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James Maxwell

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https://www.readbyqxmd.com/read/29217151/ontologies-of-life-from-thermodynamics-to-teleonomics-comment-on-answering-schr%C3%A3-dinger-s-question-a-free-energy-formulation-by-maxwell-james-d%C3%A3-sormeau-ramstead-et-al
#1
https://www.readbyqxmd.com/read/29204296/quality-of-life-of-people-living-with-hiv-aids-in-the-ho-municipality-ghana-a-cross-sectional-study
#2
James Osei-Yeboah, William K B A Owiredu, Gameli Kwame Norgbe, Sylvester Yao Lokpo, Christian Obirikorang, Emmanuel Alote Allotey, John Gameli Deku, Emmanuel Akomanin Asiamah, Nana Yaw Barimah Manaphraim, Prince Senyo Kwasi Nyamadi, Edward Yiadom Boakye, Tibemponi Ntoni, Roseline Avorkliyah, Romeo Asumbasiya Aduko, Seyram Tetteh Quarshie, Maxwell Jenkins Gbemu
Quality of life (QoL) is an important component in the evaluation of the wellbeing of people living with HIV/AIDS (PLHIV). This study was aimed at evaluating the QoL of PLHIV attending the antiretroviral clinics in the Ho municipality. A cross-sectional study was conducted from January 2017 to April 2017 involving 158 purposively selected HIV-positive patients who were attending the antiretroviral clinics both in the Volta Regional Hospital and Ho Municipal Hospital. An Interviewer administered standard questionnaire (WHOQOL-HIV Bref) was used to collect information on sociodemography, medical history, and the quality of life (QoL) of the respondents...
2017: AIDS Research and Treatment
https://www.readbyqxmd.com/read/29195651/no-actual-measurement-%C3%A2-was-required-maxwell-and-cavendish-s-null-method-for-the-inverse-square-law-of-electrostatics
#3
Isobel Falconer
In 1877 James Clerk Maxwell and his student Donald MacAlister refined Henry Cavendish's 1773 null experiment demonstrating the absence of electricity inside a charged conductor. This null result was a mathematical prediction of the inverse square law of electrostatics, and both Cavendish and Maxwell took the experiment as verifying the law. However, Maxwell had already expressed absolute conviction in the law, based on results of Michael Faraday's. So, what was the value to him of repeating Cavendish's experiment? After assessing whether the law was as secure as he claimed, this paper explores its central importance to the electrical programme that Maxwell was pursuing...
October 2017: Studies in History and Philosophy of Science
https://www.readbyqxmd.com/read/29191410/embodying-markov-blankets-comment-on-answering-schr%C3%A3-dinger-s-question-a-free-energy-formulation-by-maxwell-james-d%C3%A3-sormeau-ramstead-et-al
#4
Giovanni Pezzulo, Michael Levin
No abstract text is available yet for this article.
November 24, 2017: Physics of Life Reviews
https://www.readbyqxmd.com/read/29174781/utilization-of-veno-arterial-extracorporeal-membrane-oxygenation-for-massive-pulmonary-embolism
#5
Chetan Pasrija, Anthony Kronfli, Praveen George, Maxwell Raithel, Francesca Boulos, Daniel L Herr, James S Gammie, Si M Pham, Bartley P Griffith, Zachary N Kon
BACKGROUND: The management of massive pulmonary embolism remains challenging, with a considerable mortality rate. Although veno-arterial extracorporeal membrane oxygenation (VA-ECMO) for massive pulmonary embolism has been reported, its use as salvage therapy has been associated with poor outcomes. We reviewed our experience utilizing an aggressive, protocolized approach of VA-ECMO to triage, optimize, and treat these patients. METHODS: All patients with a massive pulmonary embolism who were placed on VA-ECMO, as an initial intervention determined by protocol, were retrospectively reviewed...
November 23, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29174555/predictive-modeling-for-determination-of-microscopic-residual-disease-at-primary-cytoreduction-an-nrg-oncology-gynecologic-oncology-group-182-study
#6
Neil S Horowitz, G Larry Maxwell, Austin Miller, Chad A Hamilton, Bunja Rungruang, Noah Rodriguez, Scott D Richard, Thomas C Krivak, Jeffrey M Fowler, David G Mutch, Linda Van Le, Roger B Lee, Peter Argenta, David Bender, Krishnansu S Tewari, David Gershenson, James J Java, Michael A Bookman
OBJECTIVE: Microscopic residual disease following complete cytoreduction (R0) is associated with a significant survival benefit for patients with advanced epithelial ovarian cancer (EOC). Our objective was to develop a prediction model for R0 to support surgeons in their clinical care decisions. METHODS: Demographic, pathologic, surgical, and CA125 data were collected from GOG 182 records. Patients enrolled prior to September 1, 2003 were used for the training model while those enrolled after constituted the validation data set...
November 22, 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/29158029/beyond-blanket-terms-challenges-for-the-explanatory-value-of-variational-neuro-ethology-comment-on-answering-schr%C3%A3-dinger-s-question-a-free-energy-formulation-by-maxwell-james-d%C3%A3-sormeau-ramstead-et-al
#7
https://www.readbyqxmd.com/read/29129485/living-systems-do-not-minimize-free-energy-comment-on-answering-schr%C3%A3-dinger-s-question-a-free-energy-formulation-by-maxwell-james-d%C3%A3-sormeau-ramstead-et-al
#8
Leonid M Martyushev
No abstract text is available yet for this article.
November 9, 2017: Physics of Life Reviews
https://www.readbyqxmd.com/read/29122565/cultural-markov-blankets-mind-the-other-minds-gap-comment-on-answering-schr%C3%A3-dinger-s-question-a-free-energy-formulation-by-maxwell-james-d%C3%A3-sormeau-ramstead-et-al
#9
https://www.readbyqxmd.com/read/29122563/towards-a-unification-of-evolutionary-dynamics-comment-on-answering-schr%C3%A3-dinger-s-question-a-free-energy-formulation-by-maxwell-james-d%C3%A3-sormeau-ramstead-et-al
#10
https://www.readbyqxmd.com/read/29122562/lifting-the-markov-blankets-of-socio-cultural-evolution-a-comment-on-answering-schr%C3%A3-dinger-s-question-a-free-energy-formulation-by-maxwell-james-d%C3%A3-sormeau-ramstead-et-al
#11
https://www.readbyqxmd.com/read/29119134/erratum-author-correction-the-contribution-of-pathogenic-variants-in-breast-cancer-susceptibility-genes-to-familial-breast-cancer-risk
#12
Thomas P Slavin, Kara N Maxwell, Jenna Lilyquist, Joseph Vijai, Susan L Neuhausen, Steve N Hart, Vignesh Ravichandran, Tinu Thomas, Ann Maria, Danylo Villano, Kasmintan A Schrader, Raymond Moore, Chunling Hu, Bradley Wubbenhorst, Brandon M Wenz, Kurt D'Andrea, Mark E Robson, Paolo Peterlongo, Bernardo Bonanni, James M Ford, Judy E Garber, Susan M Domchek, Csilla Szabo, Kenneth Offit, Katherine L Nathanson, Jeffrey N Weitzel, Fergus J Couch
[This corrects the article DOI: 10.1038/s41523-017-0024-8.].
2017: NPJ Breast Cancer
https://www.readbyqxmd.com/read/29096948/the-lancet-countdown-on-health-and-climate-change-from-25-years-of-inaction-to-a-global-transformation-for-public-health
#13
REVIEW
Nick Watts, Markus Amann, Sonja Ayeb-Karlsson, Kristine Belesova, Timothy Bouley, Maxwell Boykoff, Peter Byass, Wenjia Cai, Diarmid Campbell-Lendrum, Jonathan Chambers, Peter M Cox, Meaghan Daly, Niheer Dasandi, Michael Davies, Michael Depledge, Anneliese Depoux, Paula Dominguez-Salas, Paul Drummond, Paul Ekins, Antoine Flahault, Howard Frumkin, Lucien Georgeson, Mostafa Ghanei, Delia Grace, Hilary Graham, Rébecca Grojsman, Andy Haines, Ian Hamilton, Stella Hartinger, Anne Johnson, Ilan Kelman, Gregor Kiesewetter, Dominic Kniveton, Lu Liang, Melissa Lott, Robert Lowe, Georgina Mace, Maquins Odhiambo Sewe, Mark Maslin, Slava Mikhaylov, James Milner, Ali Mohammad Latifi, Maziar Moradi-Lakeh, Karyn Morrissey, Kris Murray, Tara Neville, Maria Nilsson, Tadj Oreszczyn, Fereidoon Owfi, David Pencheon, Steve Pye, Mahnaz Rabbaniha, Elizabeth Robinson, Joacim Rocklöv, Stefanie Schütte, Joy Shumake-Guillemot, Rebecca Steinbach, Meisam Tabatabaei, Nicola Wheeler, Paul Wilkinson, Peng Gong, Hugh Montgomery, Anthony Costello
No abstract text is available yet for this article.
October 30, 2017: Lancet
https://www.readbyqxmd.com/read/29079472/6-substituted-quinolines-as-ror%C3%AE-t-inverse-agonists
#14
J Kent Barbay, Maxwell D Cummings, Marta Abad, Glenda Castro, Kevin D Kreutter, David A Kummer, Umar Maharoof, Cynthia Milligan, Rachel Nishimura, Joan Pierce, Celine Schalk-Hihi, John Spurlino, Virginia M Tanis, Maud Urbanski, Hariharan Venkatesan, Aihua Wang, Craig Woods, Ronald Wolin, Xiaohua Xue, James P Edwards, Anne M Fourie, Kristi Leonard
We identified 6-substituted quinolines as modulators of the retinoic acid receptor-related orphan receptor gamma t (RORγt). The synthesis of this class of RORγt modulators is reported, and optimization of the substituents at the quinoline 6-position that produced compounds with high affinity for the receptor is detailed. This effort identified molecules that act as potent, full inverse agonists in a RORγt-driven cell-based reporter assay. The X-ray crystal structures of two full inverse agonists from this chemical series bound to the RORγt ligand binding domain are disclosed, and we highlight the interaction of a hydrogen-bond acceptor on the 6-position substituent of the inverse agonist with Glu379:NH as a conserved binding contact...
October 16, 2017: Bioorganic & Medicinal Chemistry Letters
https://www.readbyqxmd.com/read/29075258/quantitative-characterization-of-the-t-cell-receptor-repertoire-of-na%C3%A3-ve-and-memory-subsets-using-an-integrated-experimental-and-computational-pipeline-which-is-robust-economical-and-versatile
#15
Theres Oakes, James M Heather, Katharine Best, Rachel Byng-Maddick, Connor Husovsky, Mazlina Ismail, Kroopa Joshi, Gavin Maxwell, Mahdad Noursadeghi, Natalie Riddell, Tabea Ruehl, Carolin T Turner, Imran Uddin, Benny Chain
The T cell receptor (TCR) repertoire can provide a personalized biomarker for infectious and non-infectious diseases. We describe a protocol for amplifying, sequencing, and analyzing TCRs which is robust, sensitive, and versatile. The key experimental step is ligation of a single-stranded oligonucleotide to the 3' end of the TCR cDNA. This allows amplification of all possible rearrangements using a single set of primers per locus. It also introduces a unique molecular identifier to label each starting cDNA molecule...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/29072885/cardiopulmonary-ultrasound-for-critically-ill-adults-improves-diagnostic-accuracy-in-a-resource-limited-setting-the-africa-trial
#16
Torben K Becker, Chelsea A Tafoya, Maxwell Osei-Ampofo, Matthew J Tafoya, Ross A Kessler, Nikhil Theyyunni, Hussein A Yakubu, Daniel Opuni, Daniel J Clauw, James A Cranford, Chris K Oppong, Rockefeller A Oteng
OBJECTIVE: To assess the effects of a cardiopulmonary ultrasound (CPUS) examination on diagnostic accuracy for critically ill patients in a resource-limited setting. METHODS: Approximately half of the emergency medicine resident physicians at the Komfo Anokye Teaching Hospital (KATH) in Kumasi, Ghana, were trained in a CPUS protocol. Adult patients triaged to the resuscitation area of the emergency department (ED) were enrolled if they exhibited signs or symptoms of shock or respiratory distress...
October 26, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/29066075/dynamics-and-equilibria-of-living-systems-comment-on-answering-schr%C3%A3-dinger-s-question-a-free-energy-formulation-by-maxwell-james-d%C3%A3-sormeau-ramstead-et-al
#17
Nicola Bellomo, Ahmed Elaiw
No abstract text is available yet for this article.
October 19, 2017: Physics of Life Reviews
https://www.readbyqxmd.com/read/29050920/critique-of-pure-free-energy-principle-comment-on-answering-schr%C3%A3-dinger-s-question-a-free-energy-formulation-by-maxwell-james-d%C3%A3-sormeau-ramstead-et-al
#18
Arturo Tozzi, James F Peters
No abstract text is available yet for this article.
October 16, 2017: Physics of Life Reviews
https://www.readbyqxmd.com/read/29029962/answering-schr%C3%A3-dinger-s-question-a-free-energy-formulation
#19
REVIEW
Maxwell James Désormeau Ramstead, Paul Benjamin Badcock, Karl John Friston
The free-energy principle (FEP) is a formal model of neuronal processes that is widely recognised in neuroscience as a unifying theory of the brain and biobehaviour. More recently, however, it has been extended beyond the brain to explain the dynamics of living systems, and their unique capacity to avoid decay. The aim of this review is to synthesise these advances with a meta-theoretical ontology of biological systems called variational neuroethology, which integrates the FEP with Tinbergen's four research questions to explain biological systems across spatial and temporal scales...
September 20, 2017: Physics of Life Reviews
https://www.readbyqxmd.com/read/28989775/celebrating-30-years-of-science-from-the-james-clerk-maxwell-telescope
#20
REVIEW
Ian Robson, Wayne S Holland, Per Friberg
The James Clerk Maxwell Telescope (JCMT) has been the world's most successful single-dish telescope at submillimetre wavelengths since it began operations in 1987. From the pioneering days of single-element photometers and mixers, through to the state-of-the-art imaging and spectroscopic cameras, the JCMT has been associated with a number of major scientific discoveries. Famous for the discovery of 'SCUBA' galaxies, which are responsible for a large fraction of the far-infrared background, the JCMT has pushed the sensitivity limits arguably more than any other facility in this most difficult of wavebands in which to observe...
September 2017: Royal Society Open Science
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