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https://www.readbyqxmd.com/read/28223789/the-determinants-of-coping-with-pain-in-chronically-ill-geriatric-patients-the-role-of-a-sense-of-coherence
#1
Anna Andruszkiewicz, Małgorzata Anna Basińska, Mirosława Felsmann, Mariola Banaszkiewicz, Alicja Marzec, Kornelia Kędziora-Kornatowska
BACKGROUND: Given the rising population of the elderly in modern societies, the concern for their good functioning poses a challenge for the 21st century medicine and social services. Senior citizens are at an increased risk of developing chronic conditions, which in turn increase discomfort associated with physiological processes of aging. Sensations of pain have a particular influence on the mentioned discomfort, and pain is prevalent among older people. Therefore, from the perspective of an elderly person and senior care, it is crucial to identify determinants of effective coping with chronic pain...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28221820/risks-benefits-and-importance-of-collecting-sexual-orientation-and-gender-identity-data-in-healthcare-settings-a-multi-method-analysis-of-patient-and-provider-perspectives
#2
Allysha C Maragh-Bass, Maya Torain, Rachel Adler, Eric Schneider, Anju Ranjit, Lisa M Kodadek, Ryan Shields, Danielle German, Claire Snyder, Susan Peterson, Jeremiah Schuur, Brandyn Lau, Adil H Haider
PURPOSE: Research suggests that LGBT populations experience barriers to healthcare. Organizations such as the Institute of Medicine recommend routine documentation of sexual orientation (SO) and gender identity (GI) in healthcare, to reduce LGBT disparities. We explore patient views regarding the importance of SO/GI collection, and patient and provider views on risks and benefits of routine SO/GI collection in various settings. METHODS: We surveyed LGBT/non-LGBT patients and providers on their views on SO/GI collection...
February 21, 2017: LGBT Health
https://www.readbyqxmd.com/read/28220082/synaptic-and-neuronal-autoantibody-associated-psychiatric-syndromes-controversies-and-hypotheses
#3
Adam Al-Diwani, Thomas A Pollak, Alexander E Langford, Belinda R Lennox
Autoimmune encephalitis (AE) mediated by antibodies against synaptic and neuronal surface targets frequently presents with a psychiatric syndrome. In these patients, removal of autoantibodies treats the disease and outcomes are closely linked to early intervention. The discovery of these autoantibodies in isolated psychiatric syndromes has raised the possibility that these patients may derive similar benefits from immunotherapy, a potentially transformational approach to the treatment of mental illness. Although open-label case series suggest impressive therapeutic outcomes, the pathological relevance of these autoantibodies outside of canonical presentations is debated...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28217983/extraction-and-separation-of-lactate-dehydrogenase-inhibitors-from-poria-cocos-schw-wolf-based-on-a-hyphenated-technique-and-in-vitro-methods
#4
Sainan Li, Jianxu Zhang, Senlin Li, Chunming Liu, Shu Liu, Zhiqiang Liu
Stroke is one of the most common diseases worldwide. Lactate dehydrogenase inhibitors are widely used in the treatment of ischemic stroke, with natural products considered a promising source of lactate dehydrogenase inhibitors. In this study, ultrafiltration liquid chromatography coupled with mass spectrometry was used for the screening and identification of lactate dehydrogenase inhibitors from Poria cocos. Five lactate dehydrogenase inhibitors were selected: dehydropachymic acid, pachymic acid, dehydrotrametenolic acid, trametenolic acid, and eburicoic acid...
February 20, 2017: Journal of Separation Science
https://www.readbyqxmd.com/read/28211105/joint-reconstruction-of-ictal-inter-ictal-spect-data-for-improved-epileptic-foci-localization
#5
Yothin Rakvongthai, Frederic Fahey, Korn Borvorntanajanya, Supatporn Tepmongkol, Usanee Vutrapongwatana, Katherine Zukotynski, Georges El Fakhri, Jinsong Ouyang
PURPOSE: To improve the performance for localizing epileptic foci, we have developed a joint ictal/inter-ictal SPECT reconstruction method in which ictal and inter-ictal SPECT projections are simultaneously reconstructed to obtain the differential image. METHODS: We have developed a SPECT reconstruction method that jointly reconstructs ictal and inter-ictal SPECT projection data. We performed both phantom and patient studies to evaluate the performance of our joint method for epileptic foci localization as compared with the conventional subtraction method in which the differential image is obtained by subtracting the inter-ictal image from the co-registered ictal image...
February 16, 2017: Medical Physics
https://www.readbyqxmd.com/read/28205403/functionalized-calix-4-arenes-as-potential-therapeutic-agents
#6
Muhammad Moazzam Naseer, Mukhtiar Ahmed, Shahid Hameed
Calixarenes, composed of phenolic units linked by methylene bridges at the 2,6-positions, represent a versatile class of macrocyclic compounds in supramolecular chemistry that can host small molecules or ions in their well-defined hydrophobic cavities. In recent years, it has been recognized that this class of compounds has the potential to serve as platform for the design of biological active compounds. Therefore, the calixarenes functionalized with different pharmacophoric groups have been synthesized as target structure by many researchers and were further evaluated for their biological activities...
February 2017: Chemical Biology & Drug Design
https://www.readbyqxmd.com/read/28202479/improving-services-for-glaucoma-care-in-nigeria-implications-for-policy-and-programmes-to-achieve-universal-health-coverage
#7
Fatima Kyari, Clare Gilbert, Karl Blanchet, Richard Wormald
Glaucoma in Africa is sometimes referred to as the silent thief of sight. In Nigeria, glaucoma is common, it is serious, ophthalmologists face many constraints in managing it, people do not even know they have it until it is advanced, patients do not understand or comply with treatment after they are diagnosed and the poor are more likely to be glaucoma blind. Available evidence indicates that the health system in Nigeria is failing to meet the needs of patients with glaucoma. Based on evidence, we propose future directions for improving services for glaucoma care in Nigeria, and the implications for policy and programmes to control glaucoma blindness, using a health system-oriented approach...
February 15, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28198055/traditional-oriental-herbal-medicine-and-natural-killer-cells-for-cancer-patients-a-systematic-review-and-meta-analysis
#8
REVIEW
Kyeore Bae, Ji-Hye Park, Jeehye Kim, Chong-Kwan Cho, Byeongsang Oh, Daniel Costa, Stephanie Lim, Gary Deng, Hwa-Seung Yoo
Traditional oriental herbal medicine (HM) is used by cancer patients to improve immunity. Natural killer (NK) cells are associated with development and progression of tumor and survival of cancer patients. This literature review examined randomized controlled trials (RCTs) in four electronic databases until October 2015 to evaluate the effects of oral HM on NK cells in cancer patients. Data were pooled and computed in a meta-analysis. The methodological quality was assessed according to the Cochrane risk of bias tool...
February 15, 2017: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/28191681/a-time-efficient-acquisition-protocol-for-multipurpose-diffusion-weighted-microstructural-imaging-at-7-tesla
#9
Farshid Sepehrband, Kieran O'Brien, Markus Barth
PURPOSE: Several diffusion-weighted MRI techniques have been developed and validated during the past 2 decades. While offering various neuroanatomical inferences, these techniques differ in their proposed optimal acquisition design, preventing clinicians and researchers benefiting from all potential inference methods, particularly when limited time is available. This study reports an optimal design that enables for a time-efficient diffusion-weighted MRI acquisition scheme at 7 Tesla...
February 12, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28190660/overview-of-biobank-japan-follow-up-data-in-32-diseases
#10
Makoto Hirata, Akiko Nagai, Yoichiro Kamatani, Toshiharu Ninomiya, Akiko Tamakoshi, Zentaro Yamagata, Michiaki Kubo, Kaori Muto, Yutaka Kiyohara, Taisei Mushiroda, Yoshinori Murakami, Koichiro Yuji, Yoichi Furukawa, Hitoshi Zembutsu, Toshihiro Tanaka, Yozo Ohnishi, Yusuke Nakamura, Koichi Matsuda
BACKGROUND: We established a patient-oriented biobank, BioBank Japan, with information on approximately 200,000 patients, suffering from any of 47 common diseases. This follow-up survey focused on 32 diseases, potentially associated with poor vital prognosis, and collected patient survival information, including cause of death. We performed a survival analysis for all subjects to get an overview of BioBank Japan follow-up data. METHODS: A total of 141,612 participants were included...
February 9, 2017: Journal of Epidemiology
https://www.readbyqxmd.com/read/28187763/the-method-of-attachment-influences-accelerometer-based-activity-data-in-dogs
#11
Kyle W Martin, Anastasia M Olsen, Colleen G Duncan, Felix M Duerr
BACKGROUND: Accelerometer-based activity monitoring is a promising new tool in veterinary medicine used to objectively assess activity levels in dogs. To date, it is unknown how device orientation, attachment method, and attachment of a leash to the collar holding an accelerometer affect canine activity data. It was our goal to evaluate whether attachment methods of accelerometers affect activity counts. Eight healthy, client-owned dogs were fitted with two identical neck collars to which two identical activity monitors were attached using six different methods of attachment...
February 10, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28185398/reconciling-conceptualizations-of-relationships-and-person-centred-care-for-older-people-with-cognitive-impairment-in-acute-care-settings
#12
Carole Rushton, David Edvardsson
Relationships are central to enacting person-centred care of the older person with cognitive impairment. A fuller understanding of relationships and the role they play facilitating wellness and preserving personhood is critical if we are to unleash the productive potential of nursing research and person-centred care. In this article, we target the acute care setting because much of the work about relationships and older people with cognitive impairment has tended to focus on relationships in long-term care...
February 10, 2017: Nursing Philosophy: An International Journal for Healthcare Professionals
https://www.readbyqxmd.com/read/28185304/dual-echo-z-shimmed-proton-resonance-frequency-shift-magnetic-resonance-thermometry-near-metallic-ablation-probes-technique-and-temperature-precision
#13
Yuxin Zhang, Megan E Poorman, William A Grissom
PURPOSE: To improve the precision of proton resonance frequency-shift magnetic resonance thermometry near ablation probes by recovering near-probe image signals that are typically lost due to magnetic susceptibility-induced field distortions. METHODS: A dual-echo gradient-recalled echo sequence was implemented, in which the first echo was under- or over-refocused in the slice dimension to recover image signal and temperature precision near a probe, and the second echo was fully refocused to obtain image signal everywhere else in the slice...
February 10, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28183232/triterpenoids-and-polysaccharide-peptides-enriched-ganoderma-lucidum-a-randomized-double-blind-placebo-controlled-crossover-study-of-its-antioxidation-and-hepatoprotective-efficacy-in-healthy-volunteers
#14
Hui-Fang Chiu, Hui-Yu Fu, Yan-Ying Lu, Yi-Chun Han, You-Cheng Shen, Kamesh Venkatakrishnan, Oksana Golovinskaia, Chin-Kun Wang
CONTEXT: Ganoderma lucidum (Leyss: Fr) Karst. (Polyporaceae) is an oriental medicinal fungus, commonly used in traditional Chinese medicine (TCM) for treating various condition or diseases such as hypertension, hyperglycaemia, hepatitis and cancer. OBJECTIVE: The current study examines whether triterpenoids and polysaccharide-enriched G. lucidum (GL) influence antioxidation and hepatoprotective efficacy by suppressing oxidative stress. MATERIALS AND METHODS: Forty-two healthy subjects (22 male and 20 female) were recruited and segregated into two groups as experimental or placebo and requested to intake GL (n = 21) or placebo (n = 21) capsule (225 mg; after lunch or dinner) for six consecutive months and vice versa with one month washout period in between...
December 2017: Pharmaceutical Biology
https://www.readbyqxmd.com/read/28182485/-wolves-canis-lupus-and-dogs-canis-familiaris-differ-in-following-human-gaze-into-distant-space-but-respond-similar-to-their-packmates-gaze-correction-to-werhahn-et-al-2016
#15
(no author information available yet)
Reports an error in "Wolves (Canis lupus) and dogs (Canis familiaris) differ in following human gaze into distant space but respond similar to their packmates' gaze" by Geraldine Werhahn, Zsófia Virányi, Gabriela Barrera, Andrea Sommese and Friederike Range (Journal of Comparative Psychology, 2016[Aug], Vol 130[3], 288-298). In the article, the affiliations for the second and fifth authors should be Wolf Science Center, Ernstbrunn, Austria, and Comparative Cognition, Messerli Research Institute, University of Veterinary Medicine Vienna/ Medical University of Vienna/University of Vienna...
February 2017: Journal of Comparative Psychology
https://www.readbyqxmd.com/read/28178910/medtalks-developing-teaching-abilities-and-experience-in-undergraduate-medical-students
#16
Suhair Bandeali, Albert Chiang, Christopher J Ramnanan
OBJECTIVES: According to the CanMEDS' Scholar competency, physicians are expected to facilitate the learning of colleagues, patients and other health professionals. However, most medical students are not provided with formal opportunities to gain teaching experience with objective feedback. METHODS: To address this, the University's Medical Education Interest Group (MEIG) created a pilot teaching program in January 2015 entitled 'MedTalks'. Four 3-hour sessions were held at the University Faculty of Medicine, where first and second year medical students taught clinically oriented topics to undergraduate university students...
2017: Medical Education Online
https://www.readbyqxmd.com/read/28173635/an-assessment-of-the-experiences-and-needs-of-adolescents-with-chronic-conditions-in-transitional-care-a-qualitative-study-to-develop-a-patient-education-programme
#17
Franziska Bomba, Carsten Herrmann-Garitz, Julia Schmidt, Silke Schmidt, Ute Thyen
The transition of adolescents with chronic conditions is a challenging task. This study aimed to explore the experiences and needs of adolescents with chronic conditions in the transition period and to apply these findings to the design of a generic patient education programme. Data were collected from a sample of 29 adolescents with chronic conditions from Northern Germany and Switzerland including a broad range of views due to variation in disease management and organisation of care both in paediatric and adult populations...
March 2017: Health & Social Care in the Community
https://www.readbyqxmd.com/read/28170280/super-users-at-an-acupuncture-and-oriental-medicine-teaching-clinic-demographics-and-unique-clinical-characteristics
#18
Forrest Cooper, Benjamin L Marx, Tamsin L Lee, Deborah Espesete
OBJECTIVE: The use of acupuncture in the United States has consistently grown over the last two decades, and the National Center for Complementary and Integrative Health has recently called for greater understanding of "real life outcomes and use" by complementary and alternative medicine users. This study assesses the demographics and utilization patterns of "super-users" treated at the Oregon College of Oriental Medicine intern clinic. METHODS: This was a retrospective chart review at the Oregon College of Oriental Medicine (OCOM) intern clinic, a large acupuncture and oriental medicine (AOM) school in Portland, Oregon...
February 7, 2017: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/28166896/usability-evaluation-of-an-emergency-department-information-system-prototype-designed-using-cognitive-systems-engineering-techniques
#19
Lindsey N Clark, Natalie C Benda, Sudeep Hegde, Nicolette M McGeorge, Theresa K Guarrera-Schick, A Zachary Hettinger, David T LaVergne, Shawna J Perry, Robert L Wears, Rollin J Fairbanks, Ann M Bisantz
This article presents an evaluation of novel display concepts for an emergency department information system (EDIS) designed using cognitive systems engineering methods. EDISs assist emergency medicine staff with tracking patient care and ED resource allocation. Participants performed patient planning and orientation tasks using the EDIS displays and rated the display's ability to support various cognitive performance objectives along with the usability, usefulness, and predicted frequency of use for 18 system components...
April 2017: Applied Ergonomics
https://www.readbyqxmd.com/read/28164429/rethinking-empathy-decline-results-from-an-osce
#20
Valerie Chan Teng, Cathina Nguyen, Karen Thomson Hall, Tracy Rydel, Amelia Sattler, Erika Schillinger, Eva Weinlander, Steven Lin
BACKGROUND: The phenomenon of empathy decline among medical students during training is widely accepted, with evidence based largely on studies using self-administered instruments. Recently, researchers have called into question this phenomenon, in light of new findings that suggest a discrepancy between self-administered empathy scores and observed empathic behaviours: for example, during objective structured clinical examinations (OSCEs). Our objective was to compare observed empathy among medical students in different clerkship years using an OSCE...
February 6, 2017: Clinical Teacher
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