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Brain Benign Tumors

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https://www.readbyqxmd.com/read/28936429/clinical-pet-mri-in-neurooncology-opportunities-and-challenges-from-a-single-institution-perspective
#1
REVIEW
Lisbeth Marner, Otto M Henriksen, Michael Lundemann, Vibeke Andrée Larsen, Ian Law
PURPOSE: Magnetic resonance imaging (MRI) plays a key role in neurooncology, i.e., for diagnosis, treatment evaluation and detection of recurrence. However, standard MRI cannot always separate malignant tissue from other pathologies or treatment-induced changes. Advanced MRI techniques such as diffusion-weighted imaging, perfusion imaging and spectroscopy show promising results in discriminating malignant from benign lesions. Further, supplemental imaging with amino acid positron emission tomography (PET) has been shown to increase accuracy significantly and is used routinely at an increasing number of sites...
2017: Clinical and Translational Imaging: Reviews in Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/28932944/-cognitive-deficits-following-brain-tumor-radiation-therapy
#2
REVIEW
M Buthut, R Haussmann, A Seidlitz, M Krause, M Donix
Brain radiation is an important treatment option for malignant and benign brain diseases. The possible acute or chronic impact of radiation therapy on cognitive performance is important for daily functioning and quality of life. A detailed evaluation of cognitive impairment is important in the context of how to control disease progression. The susceptibility of the hippocampus to radiation-induced neuronal damage and its important role in memory highlight that therapeutic strategies require precision medicine...
September 20, 2017: Der Nervenarzt
https://www.readbyqxmd.com/read/28924548/remodeling-the-blood-brain-barrier-microenvironment-by-natural-products-for-brain-tumor-therapy
#3
REVIEW
Xiao Zhao, Rujing Chen, Mei Liu, Jianfang Feng, Jun Chen, Kaili Hu
Brain tumor incidence shows an upward trend in recent years; brain tumors account for 5% of adult tumors, while in children, this figure has increased to 70%. Moreover, 20%-30% of malignant tumors will eventually metastasize into the brain. Both benign and malignant tumors can cause an increase in intracranial pressure and brain tissue compression, leading to central nervous system (CNS) damage which endangers the patients' lives. Despite the many approaches to treating brain tumors and the progress that has been made, only modest gains in survival time of brain tumor patients have been achieved...
September 2017: Acta Pharmaceutica Sinica. B
https://www.readbyqxmd.com/read/28884561/tanycytic-ependymoma-of-the-brain-stem-presentations-of-rare-cystic-disease-variants-and-review-of-literature
#4
Ekkehard M Kasper, Franziska M Ippen, Georgios A Maragkos, Matthew P Anderson, Rafael Rojas, Anand Mahadevan
BACKGROUND: Tanycytic ependymoma is a rare variant of ependymoma and management guidelines for patients with this disease are not established. METHODS: We performed a systematic search on Pubmed complimented by hand- searching citation lists to identify patients with pathologically confirmed tanycytic ependymoma. Signs and symptoms, radiological and specific pathological findings as well as reported treatment modalities and outcomes were recorded and analyzed. RESULTS: 51 studies involving a total of 77 patients were identified and included in this review...
September 7, 2017: Journal of Neurosurgical Sciences
https://www.readbyqxmd.com/read/28883682/role-of-mri-in-diagnosis-of-ruptured-intracranial-dermoid-cyst
#5
Sefedin Muçaj, Mehmet Sahin Ugurel, Kreshnike Dedushi, Naser Ramadani, Naim Jerliu
INTRODUCTION: Intracranial dermoid cystic tumors account for <1% of all intracranial masses. CASE REPORT: A 52-year-old male, having headaches, nausea and is presented with a history of 2 episodes of new onset seizures. On presentation, the patient had a normal physical exam, including a complete neurological and cranial nerve exam. METHODS: Precontrast MRI; TSE/T2Wsequence in axial/coronal planes; 3D - HI-resolution T1W sagittal; FLAIR/T2W axial; FLAIR/T2W, Flash/T2W oblique coronal plane, GRE/T2W axial...
June 2017: Acta Informatica Medica: AIM
https://www.readbyqxmd.com/read/28862247/ectopic-adrenocorticotropic-hormone-syndrome-in-a-case-of-duodenal-neuroendocrine-tumor-presenting-with-liver-metastasis
#6
J Khare, S Daga, S Nalla, P Deb
Ectopic adrenocorticotropic hormone (ACTH) syndrome is an uncommon disorder and comprises about 15% of all patients with Cushing's syndrome (CS). Duodenal carcinoids are rare, indolent tumors usually associated with a benign progression. We hereby report a rare case of CS resulting from ectopic ACTH secretion from a duodenal neuroendocrine tumor (NET) presenting with liver metastasis. A 37-year-old female presented with abdominal discomfort and dyspepsia of 1-month duration. Ultrasound abdomen suggested a well-defined hypoechoic lesion in the left lobe of the liver, suggestive of neoplasia...
August 31, 2017: Journal of Postgraduate Medicine
https://www.readbyqxmd.com/read/28844928/angiomatous-meningioma-have-a-very-benign-outcome-despite-frequent-peritumoral-edema-at-onset
#7
Lingyang Hua, Shihai Luan, Haixia Li, Hongda Zhu, Hailiang Tang, Hanqiu Liu, Xiancheng Chen, Oliver Bozinov, Qing Xie, Ye Gong
OBJECTIVE: Angiomatous meningioma (AM) is a rare subtype of meningioma characterized by highly vascular tumor tissue comprised predominantly of variable sized hyalinized blood vessels. The aim is to evaluate the clinical, radiological features of AM and the long term prognosis in a single neurosurgical center. METHODS: A total of 93 patients underwent surgical resection of AMs between 2003 to 2008 were enrolled for analysis. Clinical information, treatment and radiological images were collected and analyzed; follow-up was carried out as well...
August 24, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28840085/-pure-suprasellar-schwannoma-presented-with-communicating-hydrocephalus-a-case-report
#8
Tomoya Oishi, Seiya Takehara, Yasuhiro Yamamura, Mamoru Tomida, Shinji Ito, Ken Kuriki, Hiroki Namba
Schwannoma is a benign peripheral nerve sheath tumor originating from Schwann cells. Most intracranial schwannomas arise from vestibular nerve and schwannoma in the suprasellar region is extremely rare. A 64-year-old man presented with walking disturbance and blurred vision for three months. Lateral hemianopsia in the left eye and brachybasia were observed. Magnetic resonance imaging revealed a suprasellar tumor with strong contrast enhancement associated with communicating hydrocephalus. The cerebrospinal fluid tap test improved gait disturbance...
July 2017: NMC Case Rep J
https://www.readbyqxmd.com/read/28834810/braf-v600e-mutations-occur-in-a-subset-of-glomus-tumors-and-are-associated-with-malignant-histologic-characteristics
#9
Nooshin Karamzadeh Dashti, Armita Bahrami, Seung J Lee, Sarah M Jenkins, Fausto J Rodriguez, Andrew L Folpe, Jennifer M Boland
Glomus tumors are rare mesenchymal neoplasms with a phenotype akin to the modified smooth muscle cells of the glomus body. Most are benign, but rare examples show malignant histologic characteristics and aggressive behavior. We recently encountered a malignant glomus tumor with BRAF V600E mutation. We sought to study a large cohort for this mutation, with particular attention to associated malignant histologic characteristics. Tumors were classified based on WHO criteria as benign, uncertain malignant potential (glomus tumors of uncertain malignant potential-GT-UMP), or malignant...
August 22, 2017: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28833600/clinicopathologic-features-and-pathogenesis-of-melanocytic-colonization-in-atypical-meningioma
#10
Mitra Dehghan Harati, Andrew Yu, Shino D Magaki, Mari Perez-Rosendahl, Kyuseok Im, Young K Park, Marvin Bergsneider, William H Yong
Only two prior cases of benign dendritic melanocytes colonizing a meningioma have been reported. We add a third case, describe clinicopathologic features shared by the three, and elucidate the risk factors for this very rare phenomenon. A 29 year-old Hispanic woman presented with headache and hydrocephalus. MRI showed a lobulated enhancing pineal region mass measuring 41 mm in greatest dimension. Subtotal resection of the mass demonstrated an atypical meningioma, WHO grade II, and the patient subsequently underwent radiotherapy...
August 18, 2017: Neuropathology: Official Journal of the Japanese Society of Neuropathology
https://www.readbyqxmd.com/read/28832891/outcome-of-cancer-related-seizures-in-patients-treated-with-lacosamide
#11
M Toledo, A Molins, M Quintana, E Santamarina, F Martinez-Ricarte, E Martínez-Saez, J Salas-Puig
OBJECTIVES: Lacosamide is an antiepileptic drug (AED), which has proven to be effective to control seizures, including acute conditions such as status epilepticus. The aim of this study is to describe the clinical experience with lacosamide in neuro-oncological patients. MATERIALS AND METHODS: Multicenter retrospective study in patients with cancer-related seizures, who received lacosamide as an add-on therapy. RESULTS: Forty-eight patients with benign and malignant tumors, including primary brain tumors, lymphomas, systemic cancer with central nervous system involvement, or paraneoplastic encephalitis, were included...
August 22, 2017: Acta Neurologica Scandinavica
https://www.readbyqxmd.com/read/28829874/stereotactic-radiotherapy-is-superior-for-benign-brain-tumors
#12
Anita Slomski
No abstract text is available yet for this article.
August 22, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/28812110/-extra-axial-tumors-of-the-central-nervous-system
#13
REVIEW
R Mühl-Benninghaus
Extra-axial tumors are intracranial neoplasms but are not located within the brain parenchyma. The localization of intracranial neoplasms helps to narrow down the possible differential diagnoses and also plays a deciding role in the treatment strategy and the prognosis. For this reason exact localization of these lesions is extremely important. Extra-axial tumors are the most common neoplasms among adults. They can be divided in a broad spectrum of histopathological subgroups. The most common extra-axial tumors are meningiomas, which arise from the dura mater...
August 15, 2017: Der Radiologe
https://www.readbyqxmd.com/read/28781923/discrepancy-between-radiological-and-histological-findings-in-ganglioglioma-of-the-optic-chasm-case-report
#14
Yoshito Sugita, Masahiro Sawada, Toshihiro Munemitsu, Tatsuya Higashi, Masato Hojo
BACKGROUND: Gangliogliomas involving the optic nerve or chiasm are extremely rare tumors, which can be confused radiologically with other neoplasms. α-[N-methyl-(11)C]-methylaminoisobutyric acid ((11)C-MeAIB) is a new artificial amino acid positron emission tomography (PET) tracer, which is metabolically more stable in vivo and may be more specific for tumors than (11)C-methionine. However, the utility of (11)C-MeAIB PET in the diagnosis of brain tumors has not yet been reported. CASE DESCRIPTION: A 26-year-old man presented with visual field defects and headache, and magnetic resonance imaging demonstrated a suprasellar mass involving the optic chiasm...
2017: Surgical Neurology International
https://www.readbyqxmd.com/read/28781917/long-term-recurrence-of-dysembryoplastic-neuroepithelial-tumor-clinical-case-report
#15
Daniel A Tonetti, William J Ares, R Mark Richardson, Ronald L Hamilton, Frank S Lieberman
BACKGROUND: Dysembryoplastic neuroepithelial tumors (DNETs) are rare, benign brain neoplasms that typically arise in children and adolescents and classically present with intractable, partial complex seizures. DNETs are classically associated with a favorable prognosis after complete surgical resection. CASE DESCRIPTION: We describe a case of long-term recurrence of a DNET, which initially resected and diagnosed as an oligodendroglioma prior to the recognition of DNETs...
2017: Surgical Neurology International
https://www.readbyqxmd.com/read/28746941/occurrence-of-cranial-neoplasms-in-pediatric-patients-with-noonan-syndrome-receiving-growth-hormone-is-screening-with-brain-mri-prior-to-initiation-of-growth-hormone-indicated
#16
Kanthi Bangalore Krishna, Pedro Pagan, Oscar Escobar, Jadranka Popovic
Noonan syndrome (NS) is associated with short stature. Growth hormone treatment has been FDA approved for use in these patients. Children with NS are at a higher risk of developing benign and malignant proliferative disorders, primary brain tumors being one of them. Since growth hormone therapy can worsen the tumor burden, screening with a brain MRI prior to growth hormone initiation in NS patients is strongly recommended. Here we present two NS patients who developed different primary brain tumors while being on growth hormone therapy...
July 26, 2017: Hormone Research in Pædiatrics
https://www.readbyqxmd.com/read/28735437/prospective-and-retrospective-study-of-videoconference-telemedicine-follow-up-after-elective-neurosurgery-results-of-a-pilot-program
#17
Melissa Reider-Demer, Pushpa Raja, Neil Martin, Mariel Schwinger, Diana Babayan
Existing literature suggests that use of telemedicine during postoperative appointments can increase access to care and is valued by patients and providers alike. While research examining the clinical equivalency of telemedicine visits for postoperative care has been growing, few studies have reported on telemedicine follow-up after neurosurgery. This study examined if a videoconferencing visit could substitute for an in-person clinic visit for elective neurosurgical cases in the USA. This was a single-center prospective study of patients who underwent elective neurosurgical procedures (aneurysm clipping, resection of cavernous angiomas, resection of arterial venous malformation, microvascular decompression for trigeminal neuralgia and hemifacial spasm, and certain benign brain tumors) and were offered telemedicine follow-up care by an allied health professional during the first 90 days after neurosurgery...
July 22, 2017: Neurosurgical Review
https://www.readbyqxmd.com/read/28709401/signal-transducer-and-activator-of-transcription-3-stat3-promoter-methylation-and-expression-in-pituitary-adenoma
#18
Indre Valiulyte, Giedrius Steponaitis, Daina Skiriute, Arimantas Tamasauskas, Paulina Vaitkiene
BACKGROUND: Pituitary adenoma (PA) is a benign brain tumor that can cause neurological, endocrinological and ophthalmological aberrations. Till now there is a need to identify factors that can influence the tumor invasiveness and recurrence. The aim of this study was to evaluate the associations between the signal transducer and activator of transcription 3 (STAT3) promoter methylation, mRNA expression and the invasiveness or recurrence of PAs and patient clinical characteristics. METHODS: Study participants comprised of 102 subjects with a diagnosis of PA: 54 functioning and 48 non-functioning, 58 invasive and 30 non-invasive PAs and 14 relapses...
July 14, 2017: BMC Medical Genetics
https://www.readbyqxmd.com/read/28705817/multinodular-and-vacuolating-neuronal-tumor-of-the-cerebrum-a-new-leave-me-alone-lesion-with-a-characteristic-imaging-pattern
#19
R H Nunes, C C Hsu, A J da Rocha, L L F do Amaral, L F S Godoy, T W Watkins, V H Marussi, M Warmuth-Metz, H C Alves, F G Goncalves, B K Kleinschmidt-DeMasters, A G Osborn
Multinodular and vacuolating neuronal tumor of the cerebrum is a recently reported benign, mixed glial neuronal lesion that is included in the 2016 updated World Health Organization classification of brain neoplasms as a unique cytoarchitectural pattern of gangliocytoma. We report 33 cases of presumed multinodular and vacuolating neuronal tumor of the cerebrum that exhibit a remarkably similar pattern of imaging findings consisting of a subcortical cluster of nodular lesions located on the inner surface of an otherwise normal-appearing cortex, principally within the deep cortical ribbon and superficial subcortical white matter, which is hyperintense on FLAIR...
July 13, 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/28670184/unusual-asymptomatic-fluorodeoxyglucose-avid-pheochromocytoma-in-a-case-of-myxoid-liposarcoma-of-the-extremity-on-18-f-fluorodeoxyglucose-positron-emission-tomography-computed-tomography
#20
Divya Shivdasani, Natasha Singh, Melvika Pereira, Anand Zade
Sarcomas are a heterogeneous group of rare tumors and arise either from soft tissue or from bone. Soft-tissue sarcomas (STSs) initially metastasize to the lungs. Metastases to extrapulmonary sites such as liver, brain, and soft tissue distant from primary tumor usually develop later. However, cases with isolated adrenal metastasis without disseminated disease have been reported in literature. We present a case of primary myxoid liposarcoma of the lower limb, in which staging (18)-F fluorodeoxyglucose positron emission tomography-computed tomography (FDG PET-CT) scan detected a suspicious FDG avid adrenal lesion which eventually on resection was diagnosed as asymptomatic pheochromocytoma...
July 2017: World Journal of Nuclear Medicine
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