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https://www.readbyqxmd.com/read/27923553/anxiety-and-depression-in-caregivers-of-individuals-with-celiac-disease-a-population-based-study
#1
Jonas F Ludvigsson, Abhik Roy, Benjamin Lebwohl, Peter H R Green, Louise Emilsson
BACKGROUND & AIMS: Partner burden is common in celiac disease (CD), but it is unclear if parents of children with CD have increased burden, and if this may translate into depression and anxiety meriting healthcare. METHODS: Nationwide population-based study of 41,753 parents and spouses ("caregivers") to 29,096 celiac patients and 215,752 caregivers to 144,522 matched controls. Caregivers were identified from the Swedish Total Population Register, and linked to data on psychiatric disease in the National Patient Registry...
November 16, 2016: Digestive and Liver Disease
https://www.readbyqxmd.com/read/27920534/perceptions-and-impact-of-bipolar-disorder-in-japan-results-of-an-internet-survey
#2
Koichiro Watanabe, Eiji Harada, Takeshi Inoue, Yuka Tanji, Toshiaki Kikuchi
Bipolar disorder is a recurrent and episodic illness. This survey study assessed experiences and identified clinical insights of individuals with bipolar disorder. An Internet-based monitor system database was screened for patients with bipolar disorder in Japan (February and March 2013). Of 1,050 patients, 457 completed surveys, and results were analyzed with descriptive statistics. Approximately one-fourth of respondents were diagnosed with bipolar disorder on their first visit to medical institutions, although the most common initial diagnosis was depression/depressive state (65%)...
2016: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/27919751/less-head-motion-during-mri-under-task-than-resting-state-conditions
#3
Willem Huijbers, Koene R A Van Dijk, Meta M Boenniger, Rüdiger Stirnberg, Monique M B Breteler
Head motion reduces data quality of neuroimaging data. In three functional magnetic resonance imaging (MRI) experiments we demonstrate that people make less head movements under task than resting-state conditions. In Experiment 1, we observed less head motion during a memory encoding task than during the resting-state condition. In Experiment 2, using publicly shared data from the UCLA Consortium for Neuropsychiatric Phenomics LA5c Study, we again found less head motion during several active task conditions than during a resting-state condition, although some task conditions also showed comparable motion...
December 2, 2016: NeuroImage
https://www.readbyqxmd.com/read/27895505/evaluating-increased-resource-use-in-fibromyalgia-using-electronic-health-records
#4
Jay M Margolis, Elizabeth T Masters, Joseph C Cappelleri, David M Smith, Steven Faulkner
OBJECTIVE: The management of fibromyalgia (FM), a chronic musculoskeletal disease, remains challenging, and patients with FM are often characterized by high health care resource utilization. This study sought to explore potential drivers of all-cause health care resource utilization and other factors associated with high resource use, using a large electronic health records (EHR) database to explore data from patients diagnosed with FM. METHODS: This was a retrospective analysis of de-identified EHR data from the Humedica database...
2016: ClinicoEconomics and Outcomes Research: CEOR
https://www.readbyqxmd.com/read/27894372/affective-lability-mediates-the-association-between-childhood-trauma-and-suicide-attempts-mixed-episodes-and-co-morbid-anxiety-disorders-in-bipolar-disorders
#5
M Aas, C Henry, F Bellivier, M Lajnef, S Gard, J-P Kahn, T V Lagerberg, S R Aminoff, T Bjella, M Leboyer, O A Andreassen, I Melle, B Etain
BACKGROUND: Many studies have shown associations between a history of childhood trauma and more severe or complex clinical features of bipolar disorders (BD), including suicide attempts and earlier illness onset. However, the psychopathological mechanisms underlying these associations are still unknown. Here, we investigated whether affective lability mediates the relationship between childhood trauma and the severe clinical features of BD. METHOD: A total of 342 participants with BD were recruited from France and Norway...
November 29, 2016: Psychological Medicine
https://www.readbyqxmd.com/read/27889599/patatin-like-phospholipase-domain-containing-protein-3-pnpla3-a-potential-role-in-the-association-between-liver-disease-and-bipolar-disorder
#6
Aileen Kenneson, Jennifer S Funderburk
OBJECTIVE: Due to the increased prevalence of liver disease in patients with bipolar disorder, we examined the potential role of the patatin-like phospholipase domain-containing protein 3 (PNPLA3) variant among individuals with bipolar disorder and those with no mood disorder. METHODS: We used the National Health and Nutrition Examination Survey (NHANES) database (aged 15-39 years) to identify a group of individuals with a bipolar diagnosis and a control group of individuals with no mood disorder...
November 22, 2016: Journal of Affective Disorders
https://www.readbyqxmd.com/read/27888379/medical-co-morbidities-among-patients-with-severe-mental-illnesses-in-a-community-health-facility-in-nigeria
#7
Victor Olufolahan Lasebikan, Joachim Azegbeobor
To examine prevalence of medical comorbidity (MCM) in schizophrenia (n = 1310) and in bipolar disorder (n = 1307) and the association of high burden of MCM (≥3 MCM) with duration of untreated illness, number of episodes, functioning, poly-medication and lifetime hospitalization for the mental disorder. Participants were recruited from a private psychiatric facility in Ibadan, Nigeria between 2004 and 2013 and enquiry made about the lifetime occurrence of 20 common chronic diseases including common tropical diseases...
November 25, 2016: Community Mental Health Journal
https://www.readbyqxmd.com/read/27887740/outcomes-of-renal-transplantation-in-patients-with-bipolar-affective-disorder-and-schizophrenia-a-national-retrospective-cohort-study
#8
Mary I Butler, Deirdre McCartan, Anne Cooney, Patrick O Kelly, Izhar Ahmed, Dilly Little, Siobhan MacHale, Peter Conlon
BACKGROUND: Patients with severe psychiatric disorders such as schizophrenia and bipolar affective disorder (BPAD) have in the past been excluded from organ transplantation programs based on their psychiatric illness. However, there is little data on the outcomes of renal transplantation in these patients and little evidence to support such exclusion. METHODS: We reviewed the database of the Irish National Renal Transplant Programme and identified all patients with a history of BPAD or schizophrenia who had received a transplant over a 28-year period...
September 20, 2016: Psychosomatics
https://www.readbyqxmd.com/read/27877043/polycystic-ovary-syndrome-and-mental-disorders-a-systematic-review-and-exploratory-meta-analysis
#9
REVIEW
Sergio Luís Blay, João Vicente Augusto Aguiar, Ives Cavalcante Passos
BACKGROUND: The association between depression, anxiety, and polycystic ovary syndrome (PCOS) is still unclear. Therefore, a systematic review and meta-analysis was conducted to assess the rates of comorbid psychiatric disorders among women with PCOS compared to women without it. METHODS: PubMed/MEDLINE, Embase, PsycINFO, and Web of Science databases were searched from inception to November 27, 2015. Studies were eligible for inclusion if they were original reports in which the rates of mood (bipolar disorder, dysthymia, or major depressive disorder), obsessive-compulsive spectrum disorders, trauma- and stressor-related disorders, anxiety disorders or psychotic disorders, somatic symptom and related disorders, or eating disorders had been investigated among women with an established diagnosis of PCOS and compared with women without PCOS...
2016: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/27872683/safe-and-effective-sofosbuvir-based-therapy-in-patients-with-mental-health-disease-on-hepatitis-c-virus-treatment
#10
Lydia Shuk Yee Tang, Jack Masur, Zayani Sims, Amy Nelson, Anu Osinusi, Anita Kohli, Sarah Kattakuzhy, Michael Polis, Shyam Kottilil
AIM: To study impact of baseline mental health disease on hepatitis C virus (HCV) treatment; and Beck's Depression Inventory (BDI) changes with sofosbuvir- and interferon-based therapy. METHODS: This is a retrospective cohort study of participants from 5 studies enrolled from single center trials conducted at the Clinical Research Center of the National Institutes of Health, Bethesda, MD, United States. All participants were adults with chronic HCV genotype 1 infection and naïve to HCV therapy...
November 8, 2016: World Journal of Hepatology
https://www.readbyqxmd.com/read/27867834/neurobiology-of-risk-for-bipolar-disorder
#11
REVIEW
Ayşegül Özerdem, Deniz Ceylan, Güneş Can
Bipolar disorder (BD) is a chronic mental illness which follows a relapsing and remitting course and requires lifetime treatment. The lack of biological markers for BD is a major difficulty in clinical practice. Exploring multiple endophenotypes to fit in multivariate genetic models for BD is an important element in the process of finding tools to facilitate early diagnosis, early intervention, prevention of new episodes, and follow-up of treatment response in BD. Reviewing of studies on neuroimaging, neurocognition, and biochemical parameters in populations with high genetic risk for the illness can yield an integrative perspective on the neurobiology of risk for BD...
2016: Current Treatment Options in Psychiatry
https://www.readbyqxmd.com/read/27863313/an-examination-of-sleep-quality-in-veterans-with-a-dual-diagnosis-of-ptsd-and-severe-mental-illness
#12
Wilson J Brown, Allison K Wilkerson, Melissa E Milanak, Peter W Tuerk, Thomas W Uhde, Bernadette M Cortese, Anouk L Grubaugh
Poor sleep quality is one of the most frequently reported symptoms by veterans with Posttraumatic Stress Disorder (PTSD) and by veterans with severe mental illness (SMI; i.e., schizophrenia spectrum disorders, bipolar disorder, major depression with or without psychotic features). However, little is known about the compounding effects of co-occurring PTSD/SMI on sleep quality in this population. Given the high rates of comorbidity and poor functional outcomes associated with sleep dysfunction, there is a need to better understand patterns of poor sleep quality in this population...
September 30, 2016: Psychiatry Research
https://www.readbyqxmd.com/read/27847931/depression-with-atypical-features-in-various-kinds-of-affective-disorders
#13
Grzegorz Buzuk, Dorota Łojko, Maciej Owecki, Marek Ruchała, Janusz Rybakowski
OBJECTIVES: Assessment of atypical symptoms in various types of depressive disorders, using the author's questionnaire for symptoms of atypical depression. METHODS: The study involved 70 patients with a diagnosis of depressive episode in the course of recurrent depression, 54 patients with a diagnosis of depressive episode in bipolar disorder (BD) and 58 patients with a diagnosis of dysthymia. To assess the severity of atypical symptoms, the special questionnaire has been elaborated...
2016: Psychiatria Polska
https://www.readbyqxmd.com/read/27847227/neuropsychological-characteristics-of-child-and-adolescent-offspring-of-patients-with-schizophrenia-or-bipolar-disorder
#14
Elena de la Serna, Gisela Sugranyes, Vanessa Sanchez-Gistau, Elisa Rodriguez-Toscano, Immaculada Baeza, Montserrat Vila, Soledad Romero, Teresa Sanchez-Gutierrez, Mª José Penzol, Dolores Moreno, Josefina Castro-Fornieles
BACKGROUND: Schizophrenia (SZ) and bipolar disorder (BD) are considered neurobiological disorders which share some clinical, cognitive and neuroimaging characteristics. Studying child and adolescent offspring of patients diagnosed with bipolar disorder (BDoff) or schizophrenia (SZoff) is regarded as a reliable method for investigating early alterations and vulnerability factors for these disorders. This study compares the neuropsychological characteristics of SZoff, BDoff and a community control offspring group (CC) with the aim of examining shared and differential cognitive characteristics among groups...
November 12, 2016: Schizophrenia Research
https://www.readbyqxmd.com/read/27846411/binge-eating-disorder-and-bipolar-spectrum-disorders-in-obesity-psychopathological-and-eating-behaviors-differences-according-to-comorbidities
#15
Cristina Segura-Garcia, Mariarita Caroleo, Marianna Rania, Elvira Barbuto, Flora Sinopoli, Matteo Aloi, Franco Arturi, Pasquale De Fazio
BACKGROUND: Obesity is not a mental disorder, yet DSM-5 recognizes a strong association between obesity and psychiatric syndromes. Disorders within the Bipolar Spectrum (BSD) and Binge Eating Disorder (BED) are the most frequent psychiatric disorders among obese patients. The aim of this research is to investigate the psychopathological differences and the distinctive eating behaviors that accompany these comorbidities in obese patients. METHODS: One hundred and nineteen obese patients (40 males; 79 females) underwent psychological evaluation and psychiatric interview, and a dietitian evaluated their eating habits...
November 10, 2016: Journal of Affective Disorders
https://www.readbyqxmd.com/read/27843483/human-rights-of-asylum-seekers-with-psychosocial-disabilities-in-europe
#16
Mauro Giovanni Carta, Maria Francesca Moro, Antonio Preti, Jutta Lindert, Dinesh Bhugra, Mattias Angermeyer, Marcello Vellante
BACKGROUND: The migrants crossing the Mediterranean towards Europe have dramatically been increased in 2015 as the number of incidents and deaths. OBJECTIVE: This editorial summarizes the results of our work and highlights some critical aspects that hinder the care to asylum seekers with stress disorders. METHOD: Screening for mental disorders was performed in all migrants joint three camps in Sardinia (January-September 2015) using K6, Short Screening Scale for Post Traumatic Stress Disorder (PTSD) and with an interview...
2016: Clinical Practice and Epidemiology in Mental Health: CP & EMH
https://www.readbyqxmd.com/read/27837521/bipolar-disorder-in-children-and-adolescents-diagnostic-inpatient-rates-from-2000-to-2013-in-germany
#17
Pradeep Rao, Julie K Moore, Richard Stewart, Kevin Runions, Natasha Bear, Janice W Y Wong, Martin Holtmann, Florian D Zepf
BACKGROUND: Despite growing consensus on nosology and epidemiology of bipolar disorder (BD) in minors, differences remain. We contribute to this discussion by measuring long-term trends in the inpatient discharge rates of BD in minors. METHODS: Nationwide German inpatient discharge diagnoses of BD and other related psychiatric disorders were mapped between 2008 and 2013 using registry data from the German Federal Health Monitoring System. This was compared with previously published data, 2000-2007, to assess long-term trends in diagnosis of BD at discharge...
December 2016: International Journal of Bipolar Disorders
https://www.readbyqxmd.com/read/27835716/targeting-treatments-to-improve-cognitive-function-in-mood-disorder-suggestions-from-trials-using-erythropoietin
#18
Kamilla Woznica Miskowiak, A John Rush, Thomas A Gerds, Maj Vinberg, Lars V Kessing
OBJECTIVE: There is no established efficacious treatment for cognitive dysfunction in unipolar and bipolar disorder. This may be partially due to lack of consensus regarding the need to screen for cognitive impairment in cognition trials or which screening criteria to use. We have demonstrated in 2 randomized placebo-controlled trials that 8 weeks of erythropoietin (EPO) treatment has beneficial effects on verbal memory across unipolar and bipolar disorder, with 58% of EPO-treated patients displaying a clinically relevant memory improvement as compared to 15% of those treated with placebo...
November 8, 2016: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/27834153/childhood-trauma-is-associated-with-increased-brain-responses-to-emotionally-negative-as-compared-with-positive-faces-in-patients-with-psychotic-disorders
#19
M Aas, K Kauppi, C L Brandt, M Tesli, T Kaufmann, N E Steen, I Agartz, L T Westlye, O A Andreassen, I Melle
BACKGROUND: Childhood trauma increases risk of a range of mental disorders including psychosis. Whereas the mechanisms are unclear, previous evidence has implicated atypical processing of emotions among the core cognitive models, in particular suggesting altered attentional allocation towards negative stimuli and increased negativity bias. Here, we tested the association between childhood trauma and brain activation during emotional face processing in patients diagnosed with psychosis continuum disorders...
November 11, 2016: Psychological Medicine
https://www.readbyqxmd.com/read/27834101/outcome-of-first-episode-acute-and-transient-psychotic-disorder-in-hong-kong-chinese-a-20-year-retrospective-follow-up-study
#20
Johannes Yin Kwong Poon, Chi Ming Leung
BACKGROUND: 'Acute and transient psychotic disorder' (ATPD) is a category in ICD-10 marked by psychosis with acute onset and early remission. It remains relatively under-researched, despite controversies over its nosological status in the current classification system. AIMS: (1) To assess the changes in diagnosis over time in patients initially diagnosed as ATPD. (2) To identify factors predicting changes in diagnosis, and compare the long-term outcomes of various patterns of diagnostic shift...
November 11, 2016: Nordic Journal of Psychiatry
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