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Parathyroid cysts

Funda Sari, Ayca Inci, Suleyman Dolu, Hamit Yasar Ellidag, Ramazan Cetinkaya, Fettah Fevzi Ersoy
This study aims to determine fibroblast growth factor-23 and soluble α-Klotho levels in patients with autosomal dominant polycystic kidney disease. A total of 76 patients with autosomal dominant polycystic kidney disease and 32 healthy volunteers were included in the study. Serum fibroblast growth factor-23 and soluble α-Klotho levels were measured with ELISA kits. Parathyroid hormone, phosphate, calcium, creatinine, 25-hydroxyvitamin D3 levels, urinary protein to creatinine ratio and estimated glomerular filtration rate were also measured or calculated...
October 12, 2016: Journal of Investigative Medicine: the Official Publication of the American Federation for Clinical Research
Marco Mele, Lars Rolighed, MarieLouise Jespersen, Lars Rejnmark, Peer Christiansen
INTRODUCTION: Cancer in the parathyroid gland is rare, but parathyroid cancer is occasionally seen in relation to genetic abnormalities. Due to a limited amount of evidence, the optimal handling of these cases is not clear. Furthermore, the presence of a malignant parathyroid tumor is rarely known at the time of the initial operation; therefore, re-operations are often necessary. The aim of this study was to present the case of a patient with a previously diagnosed jaw tumor and parathyroid carcinoma that presents as a recurrence of hyperparathyroid hypercalcemia...
April 2016: International Journal of Endocrinology and Metabolism
Kaori Isobe, Sydney Mukaratirwa, Claudio Petterino, Alys Bradley
The incidence and range of spontaneous thyroid and parathyroid glands findings were determined in control Han-Wistar and Sprague-Dawley rats, and CD-1 mice from 104-week carcinogenicity studies carried out between 1998 and 2010 at Charles River Edinburgh. In both strains of rats and in CD-1 mice, non-proliferative lesions of the thyroid or parathyroid glands were generally uncommon apart from some findings in CD-1 mice such as ultimobranchial duct/cyst (5.72%), follicular distension/dilatation (3.84%), and cystic follicles (3...
July 2016: Journal of Toxicologic Pathology
J M Yin, J Chi, Z Y Fu, W L Chen, Y F Liu, L Zhu
No abstract text is available yet for this article.
June 7, 2016: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
H Shen, B B Wei, Z X Peng
OBJECTIVE: To study the pathological and clinical features and the surgical results of the mass in the pretracheal space. METHODS: From 1999 to 2004, 8 females and 3 males with an average of 43 years (from 32 to 61 years) were included CT scan, nuclear imaging, ultrasound and ultrasound-guided aspiration, endoscopic and laboratory measure were used in the evaluation for the masses before operation. Complete removal of mass was carried out in all patients under general anesthesia, and continuous negative pressure draining was routinely used...
June 7, 2016: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
Adriana Handra-Luca, Ema Dragoescu
Thyroid lymphoepithelial complexes (LECos) are rare, being reported in lymphoma, Graves-Basedow disease, Hashimoto thyroiditis, pericarcinomatous thyroid or in the context of branchial cleft-like cysts. Here we report immunohistochemical expression of cytokeratin 5/6, P63 and TTF1 in 6 cases of thyroid LECos. Two cases had carbimazole treatment for hyperthyroidia and Graves disease. Anti-thyroglobulin, -thyroperoxidase or -TSH antibodies were detected in 4 cases. NSAID or poviodone iodine allergy were present in 2 cases...
August 2016: Annals of Diagnostic Pathology
Vincenzo De Sanctis, Ashraf T Soliman, Salvatore Di Maio, Heba Elsedfy, Nada A Soliman, Rania Elalaily
Thyroid hemiagenesis (TH) is a rare congenital abnormality of the thyroid gland, characterised by the absence of one lobe. The true prevalence of this congenital abnormality is not known because the absence of one thyroid lobe usually does not cause clinical symptoms by itself. Between 1970 and 2010, 329 cases of TH have been reported. It is interesting to note that most cases have an agenesis of the left lobe (80% of cases) followed by the isthmus (44-50% of cases). Although the female to male ratio was 1:1...
March 2016: Pediatric Endocrinology Reviews: PER
Xiangdang Yin, Liang Hu, Xiaochun Wang
OBJECTIVE: To evaluate the effects of thyroid cystectomy for primary hyperparathyroidism on immune function. METHODS: Ninety-two patients with parathyroid cysts complicated with primary hyperparathyroidism were randomly divided into a treatment group and a control group (n=46). The treatment group received endoscopic thyroidectomy through the anterior chest wall via the areolar approach, and the control group was treated with conventional open thyroidectomy. RESULTS: The two groups had similar immune function indices as well as thyroid hormone, serum calcium and phosphorus levels before surgery (P>0...
January 2016: Pakistan Journal of Medical Sciences Quarterly
X U Zhang, Jun-Hui Yuan, L U Feng, Dong-Qiu Shan, Jun-Fu Wu, Shan-Ting Liu
Giant parathyroid cysts (PCs) are a rare entity and possess a benign clinical course. PCs may be functional or non-functional, depending on the ability of the cyst to secrete parathyroid hormone (PTH). The present study reports a rare case of a giant PC in a 56-year-old male who presented to the Affiliated Tumor Hospital, Zhengzhou University (Zhengzhou, Henan, China) with a 10-month history of exertional dyspnea, associated with mild dysphagia that had persisted for 3 months. The present study reviews the clinical situation, laboratory examination, radiographic findings, treatment and prognosis of the patient, and provides a brief discussion regarding the associated literature...
March 2016: Oncology Letters
Rino Buzzola, Lilamani Romayne Kurukulasuriya, Mariana Touza, Norman S Litofsky, Stephen Brietzke, James R Sowers
BACKGROUND: Multiple endocrine neoplasia (MEN) type 1 syndrome is an uncommon inherited disorder characterized by the occurrence of tumors involving two or more endocrine glands. These tumors include pheochromocytoma, adrenal cortical and neuroendocrine tumors including (bronchopulmonary, thymic, gastric), lipomas, angiofibromas, collagenomas, and meningiomas. MEN-4 is very rare and has been characterized by the occurrence of parathyroid and anterior pituitary tumors in association with tumors of the adrenals, kidneys, and reproductive organs...
February 2016: Cardiorenal Medicine
Magda H A Nasreldin, Eman A Ibrahim, Somaia A Saad El-Din
Branchial pouch-derived anomalies may arise from remnants of the first, second, or third/fourth branchial arches. Branchial pouch-related structures are found within the thyroid gland in the form of solid cell rests, epithelial lined cyst with or without an associated lymphoid component, thymic and/or parathyroid tissue, and less commonly in the form of heterotopic cartilage. We present a rare case of left solid thyroid swelling nearby two cervical nodules in a seven-year-old female with a clinical diagnosis suggestive of malignant thyroid tumor with metastasis to the cervical lymph nodes...
2016: Clinical Medicine Insights. Pathology
Ayse Arduc, Yasemin Ates Tutuncu, Bercem Aycicek Dogan, Ayse Burcu Arikan Ileri, Mazhar Muslum Tuna, Hatice Nursun Ozcan, Serhat Isik, Dilek Berker, Serdar Guler
No abstract text is available yet for this article.
April 2015: American Surgeon
Annerose Berndt, Cheryl Ackert-Bicknell, Kathleen A Silva, Victoria E Kennedy, Beth A Sundberg, Justin M Cates, Paul N Schofield, John P Sundberg
Fibro-osseous lesions in mice are progressive aging changes in which the bone marrow is replaced to various degrees by fibrovascular stroma and bony trabeculae in a wide variety of bones. The frequency and severity varied greatly among 28 different inbred mouse stains, predominantly affecting females, ranging from 0% for 10 strains to 100% for KK/HlJ and NZW/LacJ female mice. Few lesions were observed in male mice and for 23 of the strains, no lesions were observed in males for any of the cohorts. There were no significant correlations between strain-specific severities of fibro-osseous lesions and ovarian (r=0...
February 2016: Experimental and Molecular Pathology
Erkin Sonmez, Tugan Tezcaner, Ilker Coven, Aysen Terzi
Brown tumors also called as osteoclastomas, are rare nonneoplastic lesions that arise in the setting of primary or secondary hyperparathyroidism. Parathyroid adenomas or hyperplasia constitute the major Brown tumor source in primary hyperparathyroidism while chronic renal failure is the leading cause in secondary hyperparathyroidism. Most of the patients with the diagnosis of primary hyperparathyroidism present with kidney stones or isolated hypercalcemia. However, nearly one third of patients are asymptomatic and hypercalcemia is found incidentally...
October 2015: Journal of Korean Neurosurgical Society
B S Sumana, M Sabaretnam, Vijaya Sarathi, Akshatha Savith
We discuss a case of primary hyperparathyroidism caused by a giant cystic parathyroid adenoma presenting with neck swelling and hypercalcemic crisis. Fine-needle aspiration cytology of presumed thyroid swelling from one of the two sites aspirated yielded clear fluid but was not attributed to parathyroid pathology. Elevated serum calcium and intact parathormone (iPTH) levels suggested preoperative parathyroid pathology. Ultrasound neck and sestamibi scan for parathyroid localization were not conclusive. Due to resistant hypercalcemia, the patient underwent emergency bilateral neck exploration and excision of the identified left superior parathyroid cyst along with total thyroidectomy...
October 2015: Indian Journal of Pathology & Microbiology
Dhalapathy Sadacharan, Anjali Sathya, Divya Ravikumar, Deepakala Nallapa
We present a case of an 8-year-old girl with a painless swelling in her neck. An ultrasonogram revealed a cystic nodule with internal echoes, lying posterior to right lobe of thyroid, and MRI confirmed it. Thyroid scintigraphy did not show any uptake in the swelling. Intraoperatively, the lesion was densely adherent to the thyroid gland, hence a hemithyroidectomy was performed. Histopathology showed it to be an ectopic cervical thymic cyst with parathyroid tissue.
2015: BMJ Case Reports
Pauline Go, Jenna Watson, Zhichun Lu, Arthur Carlin, Zane Hammoud
Mediastinal parathyroid cysts (PC) are rare, benign lesions, reported in fewer than 150 cases worldwide. Although most are asymptomatic and discovered incidentally on imaging, symptoms of dyspnea, dysphagia, hoarseness, palpitations, hypercalcemia, and innominate or jugular venous thrombosis have been reported. Sternotomy or thoracotomy has traditionally been the approach used to resect mediastinal PCs. We describe the first reported case of a robot-assisted resection of a mediastinal PC.
September 9, 2015: General Thoracic and Cardiovascular Surgery
Jacobien C Verhave, Anneke P Bech, Jack F M Wetzels, Tom Nijenhuis
Hepatocyte nuclear factor 1β (HNF1β)-associated disease is a recently recognized clinical entity with a variable multisystem phenotype. Early reports described an association between HNF1B mutations and maturity-onset diabetes of the young. These patients often presented with renal cysts and renal function decline that preceded the diabetes, hence it was initially referred to as renal cysts and diabetes syndrome. However, it is now evident that many more symptoms occur, and diabetes and renal cysts are not always present...
February 2016: Journal of the American Society of Nephrology: JASN
Robert W Bastian, James P Thomas
OBJECTIVES: Assess the correlation between self-rating scales of talkativeness and loudness with various types of voice disorders. DESIGN: This is a retrospective study. METHODS: A total of 974 patients were analyzed. The cohort study included 430 consecutive patients presenting to the senior author with voice complaints from December 1995 to December 1998. The case-control study added 544 consecutive patients referred to the same examiner from January 1988 to December 1998 for vocal fold examination before thyroid, parathyroid, and carotid surgery...
September 2016: Journal of Voice: Official Journal of the Voice Foundation
Isaac Seow-En, Amos Hong Pheng Loh, Derrick Wen Quan Lian, Shireen Anne Nah
A 15-year old boy presented with a 2-year history of a painless slowly enlarging submental neck mass. Head and neck imaging showed a multicystic mass with a central solid component that was closely applied to the hyoid bone. Core needle biopsy under general anaesthesia revealed a papillary thyroid neoplasm. The mass was resected and frozen section histology confirmed papillary carcinoma. Intraoperatively, enlarged cervical lymph nodes were palpable. Bilateral neck dissections and total thyroidectomy with parathyroid reimplantation were performed...
2015: BMJ Case Reports
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