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JOURNAL ARTICLE
D Ioannides, N Antonakopoulos, V Chasapi, C Oikonomou, E Tampouratzi, E Lazaridou, D Rigopoulos, O Neofotistou, A Drosos, G Anastasiadis, E Rovithi, C Kalinou, E Papadavid, P Aronis, M Papageorgiou, A Protopapa, I Bassukas, I Lefaki, E Zafiriou, K Krasagakis, E Pokas, Z Anagnostopoulos, A Kekki, M Papakonstantis
BACKGROUND: Real-world data in patients with moderate psoriasis treated with apremilast is limited. OBJECTIVES: To evaluate the effectiveness and safety of apremilast in bio-naïve patients with moderate psoriasis in real-world clinical settings. METHODS: This was a 52-week multicenter, observational, prospective study of adult outpatients with moderate psoriasis {[10%<body surface area<20% or 10<psoriasis area severity index (PASI)<20] and 10<dermatology quality of life index (DLQI)<20} initiated on apremilast ≤7 days before enrollment...
April 22, 2022: Journal of the European Academy of Dermatology and Venereology: JEADV
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JOURNAL ARTICLE
Jean-Luc Brun, Loïc Sentilhes, Antoine Torre, Cyrille Huchon, Charles Garabedian, Guillaume Legendre, Jeanne Sibiude, Marie-Victoire Sénat, Henri Marret, Thomas Schmitz
OBJECTIVES: To evaluate the revision of methodology of the clinical practice guidelines (CPG) of the French National College of Gynecologists and Obstetricians (CNGOF). METHOD: Three CPGs were organized in 2020 on the topics of severe preeclampsia, menorrhagia, and prophylactic surgery according to AGREE II (Apraisal of Guidelines for Research & Evaluation). Questions were presented in PICO (Population, Intervention, Comparison, Outcome) format and the grading of scientific evidence was based on the GRADE (Grading of Recommendation Assessment, Development and Evaluation) method...
November 18, 2021: Gynecologie, Obstetrique, Fertilite & Senologie
#3
REVIEW
Panagiota Lafiatoglou, Caroline Ellis-Hill, Mary Gouva, Avraam Ploumis, Stefanos Mantzoukas
AIMS: To acquire an in-depth understanding of how older individuals diagnosed with acquired brain injury (ABI) experience their well-being and care when undergoing physical rehabilitation. DESIGN: Systematic literature review. DATA SOURCES: The electronic databases of PubMed, CINAHL, APA PsycInfo, ASSIA and SCOPUS were searched from 2005 to 2020. Extensive reference checking was also conducted. REVIEW METHODS: A systematic review was conducted following PRISMA guidelines, including predominantly qualitative studies...
August 16, 2021: Journal of Advanced Nursing
#4
JOURNAL ARTICLE
D Ioannides, N Antonakopoulos, S Georgiou, V Chasapi, I Katsantonis, A Drosos, D Rigopoulos, C Antoniou, G Anastasiadis, I Bassukas, D Ioannidou, A Protopapa, O Neofotistou, K Krasagakis, P Aronis, M Papageorgiou, E Lazaridou, A Patsatsi, I Lefaki, A V Roussaki-Schulze, F Satra, Z Anagnostopoulos, M Papakonstantis
BACKGROUND: Apremilast is an oral phosphodiesterase-4 inhibitor indicated for patients with moderate-to-severe chronic plaque psoriasis and active psoriatic arthritis. OBJECTIVES: To examine the effectiveness of apremilast on Dermatology Life Quality Index (DLQI), Psoriasis Area and Severity Index (PASI) and nail, scalp and palmoplantar involvement, when administered prior to biologics. METHODS: This 52-week real-world study included biologic-naive adults with moderate psoriasis (psoriasis-involved body surface area 10% to <20%, or PASI 10 to <20 and DLQI 10 to <20)...
September 2021: Journal of the European Academy of Dermatology and Venereology: JEADV
#5
JOURNAL ARTICLE
Anna Lovatt, Oliver Mason, Caroline Brett, Emmanuelle Peters
This study examined some of the predictions made by cognitive models of psychosis, specifically the potential contribution of appraisals and trauma to the development of "need for care." Two groups reporting psychotic-like experiences with and without a "need for care" were compared on types of experiences, appraisals of these experiences, distress, and trauma. Both groups reported similar overall levels of psychotic-like experiences, but were characterized by distinct types of experiences. The clinical group was more distressed, endorsed more externalizing and personalizing appraisals, and fewer psychological/normalizing apraisals of their experiences than the nonclinical group...
November 2010: Journal of Nervous and Mental Disease
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JOURNAL ARTICLE
Gilles Breuzard, Jean-Marc Millot, Jean-François Riou, Michel Manfait
Complexes formed between G-quadruplex (G4)-conformed oligonucleotides and four ethidium derivatives were studied by surface-enhanced Raman spectroscopy (SERS) to detail the topology of complexes that support a G4 stabilization. Ethidium bromide (EB), which presents a weak ability to stabilize oligonucleotides in G4 conformation, displayed no SERS intensity modification when bound to G4, as compared with the free EB. Three ethidium derivatives have been selected due to their higher ability to stabilize G4 than EB...
August 15, 2003: Analytical Chemistry
#7
JOURNAL ARTICLE
R BERNARD, M SANSOT, R JAUBERT, P DAVID
No abstract text is available yet for this article.
1962: Pédiatrie
#8
JOURNAL ARTICLE
W Seger
The sociomedical statements given on the basis of Sociomedical Clinic apraisement of 103 patients were compared with those rendered at discharge from previous in-patient rehabilitation. Discrepant judgements and evaluation problems in describing functional capacity at work are pointed out, and their causes discussed. Proposals are submitted for enhancing more effective cooperation between rehabilitation clinics and the Sociomedical Services of the pension insurance administrations.
February 1993: Die Rehabilitation
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JOURNAL ARTICLE
M Lequesne, J Lamotte, M Samson
The main Indices of Quality of Life used in rheumatology and their aims and applications are surveyed. Their use in osteoarthritis implies a few issues that are addressed in a critical manner. Indices of Quality of Life are useful to measure deficiency resulting from osteoarthritis by comparison with other rheumatic diseases, as rheumatoid arthritis, connective tissue diseases, fibromyalgia... They are sensitive enough for apraising the domains improved by a radical treatment such as joint replacement. However, their scores are only slightly changing in most of the drug trials, in which the more simple functional indices seem demonstrative enough...
May 1993: Revue du Rhumatisme: Maladies des Os et des Articulations
#10
JOURNAL ARTICLE
S G Ball, D M Chalmers, A G Morgan, A J Solman, M S Losowsky
No abstract text is available yet for this article.
July 1973: Biomedicine / [publiée Pour L'A.A.I.C.I.G.]
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JOURNAL ARTICLE
P F Urban, H Dreyfus, N Virmaux, G Franck
No abstract text is available yet for this article.
October 1972: Journal de Physiologie
#12
JOURNAL ARTICLE
V I Ul'ianov
No abstract text is available yet for this article.
April 1978: Khirurgiia
#13
REVIEW
An apraisal of the role of aldosterone and the sympathetic nervous system in essential hypertension.
J Rosenthal
Of the various hypertensive disorders in which mineralocorticoid hormones are involved mainly those are reviewed in which, apart from aldosterone, hyporeactivity of the adrenergic nervous system may play a permissive role. The simultaneous occurrence and extent of participation of these two factors in essential hypertension are being appreciated increasingly. Their share in the mosaic of hypertension may add to the accumulating knowledge of this disease entity. In exploring the underlying mechanisms of hypertension common regulatory pathways involving aldosterone and the adrenergic nervous system may lead to new aethiopathogenetic insights...
June 1979: Hormone and Metabolic Research
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JOURNAL ARTICLE
N Ghilezan, N Milea, S Tamburlini
Cobaltotherapy was applied in 194 cases of bronchopulmonary cancer in the Oncologic Institute of Cluj-Napoca, during the 1967--1974 period. The mean survial was of 15 months, the results being influenced by the histologic type and locoregional extent apraised on the basis of the TNM classification proposed by the American Joint Committe for Cancer Staging and End Result Reporting. The mean survival after irradiation was of 9.7% and 5.1% at 3 and 5 years respectively. Standardization of the cases according to the TNM criteria showed the advanced stage of the patients referred for radiotherapy, proving a useful tool for establishing the prognosis and therapeutical indications...
April 1977: Revista de Igienă, Bacteriologie, Virusologie, Parazitologie, Epidemiologie, Pneumoftiziologie. Pneumoftiziologia
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