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https://www.readbyqxmd.com/read/28241715/-a-prospective-randomized-control-trial-of-arthroscopic-surgery-for-stable-ramp-lesion-of-the-medial-meniscus
#1
X Liu, H Feng, L Hong, H Zhang
Objective: To evaluate the necessity of arthroscopic suture repair for the stable ramp lesion. Methods: From August 2008 to April 2012, 91 patients of consecutive cases were diagnosed as anterior cruciate ligament (ACL) injury associated with stable ramp lesion in Department of Sports Medicine Service of Beijing Jishuitan Hospital. All of the diagnosis was confirmed during arthroscopic surgeries. The patients were randomized into suture repair group and control group. The ACL was reconstructed using auto grafts of hamstring...
March 1, 2017: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
https://www.readbyqxmd.com/read/28241123/upper-urinary-tract-tumors-which-diagnostic-methods-are-needed
#2
Matthias Maruschke, Wolfgang Kram, Annette Zimpfer, Günther Kundt, Oliver W Hakenberg
OBJECTIVES: We reviewed the data of patients with upper urinary tract (UUT) tumors to evaluate the effectiveness of diagnostic procedures. METHODS: This retrospective study evaluated tumor characteristics, imaging procedures, epidemiological and follow-up data of 113 patients. We analyzed the importance of non-invasive and endoscopic diagnosis in addition to imaging as well as the influence of stage and grade on recurrence rate. RESULTS: Most tumors were urothelial carcinomas (92...
February 28, 2017: Urologia Internationalis
https://www.readbyqxmd.com/read/28241107/technical-note-development-of-a-cranial-phantom-for-assessing-perfusion-diffusion-and-biomechanics
#3
Naoki Ohno, Tosiaki Miyati, Tomohiro Chigusa, Hikari Usui, Shota Ishida, Yuki Hiramatsu, Satoshi Kobayashi, Toshifumi Gabata, Noam Alperin
PURPOSE: A novel cranial phantom was developed to simulate the relationships among factors such as blood perfusion, water diffusion, and biomechanics in intracranial tissue. METHODS: The cranial phantom consisted of a high-density polypropylene filter (mimicking brain parenchyma) with intra- and extra-filter spaces (mimicking cerebral artery and vein, respectively), and a capacitor space (mimicking the cerebrospinal fluid space). Pulsatile and steady flow with different flow rates were applied to the cranial phantom using a programmable pump...
February 27, 2017: Medical Physics
https://www.readbyqxmd.com/read/28241076/characterisation-of-liver-fat-in-the-uk-biobank-cohort
#4
Henry R Wilman, Matt Kelly, Steve Garratt, Paul M Matthews, Matteo Milanesi, Amy Herlihy, Micheal Gyngell, Stefan Neubauer, Jimmy D Bell, Rajarshi Banerjee, E Louise Thomas
Non-alcoholic fatty liver disease and the risk of progression to steatohepatitis, cirrhosis and hepatocellular carcinoma have been identified as major public health concerns. We have demonstrated the feasibility and potential value of measuring liver fat content by magnetic resonance imaging (MRI) in a large population in this study of 4,949 participants (aged 45-73 years) in the UK Biobank imaging enhancement. Despite requirements for only a single (≤3min) scan of each subject, liver fat was able to be measured as the MRI proton density fat fraction (PDFF) with an overall success rate of 96...
2017: PloS One
https://www.readbyqxmd.com/read/28241065/repeated-dexamphetamine-treatment-alters-the-dopaminergic-system-and-increases-the-phmri-response-to-methylphenidate
#5
Anouk Schrantee, Jordi L Tremoleda, Marzena Wylezinska-Arridge, Valentine Bouet, Peter Hesseling, Gideon F Meerhoff, Kora M de Bruin, Jan Koeleman, Thomas Freret, Michel Boulouard, Emilie Desfosses, Laurent Galineau, Alessandro Gozzi, François Dauphin, Willy Gsell, Jan Booij, Paul J Lucassen, Liesbeth Reneman
Dexamphetamine (AMPH) is a psychostimulant drug that is used both recreationally and as medication for attention deficit hyperactivity disorder. Preclinical studies have demonstrated that repeated exposure to AMPH can induce damage to nerve terminals of dopamine (DA) neurons. We here assessed the underlying neurobiological changes in the DA system following repeated AMPH exposure and pre-treated rats with AMPH or saline (4 times 5 mg/kg s.c., 2 hours apart), followed by a 1-week washout period. We then used pharmacological MRI (phMRI) with a methylphenidate (MPH) challenge, as a sensitive and non-invasive in-vivo measure of DAergic function...
2017: PloS One
https://www.readbyqxmd.com/read/28241015/a-concept-for-holistic-whole-body-mri-data-analysis-imiomics
#6
Robin Strand, Filip Malmberg, Lars Johansson, Lars Lind, Magnus Sundbom, Håkan Ahlström, Joel Kullberg
PURPOSE: To present and evaluate a whole-body image analysis concept, Imiomics (imaging-omics) and an image registration method that enables Imiomics analyses by deforming all image data to a common coordinate system, so that the information in each voxel can be compared between persons or within a person over time and integrated with non-imaging data. METHODS: The presented image registration method utilizes relative elasticity constraints of different tissue obtained from whole-body water-fat MRI...
2017: PloS One
https://www.readbyqxmd.com/read/28240946/interictal-diffusion-and-perfusion-magnetic-resonance-imaging-features-of-cats-with-familial-spontaneous-epilepsy
#7
Shunta Mizoguchi, Daisuke Hasegawa, Yuji Hamamoto, Yoshihiko Yu, Takayuki Kuwabara, Aki Fujiwara-Igarashi, Michio Fujita
OBJECTIVE To evaluate the usefulness of diffusion and perfusion MRI of the cerebrum in cats with familial spontaneous epilepsy (FSECs) and identify microstructural and functional deficit zones in affected cats. ANIMALS 19 FSECs and 12 healthy cats. PROCEDURES Diffusion-weighted, diffusion tensor, and perfusion-weighted MRI of the cerebrum were performed during interictal periods in FSECs. Imaging findings were compared between FSECs and control cats. Diffusion (apparent diffusion coefficient and fractional anisotropy) and perfusion (relative cerebral blood volume [rCBV], relative cerebral blood flow [rCBF], and mean transit time) variables were measured bilaterally in the hippocampus, amygdala, thalamus, parietal cortex gray matter, and subcortical white matter...
March 2017: American Journal of Veterinary Research
https://www.readbyqxmd.com/read/28240801/longitudinal-quantitative-mri-assessment-of-cortical-damage-in-multiple-sclerosis-a-pilot-study
#8
René-Maxime Gracien, Sarah C Reitz, Stephanie-Michelle Hof, Vinzenz Fleischer, Amgad Droby, Mathias Wahl, Helmuth Steinmetz, Sergiu Groppa, Ralf Deichmann, Johannes C Klein
PURPOSE: Quantitative MRI (qMRI) allows assessing cortical pathology in multiple sclerosis (MS) on a microstructural level, where cortical damage has been shown to prolong T1 -relaxation time and increase proton density (PD) compared to controls. However, the evolution of these changes in MS over time has not been investigated so far. In this pilot study we used an advanced method for the longitudinal assessment of cortical tissue change in MS patients with qMRI in comparison to cortical atrophy, as derived from conventional MRI...
February 27, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28240794/phase-contrast-mr-flow-imaging-a-tool-to-determine-hepatic-hemodynamics-in-rats-with-a-healthy-fibrotic-or-cirrhotic-liver
#9
Denise Schaffner, Dominik von Elverfeldt, Peter Deibert, Adhara Lazaro, Irmgard Merfort, Lisa Lutz, Jakob Neubauer, Manfred W Baumstark, Wolfgang Kreisel, Wilfried Reichardt
PURPOSE: To test a magnetic resonance (MR) scanning protocol as a noninvasive tool to determine hepatic hemodynamics and to assess the degree of liver fibrosis in an animal model of liver fibrosis and cirrhosis. MATERIALS AND METHODS: Fifty-four male Wistar rats were studied. Thirty-nine received thioacetamide (TAA) in their drinking water for either 12 or 16 weeks. MR measurements were performed using flow-sensitive 2D phase-contrast MRI and a 9.4T preclinical scanner...
February 27, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28240722/brain-correlates-to-facial-motor-imagery-and-its-somatotopy-in-the-primary-motor-cortex
#10
Ramy S Soliman, Sanghoon Lee, Seulgi Eun, Abdalla Z Mohamed, Jeungchan Lee, Eunyoung Lee, Meena M Makary, Seung Min Kathy Lee, Hwa-Jin Lee, Woo Suk Choi, Kyungmo Park
Motor imagery (MI) has attracted increased interest for motor rehabilitation as many studies have shown that MI shares the same neural networks as motor execution (ME). Nevertheless, MI in terms of facial movement has not been studied extensively; thus, in the present study, we investigated shared neural networks between facial motor imagery (FMI) and facial motor execution (FME). In addition, FMI somatotopy within-face was investigated between the forehead and the mouth. Functional MRI was used to examine 34 healthy individuals with ME and MI paradigms for the forehead and the mouth...
February 24, 2017: Neuroreport
https://www.readbyqxmd.com/read/28240665/fdg-pet-to-diagnose-neurolymphomatosis-in-a-case-of-triple-hit-b-cell-lymphoma
#11
Caroline Bund, Céline Heimburger, Philippe Trensz, Cécile Fohrer, Stéphane Kremer, Izzie-Jacques Namer
A 46-year-old man with stage IV triple-hit B-cell lymphoma diagnosed in February 2016 was treated with chemotherapy. He was followed classically with FDG PET/CT, which assessed the complete metabolic response in June 2016. In July 2016, he had autologous stem cell transplantation. Two months later, he underwent an FDG PET/CT for revaluation. It showed intense FDG uptake in the medullary canal from cervical 4 to thoracic 4, bilateral cervical 7 to thoracic 8, and right thoracic 9 to 12 nerve roots, leading to the diagnosis of neurolymphomatosis...
February 24, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28240664/creutzfeldt-jakob-disease-mimicking-alzheimer-disease-and-dementia-with-lewy-bodies-findings-of-fdg-pet-with-3-dimensional-stereotactic-surface-projection
#12
Nobuhiko Miyazawa
A 78-year-old man received a diagnosis of sporadic Creutzfeldt-Jakob disease based on symptoms and findings of MRI, FDG PET, and cerebrospinal fluid markers. PET with 3-dimensional stereotactic surface projection (3D-SSP) showed that the distribution of hypometabolism mimicked that of Alzheimer disease. A 68-year-old woman was treated under a diagnosis of convulsion. Findings of MRI, PET, familial history, and cerebrospinal fluid markers revealed familial Creutzfeldt-Jakob disease. FDG PET with 3D-SSP disclosed that the hypometabolic pattern mimicked that of dementia with Lewy bodies...
February 24, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28240662/long-term-results-of-a-comparative-pet-ct-and-pet-mri-study-of-11-c-acetate-and-18-f-fluorocholine-for-restaging-of-early-recurrent-prostate-cancer
#13
Giorgio Lamanna, Claire Tabouret-Viaud, Olivier Rager, Sandra Jorcano, Hans-Joerg Vees, Yann Seimbille, Habib Zaidi, Osman Ratib, Franz Buchegger, Raymond Miralbell, Thomas Zilli, Valentina Garibotto
PURPOSE: The aims of this study were to assess the intraindividual performance of F-fluorocholine (FCH) and C-acetate (ACE) PET studies for restaging of recurrent prostate cancer (PCa), to correlate PET findings with long-term clinical and imaging follow-up, and to evaluate the impact of PET results on patient management. METHODS: Thirty-three PCa patients relapsing after radical prostatectomy (n = 10, prostate-specific antigen [PSA] ≤3 ng/mL), primary radiotherapy (n = 8, prostate-specific antigen ≤5 ng/mL), or radical prostatectomy + salvage radiotherapy (n = 15) underwent ACE and FCH PET-CT (n = 29) or PET-MRI (n = 4) studies in a randomized sequence 0 to 21 days apart...
February 24, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28240658/monitoring-the-therapy-of-extensive-osseous-sarcoidosis-with-fdg-pet-ct
#14
Hua Yang, Shah Numani, Shuang Liu
FDG PET/CT was performed in a 47-year-old man to evaluate possible malignancy of the spine revealed by MRI. The PET images revealed numerous focal FDG activity throughout the skeletal system. In addition, multiple foci of the increased activity in the mediastinal and hilar nodes were noted, suggestive of sarcoidosis, which was proven following biopsy. Therapy for sarcoidosis was initiated. In the subsequent 4 follow-up FDG PET/CT scans, the activity in both the bones and mediastinal/hilar regions fluctuated...
February 24, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28240635/comparison-of-the-timing-of-hepatic-arterial-phase-and-image-quality-using-test-bolus-and-bolus-tracking-techniques-in-gadolinium-ethoxybenzyl-diethylenetriamine-pentaacetic-acid-enhanced-hepatic-dynamic-magnetic-resonance-imaging
#15
Yuji Iyama, Takeshi Nakaura, Koichi Yokoyama, Masafumi Kidoh, Daisuke Utsunomiya, Seitaro Oda, Tomohiro Namimoto, Yasuyuki Yamashita
OBJECTIVES: The aim of this study was to compare the image quality, the degree of artifacts and the percentage of timing of the optimal hepatic arterial phase (HAP) between test-bolus and bolus-tracking methods on gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid (Gd-EOB-DTPA)-enhanced magnetic resonance imaging (MRI). METHODS: In this prospective study, 60 patients who underwent 3-dimensional dynamic Gd-EOB-DTPA-enhanced hepatic 3-T MRI were enrolled in this study...
February 24, 2017: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/28240514/economic-burden-of-avoidable-hospitalizations-among-patients-with-cancer-at-namazi-hospital-in-shiraz-2013
#16
Nahid Hatam, Tannaz Fanusi, Mehdi Dehghani, Reza Vojdani, Mani Ramzi, Mehrdad Askarian
Introduction: Hospitalization of patients with cancer has a significant economic impact and avoidance where unnecessary has great potential for significant cost savings for patients, individual hospitals and the health system in general. Methods: Demographic, clinical and economical data were collected from medical records in our hospital retrospectively. Oncology clinicians reviewed medical records to categorize each hospitalization as “potentially avoidable” or “not avoidable.” Patient demographic and clinical data were abstracted and quantitative and qualitative analyses were performed to identify patient characteristics and outcomes associated with potentially avoidable hospitalizations...
1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28240422/cerebellar-lobules-and-dentate-nuclei-mirror-cortical-force-related-bold-responses-beyond-all-linear-expectations
#17
Adnan A S Alahmadi, Matteo Pardini, Rebecca S Samson, Karl J Friston, Ahmed T Toosy, Egidio D'Angelo, Claudia A M Gandini Wheeler-Kingshott
The relationship between the BOLD response and an applied force was quantified in the cerebellum using a power grip task. To investigate whether the cerebellum responds in an on/off way to motor demands or contributes to motor responses in a parametric fashion, similarly to the cortex, five grip force levels were investigated under visual feedback. Functional MRI data were acquired in 13 healthy volunteers and their responses were analyzed using a cerebellum-optimized pipeline. This allowed us to evaluate, within the cerebellum, voxelwise linear and non-linear associations between cerebellar activations and forces...
February 27, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/28240421/robo1-polymorphisms-callosal-connectivity-and-reading-skills
#18
Xiaochen Sun, Shuang Song, Xinyu Liang, Yachao Xie, Chenxi Zhao, Yuping Zhang, Hua Shu, Gaolang Gong
The genetic effects on specific behavioral phenotypes are putatively mediated by specific neural functions. It remains unexplored how the axon-guidance-receptor gene ROBO1 influences reading performance through the neural system despite the identification of ROBO1 as a susceptibility gene for dyslexia. To address this issue, the present study recruited a group of children with a wide range of reading abilities. Two previously identified reading-related ROBO1 polymorphisms were genotyped, and diffusion and structural MRI were acquired to measure the fiber microstructure of the corpus callosum (CC), the major white-matter tract that connects inter-hemispheric cortical regions...
February 27, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/28240402/in-vivo-detection-of-lateral-ventral-tier-nigral-degeneration-in-parkinson-s-disease
#19
Daniel E Huddleston, Jason Langley, Jan Sedlacik, Kai Boelmans, Stewart A Factor, Xiaoping P Hu
The objective of this study was to measure neuromelanin-sensitive MRI contrast changes in the lateral-ventral tier of substantia nigra pars compacta in Parkinson's disease (PD). Histopathological studies of PD have demonstrated both massive loss of melanized dopamine neurons and iron accumulation in the substantia nigra pars compacta. Neurodegeneration is most profound in the lateral-ventral tier of this structure. We have previously shown in both healthy controls and individuals with PD that neuromelanin-sensitive MRI and iron-sensitive MRI contrast regions in substantia nigra overlap...
February 27, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/28240392/abnormal-task-driven-neural-oscillations-in-multiple-sclerosis-a-visuomotor-meg-study
#20
Eleanor L Barratt, Prejaas K Tewarie, Margareta A Clarke, Emma L Hall, Penny A Gowland, Peter G Morris, Susan T Francis, Nikos Evangelou, Matthew J Brookes
Multiple sclerosis (MS) is a debilitating disease commonly attributed to degradation of white matter myelin. Symptoms include fatigue, as well as problems associated with vision and movement. Although areas of demyelination in white matter are observed routinely in patients undergoing MRI scans, such measures are often a poor predictor of disease severity. For this reason, it is instructive to measure associated changes in brain function. Widespread white-matter demyelination may lead to delays of propagation of neuronal activity, and with its excellent temporal resolution, magnetoencephalography can be used to probe such delays in controlled conditions (e...
February 27, 2017: Human Brain Mapping
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