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Iron AND Child development

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https://www.readbyqxmd.com/read/28104188/maternal-multiple-micronutrient-supplementation-and-other-biomedical-and-socioenvironmental-influences-on-children-s-cognition-at-age-9-12-years-in-indonesia-follow-up-of-the-summit-randomised-trial
#1
Elizabeth L Prado, Susy K Sebayang, Mandri Apriatni, Siti R Adawiyah, Nina Hidayati, Ayuniarti Islamiyah, Sudirman Siddiq, Benyamin Harefa, Jarrad Lum, Katherine J Alcock, Michael T Ullman, Husni Muadz, Anuraj H Shankar
BACKGROUND: Brain and cognitive development during the first 1000 days from conception are affected by multiple biomedical and socioenvironmental determinants including nutrition, health, nurturing, and stimulation. An improved understanding of the long-term influence of these factors is needed to prioritise public health investments to optimise human development. METHODS: We did a follow-up study of the Supplementation with Multiple Micronutrients Intervention Trial (SUMMIT), a double-blind, cluster-randomised trial of maternal supplementation with multiple micronutrients (MMN) or iron and folic acid (IFA) in Indonesia...
February 2017: Lancet Global Health
https://www.readbyqxmd.com/read/28099398/utilizing-a-novel-mobile-health-selfie-application-to-improve-compliance-to-iron-chelation-in-pediatric-patients-receiving-chronic-transfusions
#2
Sarah Leonard, Lindsay M Anderson, Jude Jonassaint, Charles Jonassaint, Nirmish Shah
Iron chelation therapy can prevent iron overload for pediatric patients with sickle cell disease and β-thalassemia major; however, adherence is suboptimal. Therefore, we developed an intensive training program (ITP), to improve medication management and disease knowledge. The objectives were to determine feasibility of the ITP and its preliminary impact on adherence, disease knowledge, and health outcomes. Pediatric patients were recruited to participate in the ITP over a 90-day period and were followed for 6 months...
January 17, 2017: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/28053670/the-complete-genome-sequence-of-cronobacter-sakazakii-atcc-29544-t-a-food-borne-pathogen-isolated-from-a-child-s-throat
#3
Seongok Kim, You-Tae Kim, Hyunjin Yoon, Ju-Hoon Lee, Sangryeol Ryu
BACKGROUND: Cronobacter sakazakii is an emerging opportunistic pathogen that is associated with rare but life-threatening cases of severe diseases: meningitis, necrotizing enterocolitis, and sepsis in premature and full-term infants. However, the pathogenesis mechanism of this pathogen remains largely unknown. To determine its pathogenesis at the genomic level, the genome of C. sakazakii ATCC 29544(T) was completely sequenced and analyzed. RESULTS: The genomic DNA, containing a circular chromosome and three plasmids, is composed of 4,511,265 bp with a GC content of 56...
2017: Gut Pathogens
https://www.readbyqxmd.com/read/28031374/large-scale-behavior-change-initiative-for-infant-and-young-child-feeding-advanced-language-and-motor-development-in-a-cluster-randomized-program-evaluation-in-bangladesh
#4
Edward A Frongillo, Phuong H Nguyen, Kuntal K Saha, Tina Sanghvi, Kaosar Afsana, Raisul Haque, Jean Baker, Marie T Ruel, Rahul Rawat, Purnima Menon
BACKGROUND: Promoting adequate nutrition through interventions to improve infant and young child feeding (IYCF) has the potential to contribute to child development. OBJECTIVE: We examined whether an intensive intervention package that was aimed at improving IYCF at scale through the Alive & Thrive initiative in Bangladesh also advanced language and gross motor development, and whether advancements in language and gross motor development were explained through improved complementary feeding...
February 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28008727/nutrient-composition-of-premixed-and-packaged-complementary-foods-for-sale-in-low-and-middle-income-countries-lack-of-standards-threatens-infant-growth
#5
William A Masters, Marc D Nene, Winnie Bell
Premixed flours for infant porridge are increasingly produced and sold in developing countries to complement continued breastfeeding. Such complementary food (CF) products have known efficacy against malnutrition in children from 6 to 24 months of age, but ingredient ratios and production processes may vary. This study provides the first systematic measurement of their actual nutrient composition. We purchased samples of 108 premixed CF products in 22 low- and middle-income countries, and commissioned blind laboratory measurement of each product's macronutrients and micronutrients...
December 22, 2016: Maternal & Child Nutrition
https://www.readbyqxmd.com/read/28000692/impact-of-maternal-antenatal-and-birth-associated-factors-on-iron-stores-at-birth-data-from-a-prospective-maternal-infant-birth-cohort
#6
E K McCarthy, L C Kenny, J O'B Hourihane, A D Irvine, D M Murray, M E Kiely
BACKGROUND/OBJECTIVES: Low serum ferritin concentrations at birth, which reflect neonatal iron stores, track through to early childhood and have been associated with poorer neurodevelopmental outcomes. We aimed to identify maternal, antenatal and birth-associated factors that influence iron stores at birth in a prospective maternal-infant birth cohort. SUBJECTS/METHODS: In a population-based, longitudinal, birth cohort in Ireland, 413 maternal-infant dyads with prospectively collected lifestyle and clinical data from 15 weeks' gestation had umbilical cord serum ferritin concentrations measured...
December 21, 2016: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/27942845/in-vitro-assessment-of-iron-availability-from-commercial-young-child-formulae-supplemented-with-prebiotics
#7
Tatiana Christides, Julia Clark Ganis, Paul Anthony Sharp
PURPOSE: Iron is essential for development and growth in young children; unfortunately, iron deficiency (ID) is a significant public health problem in this population. Young Child Formulae (YCF), milk-derived products fortified with iron and ascorbic acid (AA, an enhancer of iron absorption) may be good sources of iron to help prevent ID. Furthermore, some YCF are supplemented with prebiotics, non-digestible carbohydrates suggested to enhance iron bioavailability. The aim of our study was to evaluate iron bioavailability of YCF relative to prebiotic and AA concentrations...
December 9, 2016: European Journal of Nutrition
https://www.readbyqxmd.com/read/27940685/prenatal-iron-deficiency-neonatal-ferritin-and-infant-cognitive-function
#8
Michael O Mireku, Leslie L Davidson, Michael J Boivin, Romeo Zoumenou, Achille Massougbodji, Michel Cot, Florence Bodeau-Livinec
OBJECTIVE: To investigate the impact of prenatal maternal iron deficiency (ID) on cord blood serum ferritin (CBSF) concentration and infant cognitive and motor development. METHODS: Our prospective cohort study included 636 mother-singleton child pairs from 828 eligible pregnant women who were enrolled during their first antenatal care (ANC) visit in Allada, Benin, into a clinical trial comparing the efficacy of mefloquine and sulfadoxine-pyrimethamine. Venous blood samples of women were assessed for ferritin and hemoglobin concentrations at the first and second ANC visits (occurring at least 1-month apart) and at delivery...
December 2016: Pediatrics
https://www.readbyqxmd.com/read/27928745/perceived-emotion-genuineness-normative-ratings-for-popular-facial-expression-stimuli-and-the-development-of-perceived-as-genuine-and-perceived-as-fake-sets
#9
Amy Dawel, Luke Wright, Jessica Irons, Rachael Dumbleton, Romina Palermo, Richard O'Kearney, Elinor McKone
In everyday social interactions, people's facial expressions sometimes reflect genuine emotion (e.g., anger in response to a misbehaving child) and sometimes do not (e.g., smiling for a school photo). There is increasing theoretical interest in this distinction, but little is known about perceived emotion genuineness for existing facial expression databases. We present a new method for rating perceived genuineness using a neutral-midpoint scale (-7 = completely fake; 0 = don't know; +7 = completely genuine) that, unlike previous methods, provides data on both relative and absolute perceptions...
December 7, 2016: Behavior Research Methods
https://www.readbyqxmd.com/read/27916873/the-effect-of-low-dose-iron-and-zinc-intake-on-child-micronutrient-status-and-development-during-the-first-1000-days-of-life-a-systematic-review-and-meta-analysis
#10
REVIEW
Nicolai Petry, Ibironke Olofin, Erick Boy, Moira Donahue Angel, Fabian Rohner
Adequate supply of micronutrients during the first 1000 days is essential for normal development and healthy life. We aimed to investigate if interventions administering dietary doses up to the recommended nutrient intake (RNI) of iron and zinc within the window from conception to age 2 years have the potential to influence nutritional status and development of children. To address this objective, a systematic review and meta-analysis of randomized and quasi-randomized fortification, biofortification, and supplementation trials in women (pregnant and lactating) and children (6-23 months) delivering iron or zinc in doses up to the recommended nutrient intake (RNI) levels was conducted...
November 30, 2016: Nutrients
https://www.readbyqxmd.com/read/27852523/anemia-offers-stronger-protection-than-sickle-cell-trait-against-the-erythrocytic-stage-of-falciparum-malaria-and-this-protection-is-reversed-by-iron-supplementation
#11
M M Goheen, R Wegmüller, A Bah, B Darboe, E Danso, M Affara, D Gardner, J C Patel, A M Prentice, C Cerami
BACKGROUND: Iron deficiency causes long-term adverse consequences for children and is the most common nutritional deficiency worldwide. Observational studies suggest that iron deficiency anemia protects against Plasmodium falciparum malaria and several intervention trials have indicated that iron supplementation increases malaria risk through unknown mechanism(s). This poses a major challenge for health policy. We investigated how anemia inhibits blood stage malaria infection and how iron supplementation abrogates this protection...
December 2016: EBioMedicine
https://www.readbyqxmd.com/read/27837349/comparison-of-body-composition-and-nutrients-deficiencies-between-portuguese-rink-hockey-players
#12
Maria-Raquel G Silva, Hugo-Henrique Silva
: We evaluated dietary intake and body composition of child and adolescent rink-hockey players and controls. Seventy-two male rink-hockey players (38 children and 34 adolescents) and 79 male controls (43 children and 36 adolescents) were evaluated in order to collect training data, detailed dietary intake and body composition. Rink-hockey players presented significantly lower body fat (BF) and higher fat-free mass (FFM) than controls. Mean intakes of carbohydrate and protein were considered to be adequate, but mean intakes of fat were above the recommended levels in athletes...
January 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/27830277/a-longitudinal-study-of-iron-status-during-pregnancy-and-the-risk-of-gestational-diabetes-findings-from-a-prospective-multiracial-cohort
#13
Shristi Rawal, Stefanie N Hinkle, Wei Bao, Yeyi Zhu, Jagteshwar Grewal, Paul S Albert, Natalie L Weir, Michael Y Tsai, Cuilin Zhang
AIMS/HYPOTHESIS: The aim of this study was to prospectively and longitudinally investigate maternal iron status during early to mid-pregnancy, and subsequent risk of gestational diabetes mellitus (GDM), using a comprehensive panel of conventional and novel iron biomarkers. METHODS: A case-control study of 107 women with GDM and 214 controls (matched on age, race/ethnicity and gestational week during blood collection) was conducted within the the Eunice Kennedy Shriver National Institute of Child Health and Human Development Fetal Growth Studies-Singleton Cohort (2009-2013), a prospective and multiracial pregnancy cohort...
February 2017: Diabetologia
https://www.readbyqxmd.com/read/27821991/a-study-to-assess-empowerment-of-adolescent-girls-in-terms-of-knowledge-based-life-skills-education-about-child-survival-and-safe-motherhood-practices
#14
A K Choudhary, D M Saxena, Rituja Kaushal
OBJECTIVE: This study has been designed with the intention to bring a substantial change in the mindsets or life skills of adolescent girls at secondary school level regarding their concept of child survival and safe motherhood practices in order to deal effectively with real-life situations. METHODOLOGY: A cross-sectional analytical study was carried out with 538 adolescent girls regarding assessment of their knowledge on variables like correct nutrition, iron-deficiency anemia and its prevention, care during pregnancy, safe birth, skilled birth attendance, breast feeding and complementary feeding practices, child's growth and development issues, immunization, management of common childhood illnesses...
December 2016: Journal of Obstetrics and Gynaecology of India
https://www.readbyqxmd.com/read/27748235/effect-of-maternal-zinc-supplementation-on-the-cardiometabolic-profile-of-peruvian-children-results-from-a-randomized-clinical-trial
#15
M L Mispireta, L E Caulfield, N Zavaleta, M Merialdi, D L Putnick, M H Bornstein, J A DiPietro
Zinc is an essential micronutrient for the development of the fetal renal, cardiovascular and metabolic systems; however, there is limited evidence of its effects on the postnatal cardiometabolic function. In this study, we evaluated the effect of maternal zinc supplementation during pregnancy on the cardiometabolic profile of the offspring in childhood. A total of 242 pregnant women were randomly assigned to receive a daily supplement containing iron+folic acid with or without zinc. A follow-up study was conducted when children of participating mothers were 4...
February 2017: Journal of Developmental Origins of Health and Disease
https://www.readbyqxmd.com/read/27687906/early-nutrition-growth-and-cognitive-development-of-infants-from-birth-to-2%C3%A2-years-in-malaysia-a-study-protocol
#16
Abdul Razak Nurliyana, Zalilah Mohd Shariff, Mohd Nasir Mohd Taib, Wan Ying Gan, Kit-Aun Tan
BACKGROUND: The first 2 years of life is a critical period of rapid growth and brain development. During this period, nutrition and environmental factors play important roles in growth and cognitive development of a child. This report describes the study protocol of early nutrition, growth and cognitive development of infants from birth to 2 years of age. METHODS/DESIGN: This is a prospective cohort study of mothers and infants recruited from government health clinics in Seremban district in Negeri Sembilan, Malaysia...
September 29, 2016: BMC Pediatrics
https://www.readbyqxmd.com/read/27604769/effects-of-prenatal-multiple-micronutrient-supplementation-on-growth-and-cognition-through-2-y-of-age-in-rural-bangladesh-the-jivita-3-trial
#17
Parul Christian, Jeongyong Kim, Sucheta Mehra, Saijuddin Shaikh, Hasmot Ali, Abu Ahmed Shamim, Lee Wu, Rolf Klemm, Alain B Labrique, Keith P West
BACKGROUND: Childhood undernutrition may have prenatal origins, and the impact of prenatal interventions on postnatal growth is not well known. OBJECTIVE: We assessed the effects of prenatal multiple micronutrient (MM) supplementation on child growth and cognitive development. DESIGN: In a cluster-randomized controlled trial in rural Bangladesh, prenatal MM supplementation compared with iron-folic acid (IFA) supplementation was examined for its impact on growth assessed longitudinally from birth up to 24 mo of age (n = 8529) and, in a subsample (n = 734), on cognitive function at 24 mo of age by use of the Bayley scales of infant and toddler development-third edition test...
October 2016: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/27603883/-young-children-toddlers-and-school-age-children
#18
Solange Heller-Rouassant, María Eugenia Flores-Quijano
Cow´s milk represents a very important source of proteins of high biological value and calcium in the child´s diet. The aim of this article is to review the available evidences of its role in nutrition of young children and school age children. Its main benefits are related with effects in linear growth, bone health and oral health, as protein source in early severe malnutrition, and it does not appears to influence metabolic syndrome risk and autism. High protein content in cow´s milk and increased protein consumption by children during the complementary feeding period is associated to the risk of developing a high body mass index and obesity in school-age children; therefore, milk consumption should be mildly restricted during the second year of life and to 480-720 ml/day during the first years of life...
September 2016: Gaceta Médica de México
https://www.readbyqxmd.com/read/27592528/evaluation-of-the-relationship-between-height-and-zinc-copper-iron-calcium-and-magnesium-levels-in-healthy-young-children-in-beijing-china
#19
Yan Yin, Yongjin Li, Qin Li, Ni Jia, Aihua Liu, Zangwen Tan, Qiong Wu, Zhaoyang Fan, Tao Li, Lijun Wang
We evaluated the relationship between child (aged 6-36 months) height and blood zinc, copper, iron, calcium, and magnesium concentrations. We selected 840 children following a physical examination. Weight and supine length or standing height were measured according to the World Health Organization guidelines. Polarographic analysis was used to measure zinc, copper, iron, magnesium, and calcium levels. Differences in heights between groups with low vs. high mineral concentrations, stratified by sex and age, were compared by analysis of variance...
September 5, 2016: Biological Trace Element Research
https://www.readbyqxmd.com/read/27581575/combining-intensive-counseling-by-frontline-workers-with-a-nationwide-mass-media-campaign-has-large-differential-impacts-on-complementary-feeding-practices-but-not-on-child-growth-results-of-a-cluster-randomized-program-evaluation-in-bangladesh
#20
Purnima Menon, Phuong Hong Nguyen, Kuntal Kumar Saha, Adiba Khaled, Tina Sanghvi, Jean Baker, Kaosar Afsana, Raisul Haque, Edward A Frongillo, Marie T Ruel, Rahul Rawat
BACKGROUND: Complementary feeding (CF) contributes to child growth and development, but few CF programs are delivered at scale. Alive & Thrive addressed this in Bangladesh through intensified interpersonal counseling (IPC), mass media (MM), and community mobilization (CM). OBJECTIVE: The objective was to evaluate the impact of providing IPC + MM + CM (intensive) compared with standard nutrition counseling + less intensive MM + CM (nonintensive) on CF practices and anthropometric measurements...
October 2016: Journal of Nutrition
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