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https://www.readbyqxmd.com/read/28635451/delivering-person-centred-care-in-police-custody
#1
Matt Peel
The custody nurse role was introduced in 2003 following changes to legislation, which allowed nurses and paramedics to care for people in police custody. Before this, the work was done solely by doctors.
June 21, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28633973/patellofemoral-osteoarthritis-progression-and-alignment-changes-after-open-wedge-high-tibial-osteotomy-do-not-affect-clinical-outcomes-at-mid-term-follow-up
#2
Kenichi Goshima, Takeshi Sawaguchi, Kenji Shigemoto, Shintaro Iwai, Akira Nakanishi, Ken Ueoka
PURPOSE: To evaluate the clinical and radiological outcomes of open-wedge high tibial osteotomy (OWHTO) with respect to the patellofemoral joint and to assess whether patellofemoral osteoarthritis (OA) progression and alignment changes after OWHTO affect clinical outcomes. METHODS: Inclusion criteria were consecutive patients who underwent OWHTO from March 2005 to September 2013. Exclusion criteria were loss to follow-up within 2 years and absence of second-look arthroscopy findings at the time of plate removal...
June 17, 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/28632340/prescribing-in-the-oldest-old-inpatients-a-retrospective-analysis-of-patients-referred-for-specialist-geriatric-consultation
#3
Sivarajah Ilango, Peter Pillans, Nancye M Peel, Ian Scott, Leonard C Gray, Ruth E Hubbard
INTRODUCTION: While medications may prolong life and prevent morbidity in older people, adverse effects of polypharmacy are increasingly recognised. As patients age and become frail, prescribing may be expected to focus more on symptom control and minimise potentially harmful preventive medication use that confer little benefit within a short lifespan. Whether prescribing practice shifts to one of symptom control among the oldest old admitted to hospital remains unclear. METHODS: Retrospective analysis of all patients aged ≥85 years referred for comprehensive geriatric assessment at a tertiary care hospital between May 2006 and December 2014 for whom all prescribed medications were documented...
June 20, 2017: Internal Medicine Journal
https://www.readbyqxmd.com/read/28631804/mandarin-fruit-quality-a-review
#4
REVIEW
Livnat Goldenberg, Yossi Yaniv, Ron Porat, Nir Carmi
During the last decade, there has been a continuous rise in consumption and global marketing of fresh, easy-to-peel mandarins, with current annual production of nearly 29 million tons. Nevertheless, most of the existing knowledge on quality traits of citrus fruit comes from research conducted on oranges and grapefruit, which are the main products for the citrus juice manufacturing industry; relatively little is yet known regarding the unique fruit quality traits of mandarins, nor about the great diversity in these traits among the various natural sub-groups and varieties of mandarins...
June 20, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28631180/microvascular-changes-after-vitrectomy-with-internal-limiting-membrane-peeling-an-optical-coherence-tomography-angiography-study
#5
Leonardo Mastropasqua, Enrico Borrelli, Paolo Carpineto, Lisa Toto, Luca Di Antonio, Peter A Mattei, Rodolfo Mastropasqua
PURPOSE: To evaluate superficial capillary plexus (SCP) changes occurring after internal limiting membrane (ILM) peeling for the treatment of idiopathic epiretinal membrane (ERM). METHODS: A total of 15 eyes of 15 patients affected by idiopathic ERM (eight males and seven females; mean age 59.8 ± 9.6 years) were enrolled in the study. Patients were treated with pars plana vitrectomy followed by ERM and ILM peeling. Subjects were evaluated at baseline and at the week-1 and month-1 follow-up visits...
June 19, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28630788/evaluation-of-ganglion-cell-inner-plexiform-layer-thickness-after-vitreoretinal-surgery-with-internal-limiting-membrane-peeling-in-cases-with-idiopathic-macular-hole
#6
Sibel Demirel, Ahmed Abdullayev, Özge Yanık, Figen Batıoğlu, Emin Özmert
OBJECTIVES: To evaluate macular retinal ganglion cell-inner plexiform layer (GCIPL) thickness after vitrectomy with internal limiting membrane (ILM) peeling for idiopathic macular holes using spectral domain optical coherence tomography (SD-OCT). MATERIALS AND METHODS: Eighteen eyes of 18 patients with unilateral idiopathic macular hole who underwent vitrectomy with ILM peeling were retrospectively analyzed. Healthy fellow eyes of the patients and 18 eyes of 18 age-matched healthy individuals constituted the control group...
June 2017: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/28629701/a-polymethoxyflavone-mixture-extracted-from-orange-peels-mainly-containing-nobiletin-3-3-4-5-6-7-8-heptamethoxyflavone-and-tangeretin-suppresses-melanogenesis-through-the-acidification-of-cell-organelles-including-melanosomes
#7
Norihiro Yoshizaki, Ron Hashizume, Hitoshi Masaki
BACKGROUND: Skin color is determined by melanin contents and its distribution. Melanin is synthesized in melanosomes of melanocytes, catalyzed by tyrosinase, melanogenic enzymes. Regarding the process of melanin synthesis, melanosomal pH is considered to play an important role, because it has been reported to differ between Caucasian and Black melanocytes. OBJECTIVE: Although polymethoxyflavone (PMF) has many beneficial effects, it has not been reported which PMF suppresses melanogenesis...
June 10, 2017: Journal of Dermatological Science
https://www.readbyqxmd.com/read/28629648/ten-reasons-to-embrace-scientism
#8
Rik Peels
A strong version of scientism, such as that of Alex Rosenberg, says, roughly, that natural science reliably delivers rational belief or knowledge, whereas common sense sources of belief, such as moral intuition, memory, and introspection, do not. In this paper I discuss ten reasons that adherents of scientism have or might put forward in defence of scientism. The aim is to show which considerations could plausibly count in favour of scientism and what this implies for the way scientism ought to be formulated...
June 2017: Studies in History and Philosophy of Science
https://www.readbyqxmd.com/read/28627756/microcontact-peeling-a-cell-micropatterning-technique-for-circumventing-direct-adsorption-of-proteins-to-hydrophobic-pdms
#9
Sho Yokoyama, Tsubasa S Matsui, Shinji Deguchi
Microcontact printing (μCPr) is one of the most popular techniques used for cell micropatterning. In conventional μCPr, a polydimethylsiloxane (PDMS) stamp with microfeatures is used to adsorb extracellular matrix (ECM) proteins onto the featured surface and transfer them onto particular areas of a cell culture substrate. However, some types of functional proteins other than ECM have been reported to denature upon direct adsorption to hydrophobic PDMS. Here we describe a detailed protocol of an alternative technique--microcontact peeling (μCPe)--that allows for cell micropatterning while circumventing the step of adsorbing proteins to bare PDMS...
June 19, 2017: Current Protocols in Cell Biology
https://www.readbyqxmd.com/read/28627245/phytochemical-screening-and-in-vitro-evaluation-of-pharmacological-activities-of-peels-of-musa-sapientum-and-carica-papaya-fruit
#10
Sarmad Siddique, Shamsa Nawaz, Faqir Muhammad, Bushra Akhtar, Bilal Aslam
Aqueous, absolute and 80% ethanolic extract of fruit peels of Musa sapientum and Carica papaya were investigated for their antibacterial activity, measured by disc diffusion method and antioxidant activity, measured by four different methods. Papaya and banana peels were found to contain terpenoids, tannins, alkaloids, saponins steroid, phenols, fixed oils and fats. 80% ethanolic extract of banana peel was found to contain highest total phenolic content (TPC), total flavonoid content (TFC) and antioxidant activity but in papaya peel, highest TPC and reducing activity was shown by water extract while, TFC and radical scavenging activity was given by 80% ethanolic extract...
June 18, 2017: Natural Product Research
https://www.readbyqxmd.com/read/28626138/evaluation-of-sorption-mechanism-of-pb-ii-andni-ii-onto-pea-pisum-sativum-peels
#11
Atta Ul Haq, Muhammad Saeed, Salma Anjum, Tanveer Hussain Bokhari, Muhammad Usman, Saiqa Tubbsum
The present study was carried out to know the sorption mechanism of Pb (II) and Ni (II) in aqueous solution using pea peels under the influence of sorbent dose, pH, temperature, initial metal ion concentration and contact time. SEM and FTIR were used for characterization of pea peels. The study showed that solution pH affects sorption process and the optimum pH for Pb (II) was 6.0 while for that of Ni (II) was 7.0. Pseudo-second order kinetic model was found to be the most suitable one to explain the kinetic data not only due to high value of R(2) (>0...
June 13, 2017: Journal of Oleo Science
https://www.readbyqxmd.com/read/28623504/biosorption-of-chromium-vi-from-aqueous-solutions-and-ann-modelling
#12
Soma Nag, Abhijit Mondal, Nirjhar Bar, Sudip Kumar Das
The use of sustainable, green and biodegradable natural wastes for Cr(VI) detoxification from the contaminated wastewater is considered as a challenging issue. The present research is aimed to assess the effectiveness of seven different natural biomaterials, such as jackfruit leaf, mango leaf, onion peel, garlic peel, bamboo leaf, acid treated rubber leaf and coconut shell powder, for Cr(VI) eradication from aqueous solution by biosorption process. Characterizations were conducted using SEM, BET and FTIR spectroscopy...
June 16, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28622618/recovery-and-purification-of-limonin-from-pummelo-citrus-grandis-peel-using-water-extraction-ammonium-sulfate-precipitation-and-resin-adsorption
#13
Yuan Fan Yang, Liang Zheng Zhang, Xi Ping Du, Su Fang Zhang, Li Jun Li, Ze Dong Jiang, Li Ming Wu, Hui Ni, Feng Chen
Limonin is a bioactive compound that is traditionally extracted from citrus seeds using organic solvents or alkaline/metal ion solutions. In the present study, pummelo [Citrus grandis] peel was investigated for limonin preparation using a novel process consisting of water extraction, ammonium sulfate precipitation and resin adsorption. The pummelo peel was determined to have 4.7mg/g limonin, which could be extracted by water and further recovered by ammonium sulfate precipitation with a yield of 2.4mg/g, which was similar to that of traditional process using ethanol extraction and vacuumed evaporation...
June 3, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/28622601/immobilisation-of-barley-aleurone-layers-enables-parallelisation-of-assays-and-analysis-of-transient-gene-expression-in-single-cells
#14
Kinga Zór, Christina Mark, Arto Heiskanen, Claus Krogh Madsen, Martin Dufva, Jenny Emnéus, Henrik Brinch-Pedersen, Christine Finnie
The barley aleurone layer is an established model system for studying phytohormone signalling, enzyme secretion and programmed cell death during seed germination. Most analyses performed on the aleurone layer are end-point assays based on cell extracts, meaning each sample is only analysed at a single time point. By immobilising barley aleurone layer tissue on polydimethylsiloxane pillars in the lid of a multiwell plate, continuous monitoring of living tissue is enabled using multiple non-destructive assays in parallel...
June 8, 2017: Plant Physiology and Biochemistry: PPB
https://www.readbyqxmd.com/read/28622372/vitrectomy-with-or-without-internal-limiting-membrane-peeling-for-idiopathic-epiretinal-membrane-a-meta-analysis
#15
Wei-Cheng Chang, Chin Lin, Cho-Hao Lee, Tzu-Ling Sung, Tao-Hsin Tung, Jorn-Hon Liu
BACKGROUND: Studies on vitrectomy with and without internal limiting membrane (ILM) peeling for idiopathic epiretinal membrane (ERM) have yielded uncertain results regarding clinical outcomes and recurrence rates. OBJECTIVE: To compare the clinical outcomes of vitrectomy with and without ILM peeling for idiopathic ERM. METHODS: Databases, including PubMed, Embase, Cochrane, Web of Science, Google Scholar, CNKI databases, FDA.gov, and ClinicalTrials...
2017: PloS One
https://www.readbyqxmd.com/read/28620727/investigation-of-trace-element-content-in-the-seeds-pulp-and-peel-of-mashui-oranges-using-microwave-digestion-and-icp-ms-analysis
#16
Lingyun Chen, Mei Shen, Ande Ma, Weili Han
Fresh Mashui orange samples were pretreated with microwave digestion using an HNO3-H2O2 system. The levels of Mg, K, Ca, Fe, Mn, Cu, Zn, As, Cd, and Pb in the seeds, pulp, and peel were then determined using inductively coupled plasma mass spectrometry (ICP-MS) combined with collision cell technology (CCT) and kinetic energy discrimination (KED). The standard curve coefficient of determinations of the ten tested elements were between 0.9995 and 0.9999. The instrument detection limit was between 0.112 ng/L and 3...
June 16, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28618106/authors-response
#17
Amanda Wilson, David Smith, Roseanne Peel, Jane Robertson, Kypros Kypri
No abstract text is available yet for this article.
June 15, 2017: Australian and New Zealand Journal of Public Health
https://www.readbyqxmd.com/read/28617100/discovery-of-potent-and-selective-acetylcholinesterase-ache-inhibitors-acacetin-7-o-methyl-ether-mannich-base-derivatives-synthesised-from-easy-access-natural-product-naringin
#18
Hao-Ran Liu, Xue Men, Xiao-Hui Gao, Lin-Bo Liu, Hao-Qun Fan, Xin-Hua Xia, Qiu-An Wang
Naringin, as a component universal existing in the peel of some fruits or medicinal plants, was usually selected as the material to synthesise bioactive derivates since it was easy to gain with low cost. In present investigation, eight new acacetin-7-O-methyl ether Mannich base derivatives (1-8) were synthesised from naringin. The bioactivity evaluation revealed that most of them exhibited moderate or potent acetylcholinesterase (AChE) inhibitory activity. Among them, compound 7 (IC50 for AChE = 0.82 ± 0...
June 15, 2017: Natural Product Research
https://www.readbyqxmd.com/read/28615062/metabolic-and-transcriptional-elucidation-of-the-carotenoid-biosynthesis-pathway-in-peel-and-flesh-tissue-of-loquat-fruit-during-on-tree-development
#19
Margarita Hadjipieri, Egli C Georgiadou, Alicia Marin, Huertas M Diaz-Mula, Vlasios Goulas, Vasileios Fotopoulos, Francisco A Tomás-Barberán, George A Manganaris
BACKGROUND: Carotenoids are the main colouring substances found in orange-fleshed loquat fruits. The aim of this study was to unravel the carotenoid biosynthetic pathway of loquat fruit (cv. 'Obusa') in peel and flesh tissue during distinct on-tree developmental stages through a targeted analytical and molecular approach. RESULTS: Substantial changes regarding colour parameters, both between peel and flesh and among the different developmental stages, were monitored, concomitant with a significant increment in carotenoid content...
June 14, 2017: BMC Plant Biology
https://www.readbyqxmd.com/read/28611849/nonparametric-subgroup-identification-by-prim-and-cart-a-simulation-and-application-study
#20
Armin Ott, Alexander Hapfelmeier
Two nonparametric methods for the identification of subgroups with outstanding outcome values are described and compared to each other in a simulation study and an application to clinical data. The Patient Rule Induction Method (PRIM) searches for box-shaped areas in the given data which exceed a minimal size and average outcome. This is achieved via a combination of iterative peeling and pasting steps, where small fractions of the data are removed or added to the current box. As an alternative, Classification and Regression Trees (CART) prediction models perform sequential binary splits of the data to produce subsets which can be interpreted as subgroups of heterogeneous outcome...
2017: Computational and Mathematical Methods in Medicine
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