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https://www.readbyqxmd.com/read/29149332/kidney-sales-and-market-regulation-a-reply-to-semrau
#1
Julian J Koplin
Luke Semrau argues that the documented harms of existing organ markets do not undermine the case for establishing regulated systems of paid kidney donation. He offers two arguments in support of this conclusion. First, Semrau argues that the harms of kidney selling are straightforwardly amenable to regulatory solution. Second, Semrau argues that even in existing black markets, sellers would likely have experienced greater harm if the option of selling a kidney were not available. This commentary challenges both of Semrau's claims...
November 15, 2017: Journal of Medicine and Philosophy
https://www.readbyqxmd.com/read/29146534/systematic-review-for-the-2017-acc-aha-aapa-abc-acpm-ags-apha-ash-aspc-nma-pcna-guideline-for-the-prevention-detection-evaluation-and-management-of-high-blood-pressure-in-adults-a-report-of-the-american-college-of-cardiology-american-heart-association-task
#2
David M Reboussin, Norrina B Allen, Michael E Griswold, Eliseo Guallar, Yuling Hong, Daniel T Lackland, Edgar Pete R Miller, Tamar Polonsky, Angela M Thompson-Paul, Suma Vupputuri
OBJECTIVE: To review the literature systematically and perform meta-analyses to address these questions: 1) Is there evidence that self-measured blood pressure (BP) without other augmentation is superior to office-based measurement of BP for achieving better BP control or for preventing adverse clinical outcomes that are related to elevated BP? 2) What is the optimal target for BP lowering during antihypertensive therapy in adults? 3) In adults with hypertension, how do various antihypertensive drug classes differ in their benefits and harms compared with each other as first-line therapy? METHODS: Electronic literature searches were performed by Doctor Evidence, a global medical evidence software and services company, across PubMed and EMBASE from 1966 to 2015 using key words and relevant subject headings for randomized controlled trials that met eligibility criteria defined for each question...
November 7, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/29133355/systematic-review-for-the-2017-acc-aha-aapa-abc-acpm-ags-apha-ash-aspc-nma-pcna-guideline-for-the-prevention-detection-evaluation-and-management-of-high-blood-pressure-in-adults-a-report-of-the-american-college-of-cardiology-american-heart-association-task
#3
REVIEW
David M Reboussin, Norrina B Allen, Michael E Griswold, Eliseo Guallar, Yuling Hong, Daniel T Lackland, Edgar Pete R Miller, Tamar Polonsky, Angela M Thompson-Paul, Suma Vupputuri
OBJECTIVE: To review the literature systematically and perform meta-analyses to address these questions: 1) Is there evidence that self-measured blood pressure (BP) without other augmentation is superior to office-based measurement of BP for achieving better BP control or for preventing adverse clinical outcomes that are related to elevated BP? 2) What is the optimal target for BP lowering during antihypertensive therapy in adults? 3) In adults with hypertension, how do various antihypertensive drug classes differ in their benefits and harms compared with each other as first-line therapy? METHODS: Electronic literature searches were performed by Doctor Evidence, a global medical evidence software and services company, across PubMed and EMBASE from 1966 to 2015 using key words and relevant subject headings for randomized controlled trials that met eligibility criteria defined for each question...
November 13, 2017: Hypertension
https://www.readbyqxmd.com/read/29108153/gender-dysphoria-in-children
#4
(no author information available yet)
Gender dysphoria (GD) of childhood describes a psychological condition in which children experience a marked incongruence between their experienced gender and the gender associated with their biological sex. When this occurs in the pre-pubertal child, GD resolves in the vast majority of patients by late adolescence. Currently there is a vigorous, albeit suppressed, debate among physicians, therapists, and academics regarding what is fast becoming the new treatment standard for GD in children. This new paradigm is rooted in the assumption that GD is innate, and involves pubertal suppression with gonadotropin releasing hormone (GnRH) agonists followed by the use of cross-sex hormones-a combination that results in the sterility of minors...
2017: Issues in Law & Medicine
https://www.readbyqxmd.com/read/29036923/environmental-impact-and-relative-invasiveness-of-free-roaming-domestic-carnivores-a-north-american-survey-of-governmental-agencies
#5
Ana Lepe, Valerie Kaplan, Alirio Arreaza, Robert Szpanderfer, David Bristol, M Scott Sinclair
A survey of the United States and Canadian governmental agencies investigated the environmental impact and relative invasiveness of free-roaming domestic non-native carnivores-dogs, cats, and ferrets. Agencies represented wildlife, fish, game, natural or environmental resources, parks and recreation, veterinary and human health, animal control, and agriculture. Respondents were asked to document the number and frequency of sightings of unconfined animals, evidence for environmental harm, and the resulting "degree of concern" in their respective jurisdictions...
October 14, 2017: Animals: An Open Access Journal From MDPI
https://www.readbyqxmd.com/read/29035175/lifestyle-medicine-a-brief-review-of-its-dramatic-impact-on-health-and-survival
#6
Balazs I Bodai, Therese E Nakata, William T Wong, Dawn R Clark, Steven Lawenda, Christine Tsou, Raymond Liu, Linda Shiue, Neil Cooper, Michael Rehbein, Benjamin P Ha, Anne Mckeirnan, Rajiv Misquitta, Pankaj Vij, Andrew Klonecke, Carmelo S Mejia, Emil Dionysian, Sean Hashmi, Michael Greger, Scott Stoll, Thomas M Campbell
By ignoring the root causes of disease and neglecting to prioritize lifestyle measures for prevention, the medical community is placing people at harm. Advanced nations, influenced by a Western lifestyle, are in the midst of a health crisis, resulting largely from poor lifestyle choices. Epidemiologic, ecologic, and interventional studies have repeatedly indicated that most chronic illnesses, including cardiovascular disease, cancer, and type 2 diabetes, are the result of lifestyles fueled by poor nutrition and physical inactivity...
2017: Permanente Journal
https://www.readbyqxmd.com/read/29028953/overutilization-of-antibiotics-in-children-with-diarrhea-first-do-no-harm
#7
Timothy Jones
No abstract text is available yet for this article.
September 26, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29025107/vanishing-twin-syndrome-among-art-singletons-and-pregnancy-outcomes
#8
Maria C Magnus, Sara Ghaderi, Nils-Halvdan Morken, Per Magnus, Liv Bente Romundstad, Rolv Skjærven, Allen J Wilcox, Siri Eldevik Håberg
STUDY QUESTION: Among babies born by ART, do singleton survivors of a vanishing twin have lower birth weight than other singletons? SUMMARY ANSWER: Vanishing twin syndrome (VTS) was associated with lower birth weight among ART singletons; a sibship analysis indicated that the association was not confounded by maternal characteristics that remain stable between deliveries. WHAT IS KNOWN ALREADY: Previous studies indicate that ART singletons with VTS have increased risk of adverse pregnancy outcomes, compared with other ART singletons...
November 1, 2017: Human Reproduction
https://www.readbyqxmd.com/read/29018588/do-chain-pharmacies-perform-better-than-independent-pharmacies-evidence-from-a-standardised-patient-study-of-the-management-of-childhood-diarrhoea-and-suspected-tuberculosis-in-urban-india
#9
Rosalind Miller, Catherine Goodman
INTRODUCTION: Pharmacies and drug stores are frequently patients' first point of care in many low-income and middle-income countries, but their practice is often poor. Pharmacy retailing in India has traditionally been dominated by local, individually owned shops, but recent years have seen the growth of pharmacy chains. In theory, lower-powered profit incentives and self-regulation to preserve brand identity may lead to higher quality in chain stores. In practice, this has been little studied...
2017: BMJ Global Health
https://www.readbyqxmd.com/read/28994633/endovascular-aneurysm-repair-in-the-elderly-first-do-no-harm
#10
Mahim I Qureshi, Alun H Davies
Endovascular aneurysm repair (EVAR) has become the intervention of choice for supra-threshold aortic aneurysms due to the lower 30-day mortality of EVAR as compared with open surgery, despite no long-term longevity gains. Trials such as EVAR-1 that established the current status of endovascular aortic intervention often excluded participants over the age of 80, and specific studies of EVAR in the elderly reveal higher mortality than accepted averages. Analyses of the cost-effectiveness of EVAR have not demonstrated superiority of endovascular intervention over open repair, in particular when considering complications such as endoleak...
January 1, 2017: Vascular
https://www.readbyqxmd.com/read/28973619/effect-of-routine-low-dose-oxygen-supplementation-on-death-and-disability-in-adults-with-acute-stroke-the-stroke-oxygen-study-randomized-clinical-trial
#11
RANDOMIZED CONTROLLED TRIAL
Christine Roffe, Tracy Nevatte, Julius Sim, Jon Bishop, Natalie Ives, Phillip Ferdinand, Richard Gray
Importance: Hypoxia is common in the first few days after acute stroke, is frequently intermittent, and is often undetected. Oxygen supplementation could prevent hypoxia and secondary neurological deterioration and thus has the potential to improve recovery. Objective: To assess whether routine prophylactic low-dose oxygen therapy was more effective than control oxygen administration in reducing death and disability at 90 days, and if so, whether oxygen given at night only, when hypoxia is most frequent, and oxygen administration is least likely to interfere with rehabilitation, was more effective than continuous supplementation...
September 26, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/28971305/screening-and-treatment-for-early-onset-gestational-diabetes-mellitus-a-systematic-review-and-meta-analysis
#12
REVIEW
Jincy Immanuel, David Simmons
We conducted a systematic review to evaluate the current evidence for screening and treatment for early-onset gestational diabetes mellitus (GDM) RECENT FINDINGS: Many of the women with early GDM in the first trimester do not have evidence of hyperglycemia at 24-28 weeks' gestation. A high proportion (15-70%) of women with GDM can be detected early in pregnancy depending on the setting, criteria used and screening strategy. However, there remains no good evidence for any of the diagnostic criteria for early-onset GDM...
October 2, 2017: Current Diabetes Reports
https://www.readbyqxmd.com/read/28963999/-communicate-medical-errors-or-hide-them-in-relation-to-the-henry-marsh-s-memoirs
#13
Eugenio Moure González
″Do no harm″ is the work of Henry Marsh, an English neurosurgeon who, in the epilogue of his professional career at the National Health Service, remembers not only his professional successes but also his failures. This is the starting point to propose a system of notification of medical errors in Spain that allows to comply with the hippocratic key principle that gives title to the book: ″primum non nocere″. With this objective, our proposal is, in first place, to analyze the extent to which there is a conflict of loyalties in the professional performance of any doctor (institution vs...
September 2017: Cuadernos de Bioética: Revista Oficial de la Asociación Española de Bioética y Ética Médica
https://www.readbyqxmd.com/read/28958200/one-eye-of-the-future-one-eye-on-the-past
#14
Cathal T Gallagher, Chhayal Dhokia
Purpose The purpose of this paper is to assess if the GOC considers relevant factors at all stages of its deliberations into misconduct, as required by the determinations in the cases of Cohen, Zygmunt, and Azzam, and to assess whether those circumstances described in the Hearings Guidance and Indicative Sanctions as warranting removal of an optician from the relevant registers lead to that outcome. Design/methodology/approach The consideration of specific factors in determining impairment of fitness to practise was compared with their subsequent consideration when determining the severity of sanction...
October 9, 2017: International Journal of Health Care Quality Assurance
https://www.readbyqxmd.com/read/28951264/discussing-sarcoma-risks-during-informed-consent-for-nonhysterectomy-management-of-fibroids-an-unmet-need
#15
Brandon-Luke L Seagle, Amy L Alexander, Anna E Strohl, Shohreh Shahabi
There is no reliable way to distinguish symptomatic uterine fibroids from sarcoma without a surgical specimen. Many women with a uterine sarcoma are initially managed without hysterectomy under a presumed fibroid diagnosis, without understanding sarcoma risks. Currently many alternatives to hysterectomy, including medical and procedural interventions, for treatment of fibroids are promoted. The sarcoma incidence among women with presumed fibroids is 0.29% (1/340) to 0.05% (1/2000). Nonmetastatic leiomyosarcoma has a 63% 5-year survival rate whereas metastatic leiomyosarcoma has a 14% 5-year survival rate...
September 23, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28947676/effective-engaging-secure-applying-the-orcha-24-framework-to-evaluate-apps-for-chronic-insomnia-disorder
#16
Simon Leigh, Jing Ouyang, Chris Mimnagh
BACKGROUND: Mobile health offers many opportunities; however, the 'side-effects' of health apps are often unclear. With no guarantee health apps first do no harm, their role as a viable, safe and effective therapeutic option is limited. OBJECTIVE: To assess the quality of apps for chronic insomnia disorder, available on the Android Google Play Store, and determine whether a novel approach to app assessment could identify high-quality and low-risk health apps in the absence of indicators such as National Health Service (NHS) approval...
September 25, 2017: Evidence-based Mental Health
https://www.readbyqxmd.com/read/28932929/-first-do-no-harm-adverse-events-from-pharmaceutical-treatment-of-gastroparesis-and-dyspepsia
#17
EDITORIAL
Thomas M Goodsall, Nicholas J Talley
No abstract text is available yet for this article.
November 2017: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/28912976/electromagnetic-interference-from-swimming-pool-generator-current-causing-inappropriate-icd-discharges
#18
Edward Samuel Roberto, Thein Tun Aung, Atif Hassan, Abdul Wase
Electromagnetic interference (EMI) includes any electromagnetic field signal that can be detected by device circuitry, with potentially serious consequences: incorrect sensing, pacing, device mode switching, and defibrillation. This is a unique case of extracardiac EMI by alternating current leakage from a submerged motor used to recycle chlorinated water, resulting in false rhythm detection and inappropriate ICD discharge. A 31-year-old female with arrhythmogenic right ventricular cardiomyopathy and Medtronic dual-chamber ICD placement presented after several inappropriate ICD shocks at the public swimming pool...
2017: Case Reports in Cardiology
https://www.readbyqxmd.com/read/28899714/qualitative-evaluation-of-a-narrative-reflection-program-to-help-medical-trainees-recognize-and-avoid-overuse-am-i-doing-what-s-right-for-the-patient
#19
Tanner Caverly, Daniel Matlock, Jocelyn Thompson, Brandon Combs
OBJECTIVE: The Do No Harm Project is a novel reflective writing program that encourages medical trainees to reflect on and write up clinical narratives about instances of avoidable medical overuse. Our goal is to describe this program and to explore the effect of the program on those participating. METHODS: Semi-structured interviews were conducted to explore how participating in the project influenced the thinking, attitudes, and behaviors of participating internal medicine residents...
September 8, 2017: Patient Education and Counseling
https://www.readbyqxmd.com/read/28821684/medication-overuse-headache-an-entrenched-idea-in-need-of-scrutiny
#20
REVIEW
Ann I Scher, Paul B Rizzoli, Elizabeth W Loder
It is a widely accepted idea that medications taken to relieve acute headache pain can paradoxically worsen headache if used too often. This type of secondary headache is referred to as medication overuse headache (MOH); previously used terms include rebound headache and drug-induced headache. In the absence of consensus about the duration of use, amount, and type of medication needed to cause MOH, the default position is conservative. A common recommendation is to limit treatment to no more than 10 or 15 days per month (depending on medication type) to prevent headache frequency progression...
September 19, 2017: Neurology
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