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April 15, 2017: Veterinary Record
Ashley G Boyle, Darko Stefanovski, Shelley C Rankin
BACKGROUND: Streptococcus equi subsp equi (S. equi) is the cause of "equine strangles" which is a highly infectious upper respiratory disease. Detection of S. equi is influenced by site of specimen collection, method of sampling, and type of diagnostic test that is performed. We hypothesized i) that a loop-mediated isothermal amplification (LAMP) assay that targets the S. equi-specific eqbE gene would be more sensitive than a realtime PCR assay that targets the S. equi-specific seeI gene and ii) that LAMP of specimens obtained by guttural pouch lavage (GPL) would be more sensitive than LAMP of nasopharyngeal specimens to identify S...
March 23, 2017: BMC Veterinary Research
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March 18, 2017: Veterinary Record
R Paillot, M R Lopez-Alvarez, J R Newton, A S Waller
No abstract text is available yet for this article.
March 2017: Equine Veterinary Journal
Miriam Strangl, Tanja Fell, Martin Schlummer, Andreas Maeurer, Andrea Buettner
The increasing world population with their growing consumption of goods escalates the issue of sustainability concepts with increasing demands in recycling technologies. Recovery of post-consumer packaging waste is a major topic in this respect. However, contamination with odorous constituents currently curtails the production of recycling products that meet the high expectations of both consumers and industry. To guarantee odor-free recyclates, the main prerequisite is to characterize the molecular composition of the causative odorants in post-consumer plastic packaging waste...
January 30, 2017: Journal of Separation Science
Xue-Mei Wu, Xu-Dong Zhang, Li-Bing Yun, Min Liu, Xu-Fu Yi
Smothering and manual strangulation are not uncommon in domestic violence against women; however, no report on the combination of mechanical asphyxia and intracranial vascular malformations has been previously published. We report a middle-aged woman who was smothered and manually strangled by her husband and subsequently died from subarachnoid hemorrhage due to ruptured intracranial vascular malformations, rather than direct mechanical asphyxiation. Smothering and manual strangulation are considered provocative conditions for rupture and contributory causes of death...
March 2017: American Journal of Forensic Medicine and Pathology
Zachary A McDargh, Pablo Vázquez-Montejo, Jemal Guven, Markus Deserno
Any cellular fission process is completed when the neck connecting almost-separate membrane compartments is severed. This crucial step is somehow accomplished by proteins from the dynamin family, which polymerize into helical spirals around such necks. Much research has been devoted to elucidating the specifics of that somehow, but despite no shortage of ideas, the question is not settled. Pictorially obvious notions of strangling or pushing are difficult to render in mechanically precise terms. Moreover, because dynamin is a GTPase, it is tempting to speculate that it has a motor activity that assists the necessary severing action, but again the underlying mechanics is not obvious...
December 6, 2016: Biophysical Journal
Gleidy Vannesa E Rojas, Hilton Ricz, Vitor Tumas, Guilherme R Rodrigues, Patrícia Toscano, Lílian Aguiar-Ricz
OBJECTIVE: The study aimed to compare and correlate perceptual-auditory analysis of vocal parameters and self-perception in individuals with adductor spasmodic dysphonia before and after the application of botulinum toxin. STUDY DESIGN: This is a prospective cohort study. METHODS: Sixteen individuals with a diagnosis of adductor spasmodic dysphonia were submitted to the application of botulinum toxin in the thyroarytenoid muscle, to the recording of a voice signal, and to the Voice Handicap Index (VHI) questionnaire before the application and at two time points after application...
November 17, 2016: Journal of Voice: Official Journal of the Voice Foundation
S Tirosh-Levy, S E Blum, K F Steward, A S Waller, A Steinman
The purpose of this cross-sectional study was to determine the seroprevalence of Streptococcus equi in Israel, to monitor seropositive horses over time and to identify archived strains that were recovered from Israeli horses. A serological survey of 200 healthy horses on 20 farms throughout Israel was performed to detect recent exposure to S equi antigens A and C via indirect ELISA. Seroprevalence was 9.5 per cent (19/200) and positive horses were found in 30 per cent (6/20) of the farms. Sixteen horses that returned a positive serology result were retested three and six months later...
2016: Veterinary Record Open
Ahmed N F Neamat-Allah, Hend M El Damaty
AIM: Respiratory tract infections are considered the major problem of equine worldwide. Strangles is an infectious and highly contagious respiratory bacterial disease of equine caused by Streptococcus equi. This study is aimed to evaluate some clinical and epidemiological investigation associated with strangles and to study the hematological and biochemical changes in 20 Arabian horse naturally infected with S. equi during the disease and after 10 days from treatment by procaine penicillin with benzathine penicillin...
August 2016: Veterinary World
Nobutoshi Horii, Daisuke Morioka, Kazuya Yamaguchi, Yoshiki Sato, Masaru Miura, Mikiko Tanabe
We describe a case of bowel strangulation caused by massive peritoneal adhesion as a result of effective chemotherapy. A 71-year-old man, who had obstructive descending colon cancer with massive peritoneal metastases and, therefore, received palliative surgery consisting of diverting colostomy and sampling of peritoneal nodules, developed bowel strangulation on day 4 of the 2nd course of chemotherapy, including irinotecan, l-leucovorin, and 5-fluorouracil. Emergent celiotomy showed a massive intraperitoneal adhesion formed around several intestinal loops, which were not observed at the prior surgery...
October 2016: Clinical Journal of Gastroenterology
Margaret A Greven, Darius M Moshfeghi
PURPOSE: To describe a patient with central retinal artery occlusion following an episode of mechanical strangulation. METHODS: A retrospective case report. An 83-year-old man presented with acute vision loss in his right eye after a strangling episode. Multimodal clinical imaging was performed. RESULTS: Visual acuity in the affected right eye was no light perception. Examination revealed optic nerve edema and optic nerve pallor and also severe vascular attenuation and a cherry-red spot in the macula...
June 22, 2016: Retinal Cases & Brief Reports
Julia L Livengood, Saraswathi Lanka, Carol Maddox, Deepanker Tewari
Streptococcus equi subspecies equi (S. equi), the causative agent of strangles, is an important equine pathogen. Strangles is a highly contagious disease and a commercial modified live vaccine (MLV) is used for protection, which although effective, may also result in clinical signs of the disease. A rapid means to differentiate between the MLV and wild-type infection is crucial for quarantine release and limiting the disease spread. This study describes the use of a pyrosequencing assay targeting a single nucleotide deletion upstream of the SzPSe gene to distinguish between the wild-type and vaccine strains...
July 25, 2016: Vaccine
Manoj Bhausaheb Parchake, Vikas Kumre, Rajesh V Kachare
Strangulation is generally considered as homicidal death and in accidental strangulation circumstantial evidence alone can point toward the accidental nature of incidence. In present case, a 71-year-old woman, wearing a saree (garment worn by traditional women in India) working in agricultural field, got entangled in the crop thrasher machine and got strangled. Immediately, she was taken to the nearest hospital, where she survived for 6 to 8 hours and then died. The autopsy reveals cross ribbon-shaped ligature mark on neck and anterior chest along with 1 puncture wound at the right lateral aspect of the neck...
September 2016: American Journal of Forensic Medicine and Pathology
Michael Armstrong, Gael B Strack
IMPORTANCE: Strangulation accounts for 10% of violent deaths in the United States and 15% to 20% of deaths associated with domestic violence. However, strangulation deaths represent only a small fraction of nonfatal strangulation assaults, which occur with daily frequency in medium to large US cities. Careful evaluation and documentation of strangulation injuries may identify life-threatening medical conditions, and may facilitate prosecution of strangulation crimes. OBSERVATIONS: The most recent article on strangulation identified in the otolaryngology literature was published in 1989, leaving a generation of head and neck surgeons without current guidance regarding this injury...
September 1, 2016: JAMA Otolaryngology—Head & Neck Surgery
Izabela E Fedyszyn, Annette Erlangsen, Carsten Hjorthøj, Trine Madsen, Merete Nordentoft
OBJECTIVE: Emergency departments are important, albeit underutilized, sites for suicide prevention. Preventive strategies and interventions could benefit from a greater understanding of factors influencing the course of suicide risk after emergency department contact due to attempted suicide. The aim of our study was 2-fold: to identify predictors of repeated suicide attempts and suicide and to investigate the timing of these events. METHODS: Data from Danish nationwide, longitudinal registers were used in this prospective, population-based study of all individuals first presenting to an emergency department after attempted suicide (index attempt) between January 1, 1996, and December 31, 2011 (N = 11,802)...
June 2016: Journal of Clinical Psychiatry
Yeliena Baber, Eleanor Bott
Deaths in an autoerotic setting are usually due to accidental asphyxia, in which the individual accidently hangs or strangles themselves while inducing hypoxia for the purpose of heightened arousal. Death occurs when the level of hypoxia causes the individual to lose consciousness and is thus unable to prevent the neck compression from becoming lethal. In some cases there is an "escape" mechanism incorporated into the set-up which may fail. In rare cases, death is not as an immediate result of the autoerotic activity and is as a result of natural causes, which may or may not be related to the process...
June 2016: Forensic Science, Medicine, and Pathology
Felix J F Herth, Ralf Eberhardt
PURPOSE OF REVIEW: Patients with lung cancer often develop endobronchial disease, endobronchial tumor extension or airway compression. Various nonmalignant diseases can also lead to severe central airway obstruction.Since the early 1980s, technical advances of interventional bronchoscopic techniques have improved symptom-free survival and quality of life for patients with lung cancer. Apart from other techniques, various airway stents have been developed. Although interventional procedures are not definitive therapies, they often relieve the strangling sensation produced by airway occlusion...
May 2016: Current Opinion in Pulmonary Medicine
Felipe Libardoni, Gustavo Machado, Letícia Trevisan Gressler, Ananda Paula Kowalski, Gustavo Nogueira Diehl, Lucila Carboneiro dos Santos, Luis Gustavo Corbellini, Agueda Castagna de Vargas
The aim of this study was to estimate the prevalence of equine strangles and to identify associated risk factors for this disease through a cross-sectional study of nasal swabs. Nasal swabs (n=1010) from healthy equines (absence of nasal discharge, lymphadenopathy and cough) from 341 farms were plated on 5% blood agar; of these horses, 24 were identified as positive for Streptococcus equi through isolation, PCR and DNA sequencing. The estimated prevalence for individual animals was 2.3%, and for herds, it was 5...
February 2016: Research in Veterinary Science
Tetsuji Sanuki, Eiji Yumoto, Yutaka Toya, Yoshihiko Kumai
OBJECTIVE: Adductor spasmodic dysphonia is a rare voice disorder characterized by strained and strangled voice quality with intermittent phonatory breaks and adductory vocal fold spasms. Type II thyroplasty differs from previous treatments in that this surgery does not involve any surgical intervention into the laryngeal muscle, nerve or vocal folds. Type II thyroplasty intervenes in the thyroid cartilage, which is unrelated to the lesion. This procedure, conducted with the aim of achieving lateralization of the vocal folds, requires utmost surgical caution due to the extreme delicacy of the surgical site, critically sensitive adjustment, and difficult procedures to maintain the incised cartilages at a correct position...
October 2016: Auris, Nasus, Larynx
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