Moussa Mansour, Edward P Gerstenfeld, Chinmay Patel, Andrea Natale, William Whang, Frank A Cuoco, Stavros E Mountantonakis, Douglas N Gibson, John D Harding, Scott K Holland, Anitha B Achyutha, Christopher W Schneider, Andrew S Mugglin, Elizabeth M Albrecht, Kenneth M Stein, John W Lehmann, Vivek Y Reddy
BACKGROUND: When it occurs, pulmonary vein (PV) stenosis after atrial fibrillation (AF) ablation is associated with significant morbidity. Even mild-to-moderate PV narrowing may have long-term implications. Unlike thermal ablation energies such as radiofrequency (RF) or cryothermy, pulsed field ablation (PFA) is a non-thermal modality associated with less fibrotic proliferation. Herein, we compared the effects of PFA vs thermal ablation on PV narrowing after AF ablation. METHODS: ADVENT was a multicenter, randomized, single-blind study comparing PFA (pentaspline catheter) with thermal ablation - force-sensing RF or cryoballoon (CB) - to treat drug-refractory paroxysmal AF...
February 2, 2024: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology