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https://www.readbyqxmd.com/read/29040879/influence-of-sexual-behavior-of-dorper-rams-treated-with-glutamate-and-or-testosterone-on-reproductive-performance-of-anovulatory-ewes
#1
Guadalupe Calderón-Leyva, Cesar A Meza-Herrera, Rafael Martinez-Rodriguez, Oscar Angel-García, Raymundo Rivas-Muñoz, Juan V Delgado-Bermejo, Francisco G Véliz-Deras
The aim of this study was to determine if exogenous administration of glutamate and (or) testosterone to male rams during the season of reproductive arrest is able to re-activate male sexual behavior and, later on, to promote through the male effect, both sexual and reproductive competence of anovulatory nulliparous ewes. Therefore, an experiment was performed under long-day photoperiods (spring; photo-reproductive arrest, 26°N). Dorper rams were randomly divided into four homogeneous experimental groups (n = 5 males each) regarding live weight (LW), body condition score (BCS), scrotal circumference (SC) and odor intensity (OI)...
October 9, 2017: Theriogenology
https://www.readbyqxmd.com/read/29037707/predominant-yeasts-in-chinese-traditional-sourdough-and-their-influence-on-aroma-formation-in-chinese-steamed-bread
#2
Tongjie Liu, Yang Li, Faizan A Sadiq, Huanyi Yang, Jingsi Gu, Lei Yuan, Yuan Kun Lee, Guoqing He
A total of 105 yeast isolates was obtained from 15 sourdough samples collected from different regions in China and subjected to random amplified polymorphic DNA (RAPD) analysis. Six species were identified including Pichia membranifaciens, which has not previously been reported in Chinese sourdoughs. Different species of yeast were used in single-culture fermentation to make Chinese steamed bread (CSB). The volatiles of the CSB were captured by solid-phase microextraction method, separated and identified by gas chromatography-mass spectrometry...
March 1, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29031832/initial-brain-aging-heterogeneity-of-mitochondrial-size-is-associated-with-decline-in-complex-i-linked-respiration-in-cortex-and-hippocampus
#3
Kirsten Thomsen, Takashi Yokota, Md Mahdi Hasan-Olive, Niloofar Sherazi, Nima Borhan Fakouri, Claus Desler, Christine Elisabeth Regnell, Steen Larsen, Lene Juel Rasmussen, Flemming Dela, Linda Hildegard Bergersen, Martin Lauritzen
Brain aging is accompanied by declining mitochondrial respiration. We hypothesized that mitochondrial morphology and dynamics would reflect this decline. Using hippocampus and frontal cortex of a segmental progeroid mouse model lacking Cockayne syndrome protein B (CSB(m/m)) and C57Bl/6 (WT) controls and comparing young (2-5 months) to middle-aged mice (13-14 months), we found that complex I-linked state 3 respiration (CI) was reduced at middle age in CSB(m/m) hippocampus, but not in CSB(m/m) cortex or WT brain...
August 12, 2017: Neurobiology of Aging
https://www.readbyqxmd.com/read/29026502/sexual-risk-behaviors-and-condom-use-barriers-in-iranian-men-with-substance-use-disorders
#4
Effat Sadat Merghati-Khoei, Zahed Rezaei, Davood Shojaei-Zadeh, Nammam Ali Azadi, Shahnaz Rimaz, Alireza Bayat, Saeedeh Moayedi-Nia, Sanaz Omati, Farahnaz Salimi, Jeffrey Korte, Therese Killeen, Minoo Mohraz
BACKGROUND: We aimed to investigate risky sexual behaviors (RSBs) and condom use barriers in Iranian men with substance use disorders (SUDs). METHODS: Of the total 1800 outpatient drug free (ODF) and methadone maintenance treatment program (MMTP) active centers in Tehran, Iran, six were selected to participate in the current study. Data were collected (n = 300 men) using three questionnaires including a demographic questionnaire, the Risky Sexual Behavior Questionnaire (RSBQ), and the Condom Barriers Scale (CBS)...
January 2017: Addiction & Health
https://www.readbyqxmd.com/read/28934497/systematic-analysis-of-dna-crosslink-repair-pathways-during-development-and-aging-in-caenorhabditis-elegans
#5
David M Wilson, Matthias Rieckher, Ashley B Williams, Björn Schumacher
DNA interstrand crosslinks (ICLs) are generated by endogenous sources and chemotherapeutics, and pose a threat to genome stability and cell survival. Using Caenorhabditis elegans mutants, we identify DNA repair factors that protect against the genotoxicity of ICLs generated by trioxsalen/ultraviolet A (TMP/UVA) during development and aging. Mutations in nucleotide excision repair (NER) components (e.g. XPA-1 and XPF-1) imparted extreme sensitivity to TMP/UVA relative to wild-type animals, manifested as developmental arrest, defects in adult tissue morphology and functionality, and shortened lifespan...
September 19, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/28921842/anchorquery-rapid-online-virtual-screening-for-small-molecule-protein-protein-interaction-inhibitors
#6
David R Koes, Alexander Dömling, Carlos J Camacho
AnchorQuery ( http://anchorquery.csb.pitt.edu) is a web application for rational structure-based design of protein-protein interaction (PPI) inhibitors. A specialized variant of pharmacophore search is used to rapidly screen libraries consisting of more than 31 million synthesizable compounds biased by design to preferentially target PPIs. Every library compound is accessible through one-step multi-component reaction (MCR) chemistry and contains an anchor motif that is bioisosteric to an amino acid residue...
September 16, 2017: Protein Science: a Publication of the Protein Society
https://www.readbyqxmd.com/read/28900080/-dynamics-of-line-1-retrotransposon-methylation-levels-in-circulating-dna-from-lung-cancer-patients-undergoing-antitumor-therapy
#7
A A Ponomaryova, N V Cherdyntseva, A A Bondar, A Y Dobrodeev, A A Zavyalov, S A Tuzikov, V V Vlassov, E L Choinzonov, P P Laktionov, E Y Rykova
Malignant cell transformation is accompanied with abnormal DNA methylation, such as the hypermethylation of certain gene promoters and hypomethylation of retrotransposons. In particular, the hypomethylation of the human-specific family of LINE-1 retrotransposons was observed in lung cancer tissues. It is also known that the circulating DNA (cirDNA) of blood plasma and cell-surface-bound circulating DNA (csb-cirDNA) of cancer patients accumulate tumor-specific aberrantly methylated DNA fragments, which are currently considered to be valuable cancer markers...
July 2017: Molekuliarnaia Biologiia
https://www.readbyqxmd.com/read/28899434/effective-delivery-of-social-and-behavior-change-communication-through-a-care-group-model-in-a-supplementary-feeding-program
#8
Lauren Wilner, Devika J Suri, Breanne K Langlois, Shelley Marcus Walton, Beatrice Lorge Rogers
BACKGROUND: In 2014, an intervention aimed at increasing the oil in corn soy blend (CSB) porridge prepared by caregivers of children with moderate acute malnutrition was implemented in Southern Malawi. This analysis describes the flow of key messages delivered through the Care Group model during this intervention. METHODS: The intervention provided a supplementary food ration of CSB and oil and used a Care Group model in which healthcare workers were trained to deliver social and behavior change communication (SBCC) to care group volunteers who then delivered messages to caregivers of beneficiary children...
September 12, 2017: Journal of Health, Population, and Nutrition
https://www.readbyqxmd.com/read/28892496/effectiveness-of-food-supplements-in-increasing-fat-free-tissue-accretion-in-children-with-moderate-acute-malnutrition-a-randomised-2-%C3%A3-2-%C3%A3-3-factorial-trial-in-burkina-faso
#9
RANDOMIZED CONTROLLED TRIAL
Christian Fabiansen, Charles W Yaméogo, Ann-Sophie Iuel-Brockdorf, Bernardette Cichon, Maren J H Rytter, Anura Kurpad, Jonathan C Wells, Christian Ritz, Per Ashorn, Suzanne Filteau, André Briend, Susan Shepherd, Vibeke B Christensen, Kim F Michaelsen, Henrik Friis
BACKGROUND: Children with moderate acute malnutrition (MAM) are treated with lipid-based nutrient supplement (LNS) or corn-soy blend (CSB). We assessed the effectiveness of (a) matrix, i.e., LNS or CSB, (b) soy quality, i.e., soy isolate (SI) or dehulled soy (DS), and (c) percentage of total protein from dry skimmed milk, i.e., 0%, 20%, or 50%, in increasing fat-free tissue accretion. METHODS AND FINDINGS: Between September 9, 2013, and August 29, 2014, a randomised 2 × 2 × 3 factorial trial recruited 6- to 23-month-old children with MAM in Burkina Faso...
September 2017: PLoS Medicine
https://www.readbyqxmd.com/read/28793991/trial-of-ready-to-use-supplemental-food-and-corn-soy-blend-in-pregnant-malawian-women-with-moderate-malnutrition-a-randomized-controlled-clinical-trial
#10
Meghan Callaghan-Gillespie, Andrew A Schaffner, Patsy Garcia, Jocelyn Fry, Rachael Eckert, Shirin Malek, Indi Trehan, Chrissie Thakwalakwa, Kenneth M Maleta, Mark J Manary, Peggy C Papathakis
Background: Malnutrition during pregnancy in sub-Saharan Africa is associated with poor birth outcomes.Objective: This study compared maternal and offspring anthropometry for moderately malnourished pregnant women receiving ready-to-use supplemental food (RUSF), a fortified corn-soy blend (CSB+) with a daily multiple micronutrient antenatal supplement [United Nations International Multiple Micronutrient Preparation (UNIMMAP)], or standard of care comprising CSB+ and iron and folic acid (IFA).Design: A single-blind randomized controlled clinical trial was conducted in southern Malawi among 1828 pregnant women with moderate malnutrition, defined as a midupper arm circumference (MUAC) ≥20...
August 9, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28766903/multimodal-analysis-of-in-vivo-resorbable-cap-bone-substitutes-by-combining-histology-sem-and-microcomputed-tomography-data
#11
Ahmed Sweedy, Marc Bohner, Gamal Baroud
This study introduced and demonstrated a new method to investigate the repair process of bone defects using micro- and macroporous beta-tricalcium phosphate (β-TCP) substitutes. Specifically, the new method combined and aligned histology, SEM, and preimplantation microcomputed tomography (mCT) data to accurately characterize tissue phases found in biopsies, and thus better understand the bone repair process. The results included (a) the exact fraction of ceramic remnants (CR); (b) the fraction of ceramic resorbed and substituted by bone (CSB); and (c) the fraction of ceramic resorbed and not substituted by bone (CNSB)...
August 2, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/28756720/exploration-of-mtdna-control-region-sequences-in-chinese-tibetan-mastiffs
#12
Yin-Xia Li, Yi-Long Gao, Xing-Liang He, Shao-Xian Cao
The control region of mitochondrial DNA (mtDNA) was obtained from 40 purebred Chinese Tibetan Mastiffs (TMs). Sequence structure and genetic diversity were analyzed, and a phylogenetic tree was constructed. The TM mtDNA control region was composed of ETAS (extended termination associated sequences), CD (a central domain) and CSBs (conserved sequenced blocks) and sequence length showed some diversity, which was mainly caused by the number of 10 nucleotide repeat units [5'-GTA CAC GT (G/A) C-3'] between CSB I and CSB II, which ranged from 27 to 35 among individuals...
July 29, 2017: Mitochondrial DNA. Part A. DNA Mapping, Sequencing, and Analysis
https://www.readbyqxmd.com/read/28753374/continuous-symmetry-breaking-in-1d-long-range-interacting-quantum-systems
#13
Mohammad F Maghrebi, Zhe-Xuan Gong, Alexey V Gorshkov
Continuous symmetry breaking (CSB) in low-dimensional systems, forbidden by the Mermin-Wagner theorem for short-range interactions, may take place in the presence of slowly decaying long-range interactions. Nevertheless, there is no stringent bound on how slowly interactions should decay to give rise to CSB in 1D quantum systems at zero temperature. Here, we study a long-range interacting spin chain with U(1) symmetry and power-law interactions V(r)∼1/r^{α}. Using a number of analytical and numerical techniques, we find CSB for α smaller than a critical exponent α_{c}(≤3) that depends on the microscopic parameters of the model...
July 14, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28727063/effect-of-dietary-fiber-and-diet-particle-size-on-nutrient-digestibility-and-gastrointestinal-secretory-function-in-growing-pigs
#14
M Saqui-Salces, Z Luo, P E Urriola, B J Kerr, G C Shurson
Reduction of diet particle size (PS) increases feed efficiency due to an increase in the apparent total tract (ATTD) of GE. However, other effects of PS on the gut secretory function are not known. Therefore, the objective of this experiment was to measure the effect of diet composition (DC) and PS on nutrient digestibility, gastrointestinal hormones, total bile acids (TBA), total cholesterol and glucose concentrations in plasma of finishing pigs ( = 8/diet). Pigs were fed finely (374 ± 29 µm) or coarsely (631 ± 35 µm) ground corn-soybean meal (CSB), CSB + 35% corn dried distillers' grains with solubles (DDGS), and CSB with 21% soybean hulls (SBH) diets for 49 d...
June 2017: Journal of Animal Science
https://www.readbyqxmd.com/read/28711619/adsorption-of-pb-ii-ions-from-aqueous-environment-using-eco-friendly-chitosan-schiff-s-base-fe3o4-csb-fe3o4-as-an-adsorbent-kinetics-isotherm-and-thermodynamic-studies
#15
Zhang Weijiang, Zhang Yace, Gutha Yuvaraja, Xu Jiao
Chitosan and its derivatives can be used to modify magnetic materials to promote the adsorption properties of the magnetic materials for the removal of meal ions. In this study a novel CSB@Fe3O4 was prepared, characterized by XRD, FTIR, SEM, TEM, and VSM analysis and utilized as an adsorbent material for the removal of Pb(II) ions from aqueous solution. Batch studies were performed to evaluate the influences of various experimental parameters like pH, adsorbent dosage, contact time, initial concentration, and the effect of temperature...
July 12, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28707579/the-involvement-of-ercc2-xpd-and-ercc6-csb-wild-type-alleles-in-protection-against-aging-and-cancer
#16
Natalia Savina, Natalia Nikitchenko, Tatyana Kuzhir, Alexander Rolevich, Sergei Krasny, Roza Goncharova
BACKGROUND: DNA helicases maintain genome stability, and their deficiency is associated with disorders resembling premature aging as well as contributes to carcinogenesis. Their functions are determined by the respective genes encoding nucleotide excision repair initiating proteins, e.g. XPD and CSB. OBJECTIVE: The present study aimed to investigate the influence of genetic variations in ERCC2/XPD (rs1799793, rs13181) and ERCC6/CSB (rs2228526, rs2228528) loci on lifespan and developing age-related bladder cancer focusing on homozygous wild type alleles...
July 7, 2017: Current Aging Science
https://www.readbyqxmd.com/read/28666631/biochar-from-green-waste-for-phosphate-removal-with-subsequent-disposal
#17
Dhanuskodi Krishna Veni, Pandian Kannan, Thomas Nesakumar Jebakumar Immanuel Edison, Annamalai Senthilkumar
Biochar prepared from cotton stalk solid waste provides a new material for contaminant removal. In the present study, experiments were conducted to investigate the removal of phosphate from aqueous solution by cotton stalk biochar (CSB). The characterization of CSB & phosphate adsorbed biochar (PCSB) were done to substantiate the adsorption of phosphate on CSB surface. FT-IR studies disclosed the functional groups present in CSB and supported adsorption phenomena. Scanning electron microscope showed the porous nature of CSB and EDS measurements justified the phosphate adsorption process...
June 27, 2017: Waste Management
https://www.readbyqxmd.com/read/28662047/mdd-palm-identification-of-protein-s-palmitoylation-sites-with-substrate-motifs-based-on-maximal-dependence-decomposition
#18
Shun-Long Weng, Hui-Ju Kao, Chien-Hsun Huang, Tzong-Yi Lee
S-palmitoylation, the covalent attachment of 16-carbon palmitic acids to a cysteine residue via a thioester linkage, is an important reversible lipid modification that plays a regulatory role in a variety of physiological and biological processes. As the number of experimentally identified S-palmitoylated peptides increases, it is imperative to investigate substrate motifs to facilitate the study of protein S-palmitoylation. Based on 710 non-homologous S-palmitoylation sites obtained from published databases and the literature, we carried out a bioinformatics investigation of S-palmitoylation sites based on amino acid composition...
2017: PloS One
https://www.readbyqxmd.com/read/28652570/effects-of-epigallocatechin-3-gallate-egcg-on-the-bond-strength-of-fiber-posts-to-sodium-hypochlorite-naocl-treated-intraradicular-dentin
#19
Hao-Han Yu, Ling Zhang, Shuai Xu, Fang Li, Fan Yu, Zheng-Ya Liu, Li Huang, Ji-Hua Chen
This study was to evaluate the effect of Epigallocatechin-3-gallate (EGCG) on the bond strength of two adhesive systems to the Sodium hypochlorite (NaOCl) treated intraradicular dentin. The roots were accepted regular root canal treatments and post space preparations, and further divided into eight groups according to the four post space pretreatments and two dentin adhesives [Single Bond 2 (SB2) and Clearfil SE Bond (CSB)] used. The push-out strength before and after thermocycling in different root region (coronal and apical), DC of the adhesive and morphologic patterns of treated post space were evaluated...
June 26, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28630695/newly-formulated-protein-quality-enhanced-extruded-sorghum-cowpea-corn-soya-sugar-and-oil-containing-fortified-blended-foods-lead-to-adequate-vitamin-a-and-iron-outcomes-and-improved-growth-compared-with-non-extruded-csb-in-rats
#20
Nicole M Delimont, Nicole M Fiorentino, Alexander B Opoku-Acheampong, Michael V Joseph, Qingbin Guo, Sajid Alavi, Brian L Lindshield
Corn and soyabean micronutrient-fortified-blended foods (FBF) are commonly used for food aid. Sorghum and cowpeas have been suggested as alternative commodities because they are drought tolerant, can be grown in many localities, and are not genetically modified. Change in formulation of blends may improve protein quality, vitamin A and Fe availability of FBF. The primary objective of this study was to compare protein efficiency, Fe and vitamin A availability of newly formulated extruded sorghum-, cowpea-, soya- and corn-based FBF, along with a current, non-extruded United States Agency for International Development (USAID) corn and soya blend FBF (CSB+)...
2017: Journal of Nutritional Science
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