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neonatal aortic thrombosis

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https://www.readbyqxmd.com/read/27599834/case-report-of-a-central-venous-access-device-associated-thrombosis-with-aortic-embolism-in-a-preterm-infant
#1
Marlene Biermayr, Barbara Brunner, Kathrin Maurer, Rudolf Trawoeger, Ursula Kiechl-Kohlendorfer, Vera Neubauer
BACKGROUND: Thrombosis in neonates is commonly a central venous access device (CVAD) associated complication. Furthermore, a patent foramen ovale (PFO) is frequently seen in preterm infants. Even though a coincidence of both is not unusual, detaching of the thrombus and organisation of an aortic embolism has not been described until now. Treatment recommendations of CVAD-associated thrombosis in neonates do not consider frequently seen complications of preterm infants e.g. intraventricular haemorrhage...
2016: BMC Pediatrics
https://www.readbyqxmd.com/read/27547054/intestinal-ischemia-in-neonates-and-children
#2
REVIEW
Ionuţ Isaia Jeican, Gabriela Ichim, Dan Gheban
The article reviews the intestinal ischemia theme on newborn and children. The intestinal ischemia may be either acute - intestinal infarction (by vascular obstruction or by reduced mesenteric blood flow besides the occlusive mechanism), either chronic. In neonates, acute intestinal ischemia may be caused by aortic thrombosis, volvulus or hypoplastic left heart syndrome. In children, acute intestinal ischemia may be caused by fibromuscular dysplasia, volvulus, abdominal compartment syndrome, Burkitt lymphoma, dermatomyositis (by vascular obstruction) or familial dysautonomia, Addison's disease, situs inversus abdominus (intraoperative), burns, chemotherapy administration (by nonocclusive mesenteric ischemia)...
2016: Clujul Medical (1957)
https://www.readbyqxmd.com/read/27133548/-cardiogenic-shock-due-to-spontaneous-neonatal-thrombosis-of-the-abdominal-aorta
#3
J Brice, P Venot, M Colinart-Thomas, P Morville
Neonatal arterial thrombosis is unusual and generally associated with an arterial umbilical catheter. Spontaneous aortic thrombosis is exceptional but its severity is related to high mortality rate and renovascular morbidity. We report here the observation of a 10-day-old term infant showing a large abdominal aortic thrombosis revealed by cardiogenic shock induced by systemic arterial hypertension. The resolution was fast following anticoagulant and antihypertensive therapy. Etiologic investigations showed renal failure and moderate hyperhomocysteinemia controlled by a vitamin supplement...
September 2016: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
https://www.readbyqxmd.com/read/26802308/abdominal-aortic-thrombosis-in-a-healthy-neonate
#4
Marko Bogović, Dino Papeš, Davorin Mitar, Ranko Smiljanić, Suzana Sršen-Medančić, Stanko Ćavar, Anko Antabak, Tomislav Luetić
Abdominal aortic thrombosis is a rare entity in neonates and has mostly been associated with umbilical artery or cardiac catheterization. We present a complicated case of an otherwise healthy neonate who developed thrombosis of abdominal aorta with renal failure. Therapy with intravenous heparin was unsuccessful, and thrombolysis was contraindicated because of disseminated intravascular coagulation so we decided to perform open thrombectomy using the left retroperitoneal approach. The following day, thrombosis recurred in the same extent and despite high risk of bleeding Alteplase was eventually given, which resulted in recanalization of the aorta 6 hours later...
April 2016: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/26265897/a-case-of-neonatal-arterial-thrombosis-mimicking-interrupted-aortic-arch
#5
Hazım Alper Gürsu, Birgül Varan, Ayla Oktay, Murat Özkan
Neonatal arterial thrombosis is a very rare entity with clinical findings resembling coarctation of aorta or interrupted aortic arch. A two day-old male newborn was admitted to a different hospital with difficulty in sucking and sleepiness. On echocardiographic examination, a diagnosis of interrupted aortic arch was made and he was treated with prostoglandin E2. When the patient presented to our center, physical examination revealed that his feet were bilaterally cold. The pulses were not palpable and there were ecchymotic regions in the lower extremities...
June 2015: Türk Pediatri Arşivi
https://www.readbyqxmd.com/read/26204695/feto-maternal-outcomes-of-urgent-open-heart-surgery-during-pregnancy
#6
Saeid Hosseini, Fahimeh Kashfi, Niloufar Samiei, Amirjamshid Khamoushi, Alireza Alizadeh Ghavidel, Forouzan Yazdanian, Yalda Mirmesdagh, Carlos A Mestres
BACKGROUND AND AIM OF THE STUDY: Cardiac surgery during pregnancy is rarely required and potentially increases feto-maternal mortality. The study aim was to evaluate pregnancy outcomes in females who underwent open-heart surgery with cardiopulmonary bypass (CPB) during pregnancy. METHODS: Between 1999 and 2014, a total of 16 pregnant women (mean age 27 ± 7 years; mean gestational age 13 ± 7.7 weeks) underwent urgent cardiac surgery using CPB. The preoperative diagnosis included prosthetic valve dysfunction in 12 women (five aortic, seven mitral), native valve endocarditis and critical aortic stenosis each in one woman, and intracardiac masses in two women...
March 2015: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/26159560/hemodynamics-in-a-pediatric-ascending-aorta-using-a-viscoelastic-pediatric-blood-model
#7
Bryan C Good, Steven Deutsch, Keefe B Manning
Congenital heart disease is the leading cause of infant death in the United States with over 36,000 newborns affected each year. Despite this growing problem there are few mechanical circulatory support devices designed specifically for pediatric and neonate patients. Previous research has been done investigating pediatric ventricular assist devices (PVADs) assuming blood to be a Newtonian fluid in computational fluid dynamics (CFD) simulations, ignoring its viscoelastic and shear-thinning properties. In contrast to adult VADs, PVADs may be more susceptible to hemolysis and thrombosis due to altered flow into the aorta, and therefore, a more accurate blood model should be used...
April 2016: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/25639418/neoaortic-thrombus-after-norwood-procedure-complication-of-extracorporeal-life-support
#8
Andrew L Mesher, Joshua L Hermsen, Agustin E Rubio, Jonathan M Chen, David Michael McMullan
Hypoplastic left heart syndrome is the most common diagnosis among infants requiring cardiac extracorporeal life support (ECLS) in the neonatal period, with more than half of patients experiencing an ECLS-related complication. We present a case of nearly obstructing neoaortic thrombus during ECLS occurring in the early postoperative period after modified Norwood palliation of hypoplastic left heart syndrome. Stasis within the neoaortic root due to the increased ventricular afterload associated with venoarterial ECLS may have potentiated this complication...
February 2015: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/25404555/computational-fluid-dynamics-characterization-of-blood-flow-in-central-aorta-to-pulmonary-artery-connections-importance-of-shunt-angulation-as-a-determinant-of-shear-stress-induced-thrombosis
#9
Carey Celestin, Martin Guillot, Nancy Ross-Ascuitto, Robert Ascuitto
The central aortic shunt, consisting of a Gore-Tex (polytetrafluoroethylene) tube (graft) connecting the ascending aorta to the pulmonary artery, is a palliative operation for neonates with cyanotic congenital heart disease. These tubes often have an extended length, and therefore must be angulated to complete the connection to the posterior pulmonary arteries. Thrombosis of the graft is not uncommon and can be life-threatening. We have shown that a viscous fluid (such as blood) traversing a curve or bend in a small-caliber vessel or conduit can give rise to marked increases in wall shear stress, which is the major mechanical factor responsible for vascular thrombosis...
March 2015: Pediatric Cardiology
https://www.readbyqxmd.com/read/25362925/-aortic-thrombosis-in-a-newborn
#10
Patricia Valero Menchén, Daniel Blázquez Gamero
The aortic thrombosis is not frequent during the neonatal period. The canalization of umbilical artery is the main risk factor. There are several options for the treatment, such as thrombolysis, thrombectomy and the anticoagulation, which are used in terms of the thrombosis localization and the symptoms that are observed. We present the case of a newborn who consulted for weak femoral pulses, coldness and poor perfusion of lower limbs. The aorta restriction was ruled out using the echocardiography; Doppler abdominal ecography showed aortic thrombosis at an underrenal level...
December 2014: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/25080835/unusual-intraatrial-thrombus-in-a-neonate-with-coarctation-of-the-aorta
#11
D Abid, S Ben Ameur, M Ly, E Daoud, S Mrabet, M Hachicha, Z Mnif, S Kammoun
Left atrial thrombus in neonates is uncommon. We describe a newborn with coarctation of the aorta, in whom a thrombus confined to the left appendage was discovered on the first day of life and was thought to be a myxoma.
September 2014: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
https://www.readbyqxmd.com/read/24573210/spontaneous-thrombosis-of-the-abdominal-aorta-in-two-neonates
#12
F Piersigilli, C Auriti, F Landolfo, F Campi, P Schingo, A Dotta
Although relatively rare, thromboembolic events are a major complication of invasive procedures, mainly vascular catheterization, required for the survival of neonates admitted to the neonatal intensive care unit. Sometimes symptoms may be ambiguous and the diagnosis may not be immediate. The clinical relevance of polymorphism of methilene tetrahydrofolate reductase (MTHFR) gene heterozigosity and of omocystein level in the genesis of these thromboembolic events are poorly understood. We report two cases of thrombosis of the abdominal aorta, mimicking aortic coarctation, in two neonates, successfully treated at diagnosis with 170 UI/Kg of low molecular weight heparin (LMWH) twice daily, without side effects...
March 2014: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/24490470/-hypertensive-crisis-in-children-and-adolescents
#13
REVIEW
Piotr Skrzypczyk, Maria Roszkowska-Blaim, Maria Daniel
Hypertensive crisis is a sudden rise in blood pressure above 99 c. for sex, age and height +5 mm Hg. Depending on patient's symptoms, hypertensive crisis can be divided into hypertensive emergency severe arterial hypertension with target organ insufficiency and/r damage (central nervous system, heart, kidney, eye), and hypertensive urgency - severe arterial hypertension without target organ insufficiency and damage with non-specific symptoms like: headaches, vertigo, nasal bleeding, nausea, and vomiting. The most common causes of hypertensive crisis in neonates and infants are renal artery thrombosis, broncho-pulmonary dysplasia, and coarctation of aorta; in older children - kidney diseases and renal artery stenosis...
December 2013: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/24382903/neonatal-aortic-thrombosis-as-a-result-of-congenital-homocystinuria
#14
Bonny Jasani, Ruchi Nanavati
BACKGROUND: Arterial thrombosis, that too in aorta is rare in neonates. CASE CHARACTERISTICS: A 4-day-old presented with non-recordable BP in lower limbs. Doppler ultrasonography of abdomen revealed aortic thrombus. OBSERVATION: Serum homocysteine level was elevated (25.5 umol/L). OUTCOME: Thrombus resolved with subcutaneous LMW heparin therapy for 2 weeks. MESSAGE: Congenital classic homocystinuria can rarely cause aortic thrombosis in neonatal period...
November 8, 2013: Indian Pediatrics
https://www.readbyqxmd.com/read/23820172/spontaneous-aortic-arch-thrombosis-in-a-neonate
#15
Sarah Sainte, Bert Suys, Bart Meyns, Filip Rega
No abstract text is available yet for this article.
September 2013: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/23480928/acute-aortoiliac-thrombotic-occlusion-in-an-infant-with-protein-c-deficiency-and-small-atrial-sepal-defect-a-rare-case
#16
Raj K Yadav, Vimal Kant Yadav, Pradeep Pokharna, Rajendra M Mathur
Aortoiliac thrombosis is rare in infants and neonates. Protein C deficiency is frequently observed with venous thromboembolism, but off-late report of arterial thrombosis is increasingly common. We report a case of large infrarenal aortoiliac saddle and right popliteal artery thrombosis in a 7-month-old infant, with 3-mm atrial septal defect without clinical and Doppler evidence of deep vein thrombosis, presented with acute bilateral lower limb ischemic attack. Diagnosis was made by computed tomographic (C T) angiography of aorta and bilateral lower limbs...
March 2013: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/23336428/neonatal-aortic-arch-thrombosis-analysis-of-thrombophilic-risk-factors-and-prognosis
#17
REVIEW
Ivonne Wieland, Thomas Jack, Kathrin Seidemann, Martin Boehne, Florian Schmidt, Christoph M Happel, Harald Koeditz, Harald Bertram, Michael Sasse
UNLABELLED: Arterial thrombosis in neonates and children is a rare event and is often associated with external risk factors such as asphyxia or sepsis. We report our experiences with two neonates with spontaneous aortic arch thrombosis mimicking aortic coarctation. Despite single case reports until now, no data exist for the underlying thrombophilic risk factors and prognosis of this rare event. Both patients were carriers of a heterozygous factor V Leiden mutation, which has been reported once before as a risk factor for aortic arch thrombosis...
February 2014: Cardiology in the Young
https://www.readbyqxmd.com/read/23031352/neonatal-ascending-aortic-thrombus-successful-medical-treatment
#18
Roberto Gallotti, Cheryl E Cammock, Natalia Dixon, Yoshio Ootaki
Neonatal aortic thrombosis is a potentially life-threatening condition with significant morbidity and mortality if undiagnosed and untreated. The most common location of arterial thrombosis in neonates is in the abdominal aorta and is associated with umbilical artery catheterisation. There are only a few previous reports of thrombosis in the ascending aorta. We describe a case of ascending aortic thrombosis in a neonate who underwent successful thrombolytic therapy.
August 2013: Cardiology in the Young
https://www.readbyqxmd.com/read/22665862/severe-hypernatremic-dehydration-associated-with-cerebral-venous-and-aortic-thrombosis-in-the-neonatal-period
#19
Mohammed Hbibi, Sana Abourazzak, Abdeladim Babakhouya, Meryem Boubou, Samir Atmani, Siham Tizniti, Abdelhak Bouharrou
Severe neonatal hypernatremia is an important electrolyte disorder that has serious effects. Cerebral venous thrombosis and aortic thrombosis are relatively rare in severe neonatal hypernatremic dehydration. The authors report a case of cerebral venous thrombosis, associated with aortic thrombosis revealed by dehydration in a 9-day-old boy. Diagnostic was performed using Doppler ultrasound and imaging techniques. Thrombosis was resolved after anticoagulation treatment with low-molecular weight heparin for 1 month, and then was substituted by oral anticoagulant...
2012: BMJ Case Reports
https://www.readbyqxmd.com/read/22461322/descending-aorta-thrombus-in-a-neonate-mimicking-coarctation-of-the-aorta-mechanical-thrombectomy-using-the-angiojet-%C3%A2-catheter
#20
Jennifer F Gerardin, Cindy S Anderson, Aimee K Armstrong, Ronald G Grifka
A 5-day-old neonate presented in shock, with signs and symptoms of severe coarctation of the aorta. He was diagnosed with a patent aortic arch, and a completely thrombosed abdominal aorta. The authors report the successful transcatheter removal of the entire thrombus using the AngioJet(®) Thrombectomy system. This represents the first published use of the AngioJet(®) catheter in the aorta of a pediatric patient.
February 2013: Catheterization and Cardiovascular Interventions
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