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https://www.readbyqxmd.com/read/29785422/super-resolution-force-spectroscopy-reveals-ribosomal-motion-at-sub-nucleotide-steps
#1
Haina Jia, Yuhong Wang, Shoujun Xu
Probing biomolecular motion beyond a single nucleotide is technically challenging but fundamentally significant. We have developed super-resolution force spectroscopy (SURFS) with 0.5 pN force resolution and revealed that the ribosome moves by half a nucleotide upon the formation of the pre-translocation complex, which is beyond the resolution of other techniques.
May 22, 2018: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/29781908/musculoskeletal-injury-in-paddle-sport-athletes
#2
Andrew R Griffin, Diana M Perriman, Teresa M Neeman, Paul N Smith
INTRODUCTION: Kayak racing has been an Olympic sport since 1936. The sport is evolving with the introduction of ocean skis and stand-up-paddle boards (SUP). Musculoskeletal injury incidence surveys have been conducted for ultra-marathon events, but no data have been published for other racing formats. OBJECTIVE: To identify and compare the rates and types of injuries sustained by paddling athletes as a function of discipline and training parameters in Sprint, Marathon, Ultra-Marathon, and Ocean events...
May 16, 2018: Clinical Journal of Sport Medicine: Official Journal of the Canadian Academy of Sport Medicine
https://www.readbyqxmd.com/read/29770591/surf-an-innovative-framework-in-biosecurity-and-animal-health-surveillance-evaluation
#3
Petra Muellner, Jonathan Watts, Paul Bingham, Mark Bullians, Brendan Gould, Anjali Pande, Tim Riding, Paul Stevens, Daan Vink, Katharina Dc Stärk
Surveillance for biosecurity hazards is being conducted by the New Zealand Competent Authority, the Ministry for Primary Industries (MPI) to support New Zealand's biosecurity system. Surveillance evaluation should be an integral part of the surveillance life cycle, as it provides a means to identify and correct problems and to sustain and enhance the existing strengths of a surveillance system. The surveillance evaluation Framework (SurF) presented here was developed to provide a generic framework within which the MPI biosecurity surveillance portfolio, and all of its components, can be consistently assessed...
May 16, 2018: Transboundary and Emerging Diseases
https://www.readbyqxmd.com/read/29760868/non-medical-use-of-prescription-drugs-by-young-men-impact-of-potentially-traumatic-events-and-of-social-environmental-stressors
#4
Ansgar Rougemont-Bücking, Véronique S Grazioli, Simon Marmet, Jean-Bernard Daeppen, Mélissa Lemoine, Gerhard Gmel, Joseph Studer
Background : Non-medical use of prescription drugs (NMUPD) is an increasing phenomenon associated with physical and psychological consequences. This study investigated the effects of distinct forms of stress on NMUPD. Methods : Data from 5308 young adult men from the Swiss cohort study on substance use risk factors (C-SURF) were analysed regarding NMUPD of sleeping pills, tranquilizers, opioid analgesics, psychostimulants, and antidepressants. Various forms of stress (discrete, potentially traumatic events, recent and long-lasting social-environmental stressors) during the period preceding the NMUPD assessment were measured...
2018: European Journal of Psychotraumatology
https://www.readbyqxmd.com/read/29750341/aqua-vitae-aqua-permanens-dreaming-drowning-swimming-and-surfing-in-analysis
#5
Marilyn Mathew
In response to the question 'Who is My Jung?', this paper describes the profound personal impact of Jung's creative / artistic approach to the unconscious, beginning with my discovery of The Red Book at the age of twelve. Echoing the flow of my own dream-life, I trace the course of two analyses through the alchemical process of solutio, which began with numinous dreams of tidal waves and plunged us into inter- and intra-psychic analytic relationships that evoked vestigial memories of our first aquatic world in utero...
June 2018: Journal of Analytical Psychology
https://www.readbyqxmd.com/read/29744017/spontaneous-recanalization-after-carotid-artery-dissection-the-case-for-an-ultrasound-only-monitoring-strategy
#6
Sarah Lumsden, Gabor Rosta, Jean Bismuth, Alan B Lumsden, Zsolt Garami
Dissection of the internal carotid artery (ICA) accounts for 5% to 25% of ischemic strokes in young adults. We report a case of spontaneous recanalization of a traumatic ICA dissection in which carotid duplex (CDU) and transcranial color-coded duplex ultrasound (TCCD) were used. A 47-year-old male presented with intermittent episodes of headache, blurry vision, anisocoria, and loss of taste sensation following a whiplash injury while body surfing. Magnetic resonance angiogram (MRA) of the neck revealed absent flow in the cavernous ICA and a clot at the skull base...
October 2017: Methodist DeBakey Cardiovascular Journal
https://www.readbyqxmd.com/read/29735229/drones-for-provision-of-flotation-support-in-simulated-drowning
#7
Anders Bäckman, Jacob Hollenberg, Leif Svensson, Mattias Ringh, Per Nordberg, Therese Djärv, Sune Forsberg, Olof Hernborg, Andreas Claesson
OBJECTIVE: The feasibility and potential of using drones for providing flotation devices in cases of drowning have not yet been assessed. We hypothesize that a drone carrying an inflatable life buoy is a faster way to provide flotation compared with traditional methods. The purpose of this study is to explore the feasibility and efficiency of using a drone for delivering and providing flotation support to conscious simulated drowning victims. METHODS: A simulation study was performed with a simulated drowning victim 100 m from the shore...
May 2018: Air Medical Journal
https://www.readbyqxmd.com/read/29734129/latent-profiles-of-family-background-personality-and-mental-health-factors-and-their-association-with-behavioural-addictions-and-substance-use-disorders-in-young-swiss-men
#8
Simon Marmet, Joseph Studer, Ansgar Rougemont-Bücking, Gerhard Gmel
BACKGROUND: Recent theories suggest that behavioural addictions and substance use disorders may be the result of the same underlying vulnerability. The present study investigates profiles of family background, personality and mental health factors and their associations with seven behavioural addictions (to the internet, gaming, smartphones, internet sex, gambling, exercise and work) and three substance use disorder scales (for alcohol, cannabis and tobacco). METHODS: The sample consisted of 5287 young Swiss men (mean age = 25...
May 4, 2018: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/29732340/new-pseudo-ct-generation-approach-from-magnetic-resonance-imaging-using-a-local-texture-descriptor
#9
H Chaibi, R Nourine
Background: One of the challenges of PET/MRI combined systems is to derive an attenuation map to correct the PET image. For that, the pseudo-CT image could be used to correct the attenuation. Until now, most existing scientific researches construct this pseudo-CT image using the registration techniques. However, these techniques suffer from the local minima of the non-rigid deformation energy function which leads to unsatisfactory results. Objective: We propose in this paper a new approach for the generation of a pseudo-CT image from an MR image...
March 2018: Journal of Biomedical Physics & Engineering
https://www.readbyqxmd.com/read/29728248/determining-anxiety-in-obsessive-compulsive-disorder-through-behavioural-clustering-and-variations-in-repetition-intensity
#10
Conor Cameron, Ibrahim Khalil, David Castle
BACKGROUND AND OBJECTIVES: Over the last decade, the application of computer vision techniques to the analysis of behavioural patterns has seen a considerable increase in research interest. One such interesting and recent application is the visual behavioural analysis of mental disorders. Despite the very recent surge in interest in this area, relatively little has been done thus far to assist individuals living with Obsessive Compulsive Disorder. The work proposed herein represents a proof of concept system designed to demonstrate the efficacy of such an approach, from the computational perspective...
July 2018: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/29719346/the-relationship-between-the-lifestyle-of-the-elderly-in-shanghai-communities-and-mild-cognitive-impairment
#11
Ning Su, Wei Li, Xia Li, Tao Wang, Minjie Zhu, Yuanyuan Liu, Yanchen Shi, Shifu Xiao
Background: Those with mild cognitive impairment (MCI) are ten times more like to develop Alzheimer's disease (AD) than the general population. MCI diagnosis and early intervention are helpful for the diagnosis and treatment of AD in its early stages, thus delaying its development and improving the quality of life for those with MCI. Aims: To analyze the relationship between the lifestyle of the elderly in Shanghai communities and mild cognitive impairment and to look for preventative lifestyle measures for the elderly with mild cognitive impairment...
December 25, 2017: Shanghai Archives of Psychiatry
https://www.readbyqxmd.com/read/29719148/a-flow-adsorption-microcalorimetry-logistic-modeling-approach-for-assessing-heterogeneity-of-bronsted-type-surfaces-application-to-pyrogenic-organic-materials
#12
Omar R Harvey, Burke C Leonce, Bruce E Herbert
Biogeochemical functioning of oxides and pyrogenic organic matter (pyOM) are greatly influenced by surface and deprotonation characteristics. We present an energetics-based, logistic modeling approach for quantifying surface homogeneity (ϕ_surf) and surface acidity (pKa, surf) for Bronsted-type surfaces. The ϕ_surf, pKa, surf and associated deprotonation behavior of pyOM were quantified across feedstock (honey mesquite-HM, pine - PI, cord grass - CG) and heat-treatment-temperatures (HTT; 200-650 oC). At HTT200, lower ϕ_surf [HM (0...
May 2, 2018: Environmental Science & Technology
https://www.readbyqxmd.com/read/29716383/invited-article-refined-analysis-of-synchrotron-radiation-for-nist-s-surf-iii-facility
#13
Eric L Shirley, Mitchell Furst, Uwe Arp
We have developed a new method for the exact calculation of synchrotron radiation for the National Institute of Standards and Technology Synchrotron Ultraviolet Radiation Facility, SURF III. Instead of using the Schwinger formula, which is only an approximation, we develop formulae based on Graf's addition theorem for Bessel functions and accurate asymptotic expansions for Hankel functions and Bessel functions. By measuring the radiation intensity profile at two distances from the storage ring, we also confirm an apparent vertical emittance that is consistent with the vertical betatron oscillations that are intentionally introduced to extend beam lifetime by spreading the electron beam spatially...
April 2018: Review of Scientific Instruments
https://www.readbyqxmd.com/read/29694429/an-effective-content-based-image-retrieval-technique-for-image-visuals-representation-based-on-the-bag-of-visual-words-model
#14
Safia Jabeen, Zahid Mehmood, Toqeer Mahmood, Tanzila Saba, Amjad Rehman, Muhammad Tariq Mahmood
For the last three decades, content-based image retrieval (CBIR) has been an active research area, representing a viable solution for retrieving similar images from an image repository. In this article, we propose a novel CBIR technique based on the visual words fusion of speeded-up robust features (SURF) and fast retina keypoint (FREAK) feature descriptors. SURF is a sparse descriptor whereas FREAK is a dense descriptor. Moreover, SURF is a scale and rotation-invariant descriptor that performs better in the case of repeatability, distinctiveness, and robustness...
2018: PloS One
https://www.readbyqxmd.com/read/29684443/modified-porcine-surfactant-enriched-by-recombinant-human-superoxide-dismutase-for-experimental-meconium-aspiration-syndrome
#15
Jana Kopincova, Pavol Mikolka, Maros Kolomaznik, Petra Kosutova, Andrea Calkovska, Daniela Mokra
AIMS: Combination of exogenous surfactant with antioxidant enzyme recombinant human superoxide dismutase (rhSOD) was tested in the treatment of experimental meconium aspiration syndrome as oxidative processes play key role in its pathogenesis. MATERIAL AND METHODS: Young New Zealand rabbits were instilled by saline (Sal group) or by meconium suspension (Mec group). Some of meconium-instilled animals were treated by surfactant alone (Surf group) or surfactant in combination with rhSOD (Surf + SOD group) and oxygen-ventilated for 5 h...
April 20, 2018: Life Sciences
https://www.readbyqxmd.com/read/29650037/open-label-randomized-multicentre-phase-ii-study-to-assess-the-efficacy-and-tolerability-of-sunitinib-by-dose-administration-regimen-dose-modification-or-dose-interruptions-in-patients-with-advanced-or-metastatic-renal-cell-carcinoma-study-protocol-of-the-surf
#16
Guillaume Mouillet, Marie-Justine Paillard, Tristan Maurina, Dewi Vernerey, Thierry Nguyen Tan Hon, Hamadi Almotlak, Ulrich Stein, Fabien Calcagno, Diane Berthod, Elise Robert, Aurelia Meurisse, Antoine Thiery-Vuillemin
BACKGROUND: Sunitinib is a tyrosine kinase inhibitor approved in the first-line metastatic renal cell carcinoma (MRCC) setting at the dose of 50 mg daily for 4 weeks followed by a pause of 2 weeks. Due to toxicity, this standard schedule (50 mg daily 4/2) can induce up to 50% of sunitinib dose modification (reduction and/or interruption). The current recommendation in such case is to reduce the dose to 37.5 mg per day (standard schedule 4/2). Recent data highlight an alternative schedule: 2 weeks of treatment followed by 1 week of pause (experimental schedule 2/1)...
April 12, 2018: Trials
https://www.readbyqxmd.com/read/29616238/development-and-validation-of-an-automated-algorithm-to-evaluate-the-abundance-of-bubbles-in-small-bowel-capsule-endoscopy
#17
Olivia Pietri, Gada Rezgui, Aymeric Histace, Marine Camus, Isabelle Nion-Larmurier, Cynthia Li, Aymeric Becq, Einas Abou Ali, Olivier Romain, Ulriikka Chaput, Philippe Marteau, Christian Florent, Xavier Dray
Background and study aims : Bubbles can impair visualization of the small bowel (SB) mucosa during capsule endoscopy (CE). We aimed to develop and validate a computed algorithm that would allow evaluation of the abundance of bubbles in SB-CE still frames. Patients and methods : Two sets of 200 SB-CE normal still frames were created. Two experienced SB-CE readers analyzed both sets of images twice, in a random order. Each still frame was categorized as presenting with < 10 % or ≥ 10 % of bubbles...
April 2018: Endoscopy International Open
https://www.readbyqxmd.com/read/29602782/kite-surfing-epidemiology-of-trauma
#18
Lisa Dunne, Evelyn Murphy, Peter Hugh Dawson, Michael Leonard
Kite surfing has become an increasingly popular recreational activity worldwide. Thrill seekers can span the water at high speeds and reach great heights risking injury and death. We report the case of a young kite surfer who sustained a fracture dislocation of the right acetabulum that required specialised surgical management. We present this case with a review of the literature outlining the incidence of pelvic and acetabular fractures in the kitesurfing community. Overall, there is a low incidence of pelvic fractures in comparison with other orthopaedic traumas reported among kite surfers, and the most commonly injured sites are the foot and ankle...
March 29, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29578869/orthopedic-injuries-in-professional-surfers-a-retrospective-study-at-a-single-orthopedic-center
#19
Eric Hohn, Sean Robinson, Jarrad Merriman, Robin Parrish, Warren Kramer
BACKGROUND: Literature regarding surfing injuries is scarce and most studies report a high number of minor injuries. Recent literature suggests that musculoskeletal injuries are more common than previously reported. In the mid 2000s, competitive surfing has seen an increase in aerial maneuvers, as they have become more highly rewarded by the judging panel, which may be contributing to a change in injury patterns. Our goal was to evaluate orthopedic injuries in professional surfers. HYPOTHESIS: Orthopedic injuries in professional surfers are diverse and have evolved with skill and technology...
March 23, 2018: Clinical Journal of Sport Medicine: Official Journal of the Canadian Academy of Sport Medicine
https://www.readbyqxmd.com/read/29576604/parental-internet-use-and-lifestyle-factors-as-correlates-of-prolonged-screen-time-of-children-in-japan-results-from-the-super-shokuiku-school-project
#20
Masaaki Yamada, Michikazu Sekine, Takashi Tatsuse
BACKGROUND: Prolonged screen time (ST), which includes TV viewing and gaming on smartphones and computers, is linked to poor health. Our aim was to explore the associations between school children with prolonged ST and parental internet use (IU) and lifestyles in Japan. METHODS: Children aged 6 to 13 years from the Super Shokuiku School Project, were surveyed using questionnaires in 2016. The survey assessed the grade, sex, and lifestyle of 1,659 children and parental internet use (IU) and lifestyle using Breslow's seven health behaviors...
March 24, 2018: Journal of Epidemiology
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