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https://www.readbyqxmd.com/read/28730686/high-resolution-manometry-assessment-of-the-lower-esophageal-sphincter-after-contraction-normative-values-and-clinical-correlation
#1
D A Carlson, P J Kahrilas, M Tye, Z Listernick, K Ritter, I Wong, Y Xiao, V Bul, J E Pandolfino
BACKGROUND: The Chicago Classification v3.0 proposed extending the distal contractile integral (DCI) measurement domain to include the lower esophageal sphincter (LES) to enhance the detection of esophageal hypercontractility. However, normative and clinical data for this approach are unreported. We aimed to describe the application of an extended DCI measurement in asymptomatic controls and patients. METHODS: High-resolution manometry (HRM) of 65 asymptomatic controls and 72 patients with normal motility were evaluated retrospectively...
July 21, 2017: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/28721662/ctp-and-dci-we-need-clarification
#2
EDITORIAL
Thomas Mattingly
No abstract text is available yet for this article.
July 18, 2017: Neurocritical Care
https://www.readbyqxmd.com/read/28719016/insecticide-resistance-of-adults-and-nymphs-of-asian-citrus-psyllid-populations-from-apatzing%C3%A3-n-valley-mexico
#3
Saúl Pardo, Ana M Martínez, José I Figueroa, Juan M Chavarrieta, Elisa Viñuela, Ángel Rebollar-Alviter, Mario A Miranda, Javier Valle, Samuel Pineda
BACKGROUND: Control of the Asian citrus psyllid Diaphorina citri Kuwayama, the most important pest of citrus worldwide, is based on the use of insecticides, though unsatisfactory results have recently been reported. In this study, insecticide resistance of D. citri to three insecticides (bifenthrin, malathion, and chlorpyrifos) was examined. RESULTS: Three populations (designed Dci-CParácuaro, Dci-El Junco, and Dci-Antúnez) of both adults and fourth-instar D. citri individuals were collected in 2014 at two and one different times, respectively, from three locations (Crucero de Parácuaro, El Junco, and Antúnez)...
July 18, 2017: Pest Management Science
https://www.readbyqxmd.com/read/28717283/training-pathways-in-oral-and-maxillofacial-surgery-across-the-globe-a-mini-review
#4
REVIEW
Sanjeev Kumar
Due to historical reasons, many different training pathways exist across countries that lead to a degree in oral and maxillofacial surgery. Although it is generally accepted to be a specialty of dentistry, the complex nature of procedures being performed by OMF surgeons today, has necessitated extensive general surgical training. Many countries have thus made dual qualification mandatory, while others have extended training programs in OMFS with integrated medical teaching. In India, frequent contact with foriegn experts, availability of world-class equipment and efforts of individual surgeons has ensured that the full scope of OMFS is practised in select centres of learning...
September 2017: Journal of Maxillofacial and Oral Surgery
https://www.readbyqxmd.com/read/28697545/synthesis-of-reduced-size-gold-nanostars-and-internalization-in-sh-sy5y-cells
#5
Giacomo Dacarro, Piersandro Pallavicini, Serena Maria Bertani, Giuseppe Chirico, Laura D'Alfonso, Andrea Falqui, Nicoletta Marchesi, Alessia Pascale, Laura Sironi, Angelo Taglietti, Efisio Zuddas
The synthesis of large pentatwinned five-branched gold nanostars (GNS) has been modified so to obtain overall dimensions shrunk to 60% and a lower branches aspect ratio, leading to a dramatic blue shift of their two near-infrared (NIR) localized surface plasmon resonances (LSPR) absorptions but still maintaining one LSPR in the biotransparent NIR range. The interactions of polyethylene glycol (PEG) coated large and shrunk GNS with SH-SY5Y cells revealed that the large ones (DCI - diameter of the circumference in which GNS can be inscribed=76nm) are internalized more efficiently than the shrunk ones (DCI=46nm), correlating with a decreased cells surviving fraction...
July 1, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28693424/bacillus-subtilis-iolq-dega-is-a-transcriptional-repressor-of-iolx-encoding-nad-dependent-scyllo-inositol-dehydrogenase
#6
Dong-Min Kang, Christophe Michon, Tetsuro Morinaga, Kosei Tanaka, Shinji Takenaka, Shu Ishikawa, Ken-Ichi Yoshida
BACKGROUND: Bacillus subtilis is able to utilize at least three inositol stereoisomers as carbon sources, myo-, scyllo-, and D-chiro-inositol (MI, SI, and DCI, respectively). NAD(+)-dependent SI dehydrogenase responsible for SI catabolism is encoded by iolX. Even in the absence of functional iolX, the presence of SI or MI in the growth medium was found to induce the transcription of iolX through an unknown mechanism. RESULTS: Immediately upstream of iolX, there is an operon that encodes two genes, yisR and iolQ (formerly known as degA), each of which could encode a transcriptional regulator...
July 11, 2017: BMC Microbiology
https://www.readbyqxmd.com/read/28678112/prosthesis-and-hybrid-strategy-consideration-for-treating-2-level-cervical-disc-degeneration-in-hybrid-surgery
#7
Yang Li, Guy R Fogel, Zhenhua Liao, Rajnesh Tyagi, Weiqiang Liu
STUDY DESIGN: Biomechanical analysis using a validated nonlinear finite element (FE) model. OBJECTIVE: To combine the strategy of two-level hybrid surgery (HS) to explore how prostheses affect cervical biomechanics. SUMMARY OF BACKGROUND DATA: Few FE studies have explored differences in biomechanical behavior between combined and stand-alone structured prostheses with HS. No FE studies have considered whether the prosthesis type and hybrid strategy influence two-level HS...
July 3, 2017: Spine
https://www.readbyqxmd.com/read/28667021/early-prediction-of-delayed-ischemia-and-functional-outcome-in-acute-subarachnoid-hemorrhage-role-of-diffusion-tensor-imaging
#8
Isabel Fragata, Marta Alves, Ana Luísa Papoila, Ana Paiva Nunes, Patrícia Ferreira, Nuno Canto-Moreira, Patrícia Canhão
BACKGROUND AND PURPOSE: Diffusion tensor imaging (DTI) parameters are markers of cerebral lesion in some diseases. In patients with acute subarachnoid hemorrhage (SAH), we investigated whether DTI parameters measured at <72 hours might be associated with delayed cerebral ischemia (DCI) and with poor functional outcome at 3 months (modified Rankin Scale score ≥3). METHODS: DTI was performed in a prospective cohort of 60 patients with nontraumatic SAH at <72 hours...
June 30, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28665071/feasibility-and-safety-of-mild-therapeutic-hypothermia-in-poor-grade-subarachnoid-hemorrhage-prospective-pilot-study
#9
Wookjin Choi, Soon Chan Kwon, Won Joo Lee, Young Cheol Weon, Byungho Choi, Hyeji Lee, Eun Suk Park, Ryeok Ahn
Therapeutic hypothermia (TH) improves the neurological outcome in patients after cardiac arrest and neonatal hypoxic brain injury. We studied the safety and feasibility of mild TH in patients with poor-grade subarachnoid hemorrhage (SAH) after successful treatment. Patients were allocated randomly to either the TH group (34.5°C) or control group after successful clipping or coil embolization. Eleven patients received TH for 48 hours followed by 48 hours of slow rewarming. Vasospasm, delayed cerebral ischemia (DCI), functional outcome, mortality, and safety profiles were compared between groups...
August 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28661267/clinical-evidence-of-efficacy-of-simvastatin-for-aneurysmal-subarachnoid-hemorrhage
#10
Jinghui Lin, Houxian Liu, Jianjun Jiang, Conglin Jia, Bin Zhang, Xiang Gao
Objective The present study was performed to explore the therapeutic potential of simvastatin in subarachnoid hemorrhage (SAH) in the context of the Simvastatin in Aneurysmal Subarachnoid Hemorrhage (STASH) trial. Methods MEDLINE, EMBASE, and the Cochrane Library were searched for all randomized controlled trials (RCTs) investigating the therapeutic effect of simvastatin on aneurysmal SAH. We applied a random-effects model to calculate the data. Results Five RCTs involving 951 patients met the eligibility criteria...
January 1, 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/28642705/polycystic-ovary-syndrome-insights-into-the-therapeutic-approach-with-inositols
#11
REVIEW
Maria A Sortino, Salvatore Salomone, Michele O Carruba, Filippo Drago
Polycystic ovary syndrome (PCOS) is characterized by hormonal abnormalities that cause menstrual irregularity and reduce ovulation rate and fertility, associated to insulin resistance. Myo-inositol (cis-1,2,3,5-trans-4,6-cyclohexanehexol, MI) and D-chiro-inositol (cis-1,2,4-trans-3,5,6-cyclohexanehexol, DCI) represent promising treatments for PCOS, having shown some therapeutic benefits without substantial side effects. Because the use of inositols for treating PCOS is widespread, a deep understanding of this treatment option is needed, both in terms of potential mechanisms and efficacy...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28641324/treatment-preferences-for-decompression-illness-amongst-singapore-dive-physicians
#12
Valerie Huali Tan, Kenneth Chin, Aravin Kumar, Jeremiah Chng, Chai Rick Soh Rick Soh
INTRODUCTION: Owing to the scarcity of randomized controlled trials to guide treatment for decompression illness (DCI), there are many unanswered questions about its management. Apart from reviews and expert opinion, surveys that report practice patterns provide information about useful management strategies. Hence, this study aimed to identify current treatment preferences for DCI amongst diving physicians in Singapore. METHODS: An anonymous web-based questionnaire was sent to known diving physicians in Singapore...
June 2017: Diving and Hyperbaric Medicine: the Journal of the South Pacific Underwater Medicine Society
https://www.readbyqxmd.com/read/28639001/sanguinate%C3%A2-pegylated-carboxyhemoglobin-bovine-improves-cerebral-blood-flow-to-vulnerable-brain-regions-at-risk-of-delayed-cerebral-ischemia-after-subarachnoid-hemorrhage
#13
Rajat Dhar, Hemant Misra, Michael N Diringer
BACKGROUND: Delayed cerebral ischemia (DCI) after subarachnoid hemorrhage (SAH) has been linked to focal reductions in cerebral blood flow (CBF) and microvascular impairments in oxygen delivery. Effective therapies that restore flow and oxygen transport to vulnerable brain regions are currently lacking. SANGUINATE is a dual-action carbon monoxide-releasing and hemoglobin-based oxygen transfer agent with efficacy in animal models of focal brain ischemia and tolerability in patients with sickle cell disease...
June 21, 2017: Neurocritical Care
https://www.readbyqxmd.com/read/28608885/facile-synthesis-of-an-ultra-stable-metal-organic-framework-with-excellent-acid-and-base-resistance
#14
Nian Zhao, Ping Li, Xin Mu, Chuanfang Liu, Fuxing Sun, Guangshan Zhu
A novel ultra-stable metal-organic framework, MCIF-1, [Cu2(DCI)2](MeCN), based on dicyanoimidazole and Cu(i), has been synthesized at room temperature successfully. MCIF-1 shows excellent water stability and can retain crystallinity after soaking in water for about one week. In addition, MCIF-1 also shows exceptional resistance under both acidic and basic conditions within a large pH range from 0 to 13.5. What is more, after modifying the synthesis procedure slightly, we can produce this material in a large scale during a very short time...
June 13, 2017: Faraday Discussions
https://www.readbyqxmd.com/read/28600999/how-do-risk-factors-affect-bereavement-outcomes-in-later-life-an-exploration-of-the-mediating-role-of-dual-process-coping
#15
Suqin Tang, Amy Y M Chow
This study is an exploratory study that aims to examine the mediating role of dual process coping in the relationship between risk factors and bereavement outcomes. A total of 178 Hong Kong Chinese bereaved older adults reported their bereavement-related information, dual process coping (Dual Coping Inventory, DCI), complicated grief (Inventory of Complicated Grief; ICG), depression (Geriatric Depression Scale, GDS) and loneliness (De Jong Gierveld Loneliness Scale, DJG) in face-to-face structured interviews...
June 2, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28599907/association-of-plasminogen-activator-inhibitor-1-serpine1-gene-polymorphisms-and-aneurysmal-subarachnoid-hemorrhage
#16
Philipp Hendrix, Paul M Foreman, Mark R Harrigan, Winfield S Fisher, Nilesh A Vyas, Robert H Lipsky, Minkuan Lin, Beverly C Walters, R Shane Tubbs, Mohammadali M Shoja, Jean-Francois Pittet, Mali Mathru, Christoph J Griessenauer
OBJECTIVE: Genetic variations of the SERPINE1 gene, which encodes plasminogen activator inhibitor 1 (PAI-1), correlate with serum levels of its product and are associated with thrombophilia and coronary atherosclerosis. Various SERPINE1 gene polymorphisms have been identified. Only the functional 5G/4G polymorphism, however, has been assessed in the context of aneurysmal subarachnoid hemorrhage (aSAH). Here, we assessed associations of 6 SERPINE1 polymorphisms with the clinical sequelae of aSAH...
June 6, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28589298/changes-in-esophageal-motility-after-acupuncture
#17
Felipe M Vieira, Fernando A M Herbella, Daniel H Habib, Marco G Patti
BACKGROUND: Chinese medicine is widely used in the East with good results for the treatment of many diseases. Acupuncture has been increasingly used and recognized as a complementary medical treatment. Some studies on gastrointestinal motility are available; however, acupuncture effect on esophageal motility is still elusive due to the lack of studies with adequate methodology. This study aims to evaluate acupuncture effect on esophageal motility. METHODS: We studied 16 (50% females, mean age 26 years) volunteers...
August 2017: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/28585270/intra-and-interrater-reliability-of-the-chicago-classification-of-achalasia-subtypes-in-pediatric-high-resolution-esophageal-manometry-hrm-recordings
#18
M M J Singendonk, R Rosen, J Oors, N Rommel, M P van Wijk, M A Benninga, S Nurko, T I Omari
BACKGROUND: Subtyping achalasia by high-resolution manometry (HRM) is clinically relevant as response to therapy and prognosis have shown to vary accordingly. The aim of this study was to assess inter- and intrarater reliability of diagnosing achalasia and achalasia subtyping in children using the Chicago Classification (CC) V3.0. METHODS: Six observers analyzed 40 pediatric HRM recordings (22 achalasia and 18 non-achalasia) twice by using dedicated analysis software (ManoView 3...
June 6, 2017: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/28582545/stereotactic-catheter-ventriculocisternostomy-for-clearance-of-subarachnoid-hemorrhage-in-patients-with-coiled-aneurysms
#19
Roland Roelz, Christian Scheiwe, Horst Urbach, Volker A Coenen, Peter Reinacher
BACKGROUND: Cerebral vasospasm leading to delayed cerebral infarction (DCI) is a central source of poor outcome in patients with aneurysmal subarachnoid hemorrhage (aSAH). Current treatments of cerebral vasospasm are insufficient. Cisternal blood clearance is a promising treatment option. However, a generally applicable, safe, and effective method to access the cisterns of the brain is lacking. OBJECTIVE: To report on stereotactic catheter ventriculocisternostomy (STX-VCS) as a method to access the cisterns of the brain for clearance of subarachnoid hemorrhage in patients with aSAH and coiled aneurysms...
June 3, 2017: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/28574309/early-low-cerebral-blood-flow-and-high-cerebral-lactate-prediction-of-delayed-cerebral-ischemia-in-subarachnoid-hemorrhage
#20
Elham Rostami, Henrik Engquist, Timothy Howells, Ulf Johnson, Elisabeth Ronne-Engström, Pelle Nilsson, Lars Hillered, Anders Lewén, Per Enblad
OBJECTIVE Delayed cerebral ischemia (DCI) following subarachnoid hemorrhage (SAH) is one of the major contributors to poor outcome. It is crucial to be able to detect early signs of DCI to prevent its occurrence. The objective of this study was to determine if low cerebral blood flow (CBF) measurements and pathological microdialysis parameters measured at the bedside can be observed early in patients with SAH who later developed DCI. METHODS The authors included 30 patients with severe SAH. The CBF measurements were performed at Day 0-3 after disease onset, using bedside xenon-CT...
June 2, 2017: Journal of Neurosurgery
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