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Aedes aegypti

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https://www.readbyqxmd.com/read/29228197/efficacy-of-13-commercial-household-aerosol-insecticides-against-aedes-aegypti-diptera-culicidae-from-morelos-mexico
#1
Pablo A Kuri-Morales, Fabián Correa-Morales, Cassandra González-Acosta, Miguel Moreno-Garcia, Eduardo Dávalos-Becerril, José Ismael Benitez-Alva, Jorge Peralta-Rodriguez, Victor Salazar-Bueyes, Jesús F González-Roldán
In Mexico, Aedes aegypti (L.) (Diptera: Culicidae) is the primary vector of Dengue, Zika, and Chikungunya viruses. Control programs include community participation using personal protection such as household aerosol insecticides. In both, urban or rural areas, the use of aerosol insecticides is a common practice to avoiding mosquito biting. Thus, information on the efficacy of commercial products must be available. This study reports the efficacy of 13 household aerosol insecticides against Ae. aegypti from an endemic dengue area in Mexico...
December 8, 2017: Journal of Medical Entomology
https://www.readbyqxmd.com/read/29225429/in-silico-validation-of-d7-salivary-protein-derived-b-and-t-cell-epitopes-of-aedes-aegypti-as-potential-vaccine-to-prevent-transmission-of-flaviviruses-and-togaviruses-to-humans
#2
Sathish Sankar, Mageshbabu Ramamurthy, Balaji Nandagopal, Gopalan Sridharan
Mosquito (Aedes aegyptii) salivary proteins play a crucial role in facilitating viral transmission from vector-to-host due to their role in facilitating the "blood meal" of the vector. Three main proteins, D7, aegyptin and Sialokinin play a role in this process. Using in-silico programs, we identified B- and T-cell epitopes in the mosquito salivary proteins D7 long and short form. T-cell epitopes with high affinity to the most prevalent HLA MHC class-I supertypes among different population groups was chosen...
2017: Bioinformation
https://www.readbyqxmd.com/read/29223796/species-specific-rna-a-to-i-editing-of-mosquito-rdl-modulates-gaba-potency-and-influences-agonistic-potentiating-and-antagonistic-actions-of-ivermectin
#3
Jennina Taylor-Wells, Anish Senan, Isabel Bermudez, Andrew K Jones
The insect GABA receptor, RDL, is the target of several classes of pesticides. The peptide sequences of RDL are generally highly conserved between diverse insects. However, RNA A-to-I editing can effectively alter amino acid residues of RDL in a species specific manner, which can affect the potency of GABA and possibly insecticides. We report here that RNA A-to-I editing alters the gene products of Rdl in three mosquito disease vectors, recoding five amino acid residues in RDL of Aedes aegypti and six residues in RDLs of Anopheles gambiae and Culex pipiens, which is the highest extent of editing in RDL observed to date...
December 6, 2017: Insect Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/29221490/the-first-detected-airline-introductions-of-yellow-fever-mosquitoes-aedes-aegypti-to-europe-at-schiphol-international-airport-the-netherlands
#4
A Ibañez-Justicia, A Gloria-Soria, W den Hartog, M Dik, F Jacobs, A Stroo
BACKGROUND: Air-borne introduction of exotic mosquitoes to Schiphol airport in the Netherlands has been considered plausible based upon findings of mosquitoes in aircraft cabins during 2008, 2010 and 2011. Beginning in 2013, surveillance efforts at Schiphol had focused on promptly detecting accidental introductions at the airport facilities in order to quickly react and avoid temporary proliferation or establishment of mosquito populations, identify the origin of the introductions, and avoid potential transmission of vector-borne diseases...
December 8, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/29217791/full-length-genome-sequence-of-a-chikungunya-virus-isolate-from-the-2017-autochthonous-outbreak-lazio-region-italy
#5
Fabrizio Carletti, Patrizia Marsella, Francesca Colavita, Silvia Meschi, Eleonora Lalle, Licia Bordi, Domenico Di Lallo, Vincenzo Panella, Antonino Di Caro, Emanuele Nicastri, Paola Scognamiglio, Simone Lanini, Francesco Vairo, Maria R Capobianchi, Giuseppe Ippolito, Concetta Castilletti
We report here the genome sequence of a human chikungunya virus isolate from the ongoing autochthonous outbreak in central Italy. The sequence (East-Central-South African lineage, Indian Ocean sublineage), which is similar to recent sequences from Pakistan and India, shows E1 and E2 signatures of strains whose main mosquito vector is Aedes aegypti, although Aedes albopictus is the vector in Italy.
December 7, 2017: Genome Announcements
https://www.readbyqxmd.com/read/29217627/the-gastric-caecum-of-larval-aedes-aegypti-stimulation-of-epithelial-ion-transport-by-5-hydroxytryptamine-and-camp
#6
Natalie M D'Silva, Michael J O'Donnell
We report measurements of ion transport across the gastric caecum of larvae of Aedes aegypti, a vector of yellow fever that inhabits a variety of aquatic habitats ranging from freshwater to brackish water. We provide the first measurements of the effect of 5-hydroxytryptamine (5-HT) on transepithelial potential (TEP), luminal ion concentrations and electrochemical potentials, as well as basolateral membrane potential and H+, Na+ and K+ fluxes. TEP, basolateral membrane potential, and H+, K+, and Na+ fluxes across the gastric caeca declined within 3-6 mins after isolation of the entire midgut from the larva...
December 7, 2017: Journal of Experimental Biology
https://www.readbyqxmd.com/read/29217264/the-immune-strategies-of-mosquito-aedes-aegypti-against-microbial-infection
#7
Yan-Hong Wang, Meng-Meng Chang, Xue-Li Wang, Ai-Hua Zheng, Zhen Zou
Yellow fever mosquito Aedes aegypti transmits many devastating arthropod-borne viruses (arboviruses), such as dengue virus, yellow fever virus, Chikungunya virus, and Zika virus, which cause great concern to human health. Mosquito control is an effective method to block the spread of infectious diseases. Ae. aegypti uses its innate immune system to fight against arboviruses, parasites, and fungi. In this review, we briefly summarize the recent findings in the immune response of Ae. aegypti against arboviral and entomopathogenic infections...
December 4, 2017: Developmental and Comparative Immunology
https://www.readbyqxmd.com/read/29216317/novel-wolbachia-transinfected-aedes-aegypti-mosquitoes-possess-diverse-fitness-and-vector-competence-phenotypes
#8
Johanna E Fraser, Jyotika Taneja De Bruyne, Iñaki Iturbe-Ormaetxe, Justin Stepnell, Rhiannon L Burns, Heather A Flores, Scott L O'Neill
Wolbachia pipientis from Drosophila melanogaster (wMel) is an endosymbiotic bacterium that restricts transmission of human pathogenic flaviviruses and alphaviruses, including dengue, Zika, and chikungunya viruses, when introduced into the mosquito vector Aedes aegypti. To date, wMel-infected Ae. aegypti have been released in field trials in 5 countries to evaluate the effectiveness of this strategy for disease control. Despite the success in establishing wMel-infected mosquitoes in wild populations, and the well-characterized antiviral capabilities of wMel, transinfecting different or additional Wolbachia strains into Ae...
December 7, 2017: PLoS Pathogens
https://www.readbyqxmd.com/read/29216248/effect-of-land-use-changes-on-the-abundance-distribution-and-host-seeking-behavior-of-aedes-arbovirus-vectors-in-oil-palm-dominated-landscapes-southeastern-c%C3%A3-te-d-ivoire
#9
Julien B Z Zahouli, Benjamin G Koudou, Pie Müller, David Malone, Yao Tano, Jürg Utzinger
BACKGROUND: Identifying priority areas for vector control is of considerable public health relevance. Arthropod-borne viruses (arboviruses) spread by Aedes mosquitoes are (re)emerging in many parts of the tropics, partially explained by changes in agricultural land-use. We explored the effects of land-use changes on the abundance, distribution, and host-seeking behavior of Aedes mosquitoes along a gradient of anthropogenic disturbance in oil palm-dominated landscapes in southeastern Côte d'Ivoire...
2017: PloS One
https://www.readbyqxmd.com/read/29211244/dengue-serotype-specific-immune-response-in-aedes-aegypti-and-aedes-albopictus
#10
Chelsea T Smartt, Dongyoung Shin, Barry W Alto
BACKGROUND: Dengue viruses (DENV) are considered one of the most important emerging pathogens and dengue disease is a global health threat. The geographic expansion of dengue viruses has led to co-circulation of all four dengue serotypes making it imperative that new DENV control strategies be devised. OBJECTIVES: Here we characterize dengue serotype-specific innate immune responses in Aedes aegypti and Aedes albopictus using DENV from Puerto Rico (PR). METHODS: Ae...
December 2017: Memórias do Instituto Oswaldo Cruz
https://www.readbyqxmd.com/read/29206076/assessment-of-the-ability-of-v920-recombinant-vesicular-stomatitis-zaire-ebolavirus-vaccine-to-replicate-in-relevant-arthropod-cell-cultures-and-vector-species
#11
Nicholas A Bergren, Megan R Miller, Thomas P Monath, Rebekah C Kading
V920, rVSVΔG-ZEBOV-GP, is a recombinant vesicular stomatitis-Zaire ebolavirus vaccine which has shown an acceptable safety profile and provides a protective immune response against Ebola virus disease (EVD) induced by Zaire ebolavirus in humans. The purpose of this study was to determine whether the V920 vaccine is capable of replicating in arthropod cell cultures of relevant vector species and of replicating in live mosquitoes. While the V920 vaccine replicated well in Vero cells, no replication was observed in Anopheles or Aedes mosquito, Culicoides biting midge, or Lutzomyia sand fly cells, nor in live Culex or Aedes mosquitoes following exposure through intrathoracic inoculation or feeding on a high-titer infectious blood meal...
December 5, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/29205153/an-aedes-aegypti-associated-fungus-increases-susceptibility-to-dengue-virus-by-modulating-gut-trypsin-activity
#12
Yesseinia I Angleró-Rodríguez, Octavio Ac Talyuli, Benjamin J Blumberg, Seokyoung Kang, Celia Demby, Alicia Shields, Jenny Carlson, Natapong Jupatanakul, George Dimopoulos
Transmission of dengue virus (DENV) requires successful completion of the infection cycle in the Aedes aegypti vector, which is initiated in the midgut tissue after ingestion of an infectious blood meal. While certain Ae. aegypti midgut-associated bacteria influence virus infection, little is known about the midgut-associated fungi (mycobiota), and how its members might influence susceptibility to DENV infection. We show that a Talaromyces (Tsp_PR) fungus, isolated from field-caught Ae. aegypti, render the mosquito more permissive to DENV infection...
December 5, 2017: ELife
https://www.readbyqxmd.com/read/29202694/alternative-patterns-of-sex-chromosome-differentiation-in-aedes-aegypti-l
#13
Corey L Campbell, Laura B Dickson, Saul Lozano-Fuentes, Punita Juneja, Francis M Jiggins, William C Black
BACKGROUND: Some populations of West African Aedes aegypti, the dengue and zika vector, are reproductively incompatible; our earlier study showed that divergence and rearrangements of genes on chromosome 1, which bears the sex locus (M), may be involved. We also previously described a proposed cryptic subspecies SenAae (PK10, Senegal) that had many more high inter-sex FST genes on chromosome 1 than did Ae.aegypti aegypti (Aaa, Pai Lom, Thailand). The current work more thoroughly explores the significance of those findings...
December 4, 2017: BMC Genomics
https://www.readbyqxmd.com/read/29202041/global-transcriptome-analysis-of-aedes-aegypti-mosquitoes-in-response-to-zika-virus-infection
#14
Kayvan Etebari, Shivanand Hegde, Miguel A Saldaña, Steven G Widen, Thomas G Wood, Sassan Asgari, Grant L Hughes
Zika virus (ZIKV) of the Flaviviridae family is a recently emerged mosquito-borne virus that has been implicated in the surge of the number of microcephaly instances in South America. The recent rapid spread of the virus led to its declaration as a global health emergency by the World Health Organization. The virus is transmitted mainly by the mosquito Aedes aegypti, which is also the vector of dengue virus; however, little is known about the interactions of the virus with the mosquito vector. In this study, we investigated the transcriptome profiles of whole A...
November 2017: MSphere
https://www.readbyqxmd.com/read/29196275/global-risk-mapping-for-major-diseases-transmitted-by-aedes-aegypti-and-aedes-albopictus
#15
Samson Leta, Tariku Jibat Beyene, Eva M De Clercq, Kebede Amenu, Crawford Revie
OBJECTIVES: The objective of this study was to map the global risk of the major arboviral diseases transmitted by Aedes aegypti and Ae. albopictus by identifying areas where the diseases are reported either through active transmission or travel related outbreaks, as well as areas where the diseases are not currently reported but are nonetheless suitable for the vector. METHODS: This study extracts data from some of the largest contemporary databases relating to five arboviral diseases (Zika, dengue fever, chikungunya, yellow fever and RVF) and pairs these data with the known distribution of their vectors, Ae...
November 28, 2017: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/29193680/larvicidal-and-residual-activity-of-imidazolium-salts-against-aedes-aegypti-diptera-culicidae
#16
Emanuelle Goellner, Ademir Tramontini Schmitt, Júlia Lacerda Couto, Nicolas Drumm Müller, Harry Luiz Pilz Junior, Henri Stephan Schrekker, Carlos Eugenio Silva, Onilda Santos da Silva
BACKGROUND: Aedes aegypti is an important species of mosquito, which can transmit several arboviruses such as Dengue fever, Yellow fever, Chikungunya, and Zika. As these mosquitoes are becoming resistant to most chemical insecticides used in the world, studies with new larvicides should be prioritized. Based on the known biological profile of imidazolium salts (IS), the objective of this study was to evaluate the potential of six IS as larvicides against Ae. aegypti, which was tested against Ae...
November 28, 2017: Pest Management Science
https://www.readbyqxmd.com/read/29193604/first-insights-on-insecticidal-activity-upon-aedes-aegypti-and-partial-biochemical-characterization-of-a-novel-low-molecular-mass-chymotrypsin-trypsin-inhibitor-purified-from-lonchocarpus-sericeus-seeds
#17
Luiz C P Almeida Filho, Pedro M S Tabosa, Denise C Hissa, Ilka M Vasconcelos, Ana F U Carvalho
BACKGROUND: Arboviroses such as dengue, zika and chikungunya represent a serious issue in public health due to the absence of approved vaccine or specific antiviral drugs. One way to prevent these diseases is by combating the vector mosquito, Aedes aegypti (Diptera), which has serine proteases in the midgut. Protease inhibitors are molecules that can block enzyme activity impairing digestion and nutrition that can lead to death. Thus, we purified and characterized a novel chymotrypsin- trypsin inhibitor from Lonchocarpus sericeus (LsCTI) seeds and investigated its effect upon Ae...
November 28, 2017: Pest Management Science
https://www.readbyqxmd.com/read/29191515/mapping-the-spatial-distribution-of-aedes-aegypti-and-aedes-albopictus
#18
Fangyu Ding, Jingying Fu, Dong Jiang, Mengmeng Hao, Gang Lin
Mosquito-borne infectious diseases, such as Rift Valley fever, Dengue, Chikungunya and Zika, have caused mass human death with the transnational expansion fueled by economic globalization. Simulating the distribution of the disease vectors is of great importance in formulating public health planning and disease control strategies. In the present study, we simulated the global distribution of Aedes aegypti and Aedes albopictus at a 5×5km spatial resolution with high-dimensional multidisciplinary datasets and machine learning methods Three relatively popular and robust machine learning models, including support vector machine (SVM), gradient boosting machine (GBM) and random forest (RF), were used...
November 27, 2017: Acta Tropica
https://www.readbyqxmd.com/read/29186579/insecticide-susceptibility-screening-against-culex-and-aedes-diptera-culicidae-mosquitoes-from-the-united-states
#19
Stephanie L Richards, Jo Anne G Balanay, Avian V White, Joe Hope, Kurt Vandock, Brian D Byrd, Michael H Reiskind
Mosquitoes exposed to sublethal doses of insecticides may be selected for resistance to insecticide active ingredients (AIs). Mosquitoes are exposed to AIs through agricultural, public/private mosquito control programs, homeowners, and other sources. Hence, mosquito control programs should routinely measure the resistance/susceptibility status of mosquito populations of public health concern. The objectives here were to determine resistance status for six AIs used in adult mosquito control in the United States to assess how resistance/susceptibility differs between AI, mosquito species (states where > 1 species collected), and between years (some populations sampled for 2 yr)...
November 23, 2017: Journal of Medical Entomology
https://www.readbyqxmd.com/read/29185595/first-evidence-of-zika-virus-venereal-transmission-in-aedes-aegypti-mosquitoes
#20
Jordam William Pereira-Silva, Valdinete Alves do Nascimento, Heliana Christy Matos Belchior, Jéssica Feijó Almeida, Felipe Arley Costa Pessoa, Felipe Gomes Naveca, Claudia María Ríos-Velásquez
BACKGROUND: Aedes aegypti is considered the main Zika virus (ZIKV) vector, and is thought to be responsible for the 2015-2016 outbreak in Brazil. Zika positive Ae. aegypti males collected in the field suggest that vertical and/or venereal transmission of ZIKV may occur. OBJECTIVES: In this study, we aimed to demonstrate that venereal transmission of ZIKV by Ae. aegypti can occur under laboratory conditions. METHODS: Ae. aegypti collected in the city of Manaus, confirmed as negative for Zika, Dengue and Chikungunya virus by reverse transcription real-time polymerase chain reaction (RT-qPCR) (AaM3V- strain), were reared under laboratory conditions and used for the experiments...
November 27, 2017: Memórias do Instituto Oswaldo Cruz
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