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https://www.readbyqxmd.com/read/29793207/infectivity-reduction-efficacy-of-uv-irradiation-and-peracetic-acid-uv-combined-treatment-on-ms2-bacteriophage-and-murine-norovirus-in-secondary-wastewater-effluent
#1
ShihChi Weng, Nathan Dunkin, Kellogg J Schwab, James McQuarrie, Kati Bell, Joseph G Jacangelo
Peracetic acid (PAA) is a strong oxidant/bactericide that has been applied in various industries (e.g., food processing, pharmaceuticals, medical device sterilization, etc.) as a disinfectant. There is increasing interest in using PAA for wastewater disinfection because it does not form halogenated byproducts, and no post-treatment quenching is required. Previous studies have demonstrated good efficiency in controlling bacteria in wastewater, but limited information is available for viruses, especially those hosted by mammals (e...
May 21, 2018: Journal of Environmental Management
https://www.readbyqxmd.com/read/29793198/assessment-of-cu-sub-lethal-toxicity-lc-50-in-the-cold-water-gorgonian-dentomuricea-meteor-under-a-deep-sea-mining-activity-scenario
#2
Inês Martins, António Godinho, Joana Goulart, Marina Carreiro-Silva
Previous aquaria-based experiments have shown dissolution and leaching of metals, especially copper (Cu), from the simulated sediment plumes generated during mining activities resulting in a pronounced increase of Cu contamination in the surrounding seawater. Metals are bioavailable to corals with food, through ingestion (particulate phase) and through tissue-facilitated transport (passive diffusion). With corals being particularly vulnerable to metal contamination, resuspension of metal-bearing sediments during mining activities represents an important ecological threat...
May 21, 2018: Environmental Pollution
https://www.readbyqxmd.com/read/29793155/lessons-from-mosquitoes-painless-piercing
#3
Dev Gurera, Bharat Bhushan, Navin Kumar
Arthropods are the largest group of the living organisms. They attack other organisms by biting, stinging, or piercing and sucking. Among various medically important arthropods, which feed on living hosts, mosquitoes' piercing spread viruses which have been reported to cause the highest number of deaths annually. The primary cause of the deaths is malaria, which is spread by infected mosquitoes' piercing. This study aims at elucidating lessons from mosquitoes' painless piercing. Mosquitoes pierce using their fascicle, which is a bundle of coherently functioning six stylets...
May 18, 2018: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29793112/3d-printed-membrane-as-an-alternative-to-amniotic-membrane-for-ocular-surface-conjunctival-defect-reconstruction-an-in-vitro-in-vivo-study
#4
Shima Dehghani, Morteza Rasoulianboroujeni, Hamed Ghasemi, Saeed Heidari Keshel, Zohreh Nozarian, Mohammad Naser Hashemian, Mehran Zarei-Ghanavati, Golshan Latifi, Reza Ghaffari, Zhanfeng Cui, Hua Ye, Lobat Tayebi
BACKGROUND: The aim of this study was to evaluate the surgical handling and clinical applicability of a specific 3D-printed membrane design fabricated using a gelatin, elastin and sodium hyaluronate blend for conjunctival reconstruction and compare it with amniotic membrane (AM), which is normally used in such surgeries. METHODS: 3D printing technique was employed to fabricate the membrane based on gradient design. Prior to printing, rheometry was employed to optimize the ink composition...
May 11, 2018: Biomaterials
https://www.readbyqxmd.com/read/29793083/optimization-adsorption-of-norfloxacin-onto-polydopamine-microspheres-from-aqueous-solution-kinetic-equilibrium-and-adsorption-mechanism-studies
#5
Yibei Wan, Xiao Liu, Penglei Liu, Lei Zhao, Weihua Zou
Polydopamine microspheres (PDMPs) synthesized by a facile solution oxidation method were adopted as a potential adsorbent for the removal of Norfloxacin (NOR) from aqueous solution. The morphologies and properties of PDMPs were characterized using TEM, SEM, FTIR and pHPZC . Parameters effects such as contact time, initial pH, initial concentration and ionic strength on the adsorption capacity of NOR onto PDMPs were studied. To maximize NOR removal from liquid phase, Box-Behnken experimental design (BBD) combined with response surface modeling (RSM) was employed based on the 17 preliminary experiments at 308 K...
May 21, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29793061/microstructural-imaging-of-the-human-brain-with-a-super-scanner-10-key-advantages-of-ultra-strong-gradients-for-diffusion-mri
#6
D K Jones, D C Alexander, R Bowtell, M Cercignani, F Dell'Acqua, D J McHugh, K L Miller, M Palombo, G J M Parker, U S Rudrapatna, C M W Tax
The key component of a microstructural diffusion MRI 'super-scanner' is a dedicated high-strength gradient system that enables stronger diffusion weightings per unit time compared to conventional gradient designs. This can, in turn, drastically shorten the time needed for diffusion encoding, increase the signal-to-noise ratio, and facilitate measurements at shorter diffusion times. This review, written from the perspective of the National Facility for In Vivo MR Imaging of Human Tissue Microstructure, an initiative to establish a shared 300 mT/m-gradient facility amongst the microstructural imaging community, describes ten advantages of ultra-strong gradients for microstructural imaging...
May 21, 2018: NeuroImage
https://www.readbyqxmd.com/read/29792992/frailty-status-as-a-predictor-of-three-month-cognitive-and-functional-recovery-following-spinal-surgery-a-prospective-pilot-study
#7
Robert J Rothrock, Jeremy M Steinberger, Henry Badgery, Andrew C Hecht, Samuel K Cho, John M Caridi, Stacie Deiner
Background Context As increasing numbers of elderly Americans undergo spinal surgery, it is important to identify which patients are at highest risk for poor cognitive and functional recovery. Frailty is a geriatric syndrome which has been closely linked to poor outcomes, and short form screening may be a helpful tool for preoperative identification of at risk patients. Purpose To conduct a pilot study on the usefulness of a short-form screening tool to identify elderly patients at increased risk for prolonged cognitive and functional recovery following elective spine surgery...
May 21, 2018: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29792940/a-randomized-control-trial-to-determine-the-effectiveness-and-physiological-effects-of-spinal-manipulation-and-spinal-mobilization-compared-to-each-other-and-a-sham-condition-in-patients-with-chronic-low-back-pain-study-protocol-for-the-relief-study
#8
Brian C Clark, David W Russ, Masato Nakazawa, Christopher R France, Stevan Walkowski, Timothy D Law, Megan Applegate, Niladri Mahato, Samuel Lietkam, James Odenthal, Daniel Corcos, Simeon Hain, Betty Sindelar, Robert J Ploutz-Snyder, James S Thomas
BACKGROUND: Low back pain (LBP) is one of the most common reasons for seeking medical care. Manipulative therapies are a common treatment for LBP. Few studies have compared the effectiveness of different types of manipulative therapies. Moreover, the physiologic mechanisms underlying these treatments are not fully understood. Herein, we present the study protocol for The Researching the Effectiveness of Lumbar Interventions for Enhancing Function Study (The RELIEF Study). METHODS AND STUDY DESIGN: The RELIEF Study is a Phase II RCT with a nested mechanistic design...
May 21, 2018: Contemporary Clinical Trials
https://www.readbyqxmd.com/read/29792710/measuring-the-adhesion-forces-for-the-multivalent-binding-of-vancomycin-conjugated-dendrimer-to-bacterial-cell-wall-peptide
#9
Elizabeth Peterson, Christine Joseph, Hannah Peterson, Rachael Bouwman, Shengzhuang Tang, Jayme Cannon, Kumar Sinniah, Seok Ki Choi
Multivalent ligand-receptor interaction provides the fundamental basis for the hypothetical notion that high binding avidity relates to the strong force of adhesion. Despite its increasing importance in the design of targeted nanoconjugates, an understanding of the physical forces underlying the multivalent interaction remains a subject of urgent investigation. In this study, we designed three vancomycin (Van)-conjugated dendrimers G5(Van)n (n = mean valency = 0, 1, 4) for bacterial targeting with generation 5 (G5) poly(amidoamine) dendrimer as a multivalent scaffold, and evaluated both their binding avidity and physical force of adhesion to a bacterial model surface by employing surface plasmon resonance (SPR) spectroscopy and atomic force microscopy (AFM)...
May 24, 2018: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/29792568/physical-ergonomics-awareness-in-an-offshore-processing-platform-among-malaysian-oil-and-gas-workers
#10
M Hafizul Hilmi, Raja Ariffin Raja Ghazilla
INTRODUCTION: The reliability of offshore oil and gas (O&G) facilities depend on the operation and maintenance activities, where human physical intervention is involved. Workers are often exposed to ergonomics hazards due to inefficient workplace design. Ergonomics awareness among workers is a crucial factor in mitigating such hazards. OBJECTIVES: This study intends to evaluate the state of physical ergonomics awareness among Malaysian O&G workers and to assess their perception towards the criticality of physical ergonomics issues within an offshore processing facility...
May 24, 2018: International Journal of Occupational Safety and Ergonomics: JOSE
https://www.readbyqxmd.com/read/29792545/an-update-on-quality-control-for-the-pfa-100-pfa-200
#11
Emmanuel J Favaloro, Roslyn Bonar
Testing of platelet function comprises a crucial element of hemostasis assessment, particularly for investigations into bleeding and/or bruising. The Platelet Function Analyzer (PFA)-100 is the most utilized primary hemostasis-screening test system available, as recently remodeled/upgraded to the PFA-200. Internal quality control (IQC) and external quality assessment (EQA) (including proficiency testing) represent critical elements of ensuring test practice quality. Although true for all tests, IQC and EQA are logistically challenging for platelet function testing, inclusive of the PFA-100/200...
May 24, 2018: Platelets
https://www.readbyqxmd.com/read/29792476/a-mixed-methods-investigation-into-the-perspectives-on-mental-health-and-professional-treatment-among-former-system-youth-with-mood-disorders
#12
Michelle R Munson, Sarah Carter Narendorf, Shelly Ben-David, Andrea Cole
Research has shown that how people think about their health (or illnesses) shapes their help-seeking behavior. In this mixed-methods study, we employed a simultaneous concurrent design to explore the perceptions of mental illness among an understudied population: marginalized young adults. Participants were 60 young adults (ages 18-25) who had experienced mood disorders and used multiple public systems of care during their childhoods. Semistructured interviews were conducted to understand participants' illness and treatment experiences during the transition to adulthood...
May 24, 2018: American Journal of Orthopsychiatry
https://www.readbyqxmd.com/read/29792441/human-memory-reconsolidation-a-guiding-framework-and-critical-review-of-the-evidence
#13
James W B Elsey, Vanessa A Van Ast, Merel Kindt
Research in nonhuman animals suggests that reactivation can induce a transient, unstable state in a previously consolidated memory, during which the memory can be disrupted or modified, necessitating a process of restabilization in order to persist. Such findings have sparked a wave of interest into whether this phenomenon, known as reconsolidation, occurs in humans. Translating research from animal models to human experiments and even to clinical interventions is an exciting prospect, but amid this excitement, relatively little work has critically evaluated and synthesized existing research regarding human memory reconsolidation...
May 24, 2018: Psychological Bulletin
https://www.readbyqxmd.com/read/29792341/our-experience-with-using-a-uniform-prophylactic-protocol-in-neurosurgery-surgical-site-infection-did-not-occur-in-272-operations
#14
Arash Fattahi, Amin Jahanbakhshi, Morteza Taheri, Akbar Mehrizi, Mehdi Chavoshinejad
PURPOSE: Surgical site infection (SSI) is a source of concern in any surgical procedure. Although studies with high numbers of patients are available, most of these studies were performed by different surgeons and the exact anti-SSI protocol is not mentioned or is not homogeneous in all patients. MATERIALS AND METHODS: We present the results of 272 cases where SSI was successfully prevented in our neurosurgical units and in this study we explain our institutional protocol for achieving this positive result...
May 24, 2018: British Journal of Neurosurgery
https://www.readbyqxmd.com/read/29792088/experimental-evaluation-of-ontology-based-hiv-aids-frequently-asked-question-retrieval-system
#15
Yirsaw Ayalew, Barbara Moeng, Gontlafetse Mosweunyane
This study presents the results of experimental evaluations of an ontology-based frequently asked question retrieval system in the domain of HIV and AIDS. The main purpose of the system is to provide answers to questions on HIV/AIDS using ontology. To evaluate the effectiveness of the frequently asked question retrieval system, we conducted two experiments. The first experiment focused on the evaluation of the quality of the ontology we developed using the OQuaRE evaluation framework which is based on software quality metrics and metrics designed for ontology quality evaluation...
May 1, 2018: Health Informatics Journal
https://www.readbyqxmd.com/read/29791785/expressed-exome-capture-sequencing-eecseq-a-method-for-cost-effective-exome-sequencing-for-all-organisms
#16
Jonathan B Puritz, Katie E Lotterhos
Exome capture is an effective tool for surveying the genome for loci under selection. However, traditional methods require annotated genomic resources. Here, we present a method for creating cDNA probes from expressed mRNA, which are then used to enrich and capture genomic DNA for exon regions. This approach, called "EecSeq", eliminates the need for costly probe design and synthesis. We tested EecSeq in the eastern oyster, Crassostrea virginica, using a controlled exposure experiment. Four adult oysters were heat shocked at 36° C for 1 hour along with four control oysters kept at 14° C...
May 23, 2018: Molecular Ecology Resources
https://www.readbyqxmd.com/read/29791771/minimal-information-about-an-immuno-peptidomics-experiment-miaipe
#17
Jennie R Lill, Peter A van Veelen, Stefan Tenzer, Arie Admon, Etienne Caron, Josh Elias, Albert J R Heck, Miguel Marcilla, Fabio Marino, Markus Müller, Bjoern Peters, Anthony Purcell, Alessandro Sette, Theo Sturm, Nicola Ternette, Juan Antonio Vizcaíno, Michal Bassani-Sternberg
Minimal Information about an Immuno-Peptidomics Experiment (MIAIPE) is an initiative of the members of the Human Immuno-Peptidome Project (HIPP), an international program organized by the Human Proteome Organization (HUPO). The aim of the MIAIPE guidelines is to deliver technical guidelines representing the minimal information required to sufficiently support the evaluation and interpretation of immunopeptidomics experiments. The MIAIPE document has been designed to report essential information about sample preparation, mass spectrometric measurement and associated mass spectrometry (MS)-related bioinformatics aspects that are unique to immunopeptidomics and may not be covered by the general proteomics MIAPE (Minimal Information About a Proteomics Experiment) guidelines...
May 23, 2018: Proteomics
https://www.readbyqxmd.com/read/29791765/resources-for-work-related-well-being-a-qualitative-study-about-healthcare-employees-experiences-of-relationships-at-work
#18
Sophie Schön Persson, Petra Nilsson Lindström, Pär Pettersson, Marie Nilsson, Kerstin Blomqvist
AIMS AND OBJECTIVES: The aim of this study was to explore municipal healthcare employees' experiences of relationships with care recipients and colleagues. The specific research questions were when do the relationships enhance well-being, and what prerequisites are needed for such relationships to occur?. BACKGROUND: Employees in health and social care for older people often depict their work in negative terms, and they often take a high number of sick leaves. Despite the heavy workload, other employees express well-being at work and highlight social relationships as one reason for this...
May 23, 2018: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/29791585/protective-effect-and-mechanism-of-lactobacillus-on-cerebral-ischemia-reperfusion-injury-in-rats
#19
Shi Wanchao, Ma Chen, Su Zhiguo, Xie Futang, Shi Mengmeng
The present study was designed to investigate the protective effects and mechanism of inactivated lactobacillus (ILA) on cerebral ischemia reperfusion injury (CIRI) in rats. In this experiment, 30 male Sprague Dawley rats were randomly divided into control group, IRI groups, and ILA group. A middle cerebral artery occlusion and reperfusion model was prepared. The rats were killed after 24 hours of recovery of blood flow of cerebral ischemia resulting from 60-min occlusion. The cerebral infarction volume and neurological scores were assayed by staining and behavioral observation...
2018: Brazilian Journal of Medical and Biological Research, Revista Brasileira de Pesquisas Médicas e Biológicas
https://www.readbyqxmd.com/read/29791401/investigation-of-index-change-in-compression-molding-of-as-40-se-50-s-10-chalcogenide-glass
#20
Lin Zhang, Wenchen Zhou, Neil J Naples, Allen Y Yi
Chalcogenide glasses are emerging as alternative materials for low-cost and high-volume glass molding processes for infrared optics. In precision glass molding, it is well documented that the refractive index variation in the molded elements can lead to substantial amounts of aberrations. The variation has such a significant effect that the optical designs with molded lenses need to be carefully considered and compensated for index variation to achieve targeted optical performance. This research is aimed to evaluate the refractive index change of a chalcogenide glass during the molding process by both finite element method-based simulation and optical experiment...
May 20, 2018: Applied Optics
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