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https://www.readbyqxmd.com/read/28329741/drugs-violence-and-trauma-in-m%C3%A3-xico-and-united-states
#1
Juan Carlos Puyana, Juan Carlos Jacob Puyana, Andres Mariano Rubiano, Jorge Hernan Montenegro, Glyn O Estebanez, Alvaro Ignacio Sanchez, Felipe Vega-Rivera
The impact of illicit drug markets on the occurrence of violence varies tremendously depending on many factors. Over the last years, Mexico and United States (US) has increased security border issues that included many aspects of drug-related trade and criminal activities. Mexico experienced only a small reduction of trauma deaths after severe crime reinforcement policies. This strategy in the war on drugs is shifting the drug market to other Central American countries. This phenomenon is called the ballooning effect where by pressure to control illicit drug related activities in one particular area forces a shift to other more vulnerable areas that lead to increase crime and violence...
March 21, 2017: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
https://www.readbyqxmd.com/read/28329261/effects-of-noise-on-vascular-function-oxidative-stress-and-inflammation-mechanistic-insight-from-studies-in-mice
#2
Thomas Münzel, Andreas Daiber, Sebastian Steven, Lan P Tran, Elisabeth Ullmann, Sabine Kossmann, Frank P Schmidt, Matthias Oelze, Ning Xia, Huige Li, Antonio Pinto, Philipp Wild, Kai Pies, Erwin R Schmidt, Steffen Rapp, Swenja Kröller-Schön
Aims: Epidemiological studies indicate that traffic noise increases the incidence of coronary artery disease, hypertension and stroke. The underlying mechanisms remain largely unknown. Field studies with nighttime noise exposure demonstrate that aircraft noise leads to vascular dysfunction, which is markedly improved by vitamin C, suggesting a key role of oxidative stress in causing this phenomenon. Methods and results: We developed a novel animal model to study the vascular consequences of aircraft noise exposure...
February 17, 2017: European Heart Journal
https://www.readbyqxmd.com/read/28328677/genitourinary-injuries-following-traffic-accidents-analysis-of-a-registry-of-162-690-victims
#3
Jean E Terrier, P Paparel, B Gadegbeku, Alain Ruffion, Lawrence C Jenkins, Amina N'Diaye
BACKGROUND: Traffic accidents are the most frequent cause of genitourinary injuries (GUI). Kidney injuries following trauma have been well described. However, there exists a paucity of data on other traumatic genitourinary injuries following traffic accidents. The objective of this study was to analyze the frequency and type of all genitourinary injuries, by user category, following traffic accidents. METHODS: Patient cases were extracted from the trauma registry of the French department of Rhone from 1996 to 2013...
March 21, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28327843/-geographic-information-systems
#4
Akram Hernández-Vásquez, Diego Azañedo, Guido Bendezú-Quispe, Josmel Pacheco-Mendoza, R Martín Chaparro
The aim of this study was to geospatially explore the occurrence rates of car accidents involving pedestrians in Cercado de Lima (Lima District), Peru. Car accidents involving pedestrians recorded in the 2015 National Police Station Census of the National Statistics and Information Institute were described and georeferenced. Subsequently, a Kernel Density analysis was carried out to locate areas with high, medium, and low density events. Records of 171 car accidents involving pedestrians were studied: the types of vehicles involved were automobiles (56...
October 2016: Revista Peruana de Medicina Experimental y Salud Pública
https://www.readbyqxmd.com/read/28327086/design-of-the-lifestyle-interventions-for-severe-mentally-ill-outpatients-in-the-netherlands-lion-trial-a-cluster-randomised-controlled-study-of-a-multidimensional-web-tool-intervention-to-improve-cardiometabolic-health-in-patients-with-severe-mental-illness
#5
Anne Looijmans, Frederike Jörg, Richard Bruggeman, Robert Schoevers, Eva Corpeleijn
BACKGROUND: The cardiometabolic health of persons with a severe mental illness (SMI) is alarming with obesity rates of 45-55% and diabetes type 2 rates of 10-15%. Unhealthy lifestyle behaviours play a large role in this. Despite the multidisciplinary guideline for SMI patients recommending to monitor and address patients' lifestyle, most mental health care professionals have limited lifestyle-related knowledge and skills, and (lifestyle) treatment protocols are lacking. Evidence-based practical lifestyle tools may support both patients and staff in improving patients' lifestyle...
March 21, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28326809/identifying-factors-affecting-the-safety-of-mid-block-bicycle-lanes-considering-mixed-two-wheeled-traffic-flow
#6
Lu Bai, Ching-Yao Chan, Pan Liu, Chengcheng Xu
OBJECTIVE: Electric bikes (e-bikes) were one of the fastest growing trip modes in Southeast Asia over the past two decades. The increasing popularity of e-bikes raised some safety concerns on urban transport system. The primary objective of this study was to identify whether and how the generalized linear regression model (GLM) could be used to relate the cyclists' safety with various contributing factors when they were riding in a mid-block bike lane. The types of two-wheeled vehicles in the study included bicycle style electric bicycles (BSEBs), scooter style electric bicycles (SSEBs) and regular bicycles (RBs)...
March 22, 2017: Traffic Injury Prevention
https://www.readbyqxmd.com/read/28326768/air-pollution-and-climate-change-effects-on-allergies-in-the-anthropocene-abundance-interaction-and-modification-of-allergens-and-adjuvants
#7
Kathrin Reinmuth-Selzle, Christopher J Kampf, Kurt Lucas, Naama Lang-Yona, Janine Fröhlich-Nowoisky, Manabu Shiraiwa, Pascale Sylvie Jeanne Lakey, Senchao Lai, Fobang Liu, Anna Theresa Kunert, Kira Ziegler, Fangxia Shen, Rossella Sgarbanti, Bettina Weber, Iris Bellinghausen, Joachim Saloga, Michael G Weller, Albert Duschl, Detlef Schuppan, Ulrich Pöschl
Air pollution and climate change are potential drivers for the increasing burden of allergic diseases. The molecular mechanisms by which air pollutants and climate parameters may influence allergic diseases, however, are complex and elusive. This article provides an overview of physical, chemical and biological interactions between air pollution, climate change, allergens, adjuvants and the immune system, addressing how these interactions may promote the development of allergies. We reviewed and synthesized key findings from atmospheric, climate, and biomedical research...
March 22, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28325809/the-rab7-effector-plekhm1-binds-arl8b-to-promote-cargo-traffic-to-lysosomes
#8
Rituraj Marwaha, Subhash B Arya, Divya Jagga, Harmeet Kaur, Amit Tuli, Mahak Sharma
Endocytic, autophagic, and phagocytic vesicles move on microtubule tracks to fuse with lysosomes. Small GTPases, such as Rab7 and Arl8b, recruit their downstream effectors to mediate this transport and fusion. However, the potential cross talk between these two GTPases is unclear. Here, we show that the Rab7 effector PLEKHM1 simultaneously binds Rab7 and Arl8b, bringing about clustering and fusion of late endosomes and lysosomes. We show that the N-terminal RUN domain of PLEKHM1 is necessary and sufficient for interaction with Arl8b and its subsequent localization to lysosomes...
March 21, 2017: Journal of Cell Biology
https://www.readbyqxmd.com/read/28324995/eeg-based-mental-fatigue-detection-by-spectral-non-negative-matrix-factorization
#9
Lili Li, Guanghua Xu, Jun Xie, Min Li, Sicong Zhang, Ailing Luo
After long time cognitive work, most of people confronted with the mental fatigue, which can decrease the classification accuracy of cognitive, or even cause the traffic accidents for drivers. Therefore, the detection of the fatigue state is very essential. The study aims to explore an effective and novel approach based on electroencephalogram. All participants were instructed to implement the spelling experiments. Data were recorded on the awake condition, on sleep deprivation condition and after two hour spelling experiment...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28324824/new-algorithm-for-analyzing-phosphorescence-curves-its-application-to-the-k2yf5-pr-compound
#10
F Ortega, J Marcazzó, F Spano, M Santiago, P Molina, E Caselli
Analysis of phosphorescence curves is an alternative procedure to glow curve analysis in order to find the parameters characterizing trap and recombination centers of thermoluminescence materials. In this article a new algorithm to analyze phosphorescence curves is reported, which is derived from the set of coupled differential equation describing the carrier traffic without resorting to approximations. The new algorithm has been employed to analyze the phosphorescence curves of the K2YF5:Pr compound.
March 6, 2017: Applied Radiation and Isotopes
https://www.readbyqxmd.com/read/28324820/the-relationship-between-motorcycle-rider-behaviour-questionnaire-scores-and-crashes-for-riders-in-australia
#11
A N Stephens, J Brown, L de Rome, M R J Baldock, R Fernandes, M Fitzharris
Motorcycle riders are over-represented in road fatalities in Australia. While riders represent 18% of the road users killed each year, motorcycle registrations constitute only 4.5% of the registered vehicle fleet. The Motorcycle Rider Behaviour Questionnaire (MRBQ) was developed with a view toward understanding behaviours likely to be associated with crash risk. These include behaviours that are either intentional (such as violations of road and speed regulations and stunts) or unintentional (such as errors relating to traffic or control of the motorcycle), as well as protective behaviours related to use of safety equipment...
March 18, 2017: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/28324111/arap1-deficiency-causes-photoreceptor-degeneration-in-mice
#12
Ala Moshiri, Devin Humpal, Brian C Leonard, Denise M Imai, Addy Tham, Lynette Bower, Dave Clary, Thomas M Glaser, K C Kent Lloyd, Christopher J Murphy
Purpose: Small guanosine triphosphatase (GTPase) ADP-ribosylation factors (Arfs) regulate membrane traffic and actin reorganization under the control of GTPase-activating proteins (GAPs). Arap1 is an Arf-directed GAP that inhibits the trafficking of epidermal growth factor receptor (EGFR) to the early endosome, but the diversity of its functions is incompletely understood. The aim of this study was to determine the role of Arap1 in the mammalian retina. Methods: Genetically engineered Arap1 knockout mice were screened for ocular abnormalities in the National Institutes of Health Knockout Mouse Production and Phenotyping (KOMP2) Project...
March 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28324000/trh-action-is-impaired-in-pituitaries-of-male-igsf1-deficient-mice
#13
Marc-Olivier Turgeon, Tanya L Silander, Denica Doycheva, Xiao-Hui Liao, Marc Rigden, Luisina Ongaro, Xiang Zhou, Sjoerd D Joustra, Jan M Wit, Mike G Wade, Heike Heuer, Samuel Refetoff, Daniel J Bernard
Loss-of-function mutations in the X-linked immunoglobulin superfamily, member 1 (IGSF1) gene cause central hypothyroidism. IGSF1 is a transmembrane glycoprotein of unknown function expressed in TSH-producing thyrotrope cells of the anterior pituitary gland. The protein is co-translationally cleaved, with only its C-terminal domain (CTD) being trafficked to the plasma membrane. Most intragenic IGSF1 mutations in humans map to the CTD. Here, we used CRISPR-Cas9 to introduce a loss-of-function mutation into the IGSF1-CTD in mice...
January 13, 2017: Endocrinology
https://www.readbyqxmd.com/read/28323434/development-of-potential-methods-for-testing-congestion-control-algorithm-implemented-in-vehicle-to-vehicle-communications
#14
Chung-Jen Hsu, Joshua Fikentscher, Robert Kreeb
Objective A channel congestion problem might occur when the traffic density increases since the number of basic safety messages carried on the communication channel also increases in vehicle-to-vehicle communications. A remedy algorithm proposed in SAE J2945/1 is designed to address the channel congestion issue by decreasing transmission frequency and radiated power. This study is to develop potential test procedures for evaluating or validating the congestion control algorithm. Methods Simulations of a reference unit transmitting at a higher frequency are implemented to emulate a number of Onboard Equipment (OBE) transmitting at the normal interval of 100 milliseconds (10 Hz)...
March 21, 2017: Traffic Injury Prevention
https://www.readbyqxmd.com/read/28322446/increased-long-term-risk-of-hearing-loss-in-patients-with-traumatic-brain-injury-a-nationwide-population-based-study
#15
Wei-Chuan Shangkuan, Hung-Che Lin, Cheng-Ping Shih, Chun-An Cheng, Hueng-Chuen Fan, Chi-Hsiang Chung, Fu-Huang Lin, Chang-Huei Tsao, Wu-Chien Chien
OBJECTIVES/HYPOTHESIS: We investigated incidences of hearing loss among patients with traumatic brain injury (TBI) to evaluate whether they had a higher risk of hearing loss than the general population. STUDY DESIGN: Cohort study. METHODS: Inpatient data from the Taiwan National Health Insurance Research Database from January 1, 2000 to December 31, 2010 were recorded. Patients with TBI and a retrospective comparison cohort were analyzed. Each subject was individually traced from their index date to identify subjects who subsequently received a diagnosis of hearing loss...
March 21, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28321937/ultrafine-particles-and-black-carbon-personal-exposures-in-asthmatic-and-non-asthmatic-children-at-school-age
#16
Pau Pañella, Maribel Casas, David Donaire-Gonzalez, Raquel Garcia-Esteban, Oliver Robinson, Antònia Valentín, John Gulliver, Isabelle Momas, Mark Nieuwenhuijsen, Martine Vrijheid, Jordi Sunyer
Traffic-related air pollution (TRAP) exposure during childhood is associated with asthma; however, the contribution of the different TRAP pollutants in each microenvironment (home, school, transportation, others) in asthmatic and non-asthmatic children is unknown. Daily (24 h) personal black carbon (BC), ultrafine particles (UFP), and alveolar lung deposited surface area (LDSA) individual exposure measurements were obtained from 100 children (29 past and 21 current asthmatics, 50 non-asthmatics) aged 9±0.7 years from the INMA-Sabadell cohort (Catalonia, Spain)...
March 20, 2017: Indoor Air
https://www.readbyqxmd.com/read/28321469/inter-annual-variation-of-ambient-ammonia-and-related-trace-gases-in-delhi-india
#17
S K Sharma, Saraswati, T K Mandal, Mohit Saxena
In this study, ambient NH3, NO, NO2, CO and SO2 were measured continuously from February, 2008, to December, 2016. The annual average mixing ratios (mole/mole) of NH3, NO, NO2, CO and SO2 were 17.8 ± 3.4 ppb; 21.2 ± 2.3 ppb, 18.1 ± 3.2 ppb; 1.7 ± 0.3 ppm and 2.0 ± 0.3 ppb, respectively. All the trace gases (NH3, NO, NO2, CO and SO2) showed significant annual variation during the study. A significant increasing trend in mixing ratios of ambient NH3 and NO2 were observed at the observational site of Delhi, whereas, increasing trend were recorded in case of NO, CO and NO2 mixing ratios...
March 20, 2017: Bulletin of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/28321356/island-posterior-thigh-flap-revisited-in-covering-extensive-sacral-wounds-our-experience-with-two-patients
#18
F Nangole Wanjala, Ajujo Martin
Deep sacral wounds are best covered by flaps. Posterior thigh flaps have routinely been used to cover such wounds. The flap can however be modified as an island flap. Two patients with extensive sacral wounds were managed with island posterior thigh flaps. Both patients were admitted secondary to road traffic accident with subsequent soft tissue loss of the sacral area. The sacral defects in both patients were approximately 17 cm by 23 cm in dimensions. Unilateral island posterior thigh flap was raised and used to cover the wounds...
2017: Case Reports in Surgery
https://www.readbyqxmd.com/read/28319757/interaction-driver-bicyclist-on-rural-roads-effects-of-cross-sections-and-road-geometric-elements
#19
Francesco Bella, Manuel Silvestri
The interaction of motorists and bicyclists, particularly during passing maneuvers, is cited as one of the primary causes of bicyclist fatalities. This paper reports the results of a driving simulator study, which sought to analyze the effects that three cross-section configurations of a two-lane rural road and four geometric elements of the road have on driver behavior, during the interaction with a cyclist. A two-lane rural road, about 11km long, was designed and implemented in an advanced-interactive driving simulator...
March 17, 2017: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/28319756/on-the-effect-of-networks-of-cycle-tracks-on-the-risk-of-cycling-the-case-of-seville
#20
R Marqués, V Hernández-Herrador
We analyze the evolution of the risk of cycling in Seville before and after the implementation of a network of segregated cycle tracks in the city. Specifically, we study the evolution of the risk for cyclists of being involved in a collision with a motor vehicle, using data reported by the traffic police along the period 2000-2013, i.e. seven years before and after the network was built. A sudden drop of such risk was observed after the implementation of the network of bikeways. We study, through a multilinear regression analysis, the evolution of the risk by means of explanatory variables representing changes in the built environment, specifically the length of the bikeways and a stepwise jump variable taking the values 0/1 before/after the network was implemented...
March 16, 2017: Accident; Analysis and Prevention
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