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https://www.readbyqxmd.com/read/29352727/re-evaluation-of-target-lipid-model-derived-hc5-predictions-for-hydrocarbons
#1
Joy A McGrath, Christopher J Fanelli, Dominic M Di Toro, Thomas F Parkerton, Aaron D Redman, Miriam Leon Paumen, Mike Comber, Charles V Eadsforth, Klaas den Haan
The Target Lipid Model (TLM) has been previously applied to predict the aquatic toxicity of hydrocarbons and other non-ionic organic chemicals and for deriving HC5 values, concentrations above which 95% of species should be protected. Several concerns were identified with the TLM-derived HC5 when applied in a substance risk assessment context. These shortcomings were addressed by expanding the acute and chronic toxicity databases to include more diverse taxonomic groups and increase the number of species. The TLM was recalibrated with these expanded databases resulting in critical target lipid body burdens and acute-to-chronic ratios that met the required guidelines for using species sensitivity distributions in substance risk assessment...
January 20, 2018: Environmental Toxicology and Chemistry
https://www.readbyqxmd.com/read/29352463/temperature-dependency-of-intraguild-predation-between-native-and-invasive-crabs
#2
Tanya L Rogers, Tarik C Gouhier, David L Kimbro
Environmental factors such as temperature can affect the geographical distribution of species directly by exceeding physiological tolerances, or indirectly by altering physiological rates that dictate the sign and strength of species interactions. Although the direct effects of environmental conditions are relatively well studied, the effects of environmentally-mediated species interactions have garnered less attention. In this study, we examined the temperature-dependency of size-structured intraguild predation (IGP) between native blue crabs (Callinectes sapidus, the IG predator) and invasive green crabs (Carcinus maenas, the IG prey) to evaluate how the effect of temperature on competitive and predatory rates may influence the latitudinal distribution of these species...
January 20, 2018: Ecology
https://www.readbyqxmd.com/read/29351762/inclusion-of-edaphic-predictors-for-enhancement-of-models-to-determine-distribution-of-soil-transmitted-helminths-the-case-of-zimbabwe
#3
Nicholas Midzi, Blessing Kavhu, Portia Manangazira, Isaac Phiri, Susan L Mutambu, Cremants Tshuma, Moses J Chimbari, Shungu Munyati, Stanely M Midzi, Lincon Charimari, Anatoria Ncube, Masceline J Mutsaka-Makuvaza, White Soko, Emmanuel Madzima, Gibson Hlerema, Joel Mbedzi, Gibson Mhlanga, Mhosisi Masocha
BACKGROUND: Reliable mapping of soil-transmitted helminth (STH) parasites requires rigorous statistical and machine learning algorithms capable of integrating the combined influence of several determinants to predict distributions. This study tested whether combining edaphic predictors with relevant environmental predictors improves model performance when predicting the distribution of STH, Ascaris lumbricoides and hookworms at a national scale in Zimbabwe. METHODS: Geo-referenced parasitological data obtained from a 2010/2011 national survey indicating a confirmed presence or absence of STH among school children aged 10-15 years was used to calibrate ten species distribution models (SDMs)...
January 19, 2018: Parasites & Vectors
https://www.readbyqxmd.com/read/29348468/the-potential-impact-of-invasive-woody-oil-plants-on-protected-areas-in-china-under-future-climate-conditions
#4
Guanghui Dai, Jun Yang, Siran Lu, Conghong Huang, Jing Jin, Peng Jiang, Pengbo Yan
Biodiesel produced from woody oil plants is considered a green substitute for fossil fuels. However, a potential negative impact of growing woody oil plants on a large scale is the introduction of highly invasive species into susceptible regions. In this study, we examined the potential invasion risk of woody oil plants in China's protected areas under future climate conditions. We simulated the current and future potential distributions of three invasive woody oil plants, Jatropha curcas, Ricinus communis, and Aleurites moluccana, under two climate change scenarios (RCP2...
January 18, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29347089/alternative-steady-states-in-ecological-networks
#5
Yael Fried, Nadav M Shnerb, David A Kessler
In many natural situations, one observes a local system with many competing species that is coupled by weak immigration to a regional species pool. The dynamics of such a system is dominated by its stable and uninvadable (SU) states. When the competition matrix is random, the number of SUs depends on the average value and variance of its entries. Here we consider the problem in the limit of weak competition and large variance. Using a yes-no interaction model, we show that the number of SUs corresponds to the number of maximum cliques in an Erdös-Rényi network...
July 2017: Physical Review. E
https://www.readbyqxmd.com/read/29346992/existence-and-construction-of-large-stable-food-webs
#6
Jan O Haerter, Namiko Mitarai, Kim Sneppen
Ecological diversity is ubiquitous despite the restrictions imposed by competitive exclusion and apparent competition. To explain the observed richness of species in a given habitat, food-web theory has explored nonlinear functional responses, self-interaction, or spatial structure and dispersal-model ingredients that have proven to promote stability and diversity. We return instead here to classical Lotka-Volterra equations, where species-species interaction is characterized by a simple product and spatial restrictions are ignored...
September 2017: Physical Review. E
https://www.readbyqxmd.com/read/29346563/lc3-immunostaining-in-the-inferior-olivary-nuclei-of-cats-with-niemann-pick-disease-type-c1-is-associated-with-patterned-purkinje-cell-loss
#7
Brittney L Gurda, Jessica H Bagel, Samantha J Fisher, Mark L Schultz, Andrew P Lieberman, Peter Hand, Charles H Vite, Gary P Swain
The feline model of Niemann-Pick disease, type C1 (NPC1) recapitulates the clinical, neuropathological, and biochemical abnormalities present in children with NPC1. The hallmarks of disease are the lysosomal storage of unesterified cholesterol and multiple sphingolipids in neurons, and the spatial and temporal distribution of Purkinje cell death. In feline NPC1 brain, microtubule-associated protein 1 light chain 3 (LC3) accumulations, indicating autophagosomes, were found within axons and presynaptic terminals...
January 13, 2018: Journal of Neuropathology and Experimental Neurology
https://www.readbyqxmd.com/read/29346521/the-intracellular-and-intercellular-cross-talk-during-subsidiary-cell-formation-in-zea-mays-existing-and-novel-components-orchestrating-cell-polarization-and-asymmetric-division
#8
P Apostolakos, P Livanos, E Giannoutsou, E Panteris, B Galatis
Background: Formation of stomatal complexes in Poaceae is the outcome of three asymmetric and one symmetric cell division occurring in particular leaf protodermal cells. In this definite sequence of cell division events, the generation of subsidiary cells is of particular importance and constitutes an attractive model for studying local intercellular stimulation. In brief, an induction stimulus emitted by the guard cell mother cells (GMCs) triggers a series of polarization events in their laterally adjacent protodermal cells...
January 15, 2018: Annals of Botany
https://www.readbyqxmd.com/read/29344733/linking-intraspecific-trait-variability-and-spatial-patterns-of-subtropical-trees
#9
En-Rong Yan, Liu-Li Zhou, Han Y H Chen, Xi-Hua Wang, Xiang-Yu Liu
The importance of intraspecific trait variability (ITV) to the spatial distribution of individual species is unclear. We hypothesized that intraspecific trait dispersions underlying niche processes deviate more from null model expectations, by reducing their spread (range and variance), kurtosis, and standard deviation of near-neighbor distance, for species with aggregated than those with random distributions. The link between species' spatial distributions and ITV patterns was examined using an individual tree-based trait data set, in which specific leaf area, mean leaf area, leaf dry matter content, and diameter at breast height were measured for 18,773 stems of 45 species in a 4...
January 17, 2018: Oecologia
https://www.readbyqxmd.com/read/29343741/species-distribution-modelling-contrasting-presence-only-models-with-plot-abundance-data
#10
Vitor H F Gomes, Stéphanie D IJff, Niels Raes, Iêda Leão Amaral, Rafael P Salomão, Luiz de Souza Coelho, Francisca Dionízia de Almeida Matos, Carolina V Castilho, Diogenes de Andrade Lima Filho, Dairon Cárdenas López, Juan Ernesto Guevara, William E Magnusson, Oliver L Phillips, Florian Wittmann, Marcelo de Jesus Veiga Carim, Maria Pires Martins, Mariana Victória Irume, Daniel Sabatier, Jean-François Molino, Olaf S Bánki, José Renan da Silva Guimarães, Nigel C A Pitman, Maria Teresa Fernandez Piedade, Abel Monteagudo Mendoza, Bruno Garcia Luize, Eduardo Martins Venticinque, Evlyn Márcia Moraes de Leão Novo, Percy Núñez Vargas, Thiago Sanna Freire Silva, Angelo Gilberto Manzatto, John Terborgh, Neidiane Farias Costa Reis, Juan Carlos Montero, Katia Regina Casula, Beatriz S Marimon, Ben-Hur Marimon, Euridice N Honorio Coronado, Ted R Feldpausch, Alvaro Duque, Charles Eugene Zartman, Nicolás Castaño Arboleda, Timothy J Killeen, Bonifacio Mostacedo, Rodolfo Vasquez, Jochen Schöngart, Rafael L Assis, Marcelo Brilhante Medeiros, Marcelo Fragomeni Simon, Ana Andrade, William F Laurance, José Luís Camargo, Layon O Demarchi, Susan G W Laurance, Emanuelle de Sousa Farias, Henrique Eduardo Mendonça Nascimento, Juan David Cardenas Revilla, Adriano Quaresma, Flavia R C Costa, Ima Célia Guimarães Vieira, Bruno Barçante Ladvocat Cintra, Hernán Castellanos, Roel Brienen, Pablo R Stevenson, Yuri Feitosa, Joost F Duivenvoorden, Gerardo A Aymard C, Hugo F Mogollón, Natalia Targhetta, James A Comiskey, Alberto Vicentini, Aline Lopes, Gabriel Damasco, Nállarett Dávila, Roosevelt García-Villacorta, Carolina Levis, Juliana Schietti, Priscila Souza, Thaise Emilio, Alfonso Alonso, David Neill, Francisco Dallmeier, Leandro Valle Ferreira, Alejandro Araujo-Murakami, Daniel Praia, Dário Dantas do Amaral, Fernanda Antunes Carvalho, Fernanda Coelho de Souza, Kenneth Feeley, Luzmila Arroyo, Marcelo Petratti Pansonato, Rogerio Gribel, Boris Villa, Juan Carlos Licona, Paul V A Fine, Carlos Cerón, Chris Baraloto, Eliana M Jimenez, Juliana Stropp, Julien Engel, Marcos Silveira, Maria Cristina Peñuela Mora, Pascal Petronelli, Paul Maas, Raquel Thomas-Caesar, Terry W Henkel, Doug Daly, Marcos Ríos Paredes, Tim R Baker, Alfredo Fuentes, Carlos A Peres, Jerome Chave, Jose Luis Marcelo Pena, Kyle G Dexter, Miles R Silman, Peter Møller Jørgensen, Toby Pennington, Anthony Di Fiore, Fernando Cornejo Valverde, Juan Fernando Phillips, Gonzalo Rivas-Torres, Patricio von Hildebrand, Tinde R van Andel, Ademir R Ruschel, Adriana Prieto, Agustín Rudas, Bruce Hoffman, César I A Vela, Edelcilio Marques Barbosa, Egleé L Zent, George Pepe Gallardo Gonzales, Hilda Paulette Dávila Doza, Ires Paula de Andrade Miranda, Jean-Louis Guillaumet, Linder Felipe Mozombite Pinto, Luiz Carlos de Matos Bonates, Natalino Silva, Ricardo Zárate Gómez, Stanford Zent, Therany Gonzales, Vincent A Vos, Yadvinder Malhi, Alexandre A Oliveira, Angela Cano, Bianca Weiss Albuquerque, Corine Vriesendorp, Diego Felipe Correa, Emilio Vilanova Torre, Geertje van der Heijden, Hirma Ramirez-Angulo, José Ferreira Ramos, Kenneth R Young, Maira Rocha, Marcelo Trindade Nascimento, Maria Natalia Umaña Medina, Milton Tirado, Ophelia Wang, Rodrigo Sierra, Armando Torres-Lezama, Casimiro Mendoza, Cid Ferreira, Cláudia Baider, Daniel Villarroel, Henrik Balslev, Italo Mesones, Ligia Estela Urrego Giraldo, Luisa Fernanda Casas, Manuel Augusto Ahuite Reategui, Reynaldo Linares-Palomino, Roderick Zagt, Sasha Cárdenas, William Farfan-Rios, Adeilza Felipe Sampaio, Daniela Pauletto, Elvis H Valderrama Sandoval, Freddy Ramirez Arevalo, Isau Huamantupa-Chuquimaco, Karina Garcia-Cabrera, Lionel Hernandez, Luis Valenzuela Gamarra, Miguel N Alexiades, Susamar Pansini, Walter Palacios Cuenca, William Milliken, Joana Ricardo, Gabriela Lopez-Gonzalez, Edwin Pos, Hans Ter Steege
Species distribution models (SDMs) are widely used in ecology and conservation. Presence-only SDMs such as MaxEnt frequently use natural history collections (NHCs) as occurrence data, given their huge numbers and accessibility. NHCs are often spatially biased which may generate inaccuracies in SDMs. Here, we test how the distribution of NHCs and MaxEnt predictions relates to a spatial abundance model, based on a large plot dataset for Amazonian tree species, using inverse distance weighting (IDW). We also propose a new pipeline to deal with inconsistencies in NHCs and to limit the area of occupancy of the species...
January 17, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29343597/evidence-for-dispersal-syndromes-in-freshwater-fishes
#11
Lise Comte, Julian D Olden
Dispersal is a fundamental process defining the distribution of organisms and has long been a topic of inquiry in ecology and evolution. Emerging research points to an interdependency of dispersal with a diverse suite of traits in terrestrial organisms, however the extent to which such dispersal syndromes exist in freshwater species remains uncertain. Here, we test whether dispersal in freshwater fishes (1) is a fixed property of species, and (2) correlates with life-history, morphological, ecological and behavioural traits, using a global dataset of dispersal distances collected from the literature encompassing 116 riverine species and 196 locations...
January 31, 2018: Proceedings. Biological Sciences
https://www.readbyqxmd.com/read/29343494/uncovering-genomic-regions-associated-with-trypanosoma-infections-in-wild-populations-of-the-tsetse-fly-glossina-fuscipes
#12
Andrea Gloria-Soria, W Augustine Dunn, Xiaoqing Yu, Aurélien Vigneron, Kuang-Yao Lee, Mo Li, Brian L Weiss, Hongyu Zhao, Serap Aksoy, Adalgisa Caccone
Vector-borne diseases are responsible for more than one million deaths every year but genomic resources for most species responsible for their transmission are limited. This is true for neglected diseases such as sleeping sickness (Human African Trypanosomiasis), a disease caused by Trypanosoma parasites vectored by several species of tseste flies within the genus Glossina We describe an integrative approach that identifies statistical associations between trypanosome infection status of Glossina fuscipes fuscipes (Gff) flies from Uganda, for which functional studies are complicated because the species cannot be easily maintained in laboratory colonies, and ~73,000 polymorphic sites distributed across the genome...
January 17, 2018: G3: Genes—Genomes—Genetics
https://www.readbyqxmd.com/read/29343279/spatial-distribution-and-habitat-characterization-of-mosquito-species-during-the-dry-season-along-the-mara-river-and-its-tributaries-in-kenya-and-tanzania
#13
Gabriel O Dida, Douglas N Anyona, Paul O Abuom, Daniel Akoko, Samson O Adoka, Ally-Said Matano, Philip O Owuor, Collins Ouma
BACKGROUND: Vector-borne diseases are increasingly becoming a major health problem among communities living along the major rivers of Africa. Although larger water bodies such as lakes and dams have been extensively researched, rivers and their tributaries have largely been ignored. This study sought to establish the spatial distribution of mosquito species during the dry season and further characterize their habitats along the Mara River and its tributaries. METHODS: In this cross-sectional survey, mosquito larvae were sampled along the Mara River, its two perennial tributaries (Amala and Nyangores), drying streams, and adjacent aquatic habitats (e...
January 18, 2018: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/29341358/thermal-and-hydrologic-responses-to-climate-change-predict-marked-alterations-in-boreal-stream-invertebrate-assemblages
#14
Kaisa-Riikka Mustonen, Heikki Mykrä, Hannu Marttila, Romain Sarremejane, Noora Veijalainen, Kalle Sippel, Timo Muotka, Charles P Hawkins
Air temperature at the northernmost latitudes is predicted to increase steeply and precipitation to become more variable by the end of the 21st century, resulting in altered thermal and hydrological regimes. We applied five climate scenarios to predict the future (2070 to 2100) benthic macroinvertebrate assemblages at 239 near-pristine sites across Finland (ca. 1200 km latitudinal span). We used a multitaxon distribution model with air temperature and modeled daily flow as predictors. As expected, projected air temperature increased the most in northernmost Finland...
January 17, 2018: Global Change Biology
https://www.readbyqxmd.com/read/29340234/achilles-heel-of-a-powerful-invader-restrictions-on-distribution-and-disappearance-of-feral-pigs-from-a-protected-area-in-northern-pantanal-western-brazil
#15
Jose L P Cordeiro, Gabriel S Hofmann, Carlos Fonseca, Luiz Flamarion B Oliveira
This paper focuses on a rare case of natural disappearance of feral pigs (Sus scrofa) in an extensive area without using traditional methods of eradication programs. The study was conducted both in the Private Reserve of Natural Heritage (PRNH) Sesc Pantanal and in an adjacent traditional private cattle ranch. In 1998, feral pigs were abundant and widely distributed in the PRNH. However, the feral pigs gradually disappeared from the area and currently, the absence of pigs in the PRNH contrasts with the adjacent cattle ranch where the species is abundant...
2018: PeerJ
https://www.readbyqxmd.com/read/29339971/terzyme-a-tool-for-identification-and-analysis-of-the-plant-terpenome
#16
Piyush Priya, Archana Yadav, Jyoti Chand, Gitanjali Yadav
Background: Terpenoid hydrocarbons represent the largest and most ancient group of phytochemicals, such that the entire chemical library of a plant is often referred to as its 'terpenome'. Besides having numerous pharmacological properties, terpenes contribute to the scent of the rose, the flavors of cinnamon and the yellow of sunflowers. Rapidly increasing -omics datasets provide an unprecedented opportunity for terpenome detection, paving the way for automated web resources dedicated to phytochemical predictions in genomic data...
2018: Plant Methods
https://www.readbyqxmd.com/read/29338715/landscape-genomics-natural-selection-drives-the-evolution-of-mitogenome-in-penguins
#17
Barbara Ramos, Daniel González-Acuña, David E Loyola, Warren E Johnson, Patricia G Parker, Melanie Massaro, Gisele P M Dantas, Marcelo D Miranda, Juliana A Vianna
BACKGROUND: Mitochondria play a key role in the balance of energy and heat production, and therefore the mitochondrial genome is under natural selection by environmental temperature and food availability, since starvation can generate more efficient coupling of energy production. However, selection over mitochondrial DNA (mtDNA) genes has usually been evaluated at the population level. We sequenced by NGS 12 mitogenomes and with four published genomes, assessed genetic variation in ten penguin species distributed from the equator to Antarctica...
January 16, 2018: BMC Genomics
https://www.readbyqxmd.com/read/29337578/physiologically-based-pharmacokinetic-modeling-in-lead-optimization-i-evaluation-and-adaptation-of-gastroplus-to-predict-bioavailability-of-medchem-series
#18
Pankaj R Daga, Michael B Bolger, Ian S Haworth, Robert Daniel Clark, Eric J Martin
When medicinal chemists need to improve bioavailability (%F) within a chemical series during lead optimization, they synthesize new series members with systematically modified properties mainly by following experience and general rules of thumb. More quantitative models that predict %F of proposed compounds from chemical structure alone have proven elusive. Global empirical %F quantitative structure-property (QSPR) models perform poorly and projects have too little data to train local %F QSPR models. Mechanistic oral absorption and physiologically-based pharmacokinetic (PBPK) models simulate the dissolution, absorption, systemic distribution, and clearance of a drug in preclinical species and humans...
January 16, 2018: Molecular Pharmaceutics
https://www.readbyqxmd.com/read/29337282/comparative-proteome-analysis-of-monolayer-and-spheroid-culture-of-canine-osteosarcoma-cells
#19
Christiane Gebhard, Ingrid Miller, Karin Hummel, Martina Neschi Née Ondrovics, Sarah Schlosser, Ingrid Walter
Osteosarcoma is an aggressive bone tumor with high metastasis rate in the lungs and affects both humans and dogs in a similar way. Three-dimensional tumor cell cultures mimic the in vivo situation of micro-tumors and metastases and are therefore better experimental in vitro models than the often applied two-dimensional monolayer cultures. The aim of the present study was to perform comparative proteomics of standard monolayer cultures of canine osteosarcoma cells (D17) and three-dimensional spheroid cultures, to better characterize the 3D model before starting with experiments like migration assays...
January 11, 2018: Journal of Proteomics
https://www.readbyqxmd.com/read/29337274/species-delimitation-of-the-north-american-orchard-spider-leucauge-venusta-walckenaer-1841-araneae-tetragnathidae
#20
Jesús A Ballesteros, Gustavo Hormiga
The orchard spider, Leucauge venusta (Walckenaer, 1841) is one of the most common and abundant orb-weavers in North America. This species has a broad geographic distribution extending across tropical and temperate regions of the Americas from Canada to Brazil. Guided by a preliminary observation of the barcode gap between sequences from specimens of L. venusta collected in Florida and other North American localities, we collected across a transect through southeastern states of the USA to investigate the observed genetic divide...
January 11, 2018: Molecular Phylogenetics and Evolution
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