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Extracorporeal life support

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https://www.readbyqxmd.com/read/28325778/extracorporeal-life-support-as-a-bridge-to-lung-transplantation-a-single-center-experience-with-an-emphasis-on-health-related-quality-of-life
#1
Annemieke Oude Lansink-Hartgring, Wim van der Bij, Erik A Verschuuren, Michiel E Erasmus, Adrianus J de Vries, Karin M Vermeulen, Walter M van den Bergh
BACKGROUND: Extracorporeal life support (ECLS) as a bridge to lung transplantation is increasingly used, but information on long-term outcome is scarce. We aim to summarize our experience with an emphasis on health-related quality of life. Secondary outcomes include ICU and hospital stay and pre- and post-transplant mortality. METHODS: A retrospective cohort study of all adult subjects receiving ECLS as a bridge to lung transplantation from 2010 to 2014 was reviewed and compared with all adult subjects who underwent bilateral lung transplantation in the same period...
March 21, 2017: Respiratory Care
https://www.readbyqxmd.com/read/28301052/decreased-blood-product-usage-during-extracorporeal-life-support-with-reduced-circuit-volumes
#2
Samuel D Addison, Marcia L Buck, Gary Y Fang, James J Gangemi, David A Kaufman
BACKGROUND: Activation and consumption of platelets (PLT) and clotting factors along with hemolysis occurs when blood contacts the extracorporeal life support (ECLS) circuit and its components. STUDY DESIGN AND METHODS: The objective was to examine the effects of reducing ECLS circuit volume by decreasing tubing length and changing components on blood product usage in neonatal and pediatric patients. Blood product administration was analyzed in 40 consecutive patients who required ECLS for respiratory or cardiac failure before (PRE) and after (POST) changes in circuit design and components...
March 16, 2017: Transfusion
https://www.readbyqxmd.com/read/28296181/-white-out-after-lung-transplantation-a-multicentre-cohort-description-of-late-acute-graft-failure
#3
Stijn E Verleden, Jens Gottlieb, Adriana Dubbeldam, Geert M Verleden, Hendrik Suhling, Tobias Welte, Robin Vos, Mark Greer
Graft failure represents a leading cause of mortality following organ transplantation. Acute late-onset graft failure has not been widely reported. This paper describes the demographics, CT imaging pathology findings and treatment of patients presenting with the latter. A retrospective review of lung transplant recipients at 2 large-volume centres was performed. Acute late-onset graft failure was defined as sudden onset of bilateral infiltrates with an oxygenation index <200 without identifiable cause or concurrent extra-pulmonary organ failure...
March 12, 2017: American Journal of Transplantation
https://www.readbyqxmd.com/read/28291121/extracorporeal-life-support-for-electrical-storm-or-for-cardiogenic-shock-with-ventricular-arrhythmia
#4
Corstiaan A den Uil
No abstract text is available yet for this article.
April 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28291093/racial-and-ethnic-variation-in-pediatric-cardiac-extracorporeal-life-support-survival
#5
Titus Chan, Jane Di Gennaro, Reid W D Farris, Monique Radman, David Michael McMullan
OBJECTIVES: Previous studies have suggested an association between nonwhite race and poor outcomes in small subsets of cardiac surgery patients who require extracorporeal life support. This study aims to examine the association of race/ethnicity with mortality in pediatric patients who receive extracorporeal life support for cardiac support. DESIGN: Retrospective analysis of registry data. SETTING: Prospectively collected multi-institutional registry data...
April 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28275618/extracorporeal-life-support-for-refractory-ventricular-tachycardia
#6
REVIEW
Sujatha P Bhandary, Nicholas Joseph, James P Hofmann, Theodosios Saranteas, Thomas J Papadimos
Extracorporeal life support (ECLS) is a very effective bridging therapy in patients with refractory ventricular tachycardia (VT) associated with cardiogenic shock. A moribund patient in extremis, is not amenable to optimization by standard ACC/AHA guidelines. New approaches and novel salvage techniques are necessary to improve outcomes in patients with refractory clinical settings such as malignant ventricular arrhythmias, cardiac arrest, cardiogenic shock and/or pulmonary failure until further management options are explored...
February 2017: Annals of Translational Medicine
https://www.readbyqxmd.com/read/28275617/extracorporeal-cardiopulmonary-resuscitation
#7
REVIEW
Nicholson Yam, David Michael McMullan
Extracorporeal life support (ECLS) is used for patients in isolated or combined cardiopulmonary failures. The use of ECLS to rescue patients with cardiac arrest that is refractory to conventional cardiopulmonary resuscitation has been shown to improve survival in many patient populations. Increasing recognition of the survival benefit associated with extracorporeal cardiopulmonary resuscitation (ECPR) has led to increased use of ECPR during the past decade. This review provides an overview of ECPR utilization; population-based clinical outcomes, resource utilization and costs associated this advanced form of life support therapy...
February 2017: Annals of Translational Medicine
https://www.readbyqxmd.com/read/28275615/cannulation-techniques-for-extracorporeal-life-support
#8
REVIEW
Evgeny Pavlushkov, Marius Berman, Kamen Valchanov
The article reviews cannulation strategy for different modes of extracorporeal life support. Technical aspects, pitfalls and complications are discussed for central and peripheral extracorporeal membrane oxygenation (VA, VV, VAV, VVA), biventricular assist device support and extracorporeal CO2 removal.
February 2017: Annals of Translational Medicine
https://www.readbyqxmd.com/read/28275614/considerations-for-analgosedation-and-antithrombotic-management-during-extracorporeal-life-support
#9
REVIEW
Pamela K Burcham, Alan J Rozycki, Erik E Abel
Despite the immense growth in extracorporeal life support (ECLS) technology and experience, opportunity remains to better characterize the pharmacotherapeutic considerations during ECLS. Analgosedation can be particularly challenging in the ECLS population due to in drug-circuit interactions that may lead to decreased systemic concentrations and pharmacodynamic effect. ECLS also requires the use of antithrombotic agents to mitigate the prothrombotic state created by the artificial surface in the ECLS circuit...
February 2017: Annals of Translational Medicine
https://www.readbyqxmd.com/read/28275613/development-of-a-new-interfacility-extracorporeal-membrane-oxygenation-transport-program-for-pediatric-lung-transplantation-evaluation
#10
REVIEW
W Joshua Frazier, Edward G Shepherd, Samantha W Gee
Pediatric lung transplantation is a life-saving intervention for children with irreversible end-stage lung disease. Access to transplant can be limited by geographic isolation from a center or the presence of comorbidities affecting transplant eligibility. Extracorporeal membrane oxygenation (ECMO)-supported patients are an uncommon but historically high-risk cohort of patients considered for lung transplant. We report the development of a service at our center to provide transport services to our hospital for patients unable to wean from ECMO support at their local institution for the purpose of evaluation for lung transplantation by our program...
February 2017: Annals of Translational Medicine
https://www.readbyqxmd.com/read/28275612/initiation-and-management-of-adult-veno-arterial-extracorporeal-life-support
#11
REVIEW
Ahmet Kilic, Bassam N Shukrallah, Arman Kilic, Bryan A Whitson
Extracorporeal life support (ECLS) for patients suffering from acute cardiopulmonary collapse is the penultimate therapy to provide hemodynamic stability. Although it can be a life sustaining as well as life-saving therapy, there are important factors that contribute to its success. In this review, we will describe the indications, management, pitfalls and limitations of ECLS.
February 2017: Annals of Translational Medicine
https://www.readbyqxmd.com/read/28271557/early-cardiac-catheterization-leads-to-shortened-pediatric-extracorporeal-membrane-oxygenation-run-duration
#12
Christopher R Burke, Titus Chan, Agustin E Rubio, David M McMullan
OBJECTIVE: Cardiac catheterization in patients receiving extracorporeal life support (ECLS) has previously been shown to be safe and, in many cases, therapeutic. However, the influence of cardiac catheterization on clinical outcomes in this patient population has not been clearly defined. METHODS: A single institution, retrospective review of all pediatric cardiac ECLS patients who underwent cardiac catheterization between January 2006 and September 2015 was performed...
March 8, 2017: Journal of Interventional Cardiology
https://www.readbyqxmd.com/read/28264702/duration-of-veno-arterial-extracorporeal-life-support-va-ecmo-and-outcome-an-analysis-of-the-extracorporeal-life-support-organization-elso-registry
#13
Myles Smith, Alexander Vukomanovic, Daniel Brodie, Ravi Thiagarajan, Peter Rycus, Hergen Buscher
BACKGROUND: Veno-arterial extracorporeal membrane oxygenation (VA ECMO) is an effective rescue therapy for severe cardiorespiratory failure, but morbidity and mortality are high. We hypothesised that survival decreases with longer VA ECMO treatment. We examined the Extracorporeal Life Support Organization (ELSO) registry for a relationship between VA ECMO duration and in-hospital mortality, and covariates including indication for support. METHODS: All VA runs from the ELSO database from 2002 to 2012 were extracted...
March 6, 2017: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/28263789/pediatric-extracorporeal-cardiopulmonary-resuscitation-during-nights-and-weekends
#14
Christopher R Burke, Titus Chan, Thomas V Brogan, D Michael McMullan
AIM: Extracorporeal cardiopulmonary resuscitation (ECPR) is a lifesaving rescue therapy for patients with refractory cardiac arrest. Previous studies suggest that maintaining a 24/7 in-house surgical team may reduce ECPR initiation time and improve survival in adult patients. However, an association between cardiac arrest occurring during off-hours and ECPR outcome has not been established in children. METHODS: This is a single institution, retrospective review of all pediatric patients who received ECPR from December 2008 to August 2015...
March 2, 2017: Resuscitation
https://www.readbyqxmd.com/read/28252534/extracorporeal-membrane-oxygenation-for-adult-community-acquired-pneumonia-outcomes-and-predictors-of-mortality
#15
Kollengode Ramanathan, Chuen Seng Tan, Peter Rycus, Graeme Maclaren
OBJECTIVES: Extracorporeal membrane oxygenation is a rescue therapy used to support severe cardiorespiratory failure. Data on outcomes from severe community-acquired pneumonia in adults receiving rescue extracorporeal membrane oxygenation are mainly confined to single-center experiences or specific pathogens. We examined data from the Extracorporeal Life Support Organisation registry to identify risk factors for poor outcomes in adult patients with community-acquired pneumonia. DESIGN: Retrospective data analysis...
March 1, 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28251137/extracorporeal-life-support-during-cardiac-arrest-and-cardiogenic-shock-how-good-is-the-evidence-really
#16
COMMENT
Roland Prondzinsky, Karl Werdan
No abstract text is available yet for this article.
February 2017: Annals of Translational Medicine
https://www.readbyqxmd.com/read/28240641/transcatheter-mitral-valve-replacement-with-a-novel-self-expandable-prosthesis-single-institutional-experience-procedural-outcomes-and-follow-up
#17
Gian Paolo Ussia, Valeria Cammalleri, Jawahar L Mehta, Kunal Sarkar, Saverio Muscoli, Pasquale de Vico, Giovanni Ruvolo, Francesco Romeo
AIMS: We report our experience with the CardiAQ prosthetic valve using both transapical and transseptal access. Aim of our study was proving the feasibility, safety and effectiveness of a novel transcatheter mitral valve bioprosthesis. METHODS: Four patients with severe mitral regurgitation, not eligible for mitral valve surgery, were treated with the CardiAQ valve. The procedures were performed under general anaesthesia, fluoroscopic and transesophageal echocardiographic guidance...
February 24, 2017: Journal of Cardiovascular Medicine
https://www.readbyqxmd.com/read/28236098/use-of-extracorporeal-membrane-oxygenation-in-complicated-transcatheter-aortic-valve-replacement
#18
Kyokun Uehara, Kenji Minakata, Naritatsu Saito, Masao Imai, Hiroki Daijo, Taro Nakatsu, Kazuhisa Sakamoto, Kazuhiro Yamazaki, Takeshi Kimura, Ryuzo Sakata
OBJECTIVES: Although transcatheter aortic valve replacement (TAVR) is an excellent alternative procedure for high-risk patients with severe symptomatic aortic stenosis, it is often associated with life-threatening complications. We report on the emergency or elective use of veno-arterial extracorporeal membrane oxygenation (ECMO) to manage these complications. METHODS: Between December 2013 and February 2016, 46 patients underwent TAVR at our institution. Of these, 4 patients required emergency ECMO support and another 3 patients were electively placed on ECMO support at the start of the procedure...
February 24, 2017: General Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28235962/critical-illness-associated-cerebral-microbleeds
#19
Evgenia M Fanou, Jonathan M Coutinho, Patrick Shannon, Tim-Rasmus Kiehl, Marcel M Levi, M Elizabeth Wilcox, Richard I Aviv, Daniel M Mandell
- BACKGROUND AND PURPOSE: Cerebral microbleeds (petechial hemorrhages) are a well-known consequence of cerebral amyloid angiopathy and chronic hypertension among other causes. We report 12 patients with a clinically and radiologically distinct microbleed phenomenon in the cerebral white matter. METHODS: These patients were assessed at the University Health Network (Toronto, Canada) between 2004 and 2014. RESULTS: Median age was 40 years (range, 27-63 years), and 7 out of 12 patients were women...
February 24, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28229199/-coronary-artery-disease-interventional-and-operative-therapeutic-options-after-cardiac-arrest
#20
M Behnes, K Mashayekhi, M Borggrefe, I Akin
Coronary artery disease (CAD) represents a common structural cause for developing cardiac arrest in older patients, whereas in young adults cardiac arrest is more often caused by cardiomyopathies and cardiac channelopathies. A structural heart disease is known in almost 50% of patients prior to cardiac arrest. The present review outlines current interventional and operative therapeutic options for patients surviving cardiac arrest. The focus is on associations between epidemiological data on the incidence of malignant arrhythmias causing cardiac arrest depending on the presence or absence of CAD...
February 22, 2017: Herz
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