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Tethered Cord Syndrome

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https://www.readbyqxmd.com/read/27870788/prenatal-ultrasound-evaluation-of-the-position-of-conus-medullaris-for-the-diagnosis-of-tethered-cord-syndrome
#1
Shao-Zheng He, Guo-Rong Lv, Shun-Lan Liu, Jun-Xian Ruan
To determine the conus distance between the end of the conus medullaris and the distal end of the last vertebral body in healthy fetuses with various gestational ages using ultrasonography for its diagnostic value in tethered cord syndrome (TCS). This retrospective study included 540 healthy and 8 autopsy-confirmed TCS fetuses. Ultrasonographic measurement of the conus distance was performed when the fetus was in a prone position within the spine in the near field at 14 to 41 weeks of gestational age. Linear correlation analysis was performed to analyze the relationship between the conus distance and the gestational age, biparietal diameter, femur length, head circumference, and abdominal circumference...
December 2016: Ultrasound Quarterly
https://www.readbyqxmd.com/read/27861396/surgical-treatments-on-adult-tethered-cord-syndrome-a-retrospective-study
#2
Jun Gao, Xiangyi Kong, Zhimin Li, Tianyu Wang, Yongning Li
To investigate effects of surgical treatment on adult tethered cord syndrome (TCS).A retrospective analysis of 82 adult patients (17 male cases, 82% and 24 female cases, 59%) with TCS treated by surgery was conducted between March, 2005 and December, 2015, with an average age of 31.6 years and average disease course of 6.7 years. All the 82 cases of patients received nerve electrophysiology monitoring assisted microsurgery. After surgery, all patients were followed up for an average of 2.5 years. Surgical effects were evaluated according to Hoffman grading system...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27843691/co-existing-spinal-intradural-ependymal-cyst-and-sacral-tarlov-cyst-in-adult-onset-tethered-cord-syndrome-with-syringomyelia-case-report-and-literature-review
#3
Hamid H Rai, Muhammad F Khan, Syed Ather Enam, Imtiaz Hashmi
BACKGROUND: Synchronous spinal intradural ependymal cysts and sacral Tarlov cysts in adult onset tethered cord syndrome are extremely rare. CASE DESCRIPTION: A 23-year-old male presented with back pain radiating into both lower extremities, accompanied by acute onset of gait difficulty and sphincter dysfunction. Magnetic resonance imaging identified a low lying conus medullaris, syringomyelia with septations extending from T12 to S1, a tethered cord, and a thickened filum terminale with a sacral Tarlov cyst...
2016: Surgical Neurology International
https://www.readbyqxmd.com/read/27833778/magnetic-resonance-imaging-analysis-of-caudal-regression-syndrome-and-concomitant-anomalies-in-pediatric-patients
#4
Deb K Boruah, Dhaval D Dhingani, Sashidhar Achar, Arjun Prakash, Antony Augustine, Shantiranjan Sanyal, Manoj Gogoi, Kangkana Mahanta
OBJECTIVE: The aim of this study was to evaluate the magnetic resonance imaging (MRI) findings of caudal regression syndrome (CRS) and concomitant anomalies in pediatric patients. MATERIALS AND METHODS: A hospital-based cross-sectional retrospective study was conducted. The study group comprised 21 pediatric patients presenting to the Departments of Radiodiagnosis and Pediatric Surgery in a tertiary care hospital from May 2011 to April 2016. All patients were initially evaluated clinically followed by MRI...
2016: Journal of Clinical Imaging Science
https://www.readbyqxmd.com/read/27794580/think-of-the-conus-medullaris-at-the-time-of-diagnosis-of-fetal-sacral-agenesis
#5
Nicolas Mottet, Jelena Martinovic, Claire Baeza, Fabien Guimiot, Jean-Philippe Bault, Marie Cécile Aubry, Didier Riethmuller, Michel Zerah, Celia Cretolle, Alexandra Benachi
BACKGROUND: There is no precise prenatal indicator to refine an accurate prognosis in case of sacral agenesis and to define the diagnostic approach and outcome criteria in case of fetal sacral agenesis using 3 characteristics of the conus medullaris (CM): its position, its appearance, and associated spinal abnormalities. METHODS: Ten cases of prenatally diagnosed sacral agenesis were included between 1995 and 2014 after collating ultrasound findings and prenatal computed tomography data...
October 29, 2016: Fetal Diagnosis and Therapy
https://www.readbyqxmd.com/read/27790529/successful-pregnancy-outcome-in-an-operated-case-of-lipomeningomyocele-a-rare-case
#6
Vineet Vashistha Mishra, Sakshi Nanda, Rohina Aggarwal, Tanvir
Lipomeningomyocele is one of the types of occult spinal dysraphism associated with tethered cord syndrome, which is characterised by neurodeficit symptomatology due to stretch- induced functional disorder of the spinal cord with its caudal part attached by an in elastic tissue. There is stretching of conus medullaris and nerve roots due to disproportionate growth between vertebral column and spinal cord, resulting in various neurological deficits. Its incidence is approximately 1 in 4000 births in the USA, with a slightly higher female preponderance, although its true incidence is not known...
September 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27790325/surgical-outcome-of-children-and-adolescents-with-tethered-cord-syndrome
#7
Toshitaka Seki, Kazutoshi Hida, Shunsuke Yano, Toru Sasamori, Shuji Hamauch, Izumi Koyanagi, Kiyohiro Houkin
STUDY DESIGN: Retrospective cohort study. PURPOSE: To compare long-term results of surgery with the outcomes of symptomatic and asymptomatic tethered cord syndrome (TCS) in children and adolescents and to assess the surgery duration for those with TCS. OVERVIEW OF LITERATURE: Pediatric patients with TCS continue to pose significant diagnostic and management challenges. METHODS: We retrospectively analyzed the outcomes of 31 patients (16 males, 15 females) with TCS, including 21 with lumbosacral lipoma...
October 2016: Asian Spine Journal
https://www.readbyqxmd.com/read/27735228/duplicated-filum-terminale-in-non-split-cord-malformations-an-underrecognized-cause-for-treatment-failure-in-tethered-cord-syndrome
#8
Daniele Starnoni, John Michael Duff, Gopalakrishnan Chittur Viswanathan
CONTEXT: Anatomical variations of the filum terminale (FT) have been described in association with split cord malformations (SCM) but they appear to be a rare finding in its absence. We report the first case in literature of a duplicated FT in a patient presenting with tethered cord syndrome (TCS) without any radiological evidence of SCM. FINDINGS: A 47-year-old man presented with invalidating back pain radiating to both legs. Magnetic resonance imaging revealed an intradural dorsal lipoma in a low-lying conus...
October 13, 2016: Journal of Spinal Cord Medicine
https://www.readbyqxmd.com/read/27673095/poster-342-tethered-cord-syndrome-in-a-patient-with-40-year-history-of-spinal-cord-injury-a-case-report
#9
Arlene Lazaro, Miguel X Escalon, Mariam Zakhary
No abstract text is available yet for this article.
September 2016: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/27651783/association-between-chromosomal-aberration-of-cox8c-and-tethered-spinal-cord-syndrome-array-based-comparative-genomic-hybridization-analysis
#10
Qiu-Jiong Zhao, Shao-Cong Bai, Cheng Cheng, Ben-Zhang Tao, Le-Kai Wang, Shuang Liang, Ling Yin, Xing-Yi Hang, Ai-Jia Shang
Copy number variations have been found in patients with neural tube abnormalities. In this study, we performed genome-wide screening using high-resolution array-based comparative genomic hybridization in three children with tethered spinal cord syndrome and two healthy parents. Of eight copy number variations, four were non-polymorphic. These non-polymorphic copy number variations were associated with Angelman and Prader-Willi syndromes, and microcephaly. Gene function enrichment analysis revealed that COX8C, a gene associated with metabolic disorders of the nervous system, was located in the copy number variation region of Patient 1...
August 2016: Neural Regeneration Research
https://www.readbyqxmd.com/read/27593844/are-herniated-cerebellar-tonsils-the-main-culprit-of-chiari-malformation-type-i-symptoms-brainstem-compression-hypothesis-seems-to-be-re-elucidated-and-revised
#11
Mehmet Selcuki, Mesut Mete, Deniz Selcuki
AIM: The Chiari Malformation I (CM I) and tethered cord syndrome (TCS) are both congenital abnormalities whose mechanism are still not fully understood. Associaton of CM I and TCS have been reported only for a few times previously Material and Methods: This retrospective study includes 7 patients who were diagnosed with CM I and TCS managed by cutting of the filum terminale. RESULTS: The mean follow-up period was 21 months and 28 days. Although all patients were undergone untethering surgical procedure by cutting the filum terminale only, all patients reported significant early postsurgical resolution of CM I symptoms and symptoms related to TCS as well...
July 1, 2016: Turkish Neurosurgery
https://www.readbyqxmd.com/read/27593807/comparison-of-electrophysiological-outcomes-of-tethered-cord-syndrome-and-spinal-intradural-tumors-a-retrospective-clinical-study
#12
Serhat Pusat, Cahit Kural, Ilker Solmaz, Caglar Temiz, Yunus Kacar, Ozkan Tehli, Murat Kutlay, Mehmet Daneyemez, Yusuf Izci
AIM: Electrophysiological evaluation of the outcomes of spinal procedures is important for neurosurgeons. Somotosensorial evoqued potentials (SSEPs) are used for electrophysiological evaluation of tethered cord syndrome (TCS) and spinal intradural tumors (SIT). The aim of this study is to document the electrophysiological outcomes of surgery for TCS and SIT and to compare the results based on the preoperative diagnosis. MATERIAL AND METHODS: The data of 30 patients, who were operated for TCS and SIT between 2011 and 2013, were reviewed retrospectively...
February 5, 2016: Turkish Neurosurgery
https://www.readbyqxmd.com/read/27593774/management-of-tethered-cord-syndrome-in-adults-experience-of-23-cases
#13
Özden Erhan Sofuoğlu, Anas Abdallah, Erhan Emel, Ali Ender Ofluoğlu, Müslüm Güneş, Betül Güler
OBJECTIVE AND BACKGROUND: Tethered cord syndrome (TCS) in adults is rarely diagnosed as well as it is a complex clinicopathological entity that remains poorly understood. In this study, clinical outcomes of 23 consecutive congenital TCSs diagnosed in adults have been evaluated to establish a standard approach to treat congenital TCS diagnosed in adults. METHODS: Medical records were retrospectively reviewed in 73 cases of tethered cord syndrome whom underwent surgery in our hospital, between the years 2005 and 2014...
October 2, 2015: Turkish Neurosurgery
https://www.readbyqxmd.com/read/27559452/variation-in-outcome-in-tethered-cord-syndrome
#14
Noorulain Iqbal, Mohsin Qadeer, Salman Yousuf Sharif
STUDY DESIGN: Fifty patients surgically treated for tethered cord syndrome (TCS) were retrospectively studied at Liaquat National Hospital, Karachi from 2010 until 2014. PURPOSE: To assess the common presentations of TCS in our part of the world and the surgical outcome of the different presentations. OVERVIEW OF LITERATURE: TCS is a stretch-induced functional disorder of the spinal cord with its caudal part anchored by an inelastic structure, which results in characteristic symptoms and signs...
August 2016: Asian Spine Journal
https://www.readbyqxmd.com/read/27555994/comparative-study-of-untethering-and-spine-shortening-surgery-for-tethered-cord-syndrome-in-adults
#15
Hiroaki Nakashima, Shiro Imagama, Hiroki Matsui, Yasutsugu Yukawa, Koji Sato, Tokumi Kanemura, Mitsuhiro Kamiya, Kenyu Ito, Yukihiro Matsuyama, Naoki Ishiguro, Fumihiko Kato
STUDY DESIGN: Retrospective multicenter study. OBJECTIVE: Although untethering surgery has been a standard treatment in patients with adult tethered cord syndrome (TCS), spine-shortening osteotomy (SSO) has recently been performed as an alternative technique. The purpose of this study was to compare the clinical outcomes of the two procedures for TCS in adults. METHODS: Fourteen patients (37.7 ± 12.5 years) with TCS were enrolled at 6 hospitals...
September 2016: Global Spine Journal
https://www.readbyqxmd.com/read/27552167/a-new-finding-of-a-tethered-cord-in-a-patient-with-okamoto-syndrome
#16
Fatu S Conteh, Rachana Tyagi, Susan S Brooks
No abstract text is available yet for this article.
August 22, 2016: Clinical Dysmorphology
https://www.readbyqxmd.com/read/27497702/proposed-caudal-appendage-classification-system-spinal-cord-tethering-associated-with-sacrococcygeal-eversion
#17
C Corbett Wilkinson, Arianne J Boylan
INTRODUCTION: The most commonly used classification system for caudal appendages (aka human tails) dates from the 1980s and classifies appendages (tails) as either true tails or pseudotails. Advances in neuroimaging since the 1980s, however, as well as an ever-increasing number of reported cases, have made this system outdated. Sacrococcygeal eversion is a condition in which the distal sacral and coccygeal vertebrae are curved in a retroverted rather than anteverted direction. It can give rise to one type of caudal appendage...
August 6, 2016: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/27442670/complications-after-spinal-anesthesia-in-adult-tethered-cord-syndrome
#18
Jing-Jie Liu, Zheng Guan, Zhen Gao, Li Xiang, Feng Zhao, Sheng-Li Huang
Since little has been reported about complications of spinal anesthesia in adult tethered cord syndrome (TCS), we sought to delineate the characteristics of the condition.A total of 4 cases of adult TCS after spinal anesthesia were reviewed. The medical charts of the patients were obtained. Anesthesia, which was combined spinal and epidural anesthesia or spinal anesthesia was performed, and follow-up were carried out in all patients.The most common neurological symptom of adult TCS before surgery was occasional severe pain in back, perineal region, or legs...
July 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27430461/congenital-malformations-of-the-brain-and-spine
#19
Prashant Shankar, Carlos Zamora, Mauricio Castillo
In this chapter we briefly address the most common congenital brain and spinal anomalies as well as their most salient imaging, especially magnetic resonance, findings. Some of them, such as Chiari II, and open spinal defects, have become relatively rare due to their detection in utero and repair of the spinal malformation. Regardless of the type of brain anomaly, the most common clinical symptoms are mental retardation, hydrocephalus, and seizure; the latter two may need to be surgically and medically addressed...
2016: Handbook of Clinical Neurology
https://www.readbyqxmd.com/read/27430413/adult-cervicothoracic-lipomyelomeningocele
#20
Nancy Abu-Bonsrah, Taylor E Purvis, C Rory Goodwin, Rory J Petteys, Rafael De la Garza-Ramos, Daniel M Sciubba
Lipomyelomeningocele (LMM) as a cause of tethered cord syndrome (TCS) commonly presents in childhood in the lumbosacral spine. Patients frequently present with cutaneous manifestations, progressive neurological deterioration, bladder dysfunction, and intractable pain. Early surgical intervention with untethering is recommended for symptomatic patients. We report an unusual case of a woman who presented with a subcutaneous lump, pain, and neurological decline found to have a cervicothoracic LMM. The patient underwent laminectomy and subtotal resection of the mass; seventeen years later she was confined to a wheelchair with severe neurological decline ultimately requiring three additional attempts at surgical excision and repair...
October 2016: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
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