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C A Ibrahim-Verbaas, J Bressler, S Debette, M Schuur, A V Smith, J C Bis, G Davies, S Trompet, J A Smith, C Wolf, L B Chibnik, Y Liu, V Vitart, M Kirin, K Petrovic, O Polasek, L Zgaga, C Fawns-Ritchie, P Hoffmann, J Karjalainen, J Lahti, D J Llewellyn, C O Schmidt, K A Mather, V Chouraki, Q Sun, S M Resnick, L M Rose, C Oldmeadow, M Stewart, B H Smith, V Gudnason, Q Yang, S S Mirza, J W Jukema, P L deJager, T B Harris, D C Liewald, N Amin, L H Coker, O Stegle, O L Lopez, R Schmidt, A Teumer, I Ford, N Karbalai, J T Becker, M K Jonsdottir, R Au, R S N Fehrmann, S Herms, M Nalls, W Zhao, S T Turner, K Yaffe, K Lohman, J C van Swieten, S L R Kardia, D S Knopman, W M Meeks, G Heiss, E G Holliday, P W Schofield, T Tanaka, D J Stott, J Wang, P Ridker, A J Gow, A Pattie, J M Starr, L J Hocking, N J Armstrong, S McLachlan, J M Shulman, L C Pilling, G Eiriksdottir, R J Scott, N A Kochan, A Palotie, Y-C Hsieh, J G Eriksson, A Penman, R F Gottesman, B A Oostra, L Yu, A L DeStefano, A Beiser, M Garcia, J I Rotter, M M Nöthen, A Hofman, P E Slagboom, R G J Westendorp, B M Buckley, P A Wolf, A G Uitterlinden, B M Psaty, H J Grabe, S Bandinelli, D I Chasman, F Grodstein, K Räikkönen, J-C Lambert, D J Porteous, J F Price, P S Sachdev, L Ferrucci, J R Attia, I Rudan, C Hayward, A F Wright, J F Wilson, S Cichon, L Franke, H Schmidt, J Ding, A J M de Craen, M Fornage, D A Bennett, I J Deary, M A Ikram, L J Launer, A L Fitzpatrick, S Seshadri, C M van Duijn, T H Mosley
To identify common variants contributing to normal variation in two specific domains of cognitive functioning, we conducted a genome-wide association study (GWAS) of executive functioning and information processing speed in non-demented older adults from the CHARGE (Cohorts for Heart and Aging Research in Genomic Epidemiology) consortium. Neuropsychological testing was available for 5429-32,070 subjects of European ancestry aged 45 years or older, free of dementia and clinical stroke at the time of cognitive testing from 20 cohorts in the discovery phase...
February 2016: Molecular Psychiatry
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