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https://www.readbyqxmd.com/read/28930450/continuous-sorting-of-cells-based-on-differential-p-selectin-glycoprotein-ligand-expression-using-molecular-adhesion
#1
Bushra Tasadduq, Brynn Mcfarland, Muhymin Islam, Alexander Alexeev, Ali Fatih Sarioglu, Todd A Sulchek
Cell surface molecular adhesions govern many important physiological processes and are used to identify cells for analysis and purifications. But most effective cell adhesion separation technologies use labels or long-term attachments in their application. While label-free separation microsystems typically separate cells by size, stiffness, and shape, they often do not provide sufficient specificity to cell type that can be obtained from molecular expression. We demonstrate a label-free microfluidic approach capable of high throughput separation of cells based upon surface molecule adhesion...
September 20, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28930433/high-resolution-graphene-films-for-electrochemical-sensing-via-inkjet-maskless-lithography
#2
John A Hondred, Loreen R Stromberg, Curtis L Mosher, Jonathan C Claussen
Solution-phase printing of nanomaterial-based graphene inks are rapidly gaining interest for fabrication of flexible electronics. However, scalable manufacturing techniques for high-resolution printed graphene circuits are still lacking. Here, we report a patterning technique [i.e., inkjet maskless lithography (IML)] to form high resolution, flexible, graphene films (line widths down to 20 µm) that significantly exceeds the current inkjet printing resolution of graphene (line widths ~ 60 µm). IML uses an inkjet printed polymer lacquer as a sacrificial pattern, viscous spin coated graphene, and a subsequent graphene lift-off to patterned films without the need for pre-fabricated stencils, templates or cleanroom technology (e...
September 20, 2017: ACS Nano
https://www.readbyqxmd.com/read/28929542/visuomotor-effects-of-body-part-movements-presented-in-the-first-person-perspective-on-imitative-behavior
#3
Rui Watanabe, Takahiro Higuchi, Yoshiaki Kikuchi, Masato Taira
Imitative stimuli presented from a first-person perspective (FPP) produce stronger visuomotor effects than those presented from a third-person perspective (TPP) due to the relatively greater response of the mirror neuron system (MNS) to FPP stimuli. Some previous studies utilizing TPP stimuli have reported no differences in MNS activity between moving and static bodies' stimuli. However, few studies have compared visuomotor effects of such stimuli when presented in the FPP. To clarify this issue, we measured cortical activation in 17 participants during a functional magnetic resonance imaging (MRI) imitation task involving three conditions: moving (a lifting finger was presented), static (an "X" appeared on a static finger), and control (an "X" appeared on a button)...
September 20, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/28929325/computational-fluid-dynamics-cfd-analysis-of-airlift-bioreactor-effect-of-draft-tube-configurations-on-hydrodynamics-cell-suspension-and-shear-rate
#4
Sanjay B Pawar
The biomass productivity of microalgae cells mainly depends on the hydrodynamics of airlift bioreactor (ABR). Thus, the hydrodynamics of concentric tube ABR was initially studied using two-phase three-dimensional CFD simulations with the Eulerian-Lagrangian approach. The performance of ABR (17 L) was examined for different configurations of the draft tube using various drag models such as Grace, Ishii-Zuber, and Schiller-Naumann. The gas holdups in the riser and the downcomer were well predicted using E-L approach...
September 19, 2017: Bioprocess and Biosystems Engineering
https://www.readbyqxmd.com/read/28928584/a-randomized-study-comparing-the-sniffing-position-with-simple-head-extension-for-glottis-visualization-and-difficulty-in-intubation-during-direct-laryngoscopy
#5
Mehmooda Akhtar, Zulfiqar Ali, Nelofar Hassan, Saqib Mehdi, Gh Mohammad Wani, Aabid Hussain Mir
BACKGROUND: Proper positioning of the head and neck is important for an optimal laryngeal visualization. Traditionally, sniffing position (SP) is recommended to provide a superior glottic visualization, during direct laryngoscopy, enhancing the ease of intubation. Various studies in the last decade of this belief have challenged the need for sniffing position during intubation. We conducted a prospective study comparing the sniffing head position with simple head extension to study the laryngoscopic view and intubation difficulty during direct laryngoscopy...
July 2017: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/28928049/role-for-cementoplasty-in-intra-articular-distal-radius-fractures-cadaver-study-and-application-to-arthroscopy
#6
V Fontaine, M Grunberg, J Soret, K El-Youssef, L E Gayet, R Taberne
BACKGROUND: Die-punch intra-articular fractures of the distal radius raise surgical challenges. The residual articular step-off must be less than 1mm to prevent the development of radio-carpal osteoarthritis. The objectives of this cadaver study were to evaluate whether cementoplasty was effective in reducing die-punch fractures and to determine whether this technique was feasible as an arthroscopic procedure. HYPOTHESIS: Cementoplasty performed as an arthroscopic procedure is effective in treating die-punch fractures...
September 16, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/28927806/-aging-prevention-new-surgical-techniques-and-future-options-for-facial-rejuvenation
#7
C Le Louarn
Prevention of aging is mainly obtained through appropriate health practices, modulated by the genetic causes of aging. Causes of facial structural aging include gravity, volume loss, contraction of the mimic muscles and obviously biological aging of tissues. Among the very numerous new surgical technique of facial rejuvenation, we could point out: for the frontal region, obviously we are focus on the endoscopic and non-endoscopic frontal lifts. But also, we should note the transcutaneous Brow Shaping which with a well defined, step by step technique is indeed a simple way to improve a possible difficult situation; concerning the mid-face lift, as the main risk is the secondary eyelid malposition, a high Smas or a temporo-malar lift can be performed...
September 15, 2017: Annales de Chirurgie Plastique et Esthétique
https://www.readbyqxmd.com/read/28927496/occupational-strain-as-a-risk-for-hip-osteoarthritis
#8
Annekatrin Bergmann, Ulrich Bolm-Audorff, Daniel Krone, Andreas Seidler, Falk Liebers, Johannes Haerting, Alice Freiberg, Susanne Unverzagt
BACKGROUND: Multiple epidemiological studies have revealed an association between occupational physical strain and the risk of developing hip osteoarthritis. METHODS: To determine the association between the lifting and carrying of heavy loads or other physically demanding work and the risk of hip osteoarthritis (HOA) or total hip replacement (THR), we systematically searched the literature for primary studies on the effects of exposure to physical strain and meta-analytically reviewed the results that were amenable to comparisons across studies...
September 4, 2017: Deutsches Ärzteblatt International
https://www.readbyqxmd.com/read/28922042/reliability-and-criterion-validity-of-measurements-using-a-smart-phone-based-measurement-tool-for-the-transverse-rotation-angle-of-the-pelvis-during-single-leg-lifting
#9
Sung-Hoon Jung, Oh-Yun Kwon, In-Cheol Jeon, Ui-Jae Hwang, Jong-Hyuck Weon
OBJECTIVE: The purposes of this study were to determine the intra-rater test-retest reliability of a smart phone-based measurement tool (SBMT) and a three-dimensional (3D) motion analysis system for measuring the transverse rotation angle of the pelvis during single-leg lifting (SLL) and the criterion validity of the transverse rotation angle of the pelvis measurement using SBMT compared with a 3D motion analysis system (3DMAS). METHOD: Seventeen healthy volunteers performed SLL with their dominant leg without bending the knee until they reached a target placed 20 cm above the table...
September 18, 2017: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/28921521/a-paradigm-for-evaluation-and-management-of-the-maxillary-sinus-before-dental-implantation
#10
Yi-Wei Chen, Fu-Ying Lee, Po-Hung Chang, Chi-Che Huang, Chia-Hsiang Fu, Chien-Chia Huang, Ta-Jen Lee
OBJECTIVES: To determine a paradigm for evaluating and managing maxillary sinus conditions before dental implantation via preoperative sinonasal assessment. STUDY DESIGN: Prospective cohort study. METHODS: Eighty-four patients who underwent dental implantation with or without sinus augmentation were included. Maxillary sinus conditions were classified into groups 1 to 6 according to cone-beam computed tomography (CT) findings: 1) nonspecific findings, 2) solitary polyp or cyst, 3) mucosal thickening, 4) air-fluid level or fluid accumulation, 5) near-total opacification of the maxillary or other paranasal sinus, and 6) calcification spots in the maxillary sinus...
September 16, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28920760/influence-analysis-for-the-area-under-the-receiver-operating-characteristic-curve
#11
Bo-Shiang Ke, An Jen Chiang, Yuan-Chin Ivan Chang
Classification measures play essential roles in the assessment and construction of classifiers. Hence, determining how to prevent these measures from being affected by individual observations has become an important problem. In this paper, we propose several indexes based on the influence function and the concept of local influence to identify influential observations that affect the estimate of the area under the receiver operating characteristic curve (AUC), an important and commonly used measure. Cumulative lift charts are also used to equipoise the disagreements among the proposed indexes...
September 18, 2017: Journal of Biopharmaceutical Statistics
https://www.readbyqxmd.com/read/28919134/-the-eyelid-cheek-junction
#12
C Volpei, J Fernandez, B Chignon-Sicard
The eyelid-cheek junction is a key area which generates many comments: from looking tired to looking good or rested, without forgetting charm, beauty, and a youthful appearance. In spite of many interesting medical and surgical procedures, treating this area is sometimes difficult and results are not always up to our expectations. Standardized blepharoplasty, which has often been improperly used, has shown its limits. Since the latest refinements, lipostructure has revolutionised blepharoplasty and serving as a reference, it has become an established technique...
September 14, 2017: Annales de Chirurgie Plastique et Esthétique
https://www.readbyqxmd.com/read/28918696/nature-of-injury-and-risk-of-multiple-claims-among-workers-in-manitoba-health-care
#13
Nelson Ositadimma Oranye
In industrial societies, work-related musculoskeletal disorders are common among workers, frequently resulting in recurrent injuries, work disability, and multiple compensation claims. The risk of idiopathic musculoskeletal injuries is thought to be more than twice the risk of any other health problem among workers in the health care sector. This risk is highly prevalent particularly among workers whose job involves frequent physical tasks, such as patient lifting and transfer. Workers with recurrent occupational injuries are likely to submit multiple work disability claims and progress to long-term disability...
September 1, 2017: Workplace Health & Safety
https://www.readbyqxmd.com/read/28918340/-cervical-lift-an-update
#14
D Labbé, P Guerreschi
The neck is an aesthetic unit for which a rejuvenation request is sometimes very targeted or ore often encompassed in a global surgical project of face-lift. To obtain a long lasting outcome, the plastic surgeon has to make a full, detailed, and exhaustive analysis of the neck in order to choose the best indication within the multiple surgical tools. A full clinical examination is the key point, every aspects are outlined. The numerous surgical choices are described, illustrated, and sometimes revisited in the light of targeted anatomical studies...
September 13, 2017: Annales de Chirurgie Plastique et Esthétique
https://www.readbyqxmd.com/read/28918200/profiling-the-short-linear-non-disulfide-bond-containing-peptidome-from-the-venom-of-the-scorpion-tityus-obscurus
#15
Nathalia Baptista Dias, Bibiana Monson de Souza, Fernando Kamimura Cocchi, Hipócrates M Chalkidis, Valquíria Abrão Coronado Dorce, Mario Sergio Palma
Many scorpion accidents occur in the Brazilian Amazonian region and are frequently caused by Tityus obscurus. Approximately 5% of the crude venom of this species is composed of short linear, non-disulfide-bridged peptides, which have not been intensively investigated. As a consequence, only a few of these peptides have been structurally and functionally characterized to date. In the present paper, the peptide fraction of the venom was subjected to peptide profiling using an LCMS-IT-TOF/MS and MS(n) system. The analysis detected 320 non-disulfide bond-containing peptides (NDBPs), of which twenty-seven had their sequences assigned; among them, thirteen peptides were characterized, constituting novel toxins in T...
September 13, 2017: Journal of Proteomics
https://www.readbyqxmd.com/read/28917905/characterization-of-a-water-soluble-chitosan-derivative-and-its-potential-for-submucosal-injection-in-endoscopic-techniques
#16
Hidemi Hattori, Hironori Tsujimoto, Kazuo Hase, Masayuki Ishihara
To examine the potential of chitosan-based agents for submucosal injection in endoscopic techniques, a chitosan derivative was prepared with lactose moieties linked to the amino groups of its glucosamine units (CH-LA). After dissolving CH-LA in neutral pH solutions, including physiological saline (CH-LA-S), its response to different concentrations of anionic glycosaminoglycans and proteins in the surrounding environment was examined. The CH-LA-S form changed in the presence of sulfated glycosaminoglycans (heparin, chondroitin sulfate, and mucin) and protein (fibrinogen)...
November 1, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28915290/lifting-the-lower-face-with-an-absorbable-polydioxanone-pdo-thread
#17
Kian Karimi, Alexandra Reivitis
Traditional rejuvenation techniques include chemical peels, rhytidectomy of the skin, laser resurfacing, injection of dermal fillers and neurotoxins, and invasive surgical procedures. Patients with brow ptosis, jowl formation, and deepening nasolabial folds currently seek antiaging procedures with no incisions and minimal downtime such as thread-lifting with barbed sutures. The present report describes a case in which polydioxanone threads were used to lift the lower third of a patient's face. Fillers were used to supplement the results achieved by the thread lift because often, when tissue has been lifted, volume deficits are revealed, which can be corrected with dermal fillers...
September 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/28914719/physical-therapy-management-of-patients-with-chronic-low-back-pain-and-hip-abductor-weakness
#18
Seth Peterson, Thomas Denninger
BACKGROUND AND PURPOSE: Hip abductor dysfunction is common in individuals with chronic low back pain (CLBP). Previous research investigating abductor strengthening in the heterogeneous CLBP population is sparse and has failed to target those patients most likely to benefit. The aim of the current case series was to describe the physical therapy management and outcomes of 3 patients with CLBP matching a previously identified subgroup characterized by substantial hip abductor weakness. CASE DESCRIPTION: Three nonconsecutive patients with CLBP-a 77-year-old man, a 78-year-old woman, and an 85-year-old woman-were treated in an outpatient physical therapy clinic...
September 13, 2017: Journal of Geriatric Physical Therapy
https://www.readbyqxmd.com/read/28913505/periorbital-facial-rejuvenation-applied-anatomy-and-pre-operative-assessment
#19
REVIEW
Mohsen Bahmani Kashkouli, Parya Abdolalizadeh, Navid Abolfathzadeh, Hamed Sianati, Maria Sharepour, Yasaman Hadi
PURPOSE: Since different subspecialties are currently performing a variety of upper facial rejuvenation procedures, and the level of knowledge on the ocular and periocular anatomy and physiology is different, this review aims to highlight the most important preoperative examinations and tests with special attention to the eye and periocular adnexal structures for general ophthalmologist and specialties other than oculo-facial surgeons in order to inform them about the fine and important points that should be considered before surgery to have both cosmetic and functional improvement...
September 2017: Journal of Current Ophthalmology
https://www.readbyqxmd.com/read/28912615/why-the-moratorium-on-human-animal-chimera-research-should-not-be-lifted
#20
Alan Moy
The National Institutes of Health (NIH) announced its plans to lift its moratorium on funding research that involves injecting human embryonic stem cells into animal embryos, which would allow for the creation of part-human and part-animal organisms known as chimeras. The NIH allowed only one month to receive public comments in the midst of a presidential election campaign. Lifting the moratorium means that, for the first time, the federal government will begin spending taxpayer dollars on the creation and manipulation of new organisms that would blur the line between humans and animals...
August 2017: Linacre Quarterly
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