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https://www.readbyqxmd.com/read/29774647/effect-of-the-fetal-movement-count-on-maternal-fetal-attachment
#1
Esra Güney, Tuba Uçar
AIM: This study aimed to determine the effect of fetal movement counting on maternal-fetal attachment. METHODS: This study was a randomized controlled trial, conducted with experimental and control groups, each including 55 pregnant women from six family health centers in the Malatya Province, located in the east of Turkey. The data were collected by using a Personal Information Form and the Maternal Antenatal Attachment Scale. Training for fetal movement counting was provided to the experimental group...
May 17, 2018: Japan Journal of Nursing Science: JJNS
https://www.readbyqxmd.com/read/29774319/impact-of-personality-traits-anxiety-depression-and-hopelessness-levels-on-quality-of-life-in-the-patients-with-breast-cancer
#2
Filiz İzci, Dauren Sarsanov, Zeynep İyigün Erdogan, Ahmet Serkan İlgün, Esra Çelebi, Gül Alço, Nazmiye Kocaman, Çetin Ordu, Alper Öztürk, Tomris Duymaz, Kezban Nur Pilavcı, Filiz Elbüken, Filiz Ağaçayak, Fatma Aktepe, Gizem Ünveren, Gözdem Özdem, Yeşim Eralp, Vahit Özmen
Objective: The aim of this study was to investigate the impacts of personality traits, anxiety, depression and hopelessness levels on quality of life in the patients with breast cancer. Materials and methods: The study was performed on 90 patients diagnosed with breast cancer and 90 healthy women. Sociodemographic and Clinical Data Collection Form designed by us, Beck Hopelessness Scale (BHS), Beck Anxiety Scale (BAS), Beck Depression Scale (BDS), Eysenck Personality Inventory (EPI) and Quality of Life Scale-Short Form (SF-36) were administered to patients and to control group...
April 2018: European Journal of Breast Health
https://www.readbyqxmd.com/read/29774109/sik2-attenuates-proliferation-and-survival-of-breast-cancer-cells-with-simultaneous-perturbation-of-mapk-and-pi3k-akt-pathways
#3
Neslihan Zohrap, Özge Saatci, Burcak Ozes, Ipek Coban, Hasan Murat Atay, Esra Battaloglu, Özgür Şahin, Kuyas Bugra
Salt Inducible Kinase2 (SIK2) has been shown to contribute to tumorigenesis in multiple tumor types in a dichotomous manner. However, little is known about its contribution to breast malignancies. Here, we report SIK2 as a potential tumor suppressor in breast cancer whose expression was reduced in tumor tissues and breast cancer cell lines compared to normal counterparts. In vitro loss- and gain-of-function experiments combined with xenograft studies demonstrated that SIK2-mediated attenuation of proliferation and survival of breast cancer cells with parallel inhibition of both Ras/Erk and PI3K/Akt pathways...
April 24, 2018: Oncotarget
https://www.readbyqxmd.com/read/29772948/a-new-isoflavane-4-ol-derivative-from-melilotus-officinalis-l-pall
#4
Mert Ilhan, Zulfiqar Ali, Ikhlas A Khan, Esra Küpeli Akkol
A new isoflavane derivative, melilofficinaside together with seven other metabolites including coumarin, uridine, methyl-α-d-fructofuranoside, and flavonoid glucosides were isolated from the aerial parts of Melilotus officinalis (L.) Pall.
May 18, 2018: Natural Product Research
https://www.readbyqxmd.com/read/29772415/highly-efficient-polymer-supported-monodisperse-ruthenium-nickel-nanocomposites-for-dehydrocoupling-of-dimethylamine-borane
#5
Betul Sen, Esra Kuyuldar, Buse Demirkan, Tugba Onal Okyay, Aysun Şavk, Fatih Sen
In the present study, highly effective and reusable monodisperse ruthenium-nickel (Ru-Ni) nanomaterials supported on poly(N-vinyl-2-pyrrolidone) (Ru-Ni@PVP) were synthesized (3.51 ± 0.38 nm) by a facile sodium-hydroxide-assisted reduction method; Ru and Ni reduction in PVP solution was accomplished. The prepared nanocomposites were characterized by TEM, HRTEM, XRD, and XPS and performed as a catalyst for dehydrocoupling of dimethylamine-borane (DMAB). It was found that Ru-Ni nanomaterials are one of the most active catalysts at low concentrations and temperature for dehydrocoupling of DMAB...
May 14, 2018: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/29771613/determinants-of-mental-disorders-in-syrian-refugees-in-turkey-versus-internally-displaced-persons-in-syria
#6
Sidika Tekeli-Yesil, Esra Isik, Yesim Unal, Fuad Aljomaa Almossa, Hande Konsuk Unlu, Ahmet Tamer Aker
OBJECTIVES: To compare frequencies of some mental health disorders between Syrian refugees living in Turkey and internally displaced persons in Syria, and to identify factors associated with posttraumatic stress disorder and major depressive disorder. METHODS: We carried out a field survey in May 2017 among 540 internally displaced persons in Syria and refugees in Turkey. RESULTS: The study revealed that mental disorders were highly prevalent in both populations...
May 17, 2018: American Journal of Public Health
https://www.readbyqxmd.com/read/29770834/advances-in-drug-discovery-for-human-beta-cell-regeneration
#7
REVIEW
Esra Karakose, Courtney Ackeifi, Peng Wang, Andrew F Stewart
The numbers of insulin-secreting pancreatic beta cells are reduced in people with type 1 and type 2 diabetes. Driving beta cell regeneration in the pancreases of people with diabetes would be an attractive approach to reversing diabetes. While adult human beta cells have long been believed to be terminally differentiated and, therefore, irreversibly quiescent, it has become clear over recent years that this is not true. More specifically, both candidate and unbiased high-throughput screen approaches have revealed several classes of molecules that are clearly able to induce human beta cell proliferation...
May 16, 2018: Diabetologia
https://www.readbyqxmd.com/read/29769720/rspo2-inhibition-of-rnf43-and-znrf3-governs-limb-development-independently-of-lgr4-5-6
#8
Emmanuelle Szenker-Ravi, Umut Altunoglu, Marc Leushacke, Célia Bosso-Lefèvre, Muznah Khatoo, Hong Thi Tran, Thomas Naert, Rivka Noelanders, Amin Hajamohideen, Claire Beneteau, Sergio B de Sousa, Birsen Karaman, Xenia Latypova, Seher Başaran, Esra Börklü Yücel, Thong Teck Tan, Lena Vlaeminck, Shalini S Nayak, Anju Shukla, Katta Mohan Girisha, Cédric Le Caignec, Natalia Soshnikova, Zehra Oya Uyguner, Kris Vleminckx, Nick Barker, Hülya Kayserili, Bruno Reversade
The four R-spondin secreted ligands (RSPO1-RSPO4) act via their cognate LGR4, LGR5 and LGR6 receptors to amplify WNT signalling1-3 . Here we report an allelic series of recessive RSPO2 mutations in humans that cause tetra-amelia syndrome, which is characterized by lung aplasia and a total absence of the four limbs. Functional studies revealed impaired binding to the LGR4/5/6 receptors and the RNF43 and ZNRF3 transmembrane ligases, and reduced WNT potentiation, which correlated with allele severity. Unexpectedly, however, the triple and ubiquitous knockout of Lgr4, Lgr5 and Lgr6 in mice did not recapitulate the known Rspo2 or Rspo3 loss-of-function phenotypes...
May 16, 2018: Nature
https://www.readbyqxmd.com/read/29764480/a-stepped-approach-for-the-management-of-symptomatic-internal-derangement-of-the-temporomandibular-joint
#9
Candan Efeoglu, Aylin Sipahi Calis, Huseyin Koca, Esra Yuksel
BACKGROUND: Internal derangement is the clinical and pathological condition of disc displacement of the temporomandibular joint. Management of these cases involve conservative and surgical treatment options. Minimally invasive surgical procedures namely arthrocentesis and arthroscopy are promising techniques in the management of internal derangement. However patient selection algorithms, indications for minimally invasive procedures and details of the techniques should be further studied for safe and cost effective management of these cases...
May 15, 2018: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/29757148/mild-encephalitis-encephalopathy-with-a-reversible-splenial-lesion-in-children
#10
Adalet Elçin Yıldız, Hülya Maraş Genç, Esra Gürkaş, Havva Akmaz Ünlü, İbrahim Halil Öncel, Alev Güven
PURPOSE: We aimed to present clinical and radiologic characteristics of mild encephalitis/encephalopathy with a reversible splenial lesion (MERS) in children. METHODS: Eight children (5 boys and 3 girls; median age, 5.9 years; age range, 8 months to 14.1 years) diagnosed with MERS between September 2015 and June 2017 were included in the study. We reviewed the patient's data, including demographic characteristics, prodromal and neurologic symptoms, neurologic examination, magnetic resonance imaging and electroencephalography findings, laboratory findings, treatment, and prognosis...
March 2018: Diagnostic and Interventional Radiology: Official Journal of the Turkish Society of Radiology
https://www.readbyqxmd.com/read/29756115/severe-decrease-in-spo-2-and-methemoglobinemia-following-subareolar-isosulfan-blue-administration-and-clinical-relevance
#11
Esra Yüksel, Dilek Duman, Levent Yeniay, Sezgin Ulukaya
The level of axillary lymph node involvement in breast cancer is a critical decision factor for adjuvant therapy and the most important indicator of prognosis and survival. Sentinel lymph node biopsy is a minimally invasive technique with low morbidity in axillary staging of breast cancer. Radiocolloid substances (Technetium-99m) and/or blue dyes such as methylene blue or isosulfan blue are used during sentinel lymph node biopsy. Isosulfan blue stain is frequently used in sentinel lymph node biopsy and rarely causes complications...
2018: Turkish Journal of Surgery
https://www.readbyqxmd.com/read/29749833/neurotransmitter-receptor-genotypes-associated-with-mental-and-behavioral-disorders
#12
Ekrem Varoglu, Adil Seytanoglu, Esra Asilmaz, Bahar Taneri
AIM: Investigation of association studies within the field of mental and behavioral disorders is of value given their complex molecular etiology including epistatic interactions of multiple genes with small effects. MATERIALS & METHODS: Utilizing biomedical text mining, associations are uncovered for all mental and behavioral conditions listed in Diagnostic and Statistical Manual of Mental Disorders Text Revision. Specifically, a computational pipeline is designed to retrieve neurotransmitter receptor variations from biomedical literature with a text mining approach, where unique polymorphisms are also mined...
July 2017: Personalized Medicine
https://www.readbyqxmd.com/read/29746438/hemophagocytic-lymphohistiocytosis-associated-with-visceral-leishmaniasis
#13
Nihal Özdemir, Başak Koç, Esra Arslantaş, Işik Odaman Al, Çiğdem Kelleci, Ezgi Pasli Uysalol, Cengiz Bayram, Ali Ayçiçek
This is the report of a 2-year-old boy who presented with fever, cytopenia, and splenomegaly. The patient was diagnosed with hemophagocytic lymphohistiocytosis (HLH) and treated with HLH-2004 protocol. Repeated bone marrow aspiration showed amastigotes on follow-up. In endemic countries, visceral leishmaniasis should be considered in the differential diagnosis to avoid chemotherapy toxicity.
May 9, 2018: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/29746218/effect-of-an-innovative-technology-active-warming-and-passive-warming-on-unplanned-hypothermia-during-perioperative-period-a-clinical-trial
#14
Ganime Esra Soysal, Arzu İlçe, Mehmet Hayri Erkol
Patients are at risk for unplanned hypothermia during the perioperative period due to many reasons, including anesthesia, low room temperature, cold intravenous fluid, and blood transfusion. This study was conducted to examine the effect of active and passive warming methods applied in patients during the perioperative period on unplanned hypothermia. This study is a case-control type study. The population of this study is composed of the patients hospitalized in surgical clinic and undergone abdominal region-related operations...
May 10, 2018: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/29744249/the-effect-of-anaesthetic-techniques-on-maternal-and-cord-blood-brain-derived-neurotrophic-factor-levels
#15
Mehmet Aksoy, Ayşe Nur Aksoy, Ali Ahıskalıoğlu, İlker İnce, Esra Laloğlu, Ayşenur Dostbil, Mine Gürsaç Çelik
Objective: Brain-derived neurotrophic factor (BDNF), a member of neurotrophins, plays a critical role in neuronal tissue. In this study, the effects of spinal or general anaesthesia on cord and maternal peripheral blood BDNF and malondialdehyde (MDA) levels were investigated in patients undergoing elective caesarean section. Methods: Eighty patients with term pregnancy were included. General anaesthesia was induced with intravenous (IV) propofol 2 mg kg-1 in the general anaesthesia group (n=36)...
April 2018: Turkish Journal of Anaesthesiology and Reanimation
https://www.readbyqxmd.com/read/29741671/similar-subclinical-enthesitis-in-celiac-and-inflammatory-bowel-diseases-by-ultrasound-suggests-a-gut-enthesis-axis-independent-of-spondyloarthropathy-spectrum
#16
Sibel Bakirci Ureyen, Cengiz Karacaer, Bilal Toka, Zeynep Erturk, Ahmet Tarik Eminler, Muhammed Kaya, Koray Tascilar, Ali Tamer, Ihsan Uslan, Esra Kurum, Dennis McGonagle, Sibel Zehra Aydin
Objective: Higher subclinical enthesitis on US has been reported in IBD and celiac disease, separately. The objective of this study was to compare IBD and celiac disease for enthesitis on US. Higher enthesitis scores in IBD compared with celiac disease would support a shared pathogenic mechanism between IBD and spondyloarthritis, whereas similar scores may suggest a general impact of gut inflammation on the enthesis. Methods: Patients with IBD, celiac disease and healthy controls (HCs) were recruited and 12 entheses were scanned by US, blind to the diagnosis and clinical assessment...
May 8, 2018: Rheumatology
https://www.readbyqxmd.com/read/29739133/increased-neutrophil-lymphocyte-and-platelet-lymphocyte-ratios-in-male-heroin-addicts-a-prospective-controlled-study
#17
Erdinc Cıcek, Başak Demırel, Ismet Esra Cıcek, Aslı Seda Kıraç, Ibrahim Eren
Objective: The neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) are markers that can determine the presence of systemic inflammatory response. In this study, we examined the NLR and PLR levels in patients with heroin dependence compared to healthy controls. Methods: The study sample included 90 male patients with heroin dependence aged 18 to 45 years and 60 healthy subjects who had similar socio-demographic characteristics as the patient group...
May 31, 2018: Clinical Psychopharmacology and Neuroscience: the Official Scientific Journal of the Korean College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/29737876/microrna-221-222-expression-in-atherosclerotic-coronary-artery-plaque-and-peripheral-blood
#18
Aslıhan Esra Bildirici, Serdal Arslan, Nil Özbilüm Şahin, Öcal Berkan, Osman Beton, Mehmet Birhan Yılmaz
BACKGROUND: Atherosclerosis is a disease of the arterial wall with predilection to some sites on others. MicroRNAs (miRNAs) are a class of the non-coding RNAs regulating the target gene expression at post-transcriptional level. Different miRNAs were found at distinct stages of plaque development and expression of miRNAs' might play an important role in the local behaviour of atherosclerotic plaques. OBJECTIVE: We aimed to investigate and compare mirR-221/222 expression levels in tissues and in circulation in patients with and without overt atherosclerosis...
May 8, 2018: Biomarkers: Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals
https://www.readbyqxmd.com/read/29735084/physical-and-chemical-stability-of-anthocyanin-rich-black-carrot-extract-loaded-liposomes-during-storage
#19
Burcu Guldiken, Monika Gibis, Dilek Boyacioglu, Esra Capanoglu, Jochen Weiss
In this study, the protection effect of black carrot extract on the stability of liposomes during storage was evaluated. The physical and chemical stability of the extract (0.4% w/w) including extract-loaded liposomes with various lecithin content (1%, 2%, and 4% w/w) were demonstrated. Z-average particle diameter and zeta potentials of liposomes were evaluated before and after 21 days of storage. The particle diameter of the samples was found to be lower than 50 nm after storage and no statistical change was determined (p < 0...
June 2018: Food Research International
https://www.readbyqxmd.com/read/29730875/how-effective-are-efficiency-studies-an-evaluation-in-the-context-of-cognitive-behavioral-therapies
#20
Esra Güven, Gözde Gökçe
The consensus view is that the main goal of a psychotherapy approach is to make changes in dysfunctional attitudes and behaviors. Therapeutic effectiveness, which is defined as "the establishment of causality between the intervention and the emergent changes in target behavior, symptom, or disorder," has been examined via studies of therapeutic effectiveness. In this review, we aimed to evaluate the therapeutic efficacy and/or ef- fectiveness studies in terms of their METHODS, results, and approaches...
2018: Türk Psikiyatri Dergisi, Turkish Journal of Psychiatry
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