Silvia Nardelli, Ilaria Pentassuglio, Chiara Pasquale, Lorenzo Ridola, Federica Moscucci, Manuela Merli, Concetta Mina, Massimo Marianetti, Mariangela Fratino, Chiara Izzo, Carlo Merkel, Oliviero Riggio
HRQoL is impaired in cirrhosis. Establishing the relevance of depression, anxiety, alexithymia and cirrhosis stage on the patients' HRQoL. Sixty cirrhotics underwent a neuropsychological assessment, including ZUNG-SDS, STAI Y1-Y2 and TAS-20. Minimal hepatic encephalopathy (MHE) was detected by PHES, HRQoL by Short-Form-36 (SF-36). Depression was detected in 34 patients (57 %, 95%CI = 44-70 %), state-anxiety in 16 (27 %, 95%CI = 15-38 %), trait-anxiety in 17 (28 %, 95%CI = 17-40 %), alexithymia in 14 (31 % 95%CI = 16-46 %) and MHE in 22 (37 %, 95%CI = 24-49 %)...
June 2013: Metabolic Brain Disease