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https://www.readbyqxmd.com/read/28881337/surgical-management-of-a-de-garengeot-s-hernia-using-a-biologic-mesh-a-case-report-and-review-of-literature
#1
Amandine Klipfel, Aïna Venkatasamy, Caroline Nicolai, Marie-Noëlle Roedlich, Francis Veillon, Cécile Brigand, Serge Rohr, Benoît Romain
INTRODUCTION: A De Garengeot hernia is a rare form of femoral hernia, where the appendix is found in the herniated sac. This feature is important to report, as both the diagnosis and the treatment are quite challenging in this particular condition. PRESENTATION OF CASE: We report the case of a 77-year-old female presenting with a femoral hernia, containing an incarcerated necrotic vermiform appendix (De Garengeot hernia). A laparoscopic appendectomy was performed and the herniated defect was repaired according to Rives technique, using a biological mesh...
August 18, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28749324/investigation-of-the-fim1-putative-pilus-locus-of-streptococcus-equi-subspecies-equi
#2
Karen Frances Steward, Carl Robinson, Duncan J Maskell, Chiara Nenci, Andrew Stephen Waller
The Gram-positive bacterium Streptococcus equi subspecies equi (S. equi) is the causative agent of strangles, among the most frequently diagnosed infectious diseases of horses worldwide. Genome analysis of S. equi strain 4047 (Se4047) identified a putative operon, Fim1, with similarity to the pilus loci of other Gram-positive bacteria. The Fim1 locus was present in all strains of S. equi and its close relative S. equi subspecies zooepidemicus (S. zooepidemicus) that have been studied to date. In this study we provide evidence that the putative structural pilus proteins, SEQ_0936 and CNE, are produced on the cell surface during in vitro growth and in vivo infection...
July 28, 2017: Microbiology
https://www.readbyqxmd.com/read/28721189/strangulated-gallbladder-caused-by-a-tip-of-the-omentum-attached-to-the-abdominal-wall-a-case-report
#3
Atsushi Kohga, Takuya Okumura, Kenji Suzuki, Kiyoshige Yajima, Kimihiro Yamashita, Jun Isogaki, Akihiro Kawabe, Taizo Kimura
Strangulation of the gallbladder associated with the omentum is extremely rare and, to our knowledge, only two cases have been previously reported. The patient was a 91-year-old female who presented to our emergency room with a chief complaint of upper abdominal pain. Computed tomography imaging revealed a gourd-shaped gallbladder with biphasic appearance divided clearly at the body. In the fundus side, the wall of the gallbladder was oedematous and thickened, while the neck side was intact. On the second day after onset, a laparoscopic cholecystectomy was performed...
July 2017: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/28701052/-they-accused-me-of-strangling-her-epilepsy-and-violence-debate-in-croatia-at-the-end-of-the-nineteenth-and-the-beginning-of-the-twentieth-centuries
#4
Martin Kuhar, Stella Fatović-Ferenčić
Nineteenth-century psychiatry shifted its focus to the brain as the seat of mental disorders. With a new understanding of mental disorders arose the need to consult forensic psychiatrists in cases of criminal acts committed by persons with mental illness. This article focuses on three murders committed by 'epileptics' at the end of the nineteenth and the beginning of the twentieth centuries in Croatia. An analysis of these cases will help to situate forensic psychiatry at the turn of the century within the Austro-Hungarian Empire, and reveal the authority that forensic experts wielded in the courts...
July 1, 2017: History of Psychiatry
https://www.readbyqxmd.com/read/28667907/non-alcoholic-fatty-liver-disease-to-struggle-with-the-strangle-oxygen-availability-in-fatty-livers
#5
Sarit Anavi, Zecharia Madar, Oren Tirosh
Nonalcoholic fatty liver diseases (NAFLD) is one of the most common chronic liver disease in Western countries. Oxygen is a central component of the cellular microenvironment, which participate in the regulation of cell survival, differentiation, functions and energy metabolism. Accordingly, sufficient oxygen supply is an important factor for tissue durability, mainly in highly metabolic tissues, such as the liver. Accumulating evidence from the past few decades provides strong support for the existence of interruptions in oxygen availability in fatty livers...
June 22, 2017: Redox Biology
https://www.readbyqxmd.com/read/28636633/playing-with-fire-what-is-influencing-horse-owners-decisions-to-not-vaccinate-their-horses-against-deadly-hendra-virus-infection
#6
Kailiea Arianna Goyen, John David Wright, Alexandra Cunneen, Joerg Henning
Hendra virus is a zoonotic paramyxovirus, which causes severe respiratory and neurological disease in horses and humans. Since 2012, the Hendra virus sub-unit G vaccine has been available for horse vaccination in Australia. Uptake of the vaccine has been limited and spill-over events of Hendra virus infection in horses continue to occur. We conducted an online, questionnaire-based cross-sectional study of 376 horse owners belonging to a variety of different equestrian clubs in Queensland, Australia, to identify risk factors for non-vaccination against Hendra virus...
2017: PloS One
https://www.readbyqxmd.com/read/28634151/speech-and-swallowing-abnormalities-in-adults-with-polg-associated-ataxia-polg-a
#7
Adam P Vogel, Natalie Rommel, Andreas Oettinger, Marius Horger, Patrick Krumm, Eva-Maria Kraus, Ludger Schöls, Matthis Synofzik
BACKGROUND: Mutations in the nuclear-encoded mitochondrial DNA polymerase gamma (POLG) can result in a wide spectrum of neurological deficits. A common presentation is progressive ataxia (POLG-A) which includes impaired speech and swallowing. The nature, severity and impact of these deficits in POLG-A is not known. A comprehensive quantitative and qualitative characterization of dysarthria and dysphagia in this recurrent ataxia disorder will assist in diagnostics, provide insights into the underlying pathology, and establish the foundation for future therapy trials...
June 19, 2017: Mitochondrion
https://www.readbyqxmd.com/read/28569630/a-case-control-study-developing-a-model-for-predicting-risk-factors-for-high-sem-specific-antibody-titers-after-natural-outbreaks-of-streptococcus-equi-subsp-equi-infection-in-horses
#8
Ashley G Boyle, Meagan A Smith, Raymond C Boston, Darko Stefanovski
OBJECTIVE To develop a risk prediction model for factors associated with an SeM-specific antibody titer ≥ 3,200 in horses after naturally occurring outbreaks of Streptococcus equi subsp equi infection and to validate this model. DESIGN Case-control study. ANIMALS 245 horses: 57 horses involved in strangles outbreaks (case horses) and 188 healthy horses (control horses). PROCEDURES Serum samples were obtained from the 57 cases over a 27.5-month period after the start of outbreaks; serum samples were obtained once from the 188 controls...
June 15, 2017: Journal of the American Veterinary Medical Association
https://www.readbyqxmd.com/read/28569133/defining-the-abc-of-gene-essentiality-in-streptococci
#9
Amelia R L Charbonneau, Oliver P Forman, Amy K Cain, Graham Newland, Carl Robinson, Mike Boursnell, Julian Parkhill, James A Leigh, Duncan J Maskell, Andrew S Waller
BACKGROUND: Utilising next generation sequencing to interrogate saturated bacterial mutant libraries provides unprecedented information for the assignment of genome-wide gene essentiality. Exposure of saturated mutant libraries to specific conditions and subsequent sequencing can be exploited to uncover gene essentiality relevant to the condition. Here we present a barcoded transposon directed insertion-site sequencing (TraDIS) system to define an essential gene list for Streptococcus equi subsp...
May 31, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28532794/immunogenicity-of-phospholipase-a2-toxins-and-their-role-in-streptococcus-equi-pathogenicity
#10
M R López-Álvarez, M Salze, A Cenier, C Robinson, R Paillot, A S Waller
Streptococcus equi subsp. equi (S. equi) is the causative agent of strangles, one of the most frequently diagnosed infectious diseases of horses worldwide. Phospholipase A2 toxins (PLA2) cleave phospholipid molecules at position sn-2 contributing to the production of leukotrienes that are important inflammatory mediators. Two homologous phospholipases, SlaA and SlaB are encoded by the S. equi genome suggesting that PLA2 toxins may contribute to its pathogenicity. Here we report the immunogenicity and role of PLA2 toxins during natural and experimental infection of horses with S...
May 2017: Veterinary Microbiology
https://www.readbyqxmd.com/read/28480431/anti-viral-effect-of-herbal-medicine-korean-traditional-cynanchum-paniculatum-bge-kitag-extracts
#11
Woong Kim, Tae-Seok Oh, Youn-Jin Park
BACKGROUND: Pestiviruses in general, and Bovine Viral Diarrhea (BVD) in particular, present several potential targets for directed antiviral therapy. MATERIAL AND METHODS: The antiviral effect of Cynanchum paniculatum (Bge.) Kitag (Dog strangling vine: DS) extract on the bovine viral diarrhea (BVD) virus was tested. First, a cytotoxicity test in MDBK (Madin-Darby bovine kidney) cells was done with all organic extract concentrations. RESULTS: The cytotoxic concentration CC50 for the ethyl acetate (EA) extracts was 18...
2017: African Journal of Traditional, Complementary, and Alternative Medicines: AJTCAM
https://www.readbyqxmd.com/read/28460559/discrimination-of-streptococcus-equi-subsp-equi-and-streptococcus-equi-subsp-zooepidemicus-using-matrix-assisted-laser-desorption-ionization-time-of-flight-mass-spectrometry
#12
Rinosh J Mani, Anil J Thachil, Akhilesh Ramachandran
Accurate and timely identification of infectious etiologies is of great significance in veterinary microbiology, especially for critical diseases such as strangles, a highly contagious disease of horses caused by Streptococcus equi subsp. equi. We evaluated a matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) platform for use in species- and subspecies-level identification of S. equi isolates from horses and compared it with an automated biochemical system. We used 25 clinical isolates each of S...
April 1, 2017: Journal of Veterinary Diagnostic Investigation
https://www.readbyqxmd.com/read/28408510/vet-students-help-regiments-declare-their-horses-to-be-strangles-free
#13
(no author information available yet)
No abstract text is available yet for this article.
April 15, 2017: Veterinary Record
https://www.readbyqxmd.com/read/28335829/comparison-of-nasopharyngeal-and-guttural-pouch-specimens-to-determine-the-optimal-sampling-site-to-detect-streptococcus-equi-subsp-equi-carriers-by-dna-amplification
#14
Ashley G Boyle, Darko Stefanovski, Shelley C Rankin
BACKGROUND: Streptococcus equi subsp equi (S. equi) is the cause of "equine strangles" which is a highly infectious upper respiratory disease. Detection of S. equi is influenced by site of specimen collection, method of sampling, and type of diagnostic test that is performed. We hypothesized i) that a loop-mediated isothermal amplification (LAMP) assay that targets the S. equi-specific eqbE gene would be more sensitive than a realtime PCR assay that targets the S. equi-specific seeI gene and ii) that LAMP of specimens obtained by guttural pouch lavage (GPL) would be more sensitive than LAMP of nasopharyngeal specimens to identify S...
March 23, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28302885/strangles-stamping-out-misconceptions
#15
(no author information available yet)
No abstract text is available yet for this article.
March 18, 2017: Veterinary Record
https://www.readbyqxmd.com/read/28177153/strangles-a-modern-clinical-view-from-the-17th-century
#16
EDITORIAL
R Paillot, M R Lopez-Alvarez, J R Newton, A S Waller
No abstract text is available yet for this article.
March 2017: Equine Veterinary Journal
https://www.readbyqxmd.com/read/28133911/characterization-of-odorous-contaminants-in-post-consumer-plastic-packaging-waste-using-multidimensional-gas-chromatographic-separation-coupled-with-olfactometric-resolution
#17
Miriam Strangl, Tanja Fell, Martin Schlummer, Andreas Maeurer, Andrea Buettner
The increasing world population with their growing consumption of goods escalates the issue of sustainability concepts with increasing demands in recycling technologies. Recovery of post-consumer packaging waste is a major topic in this respect. However, contamination with odorous constituents currently curtails the production of recycling products that meet the high expectations of both consumers and industry. To guarantee odor-free recyclates, the main prerequisite is to characterize the molecular composition of the causative odorants in post-consumer plastic packaging waste...
January 30, 2017: Journal of Separation Science
https://www.readbyqxmd.com/read/28005586/sudden-death-from-ruptured-intracranial-vascular-malformations-during-mechanical-asphyxia-a-domestic-violence-case-report
#18
Xue-Mei Wu, Xu-Dong Zhang, Li-Bing Yun, Min Liu, Xu-Fu Yi
Smothering and manual strangulation are not uncommon in domestic violence against women; however, no report on the combination of mechanical asphyxia and intracranial vascular malformations has been previously published. We report a middle-aged woman who was smothered and manually strangled by her husband and subsequently died from subarachnoid hemorrhage due to ruptured intracranial vascular malformations, rather than direct mechanical asphyxiation. Smothering and manual strangulation are considered provocative conditions for rupture and contributory causes of death...
March 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/27926848/constriction-by-dynamin-elasticity-versus-adhesion
#19
COMPARATIVE STUDY
Zachary A McDargh, Pablo Vázquez-Montejo, Jemal Guven, Markus Deserno
Any cellular fission process is completed when the neck connecting almost-separate membrane compartments is severed. This crucial step is somehow accomplished by proteins from the dynamin family, which polymerize into helical spirals around such necks. Much research has been devoted to elucidating the specifics of that somehow, but despite no shortage of ideas, the question is not settled. Pictorially obvious notions of strangling or pushing are difficult to render in mechanically precise terms. Moreover, because dynamin is a GTPase, it is tempting to speculate that it has a motor activity that assists the necessary severing action, but again the underlying mechanics is not obvious...
December 6, 2016: Biophysical Journal
https://www.readbyqxmd.com/read/27866691/vocal-parameters-and-self-perception-in-individuals-with-adductor-spasmodic-dysphonia
#20
Gleidy Vannesa E Rojas, Hilton Ricz, Vitor Tumas, Guilherme R Rodrigues, Patrícia Toscano, Lílian Aguiar-Ricz
OBJECTIVE: The study aimed to compare and correlate perceptual-auditory analysis of vocal parameters and self-perception in individuals with adductor spasmodic dysphonia before and after the application of botulinum toxin. STUDY DESIGN: This is a prospective cohort study. METHODS: Sixteen individuals with a diagnosis of adductor spasmodic dysphonia were submitted to the application of botulinum toxin in the thyroarytenoid muscle, to the recording of a voice signal, and to the Voice Handicap Index (VHI) questionnaire before the application and at two time points after application...
November 17, 2016: Journal of Voice: Official Journal of the Voice Foundation
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