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https://www.readbyqxmd.com/read/28532010/design-of-experiments-for-microencapsulation-applications-a-review
#1
REVIEW
Filipa Paulo, Lúcia Santos
Microencapsulation techniques have been intensively explored by many research sectors such as pharmaceutical and food industries. Microencapsulation allows to protect the active ingredient from the external environment, mask undesired flavours, a possible controlled release of compounds among others. The purpose of this review is to provide a background of design of experiments in microencapsulation research context. Optimization processes are required for an accurate research in these fields and therefore, the right implementation of micro-sized techniques at industrial scale...
August 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28531863/biodiesel-production-from-spirulina-microalgae-feedstock-using-direct-transesterification-near-supercritical-methanol-condition
#2
Hamed Mohamadzadeh Shirazi, Javad Karimi-Sabet, Cyrus Ghotbi
Microalgae as a candidate for production of biodiesel, possesses a hard cell wall that prevents intracellular lipids leaving out from the cells. Direct or in situ supercritical transesterification has the potential for destruction of microalgae hard cell wall and conversion of extracted lipids to biodiesel that consequently reduces the total energy consumption. Response surface methodology combined with central composite design was applied to investigate process parameters including: Temperature, Time, Methanol-to-dry algae, Hexane-to-dry algae, and Moisture content...
April 21, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28531351/pharmaceutical-intermediate-modified-gold-nanoparticles-against-multidrug-resistant-bacteria-and-wound-healing-application-via-electrospun-scaffold
#3
Xinglong Yang, Junchuan Yang, Le Wang, Bei Ran, Yuexiao Jia, Lingmin Zhang, Guang Yang, Huawu Shao, Xingyu Jiang
Remedying multidrug-resistant (MDR) bacteria wound infection is major challenge due to the inability of conventional antibiotics in treating such infections against MDR bacteria. Thus, developing wound dressings for wound care, particularly against MDR bacteria, is in huge demand. Here, we present a strategy in designing wound dressings: we use a small molecule (6-aminopenicillanic acid, APA)-coated gold nanoparticles (AuNPs) to inhibit MDR bacteria. We dope the AuNPs into electrospun fibers of poly(ε-caprolactone) (PCL)/gelatin to yield materials that guard against wound infection by MDR bacteria...
May 22, 2017: ACS Nano
https://www.readbyqxmd.com/read/28531299/pain-energy-model-of-mobility-limitation-in-the-older-adult
#4
Peter C Coyle, Jennifer A Schrack, Gregory E Hicks
Background. : Chronic pain is prevalent, costly, and disabling among older adults. Although mobility decline is inevitable with aging, it is clear, from current evidence, that older adults with chronic pain experience a greater rate of functional mobility decline than their pain-free peers. Past studies suggest that pain expedites the age-related decline in functional mobility; however, the pathways through which pain affects mobility remain unclear. Gerontological experts hypothesize that the age-related decline in mobility may be driven by alterations in energy expenditure; these concepts are outlined in a model known as the Energetic Pathway of Mobility Loss...
May 22, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/28530619/-current-status-of-laparoscopic-sacrocolpopexy-in-the-treatment-of-pelvic-organ-prolapse
#5
Carmen González-Enguita, Natalia Gennaro-DellaRossa, Esther López-López, Juliana Escobar-Castaño, Percy Miguel Rodríguez-Castro, Raquel González-López
OBJECTIVES: Surgical restoration of pelvic floor anatomy in pelvic organ prolapse (POP) should avoid extensive areas that may injure healthy tissues and lead to scar fibrosis producing dysfunctional rigidity. Laparoscopic sacrocolpopexy corrects POP by lifting pelvic elements with a minimally invasive procedure.Various current strategies and approaches make it a diverse procedure. METHODS: We performed a bibliographic review on the published experience about abdominal sacrocolpopexy over the last 20 years...
May 2017: Archivos Españoles de Urología
https://www.readbyqxmd.com/read/28530520/cardiovascular-disease-and-gout-real-world-experience-evaluating-patient-characteristics-treatment-patterns-and-health-care-utilization
#6
Michael H Pillinger, Sripal Bangalore, Alyssa B Klein, Scott Baumgartner, Robert Morlock
BACKGROUND: Gout, hyperuricemia, and cardiovascular disease (CVD) are prevalent conditions in the United States, and while they share common risk factors such as obesity, hypertension, hypercholesterolemia, and type 2 diabetes mellitus, relatively little is known about what patient and disease characteristics may link CVD with hyperuricemia and gout and how the presence of both diseases affects management decisions differently than for patients with gout alone. OBJECTIVE: To identify differences in patient characteristics, patterns of urate-lowering therapy (ULT) use, and gout control in gout patients with and without cardiovascular comorbidity...
June 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28530424/the-collection-of-historical-instruments-at-national-taiwan-university
#7
Lothar Spillmann, Su-Ling Yeh, Chien-Chung Chen, Keng-Cheng Liang, Shojiro Sakurai
This article presents three of the historical instruments from the National Taiwan University collection. The instruments were built between 1894 and 1902. The instruments are (1) Meumann's Largest Time Sense Apparatus, (2) Wundt's Pendulum Tachistoscope, and (3) Schumann's Wheel Tachistoscope. It is hoped that the presentation of these three historical instruments will serve a triple purpose: (a) to enable a greater appreciation of achievements of the scientists on whose shoulders we stand; (b) to illustrate the need for the time-consuming task of designing specialized apparatuses for a given experiment, typical at the time; and (c) to encourage a reflection on the mutual relationship between the instruments available, the questions asked, and the experiments done...
May 2017: History of Psychology
https://www.readbyqxmd.com/read/28530209/reproducible-3d-printed-head-tanks-for-electrical-impedance-tomography-with-realistic-shape-and-conductivity-distribution
#8
James Avery, Kirill Aristovich, Barney Low, David Holder
OBJECTIVE: Electrical impedance tomography (EIT) has many promising applications in brain injury monitoring. To evaluate both instrumentation and reconstruction algorithms, experiments are first performed in head tanks. Existing methods, whilst accurate, produce a discontinuous conductivity, and are often made by hand, making it hard for other researchers to replicate. APPROACH: We have developed a method for constructing head tanks directly in a 3D printer. Conductivity was controlled through perforations in the skull surface, which allow for saline to pass through...
May 22, 2017: Physiological Measurement
https://www.readbyqxmd.com/read/28530187/application-of-snps-to-improve-yield-of-pisum-sativum-l-pea
#9
Ansar Mehmood, Ghulam Murtaza
Nanotechnology opens an enormous scope of novel application in the fields of biotechnology and agricultural industries, because nanoparticles (NPs) have unique physicochemical properties, i.e. high surface area, high reactivity, tunable pore size and particle morphology. Present study was carried out to determine the role of silver NPs (SNPs) to improve yield of Pisum sativum L. SNPs (10-100 nm) were synthesised by green method using extract of Berberis lycium Royle. Pea seeds were soaked and seedling were foliage sprayed by 0, 30, 60 and 90 ppm SNPs...
June 2017: IET Nanobiotechnology
https://www.readbyqxmd.com/read/28529710/introducing-the-brassica-information-portal-towards-integrating-genotypic-and-phenotypic-brassica-crop-data
#10
Annemarie H Eckes, Tomasz Gubała, Piotr Nowakowski, Tomasz Szymczyszyn, Rachel Wells, Judith A Irwin, Carlos Horro, John M Hancock, Graham King, Sarah C Dyer, Wiktor Jurkowski
The Brassica Information Portal (BIP) is a centralised repository for Brassica phenotypic data. Trait data associated with Brassica research and breeding experiments conducted on Brassica crops, used as vegetables, for livestock fodder and biofuels, is hosted on the site, together with information on the experimental plant materials used, as well as trial design. BIP is an open access and open source project, built on the schema of CropStoreDB, and as such can provide trait data management strategies for any crop data...
2017: F1000Research
https://www.readbyqxmd.com/read/28529464/trap-design-and-construction-for-high-power-multinuclear-magnetic-resonance-experiments
#11
Joseph V Rispoli, Ivan E Dimitrov, Sergey Cheshkov, Craig Malloy, Steven M Wright, Mary P McDougall
Performing multinuclear experiments requires one or more radiofrequency (RF) coils operating at both the proton and second-nucleus frequencies; however, inductive coupling between coils must be mitigated to retain proton sensitivity and coil tuning stability. The inclusion of trap circuits simplifies placement of multinuclear RF coils while maintaining inter-element isolation. Of the commonly investigated non-proton nuclei, perhaps the most technically demanding is carbon-13, particularly when applying a proton decoupling scheme to improve the resulting spectra...
October 2016: Concepts in Magnetic Resonance. Part B, Magnetic Resonance Engineering
https://www.readbyqxmd.com/read/28529122/shared-decision-making-a-buzz-word-in-the-netherlands-the-pace-quickens-towards-nationwide-implementation%C3%A2
#12
Trudy van der Weijden, Heleen Post, Paul L P Brand, Haske van Veenendaal, Ton Drenthen, Linda Aj van Mierlo, Peep Stalmeier, Olga C Damman, Anne Stiggelbout
Currently, shared decision making (SDM) is on the agenda among target patient representative groups, policy makers and professional bodies. Although the International Conference for Shared Decision Making (ISDM) 2011 generated a positive boost, hesitation was also felt among Dutch clinicians, who are challenged by many new tasks. No hesitation is seen among the majority of patients, opting mostly for the SDM model. We haven't reached these patients' needs fully yet, given disappointing research data on patients' experiences and professional behaviour...
May 18, 2017: Zeitschrift Für Evidenz, Fortbildung und Qualität Im Gesundheitswesen
https://www.readbyqxmd.com/read/28529067/immunoproapoptotic-molecule-scfv-fdt-tbid-modified-mesenchymal-stem-cells-for-prostate-cancer-dual-targeted-therapy
#13
Fengqi Yan, Xia Li, Nan Li, Rui Zhang, Qinhao Wang, Yi Ru, Xiaoke Hao, Jianxin Ni, He Wang, Guojun Wu
Highly efficient target therapy is urgently needed for prostate cancer with overexpression of γ-seminoprotein (γ-SM). Recent studies indicated that mesenchymal stem cells (MSCs) are attractive candidate for cell-based, targeted therapy due to their tumor tropism. Here we designed a dual-target therapeutic system in which MSCs were engineered to produce and deliver scFv-Fdt-tBid, a novel γ-SM-targeted immunoproapoptotic molecule. Such engineered MSCs (MSC.scFv-Fdt-tBid) would home to tumor sites and release the fusion protein to induce the apoptosis of prostate cancer cells...
May 18, 2017: Cancer Letters
https://www.readbyqxmd.com/read/28529027/management-of-postneurosurgical-meningitis-narrative-review
#14
REVIEW
Khetam Hussein, Roni Bitterman, Ben Shofty, Mical Paul, Ami Neuberger
BACKGROUND: Infections complicating neurosurgery pose unacceptable mortality and morbidity. AIMS: To summarize what is known about the epidemiology, diagnosis and treatment of post-neurosurgical meningitis (PNM). SOURCES: PubMed, references of identified studies and reviews, and personal experience when evidence was lacking. CONTENT: The incidence and pathogen distribution of PNM is highly variable. A shift towards Gram-negative bacteria has been observed with use of antibiotic prophylaxis and antibiotic-coated devices directed mainly against Gram-positive bacteria...
May 18, 2017: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/28528893/body-temperature-responses-to-handling-stress-in-wintering-black-capped-chickadees-poecile-atricapillus-l
#15
Agnès Lewden, Andreas Nord, Magali Petit, François Vézina
Body temperature variation in response to acute stress is typically characterized by peripheral vasoconstriction and a concomitant increase in core body temperature (stress-induced hyperthermia). It is poorly understood how this response differs between species and within individuals of the same species, and how it is affected by the environment. We therefore investigated stress-induced body temperature changes in a non-model species, the Black-capped Chickadee, in two environmental conditions: outdoors in low ambient temperature (mean: -6...
May 18, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/28528784/keeping-the-voice-fit-in-the-group-fitness-industry-a-qualitative-study-to-determine-what-instructors-want-in-a-voice-education-program
#16
Patrick J Aiken, Anna F Rumbach
OBJECTIVES: This study aimed to provide a descriptive summary of (1) group fitness instructors' (GFIs') experiences of occupational voice use and education, and (2) the content and mode of delivery desired by GFIs in an education and training program. STUDY DESIGN: This is a qualitative inductive approach using a semi-structured interview. METHOD: Semi-structured interviews were conducted with eight GFIs recruited via self-selection sampling...
May 18, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/28528592/client-perceptions-of-helpfulness-in-therapy-a-novel-video-rating-methodology-for-examining-process-variables-at-brief-intervals-during-a-single-session
#17
Alexandra A Cocklin, Warren Mansell, Richard Emsley, Phil McEvoy, Chloe Preston, Jody Comiskey, Sara Tai
BACKGROUND: The value of clients' reports of their experiences in therapy is widely recognized, yet quantitative methodology has rarely been used to measure clients' self-reported perceptions of what is helpful over a single session. AIMS: A video-rating method using was developed to gather data at brief intervals using process measures of client perceived experience and standardized measures of working alliance (Session Rating Scale; SRS). Data were collected over the course of a single video-recorded session of cognitive therapy (Method of Levels Therapy; Carey, 2006; Mansell et al...
May 22, 2017: Behavioural and Cognitive Psychotherapy
https://www.readbyqxmd.com/read/28528560/design-and-implementation-of-a-community-health-worker-hiv-treatment-and-prevention-intervention-in-an-hiv-hot-spot-fishing-community-in-rakai-uganda
#18
Amanda Long, Ismail Mbabali, Heidi E Hutton, Alvin G Thomas, Eva Bugos, Jeremiah Mulamba, Kathy Rivet Amico, Fred Nalugoda, Ronald H Gray, Maria J Wawer, Gertrude Nakigozi, Larry W Chang
Innovative approaches are needed to increase engagement in HIV treatment and prevention services, particularly in HIV hot spots. Here, we detail our design, training approach, and early implementation experiences of a community-based HIV intervention called "health scouts." The intervention, utilizing a novel, theory-based approach, trained 10 community residents in an HIV hot spot fishing community to use motivational interviewing strategies and a mobile phone-based counseling application. During the first 3 months, 771 residents (median 82/health scout, range 27-160) were counseled...
January 1, 2017: Journal of the International Association of Providers of AIDS Care
https://www.readbyqxmd.com/read/28528530/evaluation-of-ratite-skinning-force-in-order-to-fix-plant-and-mechanical-solutions
#19
Biagio Bianchi
The skin is the most requested product of ratite slaughter and 'first-rate' ratite's skin has a high economic market. Ostrich hide is tanned in South Africa and sold all over the world. Besides, the ostrich meat is considered a niche production in the marketplace, thus allowing for another pro t for the ostrich breeding. Theorical analysis of skinning process has been carried out, and an automatic measurement system has been designed to record the drawing-force on the animal's body during skinning tests. The aim of this study was to indentify the best animal position and provide values of drawing-force in order to design a speci c machine for ostrich skinning...
May 12, 2017: Veterinaria Italiana
https://www.readbyqxmd.com/read/28528394/a-novel-dual-wavelength-laser-stimulator-to-elicit-transient-and-tonic-nociceptive-stimulation
#20
Xiaoxi Dong, Tianjun Liu, Han Wang, Jichun Yang, Zhuying Chen, Yong Hu, Yingxin Li
This study aimed to develop a new laser stimulator to elicit both transient and sustained heat stimulation with a dual-wavelength laser system as a tool for the investigation of both transient and tonic experimental models of pain. The laser stimulator used a 980-nm pulsed laser to generate transient heat stimulation and a 1940-nm continuous-wave (CW) laser to provide sustained heat stimulation. The laser with 980-nm wavelength can elicit transient pain with less thermal injury, while the 1940-nm CW laser can effectively stimulate both superficial and deep nociceptors to elicit tonic pain...
May 20, 2017: Lasers in Medical Science
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