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https://www.readbyqxmd.com/read/28202344/testosterone-replacement-therapy-and-components-of-the-metabolic-syndrome
#1
REVIEW
James Anaissie, Natalie H Roberts, Ping Wang, Faysal A Yafi
INTRODUCTION: The prevalence of metabolic syndrome (MetS) is rapidly increasing in the United States and, because of its strong association with male hypogonadism, has become a significant topic of interest in the sexual medicine community. At the center of this conversation is the efficacy and safety of testosterone replacement therapy (TRT) as a therapeutic option for HG and MetS. AIM: To provide a review of the current literature pertaining to TRT and MetS. METHODS: A thorough literature review was performed to review the relation between TRT and MetS using the PubMed online database from 1976 through 2016 with the keywords testosterone, hypogonadism, metabolic syndrome, and testosterone therapy...
February 12, 2017: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/28202323/cumulative-adverse-childhood-experiences-and-sexual-satisfaction-in-sex-therapy-patients-what-role-for-symptom-complexity
#2
Noémie Bigras, Natacha Godbout, Martine Hébert, Stéphane Sabourin
INTRODUCTION: Patients consulting for sexual difficulties frequently present additional personal or relational disorders and symptoms. This is especially the case when they have experienced cumulative adverse childhood experiences (CACEs), which are associated with symptom complexity. CACEs refer to the extent to which an individual has experienced an accumulation of different types of adverse childhood experiences including sexual, physical, and psychological abuse; neglect; exposure to inter-parental violence; and bullying...
February 12, 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28202322/sexual-health-competencies-for-undergraduate-medical-education-in-north-america
#3
Carey Roth Bayer, Kristen L Eckstrand, Gail Knudson, Jean Koehler, Scott Leibowitz, Perry Tsai, Jamie L Feldman
INTRODUCTION: The number of hours spent teaching sexual health content and skills in medical education continues to decrease despite the increase in sexual health issues faced by patients across the lifespan. In 2012 and 2014, experts across sexuality disciplines convened for the Summits on Medical School Education and Sexual Health to strategize and recommend approaches to improve sexual health education in medical education systems and practice settings. One of the summit recommendations was to develop sexual health competencies that could be implemented in undergraduate medical education curricula...
February 12, 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28202321/anxiety-and-depression-among-sexual-minority-women-and-men-in-sweden-is-the-risk-equally-spread-within-the-sexual-minority-population
#4
Charlotte Björkenstam, Emma Björkenstam, Gunnar Andersson, Susan Cochran, Kyriaki Kosidou
INTRODUCTION: Sexual minority individuals have a higher risk of anxiety and depression compared with heterosexuals. However, whether the higher risk is spread equally across the sexual minority population is not clear. AIM: To investigate the association between sexual orientation and self-reported current anxiety and a history of diagnosis of depression, paying particular attention to possible subgroup differences in risks within the sexual minority population, stratified by sex and to examine participants' history of medical care for anxiety disorders and depression...
February 12, 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28202320/the-women-s-empower-survey-identifying-women-s-perceptions-on-vulvar-and-vaginal-atrophy-and-its-treatment
#5
Sheryl A Kingsberg, Michael Krychman, Shelli Graham, Brian Bernick, Sebastian Mirkin
INTRODUCTION: Vulvar and vaginal atrophy (VVA) affects up to two thirds of postmenopausal women, but most symptomatic women do not receive prescription therapy. AIM: To evaluate postmenopausal women's perceptions of VVA and treatment options for symptoms in the Women's EMPOWER survey. METHODS: The Rose Research firm conducted an internet survey of female consumers provided by Lightspeed Global Market Insite. Women at least 45 years of age who reported symptoms of VVA and residing in the United States were recruited...
February 12, 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28202319/the-women-s-empower-survey-women-s-knowledge-and-awareness-of-treatment-options-for-vulvar-and-vaginal-atrophy-remains-inadequate
#6
Michael Krychman, Shelli Graham, Brian Bernick, Sebastian Mirkin, Sheryl A Kingsberg
INTRODUCTION: Postmenopausal women's knowledge about vulvar and vaginal atrophy (VVA) and available treatment options has historically been inadequate. Recent direct-to-consumer marketing and educational efforts would have been expected to increase awareness and treatment options. AIM: To compare results of the Women's EMPOWER survey with other available VVA surveys to assess progress in women's understanding and approaches to treatment of VVA. METHODS: The Women's EMPOWER survey, an internet-based survey of US women with VVA symptoms, assessed women's awareness of VVA and their behaviors and attitudes associated with symptom treatment...
February 12, 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28177270/biosignature-preservation-and-detection-in-mars-analog-environments
#7
Lindsay E Hays, Heather V Graham, David J Des Marais, Elisabeth M Hausrath, Briony Horgan, Thomas M McCollom, M Niki Parenteau, Sally L Potter-McIntyre, Amy J Williams, Kennda L Lynch
This review of material relevant to the Conference on Biosignature Preservation and Detection in Mars Analog Environments summarizes the meeting materials and discussions and is further expanded upon by detailed references to the published literature. From this diverse source material, there is a detailed discussion on the habitability and biosignature preservation potential of five primary analog environments: hydrothermal spring systems, subaqueous environments, subaerial environments, subsurface environments, and iron-rich systems...
February 8, 2017: Astrobiology
https://www.readbyqxmd.com/read/28162947/fty720-supplementation-partially-improves-erectile-dysfunction-in-rats-with-streptozotocin-induced-type-1-diabetes-through-inhibition-of-endothelial-dysfunction-and-corporal-fibrosis
#8
Kai Cui, Yajun Ruan, Tao Wang, Ke Rao, Zhong Chen, Shaogang Wang, Jihong Liu
INTRODUCTION: Erectile dysfunction (ED) in patients with diabetes mellitus (DM) seriously affects their quality of life. However, these patients show a poor effect rate for oral phosphodiesterase type 5 inhibitors. Thus, new treatment methods are urgently needed. Fingolimod hydrochloride (FTY720) was approved in 2010 for the treatment of patients with the relapsing-remitting form of multiple sclerosis. AIM: To investigate whether FTY720 supplementation could ameliorate ED induced by DM (DMED)...
February 2, 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28160377/novel-gene-sequence-markers-for-isolate-tracking-within-monilinia-fructicola-lesions
#9
M E Dowling, G Schnabel, H G Boatwright, S E Everhart
: Dowling, M.E., Schnabel, G., Boatwright, H.G., and Everhart, S.E. xxxx. Novel gene-sequence markers for isolate tracking within Monilinia fructicola lesions. Pest Management Science xxx:xxx-xxx. BACKGROUND: Monilinia fructicola is a diverse pathogen of pome and stone fruits that causes severe economic losses each year. However, little is known about inoculum flow within or between orchards and pathogen establishment in an orchard, because few methods exist for detecting diversity or tracking isolates over time...
February 3, 2017: Pest Management Science
https://www.readbyqxmd.com/read/28152155/bullying-in-senior-living-facilities-perspectives-of-long-term-care-staff
#10
Felicia J Andresen, Jeffrey A Buchanan
HOW TO OBTAIN CONTACT HOURS BY READING THIS ARTICLE INSTRUCTIONS XX contact hours will be awarded by Villanova University College of Nursing upon successful completion of this activity. A contact hour is a unit of measurement that denotes 60 minutes of an organized learning activity. This is a learner-based activity. Villanova University College of Nursing does not require submission of your answers to the quiz. A contact hour certificate will be awarded once you register, pay the registration fee, and complete the evaluation form online at http://goo...
February 2, 2017: Journal of Gerontological Nursing
https://www.readbyqxmd.com/read/28152153/aspects-of-self-and-identity-in-narrations-about-recent-events-communication-with-individuals-with-alzheimer-s-disease-enabled-by-a-digital-photograph-diary
#11
Eva Karlsson, Karin Zingmark, Karin Axelsson, Stefan Sävenstedt
HOW TO OBTAIN CONTACT HOURS BY READING THIS ARTICLE INSTRUCTIONS XX contact hours will be awarded by Villanova University College of Nursing upon successful completion of this activity. A contact hour is a unit of measurement that denotes 60 minutes of an organized learning activity. This is a learner-based activity. Villanova University College of Nursing does not require submission of your answers to the quiz. A contact hour certificate will be awarded once you register, pay the registration fee, and complete the evaluation form online at http://goo...
February 2, 2017: Journal of Gerontological Nursing
https://www.readbyqxmd.com/read/28151696/survival-dna-integrity-and-ultrastructural-damage-in-antarctic-cryptoendolithic-eukaryotic-microorganisms-exposed-to-ionizing-radiation
#12
Claudia Pacelli, Laura Selbmann, Laura Zucconi, Marina Raguse, Ralf Moeller, Igor Shuryak, Silvano Onofri
Life dispersal between planets, planetary protection, and the search for biosignatures are main topics in astrobiology. Under the umbrella of the STARLIFE project, three Antarctic endolithic microorganisms, the melanized fungus Cryomyces antarcticus CCFEE 515, a hyaline strain of Umbilicaria sp. (CCFEE 6113, lichenized fungus), and a Stichococcus sp. strain (C45A, green alga), were exposed to high doses of space-relevant gamma radiation ((60)Co), up to 117.07 kGy. After irradiation survival, DNA integrity and ultrastructural damage were tested...
February 2, 2017: Astrobiology
https://www.readbyqxmd.com/read/28151694/the-effects-of-hze-particles-%C3%AE-and-x-ray-radiation-on-the-survival-and-genetic-integrity-of-halobacterium-salinarum-nrc-1-halococcus-hamelinensis-and-halococcus-morrhuae
#13
Stefan Leuko, Petra Rettberg
Three halophilic archaea, Halobacterium salinarum NRC-1, Halococcus hamelinensis, and Halococcus morrhuae have been exposed to different regimes of simulated outer space ionizing radiation. Strains were exposed to high-energy heavy ion (HZE) particles, namely iron and argon ions, as well as to γ radiation ((60)Co) and X-rays, and the survival and the genetic integrity of the 16S rRNA gene were evaluated. Exposure to 1 kGy of argon or iron ions at the Heavy Ion Medical Accelerator in Chiba (HIMAC) facility at the National Institute for Radiological Sciences (NIRS) in Japan did not lead to a detectable loss in viability; only after exposure to 2 kGy of iron ions a decline in survival was observed...
February 2, 2017: Astrobiology
https://www.readbyqxmd.com/read/28151691/starlife-an-international-campaign-to-study-the-role-of-galactic-cosmic-radiation-in-astrobiological-model-systems
#14
Ralf Moeller, Marina Raguse, Stefan Leuko, Thomas Berger, Christine Elisabeth Hellweg, Akira Fujimori, Ryuichi Okayasu, Gerda Horneck
In-depth knowledge regarding the biological effects of the radiation field in space is required for assessing the radiation risks in space. To obtain this knowledge, a set of different astrobiological model systems has been studied within the STARLIFE radiation campaign during six irradiation campaigns (2013-2015). The STARLIFE group is an international consortium with the aim to investigate the responses of different astrobiological model systems to the different types of ionizing radiation (X-rays, γ rays, heavy ions) representing major parts of the galactic cosmic radiation spectrum...
February 2, 2017: Astrobiology
https://www.readbyqxmd.com/read/28151689/evaluation-of-the-resistance-of-chroococcidiopsis-spp-to-sparsely-and-densely-ionizing-irradiation
#15
Cyprien Verseux, Mickael Baqué, Riccardo Cifariello, Claudia Fagliarone, Marina Raguse, Ralf Moeller, Daniela Billi
Studying the resistance of cyanobacteria to ionizing radiation provides relevant information regarding astrobiology-related topics including the search for life on Mars, lithopanspermia, and biological life-support systems. Here, we report on the resistance of desert cyanobacteria of the genus Chroococcidiopsis, which were exposed (as part of the STARLIFE series of experiments) in both hydrated and dried states to ionizing radiation with different linear energy transfer values (0.2 to 200 keV/μm). Irradiation with up to 1 kGy of He or Si ions, 2 kGy of Fe ions, 5 kGy of X-rays, or 11...
February 2, 2017: Astrobiology
https://www.readbyqxmd.com/read/28143716/sexual-distress-and-sexual-problems-during-pregnancy-associations-with-sexual-and-relationship-satisfaction
#16
Sarah A Vannier, Natalie O Rosen
INTRODUCTION: Sexual problems are common during pregnancy, but the proportion of pregnant women who experience sexual distress is unknown. In non-pregnant samples, sexual distress is associated with lower sexual and relationship satisfaction. AIM: To identify the proportion of women experiencing sexual distress during pregnancy and to compare the sexual and relationship satisfaction of women who report sexual distress during pregnancy with that of women without distress...
January 28, 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28143706/critical-analysis-of-satisfaction-assessment-after-penile-prosthesis-surgery
#17
REVIEW
William Akakpo, Miguel A Pineda, Arthur L Burnett
INTRODUCTION: Penile prosthesis implantation is believed to provide a high level of patient satisfaction. The International Index of Erectile Function and the Erectile Dysfunction Inventory of Treatment Satisfaction are two validated questionnaires that have been used to assess this outcome. The lack of a tool specifically validated for patients undergoing penile prosthesis surgery has led to the use of heterogeneous methods to assess patient satisfaction. AIM: To review the assessment of patient satisfaction with penile prosthesis surgery according to several factors...
January 28, 2017: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/28137251/autism-spectrum-disorder-associated-with-49-xyyyy-case-report-and-review-of-the-literature
#18
Caroline Demily, Alice Poisson, Elodie Peyroux, Valérie Gatellier, Alain Nicolas, Caroline Rigard, Caroline Schluth-Bolard, Damien Sanlaville, Massimiliano Rossi
BACKGROUND: Sex chromosome aneuploidies occur in approximately one in 420 live births. The most frequent abnormalities are 45,X (Turner syndrome), 47,XXX (triple X), 47,XXY (Klinefelter syndrome), and 47,XYY. The prevalence of males with more than one extra sex chromosome (e.g. 48,XXYY or 48,XXXY) is less common. However, the literature provides little information about the cognitive and behavioural phenotype and the natural history of the disease. We report the clinical, neurocognitive, social cognitive and psychiatric characterization of a patient with 49,XYYYY syndrome...
January 31, 2017: BMC Medical Genetics
https://www.readbyqxmd.com/read/28131322/safety-tolerability-and-sensorimotor-effects-of-extended-release-dalfampridine-in-adults-with-cerebral-palsy-a-pilot-study
#19
Francois Bethoux, Ali Fatemi, Eileen Fowler, Christina Marciniak, Angeli Mayadev, Joel Waksman, Kathleen Zackowski, Gustavo Suarez, Andrew R Blight, Adrian L Rabinowicz, Enrique Carrazana
PURPOSE: The goal of this study was to evaluate the safety and tolerability of dalfampridine extended release (D-ER) in a pilot study of adults with cerebral palsy (CP) and limited ambulatory ability, and to explore drug effects on sensorimotor function. METHODS: An initial double-blind, single-dose crossover study was performed in 11 individuals randomized 1:1 to receive D-ER (10 mg) or placebo, followed by a 2-day washout period and the opposite treatment, with evaluation for safety and tolerability...
January 25, 2017: Clinical Therapeutics
https://www.readbyqxmd.com/read/28130018/the-relationship-between-self-reported-sexually-explicit-media-consumption-and-sexual-risk-behaviors-among-men-who-have-sex-with%C3%A2-men-in-china
#20
Yin Xu, Yong Zheng, Qazi Rahman
INTRODUCTION: Previous studies have indicated that viewing sexually explicit media (SEM) might be associated with sexual risk behaviors in men who have sex with men (MSM). However, most prior research has not explored this association cross-culturally or the potential influence that important covariates might have on the association. AIM: To explore the association between self-reports of viewing SEM depicting various sexual risk behaviors and engagement in sexual risk behaviors after controlling for relevant covariates in MSM in China...
January 24, 2017: Journal of Sexual Medicine
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