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https://www.readbyqxmd.com/read/27926848/constriction-by-dynamin-elasticity-versus-adhesion
#1
Zachary A McDargh, Pablo Vázquez-Montejo, Jemal Guven, Markus Deserno
Any cellular fission process is completed when the neck connecting almost-separate membrane compartments is severed. This crucial step is somehow accomplished by proteins from the dynamin family, which polymerize into helical spirals around such necks. Much research has been devoted to elucidating the specifics of that somehow, but despite no shortage of ideas, the question is not settled. Pictorially obvious notions of strangling or pushing are difficult to render in mechanically precise terms. Moreover, because dynamin is a GTPase, it is tempting to speculate that it has a motor activity that assists the necessary severing action, but again the underlying mechanics is not obvious...
December 6, 2016: Biophysical Journal
https://www.readbyqxmd.com/read/27866691/vocal-parameters-and-self-perception-in-individuals-with-adductor-spasmodic-dysphonia
#2
Gleidy Vannesa E Rojas, Hilton Ricz, Vitor Tumas, Guilherme R Rodrigues, Patrícia Toscano, Lílian Aguiar-Ricz
OBJECTIVE: The study aimed to compare and correlate perceptual-auditory analysis of vocal parameters and self-perception in individuals with adductor spasmodic dysphonia before and after the application of botulinum toxin. STUDY DESIGN: This is a prospective cohort study. METHODS: Sixteen individuals with a diagnosis of adductor spasmodic dysphonia were submitted to the application of botulinum toxin in the thyroarytenoid muscle, to the recording of a voice signal, and to the Voice Handicap Index (VHI) questionnaire before the application and at two time points after application...
November 17, 2016: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/27651915/streptococcus-equi-subspecies-equi-in-horses-in-israel-seroprevalence-and-strain-types
#3
S Tirosh-Levy, S E Blum, K F Steward, A S Waller, A Steinman
The purpose of this cross-sectional study was to determine the seroprevalence of Streptococcus equi in Israel, to monitor seropositive horses over time and to identify archived strains that were recovered from Israeli horses. A serological survey of 200 healthy horses on 20 farms throughout Israel was performed to detect recent exposure to S equi antigens A and C via indirect ELISA. Seroprevalence was 9.5 per cent (19/200) and positive horses were found in 30 per cent (6/20) of the farms. Sixteen horses that returned a positive serology result were retested three and six months later...
2016: Veterinary Record Open
https://www.readbyqxmd.com/read/27651668/strangles-in-arabian-horses-in-egypt-clinical-epidemiological-hematological-and-biochemical-aspects
#4
Ahmed N F Neamat-Allah, Hend M El Damaty
AIM: Respiratory tract infections are considered the major problem of equine worldwide. Strangles is an infectious and highly contagious respiratory bacterial disease of equine caused by Streptococcus equi. This study is aimed to evaluate some clinical and epidemiological investigation associated with strangles and to study the hematological and biochemical changes in 20 Arabian horse naturally infected with S. equi during the disease and after 10 days from treatment by procaine penicillin with benzathine penicillin...
August 2016: Veterinary World
https://www.readbyqxmd.com/read/27568034/bowel-strangulation-caused-by-massive-intraperitoneal-adhesion-due-to-effective-chemotherapy-for-multiple-peritoneal-metastases-originating-from-descending-colon-cancer
#5
Nobutoshi Horii, Daisuke Morioka, Kazuya Yamaguchi, Yoshiki Sato, Masaru Miura, Mikiko Tanabe
We describe a case of bowel strangulation caused by massive peritoneal adhesion as a result of effective chemotherapy. A 71-year-old man, who had obstructive descending colon cancer with massive peritoneal metastases and, therefore, received palliative surgery consisting of diverting colostomy and sampling of peritoneal nodules, developed bowel strangulation on day 4 of the 2nd course of chemotherapy, including irinotecan, l-leucovorin, and 5-fluorouracil. Emergent celiotomy showed a massive intraperitoneal adhesion formed around several intestinal loops, which were not observed at the prior surgery...
October 2016: Clinical Journal of Gastroenterology
https://www.readbyqxmd.com/read/27337704/strangulation-induced-central-retinal-artery-occlusion-case-report-and-review-of-the-literature
#6
Margaret A Greven, Darius M Moshfeghi
PURPOSE: To describe a patient with central retinal artery occlusion following an episode of mechanical strangulation. METHODS: A retrospective case report. An 83-year-old man presented with acute vision loss in his right eye after a strangling episode. Multimodal clinical imaging was performed. RESULTS: Visual acuity in the affected right eye was no light perception. Examination revealed optic nerve edema and optic nerve pallor and also severe vascular attenuation and a cherry-red spot in the macula...
June 22, 2016: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/27317457/detection-and-differentiation-of-wild-type-and-a-vaccine-strain-of-streptococcus-equi-ssp-equi-using-pyrosequencing
#7
Julia L Livengood, Saraswathi Lanka, Carol Maddox, Deepanker Tewari
Streptococcus equi subspecies equi (S. equi), the causative agent of strangles, is an important equine pathogen. Strangles is a highly contagious disease and a commercial modified live vaccine (MLV) is used for protection, which although effective, may also result in clinical signs of the disease. A rapid means to differentiate between the MLV and wild-type infection is crucial for quarantine release and limiting the disease spread. This study describes the use of a pyrosequencing assay targeting a single nucleotide deletion upstream of the SzPSe gene to distinguish between the wild-type and vaccine strains...
July 25, 2016: Vaccine
https://www.readbyqxmd.com/read/27311083/accidental-strangulation-due-to-entrapment-of-saree-in-crop-thrasher-machine-in-an-elderly-women-working-at-agricultural-field
#8
Manoj Bhausaheb Parchake, Vikas Kumre, Rajesh V Kachare
Strangulation is generally considered as homicidal death and in accidental strangulation circumstantial evidence alone can point toward the accidental nature of incidence. In present case, a 71-year-old woman, wearing a saree (garment worn by traditional women in India) working in agricultural field, got entangled in the crop thrasher machine and got strangled. Immediately, she was taken to the nearest hospital, where she survived for 6 to 8 hours and then died. The autopsy reveals cross ribbon-shaped ligature mark on neck and anterior chest along with 1 puncture wound at the right lateral aspect of the neck...
September 2016: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/27308820/recognition-and-documentation-of-strangulation-crimes-a-review
#9
Michael Armstrong, Gael B Strack
IMPORTANCE: Strangulation accounts for 10% of violent deaths in the United States and 15% to 20% of deaths associated with domestic violence. However, strangulation deaths represent only a small fraction of nonfatal strangulation assaults, which occur with daily frequency in medium to large US cities. Careful evaluation and documentation of strangulation injuries may identify life-threatening medical conditions, and may facilitate prosecution of strangulation crimes. OBSERVATIONS: The most recent article on strangulation identified in the otolaryngology literature was published in 1989, leaving a generation of head and neck surgeons without current guidance regarding this injury...
September 1, 2016: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/27232826/repeated-suicide-attempts-and-suicide-among-individuals-with-a-first-emergency-department-contact-for-attempted-suicide-a-prospective-nationwide-danish-register-based-study
#10
Izabela E Fedyszyn, Annette Erlangsen, Carsten Hjorthøj, Trine Madsen, Merete Nordentoft
OBJECTIVE: Emergency departments are important, albeit underutilized, sites for suicide prevention. Preventive strategies and interventions could benefit from a greater understanding of factors influencing the course of suicide risk after emergency department contact due to attempted suicide. The aim of our study was 2-fold: to identify predictors of repeated suicide attempts and suicide and to investigate the timing of these events. METHODS: Data from Danish nationwide, longitudinal registers were used in this prospective, population-based study of all individuals first presenting to an emergency department after attempted suicide (index attempt) between January 1, 1996, and December 31, 2011 (N = 11,802)...
June 2016: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/26945742/natural-death-in-the-setting-of-autoerotic-practice
#11
Yeliena Baber, Eleanor Bott
Deaths in an autoerotic setting are usually due to accidental asphyxia, in which the individual accidently hangs or strangles themselves while inducing hypoxia for the purpose of heightened arousal. Death occurs when the level of hypoxia causes the individual to lose consciousness and is thus unable to prevent the neck compression from becoming lethal. In some cases there is an "escape" mechanism incorporated into the set-up which may fail. In rare cases, death is not as an immediate result of the autoerotic activity and is as a result of natural causes, which may or may not be related to the process...
June 2016: Forensic Science, Medicine, and Pathology
https://www.readbyqxmd.com/read/26907718/airway-stent-what-is-new-and-what-should-be-discarded
#12
REVIEW
Felix J F Herth, Ralf Eberhardt
PURPOSE OF REVIEW: Patients with lung cancer often develop endobronchial disease, endobronchial tumor extension or airway compression. Various nonmalignant diseases can also lead to severe central airway obstruction.Since the early 1980s, technical advances of interventional bronchoscopic techniques have improved symptom-free survival and quality of life for patients with lung cancer. Apart from other techniques, various airway stents have been developed. Although interventional procedures are not definitive therapies, they often relieve the strangling sensation produced by airway occlusion...
May 2016: Current Opinion in Pulmonary Medicine
https://www.readbyqxmd.com/read/26850537/prevalence-of-streptococcus-equi-subsp-equi-in-horses-and-associated-risk-factors-in-the-state-of-rio-grande-do-sul-brazil
#13
Felipe Libardoni, Gustavo Machado, Letícia Trevisan Gressler, Ananda Paula Kowalski, Gustavo Nogueira Diehl, Lucila Carboneiro dos Santos, Luis Gustavo Corbellini, Agueda Castagna de Vargas
The aim of this study was to estimate the prevalence of equine strangles and to identify associated risk factors for this disease through a cross-sectional study of nasal swabs. Nasal swabs (n=1010) from healthy equines (absence of nasal discharge, lymphadenopathy and cough) from 341 farms were plated on 5% blood agar; of these horses, 24 were identified as positive for Streptococcus equi through isolation, PCR and DNA sequencing. The estimated prevalence for individual animals was 2.3%, and for herds, it was 5...
February 2016: Research in Veterinary Science
https://www.readbyqxmd.com/read/26811303/voice-tuning-with-new-instruments-for-type-ii-thyroplasty-in-the-treatment-of-adductor-spasmodic-dysphonia
#14
Tetsuji Sanuki, Eiji Yumoto, Yutaka Toya, Yoshihiko Kumai
OBJECTIVE: Adductor spasmodic dysphonia is a rare voice disorder characterized by strained and strangled voice quality with intermittent phonatory breaks and adductory vocal fold spasms. Type II thyroplasty differs from previous treatments in that this surgery does not involve any surgical intervention into the laryngeal muscle, nerve or vocal folds. Type II thyroplasty intervenes in the thyroid cartilage, which is unrelated to the lesion. This procedure, conducted with the aim of achieving lateralization of the vocal folds, requires utmost surgical caution due to the extreme delicacy of the surgical site, critically sensitive adjustment, and difficult procedures to maintain the incised cartilages at a correct position...
January 22, 2016: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/26795860/strangles-a-pathogenic-legacy-of-the-war-horse
#15
REVIEW
Andrew S Waller
Strangles, characterised by pyrexia followed by abscessation of the lymph nodes of the head and neck, was first described in 1251 (Rufus 1251) and the causative agent, Streptococcus equi, was identified in 1888 (Schutz 1888). However, despite more than a century of research into this disease, strangles remains the most frequently diagnosed infection of horses with over 600 outbreaks being identified in the UK alone each year (Parkinson and others 2011). Here, Andrew Waller reviews some of the recent advances in the understanding of the evolution of S equi and puts this into the context of preventing and resolving outbreaks of infection...
January 23, 2016: Veterinary Record
https://www.readbyqxmd.com/read/26654837/the-epidemiology-of-homicidal-strangulation-in-the-city-of-johannesburg-south-africa
#16
Shahnaaz Suffla, Mohamed Seedat
Studies that provide accurate descriptions of the occurrence of fatal strangulation events are limited, both in South Africa and elsewhere in the world. The current study describes the extent and distribution of female and male homicidal strangulation in the City of Johannesburg for the period 2001-2010. The study is a register-based cross sectional study of homicidal strangulation that draws on data recorded by the National Injury Mortality Surveillance System. Crude, unadjusted strangulation rates, and proportions of strangulation across specific circumstances of occurrence were computed for each year and aggregated in some instances...
January 2016: Journal of Forensic and Legal Medicine
https://www.readbyqxmd.com/read/26517620/predictor-variables-for-and-complications-associated-with-streptococcus-equi-subsp-equi-infection-in-horses
#17
Lauren R Duffee, Darko Stefanovski, Raymond C Boston, Ashley G Boyle
OBJECTIVE: To evaluate predictor variables for and complications associated with Streptococcus equi subsp equi infection (strangles) in horses. DESIGN: Retrospective case-control study. ANIMALS: 108 horses with strangles (cases) and 215 horses without strangles (controls). PROCEDURES: Medical records from January 2005 through July 2012 were reviewed. Cases were defined as horses with clinical signs of strangles (pyrexia, retropharyngeal lymphadenopathy, and mucopurulent nasal discharge) that were associated with a confirmed strangles outbreak or had positive results for S equi on PCR assay or bacteriologic culture...
November 15, 2015: Journal of the American Veterinary Medical Association
https://www.readbyqxmd.com/read/26438915/practical-management-of-strangles-outbreaks-in-horses
#18
Rena Richmond
No abstract text is available yet for this article.
August 2015: Australian Veterinary Journal
https://www.readbyqxmd.com/read/26436242/children-s-and-adults-comfort-experience-of-extra-seat-belts-when-riding-in-the-rear-seat-of-a-passenger-car
#19
Anna-Lisa Osvalder, Ida Hansson, Katarina Bohman
OBJECTIVE: The objective of this study was to explore passengers' comfort experience of extra seat belts during on-road driving in the rear seat of a passenger car and to investigate how the use of extra belts affects children's and adults' attitudes to the product. METHODS: Two different seat belt systems were tested, criss-cross (CC) and backpack (BP), consisting of the standard 3-point belt together with an additional 2-point belt. In total, 32 participants (15 children aged 6-10, 6 youths aged 11-15, and 11 adults aged 20-79, who differed considerably in size, shape, and proportions) traveled for one hour with each system, including city traffic and highway driving...
2015: Traffic Injury Prevention
https://www.readbyqxmd.com/read/26412899/spinal-cord-herniation-with-characteristic-bone-change-a-case-report
#20
Tasuku Imai, Yukimi Nakane, Eiji Tachibana, Koichiro Ogura
Spinal cord herniation (SCH) is a rare disease characterized by herniation of the thoracic spinal cord through an anterior dural defect, presenting with progressive myelopathy. A case of a 69-year-old woman who presented with Brown-Sequard syndrome and a bone defect, in which an osteophyte created a hemisphere-like cavity with spinal cord herniation, is presented. The strangled spinal cord was released, and the defect was closed microsurgically using an artificial dural patch to prevent re-herniation. Postoperatively, the patient experienced gradual improvement in neurologic function...
August 2015: Nagoya Journal of Medical Science
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