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JOURNAL ARTICLE
Nuha Alghamdi, Bhaskar Das, Santosh I Hugar, Priyanka Sarangi, Garima Garg, Savadamoorthi Kamatchi Subramani
BACKGROUND AND AIM: A sessile multicellular organism that is immersed in a self-produced matrix of extracellular polymeric substances and has its cells firmly attached to a surface is referred to as a microbial biofilm. When it comes to pulp and periradicular pathosis, biofilms are crucial. To reduce the number of microorganisms in the root canal and assist in treating periapical pathosis, endodontic therapy must include decontamination of the system of tooth root canals through biomechanical preparation and irrigation of the root canal...
January 2024: Curēus
#22
REVIEW
Erica Almeida Carvalho Peixoto, Vanessa de Brito Poveda, Juliana Rizzo Gnatta, Ramon Antonio Oliveira
BACKGROUND: Recommendations for different types of bathing to prevent central line-associated bloodstream infections (CLABSI) are still divergent. The objective of this study was to verify whether bed bathing with wipes impregnated with 2% chlorhexidine (CHG) compared to conventional bed bathing is more effective in preventing CLABSI. METHODS: Systematic review of the literature by consulting the electronic databases PubMed/Medline, Embase, CINAHL, Scopus, and Web of Science from the date of inception until July 1, 2023, with no language or time restrictions...
February 10, 2024: American Journal of Infection Control
#23
JOURNAL ARTICLE
Tayyaba Zeeshan, Zeeshan Qamar, Nishath Sayed Abdul, Cristalle Soman, Badr Bamousa, Maria Maddalena Marrapodi, Marco Cicciù, Giuseppe Minervini
BACKGROUND: Commercially available oral rinses contain active ingredients with concentration that is claimed by manufacturers to be effective as antiplaque agent. To date there has been no mention of the effect of oral rinse on the adherence of early plaque colonizers in plaque formation and the concentration to be used before/after meals. OBJECTIVE: The chief aim of the study was to evaluate microbial retention on the salivary pellicle on treatment with oral rinses (CHX & EO)/PS (mimicking after meals use of mouth wash/PS)...
January 23, 2024: Technology and Health Care: Official Journal of the European Society for Engineering and Medicine
#24
JOURNAL ARTICLE
Ahmed Shawky Ammar, Hossam Elnoamany, Hany Elkholy
BACKGROUND: In pediatrics, shunt infection is considered the most common complication of ventriculoperitoneal (VP) shunts insertion and the main cause of shunt failure. Careful surgical technique and hygienic skin preparations are highly important for prevention of shunt infections. Our objective was to assess the significance of using preoperative chlorhexidine/alcohol as a skin antiseptic in reducing the infection rate in pediatric VP shunts surgery. PATIENTS AND METHODS: A retrospective, case control study conducted on 80 pediatric patients with active hydrocephalus...
February 9, 2024: Journal of Neurological Surgery. Part A, Central European Neurosurgery
#25
JOURNAL ARTICLE
Saaya Matayoshi, Fumikazu Tojo, Yuto Suehiro, Makoto Okuda, Misato Takagi, Marin Ochiai, Maika Kadono, Yusuke Mikasa, Rena Okawa, Ryota Nomura, Yoshito Itoh, Naoto Itoh, Kazuhiko Nakano
Periodontitis is known to be associated with type 2 diabetes mellitus (T2DM), and gargling with mouthwash is known to reduce the incidence of periodontitis by inhibiting periodontal pathogens. However, the effects of mouthwash on oral and systemic conditions in patients with T2DM remain unknown. In this study, we investigated the effects of gargling with mouthwash on the number of red complex species, including Porphyromonas gingivalis, Treponema denticola, and Tannerella forsythia, and HbA1c levels in patients with T2DM...
February 2, 2024: Scientific Reports
#26
RANDOMIZED CONTROLLED TRIAL
Sheila Sprague, Gerard Slobogean, Jeffrey L Wells, Nathan N O'Hara, Lehana Thabane, C Daniel Mullins, Anthony D Harris, Amber Wood, Darius Viskontas, Kelly L Apostle, Robert V O'Toole, Manjari Joshi, Herman Johal, Jamal Al-Asiri, Robert A Hymes, Greg E Gaski, Holly T Pilson, Eben A Carroll, Sharon Babcock, Jason J Halvorson, Nicholas M Romeo, Christopher A Matson, Thomas F Higgins, Lucas S Marchand, Patrick F Bergin, John Morellato, Robert E Van Demark, G David Potter, I Leah Gitajn, Gerard Chang, Kevin D Phelps, Laurence B Kempton, Madhav Karunakar, Todd Jaeblon, Haley K Demyanovich, Christopher M Domes, Gabrielle R Kuhn, Rachel M Reilly, Mark J Gage, Michael J Weaver, Arvind G von Keudell, Marilyn Heng, Michael F McTague, Ahmad Alnasser, Samir Mehta, Derek J Donegan, Roman M Natoli, Jan Szatkowski, Alesha N Scott, Steven F Shannon, Kyle J Jeray, Stephanie L Tanner, Meir T Marmor, Amir Matityahu, Justin T Fowler, Sarah N Pierrie, Michael J Beltran, Cameron G Thomson, Carol A Lin, Charles N Moon, John A Scolaro, Arya Amirhekmat, Jordan Leonard, David Pogorzelski, Sofia Bzovsky, Diane Heels-Ansdell, Olivia P Szasz, Jodi L Gallant, Gregory J Della Rocca, Robert D Zura, Joan N Hebden, Joseph T Patterson, Christopher Lee, Lyndsay M O'Hara, Debra Marvel, Jana E Palmer, Jeff Friedrich, Jean-Claude G D'Alleyrand, Jessica C Rivera, Franca Mossuto, Gregory M Schrank, Gordon Guyatt, P J Devereaux, Mohit Bhandari
BACKGROUND: Studies evaluating surgical-site infection have had conflicting results with respect to the use of alcohol solutions containing iodine povacrylex or chlorhexidine gluconate as skin antisepsis before surgery to repair a fractured limb (i.e., an extremity fracture). METHODS: In a cluster-randomized, crossover trial at 25 hospitals in the United States and Canada, we randomly assigned hospitals to use a solution of 0.7% iodine povacrylex in 74% isopropyl alcohol (iodine group) or 2% chlorhexidine gluconate in 70% isopropyl alcohol (chlorhexidine group) as preoperative antisepsis for surgical procedures to repair extremity fractures...
February 1, 2024: New England Journal of Medicine
#27
JOURNAL ARTICLE
Staci S Reynolds, Julee Waldrop
INTRODUCTION: Quantitative research and quality improvement (QI) both seek to improve care provided to patients. However, clinicians often blur the lines between how to appropriately analyze data from these methodologies. Clinicians may inappropriately use statistical analyses for QI initiatives, rather than using run and statistical process control (SPC) charts to analyze improvements in outcomes. OBJECTIVE: The purpose of this article was to address the analytic methods used for QI initiatives in the clinical setting in an effort to show clinicians how to identify meaningful improvements in clinical practice...
March 2024: Dimensions of Critical Care Nursing: DCCN
#28
JOURNAL ARTICLE
Sandra Sarembe, Nicole Michler, Carolin Ufer, Andreas Kiesow
OBJECTIVES: The study aimed to develop and test an in vitro model to investigate the staining potential of mouth rinses on human enamel, considering alternating intake of black tea and tooth brushing, thus mimicking the situation in the oral cavity more realistically. MATERIALS AND METHODS: Eight mouth rinses with six different active ingredients (benzydamine hydrochloride [BNZ], polyhexamethylene biguanide hydrochloride [PHMB], chlorhexidine digluconate [CHX], hexetidine gluconate [HEX], octenidine dihydrochloride [OCT] and octenidine dihydrochloride + 2-phenoxyethanol [OCTP]) and concentrations were tested...
January 23, 2024: European Journal of Dentistry
#29
EDITORIAL
Tzu-Fen Huang, Yu-Kai Su, I-Chang Su, Yun-Kai Yeh, Heng-Wei Liu, I-Hung Kan, Yu-Chun Lu, Yu-Pei Chang, Chien-Min Lin, Yong-Kwang Tu, Chien-Hua Tseng
BACKGROUND: External ventricular drain (EVD) is used for monitoring intracranial pressure or diverting cerebrospinal fluid. However, confirmation of an infection is not immediate and requires obtaining culture results, often leading to the excessive use of antibiotics. This study aimed to compare noninfectious ventriculitis and EVD infection in terms of the risk factors, predictors, prognosis, and effectiveness of care bundle interventions. METHODS: This retrospective study was conducted at a medical center with 1,006 beds in northern Taiwan between January 2018 and July 2022...
January 22, 2024: Neurocritical Care
#30
JOURNAL ARTICLE
José Pimenta, Carla Dias, Mário Cotovio, Maria José Saavedra
Considering the increasing antibiotics resistance, there has been a propensity to replace them with antiseptics when it comes to wound management and treatment. Nevertheless, in recent years, there have been reports regarding resistance to antiseptics by some bacterial strains. There is also concern about the environmental impact of these substances. The aim of this study was to compare the antimicrobial efficacy of antiseptics and eucalyptus essential oils on bacterial strains from horse's wounds. We used twelve Escherichia coli , eight Staphylococcus aureus , two Staphylococcus pseudintermedius , one Staphylococcus vitulinus and one Staphylococcus saprophyticus strains from equine wounds...
December 26, 2023: Veterinary Sciences
#31
JOURNAL ARTICLE
Goutham Vijayakumar, Gidean A Sundaram, Santhosh P Kumar, Vinod K Krishna, Murugesan Krishnan
Introduction Oral and maxillofacial surgeons frequently perform the removal of impacted mandibular third molars. The success of this surgical intervention depends on meticulous surgical technique and the use of appropriate irrigants to minimize complications in the postoperative period. Aim The aim of this study was to evaluate the efficacy of four different irrigation solutions (povidone-iodine, metronidazole, chlorhexidine gluconate (CHX), and normal saline) on postoperative sequelae like pain, trismus, swelling, and alveolar osteitis following surgical extraction of the impacted mandibular third molars...
December 2023: Curēus
#32
JOURNAL ARTICLE
Karthik Kannaiyan, Pinaki Rakshit, Murali Patla Shivarama Bhat, Sreelakshmy Kammath Korattiparambil Sadasiva, Sreeja Chandra Babu, Haseena Ummer
AIM: The current study aimed to determine the impact of three different disinfectants on the surface roughness and color stability of heat-cure acrylic denture material. MATERIALS AND METHODS: Using a stainless-steel mold, disc-shaped wax patterns with dimensions of 10 mm in diameter and 2 mm thick (in accordance with ADA Specification No. 12) were created and prepared for a total of 75 acrylic samples. Dimensions of all 75 acrylic samples were checked with a digital Vernier caliper...
November 1, 2023: Journal of Contemporary Dental Practice
#33
JOURNAL ARTICLE
Zilma Pereira Muneeswaran, Baran Teoman, Yu Wang, Haroon Chaudhry, Tatiana V Brinzari, Gaurav Verma, Lomaani Ranasinghe, Kylie Ryan Kaler, Xiaoyi Huang, Xing He, Belvin Thomas, Shiyou Xu, Chi-Yuan Cheng, Jeffrey M Boyd, Dailin Chen, Zhigang Hao, Shengqian Ma, Tewodros Asefa, Long Pan, Viktor Dubovoy
Chlorhexidine dodecyl sulfate (CHX-DS) was synthesized and characterized via single-crystal X-ray diffraction (SC-XRD), 1 H nuclear magnetic resonance (NMR) spectroscopy, 1 H nuclear Overhauser effect spectroscopy (NOESY), and attenuated total reflectance Fourier-transform infrared spectroscopy (ATR-FTIR). The solid-state structure, comprising a 1 : 2 stoichiometric ratio of chlorhexidine cations [C22 H30 Cl2 N10 ]2+ to dodecyl sulfate anions [C12 H25 SO4 ]- , is the first report of chlorhexidine isolated with a surfactant...
January 15, 2024: Dalton Transactions: An International Journal of Inorganic Chemistry
#34
JOURNAL ARTICLE
Stefano Restaino, Veronica Tius, Martina Arcieri, Anna Biasioli, Giulia Pellecchia, Lorenza Driul, Giuseppe Vizzielli
OBJECTIVE: To compare the amounts of water and plastic used in surgical hand washing with medicated soaps and with alcohol-based products and to compare costs and consumption in a year, based on scheduled surgical activity. METHOD: This retrospective study was carried out at Udine's Gynecology Operating Block from October to November 2022. We estimated the average amount of water with a graduated cylinder and the total cost of water usage based on euros/m3 indicated by the supplier; for each antiseptic agent we collected the data relevant to wash time, amount of water and product used per scrub, number of handscrubs made with every 500 mL bottle and cost of a single bottle...
January 11, 2024: International Journal of Gynaecology and Obstetrics
#35
JOURNAL ARTICLE
Nadia Alansari, Mushriq Abid, Arkadiusz Dziedzic
AIMS AND OBJECTIVE: Presurgical infant's orthopedic appliances (PSIOs) play an increasingly crucial role in the interdisciplinary management of neonatal CLP, aiming to improve and maintain adequate nasolabial aesthetics, followed by primary lip/nasal surgery in both unilateral and bilateral CLP cases. The use of PSIOs in cleft lip and palate patients can lead to contamination with oral microflora, acting as a potential reservoir for infectious microorganisms. Acrylic surfaces might provide retention niches for microorganisms to adhere, and inhabit, which is difficult to control in immunocompromised patients, thus predisposing them to increased infection risks...
January 2, 2024: Clinical Oral Investigations
#36
JOURNAL ARTICLE
Katelyn Gough, Tim R Dargaville, Amanda Ullman, Nicole Marsh, Elise Pelzer
BACKGROUND: Vascular access devices form an essential component in the management of acute and chronic medical conditions. Introduction and ongoing management of these devices are linked with bundles of care aimed at reducing associated risks including bleeding and infection. AIM: To evaluate the antimicrobial potential of the potassium ferrate haemostatic disc on Gram-positive (Staphylococcus aureus) and Gram-negative (Klebsiella pneumoniae, Pseudomonas aeruginosa) bacteria and on Candida albicans...
December 28, 2023: Journal of Hospital Infection
#37
JOURNAL ARTICLE
Ranj Nadhim Salaie
The biofilm formation around dental implant abutment is considered the main cause of peri-implant infection. The use of antimicrobial mouthwash might potentially reduce biofilm formation and subsequent infection. This study aimed to evaluate the antibiofilm properties of mastic gum resin extract (MGRE) against S. Mutans biofilm on the surface of titanium dental implant discs. This study used grade five (medical grade) titanium dental implant discs measuring 15 mm in diameter. The substances in the MGRE were analyzed by gas chromatography mass spectrometry (GC-MS) which found 12 detectable chemicals in MGRE...
December 10, 2023: Cellular and Molecular Biology
#38
JOURNAL ARTICLE
M Bar Ilan, S Dovrat, R Cohen, M Georgaki, E Papadopoulou, N G Nikitakis, N Yarom
OBJECTIVES: The symptoms of herpes simplex viruses type 1 (HSV-1) infections might be severe and persistent in immunocompromised patients in whom they reactivate at a high frequency. The development of Acyclovir (ACV) resistant strains due to long-term treatment with antiviral agents in those patients is not uncommon. The aim of the present study was to assess the virucidal effect of commercially available mouthwashes against ACV-resistant HSV-1 strains. MATERIALS AND METHODS: Two acyclovir-resistant HSV-1 strains were exposed for 30 s to essential oil-based (Listerine Fresh Burst® and Listerine Zero®), chlorhexidine gluconate 0...
December 27, 2023: Oral Diseases
#39
JOURNAL ARTICLE
Valerie Lapp, Bertha Ben Khallouq, Dana Bentley, Allie Kirkland, Jill Dykstra-Nykanen, Keith Ayotte
National standards for surgical site infection (SSI) prevention for children remain elusive. Our institution developed a presurgical antisepsis protocol that included the three components of chlorhexidine gluconate bathing wipes, chlorhexidine gluconate oral rinse, and povidone-iodine nasal swab. This retrospective cohort study examined data from electronic health records to compare SSI rates before and after protocol implementation. We included children aged 2 through 11 years undergoing any surgical procedure with the use of an incision in the OR (N = 1,356)...
January 2024: AORN Journal
#40
JOURNAL ARTICLE
Vanessa Marchant, Flavia Trionfetti, Lucia Tejedor-Santamaria, Sandra Rayego-Mateos, Dante Rotili, Giulio Bontempi, Alessandro Domenici, Paolo Menè, Antonello Mai, Catalina Martín-Cleary, Alberto Ortiz, Adrian M Ramos, Raffaele Strippoli, Marta Ruiz-Ortega
Peritoneal dialysis (PD) is a current replacement therapy for end-stage kidney diseases (ESKDs). However, long-term exposure to PD fluids may lead to damage of the peritoneal membrane (PM) through mechanisms involving the activation of the inflammatory response and mesothelial-to-mesenchymal transition (MMT), leading to filtration failure. Peritoneal damage depends on a complex interaction among external stimuli, intrinsic properties of the PM, and subsequent activities of the local innate-adaptive immune system...
November 29, 2023: Antioxidants (Basel, Switzerland)
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