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https://www.readbyqxmd.com/read/28098108/the-relationship-between-mean-platelet-volume-and-neutrophil-lymphocyte-ratio-with-inflammation-and-proteinuria-in-chronic-kidney-disease
#1
Gulay Yilmaz, Can Sevinc, Sedat Ustundag, Yasemin Coskun Yavuz, Tuba Hacıbekiroglu, Esra Hatipoglu, Mehmet Baysal
Atherosclerosis, which develops as a result of inflammation, is the most important cause of morbidity and mortality in chronic kidney disease (CKD). In this study, we investigated the relationship of mean platelet volume (MPV) and neutrophil/lymphocyte ratio (NLR) with inflammation and proteinuria in patients with CKD Stage 3-4. Healthy individuals who applied to nephrology clinic for checkup purposes acted as controls. Fifty-three patients and 30 healthy controls were included in the study. Patients with diabetes mellitus, active infection, malignancy, and coronary artery disease were excluded from the study...
January 2017: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/28097644/erratum-to-eur-j-ophthalmol-2002-12-1-1-4-and-eur-j-ophthalmol-2015-25-5-437-442
#2
(no author information available yet)
Erratum To: Eur J Ophthalmol. 2002 Jan-Feb;12(1):1-4. doi: 10.5301/EJO.2008.799. Prevalence of astigmatism among students in northern Greece. A.T. Mandalos, D.K. Peios, T.A. Mavrakanas, V.A. Golias, K.G. Megalou, K.A. Delidou, A.C. Gregoriadou, B.C. Katsougiannopoulos PMID: 11936436 [PubMed - indexed for MEDLINE]We inform our readers that in the author list the full name of one author (T.A. Mavracanas) was published incorrectly. We supply the correct author listing and apologize to the readers. Eur J Ophthalmol...
December 29, 2016: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/28095352/the-relationship-of-rel-proto-oncogene-to-pathobiology-and-chemoresistance-in-follicular-and-transformed-follicular-lymphoma
#3
Xiaozhou Hu, Esra Baytak, Jinnan Li, Burcu Akman, Kaan Okay, Genfu Hu, Anna Scuto, Wenyan Zhang, Can Küçük
Follicular lymphoma (FL) is a common type of indolent lymphoma that occasionally transforms to more aggressive B-cell lymphomas. These transformed follicular lymphomas (tFL) are often associated with chemoresistance whose mechanisms are currently unknown. REL, a proto-oncogene located on frequently amplified 2p16.1-p15 locus, promotes tumorigenesis in many cancer types through deregulation of the NF-κB pathway; however, its role in FL pathobiology or chemoresistance has not been addressed. Here, we evaluated REL gene copy number by q-PCR on FFPE FL tumor samples, and observed REL amplification in 30...
January 9, 2017: Leukemia Research
https://www.readbyqxmd.com/read/28092684/biallelic-mutations-in-the-3-exonuclease-toe1-cause-pontocerebellar-hypoplasia-and-uncover-a-role-in-snrna-processing
#4
Rea M Lardelli, Ashleigh E Schaffer, Veerle R C Eggens, Maha S Zaki, Stephanie Grainger, Shashank Sathe, Eric L Van Nostrand, Zinayida Schlachetzki, Basak Rosti, Naiara Akizu, Eric Scott, Jennifer L Silhavy, Laura Dean Heckman, Rasim Ozgur Rosti, Esra Dikoglu, Anne Gregor, Alicia Guemez-Gamboa, Damir Musaev, Rohit Mande, Ari Widjaja, Tim L Shaw, Sebastian Markmiller, Isaac Marin-Valencia, Justin H Davies, Linda de Meirleir, Hulya Kayserili, Umut Altunoglu, Mary Louise Freckmann, Linda Warwick, David Chitayat, Susan Blaser, Ahmet Okay Çağlayan, Kaya Bilguvar, Huseyin Per, Christina Fagerberg, Henrik T Christesen, Maria Kibaek, Kimberly A Aldinger, David Manchester, Naomichi Matsumoto, Kazuhiro Muramatsu, Hirotomo Saitsu, Masaaki Shiina, Kazuhiro Ogata, Nicola Foulds, William B Dobyns, Neil C Chi, David Traver, Luigina Spaccini, Stefania Maria Bova, Stacey B Gabriel, Murat Gunel, Enza Maria Valente, Marie-Cecile Nassogne, Eric J Bennett, Gene W Yeo, Frank Baas, Jens Lykke-Andersen, Joseph G Gleeson
Deadenylases are best known for degrading the poly(A) tail during mRNA decay. The deadenylase family has expanded throughout evolution and, in mammals, consists of 12 Mg(2+)-dependent 3'-end RNases with substrate specificity that is mostly unknown. Pontocerebellar hypoplasia type 7 (PCH7) is a unique recessive syndrome characterized by neurodegeneration and ambiguous genitalia. We studied 12 human families with PCH7, uncovering biallelic, loss-of-function mutations in TOE1, which encodes an unconventional deadenylase...
January 16, 2017: Nature Genetics
https://www.readbyqxmd.com/read/28092488/low-level-laser-therapy-in-enhancing-wound-healing-and-preserving-tissue-thickness-at-free-gingival-graft-donor-sites-a-randomized-controlled-clinical-study
#5
Gulbahar Ustaoglu, Esra Ercan, Mustafa Tunali
OBJECTIVE: The aim of this study was to determine the effects of low-level laser therapy (LLLT) on wound healing at free gingival graft (FGG) donor sites. MATERIALS AND METHODS: Forty patients requiring FGG were selected for this randomized, controlled, and double-blinded prospective clinical trial. The FGG donor sites were treated with LLLT and compared with an untreated control group. The Wound-Healing Index (WHI), tissue consistency, color match, and H2O2 bubbling test for the evaluation of complete wound epithelialization were recorded on the 3rd, 7th, 14th and 21st days...
January 12, 2017: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/28081467/oxidative-stress-and-mrna-expression-of-acetylcholinesterase-in-the-leukocytes-of-ischemic-patients
#6
Mesut Işık, Şükrü Beydemir, Aslan Yılmaz, Muhammet Emin Naldan, Hatice Esra Aslan, İlhami Gülçin
BACKGROUND: Pathogenesis of ischemic brain injury is occurred by crucial metabolic reasons. For instance, oxidative stress from free radical generation is causing to the thrombotic cerebrovascular stroke. In this case, the measurement of the oxidative stress is very important for a better understanding of the stroke pathophysiology. Because, the oxidative stress in stroke is generally assumed as one of the mechanisms taking part in neuronal damage. Thus, oxidative stress has a vital role in the cholinergic system...
January 9, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28080032/heteroprotein-complex-formation-of-bovine-lactoferrin-and-pea-protein-isolate-a-multiscale-structural-analysis
#7
Eda Adal, Amin Sadeghpour, Simon D A Connell, Michael Rappolt, Esra Ibanoglu, Anwesha Sarkar
Associative electrostatic interactions between two oppositely charged globular proteins, lactoferrin (LF) and pea protein isolate (PPI), the latter being a mixture of vicilin, legumin and convicilin, was studied with a specific PPI/ LF molar ratio at room temperature. Structural aspects of the electrostatic complexes probed at different length scales were investigated as a function of pH by means of different complementary techniques, namely with dynamic light scattering, small angle X-ray scattering (SAXS), turbidity measurements and atomic force microscopy (AFM)...
January 12, 2017: Biomacromolecules
https://www.readbyqxmd.com/read/28076563/influence-of-the-epiretinal-membrane-on-ranibizumab-therapy-outcomes-in-patients-with-diabetic-macular-edema
#8
Nimet Yesim Ercalik, Serhat Imamoglu, Esra Turkseven Kumral, Nursal Melda Yenerel, Handan Bardak, Yavuz Bardak
Purpose: To investigate the influence of the epiretinal membrane (ERM) on intravitreal ranibizumab (IVR) therapy for diabetic macular edema (DME). Methods: This retrospective study included 56 eyes of 48 patients with DME divided into two groups: the DME with ERM (study) and only DME (control) groups. Changes in the central macular thickness (CMT) and best-corrected visual acuity (BCVA) were evaluated. Results: In the study group, although the CMT was significantly reduced following the first injection (p<0...
November 2016: Arquivos Brasileiros de Oftalmologia
https://www.readbyqxmd.com/read/28076503/effect-of-s%C3%A4-lymar%C3%A4-n-on-ox%C3%A4-dat%C3%A4-ve-stress-and-l%C3%A4-ver-h%C3%A4-stopathology-%C3%A4-n-exper%C3%A4-mental-obstruct%C3%A4-ve-jaund%C3%A4-ce-model
#9
Ali Kemal Onalan, Salih Tuncal, Sibel Kilicoglu, Salih Celepli, Esra Durak, Bulent Kilicoglu, Erdinc Devrim, Aziz Mutlu Barlas, Kemal Kismet
PURPOSE: To investigate the effect of silymarin on oxidative stress and hepatic injury induced by obstructive jaundice in an experimental model. METHODS: Thirty Wistar-Albino type female rats were divided into 3 groups each including 10 rats. Only laparotomy was performed in group 1. Bile duct ligation was performed in group 2. In group 3, bile duct ligation was performed and orogastic silymarin 300 mg/kg/day dose was given for seven days. At the end of seven days, rats were sacrificed...
December 2016: Acta Cirúrgica Brasileira
https://www.readbyqxmd.com/read/28065478/a-comparison-of-the-open-reduction-internal-fixation-and-resection-arthroplasty-techniques-in-treatment-of-mason-type-3-radial-head-fractures
#10
Yunus Emre Akman, Erhan Sukur, Esra Circi, Osman Nuri Ozyalvac, Fatih Ozyer, Yusuf Ozturkmen
OBJECTIVE: The aim of this study was to retrospectively compare a series of patients surgically treated with ORIF or early resection arthroplasty due to isolated comminuted radial head fractures. METHODS: Between the years 2009 and 2013, 34 patients with isolated comminuted fractures of the radial head (Mason Type 3) had been operated (ORIF in 19 patients, resection arthroplasty in 15 patients). The mean age of the patients in the ORIF group was 38.5 years and 54 years in the resection group...
January 5, 2017: Acta Orthopaedica et Traumatologica Turcica
https://www.readbyqxmd.com/read/28058158/a-rare-cause-of-proptosis-in-childhood-langerhans-cell-histiocytosis
#11
Mustafa Vatansever, Esra Vatansever, Erdem Dinç, Ayça Sarı, Tuba Kara
A three-year-old male patient was admitted to the clinic with proptosis in his right eye. He had a history of fever with an unknown etiology. In examination, right proptosis was observed and an immobile mass was palpated at the lateral wall of the right orbita. Eye movement was unrestricted in all directions and anterior and posterior segment examination was normal in both eyes. On computed tomography, diffuse bone destruction and expansion was observed in the right orbital lateral wall and other cranial bones...
August 2016: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/28058149/surgical-indications-and-clinical-results-of-patients-with-exchanged-intraocular-lenses-in-a-tertiary-eye-hospital
#12
Sevim Kavuncu, Aslıhan Esra Omay, Mehmet Hakan Tırhış, Pelin Yılmazbaş
OBJECTIVES: To evaluate the demographics, surgical indications and clinical results of patients with repositioned or explanted intraocular lens (IOL) in a tertiary referral eye hospital. MATERIALS AND METHODS: Forty-eight eyes of 48 patients that underwent surgery to exchange or reposition the IOL at Ulucanlar Eye Training and Research Hospital between 2009 and 2013 were included in the study. Medical records of patients were evaluated for surgical indications, time elapsed since initial operation, preoperative and postoperative best corrected distance visual acuity and the presence of ocular disease...
August 2016: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/28052717/oncoplastic-surgery-volume-displacement-techniques-for-breast-conserving-surgery-in-patients-with-breast-cancer
#13
Gunay Gurleyik, Hikmet Karagulle, Esra Eris, Fugen Aker, Basak O Ustaalioglu
BACKGROUND: Surgical management of breast cancer has drastically changed. Breast-conserving surgery (BCS) has now become a commonly used method for its treatment. Oncoplastic techniques are widely applied with satisfactory aesthetic results. We evaluated the aesthetic and oncological outcomes of BCS with glandular tissue displacement techniques. METHODS: Seventy-five patients with invasive breast cancer were surgically treated by oncoplastic techniques. Preoperative evaluations, including breast and tumor size, localizations and features, were performed by physical examination, imaging methods, and histopathological analysis...
January 5, 2017: Acta Chirurgica Belgica
https://www.readbyqxmd.com/read/28044991/age-specific-frequencies-and-characteristics-of-ovarian-cysts-in-children-and-adolescents
#14
Hamdi Cihan Emeksiz, Okşan Derinöz, Esra Betül Akkoyun, Faruk Güçlü Pınalı, Aysun Bideci
OBJECTIVE: The aim of the present study was to document ovarian cyst frequency and characteristics, as well as distribution of these parameters with respect to age in children and adolescents. METHODS: We retrospectively analyzed the medical records of 1009 girls between the ages of 5-18 years who presented to pediatric emergency department with pelvic pain and therefore underwent pelvic ultrasound examination between June 2011 and May 2014. RESULTS: In total, 132 of 1009 girls (13...
December 30, 2016: Journal of Clinical Research in Pediatric Endocrinology
https://www.readbyqxmd.com/read/28043350/evaluation-of-changes-in-doppler-ultrasonography-indices-and-levels-of-maternal-serum-angiogenic-factors-throughout-pregnancy-in-ewes
#15
Özge Turna Yilmaz, Mehmet Can Gündüz, Gamze Evkuran Dal, Melih Uçmak, Zeynep Günay Uçmak, Esra Karaçam, Güven Kaşikçi, Mehmet Ragip Kiliçarslan
We evaluated the changes in the pulsatility index (PI) and resistance index (RI) of fetal and maternal vessels and maternal serum angiogenic factors throughout pregnancy in 20 Kivircik ewes. They were examined for pregnancy detection on Day 30 after mating. The PI and RI during the pregnancies were followed using Doppler ultrasonography (USG) of the uterine artery, umbilical artery, fetal aorta, and fetal vena cava. Doppler USG was performed every 15 days beginning from the 40th day after mating. Blood samples were collected every 15 days starting from the day of mating...
February 2017: Theriogenology
https://www.readbyqxmd.com/read/28041575/the-impact-of-major-depression-on-heart-rate-variability-and-endothelial-dysfunction-in-patients-with-stable-coronary-artery-disease
#16
Esra Aydin Sunbul, Murat Sunbul, Huseyin Gulec
BACKGROUND: Depression is an independent risk factor in cardiovascular diseases. Changes in the cardiac autonomic functions and pro-inflammatory processes are potential biological factors. Endothelial dysfunction plays an important role in the etiopathogenesis of atherosclerosis. Our objective was to evaluate the impact of major depression on heart rate variability and endothelial dysfunction in patients with stable CAD. METHODS: The study group included 65 CAD patients with a diagnosis of major depression and 54 CAD patients without major depression...
January 2017: General Hospital Psychiatry
https://www.readbyqxmd.com/read/28040237/-comparison-of-effectiveness-of-intubation-by-way-of-gum-elastic-bougie-and-intubating-laryngeal-mask-airway-in-endotracheal-intubation-of-patients-with-simulated-cervical-trauma
#17
Esra Yildiz Sut, Solmaz Gunal, Mehmet Akif Yazar, Bayazit Dikmen
PURPOSE: In this study, we evaluated the effectiveness of intubations by way of Gum Elastic Bougie and Intubating Laryngeal Mask Airway in endotracheal intubation of patients with simulated cervical trauma. METHOD: One hundred and thirty four patients were included in the study. All patients were placed cervical collar for a simulated cervical trauma. Patients were allocated randomly into three groups: Group NI (n=45) intubation with Macintosh laryngoscopy, Group GEB (n=45) intubation with Gum Elastic Bougie, and Group ILMA (n=44) intubation with Intubating Laryngeal Mask Airway...
December 28, 2016: Revista Brasileira de Anestesiologia
https://www.readbyqxmd.com/read/28040120/a-mixture-of-st-john-s-wort-and-sea-buckthorn-oils-regresses-endometriotic-implants-and-affects-the-levels-of-inflammatory-mediators-in-peritoneal-fluid-of-the-rat-a-surgically-induced-endometriosis-model
#18
Mert İlhan, İpek Süntar, Mürşide Ayşe Demirel, Erdem Yeşilada, Hikmet Keleş, Esra Küpeli Akkol
OBJECTIVE: Sea buckthorn (Hippophae rhamnoides L.) and St. John's wort (Hypericum perforatum L.) are used as an emmenagog and for the treatment of other gynecological disorders including uterus inflammation and endometriosis. The aim of the present study is to investigate the potential of a mixture of sea buckthorn and St. John's wort oils (HrHp oil) in the treatment of endometriosis. MATERIALS AND METHODS: The activity was assessed in surgically induced endometriosis in rats...
December 2016: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28039281/association-of-rate-dependent-conduction-block-between-eccentric-coronary-sinus-to-left-atrial-connections-with-inducible-atrial-fibrillation-and-flutter
#19
Dong Huang, Joseph E Marine, Jing-Bo Li, Tarek Zghaib, Esra Gucuk Ipek, Sunil Sinha, David D Spragg, Hiroshi Ashikaga, Ronald D Berger, Hugh Calkins, Saman Nazarian
BACKGROUND: We sought to describe the prevalence and variability of coronary sinus (CS) and left atrial (LA) myocardium connections, their susceptibility to rate-dependent conduction block, and association with atrial fibrillation (AF) and flutter induction. METHODS AND RESULTS: The study cohort included 30 consecutive AF patients (age 63.3±10.5 years, 63% male). Multipolar catheters were positioned in the CS, high right atrium (HRA), and LA parallel to and near the CS...
January 2017: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/28033104/micronuclei-and-other-nuclear-anomalies-in-buccal-epithelial-cells-of-children-with-chronic-kidney-disease
#20
Banu Aykanat, Gonca Cakmak Demircigil, Necla Buyan, Esra Baskin, Kaan Gulleroglu, Kibriya Fidan, Umut Selda Bayrakci, Aydin Dalgic, Hamdi Karakayali, Mehmet Haberal, Sema Burgaz
The objective of this study was to reveal the likely genomic instability in children with chronic kidney disease (CKD) using micronucleus (MN) assay on buccal epithelial cells (BEC). We investigated the frequencies of micronuclei and other nuclear anomalies, such as nuclear buds, binucleated cells, condensed chromatin, and karyorrhectic and pyknotic cells in BEC. Children with CKD were grouped as follows: children in the pre-dialysis (PreD) stage (N=17), children on regular haemodialysis (HD) (N=14), and children who have undergone transplantation (Tx) (N=17)...
December 1, 2016: Arhiv za Higijenu Rada i Toksikologiju
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