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https://www.readbyqxmd.com/read/28550796/a-novel-tertiary-prep-hplc-method-for-the-isolation-of-single-amino-acids-for-ams-radiocarbon-measurement
#1
Ricardo Fernandes, Tomas Koudelka, Andreas Tholey, Alexander Dreves
AMS-radiocarbon measurements of amino acids can potentially provide more reliable radiocarbon dates than bulk collagen analysis. Nonetheless, the applicability of such an approach is often limited by the low-throughput of existing isolation methods and difficulties in determining the contamination introduced during the separation process. A novel tertiary prep-HPLC amino acid isolation method was developed that relies on the combustion of eluted material without requiring any additional chemical steps. Amino acid separation was carried out using a gradient mix of pure water and phosphoric acid with an acetonitrile step in-between runs to remove hydrophobic molecules from the separation column...
May 15, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/28550667/-clinical-features-and-risk-factors-for-recurrence-in-mucinous-breast-cancer
#2
L Lei, Z Z Chen, Y B Zheng, B Chen, X Wang, X J Wang
Objective: To investigate the clinicopathological characteristic and risk factors for recurrence in different subtypes of mucinous breast cancer(MBC). Methods: Clinical data of 97 MBC patients at Zhejiang Cancer Hospital from August 2005 to November 2012 were retrospectively analyzed. All of patients were divided into 3 subtypes according to the mucinous components in the tumors, named as partial mixed MBC with less than 50% of mucinous components, main mixed MBC where the mucinous component accounted for 50% to 90%, and pure MBC with more than 90% of mucinous components...
April 23, 2017: Zhonghua Zhong Liu za Zhi [Chinese Journal of Oncology]
https://www.readbyqxmd.com/read/28550661/-progression-of-diagnosis-and-treatment-for-adenosquamous-lung-carcinoma
#3
W J Zhao, X Wang, K W Ma
Adenosquamous lung carcinoma (ASC) is an uncommon entity of the primary lung cancer, which is mixed by adenocarcinoma and squamous carcinoma cells. ASC not only possesses the malignant biological characteristics of adenocarcinoma and squamous cell carcinoma, but also exhibits special clinical features, such as the higher malignant degree and poorer prognosis. This paper is aimed to elaborate the research process of the pathological origin of ASC, the application of different diagnostic methods in ASC, various therapeutic strategies and its associated prognosis so as to help to develop the clinical strategies of ASC...
April 23, 2017: Zhonghua Zhong Liu za Zhi [Chinese Journal of Oncology]
https://www.readbyqxmd.com/read/28550417/motivational-interviewing-for-workers-with-disabling-musculoskeletal-disorders-results-of-a-cluster-randomized-control-trial
#4
Joanne Park, Shaniff Esmail, Fahreen Rayani, Colleen M Norris, Douglas P Gross
Purpose Although functional restoration programs appear effective in assisting injured workers to return-to-work (RTW) after a work related musculoskeletal (MSK) disorder, the addition of Motivational Interviewing (MI) to these programs may result in higher RTW. Methods We conducted a cluster randomized controlled trial with claimants attending an occupational rehabilitation facility from November 17, 2014 to June 30, 2015. Six clinicians provided MI in addition to the standard functional restoration program and formed an intervention group...
May 26, 2017: Journal of Occupational Rehabilitation
https://www.readbyqxmd.com/read/28550407/enhanced-antimicrobial-and-anticancer-properties-of-zno-and-tio2-nanocomposites
#5
C H Shilpa Chakra, V Rajendar, K Venkateswara Rao, Mirgender Kumar
The study describes the antibacterial and anticancer activities of a nanocomposite prepared by mixing zinc oxide and titanium dioxide nanoparticles. The particle mixtures were analyzed by X-ray diffraction, Field emission scanning electron microscopy, transmission electron microscopy, Fourier transform infrared spectroscopy, and dynamic light scattering techniques. Thus, analyzed samples were subject to disc diffusion method at various concentrations to analyze their antibacterial activities against two Gram-positive and two Gram-negative bacteria...
June 2017: 3 Biotech
https://www.readbyqxmd.com/read/28550379/a-mixed-methods-exploration-of-the-needs-of-people-living-with-hiv-plwh-enrolled-in-access-to-care-a-national-hiv-linkage-retention-and-re-engagement-in-medical-care-program
#6
C Maulsby, B Enobun, D S Batey, K M Jain, M Riordan, M Werner, D R Holtgrave
Competing needs pose barriers to engagement in HIV medical care. Mixed methods were used to explore and describe the needs of participants enrolled in Access to Care, a national HIV linkage, retention and re-engagement in care (LRC) program that served people living with HIV who knew their status but were not engaged in care. When asked to prioritize their most urgent needs, participants reported housing or shelter (31%), HIV medical services (24%), and employment (8%). When we assessed the HIV continuum of care by needs status, we found no significant differences in linkage, retention, or viral suppression between participants with and without basic needs...
May 26, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/28549928/speed-mentoring-an-innovative-method-to-meet-the-needs-of-the-young-surgeon
#7
Rebecca C Britt, Amy N Hildreth, Shannon N Acker, Nicolas J Mouawad, Joshua Mammen, Jacob Moalem
OBJECTIVE: Speed mentoring has recently been used by several medical organizations as a strategy to establish mentoring relationships, which are felt to be critically important in the development of the surgeon. This study assesses a surgical speed-mentoring program at the 2015 American College of Surgeons (ACS) Clinical Congress. DESIGN: A steering committee designed the speed-mentoring program to match 60 ACS Resident and Associate Society mentees with a mix of junior and senior leadership of ACS...
May 23, 2017: Journal of Surgical Education
https://www.readbyqxmd.com/read/28549609/development-and-validation-of-cf-medication-beliefs-questionnaire-a-mixed-methods-approach
#8
Michelle N Eakin, Shang-En Chung, Jessica Hoehn, Belinda Borrelli, Devin Rand-Giovannetti, Kristin A Riekert
BACKGROUND: Beliefs about medication have been associated with adherence in other diseases but there are no existing disease-specific medication beliefs questionnaires for CF. This mixed-methods validated the Cystic Fibrosis Medication Belief Questionnaire (CF-MBQ), based on social cognitive theory. METHODS: Based on previous research, items were developed for five domains: motivation, self-efficacy, perceived importance, and decisional balance to take or miss medications...
May 23, 2017: Journal of Cystic Fibrosis: Official Journal of the European Cystic Fibrosis Society
https://www.readbyqxmd.com/read/28549480/improving-the-appropriateness-of-antipsychotic-prescribing-in-nursing-homes-a-mixed-methods-process-evaluation-of-an-academic-detailing-intervention
#9
L Desveaux, M Saragosa, J Rogers, L Bevan, H Loshak, A Moser, S Feldman, L Regier, L Jeffs, N M Ivers
BACKGROUND: In 2014, nursing home administration and government officials were facing increasing public and media scrutiny around the variation of antipsychotic medication (APM) prescribing across Ontario nursing homes. In response, policy makers partnered to test an academic detailing (AD) intervention to address appropriate prescribing of APM in nursing homes in a cluster-randomized trial. This mixed-methods study aimed to explore how and why the AD intervention may have resulted in changes in the nursing home context...
May 26, 2017: Implementation Science: IS
https://www.readbyqxmd.com/read/28549471/the-shared-health-appointments-and-reciprocal-enhanced-support-shares-study-study-protocol-for-a-randomized-trial
#10
Michele Heisler, Jennifer Burgess, Jeffrey Cass, John F Chardos, Alexander B Guirguis, Sean M Jeffery, Lorrie A Strohecker, Adam S Tremblay, Wen-Chih Wu, Donna M Zulman
BACKGROUND: Diabetes shared medical appointments (SMAs) and reciprocal peer support programs have been found in efficacy trials to help adults with diabetes improve their self-management and achieve short-term gains in clinical and patient-centered outcomes. In order to translate this evidence to system-level interventions, there is a need for large-scale, pragmatic trials that examine the effectiveness, implementation, and costs of SMAs and reciprocal peer support across diverse settings...
May 26, 2017: Trials
https://www.readbyqxmd.com/read/28549386/newly-developed-dilute-russell-s-viper-venom-reagents-for-lupus-anticoagulant-detection-with-improved-specificity
#11
G W Moore, M Peyrafitte, C Dunois, J Amiral
Background Dilute Russell's viper venom time (dRVVT) is indispensible in lupus anticoagulant (LA) detection yet commercial reagents from different suppliers perform variably, no gold standard assays exist and therapeutic anticoagulation interference is problematic. Objective The objective of this study was to compare a new formulation dRVVT with two currently available dRVVTs. Materials and methods Life Diagnostics (LD) dRVVT and Stago PTT-LA were routinely used for lupus anticoagulant detection, plus Taipan snake venom time/ecarin time (TSVT/ET) for patients on warfarin or rivaroxaban...
January 1, 2017: Lupus
https://www.readbyqxmd.com/read/28549382/is-remote-health-different-to-rural-health
#12
John Wakerman, Lisa Bourke, John S Humphreys, Judy Taylor
INTRODUCTION: The study identifies the differences between rural health and remote health and describes key distinctive characteristics of remote health. METHODS: The study used a mixed method approach of interviews and questionnaires (utilising a Likert scale) with expert stakeholders in rural health and remote health. A total of 45 interviews were conducted with experts selected from every state and territory of Australia. Of these, 41 also completed a questionnaire, of which 21 respondents were female, 20 identified predominantly as academics while six, five and five indicated that they worked in policy, advocacy and as a practitioner, respectively...
April 2017: Rural and Remote Health
https://www.readbyqxmd.com/read/28549326/electrochemical-decolorization-of-methyl-red-by-ruo2-iro2-tio2-electrode-and-biodegradation-with-pseudomonas-stutzeri-mn1-and-acinetobacter-baumannii-mn3-an-integrated-approach
#13
Kuppusamy Sathishkumar, Sivaji Sathiyaraj, Punniyakotti Parthipan, Agrawal Akhil, Kadarkarai Murugan, Aruliah Rajasekar
Textile effluent consists of enormous quantities of toxic dyes, which are being discharged into natural aqueous system and thus contaminate the water quality. Hence it is important to develop an eco-friendly and cost effective technology to treat the dyes contaminated wastewater. In this research, an integrated approach of electrochemical oxidation (EO) and biodegradation process (BP) was studied of methyl red (MR) dye. In EO, RuO2-IrO2-TiO2 is used as anode and titanium mesh electrode as cathode. This was followed by BP of the treated EO effluent...
May 15, 2017: Chemosphere
https://www.readbyqxmd.com/read/28549316/method-for-assessment-of-stormwater-treatment-facilities-synthetic-road-runoff-addition-including-micro-pollutants-and-tracer
#14
Karin Cederkvist, Marina B Jensen, Peter E Holm
Stormwater treatment facilities (STFs) are becoming increasingly widespread but knowledge on their performance is limited. This is due to difficulties in obtaining representative samples during storm events and documenting removal of the broad range of contaminants found in stormwater runoff. This paper presents a method to evaluate STFs by addition of synthetic runoff with representative concentrations of contaminant species, including the use of tracer for correction of removal rates for losses not caused by the STF...
May 23, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28549183/pain-assessment-recommendations-for-women-made-by-women-a-mixed-methods-study
#15
Geoff P Bostick, Bruce D Dick, Mary Wood, Barbara Luckhurst, Julie Tschofen, Timothy W Wideman
Objective.:  To quantitatively describe women's priorities for pain assessment and qualitatively explain unique features of women's pain experiences. Design.:  Mixed-methods study that included a three-round Delphi study followed by in-depth interviews. Setting. : Clinical research study. Participants.:  Twenty-three women with chronic pain recruited from three women's pain treatment facilities and one interdisciplinary chronic pain clinic...
May 26, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/28548835/rapid-deposition-of-uniform-polydopamine-coatings-on-nanoparticle-surfaces-with-controllable-thickness
#16
Nazar Orishchin, Cameron C Crane, Matthew Brownell, Tengjiao Wang, Samuel Jenkins, Min Zou, Arun Nair, Jingyi Chen
Polydopamine is a bioinspired, versatile material that can adhere to bulk and nanoscale surfaces made of disparate materials to improve their physical and chemical properties in many applications. The typical methods to coat polydopamine on the nanoparticle substrates usually take several hours to a day. This work successfully applies a dispersion method to form a controllable, uniform coating on a nanoparticle surface within minutes. Using plasmonic Ag nanoparticles as a substrate, the coating thickness can be monitored using a spectroscopic method based on the extinction peak shifts of the Ag nanoparticles...
May 26, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28548682/arthrotomy-based-pre-clinical-models-of-particle-induced-osteolysis-a-systematic-review
#17
REVIEW
Meghan M Moran, Brittany M Wilson, Ryan D Ross, Amarjit S Virdi, D Rick Sumner
We completed a systematic literature review of in vivo animal models that use arthrotomy-based methods to study particle-induced peri-implant osteolysis. The purpose of the review was to characterize the models developed to date, to determine the questions addressed, to assess scientific rigor and transparency and to identify gaps in knowledge. We probed three literature databases (Medline, Embase and Scopus) and found 77 manuscripts that fit the search parameters. In the most recent 10 years, researchers mainly used rat and mouse models, whereas in the previous 20 years large animal, canine and rabbit models were more common...
May 26, 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/28548595/effect-of-treatment-modality-on-in-hospital-outcome-in-patients-with-subarachnoid-hemorrhage-a-nationwide-study-in-japan-j-aspect-study
#18
Ryota Kurogi, Akiko Kada, Kunihiro Nishimura, Satoru Kamitani, Ataru Nishimura, Tetsuro Sayama, Jyoji Nakagawara, Kazunori Toyoda, Kuniaki Ogasawara, Junichi Ono, Yoshiaki Shiokawa, Toru Aruga, Shigeru Miyachi, Izumi Nagata, Shinya Matsuda, Shinichi Yoshimura, Kazuo Okuchi, Akifumi Suzuki, Fumiaki Nakamura, Daisuke Onozuka, Akihito Hagihara, Koji Iihara
OBJECTIVE Although heterogeneity in patient outcomes following subarachnoid hemorrhage (SAH) has been observed across different centers, the relative merits of clipping and coiling for SAH remain unknown. The authors sought to compare the patient outcomes between these therapeutic modalities using a large nationwide discharge database encompassing hospitals with different comprehensive stroke center (CSC) capabilities. METHODS They analyzed data from 5214 patients with SAH (clipping 3624, coiling 1590) who had been urgently hospitalized at 393 institutions in Japan in the period from April 2012 to March 2013...
May 26, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28548520/oxysulfide-lialso-a-lithium-superionic-conductor-from-first-principles
#19
Xuelong Wang, Ruijuan Xiao, Hong Li, Liquan Chen
Through first-principles calculations and crystal structure prediction techniques, we identify a new layered oxysulfide LiAlSO in orthorhombic structure as a novel lithium superionic conductor. Two kinds of stacking sequences of layers of AlS_{2}O_{2} are found in different temperature ranges. Phonon and molecular dynamics simulations verify their dynamic stabilities, and wide band gaps up to 5.6 eV are found by electronic structure calculations. The lithium migration energy barrier simulations reveal the collective interstitial-host ion "kick-off" hopping mode with barriers lower than 50 meV as the dominating conduction mechanism for LiAlSO, indicating it to be a promising solid-state electrolyte in lithium secondary batteries with fast ionic conductivity and a wide electrochemical window...
May 12, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28547781/moms-growing-together-piloting-action-methods-and-expressive-arts-in-a-therapeutic-group-for-teen-mothers
#20
Lee SmithBattle, Chutima Chantamit-O-Pas, Patricia Freed, Dorcas McLaughlin, Joanne K Schneider
PURPOSE: The purpose of this pilot study was to test the safety, acceptability, feasibility, and effectiveness of Moms Growing Together (MGT), an intervention to prevent and reduce psychological distress in teen mothers. STUDY DESIGN AND METHODS: A mixed method design was used. The primary outcomes were reported satisfaction with MGT (acceptance); successful recruitment and retention of teen mothers (feasibility); and prevention or reduction of psychological distress (safety and effectiveness)...
May 26, 2017: Journal of Child and Adolescent Psychiatric Nursing
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