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https://www.readbyqxmd.com/read/29028361/new-findings-on-biological-actions-and-clinical-applications-of-royal-jelly-a-review
#1
Mozafar Khazaei, Atefe Ansarian, Elham Ghanbari
Royal jelly (RJ) is a natural bee product with great potential for use in medicine. The chemical composition of RJ indicates the presence of various bioactive substances including 10-hydroxydecanoic acid and 24-methylenecholesterol. In addition, a number of biological and pharmacological activities of RJ have been documented. The aim of this study was to review the biological and medical effects of RJ. The search was conducted in articles from electronic and scientific literature databases such as Pub Med, Science Direct, Scopus, Medline, and ISI Web of Science published from 1990 to 2017 using keywords of pharmacological, biological, and clinical effects and royal jelly...
October 13, 2017: Journal of Dietary Supplements
https://www.readbyqxmd.com/read/29027025/spontaneous-integration-of-temporal-information-implications-for-representational-computational-capacity-of-animals
#2
REVIEW
Ezgi Gür, Yalçın Akın Duyan, Fuat Balcı
How do animals adapt their behaviors to changing conditions? This question relates to the debate between associative versus representational/computational approaches in cognitive science. An influential line of research that has significantly shaped the conceptual development of animal learning over decades has primarily focused on the role of associative dynamics with little-to-no ascription of representational/combinatorial capacities. The common assumption of these models is that behavioral adjustments are incremental and they result from updating of associations based on actions and their outcomes, without encoding the critical information serving as the determinant(s) of such contingencies (e...
October 12, 2017: Animal Cognition
https://www.readbyqxmd.com/read/29025004/dietary-patterns-and-risk-of-pancreatic-cancer-a-systematic-review
#3
Jiali Zheng, Mark A Guinter, Anwar T Merchant, Michael D Wirth, Jiajia Zhang, Rachael Z Stolzenberg-Solomon, Susan E Steck
Pancreatic cancer has the highest case fatality rate of all major cancers. : A systematic review using PRISMA guidelines was conducted to summarize the associations between dietary patterns and risk of pancreatic cancer. : PubMed and Web of Science databases were searched for case-control and cohort studies published up to June 15, 2016. : Eligible studies included a dietary pattern as exposure and pancreatic cancer incidence or mortality as outcome and reported odds ratios, hazard ratios, or relative risks, along with corresponding 95%CIs...
September 6, 2017: Nutrition Reviews
https://www.readbyqxmd.com/read/29024520/allergen-immunotherapy-exploring-areas-for-further-inquiry
#4
Tam Ramsey, Wanda Lai, Peter F Svider, Houmehr Hojjat, Jean Anderson Eloy, Adam J Folbe
BACKGROUND: Allergy-related illness impacts millions of individuals worldwide. Our objectives were to characterize current trends of clinical trials research relating to allergen immunotherapy and to describe the landscape of allergen immunotherapy in National Institutes of Health (NIH)-supported research inquiry. METHODS: On ClinicalTrials.gov, the following terms were searched: allergen immunotherapy OR allergy immunotherapy. Variables, including completion status, dates, design, study population, funder, location, and allergen were recorded...
October 12, 2017: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/29022513/discrepancies-in-animal-models-of-preterm-birth
#5
Clarence R Manuel, Charles R Ashby, Sandra E Reznik
BACKGROUND: Preterm birth (PTB) is a multifactorial syndrome occurring before the 37th week of full-term pregnancy [1]. Babies delivered preterm experience short-term and long-term complications affecting multiple organ systems, and serious maternal complications include hemorrhage and infection. Each year, an estimated 15 million babies are born preterm, and complications from prematurity are the leading cause of death among children up to 5 years of age [2]. With another increase in PTB rates over the last several years, the United States continues to have the highest incidence of any industrialized country [3]...
October 12, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/29022344/development-of-photoacoustic-probes-for-in-vivo-molecular-imaging
#6
Christopher J Reinhardt, Jefferson Chan
Photoacoustic (PA) imaging is an emerging, non-invasive imaging modality that encompasses attributes of both optical and ultrasound imaging. Because of the combination of optical excitation and acoustic detection, PA imaging enables high contrast and high resolution within deep tissue (centimeter depths). Recent advances in PA probe development have allowed for stimulus-responsive imaging in a variety of biological models with implications for basic, translational, and clinical sciences. This perspective highlights recent progress in the development of PA probes and their application to live-animal molecular imaging...
October 12, 2017: Biochemistry
https://www.readbyqxmd.com/read/29018832/pharyngeal-myiasis-caused-by-sheep-botfly-oestrus-ovis-diptera-oestridae-larva-tabriz-east-azarbaijan-province-iran-a-case-report
#7
Teimour Hazratian, Ali Tagizadeh, Mohammad Chaichi, Madineh Abbasi
Myiasis is caused by the larvae of flies infesting animal or human tissues and organs. This report aims to present a case of pharyngeal myiasis caused by the larvae of Oestrus ovis (Diptera: Oestridae). A 55-yr old drug addict living in the Shahindeje village of Western Azerbaijan Province, northwestern Iran was referred to the Emam Reza Hospital in Tabriz, having a medical history of Chronic Obstructive Pulmonary Disease (COPD) and hospitalized due to respiratory distress, 20 days ago. He was intubated with a mechanical ventilator (MV) because of his respiratory distress condition...
March 2017: Journal of Arthropod-borne Diseases
https://www.readbyqxmd.com/read/29017666/protective-effects-of-nigella-sativaon-acetylsalicylic-acid-induced-nephrotoxicity-in-albino-rats
#8
Sania Asif, Lubna Malik
OBJECTIVE: To see the effects of Nigella sativaon acetylsalicylic acid-induced nephrotoxicity in albino rats. STUDY DESIGN: An experimental study. PLACE AND DURATION OF STUDY: The Anatomy Department of University of Health Sciences, Lahore, from January 2014 to December 2015. METHODOLOGY: Thirty-two female albino rats were divided into four groups. Group A(control) was given single dose of 10 mg/100 gm body weight of 1% methylcellulose, orally...
September 2017: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/29016679/perimenopause-and-emergence-of-an-alzheimer-s-bioenergetic-phenotype-in-brain-and-periphery
#9
Lisa Mosconi, Valentina Berti, Crystal Guyara-Quinn, Pauline McHugh, Gabriella Petrongolo, Ricardo S Osorio, Christopher Connaughty, Alberto Pupi, Shankar Vallabhajosula, Richard S Isaacson, Mony J de Leon, Russell H Swerdlow, Roberta Diaz Brinton
After advanced age, female sex is the major risk factor for Alzheimer's disease (AD). The biological mechanisms underlying the increased AD risk in women remain largely undetermined. Preclinical studies identified the perimenopause to menopause transition, a neuroendocrine transition state unique to the female, as a sex-specific risk factor for AD. In animals, estrogenic regulation of cerebral glucose metabolism (CMRglc) falters during perimenopause. This is evident in glucose hypometabolism and decline in mitochondrial efficiency which is sustained thereafter...
2017: PloS One
https://www.readbyqxmd.com/read/28991359/association-between-the-gut-microbiota-and-mineral-metabolism
#10
REVIEW
Katarzyna Skrypnik, Joanna Suliburska
The aim of this review is to present the most recent scientific evidence of interactions between the intestinal microbiota and minerals, and the effect of this interaction on the health of the host. The Web of Science database from the years 2013-2017 on this topic was reviewed. Numerous in vitro studies have shown that iron significantly affects the intestinal microbiota. However, Bifidobacteriaceae are capable of binding iron in the large intestine, thereby limiting the formation of free radicals synthesized in the presence of iron, and thus reducing the risk of colorectal cancer...
October 9, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28989253/psidium-guajava-a-single-plant-for-multiple-health-problems-of-rural-indian-population
#11
REVIEW
Poonam G Daswani, Manasi S Gholkar, Tannaz J Birdi
The rural population in India faces a number of health problems and often has to rely on local remedies. Psidium guajava Linn. (guava), a tropical plant which is used as food and medicine can be used by rural communities due to its several medicinal properties. A literature search was undertaken to gauge the rural health scenario in India and compile the available literature on guava so as to reflect its usage in the treatment of multiple health conditions prevalent in rural communities. Towards this, electronic databases such as Pubmed, Science Direct, google scholar were scanned...
July 2017: Pharmacognosy Reviews
https://www.readbyqxmd.com/read/28985113/droplets-as-liquid-robots
#12
Jitka Čejková, Taisuke Banno, Martin M Hanczyc, František Štěpánek
Liquid droplets are very simple objects present in our everyday life. They are extremely important for many natural phenomena as well as for a broad variety of industrial processes. The conventional research areas in which the droplets are studied include physical chemistry, fluid mechanics, chemical engineering, materials science, and micro- and nanotechnology. Typical studies include phenomena such as condensation and droplet formation, evaporation of droplets, or wetting of surfaces. The present article reviews the recent literature that employs droplets as animated soft matter...
October 6, 2017: Artificial Life
https://www.readbyqxmd.com/read/28983923/the-highs-and-lows-of-programmed-cardiovascular-disease-by-developmental-hypoxia-studies-in-the-chicken-embryo
#13
N Itani, C E Salinas, M Villena, K L Skeffington, C Beck, E Villamor, C E Blanco, D A Giussani
It is now established that adverse conditions during pregnancy can trigger a fetal origin of cardiovascular dysfunction and/or increase the risk of heart disease in later life. Sub-optimal environmental conditions during early life that may promote the development of cardiovascular dysfunction in the offspring include alterations in fetal oxygenation and nutrition as well as fetal exposure to stress hormones, such as glucocorticoids. There has been growing interest in identifying the partial contributions of each of these stressors to programming of cardiovascular dysfunction...
October 5, 2017: Journal of Physiology
https://www.readbyqxmd.com/read/28979172/reversing-factor-xa-inhibitors-clinical-utility-of-andexanet-alfa
#14
REVIEW
Scott Kaatz, Hardik Bhansali, Joseph Gibbs, Robert Lavender, Charles E Mahan, David G Paje
Approximately half of patients started on an oral anticoagulant in the USA now receive one of the newer direct oral anticoagulants (DOACs). Although there is an approved reversal agent for the direct thrombin inhibitor dabigatran, a specific reversal agent for the anti-factor Xa (FXa) DOACs has yet to be licensed. Unlike the strategy to reverse the only oral direct thrombin inhibitor with idarucizumab, which is a humanized monoclonal antibody fragment, a different approach is necessary to design a single agent that can reverse multiple anti-FXa medications...
2017: Journal of Blood Medicine
https://www.readbyqxmd.com/read/28974681/motionless-volumetric-photoacoustic-microscopy-with-spatially-invariant-resolution
#15
Jiamiao Yang, Lei Gong, Xiao Xu, Pengfei Hai, Yuecheng Shen, Yuta Suzuki, Lihong V Wang
Photoacoustic microscopy (PAM) is uniquely positioned for biomedical applications because of its ability to visualize optical absorption contrast in vivo in three dimensions. Here we propose motionless volumetric spatially invariant resolution photoacoustic microscopy (SIR-PAM). To realize motionless volumetric imaging, SIR-PAM combines two-dimensional Fourier-spectrum optical excitation with single-element depth-resolved photoacoustic detection. To achieve spatially invariant lateral resolution, propagation-invariant sinusoidal fringes are generated by a digital micromirror device...
October 3, 2017: Nature Communications
https://www.readbyqxmd.com/read/28968196/report-of-workshop-on-euthanasia-for-zebrafish-a-matter-of-welfare-and-science
#16
Almut Köhler, Chereen Collymore, Karin Finger-Baier, Robert Geisler, Larissa Kaufmann, Kieran C Pounder, Stefan Schulte-Merker, Ana Valentim, Zoltan M Varga, Jürgen Weiss, Uwe Strähle
The increasing importance of zebrafish as a biomedical model organism is reflected by the steadily growing number of publications and laboratories working with this species. Regulatory recommendations for euthanasia as issued in Directive 2010/63/EU are, however, based on experience with fish species used for food production and do not take the small size and specific physiology of zebrafish into account. Consequently, the currently recommended methods of euthanasia in the Directive 2010/63/EU are either not applicable or may interfere with research goals...
October 2, 2017: Zebrafish
https://www.readbyqxmd.com/read/28961457/evolutionary-processes-in-suicide
#17
REVIEW
Bruno Chiurliza, Megan L Rogers, Matthew E Schneider, Carol Chu, Thomas E Joiner
Suicidal behavior contains several dynamic elements. Due to its complexity, empirical science may approach suicide through various avenues. One underutilized approach is taking an evolutionary perspective. Our review of the literature presents two evolutionary processes that may be implicated in suicidal behavior, namely eusocial behavior and antipredator response behaviors. Studies have indicated that aspects of suicidal behavior parallel self-sacrificial behavior in eusocial animals, and that systems similar to hyperarousal-shutdown systems involved in antipredator behaviors may be activated among suicidal individuals...
September 14, 2017: Current Opinion in Psychology
https://www.readbyqxmd.com/read/28960677/mesenchymal-stem-cells-the-moniker-fits-the-science
#18
Siddaraju V Boregowda, Cori N Booker, Donald G Phinney
Mesenchymal stem cells (MSCs) have gained widespread use in regenerative medicine due to their demonstrated efficacy in a broad range of experimental animal models of disease and their excellent safety profile in human clinical trials. Outcomes from these studies suggest that MSCs achieve therapeutic effects in vivo in non-homologous applications predominantly by paracrine action. This paracrine-centric viewpoint has become widely entrenched in the field, and has spurred a campaign to rename MSCs as "medicinal signaling cells" to better reflect this mode of action...
September 28, 2017: Stem Cells
https://www.readbyqxmd.com/read/28960127/use-of-short-animal-themed-videos-to-enhance-veterinary-students-mood-attention-and-understanding-of-pharmacology-lectures
#19
Lori R Kogan, Pete Hellyer, Tod R Clapp, Erica Suchman, Jennifer McLean, Regina Schoenfeld-Tacher
Professional DVM training is inherently stressful and challenging for students. This study evaluated a simple intervention-short breaks during a veterinary pharmacology lecture course in the form of funny/cute animal videos (Mood Induction Procedures, or MIP)-to assess for potential impact on students' mood, interest in material, and perceived understanding of material. Ten YouTube video clips showing cats or dogs were selected to influence students' affective states. The videos were shown in a required pharmacology class offered during the fall semester of the second year of the DVM program at a large, land-grant institution in the Western US...
September 29, 2017: Journal of Veterinary Medical Education
https://www.readbyqxmd.com/read/28955187/comparative-medicine-an-inclusive-crossover-discipline%C3%A2-%C3%A2-%C3%A2
#20
REVIEW
James Macy, Tamas L Horvath
Comparative Medicine is typically defined as a discipline which relates and leverages the biological similarities and differences among animal species to better understand the mechanism of human and animal disease. It has also been defined as a field of study concentrating on similarities and differences between human and veterinary medicine and is increasingly associated with animal models of human disease, including the critical role veterinarians, animal resource centers, and Institutional Animal Care and Use Committees play in facilitating and ensuring humane and reproducible laboratory animal care and use...
September 2017: Yale Journal of Biology and Medicine
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