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https://www.readbyqxmd.com/read/28339791/bridg-a-domain-information-model-for-translational-and-clinical-protocol-driven-research
#1
Lauren B Becnel, Smita Hastak, Wendy Ver Hoef, Robert P Milius, MaryAnn Slack, Diane Wold, Michael L Glickman, Boris Brodsky, Charles Jaffe, Rebecca Kush, Edward Helton
Background: It is critical to integrate and analyze data from biological, translational, and clinical studies with data from health systems; however, electronic artifacts are stored in thousands of disparate systems that are often unable to readily exchange data. Objective: To facilitate meaningful data exchange, a model that presents a common understanding of biomedical research concepts and their relationships with health care semantics is required. The Biomedical Research Integrated Domain Group (BRIDG) domain information model fulfills this need...
February 26, 2017: Journal of the American Medical Informatics Association: JAMIA
https://www.readbyqxmd.com/read/28339747/deep-learning-for-pharmacovigilance-recurrent-neural-network-architectures-for-labeling-adverse-drug-reactions-in-twitter-posts
#2
Anne Cocos, Alexander G Fiks, Aaron J Masino
Objective: Social media is an important pharmacovigilance data source for adverse drug reaction (ADR) identification. Human review of social media data is infeasible due to data quantity, thus natural language processing techniques are necessary. Social media includes informal vocabulary and irregular grammar, which challenge natural language processing methods. Our objective is to develop a scalable, deep-learning approach that exceeds state-of-the-art ADR detection performance in social media...
February 22, 2017: Journal of the American Medical Informatics Association: JAMIA
https://www.readbyqxmd.com/read/28336341/visuospatial-information-processing-load-and-the-ratio-between-parietal-cue-and-target-p3-amplitudes-in-the-attentional-network-test
#3
Dimitri M Abramov, Monique Pontes, Adailton T Pontes, Carlos A Mourao-Junior, Juliana Vieira, Carla Quero Cunha, Tiago Tamborino, Paulo R Galhanone, Leonardo C deAzevedo, Vladimir V Lazarev
In ERP studies of cognitive processes during attentional tasks, the cue signals containing information about the target can increase the amplitude of the parietal cue P3 in relation to the 'neutral' temporal cue, and reduce the subsequent target P3 when this information is valid, i.e. corresponds to the target's attributes. The present study compared the cue-to-target P3 ratios in neutral and visuospatial cueing, in order to estimate the contribution of valid visuospatial information from the cue to target stages of the task performance, in terms of cognitive load...
March 20, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28330523/public-health-and-disasters-an-emerging-translational-and-implementation-science-not-lessons-learned
#4
Kristi L Koenig, Carl H Schultz, Miryha Gould Runnerstrom, Oladele A Ogunseitan
Disaster Medicine is a relatively new multidisciplinary field of science with clear public health implications as it focuses on improving outcomes for populations rather than for individual patients. As with any other scientific discipline, the goal of public health and disaster research is to create new knowledge and transfer evidence-based data to improve public health. The phrase "lessons learned" has crept into the disaster lexicon but must be permanently erased as it has no place in the scientific method...
March 23, 2017: Disaster Medicine and Public Health Preparedness
https://www.readbyqxmd.com/read/28329176/does-rare-vocabulary-use-distinguish-giftedness-from-typical-development-a-study-of-school-age-african-american-narrators
#5
Monique T Mills, Jamie Mahurin-Smith, Sara C Steele
Purpose: The purpose of this study was to examine rare vocabulary produced in the spoken narratives of school-age African American children. Method: Forty-three children from general and gifted classrooms produced 2 narratives: a personal story and a fictional story that was based on the wordless book Frog, Where Are You? (Mayer, 1969). The Wordlist for Expressive Rare Vocabulary Evaluation (Mahurin-Smith, DeThorne, & Petrill, 2015) was used to tally number and type of uncommon words produced in these narratives...
March 22, 2017: American Journal of Speech-language Pathology
https://www.readbyqxmd.com/read/28324862/heterogeneity-in-predictive-power-of-early-childhood-nutritional-indicators-for-mid-childhood-outcomes-evidence-from-vietnam
#6
Le Thuc Duc, Jere R Behrman
We utilize longitudinal data on nearly 1800 children in Vietnam to study the predictive power of alternative measures of early childhood undernutrition for outcomes at age eight years: weight-for-age (WAZ8), height-for-age (HAZ8), and education (reading, math and receptive vocabulary). We apply two-stage procedures to derive unpredicted weight gain and height growth in the first year of life. Our estimates show that a standard deviation (SD) increase in birth weight is associated with an increase of 0.14 (standard error [SE]: 0...
March 11, 2017: Economics and Human Biology
https://www.readbyqxmd.com/read/28323454/interaction-behaviors-of-bilingual-parents-with-their-young-children-with-autism-spectrum-disorder
#7
Kristelle Hudry, Lisa Rumney, Nicole Pitt, Josephine Barbaro, Giacomo Vivanti
Given concerns that bilingual exposure might confuse children with disabilities-including autism spectrum disorder (ASD)-bilingual parents may restrict exposure to one language, often the community-dominant language. We investigated a potential consequence of this decision; the possibility that non-native language use might influence parental communicative behaviors during interaction with the child. We recruited 39 parent-child dyads, each with a young child with ASD (mostly boys) and parent/carer (mostly mothers)...
March 21, 2017: Journal of Clinical Child and Adolescent Psychology
https://www.readbyqxmd.com/read/28320317/navigo-interactive-tool-for-visualization-and-functional-similarity-and-coherence-analysis-with-gene-ontology
#8
Qing Wei, Ishita K Khan, Ziyun Ding, Satwica Yerneni, Daisuke Kihara
BACKGROUND: The number of genomics and proteomics experiments is growing rapidly, producing an ever-increasing amount of data that are awaiting functional interpretation. A number of function prediction algorithms were developed and improved to enable fast and automatic function annotation. With the well-defined structure and manual curation, Gene Ontology (GO) is the most frequently used vocabulary for representing gene functions. To understand relationship and similarity between GO annotations of genes, it is important to have a convenient pipeline that quantifies and visualizes the GO function analyses in a systematic fashion...
March 20, 2017: BMC Bioinformatics
https://www.readbyqxmd.com/read/28318415/is-the-hebb-repetition-task-a-reliable-measure-of-individual-differences-in-sequence-learning
#9
Louisa Bogaerts, Noam Siegelman, Tali Ben-Porat, Ram Frost
The Hebb repetition task, an operationalization of long-term sequence learning through repetition, is the focus of renewed interest, as it is taken to provide a laboratory analogue for naturalistic vocabulary acquisition. Indeed, recent studies have consistently related performance in the Hebb repetition task with a range of linguistic (dis)abilities. However, in spite of the growing interest in the Hebb repetition effect as a theoretical construct, no previous research has ever tested whether the task used to assess Hebb learning offers a stable and reliable measure of individual performance in sequence learning...
March 20, 2017: Quarterly Journal of Experimental Psychology: QJEP
https://www.readbyqxmd.com/read/28318186/cross-cultural-adaptation-of-the-transition-readiness-assessment-questionnaire-to-argentinian-spanish
#10
Carmen L De Cunto, Alfredo Eymann, María de Los Ángeles Britos, Florencia González, Mariana Roizen, María de Las Mercedes Rodríguez Celin, Enrique Soriano Guppy
In Argentina, there was not an adapted and validated instrument to evaluate readiness for the transition to adult health care. The purpose of this study was to describe the process of cross-cultural adaptation of the Transition Readiness Assessment Questionnaire 5.0 to Argentinian Spanish. The authors of the instrument were contacted to this effect. Stage 1: two translators performed the translation to Spanish. Stage 2: based on these two versions, version 1 was agreed upon. Stage 3: two back-translations were performed...
April 1, 2017: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/28315489/effect-of-angiotensin-2-receptor-blockers-on-chronic-obstructive-lung-disease-mortality-a-retrospective-cohort-study
#11
Pilar Paulin, Joaquin Maritano Furcada, Catalina M Ungaro, Gisela Bendelman, Gabriel D Waisman, Matias H Castro, Diego H Giunta, Bruno L Ferreyro
INTRODUCTION: Chronic Obstructive Pulmonary Disease (COPD) is the fifth cause of mortality worldwide. Systemic inflammation is a crucial element in its physiopathology. As Renin-Angiotensin System is one of the main components of this inflammatory neurohumoral cascade, Angiotensin Receptor Blockers (ARBs) might have an effect on mortality in COPD patients. GOAL: To evaluate the association between ARBs treatment and mortality in COPD patients. METHODS: Retrospective cohort of patients with diagnosis of COPD from 2003 to 2013...
March 14, 2017: Pulmonary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/28302555/development-of-bioinformatics-infrastructure-for-genomics-research-in-h3africa
#12
Nicola J Mulder, Ezekiel Adebiyi, Marion Adebiyi, Seun Adeyemi, Azza Ahmed, Rehab Ahmed, Bola Akanle, Mohamed Alibi, Don L Armstrong, Shaun Aron, Efejiro Ashano, Shakuntala Baichoo, Alia Benkahla, David K Brown, Emile R Chimusa, Faisal M Fadlelmola, Dare Falola, Segun Fatumo, Kais Ghedira, Amel Ghouila, Scott Hazelhurst, Iunu Isewon, Segun Jung, Samar Kamal Kassim, Jonathan K Kayondo, Mamana Mbiyavanga, Ayton Meintjes, Somia Mohammed, Abayomi Mosaku, Ahmed Moussa, Mustafa Muhammd, Zahra Mungloo-Dilmohamud, Oyekanmi Nashiru, Trust Odia, Adaobi Okafor, Olaleye Oladipo, Victor Osamor, Jellili Oyelade, Khalid Sadki, Samson Pandam Salifu, Jumoke Soyemi, Sumir Panji, Fouzia Radouani, Oussama Souiai, Özlem Tastan Bishop
BACKGROUND: Although pockets of bioinformatics excellence have developed in Africa, generally, large-scale genomic data analysis has been limited by the availability of expertise and infrastructure. H3ABioNet, a pan-African bioinformatics network, was established to build capacity specifically to enable H3Africa (Human Heredity and Health in Africa) researchers to analyze their data in Africa. Since the inception of the H3Africa initiative, H3ABioNet's role has evolved in response to changing needs from the consortium and the African bioinformatics community...
March 13, 2017: Global Heart
https://www.readbyqxmd.com/read/28301102/neural-correlates-of-language-variability-in-preschool-aged-boys-with-autism-spectrum-disorder
#13
Letitia R Naigles, Ryan Johnson, Ann Mastergeorge, Sally Ozonoff, Sally J Rogers, David G Amaral, Christine Wu Nordahl
Children with autism vary widely in their language abilities, yet the neural correlates of this language variability remain unclear, especially early in development. Diffusion tensor imaging (DTI) was used to examine diffusivity measures along the length of 18 major fiber tracts in 104 preschool-aged boys with autism spectrum disorder (ASD). The boys were assigned to subgroups according to their level of language development (Low: no/low language, Middle: small vocabulary, High: large vocabulary and grammar), based on their raw scores on the expressive language (EL) and receptive language (RL) sections of the Mullen Scales of Early Learning (MSEL)...
March 16, 2017: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/28300961/vocabulary-of-preschool-children-with-typical-language-development-and-socioeducational-variables
#14
Thaís Cristina da Freiria Moretti, Rita Cristina Sadako Kuroishi, Patrícia Pupin Mandrá
Purpose: To investigate the correlation between age, socioeconomic status (SES), and performance on emissive and receptive vocabulary tests in children with typical language development. Methods: The study sample was composed of 60 preschool children of both genders, aged 3 years to 5 years 11 months, with typical language development divided into three groups: G I (mean age=3 years 6 months), G II (mean age=4 years 4 months) and G III (mean age=5 years 9 months)...
March 9, 2017: CoDAS
https://www.readbyqxmd.com/read/28300954/selection-of-words-for-implementation-of-the-picture-exchange-communication-system-pecs-in-non-verbal-autistic-children
#15
Carine Ferreira, Monica Bevilacqua, Mariana Ishihara, Aline Fiori, Aline Armonia, Jacy Perissinoto, Ana Carina Tamanaha
Purpose: It is known that some autistic individuals are considered non-verbal, since they are unable to use verbal language and barely use gestures to compensate for the absence of speech. Therefore, these individuals' ability to communicate may benefit from the use of the Picture Exchange Communication System - PECS. The objective of this study was to verify the most frequently used words in the implementation of PECS in autistic children, and on a complementary basis, to analyze the correlation between the frequency of these words and the rate of maladaptive behaviors...
March 9, 2017: CoDAS
https://www.readbyqxmd.com/read/28297001/screening-bilingual-preschoolers-for-language-difficulties-utility-of-teacher-and-parent-reports
#16
Emmanuel Peng Kiat Pua, Mary Lay Choo Lee, Susan J Rickard Liow
Purpose: The utility of parent and teacher reports for screening 3 types of bilingual preschoolers (English-first language [L1]/Mandarin-second language[L2], Mandarin-L1/English-L2, or Malay-L1/English-L2) for language difficulty was investigated in Singapore with reference to measures of reliability, validity, sensitivity, and specificity in an English-medium kindergarten setting. Method: The index tests were teachers' ratings of the English language ability of 5-year-olds (N = 85) on the Bilingual Language Assessment Battery (BLAB): Preschool Teacher Report (Pua, Lee, & Rickard Liow, 2013) and parents' ratings of their child's home language ability (N = 78 English-L1, Mandarin-L1, or Malay-L1) on the BLAB: Preschool Parent Report (Pua, Lee, & Rickard Liow, 2013)...
March 13, 2017: Journal of Speech, Language, and Hearing Research: JSLHR
https://www.readbyqxmd.com/read/28291459/clinical-and-magnetic-resonance-spectroscopic-imaging-findings-in-veterans-with-blast-mild-traumatic-brain-injury-and-post-traumatic-stress-disorder
#17
Anthony P Kontos, Anne C Van Cott, Jodilyn Roberts, Jullie W Pan, Monique B Kelly, Jamie McAllister-Deitrick, Hoby P Hetherington
OBJECTIVES: To compare magnetic resonance spectroscopic imaging (MRSI) findings from the hippocampal regions of military veterans with blast-related mild traumatic brain injury (blast mTBI) and post-traumatic stress disorder (PTSD) to those with PTSD only; and to examine the relationship of MRSI findings to cognitive and neuromotor impairment. METHODS: 35 military veterans-23 with blast mTBI and PTSD (blast mTBI/PTSD) and 12 with PTSD only participated in the study...
March 2017: Military Medicine
https://www.readbyqxmd.com/read/28290319/consumer-perception-of-balsamic-vinegar-a-cross-cultural-study-between-korea-and-italy
#18
Luisa Torri, Seon-Young Jeon, Maria Piochi, Gabriella Morini, Kwang-Ok Kim
Understanding cross-cultural differences in food perception is a key issue of food research in order to understand consumer behaviour in different countries. The objective of this study was to explore potential cultural differences of balsamic vinegar perception between Korean and Italian consumers using the sorted napping method. Nine balsamic vinegars different in terms of ingredients, aging time, and origin were evaluated by Korean (n=50) and Italian (n=49) consumers using sorted napping. Familiarity and food matching were also examined...
January 2017: Food Research International
https://www.readbyqxmd.com/read/28287832/computer-scoring-of-emotional-awareness-in-a-nonclinical-population-of-young-adults
#19
Kimberly A Barchard, Caleb J Picker
The Levels of Emotional Awareness Scale (LEAS; Lane, Quinlan, Schwartz, Walker, & Zeitlin, 1990 ) is an open-ended measure of the ability to describe emotional reactions. Scoring the LEAS by hand is complex and time consuming (Barchard, Bajgar, Leaf, & Lane, 2010 ). Therefore, Program for Open-Ended Scoring (POES; Leaf & Barchard, 2010 ) was designed to score the LEAS quickly and easily. Using 268 undergraduates, this article compares traditional LEAS hand scoring to 6 POES methods, 2 of which are holistic methods that have never before been examined...
March 13, 2017: Journal of Personality Assessment
https://www.readbyqxmd.com/read/28287762/predictors-of-verb-mediated-anticipatory-eye-movements-in-the-visual-world
#20
Florian Hintz, Antje S Meyer, Falk Huettig
Many studies have demonstrated that listeners use information extracted from verbs to guide anticipatory eye movements to objects in the visual context that satisfy the selection restrictions of the verb. An important question is what underlies such verb-mediated anticipatory eye gaze. Based on empirical and theoretical suggestions, we investigated the influence of 5 potential predictors of this behavior: functional associations and general associations between verb and target object, as well as the listeners' production fluency, receptive vocabulary knowledge, and nonverbal intelligence...
March 13, 2017: Journal of Experimental Psychology. Learning, Memory, and Cognition
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