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https://www.readbyqxmd.com/read/29684670/evaluation-of-the-bisap-scoring-system-in-prognostication-of-acute-pancreatitis-a-prospective-observational-study
#1
Sumitra Hagjer, Nitesh Kumar
INTRODUCTION: Severe acute pancreatitis has a high mortality and its early identification is important for management and risk stratification. The bedside index for severity in acute pancreatitis (BISAP) is a simple scoring system done at admission which predicts the severity of pancreatitis. Procalcitonin is an inflammatory marker which is raised very early and helps in early prediction of the severity of disease. This study aims to evaluate the BISAP score and Procalcitonin in prognostication of acute pancreatitis...
April 20, 2018: International Journal of Surgery
https://www.readbyqxmd.com/read/29680294/klinefelter-syndrome-the-effects-of-early-androgen-therapy-on-competence-and-behavioral-phenotype
#2
REVIEW
Ryan Flannigan, Premal Patel, Darius A Paduch
INTRODUCTION: Klinefelter syndrome (KS) is the result of sex chromosome aneuploidy most often characterized as 47,XXY. The typical features of KS include tall stature, gynecomastia, small firm testicles, hypergonadotropic hypogonadism, and infertility. However, abnormalities in neurodevelopment, cognition, and social and behavioral functioning also can be present. The abnormalities in neurodevelopment are believed to be due in part to androgen deficiency during early development and puberty...
April 18, 2018: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/29678558/influence-factors-of-sexual-activity-for-internal-migrants-in-china
#3
Junguo Zhang, Junqing Wu, Yuyan Li, Ying Zhou, Yiran Li, Rui Zhao, Yuanming Shi, Zheng Li, Wei Huang, Jian Chen
BACKGROUND: Sexual frequency is associated with the quality of life. China's internal migrants that are sexually active are more likely to participate in sexual behavior. However, less work has been undertaken to assess the sexual frequency and its predictors in migrants. AIM: This study seeks to explore which factors were related to sexual frequency in migrants and how the association varies with different levels of sexual frequency. METHODS: A total of 10,834 men and 4,928 women aged 20-49 years from 5 cities in China were enrolled by multi-stage sampling during August 2013-August 2015...
April 17, 2018: Sexual Medicine
https://www.readbyqxmd.com/read/29678557/improvements-to-the-vulva-vestibule-urethral-meatus-and-vagina-in-women-treated-with-ospemifene-for-moderate-to-severe-dyspareunia-a-prospective-vulvoscopic-pilot-study
#4
Sue W Goldstein, Ashley G Winter, Irwin Goldstein
INTRODUCTION: Ospemifene, an oral selective estrogen receptor modulator approved for the treatment of mild to moderate dyspareunia from menopause, has been shown to moderate sexual pain and vaginal epithelial cell characteristics. However, no prospective vulvoscopic studies have been performed. AIM: To examine, in menopausal women taking ospemifene 60 mg daily, changes to the vulva, vestibule, urethral meatus, and vaginal region over 20 weeks using vulvoscopy in a prospective open-label pilot study...
April 17, 2018: Sexual Medicine
https://www.readbyqxmd.com/read/29678474/the-impact-of-body-awareness-on-women-s-sexual-health-a-comprehensive-review
#5
REVIEW
Brooke N Seal, Cindy M Meston
INTRODUCTION: Body awareness has been linked to female sexual response in laboratory manipulation studies and is used in clinical settings to ameliorate sexual difficulties. AIM: To evaluate and review the literature on body awareness and female sexual function. METHODS: A literature review was conducted through PsycInfo, PsycARTICLES, and PubMed using terms such as body awareness and sexual function. A manual search also was conducted using reference lists...
April 17, 2018: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/29676932/exoplanet-biosignatures-a-framework-for-their-assessment
#6
David C Catling, Joshua Krissansen-Totton, Nancy Y Kiang, David Crisp, Tyler D Robinson, Shiladitya DasSarma, Andrew J Rushby, Anthony Del Genio, William Bains, Shawn Domagal-Goldman
Finding life on exoplanets from telescopic observations is an ultimate goal of exoplanet science. Life produces gases and other substances, such as pigments, which can have distinct spectral or photometric signatures. Whether or not life is found with future data must be expressed with probabilities, requiring a framework of biosignature assessment. We present a framework in which we advocate using biogeochemical "Exo-Earth System" models to simulate potential biosignatures in spectra or photometry...
April 20, 2018: Astrobiology
https://www.readbyqxmd.com/read/29676927/woodpeckers-and-diamonds-some-aspects-of-evolutionary-convergence-in-astrobiology
#7
Milan M Ćirković
Jared Diamond's argument against extraterrestrial intelligence from evolutionary contingency is subjected to critical scrutiny. As with the earlier arguments of George Gaylord Simpson, it contains critical loopholes that lead to its unraveling. From the point of view of the contemporary debates about biological evolution, perhaps the most contentious aspect of such arguments is their atemporal and gradualist usage of the space of all possible biological forms (morphospace). Such usage enables the translation of the adaptive value of a trait into the probability of its evolving...
April 20, 2018: Astrobiology
https://www.readbyqxmd.com/read/29675742/specific-c%C3%AE-c-bond-cleavage-of-%C3%AE-carbon-centered-radical-peptides-produced-by-matrix-assisted-laser-desorption-ionization-mass-spectrometry
#8
Keishiro Nagoshi, Mariko Yamakoshi, Kenya Sakamoto, Mitsuo Takayama
Radical-driven dissociation (RDD) of hydrogen-deficient peptide ions [M - H + H]·+ has been examined using matrix-assisted laser dissociation/ionization in-source decay mass spectrometry (MALDI-ISD MS) with the hydrogen-abstracting matrices 4-nitro-1-naphthol (4,1-NNL) and 5-nitrosalicylic acid (5-NSA). The preferential fragment ions observed in the ISD spectra include N-terminal [a] + ions and C-terminal [x]+ , [y + 2]+ , and [w]+ ions which imply that β-carbon (Cβ)-centered radical peptide ions [M - Hβ + H]·+ are predominantly produced in MALDI conditions...
April 19, 2018: Journal of the American Society for Mass Spectrometry
https://www.readbyqxmd.com/read/29672134/metabolism-and-biodegradation-of-spacecraft-cleaning-reagents-by-strains-of-spacecraft-associated-acinetobacter
#9
Rakesh Mogul, Gregory A Barding, Sidharth Lalla, Sooji Lee, Steve Madrid, Ryan Baki, Mahjabeen Ahmed, Hania Brasali, Ivonne Cepeda, Trevor Gornick, Shawn Gunadi, Nicole Hearn, Chirag Jain, Eun Jin Kim, Thi Nguyen, Vinh Bao Nguyen, Alex Oei, Nicole Perkins, Joseph Rodriguez, Veronica Rodriguez, Gautam Savla, Megan Schmitz, Nicholas Tedjakesuma, Jillian Walker
Spacecraft assembly facilities are oligotrophic and low-humidity environments, which are routinely cleaned using alcohol wipes for benchtops and spacecraft materials, and alkaline detergents for floors. Despite these cleaning protocols, spacecraft assembly facilities possess a persistent, diverse, dynamic, and low abundant core microbiome, where the Acinetobacter are among the dominant members of the community. In this report, we show that several spacecraft-associated Acinetobacter metabolize or biodegrade the spacecraft cleaning reagents of ethanol (ethyl alcohol), 2-propanol (isopropyl alcohol), and Kleenol 30 (floor detergent) under ultraminimal conditions...
April 19, 2018: Astrobiology
https://www.readbyqxmd.com/read/29666354/double-trisomy-xxx-21-karyotype-in-a-six-year-old-girl-with-down-phenotype
#10
Laura Daniela Vergara-Mendez, Claudia Talero-Gutiérrez, Alberto Velez-Van-Meerbeke
We describe a case of a six-year-old girl who presents multiple dysmorphic features characteristic of Down's syndrome. She has a significant general developmental delay, with a score that correspond to 32 months of developmental age. This delay is especially in language, with a very scant vocabulary. She communicates with some hand sign words or pointing, although her auditory responses in hearing test were normal. Two previous karyotype studies showed 47, XXX, +21 anomalies. This double trisomy is a rare condition described in isolated cases in the literature and none of these refers to the developmental aspects of these children (Balwan et al...
March 2018: Journal of Genetics
https://www.readbyqxmd.com/read/29664686/enhanced-microbial-survivability-in-subzero-brines
#11
Jacob Heinz, Janosch Schirmack, Alessandro Airo, Samuel P Kounaves, Dirk Schulze-Makuch
It is well known that dissolved salts can significantly lower the freezing point of water and thus extend habitability to subzero conditions. However, most investigations thus far have focused on sodium chloride as a solute. In this study, we report on the survivability of the bacterial strain Planococcus halocryophilus in sodium, magnesium, and calcium chloride or perchlorate solutions at temperatures ranging from +25°C to -30°C. In addition, we determined the survival rates of P. halocryophilus when subjected to multiple freeze/thaw cycles...
April 17, 2018: Astrobiology
https://www.readbyqxmd.com/read/29661690/the-history-of-testosterone-and-the-evolution-of-its-therapeutic-potential
#12
REVIEW
Abraham Morgentaler, Abdulmaged Traish
INTRODUCTION: Testosterone therapy has been controversial since its synthesis in the 1930s to the present day. Testosterone's history provides depth and context for current controversies. AIM: To review the history of testosterone therapy from its initial synthesis in the 1930s to the modern day. METHODS: Expert review of the literature. MAIN OUTCOME MEASURES: Impactful events in the history of testosterone. RESULTS: By the 1940s there was already a fascinating literature that described the many symptomatic benefits of testosterone therapy that are recognized today...
April 13, 2018: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/29661689/cardiometabolic-risk-and-female-sexuality-part-ii-understanding-and-overcoming-gender-differences-the-key-role-of-an-adequate-methodological-approach
#13
REVIEW
Elisa Maseroli, Irene Scavello, Linda Vignozzi
INTRODUCTION: Although basic science and clinical research indicate that the vascular physiopathology of male and female sexual dysfunction (FSD) is similar, to date the association between FSD and cardiovascular (CV) diseases has been only marginally explored. AIM: To discuss the potential reasons for differences in the role of CV diseases and risk factors in sexual function in women vs men in the 2nd part of a 2-part review. METHODS: A thorough literature search of peer-reviewed publications on the topic was performed using the PubMed database...
April 13, 2018: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/29661646/physical-activity-to-improve-erectile-function-a-systematic-review-of-intervention-studies
#14
REVIEW
Helle Gerbild, Camilla Marie Larsen, Christian Graugaard, Kristina Areskoug Josefsson
INTRODUCTION: The leading cause of erectile dysfunction (ED) is arterial dysfunction, with cardiovascular disease as the most common comorbidity. Therefore, ED is typically linked to a web of closely interrelated cardiovascular risk factors such as physical inactivity, obesity, hypertension, and metabolic syndrome. Physical activity (PA) has proved to be a protective factor against erectile problems, and it has been shown to improve erectile function for men affected by vascular ED. This systematic review estimated the levels of PA needed to decrease ED for men with physical inactivity, obesity, hypertension, metabolic syndrome, and/or manifest cardiovascular diseases...
April 13, 2018: Sexual Medicine
https://www.readbyqxmd.com/read/29658977/a-systematic-review-and-meta-analysis-of-procalcitonin-as-a-marker-of-postoperative-orthopedic-infections
#15
Ross B Ingber, Abduljabbar Alhammoud, Daniel P Murray, Roby Abraham, Anant Dixit, Qais Naziri, Ghalib Ahmed, Carl B Paulino, William P Urban, Chad Craig, Aditya V Maheshwari, Bassel G Diebo
Procalcitonin is a serologic marker that increases in response to inflammatory stimuli, especially those of bacterial origin. Postoperative orthopedic periprosthetic infections are often difficult to diagnose. This study systematically reviewed the literature to evaluate the statistical measures of performance of procalcitonin as a marker of postoperative orthopedic infection. This study showed that procalcitonin has a weighted pooled sensitivity of 67.3%, specificity of 69.4%, positive likelihood ratio of 1...
April 16, 2018: Orthopedics
https://www.readbyqxmd.com/read/29656131/postoperative-treatment-following-open-incisional-hernia-repair-a-survey-and-a-review-of-literature
#16
Christoph Paasch, Stefan Anders, Martin W Strik
INTRODUCTION: Incisional hernias of the abdominal wall are frequent complication after laparotomy (9-20%). Open incisional hernia repair with sublay mesh placement (SMP) on the posterior rectus sheath is described as being a sufficient method for repairing incisional hernia. In order to ensure wound healing and to therefore prevent recurrence, carrying an abdominal binder (AB) or a pressure dressing (PD) and physical rest for a certain time is the common postoperative recommendation, though the evidence for post-operative treatment is low...
April 12, 2018: International Journal of Surgery
https://www.readbyqxmd.com/read/29651906/return-to-sport-rates-in-physically-active-individuals-six-months-after-arthroscopy-for-femoroacetabular-impingement-syndrome
#17
Kathryn R Glaws, Thomas J Ellis, Timothy E Hewett, Stephanie L Di Stasi
CONTEXT: Six-months is the expected timeframe to return to sport (RTS) after hip arthroscopy for femoroacetabular impingement syndrome (FAIS). OBJECTIVE: The primary aims of this study were to (1) report the RTS rate of physically active individuals six-months after arthroscopic surgery for FAIS, and (2) compare the self-reported hip function between those who were able to RTS versus those who had not. DESIGN: cohort study. SETTING: XXX...
April 13, 2018: Journal of Sport Rehabilitation
https://www.readbyqxmd.com/read/29651094/drain-away-the-pain
#18
Brontë Chandrasekara
Efficacy of first aid treatment of acute apical abscess in an NHS emergency clinic 2018; 224: 523-527 http://dx.doi.org/10.1038/sj.bdj.2018.xxx.
April 13, 2018: British Dental Journal
https://www.readbyqxmd.com/read/29649668/laparoscopic-vs-open-restorative-proctocolectomy-with-ipaa-for-ulcerative-colitis-impact-of-surgical-technique-on-creating-a-well-functioning-pouch
#19
Michela Mineccia, Francesca Cravero, Paolo Massucco, Luca Portigliotti, Franco Bertolino, Marco Daperno, Alessandro Ferrero
BACKGROUND: Patients with ulcerative colitis are often young, and proctocolectomy with restorative ileo-pouch anal anastomosis is a crucial act that can improve or worsen the quality of the rest of their lives. The literature is scant on long-term functional outcomes after laparoscopy. The purpose of this study was to investigate results in terms of pouch function after standardized total laparoscopic technique compared with open intervention. MATERIALS AND METHODS: This was a retrospective comparative study...
April 9, 2018: International Journal of Surgery
https://www.readbyqxmd.com/read/29628218/effects-of-sex-hormones-and-age-on-brain-volume-in-post-menopausal-women
#20
Gwang-Won Kim, Kwangsung Park, Gwang-Woo Jeong
BACKGROUND: Investigation of the effect of sex hormones on the brain volume in women provides a unique opportunity to examine menopause-related morphometric alterations. AIM: To evaluate brain morphological alterations in post-menopausal women using voxel-based morphometry and its correlations with sex hormone levels. METHODS: 20 Pre-menopausal women and 20 post-menopausal women underwent structural MRI. OUTCOMES: T1-weighted magnetic resonance data were acquired and serum sex hormones including total estrogen, estriol, estradiol (E2), follicle-stimulating hormone, free testosterone, SHBG, and luteinizing hormone were measured...
April 5, 2018: Journal of Sexual Medicine
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