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chlorhexidine gluconate

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https://www.readbyqxmd.com/read/29778430/does-periurethral-cleaning-with-water-prior-to-indwelling-urinary-catheterization-increase-the-risk-of-urinary-tract-infections-a-systematic-review-and-meta-analysis
#1
REVIEW
Kun Huang, Jihong Liang, Ting Mo, Yanli Zhou, Yanping Ying
OBJECTIVE: To determine whether periurethral cleaning with water before indwelling urinary catheterization increases the risk of urinary tract infections (UTIs) compared with studies using anti-infective agents. METHODS: A literature search via MEDLINE, Embase, and the Cochrane Central Register of Controlled Trials through October 2017 and a manual search of references for additional relevant studies. Trials studying clean intermittent catheterization were excluded...
May 16, 2018: American Journal of Infection Control
https://www.readbyqxmd.com/read/29766214/caution-for-chlorhexidine-gluconate-use-for-oral-care-insufficient-data
#2
EDITORIAL
Jean-Damien Ricard, Thiago Lisboa
No abstract text is available yet for this article.
May 15, 2018: Intensive Care Medicine
https://www.readbyqxmd.com/read/29761329/bactericidal-and-virucidal-activity-of-povidone-iodine-and-chlorhexidine-gluconate-cleansers-in-an-in-vivo-hand-hygiene-clinical-simulation-study
#3
Maren Eggers, Torsten Koburger-Janssen, Lois S Ward, Craig Newby, Stefan Müller
INTRODUCTION: Standard in vitro and in vivo tests help demonstrate efficacy of hand hygiene products; however, there is no standard in vivo test method for viruses. We investigated the bactericidal and virucidal efficacy of povidone-iodine (PVP-I) 7.5% scalp and skin cleanser, chlorhexidine gluconate (CHG) 4% hand cleanser and the reference hand wash (soft soap) in 15 healthy volunteers following European Standard EN1499 (hygienic hand wash test method for bacteria), which was adapted for virucidal testing...
May 14, 2018: Infectious Diseases and Therapy
https://www.readbyqxmd.com/read/29745356/noninfectious-hospital-adverse-events-decline-after-elimination-of-contact-precautions-for-mrsa-and-vre
#4
Elise M Martin, Brandy Bryant, Tristan R Grogan, Zachary A Rubin, Dana L Russell, David Elashoff, Daniel Z Uslan
OBJECTIVETo evaluate the impact of discontinuing routine contact precautions (CP) for endemic methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus (VRE) on hospital adverse events.DESIGNRetrospective, nonrandomized, observational, quasi-experimental study.SETTINGAcademic medical center with single-occupancy rooms.PARTICIPANTSInpatients.METHODSWe compared hospital reportable adverse events 1 year before and 1 year after discontinuation of routine CP for endemic MRSA and VRE (preintervention and postintervention periods, respectively)...
May 10, 2018: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/29744564/effects-of-chlorhexidine-gluconate-oral-care-on-hospital-mortality-a-hospital-wide-observational-cohort-study
#5
Mieke Deschepper, Willem Waegeman, Kristof Eeckloo, Dirk Vogelaers, Stijn Blot
PURPOSE: Chlorhexidine oral care is widely used in critically and non-critically ill hospitalized patients to maintain oral health. We investigated the effect of chlorhexidine oral care on mortality in a general hospitalized population. METHODS: In this single-center, retrospective, hospital-wide, observational cohort study we included adult hospitalized patients (2012-2014). Mortality associated with chlorhexidine oral care was assessed by logistic regression analysis...
May 9, 2018: Intensive Care Medicine
https://www.readbyqxmd.com/read/29733329/effectiveness-of-a-chlorhexidine-dressing-on-silver-coated-external-ventricular-drain-associated-colonization-infection-a-prospective-single-blinded-randomized-controlled-clinical-trial-evdai-study
#6
Michel Roethlisberger, Giusi Moffa, Urs Fisch, Benedikt Wiggli, Stephan Schoen, Christopher Kelly, Severina Leu, Davide Croci, Daniel W Zumofen, Nadine Cueni, Danica Nogarth, Marianne Schulz, Heiner C Bucher, Maja Weisser-Rohacek, Morten-Goetz Wasner, Andreas F Widmer, Luigi Mariani
Background: Observational studies have shown that dressings containing chlorhexidine gluconate (CHX) lower the incidence external ventricular drain (EVD) associated infections (EVDAI). This prospective, randomized controlled trial (RCT) studies the efficacy of CHX-containing dressings in reducing bacterial colonization, which represents an important risk factor for infectious complications. Methods: In this single-site, prospective, double-blinded RCT, patients aged ≥18 undergoing emergency EVD placement were randomly given either a CHX- or an otherwise identical control dressing at the skin exit wound of the EVD...
May 4, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29706945/-candida-auris-disinfectants-and-implications-for-infection-control
#7
REVIEW
Tsun S N Ku, Carla J Walraven, Samuel A Lee
Candida auris is a rapidly emerging pathogen and is able to cause severe infections with high mortality rates. It is frequently misidentified in most clinical laboratories, thus requiring more specialized identification techniques. Furthermore, several clinical isolates have been found to be multidrug resistant and there is evidence of nosocomial transmission in outbreak fashion. Appropriate infection control measures will play a major role in controlling the management and spread of this pathogen. Unfortunately, there are very few data available on the effectiveness of disinfectants against C...
2018: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29671041/oropharyngeal-and-nasopharyngeal-decontamination-with-chlorhexidine-gluconate-in-lung-cancer-surgery-a-randomized-clinical-trial
#8
Xavier Benoit D'Journo, Pierre-Emmanuel Falcoz, Marco Alifano, Jean-Philippe Le Rochais, Thomas D'Annoville, Gilbert Massard, Jean Francois Regnard, Philippe Icard, Charles Marty-Ane, Delphine Trousse, Christophe Doddoli, Bastien Orsini, Sophie Edouard, Matthieu Million, Nathalie Lesavre, Anderson Loundou, Karine Baumstarck, Florence Peyron, Stephane Honoré, Stéphanie Dizier, Aude Charvet, Marc Leone, Didier Raoult, Laurent Papazian, Pascal Alexandre Thomas
PURPOSE: Respiratory complications are the leading causes of morbidity and mortality after lung cancer surgery. We hypothesized that oropharyngeal and nasopharyngeal decontamination with chlorhexidine gluconate (CHG) would be an effective method to reduce these complications as reported in cardiac surgery. METHODS: In this multicenter parallel-group randomized double-blind placebo-controlled trial, we enrolled consecutive adults scheduled for anatomical pulmonary resection for lung cancer...
April 18, 2018: Intensive Care Medicine
https://www.readbyqxmd.com/read/29629331/a-scanning-electron-microscope-evaluation-of-smear-layer-removal-and-antimicrobial-action-of-mixture-of-tetracycline-acid-and-detergent-sodium-hypochlorite-ethylenediaminetetraacetic-acid-and-chlorhexidine-gluconate-an-in-vitro-study
#9
K M Charlie, M A Kuttappa, Liza George, K V Manoj, Bobby Joseph, Nishin K John
Objectives: The main objective is to evaluate the efficiency in removal of smear layer of mixture of tetracycline, acid and detergent (MTAD), sodium hypochlorite (NaOCl), ethylenediaminetetraacetic acid (EDTA) and chlorhexidine gluconate by scanning electron microscope (SEM) evaluation and also to evaluate the antimicrobial action of the same irrigants against standard culture strains of Enterococcus faecalis . Materials and Methods: This study included 60 extracted permanent teeth with single root canal...
January 2018: Journal of International Society of Preventive & Community Dentistry
https://www.readbyqxmd.com/read/29627326/one-percent-chlorhexidine-alcohol-for-preventing-central-venous-catheter-related-infection-during-intensive-chemotherapy-for-patients-with-haematologic-malignancies
#10
Shimon Ohtake, Hiromichi Takahashi, Masaru Nakagawa, Yoshihito Uchino, Katsuhiro Miura, Noriyoshi Iriyama, Tomohiro Nakayama, Yoshihiro Hatta, Masami Takei
A central venous catheter (CVC) is a catheter placed into a large vein, and is used for chemotherapy administration. However, there is little confirmatory data on which antiseptic-such as chlorhexidine or povidone-iodine (PI) -is more protective against CVC-related infectious complications in patients receiving intensive chemotherapy. We aimed to compare the effectiveness of 1% chlorhexidine gluconate in 70% alcohol (CH) vs. PI for skin disinfection before CVC insertion in patients receiving intensive chemotherapy...
April 4, 2018: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://www.readbyqxmd.com/read/29610200/efref-and-the-transcription-regulator-chlr-are-required-for-chlorhexidine-stress-response-in-enterococcus-faecalis-v583
#11
Farry J Li, Kelli L Palmer
Enterococcus faecalis is an opportunistic pathogen and leading cause of healthcare-associated infections. Daily chlorhexidine gluconate (CHG) bathing of patients is generally regarded as an effective strategy to reduce the occurrence of healthcare-associated infections. It is likely that E. faecalis are frequently exposed to inhibitory and sub-inhibitory CHG in clinical settings. The goal of this study was to investigate how the vancomycin-resistant strain E. faecalis V583 transcriptionally responds to and tolerates stress from CHG...
April 2, 2018: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/29587817/the-effect-of-chlorhexidine-on-dental-calculus-formation-an-in-vitro-study
#12
Yuuki Sakaue, Shoji Takenaka, Tatsuya Ohsumi, Hisanori Domon, Yutaka Terao, Yuichiro Noiri
BACKGROUND: Chlorhexidine gluconate (CHG) has been proven to be effective in preventing and controlling biofilm formation. At the same time, an increase in calculus formation is known as one of considerable side effects. The purpose of this study was to investigate whether mineral deposition preceding a calculus formation would occur at an early stage after the use of CHG using an in vitro saliva-related biofilm model. METHODS: Biofilms were developed on the MBEC™ device in brain heart infusion (BHI) broth containing 0...
March 27, 2018: BMC Oral Health
https://www.readbyqxmd.com/read/29580742/propionibacterium-acnes-persists-despite-various-skin-preparation-techniques
#13
Nathanael Heckmann, Lakshmanan Sivasundaram, K Soraya Heidari, Alexander E Weber, Erik N Mayer, Reza Omid, C Thomas Vangsness, George F Hatch
PURPOSE: To investigate the efficacy of various skin preparations at eradicating Propionibacterium acnes in the dermal layer of the skin. METHODS: Twelve healthy volunteers consented to participate in this study. Each subject's upper back was prepped using 4 different techniques: an isopropyl alcohol control, chlorhexidine gluconate paint, chlorhexidine gluconate plus a mechanical scrub, and a high-concentration chlorhexidine gluconate plus a mechanical scrub. A 3-mm dermal punch biopsy specimen was obtained at each preparation site...
March 23, 2018: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/29580304/impact-of-discontinuing-contact-precautions-for-methicillin-resistant-staphylococcus-aureus-and-vancomycin-resistant-enterococcus-an-interrupted-time-series-analysis
#14
Gonzalo Bearman, Salma Abbas, Nadia Masroor, Kakotan Sanogo, Ginger Vanhoozer, Kaila Cooper, Michelle Doll, Michael P Stevens, Michael B Edmond
OBJECTIVETo investigate the impact of discontinuing contact precautions among patients infected or colonized with methicillin-resistant Staphylococcus aureus (MRSA) or vancomycin-resistant Enterococcus (VRE) on rates of healthcare-associated infection (HAI). DESIGN: Single-center, quasi-experimental study conducted between 2011 and 2016.METHODSWe employed an interrupted time series design to evaluate the impact of 7 horizontal infection prevention interventions across intensive care units (ICUs) and hospital wards at an 865-bed urban, academic medical center...
June 2018: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/29520956/effect-of-chemical-disinfectants-on-the-color-stability-of-maxillofacial-silicones-an-in-vitro-study
#15
Ankita Chamaria, Meena A Aras, Vidya Chitre, Praveen Rajagopal
PURPOSE: To evaluate the effect of chemical disinfection on the color stability of room temperature vulcanizing (RTV) maxillofacial silicone elastomer with and without pigment addition. MATERIALS AND METHODS: Sixty specimens were obtained from a RTV maxillofacial silicone. The specimens were randomly divided into 6 groups according to pigments and disinfectant to be used (n = 10). NP-DW-nonpigmented silicone specimens to be immersed in distilled water (control)...
March 8, 2018: Journal of Prosthodontics: Official Journal of the American College of Prosthodontists
https://www.readbyqxmd.com/read/29519510/qac-genes-and-biocide-tolerance-in-clinical-veterinary-methicillin-resistant-and-methicillin-susceptible-staphylococcus-aureus-and-staphylococcus-pseudintermedius
#16
Kate A Worthing, Alan Marcus, Sam Abraham, Darren J Trott, Jacqueline M Norris
Qac genes are associated with increased tolerance to quaternary ammonium compounds and other cationic biocides such as chlorhexidine. This study aimed to determine whether qac genes and increased biocide tolerance were present in 125 clinical methicillin-resistant and susceptible veterinary staphylococci. A total of 125 methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-resistant and -susceptible Staphylococcus pseudintermedius (MRSP and MSSP) from three archived Australian veterinary staphylococci collections underwent whole genome sequencing, multilocus sequence typing and qac gene screening...
March 2018: Veterinary Microbiology
https://www.readbyqxmd.com/read/29493475/differential-effects-of-chlorhexidine-skin-cleansing-methods-on-residual-chlorhexidine-skin-concentrations-and-bacterial-recovery
#17
Yoona Rhee, Louisa J Palmer, Koh Okamoto, Sean Gemunden, Khaled Hammouda, Sarah K Kemble, Michael Y Lin, Karen Lolans, Louis Fogg, Derek Guanaga, Deborah S Yokoe, Robert A Weinstein, Gyorgy Frendl, Mary K Hayden
BACKGROUND Bathing intensive care unit (ICU) patients with 2% chlorhexidine gluconate (CHG)-impregnated cloths decreases the risk of healthcare-associated bacteremia and multidrug-resistant organism transmission. Hospitals employ different methods of CHG bathing, and few studies have evaluated whether those methods yield comparable results. OBJECTIVE To determine whether 3 different CHG skin cleansing methods yield similar residual CHG concentrations and bacterial densities on skin. DESIGN Prospective, randomized 2-center study with blinded assessment...
April 2018: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/29447075/propionibacterium-acnes-has-low-susceptibility-to-chlorhexidine-digluconate
#18
Keisuke Nakase, Hanae Fukushima, Tomoko Yukawa, Hidemasa Nakaminami, Takeshi Fujii, Norihisa Noguchi
BACKGROUND: The skin bacterium Propionibacterium acnes has been reported to be responsible for surgical site infections (SSIs). Skin disinfection before surgery therefore is of the utmost importance in the prevention of SSIs caused by skin bacteria. METHODS: We assessed the susceptibility of clinical isolates of two skin bacteria, P. acnes and Staphylococcus epidermidis, to disinfectants. RESULTS: The range of chlorhexidine digluconate (CHG) minimum inhibitory concentrations (MICs) for P...
April 2018: Surgical Infections
https://www.readbyqxmd.com/read/29442090/effect-of-chemical-disinfectants-and-accelerated-aging-on-maxillofacial-silicone-elastomers-an-in-vitro-study
#19
Anna Serene Babu, V Manju, Vinod Kumar Gopal
Context: Maxillofacial prostheses need frequent refabrication due to degradation of color and deterioration of physical properties of the elastomer. Aims: This study attempted to evaluate the change in color stability, Shore A hardness, and surface roughness of two maxillofacial silicones, A-2186 and Cosmesil M511, when submitted to chemical disinfection and accelerated aging. Settings and Design: This was a comparative in vitro study. Subjects and Methods: The materials included two silicone elastomers - A-2186 and Cosmesil M511 (Factor II Incorporated) - functional intrinsic red pigment and three disinfectants - Fittydent tablet, chlorhexidine gluconate 4%, and neutral soap...
January 2018: Indian Journal of Dental Research: Official Publication of Indian Society for Dental Research
https://www.readbyqxmd.com/read/29430100/comparison-and-evaluation-of-two-reciprocating-root-canal-instruments-on-removal-of-smear-layer-by-using-two-irrigants-at-apical-one-third-of-the-root-canal-an-ex-vivo-scanning-electron-microscopic-study
#20
M M Jimna, T S Ashwini, H K Sowmya
Aim: To compare and evaluate the cleaning ability of two reciprocating systems, that is, WaveOne (WO) and self-adjusting files (SAF) in terms of removal of smear layer using sodium hypochlorite (NaOCl) and chlorhexidine gluconate (CHX) at apical one-third of the root canal. Materials and Methods: Forty-three human maxillary anterior teeth were selected. The canal was instrumented manually up to a number 25 K-file size. WO and SAF were used to prepare the root canals...
November 2017: Journal of Conservative Dentistry: JCD
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