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https://www.readbyqxmd.com/read/28087735/relationships-linking-emotional-motor-cognitive-and-gabaergic-dysfunctions-in-dystrophin-deficient-mdx-mice
#1
Cyrille Vaillend, Rémi Chaussenot
Alterations in the Duchenne muscular dystrophy (DMD) gene have been associated with enhanced stress reactivity in vertebrate species, suggesting a role for brain dystrophin in fear-related behavioral and cognitive processes. Because the loss of dystrophin (Dp427) reduces clustering of central GABAA receptors, it is suspected that local inhibitory tuning and modulation of neuronal excitability are perturbed in a distributed brain circuit that normally controls such critical behavioral functions. In this study we undertook a large-scale behavioral study to evaluate fear-related behavioral disturbances in dystrophin-deficient mdx mice...
January 13, 2017: Human Molecular Genetics
https://www.readbyqxmd.com/read/28086897/application-of-the-analytic-hierarchy-approach-to-the-risk-assessment-of-zika-virus-disease-transmission-in-guangdong-province-china
#2
Xing Li, Tao Liu, Lifeng Lin, Tie Song, Xiaolong Du, Hualiang Lin, Jianpeng Xiao, Jianfeng He, Liping Liu, Guanghu Zhu, Weilin Zeng, Lingchuan Guo, Zheng Cao, Wenjun Ma, Yonghui Zhang
BACKGROUND: An international spread of Zika virus (ZIKV) infection has attracted global attention in 2015. The infection also affected Guangdong province, which is located in southern China. Multiple factors, including frequent communication with South America and Southeast Asia, suitable climate (sub-tropical) for the habitat of Aedes species, may increase the risk of ZIKV disease transmission in this region. METHODS: An analytic hierarchy process (AHP) method was used to develop a semi-quantitative ZIKV risk assessment model...
January 13, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28086791/identification-of-functional-enolase-genes-of-the-silkworm-bombyx-mori-from-public-databases-with-a-combination-of-dry-and-wet-bench-processes
#3
Akira Kikuchi, Takeru Nakazato, Katsuhiko Ito, Yosui Nojima, Takeshi Yokoyama, Kikuo Iwabuchi, Hidemasa Bono, Atsushi Toyoda, Asao Fujiyama, Ryoichi Sato, Hiroko Tabunoki
BACKGROUND: Various insect species have been added to genomic databases over the years. Thus, researchers can easily obtain online genomic information on invertebrates and insects. However, many incorrectly annotated genes are included in these databases, which can prevent the correct interpretation of subsequent functional analyses. To address this problem, we used a combination of dry and wet bench processes to select functional genes from public databases. RESULTS: Enolase is an important glycolytic enzyme in all organisms...
January 13, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28077766/historical-citizen-science-to-understand-and-predict-climate-driven-trout-decline
#4
Miguel Clavero, Miquel Ninyerola, Virgilio Hermoso, Ana Filipa Filipe, Magda Pla, Daniel Villero, Lluís Brotons, Miguel Delibes
Historical species records offer an excellent opportunity to test the predictive ability of range forecasts under climate change, but researchers often consider that historical records are scarce and unreliable, besides the datasets collected by renowned naturalists. Here, we demonstrate the relevance of biodiversity records developed through citizen-science initiatives generated outside the natural sciences academia. We used a Spanish geographical dictionary from the mid-nineteenth century to compile over 10 000 freshwater fish records, including almost 4 000 brown trout (Salmo trutta) citations, and constructed a historical presence-absence dataset covering over 2 000 10 × 10 km cells, which is comparable to present-day data...
January 11, 2017: Proceedings. Biological Sciences
https://www.readbyqxmd.com/read/28077180/understanding-transmissibility-patterns-of-chagas-disease-through-complex-vector-host-networks
#5
Laura Rengifo-Correa, Christopher R Stephens, Juan J Morrone, Juan Luis Téllez-Rendón, Constantino González-Salazar
Chagas disease is one of the most important vector-borne zoonotic diseases in Latin America. Control strategies could be improved if transmissibility patterns of its aetiologic agent, Trypanosoma cruzi, were better understood. To understand transmissibility patterns of Chagas disease in Mexico, we inferred potential vectors and hosts of T. cruzi from geographic distributions of nine species of Triatominae and 396 wild mammal species, respectively. The most probable vectors and hosts of T. cruzi were represented in a Complex Inference Network, from which we formulated a predictive model and several associated hypotheses about the ecological epidemiology of Chagas disease...
January 12, 2017: Parasitology
https://www.readbyqxmd.com/read/28077090/gbs-based-single-dosage-markers-for-linkage-and-qtl-mapping-allow-gene-mining-for-yield-related-traits-in-sugarcane
#6
Thiago Willian Almeida Balsalobre, Guilherme da Silva Pereira, Gabriel Rodrigues Alves Margarido, Rodrigo Gazaffi, Fernanda Zatti Barreto, Carina Oliveira Anoni, Cláudio Benício Cardoso-Silva, Estela Araújo Costa, Melina Cristina Mancini, Hermann Paulo Hoffmann, Anete Pereira de Souza, Antonio Augusto Franco Garcia, Monalisa Sampaio Carneiro
BACKGROUND: Sugarcane (Saccharum spp.) is predominantly an autopolyploid plant with a variable ploidy level, frequent aneuploidy and a large genome that hampers investigation of its organization. Genetic architecture studies are important for identifying genomic regions associated with traits of interest. However, due to the genetic complexity of sugarcane, the practical applications of genomic tools have been notably delayed in this crop, in contrast to other crops that have already advanced to marker-assisted selection (MAS) and genomic selection...
January 11, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28073565/heterogeneous-distribution-in-sediments-and-dispersal-in-waters-of-alexandrium-minutum-in-a-semi-enclosed-coastal-ecosystem
#7
Z K Klouch, F Caradec, M Plus, T Hernández-Fariñas, L Pineau-Guillou, A Chapelle, S Schmitt, J Quéré, L Guillou, R Siano
Within the framework of research aimed at using genetic methods to evaluate harmful species distribution and their impact on coastal ecosystems, a portion of the ITS1rDNA of Alexandrium minutum was amplified by real-time PCR from DNA extracts of superficial (1-3cm) sediments of 30 subtidal and intertidal stations of the Bay of Brest (Brittany, France), during the winters of 2013 and 2015. Cell germinations and rDNA amplifications of A. minutum were obtained for sediments of all sampled stations, demonstrating that the whole bay is currently contaminated by this toxic species...
December 2016: Harmful Algae
https://www.readbyqxmd.com/read/28073553/the-effects-of-light-intensity-on-the-growth-of-japanese-gambierdiscus-spp-dinophyceae
#8
Takamichi Yoshimatsu, Chaoyu Tie, Haruo Yamaguchi, Hiroshi Funaki, Chiho Honma, Kouki Tanaka, Masao Adachi
Marine toxic dinoflagellates of the genus Gambierdiscus are the causative agents of ciguatera fish poisoning (CFP), a form of seafood poisoning that is widespread in tropical, subtropical and temperate regions worldwide. The distributions of Gambierdiscus australes, Gambierdiscus scabrosus and two phylotypes of Gambierdiscus spp. type 2 and type 3 have been reported for the waters surrounding the main island of Japan. To explore the bloom dynamics and the vertical distribution of these Japanese species and phylotypes of Gambierdiscus, the effects of light intensity on their growth were tested, using a photoirradiation-culture system...
December 2016: Harmful Algae
https://www.readbyqxmd.com/read/28073442/toward-predicting-dinophysis-blooms-off-nw-iberia-a-decade-of-events
#9
Ma Teresa Moita, Yolanda Pazos, Carlos Rocha, Rita Nolasco, Paulo B Oliveira
Dinophysis acuminata and Dinophysis acuta are recurrent species off NW Iberia but their outbreaks occur under different conditions. A decade (2004-2013) of weekly data for each species at two sentinel stations located at the entrance of Rias de Aveiro-AV (NW Portugal, 40°38.6'N) and Pontevedra-PO (Galicia, Spain, 42°21.5'N), were used to investigate the regional synchronism and mesoscale differences related to species detection, bloom (>200cellsL(-1)) initiation and development. Results highlight the high interannual variability of bloom events and summarize the associated meteorological/oceanographic conditions...
March 2016: Harmful Algae
https://www.readbyqxmd.com/read/28073440/climate-variability-and-dinophysis-acuta-blooms-in-an-upwelling-system
#10
Patricio A Díaz, Manuel Ruiz-Villarreal, Yolanda Pazos, Teresa Moita, Beatriz Reguera
Dinophysis acuta is a frequent seasonal lipophilic toxin producer in European Atlantic coastal waters associated with thermal stratification. In the Galician Rías, populations of D. acuta with their epicentre located off Aveiro (northern Portugal), typically co-occur with and follow those of Dinophysis acuminata during the upwelling transition (early autumn) as a result of longshore transport. During hotter than average summers, D. acuta blooms also occur in August in the Rías, when they replace D. acuminata...
March 2016: Harmful Algae
https://www.readbyqxmd.com/read/28073438/individual-based-modelling-of-the-development-and-transport-of-a-karenia-mikimotoi-bloom-on-the-north-west-european-continental-shelf
#11
P A Gillibrand, B Siemering, P I Miller, K Davidson
In 2006, a large and prolonged bloom of the dinoflagellate Karenia mikimotoi occurred in Scottish coastal waters, causing extensive mortalities of benthic organisms including annelids and molluscs and some species of fish (Davidson et al., 2009). A coupled hydrodynamic-algal transport model was developed to track the progression of the bloom around the Scottish coast during June-September 2006 and hence investigate the processes controlling the bloom dynamics. Within this individual-based model, cells were capable of growth, mortality and phototaxis and were transported by physical processes of advection and turbulent diffusion, using current velocities extracted from operational simulations of the MRCS ocean circulation model of the North-west European continental shelf...
March 2016: Harmful Algae
https://www.readbyqxmd.com/read/28072530/the-effect-of-%C3%AE-cyclodextrin-on-the-multistate-species-distribution-of-3-methoxy-4-7-dihydroxyflavylium-discrimination-of-the-two-hemiketal-enantiomers
#12
Sandra Gago, Nuno Basílio, Alexandre Quintas, Fernando Pina
The effect of the β-cyclodextrin on the mole fraction distribution of the multistate species of the anthocyanins model compound, 3-methoxy-4',7-dihydroxyflavylium, was studied by NMR, stopped flow, circular dichroism and UV-Visible absorption spectroscopy. The formation of inclusion complexes with hemiketal and trans-chalcone, possessing transition dipole moments in a parallel orientation to the cyclodextrin n-fold axis, was unequivocally proved by means of the positive induced circular dichroism signal. The discrimination of the two hemiketal enantiomers was achieved by the splitting of 1H NMR peaks in the presence β-cyclodextrin...
January 10, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28071788/chromosome-inversions-and-ecological-plasticity-in-the-main-african-malaria-mosquitoes
#13
Diego Ayala, Pelayo Acevedo, Marco Pombi, Ibrahima Dia, Daniela Boccolini, Carlo Costantini, Frédéric Simard, Didier Fontenille
Chromosome inversions have fascinated the scientific community, mainly because of their role in the rapid adaption of different taxa to changing environments. However, the ecological traits linked to chromosome inversions have been poorly studied. Here, we investigated the roles played by 23 chromosome inversions in the adaptation of the four major African malaria mosquitoes to local environments in Africa. We studied their distribution patterns by using spatially explicit modeling and characterized the ecogeographical determinants of each inversion range...
January 10, 2017: Evolution; International Journal of Organic Evolution
https://www.readbyqxmd.com/read/28070978/testing-for-local-adaptation-and-evolutionary-potential-along-altitudinal-gradients-in-rainforest-drosophila-beyond-laboratory-estimates
#14
Eleanor K O'Brien, Megan Higgie, Alan Reynolds, Ary A Hoffmann, Jon R Bridle
Predicting how species will respond to the rapid climatic changes predicted this century is an urgent task. Species distribution models (SDMs) use the current relationship between environmental variation and species' abundances to predict the effect of future environmental change on their distributions. However, two common assumptions of SDMs are likely to be violated in many cases: (i) that the relationship of environment with abundance or fitness is constant throughout a species' range and will remain so in future and (ii) that abiotic factors (e...
January 10, 2017: Global Change Biology
https://www.readbyqxmd.com/read/28070303/using-species-distribution-models-to-define-nesting-habitat-of-the-eastern-metapopulation-of-double-crested-cormorants
#15
Kate L Sheehan, Samuel T Esswein, Brian S Dorr, Greg K Yarrow, Ron J Johnson
When organisms with similar phenotypes have conflicting management and conservation initiatives, approaches are needed to differentiate among subpopulations or discrete groups. For example, the eastern metapopulation of the double-crested cormorant (Phalacrocorax auritus) has a migratory phenotype that is culled because they are viewed as a threat to commercial and natural resources, whereas resident birds are targeted for conservation. Understanding the distinct breeding habitats of resident versus migratory cormorants would aid in identification and management decisions...
January 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/28070299/evaluating-citizen-science-data-for-forecasting-species-responses-to-national-forest-management
#16
Louise Mair, Philip J Harrison, Mari Jönsson, Swantje Löbel, Jenni Nordén, Juha Siitonen, Tomas Lämås, Anders Lundström, Tord Snäll
The extensive spatial and temporal coverage of many citizen science datasets (CSD) makes them appealing for use in species distribution modeling and forecasting. However, a frequent limitation is the inability to validate results. Here, we aim to assess the reliability of CSD for forecasting species occurrence in response to national forest management projections (representing 160,366 km(2)) by comparison against forecasts from a model based on systematically collected colonization-extinction data. We fitted species distribution models using citizen science observations of an old-forest indicator fungus Phellinus ferrugineofuscus...
January 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/28070287/mountains-too-high-and-valleys-too-deep-drive-population-structuring-and-demographics-in-a-qinghai-tibetan-plateau-frog-nanorana-pleskei-dicroglossidae
#17
Weiwei Zhou, Jieqiong Jin, Jun Wu, Hongman Chen, Junxiao Yang, Robert W Murphy, Jing Che
Pleistocene glacial-interglacial climatic oscillations greatly shaped the current genetic structure of many species. However, geographic features may influence the impact of climatic cycling. Distinct geographic and environmental characters between northern and southern parts of the eastern Qinghai-Tibetan Plateau (EQTP) facilitate explorations into the impacts of geographic features on species. The northern parts of EQTP contain large areas of marsh, and the environment is rather homogeneous. In contrast, the southern EQTP harbors complex alpine valleys and a much more heterogeneous setting...
January 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/28070271/heterogeneous-microcommunities-and-ecosystem-multifunctionality-in-seminatural-grasslands-under-three-management-modes
#18
Jingpeng Li, Zhirong Zheng, Hongtao Xie, Nianxi Zhao, Yubao Gao
Increasing attention has been paid to the relationship between biodiversity and ecosystem functioning (BEF) because of the rapid increase in species loss. However, over the past 20 years, most BEF studies only focused on the effect of species diversity on one or a few ecosystem functions, and only a few studies focused on ecosystem multifunctionality (i.e., the simultaneous provision of several ecosystem functions). Grassland ecosystems have important economic, environmental, and esthetic value; thus, this study focused on the heterogeneous microcommunities in grasslands under three management modes...
January 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/28069533/myrteae-phylogeny-calibration-biogeography-and-diversification-patterns-increased-understanding-in-the-most-species-rich-tribe-of-myrtaceae
#19
Thais N C Vasconcelos, Carol E B Proença, Berhaman Ahmad, Daniel S Aguilar, Reinaldo Aguilar, Bruno S Amorim, Keron Campbell, Itayguara R Costa, Plauto S De-Carvalho, Jair E Q Faria, Augusto Giaretta, Pepijn W Kooij, Duane F Lima, Fiorella F Mazine, Brigido Peguero, Gerhard Prenner, Matheus F Santos, Julia Soewarto, Astrid Wingler, Eve J Lucas
Myrteae (c. 2500 species; 51 genera) is the largest tribe of Myrtaceae and an ecologically important groups of angiosperms in the Neotropics. Systematic relationships in Myrteae are complex, hindering conservation initiatives and jeopardizing evolutionary modelling. A well-supported and robust phylogenetic hypothesis was here targeted towards a comprehensive understanding of the relationships within the tribe. The resultant topology was used as a base for key evolutionary analyses such as age estimation, historical biogeography and diversification rate patterns...
January 6, 2017: Molecular Phylogenetics and Evolution
https://www.readbyqxmd.com/read/28068923/domestication-of-rice-has-reduced-the-occurrence-of-transposable-elements-within-gene-coding-regions
#20
Xukai Li, Kai Guo, Xiaobo Zhu, Peng Chen, Ying Li, Guosheng Xie, Lingqiang Wang, Yanting Wang, Staffan Persson, Liangcai Peng
BACKGROUND: Transposable elements (TEs) are prominent features in many plant genomes, and patterns of TEs in closely related rice species are thus proposed as an ideal model to study TEs roles in the context of plant genome evolution. As TEs may contribute to improved rice growth and grain quality, it is of pivotal significance for worldwide food security and biomass production. RESULTS: We analyzed three cultivated rice species and their closest five wild relatives for distribution and content of TEs in their genomes...
January 9, 2017: BMC Genomics
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