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https://www.readbyqxmd.com/read/28944983/oral-prolonged-release-oxycodone-naloxone-for-managing-pain-and-opioid-induced-constipation-a-review-of-the-evidence
#1
REVIEW
Bart J Morlion, Stefan A Mueller-Lissner, Renato Vellucci, Wojciech Leppert, Benoît C Coffin, Sara L Dickerson, Tony O'Brien
BACKGROUND: Opioids provide effective relief from moderate-to-severe pain and should be prescribed as part of a multifaceted approach to pain management when other treatments have failed. Fixed-dose oxycodone/naloxone prolonged-release tablets (OXN PR) were designed to address the opioid class effect of opioid-induced constipation (OIC) by combining the analgesic efficacy of oxycodone with the opioid receptor antagonist, naloxone, which has negligible systemic availability when administered orally...
September 25, 2017: Pain Practice: the Official Journal of World Institute of Pain
https://www.readbyqxmd.com/read/28944686/remission-of-chronic-headache-rates-potential-predictors-and-the-role-of-medication-follow-up-results-of-the-german-headache-consortium-ghc-study
#2
Verena Henning, Zaza Katsarava, Mark Obermann, Susanne Moebus, Sara Schramm
Objectives To estimate remission rates of chronic headache (CH), focusing on potential predictors of headache remission and medication. Methods We used data from the longitudinal population-based German Headache Consortium (GHC) Study (n = 9,944, 18-65 years). Validated questionnaires were used at baseline (t0, 2003-2007, response rate: 55.2%), first follow-up after 1.87 ± 0.39 years (t1, 37.2%) and second follow-up after 3.26 ± 0.60 years (t2, 38.8%) to assess headache type and frequency, use of analgesics and anti-migraine drugs, medication overuse, education, BMI, smoking and alcohol consumption...
January 1, 2017: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/28944633/-process-for-implementing-a-pain-assessment-scale-for-patients-with-brain-injuries-160-description-of-a-project-methodology-based-on-the-integrated-model-of-consultation
#3
Veronique de Goumoens, Francois Decaillet, Amelia Didier, Chantal Montreuil, Karin Diserens, Anne-Sylvie Ramelet
Background : in a neurosurgery unit, nurses selected the Critical Pain Observation Tool (CPOT) based on evidence to assess pain in brain-injured patients. However, months after implementation, nursing managers have observed an underutilization.Objectives : support a care team to overcome the pitfalls encountered during the implementation of the CPOT scale for brain-injured patients in neurosurgery unit.Methods : the Lescarbeau, Payette and St-Arnaud's Integrated Model of Consultation was selected. In addition to a scientific literature review, self-administered questionnaire and three interview guides were developed to gather the views of caregivers...
April 19, 2017: Recherche en Soins Infirmiers
https://www.readbyqxmd.com/read/28944584/resource-reduction-in-pediatric-chest-pain-standardized-clinical-assessment-and-management-plan
#4
Susan F Saleeb, Sarah R McLaughlin, Dionne A Graham, Kevin G Friedman, David R Fulton
OBJECTIVE: Using a Standardized Clinical Assessment and Management Plan (SCAMP) for pediatric patients presenting to clinic with chest pain, we evaluated the cost impact associated with implementation of the care algorithm. Prior to introduction of the SCAMP, we analyzed charges for 406 patients with chest pain, seen in 2009, and predicted 21% reduction of overall charges had the SCAMP methodology been used. The SCAMP recommended an echocardiogram for history, examination, or ECG findings suggestive of a cardiac etiology for chest pain...
September 24, 2017: Congenital Heart Disease
https://www.readbyqxmd.com/read/28944461/hearing-aids-for-mild-to-moderate-hearing-loss-in-adults
#5
REVIEW
Melanie A Ferguson, Pádraig T Kitterick, Lee Yee Chong, Mark Edmondson-Jones, Fiona Barker, Derek J Hoare
BACKGROUND: The main clinical intervention for mild to moderate hearing loss is the provision of hearing aids. These are routinely offered and fitted to those who seek help for hearing difficulties. By amplifying and improving access to sounds, and speech sounds in particular, the aim of hearing aid use is to reduce the negative consequences of hearing loss and improve participation in everyday life. OBJECTIVES: To evaluate the effects of hearing aids for mild to moderate hearing loss in adults...
September 25, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28944405/knowledge-and-attitudes-toward-cancer-pain-management-among-nurses-at-oncology-units
#6
Malek Khalel Alnajar, Muhammad W Darawad, Sandi Sami Alshahwan, Osama A Samarkandi
Nurses have major responsibilities to treat cancer pain in an optimal way. Their knowledge and attitudes are the key to success cancer pain management (CPM) process and impact the outcomes of pain treatment. This study aimed to evaluate the knowledge and attitudes toward CPM among Jordanian nurses working at oncology units. A cross-sectional descriptive design was used to collect data from 135 nurses who were working at four oncology units using Knowledge and Attitudes Survey Regarding Pain. The percentage of correct answers was 51...
September 24, 2017: Journal of Cancer Education: the Official Journal of the American Association for Cancer Education
https://www.readbyqxmd.com/read/28944352/subtraction-radiographic-assessment-of-underlying-dentin-after-partial-carious-dentin-removal-in-primary-teeth
#7
Araya Phonghanyudh, Chayathorn Ruangdit, Suchaya Pornprasertsuk-D Amrongsri, Prathip Phanthumvanit
PURPOSE: To assess the one-year outcome of glass-ionomer cement (GIC) restorations with partial carious dentin removal in primary molars using digital subtraction radiographs. MATERIALS AND METHODS: Children ages 6-8 years were recruited. Forty-nine primary molars with deep carious lesions were studied. The carious dentin was removed at the dentoenamel junction (DEJ) and restored with GIC. Digital radiographs were taken immediately after restoration, and at 6 and 12 months after restoration...
September 21, 2017: Oral Health & Preventive Dentistry
https://www.readbyqxmd.com/read/28944260/post-treatment-survivorship-care-needs-of-spanish-speaking-latinas-with-breast-cancer
#8
Anna María Nápoles, Carmen Ortiz, Jasmine Santoyo-Olsson, Anita L Stewart, Howard E Lee, Ysabel Duron, Niharika Dixit, Judith Luce, Diana J Flores
BACKGROUND: A comprehensive assessment of Spanish-speaking breast cancer survivors' (SSBCS) survivorship needs is lacking. OBJECTIVE: Assess SSBCS' post-treatment symptom management, psychosocial, and informational needs. METHODS: 118 telephone surveys and 25 in-person semi-structured interviews with SSBCS, and semi-structured interviews with 5 support providers and 4 physicians who serve SSBCS from 5 Northern California counties. RESULTS: Surveys identified the most bothersome (bothered by it in the past month "somewhat/quite a bit/a lot") physical symptoms as: joint pain, fatigue, hot flashes, numbness in hands/feet, and vaginal dryness...
2017: Journal of Community and Supportive Oncology
https://www.readbyqxmd.com/read/28944252/anconeus-muscle-pedicle-bone-graft-with-periosteal-coverage-for-osteochondritis-dissecans-of-the-humeral-capitellum
#9
Kozo Shimada, Ko Temporin, Keiichiro Oura, Hiroyuki Tanaka, Ryosuke Noguchi
BACKGROUND: Treatment of advanced osteochondritis dissecans (OCD) of the capitellum is controversial, especially in moderate-sized lesions. PURPOSE: To establish a treatment algorithm for capitellum OCD, we tried to determine the utility of and problems associated with anconeus muscle-pedicle bone graft with periosteal coverage (ABGP) for the treatment of moderate-sized articular OCD defects of the capitellum. STUDY DESIGN: Case series; Level of evidence, 4...
September 2017: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/28944220/determinants-for-further-wishes-for-cosmetic-and-reconstructive-interventions-in-1652-patients-with-surgical-treated-carcinomas-of-the-oral-cavity
#10
Henrik Holtmann, Simon Spalthoff, Nils-Claudius Gellrich, Jörg Handschel, Julian Lommen, Norbert R Kübler, Gertrud Krüskemper, Majeed Rana, Karoline Sander
BACKGROUND: The impairment of the appearance is a major problem for patients with carcinomas of the oral cavity. These patients want to recover their preoperative facial appearance. Some do not realize that this is not always possible and hence develop a desire for further cosmetic and reconstructive surgery (CRS) which often causes psychological problems. METHOD: The desire of patients for CRS (N = 410; 26%) has been acquired in this DÖSAK rehab study including multiple reasons such as medical, functional, aesthetic and psychosocial aspects...
December 2017: Maxillofacial Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28944126/oral-hygiene-practices-and-teeth-cleaning-techniques-among-medical-students
#11
Sajida Naseem, Syeda H Fatima, Haider Ghazanfar, Sana Haq, Najeeb A Khan, Moeez Mehmood, Ali Ghazanfar
Objectives Oral health is essential for general health and quality of life. It is a state of being free from mouth and facial pain, oral and throat cancer, oral infections and sores, periodontal disease, tooth decay, tooth loss, and other diseases and disorders that limit an individual's capacity to bite, chew, smile, and speak; it affects psychosocial well-being too. The objective of our study was to assess teeth cleaning techniques and oral hygiene practices among medical students. Methods The data of the study were collected in two stages...
July 18, 2017: Curēus
https://www.readbyqxmd.com/read/28943529/quisqualis-indica-improves-benign-prostatic-hyperplasia-by-regulating-prostate-cell-proliferation-and-apoptosis
#12
Charith Ub Wijerathne, Hee-Seon Park, Hye-Yun Jeong, Ji-Won Song, Og-Sung Moon, Young-Won Seo, Young-Suk Won, Hwa-Young Son, Jong-Hwan Lim, Sung-Hum Yeon, Hyo-Jung Kwun
Quisqualis indica (QI) has been used for treating disorders such as stomach pain, constipation, and digestion problem. This study was aimed to evaluate the therapeutic efficacy of QI extract on treating benign prostatic hyperplasia (BPH) in LNCaP human prostate cancer cell line and a testosterone-induced BPH rat model. LNCaP cells were treated with QI plus testosterone propionate (TP), and androgen receptor (AR) and prostate specific antigen (PSA) expression levels were assessed by Western blotting. To induce BPH, the rats were subjected to a daily subcutaneous injection of TP (3 mg/kg) for 4 wk...
September 22, 2017: Biological & Pharmaceutical Bulletin
https://www.readbyqxmd.com/read/28943361/developing-a-short-form-of-the-german-barriers-questionnaire-ii-a-validation-study-in-four-steps
#13
Antje Koller, Patrick Jahn
CONTEXT: Patient-related barriers to cancer pain management are most commonly assessed with the Barriers Questionnaire-II (BQII; 27 items). OBJECTIVES: The aim of this study was to develop a valid short form of the BQII-German (BQII-G) to increase usability in clinical routines and reduce patient burden. METHODS: The validation study comprised a stepwise approach. In the first step, the linguistic validated version of the BQII-G was psychometrically tested for internal consistency and factor structure (N=207)...
September 21, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/28943233/unravelling-fibromyalgia-steps-towards-individualized-management
#14
Winfried Häuser, Serge Perrot, Daniel J Clauw, Mary-Ann Fitzcharles
The heterogeneity of the clinical presentation and the pathophysiologic mechanisms associated with fibromyalgia (FM), and the modest results on average for any therapy, call for a more individualized management strategy. Individualized treatment can be based on subgrouping of patients according to associated conditions (mental health problems; chronic overlapping pain conditions; other somatic diseases) or on the disease severity. Categorizing FM as mild, moderate or severe can be based on clinical assessment (e...
September 21, 2017: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/28943073/the-reliability-and-validity-of-a-venezuelan-version-of-the-bath-ankylosing-spondylitis-functional-index-basfi-and-bath-ankylosing-spondylitis-disease-activity-index-basdai
#15
Mayra Rauseo Vera, Luis Arturo Gutiérrez-González, Irama Maldonado, Soham Al Snih
INTRODUCTION: Spondyloarthropathies (SpA) are disabling diseases with a prevalence of 1.9% in the general population. The indices designed for monitoring the disease should be valid, reliable and cross-culturally adapted for decision-making concerning the appropriate treatment. Changing an adjective or pronoun in a self-administered questionnaire could be the big difference in condensing an idea in a few words and transmitting that concept to all those who share the same language. OBJECTIVES: To develop a Venezuelan version of the original English version of the BASDAI/BASFI and to evaluate its reliability and validity in Venezuelan patients with SpA...
September 21, 2017: Reumatología Clinica
https://www.readbyqxmd.com/read/28943009/midterm-and-long-term-follow-up-in-competitive-athletes-undergoing-thoracic-outlet-decompression-for-neurogenic-thoracic-outlet-syndrome
#16
William Shutze, Brad Richardson, Ryan Shutze, Kimberly Tran, Allen Dao, Gerald O Ogola, Allan Young, Greg Pearl
BACKGROUND: Neurogenic thoracic outlet syndrome (NTOS) results from compression of the brachial plexus by the clavicle, first rib, and scalene muscles and may develop secondary to repetitive motion of the upper extremity. Athletes routinely perform repetitive motions, and sports requiring significant arm and shoulder use may put the participant at increased risk for NTOS. Competitive athletes who develop NTOS may require first rib resection and scalenectomy (FRRS) for symptomatic relief...
September 21, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28943002/a-feasibility-double-blind-randomized-placebo-controlled-trial-of-extracorporeal-shockwave-therapy-as-a-novel-treatment-for-intermittent-claudication
#17
Amy Elizabeth Harwood, Jordan Green, Thomas Cayton, Ali Raza, Tom Wallace, Daniel Carradice, Ian Clifford Chetter, George Edward Smith
BACKGROUND: Intermittent claudication is the most common symptom of peripheral arterial disease. Previous research has suggested that extracorporeal shockwave therapy (ESWT) may induce angiogenesis in treated tissue. The objective of this feasibility pilot trial was to assess the safety, tolerability, and efficacy of ESWT as a novel treatment. METHODS: Patients with unilateral claudication were randomized to receive ESWT or sham treatment to the calf muscle three times per week for 3 weeks...
September 21, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28942739/the-predictive-value-of-symptoms-for-anxiety-in-hospice-inpatients-with-advanced-cancer
#18
Danielle Zweers, Everlien de Graaf, Alexander de Graeff, Rebecca K Stellato, Petronella O Witteveen, Saskia C C M Teunissen
OBJECTIVE: Insight into symptoms as predictors for anxiety may help to foster early identification of anxiety and to ameliorate anxiety management. The aim of this study was to determine which frequently occurring symptoms are predictors for anxiety in advanced cancer patients recently admitted to a hospice. METHOD: Symptom burden was measured in patients admitted to a hospice who died ≤3 month after admission using the Utrecht Symptom Diary. This is a Dutch-translated and adapted version of the Edmonton Symptom Assessment System to self-assess the 11 most prevalent symptoms and overall well-being on a 0-10 numerical rating scale...
September 25, 2017: Palliative & Supportive Care
https://www.readbyqxmd.com/read/28942715/pharmacokinetics-and-safety-of-fentanyl-sublingual-spray-and-fentanyl-citrate-intravenous-a-multiple-ascending-dose-study-in-opioid-na%C3%A3-ve-healthy-volunteers
#19
Richard L Rauck, D Alexander Oh, Neil Singla, Christian Koch, Neha Parikh, Srinivas Nalamachu, Daniel Wilson, Jin Yu, Santosh Vetticaden
OBJECTIVE: Fentanyl sublingual spray, with its rapid onset for pain relief, may be efficacious in the management of acute or post-operative pain. Because patients in these settings may be opioid-naïve, the study was conducted to determine the safety, tolerability, and pharmacokinetics of multiple dose administration of fentanyl sublingual spray in an opioid-naïve population. METHODS: Fentanyl sublingual spray (100 mcg, 200 mcg, and 400 mcg) and fentanyl citrate intravenous (IV; 50 mcg) were administered every 0...
September 23, 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/28942705/clinical-outcome-after-plaster-cast-fixation-for-10%C3%A2-days-versus-1%C3%A2-month-in-reduced-distal-radius-fractures-a-prospective-randomized-study
#20
A Christersson, S Larsson, B Sandén
INTRODUCTION: This study aimed to evaluate clinical results after plaster cast fixation for 10 days versus 1 month of moderately displaced and reduced distal radius fractures. MATERIAL AND METHODS: In a prospective randomized study, 109 patients with moderately displaced and conservatively treated distal radius fractures (age ≥50 years) were randomized 10 days after reduction to either removal of the plaster cast and immediate mobilization (active group) or to continued plaster cast fixation for another 3 weeks (control group)...
September 1, 2017: Scandinavian Journal of Surgery: SJS
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