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Varalaxmi Bhavani Nannaka, Dmitry Lvovsky
: Angina pectoris in pregnancy is unusual and Prinzmetal's angina is much rarer. It accounts for 2% of all cases of angina. It is caused by vasospasm, but the mechanism of spasm is unknown but has been linked with hyperthyroidism in some studies. Patients with thyrotoxicosis-induced acute myocardial infarction are unusual and almost all reported cases have been associated with Graves' disease. Human chorionic gonadotropin hormone-induced hyperthyroidism occurs in about 1.4% of pregnant women, mostly when hCG levels are above 70-80 000 IU/L...
2016: Endocrinology, Diabetes & Metabolism Case Reports
Fahad Javed, Stephen Ramee
Patients with coronary artery disease (CAD) are destined to lifelong antiplatelet therapy in form of aspirin (acetylsalicylic acid) alone, or in combination with other P2Y2 inhibitors. Proton pump inhibitors (PPIs) are the preferred agents for the treatment and prophylaxis of gastrointestinal injury associated with nonsteroidal anti-inflammatory drug or acetylsalicylic acid or both,(1) but recent data has raised questions about their association with negative cardiovascular events. We report 2 cases of patients with known CAD presented with chest pain mimicking angina pectoris that successfully resolved on discontinuation of the PPIs...
July 2016: Current Problems in Cardiology
Ulrich Tebbe
No abstract text is available yet for this article.
August 2016: Deutsche Medizinische Wochenschrift
Tommaso Gori, Udo Sechtem, Thomas Münzel
No abstract text is available yet for this article.
January 25, 2016: JACC. Cardiovascular Interventions
Daniel Fitousi
Composite faces combine the top half of one face with the bottom half of another to create a compelling illusion of a new face. Evidence for holistic processing with composite faces comes primarily from a matching procedure in a selective attention task. In the present study, a dual-task approach has been employed to study whether composite faces reflect genuine holistic (i.e., fusion of parts) or non-holistic processing strategies (i.e., switching, resource sharing). This has been accomplished by applying the Attention Operation Characteristic methodology (AOC, Sperling & Melchner, 1978a, 1978b) and cross-contingency correlations (Bonnel & Prinzmetal, 1998) to composite faces...
March 2016: Cognition
Alex Mitko, William Prinzmetal, Michael Esterman, Alexandra List
An illusory conjunction is a feature binding error wherein a person incorrectly combines features from two different objects. Behavioral investigations have implicated spatial attention in successful feature binding, suggesting that failures of spatial attention lead to illusory conjunctions. We examined this phenomenon using electroencephalography (EEG) to identify neural markers of binding successes and failures. We hypothesized that EEG markers of covert spatial attention, the N1 and N2pc, would be greater when features were correctly bound compared with illusory conjunctions...
2015: Journal of Vision
Naveen Chandra Ganiga Sanjeeva, Ranjan K Shetty, Sumit Agarwal
Prinzmetal variant angina or vasospastic angina is a clinical syndrome characterised by episodic chest pain and transient reversible ST segment changes in ECG. The aetiology and treatment of the condition are quite different compared to those of conventional coronary artery disease. The crux of the problem in variant angina patients remains the diagnosis, especially if coexisting coronary artery disease is present. Timely diagnosis not only helps relieve symptoms, it also prevents complications such as ventricular tachycardia...
2015: BMJ Case Reports
Thomas M Kinfe, Bogdan Pintea
OBJECTIVE: To describe an unusual case of combined neuropathic and ischemia-induced chronic pain in a patient who was treated with one high thoracic paddle lead. BACKGROUND: To the best of our knowledge, the use of spinal cord stimulation (SCS) utilizing a single lead as a treatment strategy for combined Prinzmetal angina, a cardiac ischemia-induced disturbance of nociceptive perception, and diabetic neuropathy of the lower limbs has rarely been described. CASE REPORT: The underlying pain conditions and SCS technique used to treat both types of pain-Prinzmetal angina and lower-limb diabetic neuropathy-in a 73-year-old patient experiencing medical or interventional refractory complex pain syndrome are described...
March 2016: Journal of Neurological Surgery. Part A, Central European Neurosurgery
William Prinzmetal, Kelly L Whiteford, Joseph L Austerweil, Ayelet N Landau
Navigating through our perceptual environment requires constant selection of behaviorally relevant information and irrelevant information. Spatial cues guide attention to information in the environment that is relevant to the current task. How does the amount of information provided by a location cue and irrelevant information influence the deployment of attention and what are the processes underlying this effect? To address these questions, we used a spatial cueing paradigm to measure the relationship between cue predictability (measured in bits of information) and the voluntary attention effect, the benefit in reaction time (RT) because of cueing a target...
October 2015: Journal of Experimental Psychology. Human Perception and Performance
Dale Murdoch, Priyanka Dhillon, Selvanayagam Niranjan
Prinzmetal's variant angina describes chest pain secondary to reversible coronary artery vasospasm in the context of both diseased and non-diseased coronary arteries. Symptoms typically occur when the patient is at rest and are associated with transient ST-segment elevation. Acute episodes respond to glyceryl trinitrate, but myocardial infarction and other potentially fatal complications can occur, and long-term management can be challenging. Although it is not well understood, the underlying mechanism appears to involve a combination of endothelial damage and vasoactive mediators...
May 2015: Singapore Medical Journal
Mingzhu Xu, Xiangjun Yang
Variant angina pectoris, also called Prinzmetal's angina, is a syndrome caused by vasospasms of the coronary arteries. It can lead to myocardial infarction, ventricular arrhythmias, atrioventricular block and even sudden cardiac death. We report the case of a 53 year-old male patient with recurrent episodes of chest pain and arrhythmias in the course of related variant angina pectoris. It is likely that the reperfusion following myocardial ischemia was responsible for the ventricular fibrillation while the ST-segment returned to the baseline...
July 2015: Journal of Electrocardiology
Kathrin Machalke, Peter Bramlage, Karin Bramlage, Ulrich Tebbe
Medical history | We report on a 44-year-old patient with recurrent thoracic pain occurring 4 months apart. The patient complained about intense thoracic pain and acute dyspnoea in the morning. In the course of the second presentation the anamnesis revealed that the previous day the patient had consumed an entire bag of licorice (200 g). Investigations | The blood pressure was 90/65 mmHg, heart rate 68 beats / min. Neither the performed ECG nor the transthoracic echocardiography showed abnormalities...
April 2015: Deutsche Medizinische Wochenschrift
Ahmet Gündeş, Ahmet Çelik, İsmail Türkay Özcan, Ahmet Çamsarı
Variant angina, which is also referred to as prinzmetal or coronary vasospastic angina, is a clinical entity characterized by episodes of angina pectoris, usually at rest and often between midnight and early morning, in association with ST-segment elevation on the electrocardiogram. Angina is usually caused by focal spasm of a major coronary artery resulting in a high-grade obstruction, and myocardial infarction may develop in some cases. We report a prinzmetal angina which caused ventricular fibrillation and cardiac arrest in an 18-week pregnant woman...
March 2015: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
Antonio Bayés de Luna, Iwona Cygankiewicz, Adrian Baranchuk, Miquel Fiol, Yochai Birnbaum, Kjell Nikus, Diego Goldwasser, Javier Garcia-Niebla, Samuel Sclarovsky, Hein Wellens, Günter Breithardt
BACKGROUND: We will focus our attention in this article in the ECG changes of classical Prinzmetal angina that occur during occlusive proximal coronary spasm usually in patients with normal or noncritical coronary stenosis. RESULTS: The most important ECG change during a focal proximal coronary spasm is in around 50% of cases the appearance of peaked and symmetrical T wave that is followed, if the spasm persist, by progressive ST-segment elevation that last for a few minutes, and later progressively resolve...
September 2014: Annals of Noninvasive Electrocardiology
Vincenzo Sucato, Angela Sansone, Salvatore Evola, Giuseppina Novo, Giuseppe Coppola, Egle Corrado, Antonino Rotolo, Giuseppe Andolina, Salvatore Novo, Pasquale Assennato
No abstract text is available yet for this article.
January 2015: Coronary Artery Disease
Michael H Smolensky, Francesco Portaluppi, Roberto Manfredini, Ramon C Hermida, Ruana Tiseo, Linda L Sackett-Lundeen, Erhard L Haus
Various medical conditions, disorders, and syndromes exhibit predictable-in-time diurnal and 24 h patterning in the signs, symptoms, and grave nonfatal and fatal events, e.g., respiratory ones of viral and allergic rhinorrhea, reversible (asthma) and non-reversible (bronchitis and emphysema) chronic obstructive pulmonary disease, cystic fibrosis, high altitude pulmonary edema, and decompression sickness; cardiac ones of atrial premature beats and tachycardia, paroxysmal atrial fibrillation, 3rd degree atrial-ventricular block, paroxysmal supraventricular tachycardia, ventricular premature beats, ventricular tachyarrhythmia, symptomatic and non-symptomatic angina pectoris, Prinzmetal vasospastic variant angina, acute (non-fatal and fatal) incidents of myocardial infarction, sudden cardiac arrest, in-bed sudden death syndrome of type-1 diabetes, acute cardiogenic pulmonary edema, and heart failure; vascular and circulatory system ones of hypertension, acute orthostatic postprandial, micturition, and defecation hypotension/syncope, intermittent claudication, venous insufficiency, standing occupation leg edema, arterial and venous branch occlusion of the eye, menopausal hot flash, sickle cell syndrome, abdominal, aortic, and thoracic dissections, pulmonary thromboembolism, and deep venous thrombosis, and cerebrovascular transient ischemic attack and hemorrhagic and ischemic stroke...
June 2015: Sleep Medicine Reviews
Deepak L Bhatt
No abstract text is available yet for this article.
June 2014: Harvard Heart Letter: From Harvard Medical School
Michael Ruisi, Phillip Ruisi, Hugo Rosero, Paul Schweitzer
Prinzmetal angina or vasospastic angina is a clinical phenomenon that is often transient and self-resolving. Clinically it is associated with ST elevations on the electrocardiogram, and initially it may be difficult to differentiate from an acute myocardial infarction. The vasospasm induced in this setting occurs in normal or mildly to moderately diseased vessels and can be triggered by a number of etiologies including smoking, changes in autonomic activity, or drug ingestion. While the ischemia induced is usually transient, myocardial infarction and life-threatening arrhythmias can occur in 25% of cases...
2013: Case Reports in Cardiology
Ghassan Nakad, Hamid Bayeh
We report the case of a 53-years-old patient, known to have coronary artery disease, presenting with typical angina at rest with normal ECG and laboratory findings. His angina is relieved by sublingual nitroglycerin. He had undergone a cardiac catheterisation two weeks prior to his presentation for the same complaints. It showed nonsignificant coronary lesions. Another catheterisation was performed during his current admission. He developed coronary spasm during the procedure, still with no ECG changes. The spasm was reversed by administration of 2 mg of intracoronary isosorbide dinitrate...
2013: Case Reports in Cardiology
Matthew S Cain, William Prinzmetal, Arthur P Shimamura, Ayelet N Landau
Action video game players (VGPs) have demonstrated a number of attentional advantages over non-players. Here, we propose that many of those benefits might be underpinned by improved control over exogenous (i.e., stimulus-driven) attention. To test this we used an anti-cueing task, in which a sudden-onset cue indicated that the target would likely appear in a separate location on the opposite side of the fixation point. When the time between the cue onset and the target onset was short (40 ms), non-players (nVGPs) showed a typical exogenous attention effect...
2014: Frontiers in Psychology
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