keyword
https://read.qxmd.com/read/36968885/hypertension-in-the-neonatal-intensive-care-unit-nicu-a-case-of-mid-aortic-syndrome
#1
Ayesha Ropri, Jess Randall
A term baby was born with findings of edema, harsh murmur, and hypertension. Pregnancy course was complicated by hydrops fetalis. Upon birth, blood work did not reveal any abnormalities, but an echocardiogram showed patient in high-output heart failure. A computed tomography (CT) chest, abdomen, and pelvis revealed narrowing of aorta in the thoracic region to distal iliac and renal arteries, consistent with mid-aortic syndrome. Mid-aortic syndrome, which results in the narrowing of thoracic or abdominal aorta, is a rare cause of hypertension, especially in newborns...
February 2023: Curēus
https://read.qxmd.com/read/32446928/effects-of-stem-bark-aqueous-extract-of-fagara-tessmannii-engl-rutaceae-on-cardiovascular-risks-related-to-monosodium-glutamate-induced-obesity-in-rat-in-vivo-and-in-vitro-assessments
#2
JOURNAL ARTICLE
Yannick Bekono Fouda, Esther Ngo Lemba Tom, Albert Donatien Atsamo, Christian Bonabe, Théophile Dimo
ETHNOPHARMACOLOGICAL RELEVANCE: Fagara tessmannii is a shrub of the African rainforests in South-West, Centre, South and East provinces in Cameroon. It is used in traditional medicine for the treatment of tumors, swellings, inflammation, gonorrhoea, schistosomiasis, antifungal, heart diseases and as anti-hypertensive. AIM OF THE STUDY: We investigated the potential effects of F. tessmannii on cardiovascular risk related to monosodium glutamate-induced obesity. MATERIALS AND METHODS: Monosodium glutamate (MSG, 4 mg/g/day) was injected subcutaneously to newborn Wistar rats for the four consecutive first days of their life and on the 6th, 8th and 10th day after birth...
October 5, 2020: Journal of Ethnopharmacology
https://read.qxmd.com/read/31061719/hypertension-secondary-to-renal-hypoplasia-presenting-as-acute-heart-failure-in-a-newborn
#3
Jena Deitrick, Kayle Stevenson, Daniel Nguyen, William Sessions, Vijay Linga, Tetyana Vasylyeva
INTRODUCTION: Neonatal hypertension is defined as persistent systolic and/or diastolic blood pressures above the 95th percentile compared to other infants of similar gestational age and size. Neonatal hypertension is a rare condition, occurring in only 0.2-3.0% of neonates. The most common etiology of neonatal hypertension is renal vascular or parenchymal disease, and it is usually detected on routine examination in an asymptomatic child. However, it may present in a variety of manners, including acute heart failure, renal dysfunction, feeding difficulties, failure to thrive, tachypnea, apnea, lethargy, irritability, or seizures...
2019: Clinical Hypertension
https://read.qxmd.com/read/29974208/neonatal-hypertension-an-educational-review
#4
REVIEW
Matthew W Harer, Alison L Kent
Hypertension is encountered in up to 3% of neonates and occurs more frequently in neonates requiring hospitalization in the neonatal intensive care unit (NICU) than in neonates in newborn nurseries or outpatient clinics. Former NICU neonates are at higher risk of hypertension secondary to invasive procedures and disease-related comorbidities. Accurate measurement of blood pressure (BP) remains challenging, but new standardized methods result in less measurement error. Multiple factors contribute to the rapidly changing BP of a neonate: gestational age, postmenstrual age (PMA), birth weight, and maternal factors are the most significant contributors...
June 2019: Pediatric Nephrology
https://read.qxmd.com/read/29789210/should-first-blood-pressure-measurement-be-performed-in-the-newborn
#5
JOURNAL ARTICLE
Inês Alves, Tânia Martins, Ana Luísa Neves, Esmeralda Rodrigues, Ana Teixeira, Caldas Afonso, Helena Pinto
Dilated cardiomyopathy is the most common form of cardiomyopathy and the main cause of cardiac transplantation in children and in adults. Infants and children have a wider spectrum of etiologies, hampering their identification. The most frequent initial manifestation of dilated cardiomyopathy is symptomatic heart failure during exercise or at rest (although many patients are asymptomatic). Some causes are potentially reversible, therefore the investigation should be carefully planned and immediately performed after diagnosis...
July 2018: Revista portuguesa de cardiologia
https://read.qxmd.com/read/25155725/neonatal-hypertension
#6
REVIEW
Donald L Batisky
The incidence of neonatal hypertension (HTN) remains low, at less than 2%, and its etiology is varied. Strict definitions of HTN in neonates are unavailable, and the decision to treat is based on opinion rather than evidence. More studies are needed to define normal blood pressure in neonates and to refine current reference values, thus permitting a better definition of HTN. Most causes of neonatal HTN, the most common of which seems to be renovascular disease, are determined by history and basic clinical investigations...
September 2014: Clinics in Perinatology
https://read.qxmd.com/read/24791189/managing-hypertension-in-the-newborn-infants
#7
REVIEW
Azar Nickavar, Farahnak Assadi
Hypertension in newborn infants, particularly those requiring intensive care, is becoming increasingly recognized, with prevalence of 0.2-3%. Recent studies have established normative tables for blood pressure (BP) in both term and pre-term infants based on the gestational age, postnatal age, gender, weight and height, identifying the neonates at increased risk for early-onset cardiovascular disease. Common causes of neonatal hypertension include thromboembolic complications secondary to umbilical artery catheterization, congenital renal structural malformation, renovascular disease, aortic coarctation, as well as acute kidney injury and certain medications...
March 2014: International Journal of Preventive Medicine
https://read.qxmd.com/read/22525199/hypertension-and-aortorenal-disease-in-alagille-syndrome
#8
REVIEW
Joe-Elie Salem, Eric Bruguiere, Laurence Iserin, Anne Guiochon-Mantel, Pierre-François Plouin
Alagille syndrome is a rare congenital multisystem disorder that may involve heart disease and pulmonary or peripheral artery stenosis. We report the clinical and radiological presentation of five adult patients with Alagille syndrome, hypertension and renal artery stenosis. All had systolic hypertension and a narrowing of the abdominal aorta, corresponding to a secondary midaortic syndrome. Renovascular disease progressed during follow-up, with increases in blood pressure, decreases in glomerular filtration rate and/or kidney atrophy...
July 2012: Journal of Hypertension
https://read.qxmd.com/read/22503182/extensive-congenital-abdominal-aortic-aneurysm-and-renovascular-disease-in-the-neonate
#9
JOURNAL ARTICLE
Jarod McAteer, Robert Ricca, Kaj H Johansen, Adam B Goldin
Primary congenital abdominal aortic aneurysm is an extremely rare entity, with only 15 patients reported in the literature. Options for repair are often limited secondary to branch vessel size and other anatomic limitations. We present a neonate diagnosed with an abdominal aortic aneurysm on prenatal ultrasound. A postpartum computed tomography angiogram revealed an extensive type IV thoracoabdominal aortic aneurysm extending to the aortic bifurcation and resulting in bilateral renal artery stenosis. The unique features of this patient and challenges in management are discussed...
June 2012: Journal of Vascular Surgery
https://read.qxmd.com/read/21966796/-takayasu-s-arteritis-in-pregnancy-report-seven-cases
#10
JOURNAL ARTICLE
José Antonio Hernández-Pacheco, Ariel Estrada-Altamirano, Arlen Valenzuela-Jirón, José Luis Maya-Quiñones, Javier Andrés Carvajal-Valencia, Armando Rogerio Chacón-Solís
Takayasu's arteritis is a chronic and non-specific disease of young women in reproductive age that primarily affects the aorta, its branches and the pulmonary artery. Ramirez Cueto G. and Fernandez Del Castillo C. et al. published a case of pregnancy in Mexico and Takayasu's arteritis in 1968. There are no reports of this disease in pregnancy since. The purpose of this study is to describe the clinical course and perinatal outcome of seven pregnant patients with known diagnosis of Takayasu arteritis. The clinical course, laboratory findings, angiographic findings and perinatal outcomes were assessed in retrospect in seven pregnant patients with diagnosis of Takayasu's arteritis seen at the National Institute of Perinatology Isidro Espinosa Reyes (Mexico) during the period 2002-2010...
March 2011: Ginecología y Obstetricia de México
https://read.qxmd.com/read/21926266/thromboxane-induced-actin-polymerization-in-hypoxic-pulmonary-artery-is-independent-of-rho
#11
COMPARATIVE STUDY
Jena Fediuk, Alexey Gutsol, Nora Nolette, Shyamala Dakshinamurti
Actin polymerization (APM), regulated by Rho GTPases, promotes myocyte force generation. Hypoxia is known to impede postnatal disassembly of the actin cytoskeleton in pulmonary arterial (PA) myocytes. We compared basal and agonist-induced APM in myocytes from PA and descending aorta (Ao), under hypoxic and normoxic conditions. We also examined effects of thromboxane challenge on force generation and cytoskeletal assembly in resistance PA and renal arteries from neonatal swine with persistent pulmonary hypertension (PPHN) induced by 72-h normobaric hypoxia, compared with age-matched controls...
January 1, 2012: American Journal of Physiology. Lung Cellular and Molecular Physiology
https://read.qxmd.com/read/21773822/hypertensive-crisis-in-children
#12
REVIEW
Jayanthi Chandar, Gastón Zilleruelo
Hypertensive crisis is rare in children and is usually secondary to an underlying disease. There is strong evidence that the renin-angiotensin system plays an important role in the genesis of hypertensive crisis. An important principle in the management of children with hypertensive crisis is to determine if severe hypertension is chronic, acute, or acute-on-chronic. When it is associated with signs of end-organ damage such as encephalopathy, congestive cardiac failure or renal failure, there is an emergent need to lower blood pressures to 25-30% of the original value and then accomplish a gradual reduction in blood pressure...
May 2012: Pediatric Nephrology
https://read.qxmd.com/read/21406596/hemin-decreases-cardiac-oxidative-stress-and-fibrosis-in-a-rat-model-of-systemic-hypertension-via-pi3k-akt-signalling
#13
JOURNAL ARTICLE
Morel-Elvis Worou, Karim Belmokhtar, Pierre Bonnet, Patrick Vourc'h, Marie-Christine Machet, Georges Khamis, Véronique Eder
AIMS: Angiotensin II induces cardiac myocyte apoptosis and hypertrophy, which contribute to heart failure, possibly through enhanced oxidative stress. The aim of this work was to assess the impact of hemin (heme oxygenase-1 inducer) on NADPH oxidase activation, cardiac oxidative stress, and development of fibrosis in a rat model of renovascular hypertensive cardiomyopathy in comparison to an anti-hypertensive reference treatment with losartan. METHODS AND RESULTS: A 3 week hemin treatment was tested in an angiotensin II-dependent hypertensive rat model and a cellular model of neonatal rat cardiomyocytes stimulated by angiotensin II...
July 15, 2011: Cardiovascular Research
https://read.qxmd.com/read/19685045/pediatric-renovascular-hypertension-in-thailand-ct-angiographic-findings
#14
JOURNAL ARTICLE
Pannee Visrutaratna, Tanop Srisuwan, Chusak Sirivanichai
BACKGROUND: Renovascular disease is an uncommon but important cause of hypertension in children. When unrecognized and untreated, renovascular hypertension in children can have serious complications. OBJECTIVE: To review the causes of renovascular hypertension and computed tomography angiographic (CTA) findings in children and adolescents. MATERIALS AND METHODS: Twenty-eight CTAs from January 2004 to March 2008 of 23 children and adolescents with hypertension were reviewed for the causes and CTA findings...
December 2009: Pediatric Radiology
https://read.qxmd.com/read/19341836/a-renal-protocol-for-all-ages-and-all-indications-mercapto-acetyl-triglycine-mag3-with-simultaneous-injection-of-furosemide-mag3-f0-a-17-year-experience
#15
JOURNAL ARTICLE
George N Sfakianakis, Efrosyni Sfakianaki, Mike Georgiou, Aldo Serafini, Shabbir Ezuddin, Russ Kuker, Gaston Zilleruelo, Jose Strauss, Carolyn Abitbol, Jayanthi Chandar, Wacharee Seeherunvong, Jacque Bourgoignie, David Roth, Raymond Leveillee, Vincent G Bird, Norman Block, Rafael Gosalbez, Andrew Labbie, Jorge J Guerra, Jose Yrizarry
Current clinical requirements mandate the existence of a renal diuretic protocol, which is fast and easy, applicable in all ages and for all indications, convenient for both the patient and the technologist, and provides diagnostic as well as prognostic information. Seventeen years ago a 25-minute protocol, after oral hydration, with no bladder catheterization, and simultaneous injection of mercapto-acetyl-triglycine (MAG(3)) and furosemide (MAG(3)-F(0)), was initiated. It initially was used for the evaluation of drainage and emerged as a protocol to also evaluate the renal parenchyma...
May 2009: Seminars in Nuclear Medicine
https://read.qxmd.com/read/18320235/idiopathic-mid-aortic-syndrome-in-children
#16
REVIEW
Christine B Sethna, Bernard S Kaplan, Anne Marie Cahill, Omaida C Velazquez, Kevin E C Meyers
Mid-aortic syndrome (MAS) is an uncommon condition characterized by narrowing of the abdominal aorta and stenosis of its major branches. Our goal was to illustrate the presentation, diagnosis and management of six new cases of idiopathic MAS together with 96 cases of idiopathic MAS from the literature. The mean age of the 102 cases was 14.3 years (19 days to 49 years). Our patient who presented at 19 days of age is the youngest reported to date. Clinical presentations included hypertension (94%), claudication (17%), renal failure (4%) and intestinal ischemia (1%)...
July 2008: Pediatric Nephrology
https://read.qxmd.com/read/18293686/-neonatal-hypertension-diagnostic-and-therapeutic-approach
#17
REVIEW
Larisia Mihai
Hypertension in the neonate is a rare disease. Although the definition of hypertension in this age group has not been completely standardized, recent studies have provided new normative data that may be used to facilitate identification of such infants. The most common causes of clinically and treatable hypertension in neonates is renal artery occlusion due to thromboembolic events related to umbilical catheterization. Additionally, congenital problems such as aortic coarctation, structural renal malformations and renovascular disease, as well as acquired renal disease and certain medications must always be considered...
July 2007: Revista Medico-chirurgicală̆ a Societă̆ţ̜ii de Medici ş̧i Naturaliş̧ti Din Iaş̧i
https://read.qxmd.com/read/18060446/midaortic-syndrome-presenting-as-neonatal-hypertension
#18
JOURNAL ARTICLE
Bibhuti B Das, Michael Recto, Lawrence Shoemaker, Michael Mitchell, Erle H Austin
We describe a case of mid-aortic syndrome presenting as systemic hypertension in infancy and early childhood. Angiography of the descending and abdominal aorta is the diagnostic test of choice to confirm the diagnosis of mid-aortic syndrome. Severity of hypertension is one of the major factors in determining the timing of intervention. Because of variability in the anatomic extent of mid-aortic syndrome, management options need to be individualized.
September 2008: Pediatric Cardiology
https://read.qxmd.com/read/17585094/renal-artery-thrombosis-and-ischaemia-presenting-as-severe-neonatal-hypertension
#19
JOURNAL ARTICLE
H S Lam, W C W Chu, C H Lee, W Wong, P C Ng
No abstract text is available yet for this article.
July 2007: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://read.qxmd.com/read/17534666/reno-vascular-hypertension-in-childhood-a-nationwide-survey
#20
JOURNAL ARTICLE
Aysun K Bayazit, Fatos Yalcinkaya, Nilgun Cakar, Ali Duzova, Zelal Bircan, Aysin Bakkaloglu, Nur Canpolat, Nazl Kara, Aydan Sirin, Mesiha Ekim, Ayse Oner, Sema Akman, Sevgi Mir, Esra Baskin, Hakan M Poyrazoglu, Aytul Noyan, Ipek Akil, Sevcan Bakkaloglu, Alper Soylu
Renovascular disease accounts for 8-10% of all cases of paediatric hypertension, whereas, in adults, its incidence is approximately 1%. The Turkish Paediatric Hypertension Group aimed to create the first registry database for childhood renovascular hypertension in Turkey. Twenty of the 28 paediatric nephrology centres in Turkey responded to the survey and reported 45 patients (27 girls, 18 boys) with renovascular hypertension between 1990 and 2005. The age at presentation ranged from 20 days to 17 years. The mean blood pressure at the diagnosis was 169/110 mmHg...
September 2007: Pediatric Nephrology
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