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melissa officinalis

Mohammad-Taghi Moradi, Mahmoud Rafieian-Kopaei, Ali Karimi
OBJECTIVE: There are a number of published data indicating in vitro anti-HSV activity of some of Iranian herbal extracts with no systematic review to discuss these results. Therefore, this article was aimed to review and discuss the methods carried out and the phytochemistry and bioactivity of the extracts used and also conclusions provided in these publications. MATERIALS AND METHODS: Published articles both in English (from Medline, Science Direct, EMBASE, Scopus, Pro Quest, Google scholar, Cochrane Library) and in Persian (from SID, Iran Medex and Magiran) databases, from 1966 to October 2014 were incorporated in this review...
September 2016: Avicenna Journal of Phytomedicine
Kristina Ramanauskiene, Raimondas Raudonis, Daiva Majiene
Lemon balm (Melissa officinalis L.) has many biological effects but especially important is its neuroprotective activity. The aim of the study is to produce different extracts of Melissa officinalis and analyse their chemical composition and biological properties on rat glioblastoma C6 cells. Results revealed that rosmarinic acid (RA) is the predominant compound of lemon balm extracts. RA has cytotoxic effect on glioblastoma cells (LC50 290.5 μM after the incubation of 24 h and LC50 171.3 μM after 48 h)...
2016: Oxidative Medicine and Cellular Longevity
Arezoo Saberi, Elham Abbasloo, Gholamreza Sepehri, Mahnaz Yazdanpanah, Ehsan Mirkamandari, Vahid Sheibani, Zohreh Safi
BACKGROUND: Melissa officinalis (MO) has potent antioxidant activity. Recent research has demonstrated the anti-ulcer properties of some medicinal plants through their antioxidant properties. OBJECTIVES: The aim of this study was to evaluate the effects of methanolic extracts of MO on experimental gastric ulcers in rats. MATERIALS AND METHODS: Male Wistar rats (200 - 250 g) were starved for 24 hours prior to the induction of gastric ulceration by either indomethacin (48 mg/kg/oral) or water immersion restraint (WIR) stress...
July 2016: Iranian Red Crescent Medical Journal
Sepide Miraj, Rafieian-Kopaei, Sara Kiani
Melissa officinalis is a plant cultivated in some parts of Iran. The leaves of lemon balm, Melissa officinalis L (Lamiaceae), are used in Iranian folk medicine for their digestive, carminative, antispasmodic, sedative, analgesic, tonic, and diuretic properties, as well as for functional gastrointestinal disorders. This review article was aimed not only to introduce Melissa officinalis (its growth condition, its chemical compounds, and its traditional usages) but also to overview its antioxidant properties in detail...
September 11, 2016: Journal of Evidence-based Complementary & Alternative Medicine
Almudena Pérez-Sánchez, Enrique Barrajón-Catalán, María Herranz-López, Julián Castillo, Vicente Micol
BACKGROUND: Solar ultraviolet (UV) radiation is one of the main causes of a variety of cutaneous disorders, including photoaging and skin cancer. Its UVB component (280-315nm) leads to oxidative stress and causes inflammation, DNA damage, p53 induction and lipid and protein oxidation. Recently, an increase in the use of plant polyphenols with antioxidant and anti-inflammatory properties has emerged to protect human skin against the deleterious effects of sunlight. OBJECTIVE: This study evaluates the protective effects of lemon balm extract (LBE) (Melissa Officinalis, L) and its main phenolic compound rosmarinic acid (RA) against UVB-induced damage in human keratinocytes...
August 4, 2016: Journal of Dermatological Science
Asie Shojaii, Roshanak Ghods, Mehri Abdollahi Fard
BACKGROUND: A few factors such as age, stress, and emotions may lead to impaired learning, memory loss, amnesia, and dementia or threats like schizophrenia and Alzheimer's disease (AD). Iranian traditional medicine (ITM) recommends some herbs and herbal preparations for the treatment or prevention of CNS problems. METHODS: In this study, scientific evidence related to the effectiveness of ITM herbal medicine on memory, learning and AD is reviewed. The scientific evidence of plant efficacy was searched in electronic databases including PubMed, Scopus, SID, Science Direct, and Google Scholar by keywords such as memory, Alzheimer, amnesia, learning and scientific plant names from 1969 to 2014...
May 2016: Iranian Journal of Medical Sciences
Marianna Usai, Aldo Domenico Atzei, Mauro Marchetti
Two species of Melissa are currently present in Sardinia: Melissa officinalis L. and Melissa romana Mill. Our research can only count on a few supported evidences (as reported in Flora Italiana and Moris) and some notes on new stations in Sardinia that give us some information about morphology, distribution, bioecological, and ethnobotanical characteristics of both species. In this paper, we present the results of the research about morphological aspects of M. romana vs. M. officinalis, and their essential oils in different stations at different phenological periods...
August 2016: Chemistry & Biodiversity
Gholamhosein Pourghanbari, Hasan Nili, Afagh Moattari, Ali Mohammadi, Aida Iraji
Lemon balm derivatives are going to acquire a novelty as natural and potent remedy for treatment of viral infections since the influenza viruses are developing resistance to the current antivirals widely. Oseltamivir, Melissa officinalis essential oil (MOEO) and their synergistic efficacy against avian influenza virus (AIV) subtype H9N2 were evaluated in vitro in MDCK cells at different time exposure by using TCID50, HA, Real Time PCR and HI assay. The results showed that MOEO could inhibit replication of AVI through the different virus replication phase (P ≤ 0...
June 2016: Virusdisease
Bernhard Deckers, Tido von Schoen-Angerer, Bernd Voggenreiter, Jan Vagedes
Prolonged postoperative ileus is a common but clinically challenging problem that leads to patient discomfort and prolonged hospitalization; the condition is managed through a multimodular program of supportive measures. In anthroposophic nursing, the management of prolonged postoperative ileus involves additional tools, including external abdominal compresses and massages with plant or silver-containing oils and ointments. We describe 3 typical techniques: Oxalis tincture compresses, Thuja/Argentum ointment compresses, and massage with "Wala Melissenöl" (containing Melissa officinalis, Carvum cari, Foeniculum amari, and Origanum majorana)...
July 2016: Holistic Nursing Practice
Parisa Jandaghi, Mostafa Noroozi, Hamidreza Ardalani, Mahmoud Alipour
OBJECTIVE: Melissa officinalis is a perennial herb from the Lamiaceae family which has shown to have modulating effects on serum lipid profile. The aim of the current study is to explore the effects of M. officinalis supplementation on serum biochemical parameters of patients with borderline hyperlipidemia. METHODS: 58 hyperlipidemic patients were allocated randomly to 2 groups: first group received capsules containing 1000mg M. officinalis leaf powder (MO group), and the second group received placebo capsules (P group) 3 times per day for 2 months...
June 2016: Complementary Therapies in Medicine
Marcin Ozarowski, Przemyslaw L Mikolajczak, Anna Piasecka, Piotr Kachlicki, Radoslaw Kujawski, Anna Bogacz, Joanna Bartkowiak-Wieczorek, Michal Szulc, Ewa Kaminska, Malgorzata Kujawska, Jadwiga Jodynis-Liebert, Agnieszka Gryszczynska, Bogna Opala, Zdzislaw Lowicki, Agnieszka Seremak-Mrozikiewicz, Boguslaw Czerny
Melissa officinalis (MO, English: lemon balm, Lamiaceae), one of the oldest and still most popular aromatic medicinal plants, is used in phytomedicine for the prevention and treatment of nervous disturbances. The aim of our study was to assess the effect of subchronic (28-fold) administration of a 50% ethanol extract of MO leaves (200 mg/kg, p.o.) compared with rosmarinic acid (RA, 10 mg/kg, p.o.) and huperzine A (HU, 0.5 mg/kg, p.o.) on behavioral and cognitive responses in scopolamine-induced rats. The results were linked with acetylcholinesterase (AChE), butyrylcholinesterase (BuChE), and beta-secretase (BACE-1) mRNA levels and AChE and BuChE activities in the hippocampus and frontal cortex of rats...
2016: Evidence-based Complementary and Alternative Medicine: ECAM
Abolfazl Shakeri, Amirhossein Sahebkar, Behjat Javadi
ETHNOPHARMACOLOGICAL RELEVANCE: Melissa officinalis L. is a medicinal plant that has long been used in different ethno-medical systems especially in the European Traditional Medicine and the Iranian Traditional Medicine for the treatment of several diseases. It is also widely used as a vegetable and to add flavor to dishes AIM OF THE REVIEW: This review aimed to provide a summary on the botanical characterization, traditional uses, phytochemistry, pharmacological activities, pharmacokinetics and toxicity of M...
July 21, 2016: Journal of Ethnopharmacology
Carolina Carvalho Bortoletto, Fernanda Cordeiro da Silva, Monica da Consolação Canuto Salgueiro, Lara Jansiski Motta, Lucia Maria Curiki, Raquel Agnelli Mesquita-Ferarri, Kristianne Porta Santos Fernandes, Sandra Kalil Bussadori
[Purpose] Bruxism is a repetitive muscle activity involving the clenching or grinding of one's teeth during sleep or waking hours. Melissa officinalis L. may be employed as a natural therapy due to the sedative, anxiolytic, anti-inflammatory, and anti-spasm properties of the chemical constituents of the essential oil obtained from its leaves. The aim of the present study was to evaluate electromyographic signals in the temporal muscle using the BiteStrip(®) test on children with sleep bruxism before and after therapy with Melissa officinalis L...
March 2016: Journal of Physical Therapy Science
Éva Németh-Zámbori, Zsuzsanna Pluhár, Krisztina Szabó, Mahmoud Malekzadeh, Péter Radácsi, Katalin Inotai, Bonifác Komáromi, Katarzyna Seidler-Lozykowska
A pot experiment was carried out with lemon balm (Melissa officinalis L.) and thyme (Thymus vulgaris L.). Different water supply was applied: 25%, 40% and 70% saturation of soil water capacity (SWC). Morphological traits, biomass and phenolic type active ingredients were investigated. Among the two species, main differences were registered in biomass and TPC. Lower SWC resulted in reduced biomass production of lemon balm, while the applied stress treatments did not effect the biomass of thyme. In lemon balm, highest TPC contents were measured in control plants both in shoots and roots but in thyme, the shoots showed a significantly increased TPC at the 25% SWC conditions...
March 2016: Acta Biologica Hungarica
Saskia Lüde, Sarah Vecchio, Sandra Sinno-Tellier, Aymeric Dopter, Harriet Mustonen, Slavica Vucinic, Birgitta Jonsson, Dieter Müller, Ligia Veras Gimenez Fruchtengarten, Karl Hruby, Elizabeth De Souza Nascimento, Chiara Di Lorenzo, Patrizia Restani, Hugo Kupferschmidt, Alessandro Ceschi
Plant food supplements (PFS) are products of increasing popularity and wide-spread distribution. Nevertheless, information about their risks is limited. To fill this gap, a poisons centres-based study was performed as part of the EU project PlantLIBRA. Multicentre retrospective review of data from selected European and Brazilian poisons centres, involving human cases of adverse effects due to plants consumed as food or as ingredients of food supplements recorded between 2006 and 2010. Ten poisons centres provided a total of 75 cases...
June 2016: Phytotherapy Research: PTR
In Cheul Jeung, Donghyun Jee, Chang-Rae Rho, Seungbum Kang
BACKGROUND: We evaluated the protective effect of ALS-L1023, an extract of Melissa officinalis L. (Labiatae; lemon balm) against oxidative stress-induced apoptosis in human retinal pigment epithelial cells (ARPE-19 cells). METHODS: ARPE-19 cells were incubated with ALS-L1023 for 24 h and then treated with hydrogen peroxide (H2O2). Oxidative stress-induced apoptosis and intracellular generation of reactive oxygen species (ROS) were assessed by flow cytometry. Caspase-3/7 activation and cleaved poly ADP-ribose polymerase (PARP) were measured to investigate the protective role of ALS-L1023 against apoptosis...
2016: International Journal of Medical Sciences
Francisco Cunha, Saulo R Tintino, Fernando Figueredo, Luiz Barros, Antonia E Duarte, Maria Celeste Vega Gomez, Cathia Cecilia Coronel, Mírian Rolón, Nadghia Leite, Celestina E Sobral-Souza, S V Brito, Emily Pansera Waczuc, Aline Augusti Boligon, Margareth Athayde, Jean Paul Kamdem, Henrique Douglas Melo Coutinho, Jéferson Franco
Context Melissa officinalis subsp. inodora Bornm. (Lamiaceae) has been used since ancient times in folk medicine against various diseases, but it has not been investigated against protozoa. Objective To evaluate the activities of M. officinalis against Leishmania braziliensis, Leishmania infantum and Trypanosoma cruzi as well as its cytotoxicity in fibroblast cell line. Materials and methods The fresh leaves were chopped into 1 cm(2) pieces, washed and macerated with 99.9% of ethanol for 72 h at room temperature...
September 2016: Pharmaceutical Biology
Jelena Barbir, Celeste Azpiazu, Francisco R Badenes-Pérez, César Fernández-Quintanilla, José Dorado
Planting floral margins in agricultural landscapes has been shown to increase the abundance of pollinators in agro-ecosystems. However, to create efficient margins, it is necessary to use attractive, not weedy native plants with different blooming periods to prolong the availability of floral resources. Six native perennial plants of the Lamiaceae with different blooming periods were studied in a randomized block design, with the final aim to select the most efficient plants in floral mixtures by studying relationships between their floral phenology, floral density, and attractiveness to pollinators in Central Spain...
April 2016: Journal of Economic Entomology
R P P Fernandes, M A Trindade, F G Tonin, C G Lima, S M P Pugine, P E S Munekata, J M Lorenzo, M P de Melo
The aims of this study were: to evaluate the total equivalent antioxidant capacities (TEAC) and phenolic contents of 13 plants extracts; to select the most promising extracts regarding reducing activity using cluster analysis multivariate statistical technique; and to analyse evaluate sensory acceptance of lamb burgers produced with the most promising natural antioxidants replacing sodium erythorbate. Plant extracts were evaluated regarding TEAC by DPPH(•) and FRAP methods, and total phenolics contents by Folin-Ciocalteau assay...
January 2016: Journal of Food Science and Technology
Valiollah Hajhashemi, Azadeh Safaei
The aim of the present study was to evaluate hypnotic effect of Coriandrum sativum, Ziziphus jujuba, Lavandula angustifolia and Melissa officinalis hydroalcoholic extracts in mice to select the most effective ones for a combination formula. Three doses of the extracts (250, 500 and 1000 mg/kg of C. sativum and Z. jujuba and 200, 400 and 800 mg/kg of L. angustifolia and M. officinalis) were orally administered to male Swiss mice (20-25 g) and one hour later pentobarbital (50 mg/kg, i.p.) was injected to induce sleep...
November 2015: Research in Pharmaceutical Sciences
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