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https://www.readbyqxmd.com/read/29239855/experimental-verification-of-stopping-power-prediction-from-single-and-dual-energy-computed-tomography-in-biological-tissues
#1
Christian Möhler, Tom Russ, Patrick Wohlfahrt, Alina Elter, Armin Runz, Christian Richter, Steffen Greilich
An experimental setup for consecutive measurement of ion and x-ray absorption in tissue or other materials is introduced. With this setup using a 3D-printed sample container, the reference stopping-power ratio (SPR) of materials can be measured with an uncertainty of below 0.1%. A total of 65 porcine and bovine tissue samples were prepared for measurement, comprising five samples each of 13 tissue types representing about 80% of the total body mass (three different muscle and fatty tissues, liver, kidney, brain, heart, blood, lung and bone)...
December 14, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/29232300/three-dimensional-printing-of-life-like-models-for-simulation-and-training-of-minimally-invasive-cardiac-surgery
#2
Toshiyuki Yamada, Motohiko Osako, Tomoya Uchimuro, Ryogen Yoon, Toshiaki Morikawa, Maki Sugimoto, Hisao Suda, Hideyuki Shimizu
OBJECTIVE: As the use of minimally invasive surgery in cardiothoracic surgery increases, so does the need for simulation and training. We developed a heart model for simulation and training of minimally invasive cardiac surgery, particularly minimally invasive mitral valve repair using our new three-dimensional printing system. METHODS: Digital imaging and communication in medicine data from patient computed tomography, three-dimensional computer-aided design, and three-dimensional printing helped create replicas of the heart and thoracic cavity...
December 7, 2017: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
https://www.readbyqxmd.com/read/29231093/the-utility-of-simulation-in-the-management-of-patients-with-congenital-heart-disease-past-present-and-future
#3
Ali Subat, Andrew Goldberg, Samuel Demaria, Daniel Katz
Significant advancements have been made in the diagnosis and management of congenital heart disease (CHD). As a result, a higher percentage of these patients are surviving to adulthood. Despite this improvement in management, these patients remain at higher risk of morbidity and mortality, particularly in the perioperative setting. One new area of interest in these patients is the implementation of simulation-based medical education. Simulation has demonstrated various benefits across high-acuity scenarios encountered in the hospital...
December 1, 2017: Seminars in Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/29223704/decellularized-heart-ecm-hydrogel-using-supercritical-carbon-dioxide-for-improved-angiogenesis
#4
Yoojin Seo, Youngmee Jung, Soo Hyun Kim
Initial angiogenesis within the first 3 days is critical for healing ischemic diseases such as myocardial infarction. Recently, decellularized extracellular matrix (dECM) has been reported to provide tissue-derived ECM components and can be used as a scaffold for cell delivery for angiogenesis in tissue engineering. Decellularization by various detergents such as sodium dodecyl sulfate (SDS) and triton X-100 can remove the cell nuclei in tissue organs. However, this leads to ECM structure denaturation, decreased presence of various ECM proteins and cytokines, and loss of mechanical properties...
December 6, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/29186007/anatomically-realistic-ultrasound-phantoms-using-gel-wax-with-3d-printed-moulds
#5
Efthymios Maneas, Wenfeng Xia, Daniil I Nikitichev, Batol Daher, Maniragav Manimaran, Rui Yen J Wong, Chia-Wei Chang, Benyamin Rahmani, Claudio Capelli, Silvia Schievano, Gaetano Burriesci, Sebastien Ourselin, Anna L David, Malcolm Finlay, Simeon J West, Tom Vercauteren, Adrien E Desjardins
Here we describe methods for creating tissue-mimicking ultrasound phantoms based on patient anatomy using a soft material called gel wax. To recreate acoustically realistic tissue properties, two additives to gel wax were considered: paraffin wax to increase acoustic attenuation, and solid glass spheres to increase backscattering. The frequency dependence of ultrasound attenuation was well described with a power law over the measured range of 3 to 10 MHz. With the addition of paraffin wax in concentrations of 0 to 8 w/w%, attenuation varied from 0...
November 29, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/29181795/comparison-of-3d-echocardiogram-derived-3d-printed-valve-models-to-molded-models-for-simulated-repair-of-pediatric-atrioventricular-valves
#6
Adam B Scanlan, Alex V Nguyen, Anna Ilina, Andras Lasso, Linnea Cripe, Anusha Jegatheeswaran, Elizabeth Silvestro, Francis X McGowan, Christopher E Mascio, Stephanie Fuller, Thomas L Spray, Meryl S Cohen, Gabor Fichtinger, Matthew A Jolley
Mastering the technical skills required to perform pediatric cardiac valve surgery is challenging in part due to limited opportunity for practice. Transformation of 3D echocardiographic (echo) images of congenitally abnormal heart valves to realistic physical models could allow patient-specific simulation of surgical valve repair. We compared materials, processes, and costs for 3D printing and molding of patient-specific models for visualization and surgical simulation of congenitally abnormal heart valves...
November 27, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/29161072/sexual-assertiveness-skills-and-sexual-decision-making-in-adolescent-girls-randomized-controlled-trial-of-an-online-program
#7
Laura Widman, Carol E Golin, Kristyn Kamke, Jeni L Burnette, Mitchell J Prinstein
OBJECTIVES: To evaluate the efficacy of an interactive, Web-based sexual health program (Health Education and Relationship Training [HEART]) for developing sexual assertiveness skills and enhancing sexual decision-making in adolescent girls. METHODS: Participants were 222 tenth-grade girls (mean age = 15.2; 38% White, 29% Hispanic, 25% Black) in the Southeastern United States who were randomized in fall 2015 to the HEART intervention or an attention-matched control...
November 21, 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/29158165/cardiac-3d-printing-for-better-understanding-of-congenital-heart-disease
#8
Khaled Hadeed, Philippe Acar, Yves Dulac, Fabio Cuttone, Xavier Alacoque, Clément Karsenty
No abstract text is available yet for this article.
November 17, 2017: Archives of Cardiovascular Diseases
https://www.readbyqxmd.com/read/29089896/a-comparative-study-on-fetal-heart-rates-estimated-from-fetal-phonography-and-cardiotocography
#9
Emad A Ibrahim, Shamsa Al Awar, Zuhur H Balayah, Leontios J Hadjileontiadis, Ahsan H Khandoker
The aim of this study is to investigate that fetal heart rates (fHR) extracted from fetal phonocardiography (fPCG) could convey similar information of fHR from cardiotocography (CTG). Four-channel fPCG sensors made of low cost (<$1) ceramic piezo vibration sensor within 3D-printed casings were used to collect abdominal phonogram signals from 20 pregnant mothers (>34 weeks of gestation). A novel multi-lag covariance matrix-based eigenvalue decomposition technique was used to separate maternal breathing, fetal heart sounds (fHS) and maternal heart sounds (mHS) from abdominal phonogram signals...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/29067708/preliminary-study-of-the-application-of-transthoracic-echocardiography-guided-three-dimensional-printing-for-the-assessment-of-structural-heart-disease
#10
Yanbo Zhu, Jianshi Liu, Lianqun Wang, Xin Guan, Yongjuan Luo, Jie Geng, Qingguo Geng, Yunjia Lin, Lixia Zhang, Xixue Li, Yaping Lu
OBJECTIVE: To investigate the feasibility and diagnostic value of a preoperative transthoracic echocardiography-guided three-dimensional printed model (TTE-guided 3DPM) for the assessment of structural heart disease (SHD). METHODS: Fourty-four patients underwent cardiac surgery at Tianjin Chest Hospital. The patients were preoperatively assessed using TTE-guided 3DPM, which was compared to conventional three-dimensional transthoracic echocardiography (3DTTE) along with direct intraoperative findings, which were considered the "gold standard...
October 25, 2017: Echocardiography
https://www.readbyqxmd.com/read/29060433/ctg-analyzer-a-graphical-user-interface-for-cardiotocography
#11
Agnese Sbrollini, Angela Agostinelli, Luca Burattini, Micaela Morettini, Francesco Di Nardo, Sandro Fioretti, Laura Burattini
Cardiotocography (CTG) is the most commonly used test for establishing the good health of the fetus during pregnancy and labor. CTG consists in the recording of fetal heart rate (FHR; bpm) and maternal uterine contractions (UC; mmHg). FHR is characterized by baseline, baseline variability, tachycardia, bradycardia, acceleration and decelerations. Instead, UC signal is characterized by presence of contractions and contractions period. Such parameters are usually evaluated by visual inspection. However, visual analysis of CTG recordings has a well-demonstrated poor reproducibility, due to the complexity of physiological phenomena affecting fetal heart rhythm and being related to clinician's experience...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29034225/the-perception-of-a-three-dimensional-printed-heart-model-from-the-perspective-of-different-stakeholders-a-complex-case-of-truncus-arteriosus
#12
Giovanni Biglino, Sarah Moharem-Elgamal, Matthew Lee, Robert Tulloh, Massimo Caputo
The case of an 11-year-old male patient with truncus arteriosus is presented. The patient has a right aortic arch, a repaired truncus arteriosus, pulmonary artery stenosis, as well as conduit stenosis, with a complex surgical plan being discussed. In order to gather additional insight into the patient's anatomy prior to the surgery and to facilitate communication with the patient's parents, a three-dimensional (3D) model of his heart and main vessels was created from computed tomography data. Feedback was collected from different stakeholders...
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/29030328/studying-acute-coronary-syndrome-through-the-world-wide-web-experiences-and-lessons
#13
Angelo A Alonzo
This study details my viewpoint on the experiences, lessons, and assessments of conducting a national study on care-seeking behavior for heart attack in the United States utilizing the World Wide Web. The Yale Heart Study (YHS) was funded by the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health (NIH). Grounded on two prior studies, the YHS combined a Web-based interview survey instrument; ads placed on the Internet; flyers and posters in public libraries, senior centers, and rehabilitation centers; information on chat rooms; a viral marketing strategy; and print ads to attract potential participants to share their heart attack experiences...
October 13, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/29025029/ct-coronary-imaging-a-fast-evolving-world
#14
Prabhakar Rajiah, Suhny Abbara
Computed tomography (CT) has become an important modality in the evaluation of coronary artery disease (CAD). The tremendous technological advances in CT in the last two decades has made it possible to obtain high quality images of coronary arteries with high spatial and temporal resolutions. Multiple trials have confirmed the accuracy of CT compared to invasive catheter angiography. CT is also able to evaluate beyond the lumen in characterizing and quantifying atherosclerotic plaques, including evaluation of high risk features...
September 4, 2017: QJM: Monthly Journal of the Association of Physicians
https://www.readbyqxmd.com/read/29018639/managing-heart-failure-at-home-with-point-of-care-diagnostics
#15
Paul R Degregory, Jansen Tapia, Tammy Wong, Jo Villa, Ian Richards, Richard M Crooks
The objective of this paper is development of an inexpensive point-of-care sensor for detecting the primary heart failure marker peptide, NT-proBNP. The device technology is based on an antibody sandwich assay, but with three innovative aspects. First, chemical amplification is carried out via oxidation of silver nanoparticles (NPs) attached to signaling antibodies rather than by enzymatic amplification. The electrochemical method is faster and eliminates the need for long-term storage of enzymes. Second, the antibody sandwich is formed on mobile magnetic beads...
2017: IEEE Journal of Translational Engineering in Health and Medicine
https://www.readbyqxmd.com/read/28977423/three-dimensional-printed-models-for-surgical-planning-of-complex-congenital-heart-defects-an-international-multicentre-study
#16
Israel Valverde, Gorka Gomez-Ciriza, Tarique Hussain, Cristina Suarez-Mejias, Maria N Velasco-Forte, Nicholas Byrne, Antonio Ordoñez, Antonio Gonzalez-Calle, David Anderson, Mark G Hazekamp, Arno A W Roest, Jose Rivas-Gonzalez, Sergio Uribe, Issam El-Rassi, John Simpson, Owen Miller, Enrique Ruiz, Ignacio Zabala, Ana Mendez, Begoña Manso, Pastora Gallego, Freddy Prada, Massimiliano Cantinotti, Lamia Ait-Ali, Carlos Merino, Andrew Parry, Nancy Poirier, Gerald Greil, Reza Razavi, Tomas Gomez-Cia, Amir-Reza Hosseinpour
OBJECTIVES: To evaluate the impact of 3D printed models (3D models) on surgical planning in complex congenital heart disease (CHD). METHODS: A prospective case-crossover study involving 10 international centres and 40 patients with complex CHD (median age 3 years, range 1 month-34 years) was conducted. Magnetic resonance imaging and computed tomography were used to acquire and segment the 3D cardiovascular anatomy. Models were fabricated by fused deposition modelling of polyurethane filament, and dimensions were compared with medical images...
December 1, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28976740/3d-printed-pericardium-hydrogels-to-promote-wound-healing-in-vascular-applications
#17
Laura G Bracaglia, Michael Messina, Shira Winston, Che-Ying Kuo, Max Lerman, John P Fisher
Vascular grafts that can support total replacement and maintenance by the body of the injured vessel would improve outcomes of major surgical reconstructions. Building scaffolds using components of the native vessel can encourage biological recognition by native cells as well as mimic mechanical characteristics of the native vessel. Evidence is emerging that incorporating predetermined building-blocks into a tissue engineering scaffold may oversimplify the environment and ignore critical structures and binding sites essential to development at the implant...
October 16, 2017: Biomacromolecules
https://www.readbyqxmd.com/read/28971093/antimicrobial-peptides-in-biomedical-device-manufacturing
#18
REVIEW
Martijn Riool, Anna de Breij, Jan W Drijfhout, Peter H Nibbering, Sebastian A J Zaat
Over the past decades the use of medical devices, such as catheters, artificial heart valves, prosthetic joints, and other implants, has grown significantly. Despite continuous improvements in device design, surgical procedures, and wound care, biomaterial-associated infections (BAI) are still a major problem in modern medicine. Conventional antibiotic treatment often fails due to the low levels of antibiotic at the site of infection. The presence of biofilms on the biomaterial and/or the multidrug-resistant phenotype of the bacteria further impair the efficacy of antibiotic treatment...
2017: Frontiers in Chemistry
https://www.readbyqxmd.com/read/28948646/a-practical-guide-to-cardiovascular-3d-printing-in-clinical-practice-overview-and-examples
#19
Islam Abudayyeh, Brent Gordon, Mohammad M Ansari, Kenneth Jutzy, Liset Stoletniy, Anthony Hilliard
The advent of more advanced 3D image processing, reconstruction, and a variety of three-dimensional (3D) printing technologies using different materials has made rapid and fairly affordable anatomically accurate models much more achievable. These models show great promise in facilitating procedural and surgical planning for complex congenital and structural heart disease. Refinements in 3D printing technology lend itself to advanced applications in the fields of bio-printing, hemodynamic modeling, and implantable devices...
September 25, 2017: Journal of Interventional Cardiology
https://www.readbyqxmd.com/read/28939646/design-and-validation-of-a-tissue-bath-3d-printed-with-pla-for-optically-mapping-suspended-whole-heart-preparations
#20
Michael William Entz, David Ryan King, Steven Poelzing
With the sudden increase in affordable manufacturing technologies, the relationship between experimentalists and the designing process for laboratory equipment is rapidly changing. While experimentalists are still dependent on engineers and manufacturers for precision electrical, mechanical, and optical equipment, it has become a realistic option for in house manufacturing of other laboratory equipment with less precise design requirements. This is possible due to decreasing costs and increasing functionality of desktop 3D printers and 3D design software...
September 22, 2017: American Journal of Physiology. Heart and Circulatory Physiology
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