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innovation of light

Peter Grindrod
We discuss the governing forces for analytics, especially concerning citizens' behaviours and their transactions, that depend on which of three spheres of operation an institution is in (corporate, public sector/government and academic). We argue that aspirations and missions also differ by sphere even as digital spaces have drawn these spheres ever closer together. We propose that citizens' expectations and implicit permissions for any exploitation of their data require the perception of a fair balance of benefits, which should be transparent (accessible to citizens) and justifiable...
December 28, 2016: Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences
Brigitte Poulin, Gaëtan Lefebvre, Camille Muranyi-Kovacs, Samuel Hilaire
We tested the use of mosquito traps as an alternative to spraying insecticide in Camargue (France) following the significant impacts observed on the non-target fauna through Bti persistence and trophic perturbations. In a village of 600 inhabitants, 16 Techno Bam traps emitting CO₂ and using octenol lures were set from April to November 2016. Trap performance was estimated at 70% overall based on mosquitoes landing on human bait in areas with and without traps. The reduction of Ochlerotatus caspius and Oc...
March 18, 2017: International Journal of Environmental Research and Public Health
Jiang Liu, Dustin Yuan Chen, Xinning Luan, Kwing Tong, Fangchao Zhao, Chao Liu, Qibing Pei, Huaping Li
We report vertical, electrolyte-gated, red, green and blue phosphorescent small molecule organic light emitting diodes (OLED), in which light emission was modified by tuning the electron injection via electrochemical doping of the electron injection layer 4,4-bis(N-carbazolyl)-1,1-biphenyl (CBP) under the assistance of a polymer electrolyte. These devices comprise an electrolyte capacitor on top of a conventional OLED, with the interfacial contact between the electrolyte and electron injection layer CBP of OLEDs achieved through a porous cathode...
March 23, 2017: ACS Applied Materials & Interfaces
Julie Russier, Laura Oudjedi, Martin Piponnier, Cyrill Bussy, Maurizio Prato, Kostas Kostarelos, Brahim Lounis, Alberto Bianco, Laurent Cognet
Assessment of biodegradability of carbon nanotubes (CNTs) is a critically important aspect that needs to be solved before their translation into new biomedical tools. CNT biodegradation has been shown both in vitro and in vivo, but we are limited by the number of analytical techniques that can be used to follow the entire process. Photothermal imaging (PhI) is an innovative technique that enables the quantitative detection of nanometer-sized absorptive objects. In this study, we demonstrate that PhI allows the observation of the degradation process of functionalized multi-walled carbon nanotubes (MWCNTs) following their internalization by primary glial cells...
March 22, 2017: Nanoscale
Michela Lupia, Ugo Cavallaro
The cancer stem cell (CSC) model proposes that tumor development and progression are fueled and sustained by undifferentiated cancer cells, endowed with self-renewal and tumor-initiating capacity. Ovarian carcinoma, based on its biological features and clinical evolution, appears as a prototypical example of CSC-driven disease. Indeed, ovarian cancer stem cells (OCSC) would account not only for the primary tumor growth, the peritoneal spread and the relapse, but also for the development of chemoresistance, thus having profound implication for the treatment of this deadly disease...
March 20, 2017: Molecular Cancer
Nicolas Hanauer, Pierre Luc Latreille, Xavier Banquy
In this study, we report the directed assembly of hydrogel blocks mediated by electrostatic interactions. We compared two different assembly mechanisms, one mediated by microgel particles and another mediated by direct interaction between oppositely charged blocks. The system consisted in hydrogel blocks made of an interpenetrated network of (hydroxyethyl)methacrylate-poly(ethyleneglycol)dimethacrylate (HEMA-PEGDMA) and either positively charged polyethyleneimine (PEI) or negatively charged hyaluronic acid (HA)...
March 20, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
Ananda S Bhattacharjee, Sha Wu, Christopher E Lawson, Mike S M Jetten, Vikram Kapoor, Jorge W Santo Domingo, Katherine D McMahon, Daniel R Noguera, Ramesh Goel
Anaerobic-ammonia-oxidation (anammox) combined with partial-nitritation (PN) is an innovative treatment process for energy-efficient nitrogen removal from wastewater. In this study, we used genome-based metagenomics to investigate the overall community structure and anammox species enriched in suspended growth (SGR) and attached growth packed bed (AGR) anammox reactors after 220 days of operation. Both reactors removed more than 85% of the total inorganic nitrogen. Metagenomic binning and phylogenetic analysis revealed that two anammox population genomes, affiliated with the genus 'Candidatus Brocadia', were differentially abundant between the SGR and AGR...
March 17, 2017: Environmental Science & Technology
Silvia Regina Garcia Olivan, Alessandro Melo Deana, Marcelo Mendes Pinto, Ravana Angelini Sfalcin, Kristianne Porta Santos Fernandes, Raquel Agnelli Mesquita-Ferrari, Renato Araujo Prates, Sandra Kalil Bussadori
BACKGROUND: In this study is presented the correlation between laser speckle images and detection of incipient caries lesions by changing the microstructure of the surface of tooth enamel. METHODS: We used 30 healthy deciduous molar teeth collected from the Biobank Human Teeth, Faculty of Dentistry, University of São Paulo who had carious lesions induced by the pH cycling method. The samples were evaluated for the diagnosis of caries by two METHODS: ICDAS and speckle pattern of coherent light scattering after 5, 10 and 15days and the results were statistically analyzed using α=0...
March 11, 2017: Photodiagnosis and Photodynamic Therapy
Melpomeni Fani, Petra Kolenc Peitl, Irina Velikyan
Nuclear medicine plays a pivotal role in the management of patients affected by neuroendocrine neoplasms (NENs). Radiolabeled somatostatin receptor analogs are by far the most advanced radiopharmaceuticals for diagnosis and therapy (radiotheranostics) of NENs. Their clinical success emerged receptor-targeted radiolabeled peptides as an important class of radiopharmaceuticals and it paved the way for the investigation of other radioligand-receptor systems. Besides the somatostatin receptors (sstr), other receptors have also been linked to NENs and quite a number of potential radiolabeled peptides have been derived from them...
March 15, 2017: Pharmaceuticals
Si Wu, James Blinco, Christopher Barner-Kowollik
The majority of photoreactions reported in the literature rely on wavelength within the UV and - to a lesser extent - visible regime for activation, either by directly triggering the reaction or by photocatalysis. However, photoreactions induced by near-infrared (NIR) light are highly attractive for biomedical applications as NIR light can penetrate deeper into tissue and causes less damage to photosensitive biological systems. Recently, upconverting nanoparticles (UCNPs) have been employed by us and others to assist NIR photo-induced reactions...
March 15, 2017: Chemistry: a European Journal
Tokiyoshi Matsuda, Kenta Umeda, Yuta Kato, Daiki Nishimoto, Mamoru Furuta, Mutsumi Kimura
Oxide semiconductors have been investigated as channel layers for thin film transistors (TFTs) which enable next-generation devices such as high-resolution liquid crystal displays (LCDs), organic light emitting diode (OLED) displays, flexible electronics, and innovative devices. Here, high-performance and stable Ga-Sn-O (GTO) TFTs were demonstrated for the first time without the use of rare metals such as In. The GTO thin films were deposited using radiofrequency (RF) magnetron sputtering. A high field effect mobility of 25...
March 14, 2017: Scientific Reports
Igor V Korobeinikov, Natalia V Morozova, Vladimir V Shchennikov, Sergey V Ovsyannikov
Controlled tuning the electrical, optical, magnetic, mechanical and other characteristics of the leading semiconducting materials is one of the primary technological challenges. Here, we demonstrate that the electronic transport properties of conventional single-crystalline wafers of germanium may be dramatically tuned by application of moderate pressures. We investigated the thermoelectric power (Seebeck coefficient) of p- and n-type germanium under high pressure to 20 GPa. We established that an applied pressure of several GPa drastically shifts the electrical conduction to p-type...
March 14, 2017: Scientific Reports
Han Sun, Bin Liu, Xue Lu, Ka-Wing Cheng, Feng Chen
An innovative staged cultivation (SC) method was proposed to overcome the limiting factors associated with the growth of Haematococcus pluvialis in the green growth phase. This strategy led to a 1.16-fold increase in biomass concentration. Light wavelength, nutrient concentration and extracellular metabolite were identified to be key limiting factors when cells of H. pluvialis were in the low, medium, and high cell density sub-phase, respectively. A mix of red and white light (2:1) was demonstrated for the first time to accelerate cell growth in the low cell density sub-phase...
March 4, 2017: Bioresource Technology
Meng-Chi Li, Ying-Feng Chang, Huai-Yi Wang, Yu-Xen Lin, Chien-Cheng Kuo, Ja-An Annie Ho, Cheng-Chung Lee, Li-Chen Su
White-light scanning interferometry (WLSI) is often used to study the surface profiles and properties of thin films because the strength of the technique lies in its ability to provide fast and high resolution measurements. An innovative attempt is made in this paper to apply WLSI as a time-domain spectroscopic system for localized surface plasmon resonance (LSPR) sensing. A WLSI-based spectrometer is constructed with a breadboard of WLSI in combination with a spectral centroid algorithm for noise reduction and performance improvement...
March 10, 2017: Scientific Reports
José Bento Pereira Lima, Allan Kardec Ribeiro Galardo, Leonardo Soares Bastos, Arthur Weiss da Silva Lima, Maria Goreti Rosa-Freitas
Here, we describe the development of the MosqTent, an innovative double-chamber mosquito trap in which a human being attracts mosquitoes while is protected from being bitten within the inner chamber of the trap, while mosquitoes are lured to enter an outer chamber where they are trapped. The MosqTent previously collected an average of 3,000 anophelines/man-hour compared to 240 anophelines/man-hour for the human landing catch (HLC), thereby providing high numbers of human host-seeking mosquitoes while protecting the collector from mosquito bites...
March 2017: PLoS Neglected Tropical Diseases
Steven M Flipse, Steven Puylaert
Following societal and policy pressures for responsible innovation, innovators are more and more expected to consider the broader socio-ethical context of their work, and more importantly, to integrate such considerations into their daily practices. This may require the involvement of 'outsiders' in innovation trajectories, including e.g. societal and governmental actors. However, methods on how to functionally organize such integration in light of responsible innovation have only recently started to emerge...
March 8, 2017: Science and Engineering Ethics
Youbin Chen, Jiankun Xu, Zhonglian Huang, Menglei Yu, Yuantao Zhang, Hongjiang Chen, Zebin Ma, Haojie Liao, Jun Hu
Although great efforts are being made using growth factors and gene therapy, the repair of bone defects remains a major challenge in modern medicine that has resulted in an increased burden on both healthcare and the economy. Emerging tissue engineering techniques that use of combination of biodegradable poly-lactic-co-glycolic acid (PLGA) and mesenchymal stem cells have shed light on improving bone defect healing; however, additional growth factors are also required with these methods. Therefore, the development of novel and cost-effective approaches is of great importance...
March 8, 2017: Scientific Reports
Shunli Liu, Kewen Li, Fang Yao, Liqun Xu, Guodong Fu
Nacre-like hybrid films based on N-succinyl chitosan (NSC), sodium alginate (SA) and lanthanide ions were fabricated via coordination interactions. In this work, the binary building blocks (NSC and SA) were self-assembled into aligned hydrogel films by coordination with lanthanide ions, and hierarchical NSC-SA hybrid films were obtained upon drying. Two species of lanthanide ions (Gd(3+) and Yb(3+)) were used to fabricate the hierarchical NSC-SA hybrid films. The as-prepared NSC-SA hybrid films exhibit high tensile strength and stability...
May 1, 2017: Carbohydrate Polymers
Siwen Li, Sisi Cui, Deyan Yin, Qiuyun Zhu, Yuxiang Ma, Zhiyu Qian, Yueqing Gu
Photodynamic therapy (PDT) has recently been proposed as an innovative approach to combat multi-drug resistant (MDR) bacteria. To improve the penetration depth of current PDT, a core-shell upconversion nanoparticle (UCNP) based PDT system, composed of a cationic N-octyl chitosan (OC) coated UCNP loaded with the photosensitizer zinc phthalocyanine (OC-UCNP-ZnPc), was constructed to enhance the antibacterial efficacy against MDR bacteria in deep tissue. The core-shell UCNPs displayed a higher upconversion fluorescence efficiency compared to the inner UCNP core...
March 6, 2017: Nanoscale
Masumi Eto, Toshio Kitazawa
A hallmark of smooth muscle cells is their ability to adapt their functions to meet temporal and chronic fluctuations in their demands. These functions include force development and growth. Understanding the mechanisms underlying the functional plasticity of smooth muscles, the major constituent of organ walls, is fundamental to elucidating pathophysiological rationales of failures of organ functions. Also, the knowledge is expected to facilitate devising innovative strategies that more precisely monitor and normalize organ functions by targeting individual smooth muscles...
2017: Journal of Smooth Muscle Research, Nihon Heikatsukin Gakkai Kikanshi
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