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https://www.readbyqxmd.com/read/29053831/effect-of-dietary-fiber-levels-on-performance-gizzard-development-intestinal-morphology-and-nutrient-utilization-in-meat-ducks-from-1-to-21-days-of-age
#1
H Y Han, K Y Zhang, X M Ding, S P Bai, Y H Luo, J P Wang, Q F Zeng
The objective of this experiment was to determine the effects of dietary fiber levels on growth performance, gizzard development, intestinal morphology, and nutrient utilization in Cherry Valley meat ducks. In total, 720 1-day-old ducklings were fed with starter diets (120 ducklings, 8 pens of 15 ducklings, on each diet) containing 6 levels of crude fiber (CF, 1.46, 3.09, 4.15, 6.18, 7.52, and 9.03%, based on analysis) for 21 d. Then, on d 22, ducks fed all of the starter diets were transferred to a grower diet (containing 4% CF) to examine the residual effect of starter dietary fiber levels until 35 d...
October 10, 2017: Poultry Science
https://www.readbyqxmd.com/read/29053416/imaging-of-integrin-%C3%AE-v%C3%AE-3-expression-in-lung-cancers-and-brain-tumors-using-single-photon-emission-computed-tomography-with-a-novel-radiotracer-99m-tc-ida-d-c-rgdfk-2
#2
Yoo Sung Song, Hyun Soo Park, Byung Chul Lee, Jae Ho Jung, Ho-Young Lee, Sang Eun Kim
Integrin αvβ3 is a molecular marker for the estimation of tumor angiogenesis and is an imaging target for radiolabeled Arg-Gly-Asp (RGD) peptides. In this study, the authors investigated the clinical efficacy and safety of a novel radiolabeled RGD peptide, (99m)Tc-IDA-D-[c(RGDfK)]2, for the imaging of integrin αvβ3 expression, as a measure of tumor angiogenesis in lung cancers and brain tumors. Five patients with lung cancers and seven with brain tumors underwent (99m)Tc-IDA-D-[c(RGDfK)]2 single-photon emission computed tomography (SPECT) imaging...
October 2017: Cancer Biotherapy & Radiopharmaceuticals
https://www.readbyqxmd.com/read/29052109/assessments-of-opportunities-to-improve-antibiotic-prescribing-in-an-emergency-department-a-period-prevalence-survey
#3
Tristan T Timbrook, Aisling R Caffrey, Anais Ovalle, Maya Beganovic, William Curioso, Melissa Gaitanis, Kerry L LaPlante
INTRODUCTION: Approximately 30% of all outpatient antimicrobials are inappropriately prescribed. Currently, antimicrobial prescribing patterns in emergency departments (ED) are not well described. Determining inappropriate antimicrobial prescribing patterns and opportunities for interventions by antimicrobial stewardship programs (ASP) are needed. METHODS: A retrospective chart review was performed among a random sample of non-admitted, adult patients who received an antimicrobial prescription in the ED from January 1 to December 31, 2015...
October 19, 2017: Infectious Diseases and Therapy
https://www.readbyqxmd.com/read/29051138/effectiveness-of-two-web-based-interventions-for-chronic-cancer-related-fatigue-compared-to-an-active-control-condition-results-of-the-fitter-na-kanker-randomized-controlled-trial
#4
Fieke Z Bruggeman-Everts, Marije D J Wolvers, Rens van de Schoot, Miriam M R Vollenbroek-Hutten, Marije L Van der Lee
BACKGROUND: Approximately one third of all patients who have been successfully treated for cancer suffer from chronic cancer-related fatigue (CCRF). Effective and easily accessible interventions are needed for these patients. OBJECTIVE: The current paper reports on the results of a 3-armed randomized controlled trial investigating the clinical effectiveness of two different guided Web-based interventions for reducing CCRF compared to an active control condition...
October 19, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/29049966/performance-comparison-of-secondary-and-tertiary-treatment-systems-for-treating-antibiotic-resistance
#5
Manisha Lamba, Shaikh Ziauddin Ahammad
Rapid emergence of antibiotic resistance (AR) in developing countries is posing a greater health risk and increasing the global disease burden. AR proliferation mediated by treated/untreated discharges from sewage treatment plants (STPs) is a prime public health concern. Efficient sewage treatment is among our key defenses against the dissemination of infectious diseases. The present study aims to estimate the efficiency of aerobic [activated sludge process (ASP) and modified trickling filter (MTF)] and anaerobic reactors (anaerobic flow-through reactor) along with the three disinfection techniques (UV, ozone and chlorination) in reducing ARB and ARGs present in the domestic sewage...
October 12, 2017: Water Research
https://www.readbyqxmd.com/read/29048101/gallic-acid-inhibits-the-growth-of-calf-pulmonary-arterial-endothelial-cells-through-cell-death-and-glutathione-depletion
#6
Woo Hyun Park
Gallic acid (GA) exhibits a number of cellular effects, including apoptosis, which is associated with oxidative stress. The present study investigated the effects of GA on calf pulmonary arterial endothelial cell (CPAEC) growth and death, along with the levels of reactive oxygen species (ROS) and glutathione (GSH). GA treatment inhibited the growth of CPAECs at 24 h, and the half‑maximal inhibitory concentration (IC50) value of GA was ~30 µM. GA treatment also induced cell death, which was accompanied by a loss of mitochondrial membrane potential (ΔѰm)...
September 21, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29045441/comparability-of-activity-monitors-used-in-asian-and-western-country-studies-for-assessing-free-living-sedentary-behaviour
#7
Satoshi Kurita, Shohei Yano, Kaori Ishii, Ai Shibata, Hiroyuki Sasai, Yoshio Nakata, Noritoshi Fukushima, Shigeru Inoue, Shigeho Tanaka, Takemi Sugiyama, Neville Owen, Koichiro Oka
This study aims to compare the outputs of the waist-worn Active style Pro HJA-350IT (ASP; used in studies with Asian populations), the waist-worn ActiGragh™GT3X+ using the normal filter (GT3X+) and the thigh-worn activPAL3 (AP) in assessing adults' sedentary behaviour (total sedentary time, number of breaks) under free-living conditions. Fifty healthy workers wore the three monitors simultaneously during their waking hours on two days, including a work day and a non-work day. Valid data were at least 10 hours of wearing time, and the differences between monitors on the sedentary outputs using the AP as criterion measurement were analyzed by ANOVA...
2017: PloS One
https://www.readbyqxmd.com/read/29043149/pre-b-acute-lymphoblastic-leukemia-with-t-1-19-in-an-adult-initially-presenting-as-hematuria-and-bilateral-renal-enlargement-a%C3%A2-case-report-and-literature-review
#8
Jian Wu, Xiao-Ling Pi, Zhi-Bin Ye
Although pre-B acute lymphoblastic leukemia (ALL) is the most common type of renal leukemic infiltration; the renal infiltration with leukemia cells as the initial manifestation of leukemia is very rare. Translocation (1;19)(q23;p13) is one of the most common chromosomal abnormalities in patients with ALL and is observed in 5 - 6% of children with pre-B ALL. However, the incidence of t(1;19) in adults is lower, not exceeding 3%, and the prognosis of adult patients is usually poor. Herein, we report a 52-year-old female patient with pre-B ALL who initially presented as bilateral renal enlargement...
2017: Clin Nephrol Case Stud
https://www.readbyqxmd.com/read/29041421/dynamic-three-dimensional-multifocal-spots-in-high-numerical-aperture-objectives
#9
Linwei Zhu, Rui Yang, Dawei Zhang, Junjie Yu, Jiannong Chen
Multifocal spots in high numerical-aperture (NA) objectives has emerged as a rapid, parallel, and multi-location method in a multitude of applications. However, the typical method used for forming three-dimensional (3D) multifocal spots based on iterative algorithms limits the potential applications. We demonstrate a non-iterative method using annular subzone phases (ASPs) that are composed of many annular subareas in which phase-only distributions with different 3D displacements are filled. The dynamic 3D multifocal spots with controllable position of each focal spot in the focal volume of the objective are created using the ASPs...
October 2, 2017: Optics Express
https://www.readbyqxmd.com/read/29036735/facile-synthesis-and-characterization-of-l-aspartic-acid-coated-iron-oxide-magnetic-nanoparticles-ionps-for-biomedical-applications
#10
Marziyeh Salehiabar, Hamed Nosrati, Soodabeh Davaran, Hossein Danafar, Hamidreza Kheiri Manjili
Natural L-aspartic acid coated iron oxide magnetic nanoparticles (Asp@IONPs) were prepared by a one pot, in-situ and green co-precipitation method in an aqueous medium. Functionalized iron oxide magnetic nanoparticles (IONPs) were characterized by Vibrating Sample Magnetometer (VSM), X-ray diffraction (XRD), differential scanning calorimetry (DSC), Fourier transform infrared spectroscopy (FTIR), Scanning electron microscopy (SEM) and Transmission electron microscopy (TEM) techniques. Cellular toxicity of IONPs was also investigated on HEK-293 cell lines...
October 16, 2017: Drug Research
https://www.readbyqxmd.com/read/29032783/targeted-metabolomics-new-insights-into-pathobiology-of-retained-placenta-in-dairy-cows-and-potential-risk-biomarkers
#11
E Dervishi, G Zhang, R Mandal, D S Wishart, B N Ametaj
A targeted quantitative metabolomics approach was used to study temporal changes of serum metabolites in cows that normally released their fetal membranes and those that retained the placenta. We identified and measured serum concentrations of 128 metabolites including amino acids, acylcarnitines, biogenic amines, glycerophospholipids, sphingolipids and hexose at -8 and -4 weeks before parturition, during the week of retained placenta (RP) diagnosis, and at +4 and +8 weeks after parturition. In addition, we aimed at identifying metabolite signatures of pre-RP in the serum that might be used as predictive biomarkers for risk of developing RP in dairy cows...
October 16, 2017: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/29032653/bacterial-hormone-sensitive-lipases-bhsls-emerging-enzymes-for-biotechnological-applications
#12
REVIEW
T Doohun Kim
Lipases are important enzymes with biotechnological applications in dairy, detergent, food, fine chemicals, and pharmaceutical industries. Specifically, hormone-sensitive lipase (HSL) is an intracellular lipase that can be stimulated by several hormones such as catecholamine, glucagon, and adrenocorticotropic hormone (ACTH). Bacterial hormone-sensitive lipases (bHSLs), which are homologous to the C-terminal domain of HSL, have α/β-hydrolase fold with a catalytic triad composed of His, Asp, and Ser. These bHSLs could be used for a wide variety of industrial applications because of their high activity, broad substrate specificity, and remarkable stability...
October 14, 2017: Journal of Microbiology and Biotechnology
https://www.readbyqxmd.com/read/29031804/transcriptional-response-after-exposure-to-domoic-acid-producing-pseudo-nitzschia-in-the-digestive-gland-of-the-mussel-mytilus-galloprovincialis
#13
Antonio J Pazos, Pablo Ventoso, Roi Martínez-Escauriaza, M Luz Pérez-Parallé, Juan Blanco, Juan C Triviño, José L Sánchez
Bivalve molluscs are filter feeding species that can accumulate biotoxins in their body tissues during harmful algal blooms. Amnesic Shellfish Poisoning (ASP) is caused by species of the diatom genus Pseudo-nitzschia, which produces the toxin domoic acid. The Mytilus galloprovincialis digestive gland transcriptome was de novo assembled based on the sequencing of 12 cDNA libraries, six obtained from control mussels and six from mussels naturally exposed to domoic acid-producing diatom Pseudo-nitzschia australis...
October 11, 2017: Toxicon: Official Journal of the International Society on Toxinology
https://www.readbyqxmd.com/read/29031431/implementing-an-antibiotic-stewardship-program-at-a-long-term-acute-care-hospital-in-detroit-michigan
#14
Ammara Mushtaq, Reda A Awali, Suganya Chandramohan, Amar Krishna, Caitlin Biedron, Olufemi Jegede, Teena Chopra
BACKGROUND: The objective of the study was to assess health care providers' (HCPs) knowledge and attitude toward antimicrobial resistance (AMR) and implement an antimicrobial stewardship program (ASP) in a long-term acute care hospital (LTACH). METHODS: A questionnaire on antibiotic use and resistance was administered to HCP in an LTACH in Detroit, Michigan, between August 2011 and October 2011. Concurrently, a retrospective review of common antibiotic prescription practices and costs was conducted...
October 11, 2017: American Journal of Infection Control
https://www.readbyqxmd.com/read/29030429/activating-mutations-in-quorum-sensing-regulator-rgg2-and-its-conformational-flexibility-in-the-absence-of-an-intermolecular-disulfide-bond
#15
Reid V Wilkening, Glenn C Capodagli, Atul Khataokar, Kaitlyn M Tylor, Matthew B Neiditch, Michael J Federle
Rap/Rgg/NprR/PlcR/PrgX (RRNPP) quorum-sensing systems use extracellular peptide pheromones that are detected by cytoplasmic receptors to regulate gene expression in firmicute bacteria. Rgg-type receptors are allosterically regulated through direct pheromone binding to control transcriptional activity; however, the receptor activation mechanism remains poorly understood. Previous work has identified a disulfide bond between Cys-45 residues within the homodimer interface of Rgg2 from Streptococcus dysgalactiae (Rgg2Sd)...
October 13, 2017: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/29030107/ammodytin-l-is-the-main-cardiotoxic-component-of-the-vipera-ammodytes-ammodytes-venom
#16
Svjetlana Karabuva, Boris Lukšić, Ivica Brizić, Zorica Latinović, Adrijana Leonardi, Igor Križaj
Venom of the nose-horned viper (V. a. ammodytes) as also venoms of some related European viperids can induce also cardiotoxic effects in mammals. In this work we demonstrated that the protein in the V. a. ammodytes venom acting on heart is a myotoxic secreted phospholipase A2 analogue ammodytin L (AtnL). In the isolated perfused rat heart AtnL induced significant and irreversible cardiotoxicity characterized by atrioventricular (AV) blockade. This venom protein induced appearance of high levels of creatine kinase, lactate dehydrogenase, aspartate aminotransferase and troponin I in the sinus effluent of the isolated heart, indicative for myocardial damage, which is obviously the primary cause of its cardiotoxic action...
October 10, 2017: Toxicon: Official Journal of the International Society on Toxinology
https://www.readbyqxmd.com/read/29028546/enzymatic-characterization-and-crystal-structure-analysis-of-chlamydomonas-reinhardtii-dehydroascorbate-reductase-and-their-implications-for-oxidative-stress
#17
Hsin-Yang Chang, Shu-Tseng Lin, Tzu-Ping Ko, Shu-Mei Wu, Tsen-Hung Lin, Yu-Ching Chang, Kai-Fa Huang, Tse-Min Lee
Dehydroascorbate reductase (DHAR) is a key enzyme for glutathione (GSH)-dependent reduction of dehydroascorbate (DHA) to recycled ascorbate (AsA) in plants, and plays a major role against the toxicity of reactive oxygen species (ROS). Previously, we proposed that the increase of AsA regeneration via enhanced DHAR activity modulates the ascorbate-glutathione cycle activity against photooxidative stress in Chlamydomonas reinhardtii. In the present work, we use site-directed mutagenesis and crystal structure analysis to elucidate the molecular basis of how C...
October 3, 2017: Plant Physiology and Biochemistry: PPB
https://www.readbyqxmd.com/read/29027162/how-to-combine-chip-with-qpcr
#18
Patrik Asp
Chromatin immunoprecipitation (ChIP) coupled with quantitative PCR (qPCR) has in the last 15 years become a basic mainstream tool in genomic research. Numerous commercially available ChIP kits, qPCR kits, and real-time PCR systems allow for quick and easy analysis of virtually anything chromatin-related as long as there is an available antibody. However, the highly accurate quantitative dimension added by using qPCR to analyze ChIP samples significantly raises the bar in terms of experimental accuracy, appropriate controls, data analysis, and data presentation...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29026283/outcomes-study-between-femtosecond-laser-assisted-cataract-surgery-and-conventional-phacoemulsification-surgery-using-an-active-fluidics-system
#19
Wilson Takashi Hida, Patrick Frenzel Tzelikis, César Vilar, Mario Augusto Pereira Dias Chaves, Antônio Francisco Pimenta Motta, Pedro Carlos Carricondo, Bruna Vieira Ventura, Renato Ambrosio, Walton Nosé, Milton Ruiz Alves
PURPOSE: The purpose of this study was to compare intraoperative parameters between femtosecond laser-assisted cataract surgery (FLACS) and conventional phacoemulsification using Centurion(®) Vision System with Active Fluidics. SETTING: This study was performed at Brasília Ophthalmologic Hospital, Brasília, Federal District, Brazil. PATIENTS AND METHODS: This was a prospective randomized comparative study. Patients with the diagnosis of cataract and surgical extraction programmed were divided into two groups: conventional phacoemulsification and FLACS...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29025237/the-role-of-injectables-in-aesthetic-surgery-financial-implications
#20
Bryson G Richards, William F Schleicher, Gehaan F D'Souza, Raymond Isakov, James E Zins
Background: The plastic surgeon competes with both core and noncore physicians and surgeons for traditional cosmetic procedures. In 2007, the American Society for Aesthetic Plastic Surgery (ASAPS) and the American Society of Plastic Surgeons (ASPS) joined efforts to form a Cosmetic Medicine Task Force to further analyze this trend. Objectives: Our objective is to document and quantify the patient capture and total collections generated in a single surgeon's practice exclusive from Botulinum Toxin A and filler injections over a 10-year period...
October 1, 2017: Aesthetic Surgery Journal
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