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https://www.readbyqxmd.com/read/27912029/how-to-establish-a-bioregenerative-life-support-system-for-long-term-crewed-missions-to-the-moon-or-mars
#1
Yuming Fu, Leyuan Li, Beizhen Xie, Chen Dong, Mingjuan Wang, Boyang Jia, Lingzhi Shao, Yingying Dong, Shengda Deng, Hui Liu, Guanghui Liu, Bojie Liu, Dawei Hu, Hong Liu
To conduct crewed simulation experiments of bioregenerative life support systems on the ground is a critical step for human life support in deep-space exploration. An artificial closed ecosystem named Lunar Palace 1 was built through integrating efficient higher plant cultivation, animal protein production, urine nitrogen recycling, and bioconversion of solid waste. Subsequently, a 105-day, multicrew, closed integrative bioregenerative life support systems experiment in Lunar Palace 1 was carried out from February through May 2014...
December 2, 2016: Astrobiology
https://www.readbyqxmd.com/read/27912028/formation-and-persistence-of-brine-on-mars-experimental-simulations-throughout-the-diurnal-cycle-at-the-phoenix-landing-site
#2
E Fischer, G M Martínez, N O Rennó
In the last few years, water ice and salts capable of melting this ice and producing liquid saline water (brine) have been detected on Mars. Moreover, indirect evidence for brine has been found in multiple areas of the planet. Here, we simulate full diurnal cycles of temperature and atmospheric water vapor content at the Phoenix landing site for the first time and show experimentally that, in spite of the low Mars-like chamber temperature, brine forms minutes after the ground temperature exceeds the eutectic temperature of salts in contact with water ice...
December 2, 2016: Astrobiology
https://www.readbyqxmd.com/read/27909486/misleading-advertising-by-attorneys-concerning-noacs-is-adversely-costly-to-our-patients-and-our-society
#3
EDITORIAL
James A, Reiffel M D
Over the past five years, "ambulance-chasing" attorneys have aggressively advertised for patients who have bled on a new oral anticoagulant (NOAC) or their family members. It is an infrequent day when American consumers do not see a TV advertisement saying something like: "Have you or a loved-one had a serious bleeding event while taking [fill in the NOAC]? If so, you may be entitled to monetary compensation. Call XXX, attorneys at law, and we will get you the money you deserve."
February 2016: Journal of Atrial Fibrillation
https://www.readbyqxmd.com/read/27905827/modeling-pn2-through-geological-time-implications-for-planetary-climates-and-atmospheric-biosignatures
#4
E E Stüeken, M A Kipp, M C Koehler, E W Schwieterman, B Johnson, R Buick
Nitrogen is a major nutrient for all life on Earth and could plausibly play a similar role in extraterrestrial biospheres. The major reservoir of nitrogen at Earth's surface is atmospheric N2, but recent studies have proposed that the size of this reservoir may have fluctuated significantly over the course of Earth's history with particularly low levels in the Neoarchean-presumably as a result of biological activity. We used a biogeochemical box model to test which conditions are necessary to cause large swings in atmospheric N2 pressure...
December 1, 2016: Astrobiology
https://www.readbyqxmd.com/read/27901343/colonization-of-snow-by-microorganisms-as-revealed-using-miniature-raman-spectrometers-possibilities-for-detecting-carotenoids-of-psychrophiles-on-mars
#5
Jan Jehlička, Adam Culka, Linda Nedbalová
We tested the potential of a miniaturized Raman spectrometer for use in field detection of snow algae pigments. A miniature Raman spectrometer, equipped with an excitation laser at 532 nm, allowed for the detection of carotenoids in cells of Chloromonas nivalis and Chlamydomonas nivalis at different stages of their life cycle. Astaxanthin, the major photoprotective pigment, was detected in algal blooms originating in snows at two alpine European sites that differed in altitude (Krkonoše Mts., Czech Republic, 1502 m a...
November 30, 2016: Astrobiology
https://www.readbyqxmd.com/read/27896447/novel-extended-sequons-of-human-n-glycosylation-sites-improve-the-precision-of-qualitative-predictions-an-alignment-free-study-of-pattern-recognition-using-protdcal-protein-features
#6
Yasser B Ruiz-Blanco, Yovani Marrero-Ponce, Enrique García-Hernández, James Green
N-Glycosylation is a common post-translational modification that plays an important role in the proper folding and function of many proteins. This modification is largely dependent on the presence of a sequence motif called a "sequon" defined as Asn-Xxx-Ser/Thr. However, evidence has shown that the presence of such a "sequon" is insufficient to determine the occurrence of N-glycosylation with high precision. This study aims to elucidate patterns that can more accurately predict N-glycosylation sites in human proteins...
November 28, 2016: Amino Acids
https://www.readbyqxmd.com/read/27893284/biomarkers-and-metabolic-patterns-in-the-sediments-of-evolving-glacial-lakes-as-a-proxy-for-planetary-lake-exploration
#7
Víctor Parro, Yolanda Blanco, Fernando Puente-Sánchez, Luis A Rivas, Mercedes Moreno-Paz, Alex Echeverría, Guillermo Chong-Díaz, Cecilia Demergasso, Nathalie A Cabrol
Oligotrophic glacial lakes in the Andes Mountains serve as models to study the effects of climate change on natural biological systems. The persistent high UV regime and evolution of the lake biota due to deglaciation make Andean lake ecosystems potential analogues in the search for life on other planetary bodies. Our objective was to identify microbial biomarkers and metabolic patterns that represent time points in the evolutionary history of Andean glacial lakes, as these may be used in long-term studies as microscale indicators of climate change processes...
November 28, 2016: Astrobiology
https://www.readbyqxmd.com/read/27892807/the-effect-of-early-life-stress-on-the-cognitive-phenotype-of-children-with-an-extra-x-chromosome-47-xxy-47-xxx
#8
Sophie van Rijn, Petra Barneveld, Mie-Jef Descheemaeker, Jacques Giltay, Hanna Swaab
Studies on gene-environment interactions suggest that some individuals may be more susceptible to life adversities than others due to their genetic profile. This study assesses whether or not children with an extra X chromosome are more vulnerable to the negative impact of early life stress on cognitive functioning than typically-developing children. A total of 50 children with an extra X chromosome and 103 non-clinical controls aged 9 to 18 years participated in the study. Cognitive functioning in domains of language, social cognition and executive functioning were assessed...
November 28, 2016: Child Neuropsychology: a Journal on Normal and Abnormal Development in Childhood and Adolescence
https://www.readbyqxmd.com/read/27875626/developing-a-research-agenda-for-reducing-the-stigma-of-addictions-part-ii-lessons-from-the-mental-health-stigma-literature
#9
REVIEW
Patrick W Corrigan, Georg Schomerus, Valery Shuman, Dana Kraus, Debbie Perlick, Autumn Harnish, Magdalena Kulesza, Kathleen Kane-Willis, Sang Qin, David Smelson
BACKGROUND AND OBJECTIVES: Although advocates and providers identify stigma as a major factor in confounding the recovery of people with SUDs, research on addiction stigma is lacking, especially when compared to the substantive literature examining the stigma of mental illness. METHODS: A comprehensive review of the stigma literature that yielded empirically supported concepts and methods from the mental health arena was contrasted with the much smaller and mostly descriptive findings from the addiction field...
November 22, 2016: American Journal on Addictions
https://www.readbyqxmd.com/read/27875012/growth-of-nurse-prescribing-competence-facilitators-and-barriers-during-education
#10
H Hopia, A Karhunen, J Heikkilä
OBJECTIVE: To describe facilitators and barriers in relation to the growth of nurse prescribing competence from the perspective of the nurses studying in a prescribing programme. BACKGROUND: The number of nurses enrolled in a nurse prescribing programme is rapidly increasing in XXX. However, few studies on nurse prescribing education are available and therefore research is needed, particularly from the point of view of nurses studying in the programme. DESIGN: The descriptive, qualitative study used the text of student online learning diaries as data during a 14-month prescribing programme...
November 22, 2016: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/27870556/twenty-species-of-hypobarophilic-bacteria-recovered-from-diverse-soils-exhibit-growth-under-simulated-martian-conditions-at-0-7%C3%A2-kpa
#11
Andrew C Schuerger, Wayne L Nicholson
Bacterial growth at low pressure is a new research area with implications for predicting microbial activity in clouds and the bulk atmosphere on Earth and for modeling the forward contamination of planetary surfaces like Mars. Here, we describe experiments on the recovery and identification of 20 species of bacterial hypobarophiles (def., growth under hypobaric conditions of approximately 1-2 kPa) in 10 genera capable of growth at 0.7 kPa. Hypobarophilic bacteria, but not archaea or fungi, were recovered from diverse soils, and high numbers of hypobarophiles were recovered from Arctic and Siberian permafrost soils...
November 21, 2016: Astrobiology
https://www.readbyqxmd.com/read/27870548/onboard-science-insights-and-vehicle-dynamics-from-scale-model-trials-of-the-titan-mare-explorer-time-capsule-at-laguna-negra-chile
#12
Ralph D Lorenz, Nathalie A Cabrol
A scale model of the proposed Titan Mare Explorer capsule was deployed at the Planetary Lake Lander field site at Laguna Negra, Chile. The tests served to calibrate models of wind-driven drift of the capsule and to understand its attitude motion in the wave field, as well as to identify dynamic and acoustic signatures of shoreline approach. This information enables formulation of onboard trigger criteria for near-shore science data acquisition. Key Words: Titan-Vehicle dynamics-Science autonomy-Lake. Astrobiology 17, xxx-xxx...
November 21, 2016: Astrobiology
https://www.readbyqxmd.com/read/27845810/communication-between-acute-care-hospitals-and-skilled-nursing-facilities-during-care-transitions-a-retrospective-chart-review
#13
Cheryl Jusela, Laura Struble, Nancy Ambrose Gallagher, Richard W Redman, Rosemary A Ziemba
HOW TO OBTAIN CONTACT HOURS BY READING THIS ARTICLE INSTRUCTIONS XX contact hours will be awarded by Villanova University College of Nursing upon successful completion of this activity. A contact hour is a unit of measurement that denotes 60 minutes of an organized learning activity. This is a learner-based activity. Villanova University College of Nursing does not require submission of your answers to the quiz. A contact hour certificate will be awarded once you register, pay the registration fee, and complete the evaluation form online at http://goo...
November 15, 2016: Journal of Gerontological Nursing
https://www.readbyqxmd.com/read/27833193/sonnet-xxx-love-dignity-and-dying
#14
E Wesley Ely
All of us in medicine who care for patients who are chronically critically ill, dying of incurable illnesses, will be faced with discussions about the value of their lives and about the appropriateness of ongoing supportive care. Such discussions are good and true, and they must always be done within the context of the sanctity of every human life and the promise of God that we are His children, each and every one of us. In this article, I explore the end-of-life path of a patient with amyotrophic lateral sclerosis (ALS) and the courageous faith that she demonstrated in the face of her illness...
May 2016: Linacre Quarterly
https://www.readbyqxmd.com/read/27827540/meteorites-and-the-rna-world-a-thermodynamic-model-of-nucleobase-synthesis-within-planetesimals
#15
Ben K D Pearce, Ralph E Pudritz
The possible meteorite parent body origin of Earth's pregenetic nucleobases is substantiated by the guanine (G), adenine (A), and uracil (U) measured in various meteorites. Cytosine (C) and thymine (T), however, are absent in meteorites, making the emergence of an RNA and later RNA/DNA/protein world problematic. We investigated the meteorite parent body (planetesimal) origin of all nucleobases by computationally modeling 18 reactions that potentially contribute to nucleobase formation in such environments. Out of this list, we identified the two most important reactions for each nucleobase and found that these involve small molecules such as HCN, CO, NH3, and water that ultimately arise from the protoplanetary disks in which planetesimals are built...
November 2016: Astrobiology
https://www.readbyqxmd.com/read/27827533/fluctuation-analysis-of-redox-potential-to-distinguish-microbial-fe-ii-oxidation
#16
A M L Enright, F G Ferris
We developed a novel method for distinguishing abiotic and biological iron oxidation in liquid media using oxidation-reduction (redox) potential time series data. The instrument and processing algorithm were tested by immersing the tip of a Pt electrode with an Ag-AgCl reference electrode into an active iron-oxidizing biofilm in a groundwater discharge zone, as well as in two abiotic systems: a killed sample and a chemical control from the same site. We used detrended fluctuation analysis to characterize average root mean square fluctuation behavior, which was distinct in the live system...
November 2016: Astrobiology
https://www.readbyqxmd.com/read/27799275/influences-of-brain-size-sex-and-sex-chromosome-complement-on-the-architecture-of-human-cortical-folding
#17
Ari M Fish, Arnaud Cachia, Clara Fischer, Catherine Mankiw, P K Reardon, Liv S Clasen, Jonathan D Blumenthal, Deanna Greenstein, Jay N Giedd, Jean-François Mangin, Armin Raznahan
Gyrification is a fundamental property of the human cortex that is increasingly studied by basic and clinical neuroscience. However, it remains unclear if and how the global architecture of cortical folding varies with 3 interwoven sources of anatomical variation: brain size, sex, and sex chromosome dosage (SCD). Here, for 375 individuals spanning 7 karyotype groups (XX, XY, XXX, XYY, XXY, XXYY, XXXXY), we use structural neuroimaging to measure a global sulcation index (SI, total sulcal/cortical hull area) and both determinants of sulcal area: total sulcal length and mean sulcal depth...
October 31, 2016: Cerebral Cortex
https://www.readbyqxmd.com/read/27792417/the-pale-orange-dot-the-spectrum-and-habitability-of-hazy-archean-earth
#18
Giada Arney, Shawn D Domagal-Goldman, Victoria S Meadows, Eric T Wolf, Edward Schwieterman, Benjamin Charnay, Mark Claire, Eric Hébrard, Melissa G Trainer
Recognizing whether a planet can support life is a primary goal of future exoplanet spectral characterization missions, but past research on habitability assessment has largely ignored the vastly different conditions that have existed in our planet's long habitable history. This study presents simulations of a habitable yet dramatically different phase of Earth's history, when the atmosphere contained a Titan-like, organic-rich haze. Prior work has claimed a haze-rich Archean Earth (3.8-2.5 billion years ago) would be frozen due to the haze's cooling effects...
November 2016: Astrobiology
https://www.readbyqxmd.com/read/27779803/developing-a-research-agenda-for-understanding-the-stigma-of-addictions-part-i-lessons-from-the-mental-health-stigma-literature
#19
REVIEW
Patrick Corrigan, Georg Schomerus, Valery Shuman, Dana Kraus, Debbie Perlick, Autumn Harnish, Magdalena Kulesza, Kathleen Kane-Willis, Sang Qin, David Smelson
BACKGROUND AND OBJECTIVES: Although advocates and providers identify stigma as a major factor in confounding the recovery of people with SUDs, research on addiction stigma is lacking, especially when compared to the substantive literature examining the stigma of mental illness. METHODS: A review of key studies from the stigma literature that yielded empirically supported concepts and methods from the mental health arena was contrasted with the much smaller and mostly descriptive findings from the addiction field...
October 25, 2016: American Journal on Addictions
https://www.readbyqxmd.com/read/27753986/sy-09-4-public-policies-to-reduce-salt-in-processed-foods-how-they-may-correlate-with-improvement-in-blood-pressure-control-and-reduced-cardiovascular-mortality
#20
Norm Campbell
Hypertension is the second leading global risk for death and disability after unhealthy diets. Amongst dietary risks, excess dietary salt (sodium) is the leading risk. As dietary sodium increases, blood pressure increases linearly. In meta-analyses of higher quality cohort studies and in a meta-analysis of randomized controlled trials, higher dietary sodium is linearly associated with increased cardiovascular disease. There are an estimated xxxx deaths and xxx DALYs in 2013 from excess dietary sodium. The World Health Organization has a recommended sodium (salt) intake of less than 2000 mg (5 g)/day with the World Health Assembly setting a voluntary target of a 30% reduction by 2025...
September 2016: Journal of Hypertension
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