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Depression subtypes

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https://www.readbyqxmd.com/read/28748306/low-emotion-oriented-coping-and-informal-help-seeking-behaviour-as-major-predictive-factors-for-improvement-in-major-depression-at-5-year-follow-up-in-the-adult-community
#1
S Rodgers, C L Vandeleur, M-P F Strippoli, E Castelao, A Tesic, J Glaus, A M Lasserre, M Müller, W Rössler, V Ajdacic-Gross, M Preisig
PURPOSE: Given the broad range of biopsychosocial difficulties resulting from major depressive disorder (MDD), reliable evidence for predictors of improved mental health is essential, particularly from unbiased prospective community samples. Consequently, a broad spectrum of potential clinical and non-clinical predictors of improved mental health, defined as an absence of current major depressive episode (MDE) at follow-up, were examined over a 5-year period in an adult community sample...
July 26, 2017: Social Psychiatry and Psychiatric Epidemiology
https://www.readbyqxmd.com/read/28742292/effects-of-a-course-of-right-unilateral-ultrabrief-pulse-electroconvulsive-therapy-combined-with-venlafaxine-on-insomnia-symptoms-in-elderly-depressed-patients
#2
W Vaughn McCall, Sarah H Lisanby, Peter B Rosenquist, Mary Dooley, Mustafa M Husain, Rebecca G Knapp, Georgios Petrides, Matthew V Rudorfer, Robert C Young, Shawn M McClintock, Martina Mueller, Joan Prudic, Robert M Greenberg, Richard D Weiner, Samuel H Bailine, Mary Anne Riley, Laryssa McCloud, Charles H Kellner
OBJECTIVE: Antidepressant medications have a variety of effects on sleep, apart from their antidepressant effects. It is unknown whether electroconvulsive therapy (ECT) has effects on perceived sleep in depressed patients. This secondary analysis examines the effects of ECT on perceived sleep, separate from its antidepressant effects. METHODS: Elderly patients with major depressive disorder, as defined by DSM-IV, received open-label high-dose, right unilateral ultrabrief pulse ECT, combined with venlafaxine, as part of participating in phase 1 of the National Institute of Mental Health-supported study Prolonging Remission in Depressed Elderly (PRIDE)...
July 18, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/28735929/electrophysiological-and-microstructural-features-of-sleep-in%C3%A2-children%C3%A2-at-high-risk-for-depression-a-preliminary-study
#3
Gianluca Sesso, Flora Bat-Pitault, Aurore Guyon, Sabine Plancoulaine, Tommaso Banfi, Giulia Milioli, Liborio Parrino, Ugo Faraguna, Patricia Franco
OBJECTIVE: This preliminary study investigated electrophysiological and microstructural features of sleep in children and adolescents 4-18 years of age who were born to depressed mothers. METHODS: A total of 31 healthy subjects (15 male and 16 female) participated in the study. In this sample, 20 children born to mothers diagnosed with Major Depressive Disorder (MDD) were designated as "high-risk"; 11 children born to mothers without a personal history of depression were designated as "low-risk...
August 2017: Sleep Medicine
https://www.readbyqxmd.com/read/28728805/associations-of-c-reactive-protein-and-psychological-distress-are-modified-by-antidepressants-supporting-an-inflammatory-depression-subtype-findings-from-ukhls
#4
Amanda Hughes, Meena Kumari
BACKGROUND: Clinical evidence increasingly suggests inflammation may be important specifically for an etiologically distinct depression subtype, characterised by resistance to antidepressant medication. However, epidemiological investigations of the relationship of inflammation with depression and psychological distress have failed to acknowledge these developments, which may have resulted in bias or masking of associations driven by the subtype. This may have contributed to inconsistent results in epidemiological studies, and equivocal support for an inflammation-depression link...
July 17, 2017: Brain, Behavior, and Immunity
https://www.readbyqxmd.com/read/28726052/transcranial-sonography-image-characteristics-in-different-parkinson-s-disease-subtypes
#5
Ai Yan Sheng, Ying Chun Zhang, Yu Jing Sheng, Cai Shan Wang, Ying Zhang, Hua Hu, Wei Feng Luo, CHun-Feng LIu
Recently, Parkinson's disease (PD) has been classified into three subtypes: postural instability gait difficulty (PIGD), tremor dominate (TD), and indeterminate PD. Transcranial sonography (TCS) is considered to be an important tool to diagnose PD. However, it is uncertain that whether there are differences in TCS image characteristics in different PD subtypes, so 373 idiopathic PD (188 PIGD, 108 TD, 77 indeterminate PD) were registered and received TCS in our investigation; also, the association between clinical characteristics and TCS results in different PD subtypes was analyzed...
July 19, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28724369/acculturation-and-other-risk-factors-of-depressive-disorders-in-individuals-with-turkish-migration-backgrounds
#6
Hanna Janssen-Kallenberg, Holger Schulz, Ulrike Kluge, Jens Strehle, Hans-Ulrich Wittchen, Uwe Wolfradt, Uwe Koch-Gromus, Andreas Heinz, Mike Mösko, Demet Dingoyan
BACKGROUND: Acculturation is a long-term, multi-dimensional process occurring when subjects of different cultures stay in continuous contact. Previous studies have suggested that elevated rates of depression among different migrant groups might be due to patterns of acculturation and migration related risk factors. This paper focused on prevalence rates of depressive disorders and related risk factors among individuals with Turkish migration backgrounds. METHODS: A population-based sample of 662 individuals with Turkish migration backgrounds were interviewed by bilingual interviewers using a standardised diagnostic interview for DSM-IV-TR and ICD-10 diagnoses (CIDI DIA-X Version 2...
July 19, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28719083/subtypes-of-personality-and-locus-of-control-in-bariatric-patients-and-their-effect-on-weight-loss-eating-disorder-and-depressive-symptoms-and-quality-of-life
#7
Carolin Peterhänsel, Katja Linde, Birgit Wagner, Arne Dietrich, Anette Kersting
The present study subdivided personality types in a bariatric sample and investigated their impact on weight loss and psychopathology 6 and 12 months after surgery. One hundred thirty participants answered questionnaires on personality (NEO-FFI), 'locus of control' (IPC), depression severity (BDI-II), eating disorder psychopathology (EDE-Q), and health-related quality of life (HRQoL; SF-12). K-means cluster analyses were used to identify subtypes. Two subtypes emerged: an 'emotionally dysregulated/undercontrolled' cluster defined by high neuroticism and external orientation and a 'resilient/high functioning' cluster with the reverse pattern...
July 18, 2017: European Eating Disorders Review: the Journal of the Eating Disorders Association
https://www.readbyqxmd.com/read/28715727/efficacy-and-safety-of-long-term-antidepressant-treatment-for-bipolar-disorders-a-meta-analysis-of-randomized-controlled-trials
#8
Bangshan Liu, Yan Zhang, Han Fang, Jin Liu, Tiebang Liu, Lingjiang Li
OBJECTIVE: Efficacy and safety of long-term use of antidepressants (AD) in bipolar disorder (BD) patients remains highly controversial. Here we performed a meta-analysis of randomized controlled trials (RCTs) exploring the efficacy and safety of long-term AD use in BD patients. METHODS: English-written literature published in peer-reviewed journal was systematically searched from Pubmed, EMBASE, CENTRAL, PsycINFO and Clinicaltrials.gov. Each database was searched from its first available time to August 31, 2016...
July 11, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28710953/partially-distinct-combinations-of-psychological-metabolic-and-inflammatory-risk-factors-are-prospectively-associated-with-the-onset-of-the-subtypes-of-major-depressive-disorder-in-midlife
#9
Dominique A Rudaz, Caroline L Vandeleur, Sirak Z Gebreab, Mehdi Gholam-Rezaee, Marie-Pierre F Strippoli, Aurélie M Lasserre, Jennifer Glaus, Enrique Castelao, Giorgio Pistis, Roland von Känel, Pedro Marques-Vidal, Gérard Waeber, Peter Vollenweider, Martin Preisig
BACKGROUND: Given the well known heterogeneity of Major Depressive Disorder (MDD), dividing this complex disorder into subtypes is likely to be a more promising approach to identify its determinants than to study it as a whole. METHODS: In a prospective population-based cohort study (CoLaus|PsyCoLaus) with 5.5 years of follow-up, 1524 participants without MDD at baseline, aged 35-66 years (mean age 51.4 years, 43.4% females), participated in the physical and psychiatric baseline and the psychiatric follow-up evaluations...
November 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28698873/epidemiological-distribution-and-subtype-analysis-of-premenstrual-dysphoric-disorder-syndromes-and-symptoms-based-on-tcm-theories
#10
Mingqi Qiao, Peng Sun, Haijun Wang, Yang Wang, Xianghong Zhan, Hongqi Liu, Xiaoyun Wang, Xia Li, Xiaoru Wang, Jibiao Wu, Fushun Wang
We performed an epidemiological investigation of subjects with premenstrual dysphoric disorder (PMDD) to identify the clinical distribution of the major syndromes and symptoms. The pathogenesis of PMDD mainly involves the dysfunction of liver conveyance and dispersion. Excessive liver conveyance and dispersion are associated with liver-qi invasion syndrome, while insufficient liver conveyance and dispersion are expressed as liver-qi depression syndrome. Additionally, a nonconditional logistic regression was performed to analyze the symptomatic features of liver-qi invasion and liver-qi depression...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28681643/sexual-functioning-in-multiple-sclerosis-relationships-with-depression-fatigue-and-physical-function
#11
Carolyn A Young, Alan Tennant
BACKGROUND: Sexual dysfunction (SD) is common among people with multiple sclerosis, but there is limited information on its relationships. OBJECTIVE: This national study examines the relationships between sexual function with demographic factors, physical function, fatigue and depression. METHODS: Participants in the Trajectories of Outcomes in Neurological Conditions (TONiC) study completed the measures of fatigue, physical function and depression together with the Multiple Sclerosis Intimacy and Sexuality Questionnaire-15 (MSISQ-15), which covers sexual function (primary), symptoms that interfere with sexual function (secondary) and psychological issues (tertiary)...
November 1, 2016: Multiple Sclerosis: Clinical and Laboratory Research
https://www.readbyqxmd.com/read/28680060/novel-oestrogen-receptor-%C3%AE-selective-ligand-reduces-obesity-and-depressive-like-behaviour-in-ovariectomized-mice
#12
Daimei Sasayama, Nobuhiro Sugiyama, Shigeru Yonekubo, Akiko Pawlak, Hiroyasu Murasawa, Mie Nakamura, Morimichi Hayashi, Takashi Ogawa, Makoto Moro, Shinsuke Washizuka, Naoji Amano, Kazuhiro Hongo, Hideki Ohnota
Hormonal changes due to menopause can cause various health problems including weight gain and depressive symptoms. Multiple lines of evidence indicate that oestrogen receptors (ERs) play a major role in postmenopausal obesity and depression. However, little is known regarding the ER subtype-specific effects on obesity and depressive symptoms. To delineate potential effects of ERβ activation in postmenopausal women, we investigated the effects of a novel oestrogen receptor β-selective ligand (C-1) in ovariectomized mice...
July 5, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28679115/sample-heterogeneity-in-unipolar-depression-as-assessed-by-functional-connectivity-analyses-is-dominated-by-general-disease-effects
#13
Stephan Feder, Benedikt Sundermann, Heike Wersching, Anja Teuber, Harald Kugel, Henning Teismann, Walter Heindel, Klaus Berger, Bettina Pfleiderer
OBJECTIVES: Combinations of resting-state fMRI and machine-learning techniques are increasingly employed to develop diagnostic models for mental disorders. However, little is known about the neurobiological heterogeneity of depression and diagnostic machine learning has mainly been tested in homogeneous samples. Our main objective was to explore the inherent structure of a diverse unipolar depression sample. The secondary objective was to assess, if such information can improve diagnostic classification...
November 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28679049/role-of-mglu5-receptors-and-inhibitory-neurotransmission-in-m1-dependent-muscarinic-ltd-in-the-prefrontal-cortex-implications-in-schizophrenia
#14
Ayan Ghoshal, Sean P Moran, Jonathan W Dickerson, Max E Joffe, Brad A Grueter, Zixiu Xiang, Craig W Lindsley, Jerri M Rook, P Jeffrey Conn
Selective potentiation of the mGlu5 subtype of metabotropic glutamate (mGlu) receptor using positive allosteric modulators (PAMs) has robust cognition-enhancing effects in rodent models that are relevant for schizophrenia. Until recently, these effects were thought to be due to potentiation of mGlu5-induced modulation of NMDA receptor (NMDAR) currents and NMDAR-dependent synaptic plasticity. However, "biased" mGlu5 PAMs that do not potentiate mGlu5 effects on NMDAR currents show efficacy that is similar to that of prototypical mGlu5 PAMs, suggesting that NMDAR-independent mechanisms must be involved in these actions...
July 5, 2017: ACS Chemical Neuroscience
https://www.readbyqxmd.com/read/28675390/modifiable-predictors-of-depression-following-childhood-maltreatment-a-systematic-review-and-meta-analysis
#15
E C Braithwaite, R M O'Connor, M Degli-Esposti, N Luke, L Bowes
Although maltreatment experiences in childhood increase the risk for depression, not all maltreated children become depressed. This review aims to systematically examine the existing literature to identify modifiable factors that increase vulnerability to, or act as a buffer against, depression, and could therefore inform the development of targeted interventions. Thirteen databases (including Medline, PsychINFO, SCOPUS) were searched (between 1984 and 2014) for prospective, longitudinal studies published in English that included at least 300 participants and assessed associations between childhood maltreatment and later depression...
July 4, 2017: Translational Psychiatry
https://www.readbyqxmd.com/read/28672433/the-increased-level-of-depression-and-anxiety-in-irritable-bowel-syndrome-patients-compared-with-healthy-controls-systematic-review-and-meta-analysis
#16
REVIEW
Changhyun Lee, Eunyoung Doo, Ji Min Choi, Seung-Ho Jang, Han-Seung Ryu, Ju Yup Lee, Jung Hwan Oh, Jung Ho Park, Yong Sung Kim
Background/Aims: Irritable bowel syndrome (IBS) patients commonly experience psychiatric disorders, such as depression and anxiety. This meta-analysis sought to compare depression and anxiety levels between IBS patients and healthy controls. Methods: We searched major electronic databases (PubMed, EMBASE, MEDLINE, and Cochrane library) to find comparative studies on IBS patients and healthy controls. The primary outcome was a standardized mean difference (SMD) of anxiety and depression levels; sub-group analyses were conducted according to IBS-subtypes...
July 30, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28671338/mixture-model-analysis-identifies-irritable-bowel-syndrome-subgroups-characterised-by-specific-profiles-of-gastrointestinal-extraintestinal-somatic-and-psychological-symptoms
#17
A Polster, L Van Oudenhove, M Jones, L Öhman, H Törnblom, M Simrén
BACKGROUND: Current subgrouping of Irritable Bowel Syndrome (IBS) is exclusively based on stool consistency without considering other relevant gastrointestinal (GI), extraintestinal somatic or psychological features. AIM: To identify subgroups based on a comprehensive set of IBS-related parameters. METHODS: Mixture model analysis was used, with the following input variables: 13 single-item scores from the IBS-specific Gastrointestinal Symptom Rating Scale, average stool consistency and frequency from a 7-day Bristol Stool Form diary, 12 single-item extraintestinal symptom scores from the Patient Health Questionnaire-12, and anxiety and depression subscale scores from the Hospital Anxiety and Depression scale...
July 3, 2017: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/28668949/naringin-reverses-neurobehavioral-and-biochemical-alterations-in-intracerebroventricular-collagenase-induced-intracerebral-hemorrhage-in-rats
#18
Navdeep Singh, Yashika Bansal, Ranjana Bhandari, Lovish Marwaha, Raghunath Singh, Kanwaljit Chopra, Anurag Kuhad
Intracerebral hemorrhage (ICH) contributes to 10-15% of all strokes and is a high risk factor for morbidity and mortality as compared to other subtypes of stroke, that is, cerebral ischemia and subarachnoid hemorrhage. Oxidative stress (OS)-induced neuroinflammation and neuronal cell death contribute towards the hallmarks of ICH. Spared antioxidant levels, increased inflammatory cytokines and free radicals in ICH lead to neuronal death and exaggerate the hallmarks of ICH. Intracerebroventricular (ICV) collagenase (COL-induced neuronal cell damage and cognitive deficits form a widely recognized experimental model for ICH...
July 1, 2017: Pharmacology
https://www.readbyqxmd.com/read/28662343/effect-of-chronic-%C3%AE-hydroxybutyrate-ghb-administration-on-ghb-toxicokinetics-and-ghb-induced-respiratory-depression
#19
Bridget L Morse, Gurkishan S Chadha, Melanie A Felmlee, Kristin E Follman, Marilyn E Morris
BACKGROUND: γ-hydroxybutyrate (GHB) has a high potential for illicit use; overdose of this compound results in sedation, respiratory depression and death. Tolerance to the hypnotic/sedative and electroencephalogram effects of GHB occurs with chronic GHB administration; however, tolerance to respiratory depression has not been evaluated. GHB toxicodynamic effects are mediated predominantly by GABAB receptors. Chronic treatment may affect monocarboxylate transporters (MCTs) and alter the absorption, renal clearance and brain uptake of GHB...
June 29, 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28656885/social-cognition-abilities-in-patients-with-different-multiple-sclerosis-subtypes
#20
Audrey Henry, Ayman Tourbah, Marie-Pierre Chaunu, Serge Bakchine, Michèle Montreuil
OBJECTIVES: Multiple sclerosis (MS) can be associated with impaired social cognition. However, social cognition skills have never been explored in the different subtypes of MS. The first aim of this study was to examine whether MS subtypes differ on the course of social cognition. The second aim was to explore the relationship between social cognition performances and executive abilities and mood variables. METHODS: Sixty-two patients with MS and 33 healthy matched controls performed experimental tasks assessing facial emotion recognition, theory of mind (ToM), and cognitive functioning, in particular executive functions...
June 28, 2017: Journal of the International Neuropsychological Society: JINS
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