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https://www.readbyqxmd.com/read/29781900/concomitant-use-of-1-550-nm-nonablative-fractional-laser-with-low-dose-isotretinoin-for-the-treatment-of-acne-vulgaris-in-asian-patients-a-randomized-split-face-controlled-study
#1
Jun Xia, Guanglei Hu, Die Hu, Songmei Geng, Weihui Zeng
BACKGROUND: Nonablative fractional laser (NAFL) has been shown to improve the appearance of inflammatory acne and acne scars. Isotretinoin is effective for the treatment of moderate-to-severe cases of recalcitrant acne. However, the recommended dose of isotretinoin can have profound effects. OBJECTIVE: To investigate the clinical efficacy and safety of performing NAFL treatment in patients with moderate-to-severe acne vulgaris under treatment with low-dose oral isotretinoin...
May 16, 2018: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/29779037/expression-of-cancer-stem-cell-markers-cd44-aldh1-and-p75ntr-in-actinic-cheilitis-and-lip-cancer
#2
Marcos Custódio, Cibele Pelissari, Thalita Santana, Marília Trierveiler
PURPOSE: The aim of this work was to evaluate the expression of the cancer stem cell (CSC) markers CD44, ALDH1 and p75NTR in the ultraviolet-induced lesions actinic cheilitis (AC) and lip squamous cell carcinoma (LSCC), and to correlate it with p53 expression. METHODS: Immunohistochemistry was performed in 4 cases of normal lip (NL), 43 of AC and 20 of LSCC. RESULTS: All cases were positive for CD44, showing a membranous staining without differences between the groups...
May 19, 2018: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29766816/a-systematic-review-of-the-literature-of-the-three-related-disease-entities-cheilitis-granulomatosa-orofacial-granulomatosis-and-melkersson-rosenthal-syndrome
#3
Goetz Wehl, Markus Rauchenzauner
BACKGROUND AND OBJECTIVE: Melkersson Rosenthal syndrome (MRS) is a rare disorder of unknown etiology and comprises the triad: orofacial edema, recurrent facial paralysis and lingua plicata. In the current literature confusing heterogeneity exists, mixing together the historically grown terms cheilitis granulomatosa or granulomatous cheilitis, Melkersson Rosenthal syndrome and the umbrella term orofacial granulomatosis (OFG). METHODS: We provide a systematic review comprising all three disease entities of orofacial granulomatosis using the computerized database "Pubmed Medline" entering the key words "orofacial granulomatosis" (141 references), "Melkersson-Rosenthal syndrome" (207 references), "granulomatous cheilitis" or "cheilitis granulomatosa" (102 references) back to 1956...
May 14, 2018: Current Pediatric Reviews
https://www.readbyqxmd.com/read/29761881/expression-of-stem-cell-markers-nanog-and-nestin-in-lip-squamous-cell-carcinoma-and-actinic-cheilitis
#4
Fernanda M Scotti, Verônica C Mitt, Daniella S C Vieira, Michelle T Biz, Renata G Castro, Filipe Modolo
Cancer stem cells ( CSC ) proteins have been observed in several lesions and are associated with tumor beginning, evolution, and resistance to treatment. OBJECTIVES: to investigate the presence of NANOG, NESTIN, and β-tubulin in lip squamous cell carcinoma (LSCC), actinic cheilitis (AC), and normal epithelium (NE). MATERIALS AND METHODS: thirty cases of LSCC, thirty cases of AC (both analyzed according to the WHO classification and AC according to the binary classification), and twenty cases of NE were submitted to an immunohistochemical study...
May 15, 2018: Oral Diseases
https://www.readbyqxmd.com/read/29752702/daylight-photodynamic-therapy-for-actinic-keratoses
#5
REVIEW
Colin A Morton, Lasse R Braathen
Topical photodynamic therapy (PDT) using daylight is effective in the treatment of actinic keratoses (AKs), offering the potential for treatment of large fields such as full face and balding scalp, but with minimal therapy-associated pain. Comparison with conventional PDT indicates similar efficacy for thin and moderate-thickness AKs, but with significantly less discomfort/pain, driving a patient preference for daylight-mediated PDT (DL-PDT) compared with conventional PDT using high-intensity office/hospital-based light sources...
May 11, 2018: American Journal of Clinical Dermatology
https://www.readbyqxmd.com/read/29749619/allergic-contact-cheilitis-in-an-adolescent-to-ricinus-communis-seed-oil-castor-oil-in-a-lip-balm
#6
Alejandro Sánchez-Herrero, Ana Mateos-Mayo, Enrique Rodríguez-Lomba, Irene Molina-López, Minia Campos-Domínguez, Ricardo Suárez Fernández
No abstract text is available yet for this article.
May 11, 2018: Contact Dermatitis
https://www.readbyqxmd.com/read/29744227/cheilitis-glandularis-of-both-lips-successful-treatment-with-a-combination-of-an-intralesional-steroid-injection-and-tacrolimus-ointment
#7
Norberto Sugaya, Dante Migliari
Cheilitis glandularis (CG) is an inflammatory condition of unknown cause that predominantly affects the minor salivary glands of the lips. Although a diagnosis of CG is not difficult, its treatment is a challenge. This article highlights the clinical presentation of the disease together with a case of successful management of this disease using a combination of a steroid injection followed by a topical immunosuppressor.
2018: Case Reports in Dentistry
https://www.readbyqxmd.com/read/29740875/evaluation-of-epithelial-dysplasia-adjacent-to-lip-squamous-cell-carcinoma-indicates-that-the-degree-of-dysplasia-is-not-associated-to-the-occurrence-of-invasive-carcinoma-in-this-site
#8
Gabriela Nagata, Thalita Santana, Aline Queiroz, Renata Helena Caramez, Marília Trierveiler
BACKGROUND: We analyzed the different grades of dysplasia in the epithelium adjacent to lip squamous cell carcinoma (LSCC), as a parallel to actinic cheilitis (AC) that suffered malignant transformation. METHODS: Forty samples of epithelium adjacent to LSCC were histologically graded according to the World Health Organization (WHO) and the binary systems. The expression of mutated p53 was evaluated through immunohistochemistry. RESULTS: According to WHO system, 37...
May 8, 2018: Journal of Cutaneous Pathology
https://www.readbyqxmd.com/read/29738071/prevalence-of-oral-potentially-malignant-disorders-a-systematic-review-and-meta-analysis
#9
REVIEW
Fernanda Weber Mello, Andressa Fernanda Paza Miguel, Kamile Leonardi Dutra, André Luís Porporatti, Saman Warnakulasuriya, Eliete Neves Silva Guerra, Elena Riet Correa Rivero
Oral potentially malignant disorders (OPMD) are chronic conditions, which have a higher risk of transformation to oral squamous cell carcinoma. The aim of this systematic review and meta-analysis was to answer the question: "What is the prevalence of oral potentially malignant disorders among adults?". Studies reporting the prevalence of these conditions (leukoplakia, erythroplakia, oral submucous fibrosis, and actinic cheilitis) were selected, only studies in which a clinical assessment and histopathological confirmation were performed were included...
May 8, 2018: Journal of Oral Pathology & Medicine
https://www.readbyqxmd.com/read/29736657/association-between-oral-mucosal-lesions-and-crack-and-cocaine-addiction-in-men-a-cross-sectional-study
#10
Patricia Ramos Cury, Nara Santos Araujo, Maria das Graças Alonso Oliveira, Jean Nunes Dos Santos
The aim of this cross-sectional study was to evaluate the prevalence of oral mucosal lesions (OMLs) and their association with crack/cocaine addiction in men. Clinical oral examination was performed in 161 adult male patients at the School of Dentistry of the Federal University of Bahia, Brazil. Crack/cocaine addiction was determined from the medical records, and all drug-addicted individuals used both crack and cocaine. All participants (40 crack/cocaine-addicted men and 121 non-addicted men) underwent a systematic evaluation of the lips, labial mucosa, commissures, buccal mucosa and sulcus, gingiva and alveolar ridge, tongue, floor of the mouth, and soft and hard palate by a single examiner...
May 8, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29733533/hyaluronic-acid-dermal-fillers-in-the-management-of-recurrent-angular-cheilitis-a-case-report
#11
Alejandro Ismael Lorenzo-Pouso, Abel García-García, Mario Pérez-Sayáns
OBJECTIVE: To report conservative treatment based on the use of dermal fillers for a case of recurrent angular cheilitis. CASE REPORT: An 80-year-old patient with a history of recurrent angular cheilitis that was not resolved with a conventional approach sought treatment. Complete remission of the pathology was achieved with the injection of hyaluronic acid fillers. CONCLUSION: This case illustrates the potential of nonsurgical facial aesthetics (NSFA) for treating this common pathology among elderly people...
June 2018: Gerodontology
https://www.readbyqxmd.com/read/29728540/evaluation-of-cellular-proliferative-activity-in-patients-with-actinic-cheilitis-through-silver-stained-nucleolar-organizer-region-method
#12
Samela Martins, Bernardo Zoehler, Carmen S Busin, Silas Aj de Freitas Filho, Luiz R Paranhos, Maria Ss Linden, Marcos E de Bittencourt, Joao P de Carli
Introduction: Actinic cheilitis (AC) is a lesion potentially malignant that affects the lips after prolonged exposure to solar ultraviolet (UV) radiation. The present study aimed to assess and describe the proliferative cell activity, using silver-stained nucleolar organizer region (AgNOR) quantification proteins, and to investigate the potential associations between AgNORs and the clinical aspects of AC lesions. Materials and methods: Cases diagnosed with AC were selected and reviewed from Center of Histopathological Diagnosis of the Institute of Biological Sciences, Passo Fundo University, Brazil...
April 1, 2018: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/29725529/non-invasive-imaging-of-actinic-cheilitis-and-squamous-cell-carcinoma-of-the-lip
#13
Mihai Lupu, Ana Caruntu, Constantin Caruntu, Daniel Boda, Liliana Moraru, Vlad Voiculescu, Alexandra Bastian
An early diagnosis is of overwhelming importance for the management and prognosis of mucocutaneous cancer. Actinic cheilitis (AC), defined by the clonal expansion of genomically unstable keratinocytes, is the most common potentially malignant lesion affecting the lips. Squamous cell carcinoma (SCC) is the most frequent oral malignancy, and there is strong evidence that the majority of the SCCs of the lip originate from AC. There is considerable difficulty in discerning between dysplasia and invasive carcinomas solely on a clinical basis...
May 2018: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/29724848/draft-genome-sequence-of-the-first-documented-clinical-siccibacter-turicensis-isolate-in-austria
#14
Sarah Lepuschitz, Shiva Pekard-Amenitsch, Renée Haunold, Simone Schill, Agnes Schriebl, Robert Mach, Franz Allerberger, Werner Ruppitsch, Stephen J Forsythe
The nonpathogenic species Siccibacter turicensis is closely related to members of the food-associated pathogenic genus Cronobacter and has been detected in fruit powders, formula, spices, and herbs. Here, we report on the first clinical isolate of S. turicensis , recovered from the labial angle of a patient with angular cheilitis.
May 3, 2018: Genome Announcements
https://www.readbyqxmd.com/read/29699903/evaluation-of-specific-modified-histones-in-lip-carcinogenesis
#15
Silas Antonio Juvencio de Freitas Filho, João Paulo Silva Servato, Rodrigo Tavares de Sá, Carla Silva Siqueira, Paulo Rogério de Faria, Adriano Mota Loyola, Sérgio Vitorino Cardoso
OBJECTIVE: Histones regulate chromatin density and therefore influence gene expression and cellular proliferation. These properties are modified by methylation, acetylation and phosphorylation of histones. The aim of this study was to investigate the variation of specific modified histones in actinic cheilitis (AC) and squamous cell carcinoma of the lip (SCCL). METHODS: Samples of non-neoplastic tissue of the lip (NNTL, n = 9), AC (n = 33), and SCCL (n = 27) were submitted to immunohistochemistry to detect the modified histones H3K36me3, H3K9ac, H4K12ac, and H3S10 ph...
April 22, 2018: Pathology, Research and Practice
https://www.readbyqxmd.com/read/29687567/dermoscopy-and-reflectance-confocal-microscopy-for-monitoring-the-treatment-of-actinic-cheilitis-with-ingenol-mebutate-gel-report-of-three-cases
#16
E Benati, R Pampena, C Bombonato, S Borsari, M Lombardi, C Longo
Actinic cheilitis (AC) can precede the development of squamous cell carcinoma (SCC) of the lip, a location with higher risk of invasiveness and metastasis. Herein, we reported the use of ingenol mebutate (IngMeb) 0.015% gel on three consecutive days to treat three patients suffering from AC. All the three patients achieved complete clearance of AC with rapid clinical effect, favorable safety profile, good patient's compliance related to short time of applications, and few local skin reactions. So IngMeb is an attractive new therapy for AC...
April 24, 2018: Dermatologic Therapy
https://www.readbyqxmd.com/read/29676362/expression-of-e-cadherin-syndecan-1-ki-67-and-maintenance-minichromosome-3-in-tissue-lesions-of-actinic-prurigo-obtained-by-incisional-biopsy
#17
Alexandra Mancheno-Valencia, Ronell Eduardo Bologna-Molina, Sonia Toussaint-Caire, María Elisa Vega-Memije, Juan Carlos Cuevas-González
Actinic prurigo (AP) is an idiopathic photodermatosis; the initial manifestations usually occur during the first decades of life but can appear at any age. Cases are usually diagnosed late once the lesions have exacerbated; due to the extensive involvement of the vermilion border and the etiology, it has been confused with and related to a potentially malignant process. Syndecan-1 and E-cadherin were positive in the epidermis, with moderate-to-intense staining in 100% of samples. Ki67 and MCM3 were expressed in the lower third of the epidermis and showed greater immunolabeling in samples that contained lymphoid follicles (Ki 67: epidermis [17...
April 2018: Indian Journal of Pathology & Microbiology
https://www.readbyqxmd.com/read/29559836/orofacial-manifestations-and-temporomandibular-disorders-of-sj%C3%A3-gren-syndrome-an-observational-study
#18
Vito Crincoli, Mariasevera Di Comite, Mariateresa Guerrieri, Rossana Patricia Rotolo, Luisa Limongelli, Angela Tempesta, Florenzo Iannone, Angela Rinaldi, Giovanni Lapadula, Gianfranco Favia
AIMS : Sjӧgren Syndrome is a disorder involving oral tissues, with xerostomia, dysgeusia, dysphagia, tooth decay, gingivitis, angular cheilitis and glossitis. Temporomandibular disorders are a generic term referred to clinical conditions involving the jaw muscles and temporomandibular joint. The aim of this study was to investigate the prevalence of oral manifestations and temporomandibular disorders (TMD) in Sjӧgren Syndrome (SS) patients compared with healthy people. METHODS : The study group included 72 SS patients (2 men, 70 women) diagnosed according to the American-European Consensus Group (AECG) Criteria...
2018: International Journal of Medical Sciences
https://www.readbyqxmd.com/read/29552401/erratum-time-resolved-fluorescence-spectroscopy-for-clinical-diagnosis-of-actinic-cheilitis-erratum
#19
Alessandro Cosci, Marcelo Saito Nogueira, Sebastião Prataviera, Ademar Takahama, Rebeca de Souza Azevedo, Cristina Kurachi
[This corrects the article on p. 4210 in vol. 7, PMID: 27867726.].
February 1, 2018: Biomedical Optics Express
https://www.readbyqxmd.com/read/29551370/treating-isotretinoin-associated-cheilitis-with-hydrocortisone-containing-lip-balm
#20
Brett C Neill, Christopher D Willis, John A Neill, Cody Hanson, Anand Rajpara, Daniel J Aires
No abstract text is available yet for this article.
March 15, 2018: Journal of the American Academy of Dermatology
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