
S Jiménez, I Santos-Álvarez, E Fernández-Valle, D Castejón, P Villa-Valverde, C Rojo-Salvador, P Pérez-Llorens, M J Ruiz-Fernández, S Ariza-Pastrana, R Martín-Orti, Juncal González-Soriano, Nerea Moreno
The study of the brain by magnetic resonance imaging (MRI) allows to obtain detailed anatomical images, useful to describe specific encephalic structures and to analyze possible variabilities. It is widely used in clinical practice and is becoming increasingly used in veterinary medicine, even in exotic animals; however, despite its potential, its use in comparative neuroanatomy studies is still incipient. It is a technology that in recent years has significantly improved anatomical resolution, together with the fact that it is non-invasive and allows for systematic comparative analysis...
March 28, 2024: Brain Structure & Function
https://read.qxmd.com/read/38546809/comparative-genetic-and-pathogenic-approaches-of-escherichia-coli-isolated-simultaneously-from-pyometra-and-urine-of-bitches
#4
JOURNAL ARTICLE
Cassiane Elisabete Lopes, Tainara Soares Weyh, Camila Azevedo Moni, Maria Eduarda Dias, Tania Aparecida Tardelli Gomes, Mateus Matiuzzi da Costa, Rommel Thiago Jucá Ramos, Aristóteles Góes-Neto, Vasco Ariston de Carvalho Azevedo, Bertram Brenig, Franciele Maboni Siqueira
Escherichia coli (E. coli) are widely related to pyometra and cystitis in dogs, and these infections can occur simultaneously. The goal of this study was to determine genetic and pathogenic insights of 14 E. coli isolated simultaneously from pyometra content and bladder urine of seven bitches. To achieve this, in silico and in vitro comparative analyses were conducted. Whole-genome comparisons demonstrated that E. coli isolated from pyometra and urine of the same animal were predominantly genetic extraintestinal E...
March 28, 2024: Veterinary Research Communications
https://read.qxmd.com/read/38546392/complete-in-vitro-reconstitution-of-the-apramycin-biosynthetic-pathway-demonstrates-the-unusual-incorporation-of-a-%C3%AE-d-sugar-nucleotide-in-the-final-glycosylation-step
#5
JOURNAL ARTICLE
Shusuke Sato, Po-Hsun Fan, Yu-Cheng Yeh, Hung-Wen Liu
Apramycin is a widely used aminoglycoside antibiotic with applications in veterinary medicine. It is composed of a 4-amino-4-deoxy-d-glucose moiety and the pseudodisaccharide aprosamine, which is an adduct of 2-deoxystreptamine and an unusual eight-carbon bicyclic dialdose. Despite its extensive study and relevance to medical practice, the biosynthetic pathway of this complex aminoglycoside nevertheless remains incomplete. Herein, the remaining unknown steps of apramycin biosynthesis are reconstituted in vitro , thereby leading to a comprehensive picture of its biological assembly...
March 28, 2024: Journal of the American Chemical Society
https://read.qxmd.com/read/38546192/comparison-of-doppler-ultrasonic-sphygmomanometry-oscillometry-and-high-definition-oscillometry-for-non-invasive-blood-pressure-measurement-in-conscious-cats
#6
JOURNAL ARTICLE
Marieke Knies, Erik Teske, Hans Kooistra
OBJECTIVES: Systemic arterial hypertension is a common occurrence and can have serious adverse consequences in cats. Therefore, measuring blood pressure is very important. There are many indirect blood pressure measurement devices available. This study compared Doppler, oscillometric (petMAP Graphic II, SunTech Vet20, the Cardell Insight-X0000) and high-definition oscillometry devices for the non-invasive measurement of blood pressure in conscious cats. METHODS: In this prospective study, blood pressure was measured in 32 cats using the different devices according to the recommendations of the American College of Veterinary Internal Medicine Consensus Statement...
March 2024: Journal of Feline Medicine and Surgery
https://read.qxmd.com/read/38546115/management-of-canine-wounds-using-platelet-rich-fibrin-prf-biomaterial-a-case-series-report
#7
JOURNAL ARTICLE
Carla S Soares, Isabel R Dias, Luís C Barros, Maria Dos Anjos Pires, Pedro P Carvalho
BACKGROUND: The increasing interest in platelet-based therapies has underwritten the development of novel veterinary regenerative treatments. The haemoderivative platelet-rich fibrin (PRF) comprises abundant concentrations of platelets and leucocytes, above the physiologic baseline, which are considered essential elements for wound regeneration, stimulating local angiogenesis, cellular migration, proliferation and differentiation, considered essential for skin repair. OBJECTIVES: This study aimed to describe the treatment of eight dogs with naturally occurring cutaneous wounds, where autologous PRF therapy was applied, using a protocol developed by our group...
May 2024: Veterinary Medicine and Science
https://read.qxmd.com/read/38546016/prevalence-and-antimicrobial-resistance-profiles-of-mastitis-causing-bacteria-isolated-from-dairy-goats-in-mukurweini-sub-county-nyeri-county-kenya
#8
JOURNAL ARTICLE
Sarah Kabui, Josephine Kimani, Caroline Ngugi, John Kagira
BACKGROUND: Ruminant mastitis continues to be a cause of economic losses in the dairy industry and remains a major public health hazard globally. OBJECTIVES: This cross-sectional study was carried out in Mukurweini Sub-County of Nyeri County, Kenya, to investigate the prevalence of bacteria causing mastitis, risk factors associated with goat mastitis and the antibiotic resistance profiles of bacteria isolated from the goat milk. METHODS: Farm level data on risk factors for mastitis was obtained from 56 farmers using a semi structured questionnaire...
May 2024: Veterinary Medicine and Science
https://read.qxmd.com/read/38545908/spread-and-persistence-of-antimicrobial-resistance-genes-in-wastewater-from-human-and-animal-sources-in-s%C3%A3-o-paulo-brazil
#9
JOURNAL ARTICLE
Milena Dropa, Jéssica Santiago Bispo da Silva, André Furugen César Andrade, Denis Hideki Nakasone, Marcos Paulo Vieira Cunha, Gesiane Ribeiro, Ronalda Silva de Araújo, Carlos Jesus Brandão, Barbara Ghiglione, Nilton Lincopan, Maria Inês Zanoli Sato, Terezinha Knöbl
The spread of antimicrobial resistance (AMR) through multiple reservoirs is a global concern. Wastewater is a critical AMR dissemination source, so this study aimed to assess the persistence of resistance genetic markers in wastewater using a culture-independent approach. Raw and treated wastewater samples (n = 121) from a wastewater treatment plant (WWTP), a human hospital, a veterinary hospital, and a pig farm were monthly collected and concentrated by filtration. DNA was extracted directly from filter membranes, and PCR was used in the qualitative search of 32 antimicrobial resistance genes (ARGs)...
March 28, 2024: Tropical Medicine & International Health
https://read.qxmd.com/read/38545844/genomic-regions-and-biological-pathways-associated-with-sex-limited-reproductive-traits-in-bovine-species
#10
JOURNAL ARTICLE
Babatunde S Olasege, Zhen Yin Oh, Muhammad S Tahir, Laercio R Porto-Neto, Ben J Hayes, Marina R S Fortes
Many animal species exhibit sex-limited traits, where certain phenotypes are exclusively expressed in one sex. Yet, the genomic regions that contribute to these sex-limited traits in males and females remain a subject of debate. Reproductive traits are ideal phenotypes to study sexual differences since they are mostly expressed in a sex-limited way. Therefore, this study aims to use local correlation analyses to identify genomic regions and biological pathways significantly associated with male and female sex-limited traits in two distinct cattle breeds (Brahman (BB) and Tropical Composite (TC))...
March 28, 2024: Journal of Animal Science
https://read.qxmd.com/read/38545834/comparative-disposition-kinetics-of-oral-deracoxib-in-sheep-and-goats
#11
JOURNAL ARTICLE
Charbel Fadel, Beata Łebkowska-Wieruszewska, Andrzej Lisowski, Firas Serih, Amnart Poapolathep, Mario Giorgi
This study investigates the pharmacokinetics (PK) of deracoxib (DX), a selective COX-2 inhibitor, in sheep and goats following a single oral dose. DX, approved for dogs, holds potential as an alternative NSAID in small ruminants, particularly in light of heightened concern regarding abomasal ulceration. The study employed an oral administration of DX at a dose of 150 mg/head (sheep and goats), and plasma concentrations were determined after validating a high-performance liquid chromatography method, coupled to a UV detector...
March 28, 2024: Journal of Veterinary Pharmacology and Therapeutics
https://read.qxmd.com/read/38545561/electrical-impedance-tomography-in-anaesthetised-chickens-gallus-domesticus
#12
JOURNAL ARTICLE
Adrian M Wong, Hei Y Lum, Gabrielle C Musk, Timothy H Hyndman, Andreas D Waldmann, Deborah J Monks, Ross S Bowden, Martina Mosing
The applicability of electrical impedance tomography (EIT) in birds is unknown. This study aimed to evaluate the use of EIT in anaesthetised chickens in four recumbency positions. Four adult Hyline chickens were anaesthetised with isoflurane in oxygen, and intubated endotracheally for computed tomography (CT). A rubber belt was placed around the coelom caudal to the shoulder joint. A chicken-specific finite element (FE) model, which is essential to generate anatomically accurate functional EIT images for analysis, was constructed based on the CT images obtained at the belt level...
2024: Frontiers in Veterinary Science
https://read.qxmd.com/read/38545560/case-report-necrotizing-leukomyelitis-and-meningitis-in-a-pomeranian
#13
Koen M Santifort, Laurent Garosi, Erik A W S Weerts
A 2.5-year-old female entire Pomeranian dog was presented for acute paraparesis progressing within 2 days to paraplegia. General physical examination was unremarkable. Neurological examination showed paraplegia without nociception, a mass reflex upon testing perineal reflexes and withdrawal reflexes in the pelvic limbs and patellar hyperreflexia. Cutaneous trunci reflexes were absent caudal to the level of the 6th thoracic vertebra. Spinal hyperesthesia was present. Neuroanatomical localization was consistent with a T3-L3 myelopathy...
2024: Frontiers in Veterinary Science
https://read.qxmd.com/read/38545559/construction-and-characterization-of-a-reverse-genetics-system-of-bovine-parainfluenza-virus-type-3c-as-a-tool-for-rapid-screening-of-antivirals-in-vitro
#14
JOURNAL ARTICLE
Yu Han, Kejia Lu, Riteng Zhang, Xi Wei, Hanwei Guo, Lina Tong, Xinglong Wang, Sa Xiao, Haijin Liu, Zengqi Yang
Bovine parainfluenza virus type 3 (BPIV3) is a key pathogen associated with bovine respiratory disease complex (BRDC). However, its specific pathogenesis mechanisms have not been fully elucidated. Reverse genetics provides a useful method for understanding the pathogenic mechanism of BPIV3. To ensure the functionality of the rescue platforms, we first constructed a minigenome (MG) system of BPIV3 utilizing a 5-plasmid system in this investigation. Then, a full-length infection clone of BPIV3 was obtained from the SX-2021 strain, and different methods were employed to identify the rescued virus...
2024: Frontiers in Veterinary Science
https://read.qxmd.com/read/38545558/wild-boar-sus-scrofa-carcasses-as-an-attraction-for-scavengers-and-a-potential-source-for-soil-contamination-with-the-african-swine-fever-virus
#15
JOURNAL ARTICLE
Lea Tummeleht, Susanna Suvi Siviä Häkkä, Margret Jürison, Annika Vilem, Imbi Nurmoja, Arvo Viltrop
The wild boar ( Sus scrofa ) is a social animal species native to Eurasia. During the last decade, the wild boar population in Estonia has been severely affected by the African swine fever virus (ASFV), which has also affected domestic pig farming. The potential transmission routes of ASFV remain unclear and are currently under intensive investigation. This pilot study aimed to clarify the frequency and characteristics of contacts between living wild boars and the carcasses of their conspecifics, which could play a role in the transmission of ASFV...
2024: Frontiers in Veterinary Science
https://read.qxmd.com/read/38545440/next-generation-sequencing-metabarcoding-assays-reveal-diverse-bacterial-vector-borne-pathogens-of-mongolian-dogs
#16
JOURNAL ARTICLE
Cassandra Davitt, Lucas G Huggins, Martin Pfeffer, Lkhagvasuren Batchimeg, Malcolm Jones, Banzragch Battur, Anke K Wiethoelter, Rebecca Traub
Bacterial vector-borne pathogens (BVBPs) negatively impact canine health worldwide, with several also being zoonotic, posing an additional disease risk to humans. To date, BVBPs have been reported in humans and various sylvatic and domestic animal hosts across multiple Mongolian aimags (provinces); however, there has been no published data on these pathogens within Mongolia's canine populations. Collection of such data is important given Mongolia's size, diverse number of climatic regions, and large population of dogs, most of which closely share their environment with humans and livestock...
2024: Curr Res Parasitol Vector Borne Dis
https://read.qxmd.com/read/38545179/fungal-metabolite-6-pentyl-%C3%AE-pyrone-reduces-canine-coronavirus-infection
#17
JOURNAL ARTICLE
Claudia Cerracchio, Luca Del Sorbo, Francesco Serra, Alessia Staropoli, Maria Grazia Amoroso, Francesco Vinale, Filomena Fiorito
Canine coronavirus (CCoV) can produce a self-limited enteric disease in dogs but, because of notable biological plasticity of coronaviruses (CoVs), numerous mutations as well as recombination events happen leading to the emergence of variants often more dangerous for both animals and humans. Indeed, the emergence of new canine-feline recombinant alphacoronaviruses, recently isolated from humans, highlight the cross-species transmission potential of CoVs. Consequently, new effective antiviral agents are required to treat CoV infections...
March 30, 2024: Heliyon
https://read.qxmd.com/read/38545134/comparison-between-basal-arch-width-in-normal-occlusions-and-class-%C3%A2-malocclusions-by-using-cone-beam-computed-tomography
#18
JOURNAL ARTICLE
Haolin Zhang, Donghui Guo, Yanning Ma, Yuerong Xu, Zuolin Jin, Hao Zhang, Jie Gao
OBJECTIVE: The purpose of this research was to investigate the measurements of maxillary and mandibular basal arch width in male and female with normal occlusion, and to compare dental arch width difference between normal occlusion and ClassⅡ malocclusion groups could be helpful in orthodontic diagnosis and treatment planning. METHODS: Cone-beam computed tomography (CBCT) images from 133 individuals (76 males and 57 females) with normal occlusion and 64 (25 males and 39 females) with skeletal Class II malocclusions were evaluated...
March 30, 2024: Heliyon
https://read.qxmd.com/read/38544871/effects-of-restraint-stress-and-surface-treatments-on-the-stability-of-titanium-dental-implant-osseointegration-in-dogs-an-in%C3%A2-vivo-comparative-study
#19
JOURNAL ARTICLE
Mohammed A Abdulla, Radhwan H Hasan, Osama H Al-Hyani
OBJECTIVES: This study was aimed at assessing the effects of restraint stress and sandblasting; sandblasting with acid etching; Er-Cr: YSGG laser treatment; and propolis coating of implant surfaces on the implant stability quotient (ISQ) of grade 4 titanium dental implant osseointegration in model dogs. METHODS: A total of forty-eight CPTi dental implants were divided into four groups according to surface treatment: group A: sandblasting with acid etching; group B: sandblasting with Al2 O3 ; group C: Er-Cr: YSGG laser; and group D: propolis coating...
June 2024: Journal of Taibah University Medical Sciences
https://read.qxmd.com/read/38544558/ionizing-radiation%C3%A2-induced-modification-of-nialamide-as-an-anti%C3%A2-inflammatory-agent-against-lipopolysaccharide%C3%A2-induced-raw-264-7-and-dh82-cells
#20
JOURNAL ARTICLE
Hanui Lee, Gyeong Han Jeong, So-Yeun Woo, Hyo Jin Choi, Byung Yeoup Chung, Kyung-Bon Lee, Hyoung-Woo Bai
Nialamide is a non-selective monoamine oxidase inhibitor that was widely used as an antidepressant. However, it has been prohibited for decades in the depressive medicine market due to the adverse hepatotoxic side effects. The re-use of drugs that have been withdrawn from the market represents a promising approach for the development of novel incrementally modified drugs and, in this context, ionizing radiation can serve as a powerful tool for producing new drug candidates. The present study exposed nialamide to γ radiation at 50 kGy to obtain the novel cyclized benzylamide, nialaminosin (compound 2), along with five known compounds, 3-amino- N -benzylpropanamide (compound 3), 3-methoxy- N -benzylpropanamide (compound 4), 3-hydroxy- N -benzylpropanamide (HBPA; compound 5), N -benzylpropanamide (compound 6) and isonicotinamide (compound 7)...
May 2024: Experimental and Therapeutic Medicine
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