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https://www.readbyqxmd.com/read/28214327/improved-exposure-estimation-in-soil-screening-and-clean-up-criteria-for-volatile-organic-chemicals
#1
George E DeVaull
Soil clean-up criteria define acceptable concentrations of organic chemical constituents for exposed humans. These criteria sum the estimated soil exposure over multiple pathways. Assumptions for ingestion, dermal contact, and dust exposure generally presume a chemical persists in surface soils at a constant concentration level for the entire exposure duration. For volatile chemicals this is an unrealistic assumption. A calculation method is presented for surficial soil criteria which include volatile depletion of chemical for these uptake pathways...
February 18, 2017: Integrated Environmental Assessment and Management
https://www.readbyqxmd.com/read/28213541/accurate-quantification-of-laminarin-in-marine-organic-matter-with-enzymes-from-marine-microbes
#2
Stefan Becker, André Scheffel, Martin F Polz, Jan-Hendrik Hehemann
Marine algae produce varieties of glycans, which fulfill diverse biological functions and fuel the carbon and energy demand of heterotrophic microbes. A common approach to analyze marine organic matter uses acid to hydrolyze its glycans into measurable monosaccharides. These, however, may derive from different glycans that are built with the same monosaccharides, hence this approach does not distinguish between glycans in natural samples. Here we use enzymes to selectively digest and thereby quantify laminarin in particulate organic matter...
February 17, 2017: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/28213300/experiences-of-stigma-and-discrimination-faced-by-family-caregivers-of-people-with-schizophrenia-in-india
#3
Mirja Koschorke, R Padmavati, Shuba Kumar, Alex Cohen, Helen A Weiss, Sudipto Chatterjee, Jesina Pereira, Smita Naik, Sujit John, Hamid Dabholkar, Madhumitha Balaji, Animish Chavan, Mathew Varghese, R Thara, Vikram Patel, Graham Thornicroft
Stigma associated with schizophrenia significantly affects family caregivers, yet few studies have examined the nature and determinants of family stigma and its relationship to their knowledge about the condition. This paper describes the experiences and determinants of stigma reported by the primary caregivers of people living with schizophrenia (PLS) in India. The study used mixed methods and was nested in a randomised controlled trial of community care for people with schizophrenia. Between November 2009 and October 2010, data on caregiver stigma and functional outcomes were collected from a sample of 282 PLS-caregiver dyads...
February 1, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28213265/magnetic-mixed-hemimicelles-dispersive-solid-phase-extraction-based-on-ionic-liquid-coated-attapulgite-polyaniline-polypyrrole-fe3o4-nanocomposites-for-determination-of-acaricides-in-fruit-juice-prior-to-high-performance-liquid-chromatography-diode-array-detection
#4
Xiaoling Yang, Kexin Qiao, Fang Liu, Xiaoling Wu, Miyi Yang, Jing Li, Haixiang Gao, Sanbing Zhang, Wenfeng Zhou, Runhua Lu
In this research, a novel method using magnetic mixed hemimicelles dispersive solid-phase extraction (MMHDSPE) based on C16mimBr-coated attapulgite/polyaniline-polypyrrole/Fe3O4 (ATP/PANI-PPY/Fe3O4) nanocomposites were investigated for enrichment and separation of three acaricides in fruit juice. In this method, we combined the simplicity and speed of dispersive solid-phase extraction, the advantages of mixed hemimicelles and the facility of the phase separation of the magnetic nanoparticles to develop a simple, rapid, sensitive, and effective method for detecting target analytes from the juice samples...
May 1, 2017: Talanta
https://www.readbyqxmd.com/read/28213253/sensitive-kinetic-catalytic-spectrophotometric-method-for-cobalt-determination-using-a-chip-coupled-to-a-multisyringe-flow-injection-analysis-system
#5
Fatima Zohra Abouhiat, Camelia Henríquez, Farida El Yousfi, Víctor Cerdà
The development of an automated kinetic-catalytic spectrophotometric method for cobalt determination is presented. The method is based on the catalytic effect of Co in the oxidation of hydroxybenzoic acid by H2O2 in basic media. The method has been automated using a multisyringe flow injection system coupled to a monolithic flow conduit called chip (chip-MSFIA). All reagents and sample are simultaneously propelled into the chip to achieve an efficient mixing. The reaction product is monitored at 482nm. The reaction takes place very fast at room temperature, thus the fixed-time method is applied to quantify Co concentration in samples...
May 1, 2017: Talanta
https://www.readbyqxmd.com/read/28213236/the-extraction-of-uranium-using-graphene-aerogel-loading-organic-solution
#6
Mumei Chen, Zheng Li, Jihao Li, Jingye Li, Qingnuan Li, Lan Zhang
A new approach for uranium extraction employing graphene aerogel (GA) as a skeleton loading organic solution (GA-LOS) is proposed and investigated. Firstly, the GA with super-hydrophobicity and high organic solution absorption capacity was fabricated by one-step reduction and self-assembly of graphene oxide with ethylenediamine. By adsorbing Tri-n-butyl phosphate (TBP)/n-dodecane solution to prepare GA-LOS, the extraction of U(VI) from nitric acid medium using GA-LOS was investigated and compared with conventional solvent extraction...
May 1, 2017: Talanta
https://www.readbyqxmd.com/read/28213208/a-novel-and-sensitive-fluorescence-sensor-for-glutathione-detection-by-controlling-the-surface-passivation-degree-of-carbon-quantum-dots
#7
REVIEW
Jiahong Pan, Zengyao Zheng, Jianying Yang, Yaoyu Wu, Fushen Lu, Yaowen Chen, Wenhua Gao
A novel fluorescence sensor based on controlling the surface passivation degree of carbon quantum dots (CQDs) was developed for glutathione (GSH) detection. First, we found that the fluorescence intensity of the CQDs which was obtained by directly pyrolyzing citric acid would increased largely after the surface passivation treatment by 1-ethyl-3-(3-dimethylaminopropyl)-carbodiimide (EDC). In the light of this phenomenon, we designed a simple, rapid and selective fluorescence sensor based on the surface passivated CQDs...
May 1, 2017: Talanta
https://www.readbyqxmd.com/read/28213153/critical-thinking-instruction-and-technology-enhanced-learning-from-the-student-perspective-a-mixed-methods-research-study
#8
Ruth Swart
Critical thinking is acclaimed as a valuable asset for graduates from higher education programs. Technology has advanced in quantity and quality; recognized as a requirement of 21st century learners. A mixed methods research study was undertaken, examining undergraduate nursing student engagement with critical thinking instruction, platformed on two technology-enhanced learning environments: a classroom response system face-to-face in-class and an online discussion forum out-of-class. The Community of Inquiry framed the study capturing constructivist collaborative inquiry to support learning, and facilitate critical thinking capability...
February 4, 2017: Nurse Education in Practice
https://www.readbyqxmd.com/read/28213151/automatic-method-for-estimation-of-in-situ-effective-contact-angle-from-x-ray-micro-tomography-images-of-two-phase-flow-in-porous-media
#9
Alessio Scanziani, Kamaljit Singh, Martin J Blunt, Alberto Guadagnini
Multiphase flow in porous media is strongly influenced by the wettability of the system, which affects the arrangement of the interfaces of different phases residing in the pores. We present a method for estimating the effective contact angle, which quantifies the wettability and controls the local capillary pressure within the complex pore space of natural rock samples, based on the physical constraint of constant curvature of the interface between two fluids. This algorithm is able to extract a large number of measurements from a single rock core, resulting in a characteristic distribution of effective in situ contact angle for the system, that is modelled as a truncated Gaussian probability density distribution...
February 8, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28213092/prediction-of-thyroid-c-cell-carcinogenicity-after-chronic-administration-of-glp1-r-agonists-in-rodents
#10
Willem van den Brink, Annette Emerenciana, Francesco Bellanti, Oscar Della Pasqua, Jan Willem van der Laan
Increased incidence of C-cell carcinogenicity has been observed for glucagon-like-protein-1 receptor (GLP-1r) agonists in rodents. It is suggested that the duration of exposure is an indicator of carcinogenic potential in rodents of the different products on the market. Furthermore, the role of GLP-1-related mechanisms in the induction of C-cell carcinogenicity has gained increased attention by regulatory agencies. This study proposes an integrative pharmacokinetic/pharmacodynamic (PKPD) framework to identify explanatory factors and characterize differences in carcinogenic potential of the GLP-1r agonist products...
February 14, 2017: Toxicology and Applied Pharmacology
https://www.readbyqxmd.com/read/28213086/comparison-of-protocols-for-the-analysis-of-type-1-porcine-reproductive-and-respiratory-syndrome-virus-by-rt-pcr-using-oral-fluids
#11
Elisa Gibert, Gerard Martín-Valls, Enric Mateu
The detection of porcine reproductive and respiratory syndrome virus (PRRSV) in oral fluids (OF) by quantitative real-time polymerase chain reaction (qRT-PCR) is gaining increasing popularity. However, the different steps leading to a result have not been extensively evaluated. The aim of the present study was to examine the effect on the performance of qRT-PCR with different sampling materials, conditions of storage of the OF, the need for centrifuging OF, as well as to compare RNA extraction methods and PCR mixes...
February 14, 2017: Journal of Virological Methods
https://www.readbyqxmd.com/read/28212910/-to-see-with-my-own-eyes-experiences-of-family-visits-during-phase-1-recovery
#12
M Cecilia Wendler, Katherine Smith, Wanda Ellenburg, Rita Gill, Lea Anderson, Kim Spiegel-Thayer
PURPOSE: Long separations are a characteristic of the day of surgery, keeping patients and their family members waiting and apart. At a time of high vulnerability, these separations can cause anxiety and worry. The purpose of this study was to identify the outcomes and experiences of patients and family members who engaged in a 5- to 10-minute supervised family visit during phase I postanesthesia recovery. DESIGN: This was a descriptive, single-group, mixed-methods study...
February 2017: Journal of Perianesthesia Nursing: Official Journal of the American Society of PeriAnesthesia Nurses
https://www.readbyqxmd.com/read/28212667/assessing-the-interruption-of-the-transmission-of-human-helminths-with-mass-drug-administration-alone-optimizing-the-design-of-cluster-randomized-trials
#13
Roy Anderson, Sam Farrell, Hugo Turner, Judd Walson, Christl A Donnelly, James Truscott
BACKGROUND: A method is outlined for the use of an individual-based stochastic model of parasite transmission dynamics to assess different designs for a cluster randomized trial in which mass drug administration (MDA) is employed in attempts to eliminate the transmission of soil-transmitted helminths (STH) in defined geographic locations. The hypothesis to be tested is: Can MDA alone interrupt the transmission of STH species in defined settings? Clustering is at a village level and the choice of clusters of villages is stratified by transmission intensity (low, medium and high) and parasite species mix (either Ascaris, Trichuris or hookworm dominant)...
February 17, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28212657/pharmacists-views-and-reported-practices-in-relation-to-a-new-generic-drug-substitution-policy-in-lebanon-a-mixed-methods-study
#14
Fadi El-Jardali, Racha Fadlallah, Rami Z Morsi, Nour Hemadi, Mounir Al-Gibbawi, Magda Haj, Suzan Khalil, Youssef Saklawi, Diana Jamal, Elie A Akl
BACKGROUND: Governments in both developed and developing countries have adopted generic drug substitution policies to decrease pharmaceutical expenditures and improve access to medicine. In August 2015, the Ministry of Public Health (MOPH) in Lebanon introduced generic drug substitution and a unified medical prescription form as policy instruments to promote generic drug use. The objective of this exploratory study was to examine the attitudes of community pharmacists and the reported practices in relation to the implementation of the new generic drug substitution policy...
February 17, 2017: Implementation Science: IS
https://www.readbyqxmd.com/read/28212652/a-mixed-methods-feasibility-study-of-nicotine-assisted-smoking-reduction-programmes-delivered-by-community-pharmacists-the-redpharm-study
#15
Amanda Farley, Sarah Tearne, Taina Taskila, Rachel H Williams, Susan Mackaskill, Jean-Francois Etter, Paul Aveyard
BACKGROUND: Pivotal trials have established that, among people who have no immediate intention to quit smoking, nicotine replacement therapy (NRT) helps people reduce and eventually stop smoking. The prime aim of this trial was to investigate the feasibility of implementing such a programme in community pharmacies. In addition, we investigated the effectiveness of providing behavioural support compared with self-help methods and of shorter compared with standard length reduction programmes...
February 17, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28212490/vitamin-e-succinate-grafted-chitosan-oligosaccharide-rgd-conjugated-tpgs-mixed-micelles-loaded-with-paclitaxel-for-u87mg-tumor-therapy
#16
Yanzuo Chen, Shu Feng, Wenchao Liu, Zeting Yuan, Peihao Yin, Feng Gao
The poor therapeutic efficacy of hydrophobic chemotherapeutic drugs is an intrinsic limitation to successful chemotherapy. In the present study, a multi-task delivery system based on arginine-glycine-aspartic acid peptide (RGD) decorated vitamin E succinate (VES)-grafted-chitosan oligosaccharide (CSO)/RGD-conjugated D-alpha-tocopheryl polyethylene glycol 1000 succinate (TPGS-RGD) mixed micelles (VeC/T-RGD MM) was first prepared for targeted delivery of paclitaxel (PTX), a hydrophobic anticancer drug, to improve the efficacy of U87MG tumor therapy...
February 17, 2017: Molecular Pharmaceutics
https://www.readbyqxmd.com/read/28212481/-workplace-bullying-during-specialty-training-in-a-pediatric-hospital-in-mexico-a-little-noticed-phenomenon
#17
Ana Carolina Sepúlveda-Vildósola, Alma Rebeca Mota-Nova, Germán Enrique Fajardo-Dolci, L Isabel Reyes-Lagunes
BACKGROUND: Workplace bullying (WB) is a hostile or intimidating behavior that is practiced against workers and has a negative impact on health, job performance, and the learning process. The objective was to research WB magnitude and its associated factors in Mexico. METHODS: Mixed method study. A survey was designed and administered to all the residents in a pediatric hospital in Mexico who agreed to participate. The survey was divided in two sections: a) resident self-reported events of workplace bullying and associated factors, b) situations and factors of abuse were interrogated in a targeted manner...
2017: Revista Médica del Instituto Mexicano del Seguro Social
https://www.readbyqxmd.com/read/28212131/psychometric-properties-of-a-new-instrument-for-assessing-irrational-thoughts-in-burn-victims-scale-of-irrational-thoughts-after-burn-injuries
#18
Zahra Zare, Homayoun Sadeghi-Bazargani, Fatemeh Ranjbar, Diana Stark Ekman, Mostafa Farahbakhsh, Hemmat Maghsoudi, Robert Ekman, Farideh Nasiri
The objective of this study was to develop and evaluate a scale for assessing irrational thoughts among burned patients. The present study was mixed (qualitative-methodologic) which was performed in several stages such as investigating similar or related scales, interviewing with patients and psychologists. Content validity was calculated by modified KAPPA basis on relevance and clarity. The reliability of the scale was measured using internal consistency and the test-retest method. To determine the construct validity, exploratory factor analysis approach using maximum likelihood extraction with varimax rotation was conducted...
February 9, 2017: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://www.readbyqxmd.com/read/28212116/developing-a-community-of-practice-for-hiv-care-supporting-knowledge-translation-in-a-regional-training-initiative
#19
Donna M Gallagher, Lisa R Hirschhorn, Laura S Lorenz, Priyatam Piya
INTRODUCTION: Ensuring knowledgeable, skilled HIV providers is challenged by rapid advances in the field, diversity of patients and providers, and the need to retain experienced providers while training new providers. These challenges highlight the need for education strategies, including training and clinical consultation to support translation of new knowledge to practice. New England AIDS Education and Training Center (NEAETC) provides a range of educational modalities including academic peer detailing and distance support to HIV providers in six states...
February 15, 2017: Journal of Continuing Education in the Health Professions
https://www.readbyqxmd.com/read/28211824/impact-of-the-brain-injury-family-intervention-bifi-training-on-rehabilitation-providers-a-mixed-methods-study
#20
Cara Meixner, Cynthia R O'Donoghue, Vesna Hart
BACKGROUND: The psychological impact of TBI is vast, leading to adverse effects on survivors and their caregivers. Unhealthy family functioning may be mitigated by therapeutic strategies, particularly interdisciplinary family systems approaches like the well-documented Brain Injury Family Intervention (BIFI). Little is known about the experience of providers who offer such interventions. OBJECTIVE: This mixed method study aims to demonstrate that a structured three-day training on the BIFI protocol improves providers' knowledge and confidence in working with survivors and families, and that this outcome is sustainable...
February 15, 2017: NeuroRehabilitation
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