Read by QxMD icon Read


Caren E Smith, Jack L Follis, Jennifer A Nettleton, Millennia Foy, Jason H Y Wu, Yiyi Ma, Toshiko Tanaka, Ani W Manichakul, Hongyu Wu, Audrey Y Chu, Lyn M Steffen, Myriam Fornage, Dariush Mozaffarian, Edmond K Kabagambe, Luigi Ferruci, Yii-Der Ida Chen, Stephen S Rich, Luc Djoussé, Paul M Ridker, Weihong Tang, Barbara McKnight, Michael Y Tsai, Stefania Bandinelli, Jerome I Rotter, Frank B Hu, Daniel I Chasman, Bruce M Psaty, Donna K Arnett, Irena B King, Qi Sun, Lu Wang, Thomas Lumley, Stephanie E Chiuve, David S Siscovick, José M Ordovás, Rozenn N Lemaitre
SCOPE: Tissue concentrations of omega-3 fatty acids may reduce cardiovascular disease risk, and genetic variants are associated with circulating fatty acids concentrations. Whether dietary fatty acids interact with genetic variants to modify circulating omega-3 fatty acids is unclear. We evaluated interactions between genetic variants and fatty acid intakes for circulating alpha-linoleic acid, eicosapentaenoic acid, docosahexaenoic acid, and docosapentaenoic acid. METHODS AND RESULTS: We conducted meta-analyses (N = 11 668) evaluating interactions between dietary fatty acids and genetic variants (rs174538 and rs174548 in FADS1 (fatty acid desaturase 1), rs7435 in AGPAT3 (1-acyl-sn-glycerol-3-phosphate), rs4985167 in PDXDC1 (pyridoxal-dependent decarboxylase domain-containing 1), rs780094 in GCKR (glucokinase regulatory protein), and rs3734398 in ELOVL2 (fatty acid elongase 2))...
July 2015: Molecular Nutrition & Food Research
Oscar Pineda-Catalan, Susan L Perkins, Michael A Peirce, Rachel Engstrand, Carmen Garcia-Davila, Miguel Pinedo-Vasquez, A Alonso Aguirre
Pigmented hemosporidian parasites that do not exhibit erthyrocytic schizogony, and infect birds, chelonians, and squamates, have been classified in various genera over time. These classifications have reflected vertebrate hosts, insect vectors, and variations in morphology and life history observed in representative species. Side-necked turtles ( Podocnemis spp.) from the Peruvian Amazon were screened for hemoparasites and 2 species of hemosporid parasites infecting these hosts were observed. Molecular phylogenetic analysis of these new isolates, along with parasites from lizards, a snake, and a variety of Haemoproteus species from birds from both the Haemoproteus and Parahaemoproteus subgenera, strongly support the separation of the non-avian parasites into a separate genus...
December 2013: Journal of Parasitology
Veron Ramsuran, Hemant Kulkarni, Weijing He, Koleka Mlisana, Edwina J Wright, Lise Werner, John Castiblanco, Rahul Dhanda, Tuan Le, Matthew J Dolan, Weihua Guan, Robin A Weiss, Robert A Clark, Salim S Abdool Karim, Sunil K Ahuja, Thumbi Ndung'u
BACKGROUND: The Duffy-null trait and ethnic netropenia are both highly prevalent in Africa. The influence of pre-seroconversion levels of peripheral blood cell counts (PBCs) on the risk of acquiring human immunodeficiency virus (HIV)-1 infection among Africans is unknown. METHODS: The triangular relationship among pre-seroconversion PBC counts, host genotypes, and risk of HIV acquisition was determined in a prospective cohort of black South African high-risk female sex workers...
May 2011: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
No abstract text is available yet for this article.
November 1954: Il Sangue
A L Buchwald, M Müller
Methyl bromide poisoning is difficult to confirm because routine laboratory testing has not been reliable. Measurable levels of the parent agent are rapidly reduced, probably as a result of direct tissue chemical reaction. Serum bromide levels have been used as an indirect measure of exposure and/or toxicity but are inconsistent. Recently special testing has shown that protein adducts formed after exposure to methyl bromide may be a better measure of significant exposure. The S-methylcysteine adduct was used to confirm acute methyl bromide toxicity 10 weeks after an exposure...
August 2001: Veterinary and Human Toxicology
A So, A M Chamot, V Péclat, J C Gerster
OBJECTIVE: Metalloproteinases (MMP) play an important role in the remodelling of the extracellular matrix. However, evidence that they are responsible for tissue damage in pathological situations remains circumstantial. Stromelysin (MMP-3) production is increased in rheumatoid arthritis (RA), and has been proposed as a marker of joint damage. The relevance of serum levels of MMP-3 to erosions in RA was studied. METHODS: Fifty-three patients with active RA of > 5 yr duration and with available X-rays were stratified according to disease duration...
May 1999: Rheumatology
R Dahm, C Gribbon, R A Quinlan, A R Prescott
Nuclear elimination accompanies differentiation in such specialized cell types such as erthyrocytes and lens fibre cells. It also accompanies apoptosis which has suggested that similar processes could operate in both. Denucleation occurs in the lens in order to reduce light scatter and this process is often disrupted in cataract. Using the adult bovine lens as a model system, nuclear changes accompanying denucleation are described with particular emphasis on the lamina, nucleolar and coiled body compartments in lens nuclei...
March 1998: European Journal of Cell Biology
L S Marton, B K Weir, H Zhang
Endothelial cells are affected in the cerebral vasospasm that occurs at the time of erthyrocyte lysis in a subarachnoid clot. A red blood cell lysate was added to bovine pulmonary artery endothelial cells in vitro to determine whether hemolysate can trigger tyrosine kinase mediated cell signalling and if so, whether this signal is independent of the elevation of intracellular free calcium levels, [Ca2+]i induced by hemolysate. Hemolysate was found by Western blotting to induce a dose dependent increase in the level of tyrosine phosphorylation of two proteins, approximately 60 and 110 kD, that was maximal between 1 and 2 min...
August 1996: Neurological Research
G Lönnerholm
Rat liver and rabbit skeletal muscle were studied by Hansson's method for histochemical demonstration of carbonic anhydrase activity. In histochemical model experiments purified male rat liver carbonic anhydrase was much more resistant to acetazolamide than rat erythrocyte carbonic anhydrase. Male rat liver slices showed cytoplasmic staining, which was about 1000 times more resistant to acetazolamide and ethoxzolamide than that of female rat liver or erthyrocytes of either sex. Rabbit skeletal muscle slices showed staining at the sarcolemma of all fibers, whereas the staining of the sarcoplasm varied...
May 1980: Journal of Histochemistry and Cytochemistry: Official Journal of the Histochemistry Society
D A Bemis, B J Plotkin
A total of 53 isolates of Bordetella bronchiseptica from dogs and pigs were tested for their ability to agglutinate chicken, horse, sheep, dog, pig, and guinea pig erythrocytes. No differences in hemagglutinating activity were attributed to the animal origin of the bordetella isolates. Horse and dog erythrocytes consistently resulted in the strongest hemagglutination reactions, whereas only 4% of the B. bronchiseptica isolates produced weak agglutination of chicken erythrocytes. A total of 85% of the isolates agglutinated horse, sheep, dog, pig, and guinea pig erythrocytes...
June 1982: Journal of Clinical Microbiology
M Champagne, A Mazen
No abstract text is available yet for this article.
December 18, 1967: Comptes Rendus Hebdomadaires des Séances de L'Académie des Sciences. Série D: Sciences Naturelles
J E Szilagyi, J B Senturia
No abstract text is available yet for this article.
October 1974: Cryobiology
M Grieger, I Günther, G Jacobasch, D Buss, C Gerth
No abstract text is available yet for this article.
1972: Haematologia
L D Krymdkiĭ, G V Nestaĭko, A G Rybalov, S A Shanoian
Erthyrocytes can form cytoplasmatic bridged connecting with each other individual cells or a great number of cells into a conglomerate. The cytoplasmatic bridges--is a peculiar form of existance of erythrocytes which differ from the forms described earlier: thorm-like (spheroechinocytes) and myelino-like forms having nothing in common with the mechanism of agglutination. The cytoplasmatic bridges of erythrocytes were found in man, dogs and guinea-pigs irrespective of a disease or conditions of an experiment, i...
1975: Arkhiv Patologii
J B Stamatoff, S Krimm, N R Harvie
Small angle x-ray diffraction patterns have been obtained from ordered arrays of hemoglobin-free human erthyrocyte membranes by use of improved techniques. Diffraction data have been recorded to 9 A resolution on samples whose lattice periodicity was varied (by changing humidity) from 55.5 A to 69.6 A. The observed reflections permitted tracing the intensity transform of the membranes. Phases for the reflections were assigned by the minimum wavelength principle. An electron density profile was then obtained by Fourier inversion, and yielded a symmetric membrane about 55 A in width...
February 1975: Proceedings of the National Academy of Sciences of the United States of America
J C Ridway, G M Taylor, C B Freeman, R Harris
Immunoglobulin (Fc) receptors were detected on leucocytes from patients with acute myeloid leukaemia (AML) by rosette formation with human cDE/cDE erthyrocytes (HE) sensitized with Rhesus (Rh) antisera (HEA). Of 7 Rh antisera tested, erythrocytes sensitized with anti-d (Gm10) detected the highest numbers of rosette-forming cells (HEA-RFC) in normal and AML leucocyte preparations. Using this assay, HEA-RFC was studied in 22 untreated AML patients and ce assay detected 11-6% lymphocyte and 2-1% granulocyte HEA-RFC in normal peripheral blood...
October 1976: British Journal of Cancer
C A Facer, R S Bray, J Brown
Gambian children with past or present Plasmodium falciparum malaria were investigated for the incidence of Coombs positivity using monospecific antisera. Approximately 50% were positive and the most frequent form of erythrocyte sensitization was with C3d. Other specificities, EIgG, EIgGC3d and EIgGC4bC3d were less common. Erthyrocytes were never found sensitized with IgA or IgM. There was no correlation between a positive test and age, tribal status or level of parasitaemia at presentation, although a positive test was often found in association with anaemia...
January 1979: Clinical and Experimental Immunology
G Vidali, L C Boffa, E M Bradbury, V G Allfrey
Exposure of HeLa cells to Na butyrate leads to an accumulation of multiacetylated forms of histones H3 and H4. Our studies of histone acetylation in HeLa S-3 cells show that 7 mM butyrate suppresses the deacetylation of histones without influencing the rate of radioactive acetate incorporation. An alteration in nucleosome structure in highly acetylated chromatin is indicated by an increased rate of DNA degradation by DNase I. A close association of acetylated histones with the DNase I-sensitive sequences is confirmed by the finding that histones remaining after limited DNase I digestion are depleted in the multiacetylated forms of histones H3 and H4...
May 1978: Proceedings of the National Academy of Sciences of the United States of America
M D Foadi, A M Slater, G D Pegrum
Phagocytosis of erthyrocytes and platelets by bone marrow blast cells has been noted in 4 patients in the late relapse of acute lymphoblastic leukaemia (ALL). The underlying mechanism is unclear but prolonged course of the disease seems to be a major factor in the emergence of cells with phagocytic properties.
January 1978: Scandinavian Journal of Haematology
N Minamoto, K Kurata, I Kaizuka, H Sazawa
Chicken embryo cells infected with the HEP Flury strain of rabies virus adapted to tissue culture produced a hemadsorption (HAD) phenomenon by using goose erthyrocytes. The optimal conditions for HAD included the incubation of cell cultures at 37C for 3 days after virus inoculation, the use of a 0.4% suspension of goose erythrocytes in phosphate buffer adjusted at pH 6.2, and adsorption of erythrocytes at 4C. This phenomenon was inhibited with anti-rabies serum. Virus titer obtained with the HAD technique was almost the same as with the fluorescent antibody technique or the intracerebral inoculation of suckling mice...
May 1976: Infection and Immunity
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"