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Byung Yong Kang, Joon Seol Bae, Ki Tae Kim, Jae Hyoun Kim, Jung Hee Shin, Chung Choo Lee
OBJECTIVE: To investigate the role of the apolipoprotein(a) [Apo(a)] gene in predicting essential hypertension in the Korean population, we undertook a case-control study using the TTTTA repeat and the Met/Thr polymorphisms of the Apo(a) gene. METHODS: The study subjects consisted of 74 essential hypertensives and 211 normotensive individuals. For polymorphism analysis, DNA was amplified by polymerase chain reaction (PCR). In the case of the Met/Thr polymorphism, amplified PCR products were digested with the restriction enzyme Kspl...
April 2002: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
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