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https://www.readbyqxmd.com/read/28334431/intentionality-in-frontal-asymmetry-research
#1
Johannes Hewig
The present article provides a theoretical viewpoint on several aspects in frontal asymmetry research. Based on a brief overview of evidence related to an approach-avoidance perspective and the relation to BIS-BAS models on frontal asymmetry I propose that intentionality is valuable to understanding frontal asymmetry. In particular, I argue that defining arguments and previous experimental research often focused on a phase of human action that may be denoted as a volitional phase, which is linked to intentions...
March 23, 2017: Psychophysiology
https://www.readbyqxmd.com/read/28333931/differential-gene-expression-in-patients-with-subsyndromal-symptomatic-depression-and-major-depressive-disorder
#2
Chengqing Yang, Guoqin Hu, Zezhi Li, Qingzhong Wang, Xuemei Wang, Chengmei Yuan, Zuowei Wang, Wu Hong, Weihong Lu, Lan Cao, Jun Chen, Yong Wang, Shunying Yu, Yimin Zhou, Zhenghui Yi, Yiru Fang
BACKGROUND: Subsyndromal symptomatic depression (SSD) is a subtype of subthreshold depressive and can lead to significant psychosocial functional impairment. Although the pathogenesis of major depressive disorder (MDD) and SSD still remains poorly understood, a set of studies have found that many same genetic factors play important roles in the etiology of these two disorders. Nowadays, the differential gene expression between MDD and SSD is still unknown. In our previous study, we compared the expression profile and made the classification with the leukocytes by using whole-genome cRNA microarrays among drug-free first-episode subjects with SSD, MDD and matched healthy controls (8 subjects in each group), and finally determined 48 gene expression signatures...
2017: PloS One
https://www.readbyqxmd.com/read/28332121/impairment-in-emotion-perception-from-body-movements-in-individuals-with-bipolar-i-and-bipolar-ii-disorder-is-associated-with-functional-capacity
#3
Anja Vaskinn, Trine Vik Lagerberg, Thomas D Bjella, Carmen Simonsen, Ole A Andreassen, Torill Ueland, Kjetil Sundet
BACKGROUND: Individuals with bipolar disorder present with moderate impairments in social cognition during the euthymic state. The impairment extends to theory of mind and to the perception of emotion in faces and voices, but it is unclear if emotion perception from body movements is affected. The main aim of this study was to examine if participants with bipolar disorder perform worse than healthy control participants on a task using point-light displays of human full figures moving in a manner indicative of a basic emotion (angry, happy, sad, fearful, neutral/no emotion)...
December 2017: International Journal of Bipolar Disorders
https://www.readbyqxmd.com/read/28327446/adherence-to-dietary-recommendations-is-not-associated-with-depression-in-two-swiss-population-based-samples
#4
Aline Richard, Sabine Rohrmann, Caroline L Vandeleur, Aurélie M Lasserre, Marie-Pierre F Strippoli, Monika Eichholzer, Jennifer Glaus, Pedro Marques-Vidal, Peter Vollenweider, Martin Preisig
Little is known about adherence to dietary recommendations and depression. Furthermore, dietary habits may differ among depression subtypes, which has not been evaluated previously. Two population-based Swiss studies, including 3620 individuals from PsyCoLaus and 11,032 individuals from the Swiss Health Survey 2012 (SHS), were used to examine the associations between adherence to common dietary guidelines and odds of depressive disorders. In both studies, depression was assessed by validated instruments. Adherence to dietary recommendations were assessed by a semi-quantitative food frequency questionnaire (PsyCoLaus) and by single item questions (SHS)...
March 9, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28327097/rumination-mediates-the-relationship-between-overgeneral-autobiographical-memory-and-depression-in-patients-with-major-depressive-disorder
#5
Yansong Liu, Xinnian Yu, Bixiu Yang, Fuquan Zhang, Wenhua Zou, Aiguo Na, Xudong Zhao, Guangzhong Yin
BACKGROUND: Overgeneral autobiographical memory has been identified as a risk factor for the onset and maintenance of depression. However, little is known about the underlying mechanisms that might explain overgeneral autobiographical memory phenomenon in depression. The purpose of this study was to test the mediation effects of rumination on the relationship between overgeneral autobiographical memory and depressive symptoms. Specifically, the mediation effects of brooding and reflection subtypes of rumination were examined in patients with major depressive disorder...
March 21, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28323538/relationships-between-a-dissociative-subtype-of-ptsd-and-clinical-characteristics-in-patients-with-substance-use-disorders
#6
Michaela Mergler, Martin Driessen, Ursula Havemann-Reinecke, Dirk Wedekind, Christel Lüdecke, Martin Ohlmeier, Claudia Chodzinski, Sybille Teunißen, Steffen Weirich, Detlef Schläfke, Walter Renner, Ingo Schäfer, Gertrud Koesters, Christian Dette, Olaf Reis, Elisabeth H Sylvester, Martin Hoppe, Markus Stuppe, Thomas Broese, Udo Schneider, Christina Pletke
The increasing support for a dissociative subtype of post-traumatic stress disorder (PTSD-D) has led to its inclusion in DSM-5. We examined relationships between PTSD-D and relevant variables in patients with substance use disorders (SUD). The sample comprised N = 459 patients with SUD. The International Diagnostic Checklist and the Posttraumatic Diagnostic Scale were used to diagnose PTSD. In addition, participants completed the Childhood Trauma Questionnaire and the Dissociative Experiences Scale. The course of SUD was assessed by means of the European Addiction Severity Index...
March 21, 2017: Journal of Psychoactive Drugs
https://www.readbyqxmd.com/read/28319689/using-a-hybrid-subtyping-model-to-capture-patterns-and-dimensionality-of-depressive-and-anxiety-symptomatology-in-the-general-population
#7
Klaas J Wardenaar, Rob B K Wanders, Margreet Ten Have, Ron de Graaf, Peter de Jonge
BACKGROUND: Researchers have tried to identify more homogeneous subtypes of major depressive disorder (MDD) with latent class analyses (LCA). However, this approach does no justice to the dimensional nature of psychopathology. In addition, anxiety and functioning-levels have seldom been integrated in subtyping efforts. Therefore, this study used a hybrid discrete-dimensional approach to identify subgroups with shared patterns of depressive and anxiety symptomatology, while accounting for functioning-levels...
March 14, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28315937/gender-differences-in-subtypes-of-depression-by-first-incidence-and-age-of-onset-a-follow-up-of-the-lundby-population
#8
Mats Bogren, L Brådvik, C Holmstrand, L Nöbbelin, C Mattisson
The Lundby Study is a prospective mental health survey in a community population (N = 3563), in which data were collected in 4 waves of field-work between 1947 and 1997. We investigated gender differences during the follow-up in overall first incidence rates, ages of onset, and incidence by age of onset patterns, in different subtypes of depression. The overall incidence rate in females was higher than males for most subtypes of depression. However, for depression with melancholic and/or psychotic features, the overall first incidence rate did not differ significantly between the genders...
March 18, 2017: European Archives of Psychiatry and Clinical Neuroscience
https://www.readbyqxmd.com/read/28315845/icarus-study-prevalence-and-clinical-features-of-impulse-control-disorders-in-parkinson-s-disease
#9
Angelo Antonini, Paolo Barone, Ubaldo Bonuccelli, Karin Annoni, Mahnaz Asgharnejad, Paolo Stanzione
BACKGROUND: Impulse control disorders/other compulsive behaviours ('ICD behaviours') occur in Parkinson's disease (PD), but prospective studies are scarce, and prevalence and clinical characteristics of patients are insufficiently defined. OBJECTIVES: To assess the presence of ICD behaviours over a 2-year period, and evaluate patients' clinical characteristics. METHODS: A prospective, non-interventional, multicentre study (ICARUS (Impulse Control disorders And the association of neuRopsychiatric symptoms, cognition and qUality of life in ParkinSon disease); SP0990) in treated Italian PD outpatients...
April 2017: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/28301432/patient-reported-outcomes-of-quality-of-life-functioning-and-gi-psychiatric-symptom-severity-in-patients-with-inflammatory-bowel-disease-ibd
#10
Waguih W IsHak, Dana Pan, Alexander J Steiner, Edward Feldman, Amy Mann, James Mirocha, Itai Danovitch, Gil Y Melmed
BACKGROUND: Patients with inflammatory bowel disease (IBD) are at risk for psychiatric disorders that impact symptom experience and health-related quality of life (HRQOL). Therefore, comprehensive biopsychosocial assessments should be considered in ambulatory care settings. Patient-Reported Outcomes Measurement Information System (PROMIS) measures created by the National Institutes of Health have shown construct validity in a large IBD internet-based cohort, but their validity in ambulatory settings has not been examined...
March 15, 2017: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/28293112/new-opinion-on-the-subtypes-of-poststroke-depression-in-chinese-stroke-survivors
#11
Yingying Yue, Rui Liu, Yin Cao, Yanfeng Wu, Shining Zhang, Huajie Li, Jijun Zhu, Wenhao Jiang, Aiqin Wu, Yonggui Yuan
AIM: Poststroke depression (PSD) is the most common complication of stroke. However, some stroke survivors with depression cannot meet the diagnostic criteria of PSD. The aim of this study was to propose the new conception of stroke patients with depression and then make them to receive reasonable diagnosis and treatment. METHODS: We first put forward the opinion that the general PSD should consist of PSD disorder (PSDD) and PSD symptoms (PSDS) according to the Diagnostic and Statistical Manual of Mental Disorder - Fifth Edition (DSM-5) and ZhongDa diagnostic criteria - first edition (ZD-1), respectively...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/28284346/ampa-nmda-and-kainate-glutamate-receptor-subunits-are-expressed-in-human-peripheral-blood-mononuclear-cells-pbmcs-where-the-expression-of-gluk4-is-altered-by-pregnancy-and-glun2d-by-depression-in-pregnant-women
#12
Amol K Bhandage, Zhe Jin, Charlotte Hellgren, Sergiy V Korol, Krzysztof Nowak, Louise Williamsson, Inger Sundström-Poromaa, Bryndis Birnir
The amino acid glutamate opens cation permeable ion channels, the iGlu receptors. These ion channels are abundantly expressed in the mammalian brain where glutamate is the main excitatory neurotransmitter. The neurotransmitters and their receptors are being increasingly detected in the cells of immune system. Here we examined the expression of the 18 known subunits of the iGlu receptors families; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA), kainate, N-methyl-d-aspartate (NMDA) and delta in human peripheral blood mononuclear cells (PBMCs)...
April 15, 2017: Journal of Neuroimmunology
https://www.readbyqxmd.com/read/28284107/clinical-characteristics-and-treatment-outcomes-of-patients-with-major-depressive-disorder-and-comorbid-anxiety-disorders-results-from-a-european-multicenter-study
#13
Markus Dold, Lucie Bartova, Daniel Souery, Julien Mendlewicz, Alessandro Serretti, Stefano Porcelli, Joseph Zohar, Stuart Montgomery, Siegfried Kasper
This naturalistic European multicenter study aimed to elucidate the association between major depressive disorder (MDD) and comorbid anxiety disorders. Demographic and clinical information of 1346 MDD patients were compared between those with and without concurrent anxiety disorders. The association between explanatory variables and the presence of comorbid anxiety disorders was examined using binary logistic regression analyses. 286 (21.2%) of the participants exhibited comorbid anxiety disorders, 10.8% generalized anxiety disorder (GAD), 8...
February 27, 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/28281967/inhibition-of-proliferation-migration-and-invasion-by-knockdown-of-pyruvate-kinase-m2-pkm2-in-ovarian-cancer-skov3-and-ovcar3-cells
#14
Yi Miao, Meng Lu, Qin Yan, Shuangdi Li, Youji Feng
Pyruvate kinase (PK) is a key enzyme in the process of glycolysis, catalyzing phosphoenolpyruvate (PEP) into pyruvate. Currently, PK isozyme type M2 (PKM2), one subtype of PK, has been proposed as a new tumor marker with high expression in various tumor tissues. Here we aimed to explore the effects of siRNA-PKM2 on ovarian carcinoma (OC) cell lines SKOV3 and OVCAR3, in which PKM2 was notably expressed. PKM2 gene interference lentivirus vectors were built by miRNA transfection assay. siRNA-PKM2-transfected SKOV3 and OVCAR3 cells were evaluated for cell proliferation, cell cycle distribution, cell apoptosis, cell migration, and invasion in this study...
October 27, 2016: Oncology Research
https://www.readbyqxmd.com/read/28275829/endothelial-nitric-oxide-synthase-in-rat-brain-is-downregulated-by-sub-chronic-antidepressant-treatment
#15
Yuta Yoshino, Shinichiro Ochi, Kiyohiro Yamazaki, Shunsuke Nakata, Jun-Ichi Iga, Shu-Ichi Ueno
BACKGROUND: Nitric oxide (NO) is a neurotransmitter that may be related to major depressive disorder (MDD) because the selective neuronal NO synthase (NOS) inhibitor, 7-nitroindazole, induces a dose-dependent antidepressant-like effect. NO modulates major neurotransmitters involved in the neurobiology of MDD, such as norepinephrine, serotonin, dopamine, and glutamate. In this study, we investigated the effects of antidepressants as NO modulators in acute and sub-chronic treatments. METHODS: Rats were injected with the SSRI paroxetine (PAR, 10 mg/kg), the SNRI milnacipran (MIL, 30 mg/kg), or the NaSSA mirtazapine (MIR, 10 mg/kg) for acute (1 h) or sub-chronic (3 weeks) treatment prior to analysis of nine brain regions (frontal cortex, temporal cortex, striatum, thalamus, hippocampus, midbrain, pons, cerebellum, and olfactory bulb)...
March 8, 2017: Psychopharmacology
https://www.readbyqxmd.com/read/28274920/h2o2-augments-cytosolic-calcium-in-nucleus-tractus-solitarii-neurons-via-multiple-voltage-gated-calcium-channels
#16
Tim D Ostrowski, Heather A Dantzler, Luis Polo-Parada, David D Kline
Reactive oxygen species (ROS) play a profound role in cardiorespiratory function under normal physiological conditions and disease states. ROS can influence neuronal activity by altering various ion channels and transporters. Within the nucleus tractus solitarii (nTS), a vital brainstem area for cardiorespiratory control, hydrogen peroxide (H2O2) induces sustained hyperexcitability following an initial depression of neuronal activity. The mechanism(s) associated with the delayed hyperexcitability are unknown...
March 8, 2017: American Journal of Physiology. Cell Physiology
https://www.readbyqxmd.com/read/28273521/positive-future-oriented-fantasies-and-depressive-symptoms-indirect-relationship-through-brooding
#17
Natalia Macrynikola, Shama Goklani, Julia Slotnick, Regina Miranda
Although a positive future outlook is generally associated with psychological well-being, indulging in positive fantasies about the future has been found to exacerbate negative mood-related outcomes such as depressive symptoms. We examined rumination as a cognitive mechanism in this relationship, using an objectively coded measure of future-oriented fantasies, among 261 young adults assessed twice. Engaging in a positive fantasy about the future was associated with the brooding subtype of rumination but not with reflection at baseline...
March 4, 2017: Consciousness and Cognition
https://www.readbyqxmd.com/read/28267062/allodynia-in-cluster-headache
#18
Leopoldine A Wilbrink, Mark A Louter, Onno Pm Teernstra, Erik W van Zwet, Frank Jpm Huygen, Joost Haan, Michel D Ferrari, Gisela M Terwindt
Cutaneous allodynia is an established marker for central sensitization in migraine. There is debate whether cutaneous allodynia may also occur in cluster headache, another episodic headache disorder. Here we examined the presence and severity of allodynia in a large well-defined nation-wide population of people with cluster headache.Using validated questionnaires we assessed, cross-sectionally, ictal allodynia and comorbid depression and migraine in the nation-wide "Leiden University Cluster headache neuro-Analysis" (LUCA) study...
March 4, 2017: Pain
https://www.readbyqxmd.com/read/28260234/affect-lability-predicts-occurrence-of-suicidal-ideation-in-bipolar-patients-a-two-year-prospective-study
#19
D Ducasse, I Jaussent, S Guillaume, J M Azorin, F Bellivier, R Belzeaux, T Bougerol, B Etain, S Gard, C Henry, J P Kahn, M Leboyer, J Loftus, C Passerieux, E Olié, P Courtet
OBJECTIVE: The aim of our study was to investigate, in bipolar patients, whether affect lability was associated with suicidal ideation incidence during 2-year follow-up, and which subtype of affect lability was associated with suicidal ideation. METHOD: A total of 319 euthymic or mildly depressed bipolar outpatients recruited in the French FondaMental Advanced Centres of Expertise for Bipolar Disorder were divided into two subgroups according to the occurrence of suicidal ideation during a 2-year follow-up...
March 5, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/28257825/association-between-c-reactive-protein-crp-with-depression-symptom-severity-and-specific-depressive-symptoms-in-major-depression
#20
Ole Köhler-Forsberg, Henriette N Buttenschøn, Katherine E Tansey, Wolfgang Maier, Joanna Hauser, Mojca Zvezdana Dernovsek, Neven Henigsberg, Daniel Souery, Anne Farmer, Marcella Rietschel, Peter McGuffin, Katherine J Aitchison, Rudolf Uher, Ole Mors
INTRODUCTION: Population-based studies have associated inflammation, particularly higher C-reactive protein (CRP), with depressive severity, but clinical trials in major depressive disorder were rather non-specific without examining the role of gender. We aimed to investigate the association between CRP and overall depression severity including specific depressive symptoms and to examine potential gender differences. METHODS: We included 231 individuals with major depressive disorder from the Genome-Based Therapeutics Drugs for Depression (GENDEP) study...
March 1, 2017: Brain, Behavior, and Immunity
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