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melissa officinalis

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https://www.readbyqxmd.com/read/27880817/melissa-officinalis-protects-against-doxorubicin-induced-cardiotoxicity-in-rats-and-potentiates-its-anticancer-activity-on-mcf-7-cells
#1
Alaaeldin Ahmed Hamza, Mahguob Mohamed Ahmed, Hanan Mohamed Elwey, Amr Amin
Cardiotoxicity is a limiting factor of doxorubicin (DOX)-based anticancer therapy. Due to its beneficial effects, we investigated whether standardized extract of Melissa officinalis (MO) can attenuate doxorubicin-induced cardiotoxicity and can potentiate the efficacy of DOX against human breast cancer cells. MO was administered orally to male albino rats once daily for 10 consecutive days at doses of 250, 500 and 750 mg/kg b.wt. DOX (15 mg/kg b.wt. i.p.) was administered on the 8th day. MO protected against DOX-induced leakage of cardiac enzymes and histopathological changes...
2016: PloS One
https://www.readbyqxmd.com/read/27825341/essential-oils-in-vitro-activity-against-leishmania-amazonensis-cytotoxicity-and-chemical-composition
#2
Milene Aparecida Andrade, Clênia Dos Santos Azevedo, Flávia Nader Motta, Maria Lucília Dos Santos, Camila Lasse Silva, Jaime Martins de Santana, Izabela M D Bastos
BACKGROUND: The current chemotherapy for cutaneous leishmaniosis (CL) has a series of drug limitations such as toxic side effects, long duration, high costs and drug resistance, which requires the development of new drugs or effective alternatives to the CL treatment. Essential oils (EOs) are complex mixtures of secondary metabolites from various plants. It has been shown that several EOs, or their constituents, have inhibitory activity against protozoa. Thus, this study aims to evaluate the biological activity of different essential oils (EOs) on Leishmania (L...
November 8, 2016: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/27822272/combined-administration-of-melissa-officinalis-and-boswellia-serrata-extracts-in-an-animal-model-of-memory
#3
Mohaddese Mahboubi, Mohsen Taghizadeh, Sayyed Alireza Talaei, Sayyed Mehdi Takht Firozeh, Ali Akbar Rashidi, Omid Reza Tamtaji
BACKGROUND: Boswellia serrata and Melissa officinalis is traditionally used for its memory enhancing effects. OBJECTIVES: In this study, we evaluated the protective effects of combined form of these extracts on memory improvement of scopolamine treated rats by the Morris water maze method. MATERIALS AND METHODS: Two groups (group 1 and 2) of animals were pretreated with combined extracts of B. serrata and M. officinalis (200, 400 mg/Kg body weight) for four weeks and then, 30 minutes before starting the experiment scopolamine was injected (0...
September 2016: Iranian Journal of Psychiatry and Behavioral Sciences
https://www.readbyqxmd.com/read/27815336/assessment-of-neuroprotective-properties-of-melissa-officinalis-in-combination-with-human-umbilical-cord-blood-stem-cells-after-spinal-cord-injury
#4
Seyed Ruhollah Hosseini, Gholamreza Kaka, Mohammad Taghi Joghataei, Mehdi Hooshmandi, Seyed Homayoon Sadraie, Kayvan Yaghoobi, Alireza Mohammadi
INTRODUCTION: The pathophysiology of spinal cord injury (SCI) has a classically bad prognosis. It has been demonstrated that human umbilical cord blood stem cells (hUCBSCs) and Melissa officinalis (MO) are useful for the prevention of neurological disease. METHODS: Thirty-six adult male rats were randomly divided into intact, sham, control (SCI), MO, hUCBSC, and MO-hUCBSC groups. Intraperitoneal injection of MO (150 mg/kg) was commenced 24 hr post-SCI and continued once a day for 14 days...
October 2016: ASN Neuro
https://www.readbyqxmd.com/read/27761420/a-review-study-on-the-effect-of-iranian-herbal-medicines-against-in-vitro-replication-of-herpes-simplex-virus
#5
Mohammad-Taghi Moradi, Mahmoud Rafieian-Kopaei, Ali Karimi
OBJECTIVE: There are a number of published data indicating in vitro anti-HSV activity of some of Iranian herbal extracts with no systematic review to discuss these results. Therefore, this article was aimed to review and discuss the methods carried out and the phytochemistry and bioactivity of the extracts used and also conclusions provided in these publications. MATERIALS AND METHODS: Published articles both in English (from Medline, Science Direct, EMBASE, Scopus, Pro Quest, Google scholar, Cochrane Library) and in Persian (from SID, Iran Medex and Magiran) databases, from 1966 to October 2014 were incorporated in this review...
September 2016: Avicenna Journal of Phytomedicine
https://www.readbyqxmd.com/read/27688825/rosmarinic-acid-and-melissa-officinalis-extracts-differently-affect-glioblastoma-cells
#6
Kristina Ramanauskiene, Raimondas Raudonis, Daiva Majiene
Lemon balm (Melissa officinalis L.) has many biological effects but especially important is its neuroprotective activity. The aim of the study is to produce different extracts of Melissa officinalis and analyse their chemical composition and biological properties on rat glioblastoma C6 cells. Results revealed that rosmarinic acid (RA) is the predominant compound of lemon balm extracts. RA has cytotoxic effect on glioblastoma cells (LC50 290.5 μM after the incubation of 24 h and LC50 171.3 μM after 48 h)...
2016: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/27651945/the-effects-of-methanolic-extract-of-melissa-officinalis-on-experimental-gastric-ulcers-in-rats
#7
Arezoo Saberi, Elham Abbasloo, Gholamreza Sepehri, Mahnaz Yazdanpanah, Ehsan Mirkamandari, Vahid Sheibani, Zohreh Safi
BACKGROUND: Melissa officinalis (MO) has potent antioxidant activity. Recent research has demonstrated the anti-ulcer properties of some medicinal plants through their antioxidant properties. OBJECTIVES: The aim of this study was to evaluate the effects of methanolic extracts of MO on experimental gastric ulcers in rats. MATERIALS AND METHODS: Male Wistar rats (200 - 250 g) were starved for 24 hours prior to the induction of gastric ulceration by either indomethacin (48 mg/kg/oral) or water immersion restraint (WIR) stress...
July 2016: Iranian Red Crescent Medical Journal
https://www.readbyqxmd.com/read/27620926/melissa-officinalis-l-a-review-study-with-an-antioxidant-prospective
#8
Sepide Miraj, Rafieian-Kopaei, Sara Kiani
Melissa officinalis is a plant cultivated in some parts of Iran. The leaves of lemon balm, Melissa officinalis L (Lamiaceae), are used in Iranian folk medicine for their digestive, carminative, antispasmodic, sedative, analgesic, tonic, and diuretic properties, as well as for functional gastrointestinal disorders. This review article was aimed not only to introduce Melissa officinalis (its growth condition, its chemical compounds, and its traditional usages) but also to overview its antioxidant properties in detail...
September 11, 2016: Journal of Evidence-based Complementary & Alternative Medicine
https://www.readbyqxmd.com/read/27528586/lemon-balm-extract-melissa-officinalis-l-promotes-melanogenesis-and-prevents-uvb-induced-oxidative-stress-and-dna-damage-in-a-skin-cell-model
#9
Almudena Pérez-Sánchez, Enrique Barrajón-Catalán, María Herranz-López, Julián Castillo, Vicente Micol
BACKGROUND: Solar ultraviolet (UV) radiation is one of the main causes of a variety of cutaneous disorders, including photoaging and skin cancer. Its UVB component (280-315nm) leads to oxidative stress and causes inflammation, DNA damage, p53 induction and lipid and protein oxidation. Recently, an increase in the use of plant polyphenols with antioxidant and anti-inflammatory properties has emerged to protect human skin against the deleterious effects of sunlight. OBJECTIVE: This study evaluates the protective effects of lemon balm extract (LBE) (Melissa Officinalis, L) and its main phenolic compound rosmarinic acid (RA) against UVB-induced damage in human keratinocytes...
November 2016: Journal of Dermatological Science
https://www.readbyqxmd.com/read/27516676/medicinal-herbs-in-iranian-traditional-medicine-for-learning-and-memory
#10
Asie Shojaii, Roshanak Ghods, Mehri Abdollahi Fard
BACKGROUND: A few factors such as age, stress, and emotions may lead to impaired learning, memory loss, amnesia, and dementia or threats like schizophrenia and Alzheimer's disease (AD). Iranian traditional medicine (ITM) recommends some herbs and herbal preparations for the treatment or prevention of CNS problems. METHODS: In this study, scientific evidence related to the effectiveness of ITM herbal medicine on memory, learning and AD is reviewed. The scientific evidence of plant efficacy was searched in electronic databases including PubMed, Scopus, SID, Science Direct, and Google Scholar by keywords such as memory, Alzheimer, amnesia, learning and scientific plant names from 1969 to 2014...
May 2016: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/27449960/a-comparative-study-on-essential-oil-intraspecific-and-seasonal-variations-melissa%C3%A2-romana-mill-and-melissa%C3%A2-officinalis-l-from-sardinia
#11
Marianna Usai, Aldo Domenico Atzei, Mauro Marchetti
Two species of Melissa are currently present in Sardinia: Melissa officinalis L. and Melissa romana Mill. Our research can only count on a few supported evidences (as reported in Flora Italiana and Moris) and some notes on new stations in Sardinia that give us some information about morphology, distribution, bioecological, and ethnobotanical characteristics of both species. In this paper, we present the results of the research about morphological aspects of M. romana vs. M. officinalis, and their essential oils in different stations at different phenological periods...
August 2016: Chemistry & Biodiversity
https://www.readbyqxmd.com/read/27366768/antiviral-activity-of-the-oseltamivir-and-melissa-officinalis-l-essential-oil-against-avian-influenza-a-virus-h9n2
#12
Gholamhosein Pourghanbari, Hasan Nili, Afagh Moattari, Ali Mohammadi, Aida Iraji
Lemon balm derivatives are going to acquire a novelty as natural and potent remedy for treatment of viral infections since the influenza viruses are developing resistance to the current antivirals widely. Oseltamivir, Melissa officinalis essential oil (MOEO) and their synergistic efficacy against avian influenza virus (AIV) subtype H9N2 were evaluated in vitro in MDCK cells at different time exposure by using TCID50, HA, Real Time PCR and HI assay. The results showed that MOEO could inhibit replication of AVI through the different virus replication phase (P ≤ 0...
June 2016: Virusdisease
https://www.readbyqxmd.com/read/27309410/external-nursing-applications-in-the-supportive-management-of-prolonged-postoperative-ileus-description-of-interventions-and-case-report
#13
Bernhard Deckers, Tido von Schoen-Angerer, Bernd Voggenreiter, Jan Vagedes
Prolonged postoperative ileus is a common but clinically challenging problem that leads to patient discomfort and prolonged hospitalization; the condition is managed through a multimodular program of supportive measures. In anthroposophic nursing, the management of prolonged postoperative ileus involves additional tools, including external abdominal compresses and massages with plant or silver-containing oils and ointments. We describe 3 typical techniques: Oxalis tincture compresses, Thuja/Argentum ointment compresses, and massage with "Wala Melissenöl" (containing Melissa officinalis, Carvum cari, Foeniculum amari, and Origanum majorana)...
July 2016: Holistic Nursing Practice
https://www.readbyqxmd.com/read/27261994/lemon-balm-a-promising-herbal-therapy-for-patients-with-borderline-hyperlipidemia-a-randomized-double-blind-placebo-controlled-clinical-trial
#14
Parisa Jandaghi, Mostafa Noroozi, Hamidreza Ardalani, Mahmoud Alipour
OBJECTIVE: Melissa officinalis is a perennial herb from the Lamiaceae family which has shown to have modulating effects on serum lipid profile. The aim of the current study is to explore the effects of M. officinalis supplementation on serum biochemical parameters of patients with borderline hyperlipidemia. METHODS: 58 hyperlipidemic patients were allocated randomly to 2 groups: first group received capsules containing 1000mg M. officinalis leaf powder (MO group), and the second group received placebo capsules (P group) 3 times per day for 2 months...
June 2016: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/27239217/influence-of-the-melissa-officinalis-leaf-extract-on-long-term-memory-in-scopolamine-animal-model-with-assessment-of-mechanism-of-action
#15
Marcin Ozarowski, Przemyslaw L Mikolajczak, Anna Piasecka, Piotr Kachlicki, Radoslaw Kujawski, Anna Bogacz, Joanna Bartkowiak-Wieczorek, Michal Szulc, Ewa Kaminska, Malgorzata Kujawska, Jadwiga Jodynis-Liebert, Agnieszka Gryszczynska, Bogna Opala, Zdzislaw Lowicki, Agnieszka Seremak-Mrozikiewicz, Boguslaw Czerny
Melissa officinalis (MO, English: lemon balm, Lamiaceae), one of the oldest and still most popular aromatic medicinal plants, is used in phytomedicine for the prevention and treatment of nervous disturbances. The aim of our study was to assess the effect of subchronic (28-fold) administration of a 50% ethanol extract of MO leaves (200 mg/kg, p.o.) compared with rosmarinic acid (RA, 10 mg/kg, p.o.) and huperzine A (HU, 0.5 mg/kg, p.o.) on behavioral and cognitive responses in scopolamine-induced rats. The results were linked with acetylcholinesterase (AChE), butyrylcholinesterase (BuChE), and beta-secretase (BACE-1) mRNA levels and AChE and BuChE activities in the hippocampus and frontal cortex of rats...
2016: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/27167460/melissa-officinalis-l-a-review-of-its-traditional-uses-phytochemistry-and-pharmacology
#16
REVIEW
Abolfazl Shakeri, Amirhossein Sahebkar, Behjat Javadi
ETHNOPHARMACOLOGICAL RELEVANCE: Melissa officinalis L. is a medicinal plant that has long been used in different ethno-medical systems especially in the European Traditional Medicine and the Iranian Traditional Medicine for the treatment of several diseases. It is also widely used as a vegetable and to add flavor to dishes AIM OF THE REVIEW: This review aimed to provide a summary on the botanical characterization, traditional uses, phytochemistry, pharmacological activities, pharmacokinetics and toxicity of M...
July 21, 2016: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27134350/evaluation-of-electromyographic-signals-in-children-with-bruxism-before-and-after-therapy-with-melissa-officinalis-l-a-randomized-controlled-clinical-trial
#17
Carolina Carvalho Bortoletto, Fernanda Cordeiro da Silva, Monica da Consolação Canuto Salgueiro, Lara Jansiski Motta, Lucia Maria Curiki, Raquel Agnelli Mesquita-Ferarri, Kristianne Porta Santos Fernandes, Sandra Kalil Bussadori
[Purpose] Bruxism is a repetitive muscle activity involving the clenching or grinding of one's teeth during sleep or waking hours. Melissa officinalis L. may be employed as a natural therapy due to the sedative, anxiolytic, anti-inflammatory, and anti-spasm properties of the chemical constituents of the essential oil obtained from its leaves. The aim of the present study was to evaluate electromyographic signals in the temporal muscle using the BiteStrip(®) test on children with sleep bruxism before and after therapy with Melissa officinalis L...
March 2016: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/26960357/effect-of-water-supply-on-growth-and-polyphenols-of-lemon-balm-melissa-officinalis-l-and-thyme-thymus-vulgaris-l
#18
Éva Németh-Zámbori, Zsuzsanna Pluhár, Krisztina Szabó, Mahmoud Malekzadeh, Péter Radácsi, Katalin Inotai, Bonifác Komáromi, Katarzyna Seidler-Lozykowska
A pot experiment was carried out with lemon balm (Melissa officinalis L.) and thyme (Thymus vulgaris L.). Different water supply was applied: 25%, 40% and 70% saturation of soil water capacity (SWC). Morphological traits, biomass and phenolic type active ingredients were investigated. Among the two species, main differences were registered in biomass and TPC. Lower SWC resulted in reduced biomass production of lemon balm, while the applied stress treatments did not effect the biomass of thyme. In lemon balm, highest TPC contents were measured in control plants both in shoots and roots but in thyme, the shoots showed a significantly increased TPC at the 25% SWC conditions...
March 2016: Acta Biologica Hungarica
https://www.readbyqxmd.com/read/26948409/adverse-effects-of-plant-food-supplements-and-plants-consumed-as-food-results-from-the-poisons-centres-based-plantlibra-study
#19
Saskia Lüde, Sarah Vecchio, Sandra Sinno-Tellier, Aymeric Dopter, Harriet Mustonen, Slavica Vucinic, Birgitta Jonsson, Dieter Müller, Ligia Veras Gimenez Fruchtengarten, Karl Hruby, Elizabeth De Souza Nascimento, Chiara Di Lorenzo, Patrizia Restani, Hugo Kupferschmidt, Alessandro Ceschi
Plant food supplements (PFS) are products of increasing popularity and wide-spread distribution. Nevertheless, information about their risks is limited. To fill this gap, a poisons centres-based study was performed as part of the EU project PlantLIBRA. Multicentre retrospective review of data from selected European and Brazilian poisons centres, involving human cases of adverse effects due to plants consumed as food or as ingredients of food supplements recorded between 2006 and 2010. Ten poisons centres provided a total of 75 cases...
June 2016: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/26941573/melissa-officinalis-l-extracts-protect-human-retinal-pigment-epithelial-cells-against-oxidative-stress-induced-apoptosis
#20
In Cheul Jeung, Donghyun Jee, Chang-Rae Rho, Seungbum Kang
BACKGROUND: We evaluated the protective effect of ALS-L1023, an extract of Melissa officinalis L. (Labiatae; lemon balm) against oxidative stress-induced apoptosis in human retinal pigment epithelial cells (ARPE-19 cells). METHODS: ARPE-19 cells were incubated with ALS-L1023 for 24 h and then treated with hydrogen peroxide (H2O2). Oxidative stress-induced apoptosis and intracellular generation of reactive oxygen species (ROS) were assessed by flow cytometry. Caspase-3/7 activation and cleaved poly ADP-ribose polymerase (PARP) were measured to investigate the protective role of ALS-L1023 against apoptosis...
2016: International Journal of Medical Sciences
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