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https://www.readbyqxmd.com/read/28834530/treating-delayed-sleep-wake-phase-disorder-in-young-adults
#1
Diane B Boivin
No abstract text is available yet for this article.
September 2017: Journal of Psychiatry & Neuroscience: JPN
https://www.readbyqxmd.com/read/28822033/clinical-and-polysomnographic-characteristics-of-excessive-daytime-sleepiness-in-children
#2
Jiwon Lee, Geonyoub Na, Eun Yeon Joo, Munhyang Lee, Jeehun Lee
PURPOSE: This study aimed to delineate the clinical and polysomnography (PSG) characteristics of sleep disorders in children with excessive daytime sleepiness (EDS). METHODS: Between February 2002 and June 2015, 622 pediatric patients with EDS were evaluated with overnight PSG and the Multiple Sleep Latency Test at the Samsung Medical Center. The medical records; questionnaire responses about depression, sleepiness, sleep habits; and sleep study data of 133 patients without obstructive sleep apnea (OSA) were reviewed retrospectively...
August 18, 2017: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/28777179/comorbid-sleep-disturbances-in-neurologic-disorders
#3
Yo-El S Ju, Aleksandar Videnovic, Bradley V Vaughn
PURPOSE OF REVIEW: This article provides a review of disturbances of sleep comorbid with common neurologic disorders. RECENT FINDINGS: A wide variety of neurologic disorders are frequently complicated by comorbid sleep disturbances. In many cases, a bidirectional relationship appears to occur between sleep function and the neurologic disease, such that treatment of comorbid sleep disturbances may improve the symptoms of the neurologic disease. SUMMARY: Neurologic disorders are often associated with abnormalities of sleep...
August 2017: Continuum: Lifelong Learning in Neurology
https://www.readbyqxmd.com/read/28777176/circadian-rhythm-sleep-wake-disorders
#4
Milena Pavlova
PURPOSE OF REVIEW: The endogenous circadian rhythms are one of the cardinal processes that control sleep. They are self-sustaining biological rhythms with a periodicity of approximately 24 hours that may be entrained by external zeitgebers (German for time givers), such as light, exercise, and meal times. This article discusses the physiology of the circadian rhythms, their relationship to neurologic disease, and the presentation and treatment of circadian rhythm sleep-wake disorders...
August 2017: Continuum: Lifelong Learning in Neurology
https://www.readbyqxmd.com/read/28774755/human-seasonal-and-circadian-studies-in-antarctica-halley-75%C3%A2-s
#5
Josephine Arendt, Benita Middleton
Living for extended periods in Antarctica exposes base personnel to extremes of daylength (photoperiod) and temperature. At the British Antarctic Survey base of Halley, 75°S, the sun does not rise for 110d in the winter and does not set for 100d in summer. Photoperiod is the major time cue governing the timing of seasonal events such as reproduction in many species. The neuroendocrine signal providing photoperiodic information to body physiology is the duration of melatonin secretion which reflects the length of the night: longer in the short days of winter and shorter in summer...
August 1, 2017: General and Comparative Endocrinology
https://www.readbyqxmd.com/read/28771555/neonates-responses-to-repeated-exposure-to-a-still-face
#6
Emese Nagy, Karen Pilling, Rachel Watt, Attila Pal, Hajnalka Orvos
AIM: The main aims of the study were to examine whether human neonates' responses to communication disturbance modelled by the still-face paradigm were stable and whether their responses were affected by their previous experience with the still-face paradigm. METHODS: The still face procedure, as a laboratory model of interpersonal stress, was administered repeatedly, twice, to 84 neonates (0 to 4 day olds), with a delay of an average of 1.25 day. RESULTS: Frame-by-frame analysis of the frequency and duration of gaze, distressed face, crying, sleeping and sucking behaviours showed that the procedure was stressful to them both times, that is, the still face effect was stable after repeated administration and newborns consistently responded to such nonverbal violation of communication...
2017: PloS One
https://www.readbyqxmd.com/read/28713258/relationship-of-topology-multiscale-phase-synchronization-and-state-transitions-in-human-brain-networks
#7
Minkyung Kim, Seunghwan Kim, George A Mashour, UnCheol Lee
How the brain reconstitutes consciousness and cognition after a major perturbation like general anesthesia is an important question with significant neuroscientific and clinical implications. Recent empirical studies in animals and humans suggest that the recovery of consciousness after anesthesia is not random but ordered. Emergence patterns have been classified as progressive and abrupt transitions from anesthesia to consciousness, with associated differences in duration and electroencephalogram (EEG) properties...
2017: Frontiers in Computational Neuroscience
https://www.readbyqxmd.com/read/28711776/sleep-wake-profiles-and-circadian-rhythms-of-core-temperature-and-melatonin-in-young-people-with-affective-disorders
#8
Joanne S Carpenter, Rébecca Robillard, Daniel F Hermens, Sharon L Naismith, Christopher Gordon, Elizabeth M Scott, Ian B Hickie
While disturbances of the sleep-wake cycle are common in people with affective disorders, the characteristics of these disturbances differ greatly between individuals. This heterogeneity is likely to reflect multiple underlying pathophysiologies, with different perturbations in circadian systems contributing to the variation in sleep-wake cycle disturbances. Such disturbances may be particularly relevant in adolescents and young adults with affective disorders as circadian rhythms undergo considerable change during this key developmental period...
July 8, 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/28707143/clinical-sleep-wake-disorders-ii-focus-on-insomnia-and-circadian-rhythm-sleep-disorders
#9
Kai Spiegelhalder, Christoph Nissen, Dieter Riemann
Insomnia and circadian rhythm sleep disorders affect large proportions of the population and have pronounced effects on quality of life and daytime performance. While the neurobiology of insomnia is not yet fully understood, circadian rhythm sleep disorders are assumed to be caused by a mismatch between the individual circadian phase position and the desired sleep-wake schedule. Benzodiazepines and non-benzodiazepine positive allosteric GABAA receptor modulators improve sleep onset and maintenance in the short-term treatment of insomnia...
July 14, 2017: Handbook of Experimental Pharmacology
https://www.readbyqxmd.com/read/28651468/human-adolescent-phase-response-curves-to-bright-white-light
#10
Stephanie J Crowley, Charmane I Eastman
Older adolescents are particularly vulnerable to circadian misalignment and sleep restriction, primarily due to early school start times. Light can shift the circadian system and could help attenuate circadian misalignment; however, a phase response curve (PRC) to determine the optimal time for receiving light and avoiding light is not available for adolescents. We constructed light PRCs for late pubertal to postpubertal adolescents aged 14 to 17 years. Participants completed 2 counterbalanced 5-day laboratory sessions after 8 or 9 days of scheduled sleep at home...
August 2017: Journal of Biological Rhythms
https://www.readbyqxmd.com/read/28648359/evidence-for-the-efficacy-of-melatonin-in-the-treatment-of-primary-adult-sleep-disorders
#11
REVIEW
Fiona Auld, Emily L Maschauer, Ian Morrison, Debra J Skene, Renata L Riha
Melatonin is a physiological hormone involved in sleep timing and is currently used exogenously in the treatment of primary and secondary sleep disorders with empirical evidence of efficacy, but very little evidence from randomised, controlled studies. The aim of this meta-analysis was to assess the evidence base for the therapeutic effects of exogenous melatonin in treating primary sleep disorders. An electronic literature review search of MEDLINE (1950-present) Embase (1980- present), PsycINFO (1987- present), and Scopus (1990- present), along with a hand-searching of key journals was performed in July 2013 and then again in May 2015...
July 20, 2016: Sleep Medicine Reviews
https://www.readbyqxmd.com/read/28643991/sleep-duration-quality-of-life-and-depression-in-adolescents-a-school-based-survey
#12
Chantal Stheneur, Marc Sznajder, Camille Spiry, Marianna Marcu Marin, Idir Ghout, Patricia Samb, Grégoire Benoist
BACKGROUND: The main objective of this study was to assess the link between sleep duration, quality of life and depression in adolescents. The secondary objective was to study the sleeping behavior of a large sample of adolescents from different socioeconomic backgrounds. METHODS: Study subjects were high school students studying in or around Paris with a general, vocational or technological training background. A survey was conducted to evaluate the subject's perception of their own sleep, quality of life and depression...
June 22, 2017: Minerva Pediatrica
https://www.readbyqxmd.com/read/28621018/sleep-structure-in-blindness-is-influenced-by-circadian-desynchrony
#13
Sébrina Aubin, Poul Jennum, Tore Nielsen, Ron Kupers, Maurice Ptito
We examined the structure, duration and quality of sleep, including non-rapid eye movement sleep and rapid eye movement sleep, in 11 blind individuals without conscious light perception and 11 age- and sex-matched sighted controls. Because blindness is associated with a greater incidence of free-running circadian rhythms, we controlled for circadian phase by a measure of melatonin onset timing. When circadian rhythm was entrained and melatonin onset occurred at normal times, sleep structure did not differ between blind and sighted individuals...
June 16, 2017: Journal of Sleep Research
https://www.readbyqxmd.com/read/28607474/irregular-sleep-wake-patterns-are-associated-with-poorer-academic-performance-and-delayed-circadian-and-sleep-wake-timing
#14
Andrew J K Phillips, William M Clerx, Conor S O'Brien, Akane Sano, Laura K Barger, Rosalind W Picard, Steven W Lockley, Elizabeth B Klerman, Charles A Czeisler
The association of irregular sleep schedules with circadian timing and academic performance has not been systematically examined. We studied 61 undergraduates for 30 days using sleep diaries, and quantified sleep regularity using a novel metric, the sleep regularity index (SRI). In the most and least regular quintiles, circadian phase and light exposure were assessed using salivary dim-light melatonin onset (DLMO) and wrist-worn photometry, respectively. DLMO occurred later (00:08 ± 1:54 vs. 21:32 ± 1:48; p < 0...
June 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28584667/melatonin-secretion-pattern-in-critically-ill-patients-a-pilot-descriptive-study
#15
Yuliya Boyko, René Holst, Poul Jennum, Helle Oerding, Miki Nikolic, Palle Toft
Critically ill patients have abnormal circadian and sleep homeostasis. This may be associated with higher morbidity and mortality. The aims of this pilot study were (1) to describe melatonin secretion in conscious critically ill mechanically ventilated patients and (2) to describe whether melatonin secretion and sleep patterns differed in these patients with and without remifentanil infusion. Eight patients were included. Blood-melatonin was taken every 4th hour, and polysomnography was carried out continually during a 48-hour period...
2017: Critical Care Research and Practice
https://www.readbyqxmd.com/read/28569119/skin-temperature-rhythms-in-humans-respond-to-changes-in-the-timing-of-sleep-and-light
#16
Marc Cuesta, Philippe Boudreau, Nicolas Cermakian, Diane B Boivin
Body temperature is known to vary with circadian phase and to be influenced by factors that can mask its circadian expression. We wanted to test whether skin temperature rhythms were sensitive to an abrupt shift of the sleep schedule and to the resetting effects of light. Nineteen healthy subjects spent 6 days in time isolation and underwent a simulated night-shift procedure. They were assigned to either a control group ( n = 10) or bright light group ( n = 9) and measurements were taken under a baseline day-oriented schedule and during the 4(th) cycle of a night-oriented schedule...
June 2017: Journal of Biological Rhythms
https://www.readbyqxmd.com/read/28553739/anatomical-and-behavioral-investigation-of-c1ql3-in-the-mouse-suprachiasmatic-nucleus
#17
Kylie S Chew, Diego C Fernandez, Samer Hattar, Thomas C Südhof, David C Martinelli
Many biochemical, physiological, and behavioral processes such as glucose metabolism, body temperature, and sleep-wake cycles show regular daily rhythms. These circadian rhythms are adjusted to the environmental light-dark cycle by a central pacemaker located in the suprachiasmatic nucleus (SCN) in order for the processes to occur at appropriate times of day. Here, we investigated the expression and function of a synaptic organizing protein, C1QL3, in the SCN. We found that C1ql3 is robustly expressed in the SCN...
June 2017: Journal of Biological Rhythms
https://www.readbyqxmd.com/read/28526480/human-seasonal-and-circadian-studies-in-antarctica-halley-75-0-s
#18
Josephine Arendt, Benita Middleton
Living for extended periods in Antarctica exposes base personnel to extremes of daylength (photoperiod) and temperature. At the British Antarctic Survey base of Halley, 75(0)S, the sun does not rise for 110 d in the winter and does not set for 100 d in summer. Photoperiod is the major time cue governing the timing of seasonal events such as reproduction in many species. The neuroendocrine signal providing photoperiodic information to body physiology is the duration of melatonin secretion which reflects the length of the night: longer in the short days of winter and shorter in summer...
May 16, 2017: General and Comparative Endocrinology
https://www.readbyqxmd.com/read/28522096/sleep-and-circadian-variability-in-people-with-delayed-sleep-wake-phase-disorder-versus-healthy-controls
#19
Helen J Burgess, Margaret Park, James K Wyatt, Muneer Rizvydeen, Louis F Fogg
OBJECTIVE/BACKGROUND: To compare sleep and circadian variability in adults with delayed sleep-wake phase disorder (DSWPD) to healthy controls. PATIENTS/METHODS: Forty participants (22 DSWPD, 18 healthy controls) completed a ten-day protocol, consisting of DLMO assessments on two consecutive nights, a five-day study break, followed by two more DLMO assessments. All participants were instructed to sleep within one hour of their self-reported average sleep schedule for the last four days of the study break...
June 2017: Sleep Medicine
https://www.readbyqxmd.com/read/28522084/circadian-phase-dynamics-of-subjective-sleepiness-and-sensitivity-to-blue-light-in-young-adults-complaining-of-a-delayed-sleep-schedule
#20
Christophe Moderie, Solenne Van der Maren, Marie Dumont
OBJECTIVE: To assess factors that might contribute to a delayed sleep schedule in young adults with sub-clinical features of delayed sleep phase disorder. METHODS: Two groups of 14 young adults (eight women) were compared: one group complaining of a delayed sleep schedule and a control group with an earlier bedtime and no complaint. For one week, each subject maintained a target bedtime reflecting their habitual sleep schedule. Subjects were then admitted to the laboratory for the assessment of circadian phase (dim light melatonin onset), subjective sleepiness, and non-visual light sensitivity...
June 2017: Sleep Medicine
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